LOCUS       gnlProkkaOJLJMKHE_1    22954 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OJLJMKHE_1.
ACCESSION   gnlProkkaOJLJMKHE_1
VERSION     gnlProkkaOJLJMKHE_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 09:07:03
            Original ID  :: gnl|Prokka|OJLJMKHE_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 203655
            Orig. end    :: 226609
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22954
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12954]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12954
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..22954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="interleaved"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..22954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     protocluster    235..21467
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10234:11467]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      10235..11467
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
     CDS             401..940
                     /locus_tag="ctg1_188"
                     /transl_table=11
                     /translation="METNKPTLYWSLLMFKNWNFYIASTLKGLVFVGSQNKPIEELFEW
                     AKKRFPGSLLVEDDDKLEPYAVEITQYLEGKRKNFTVPVEYAGTQFQIAVWNALCEIPY
                     GQTKSYSDIANDINKPAAVRAVGAAIGANPVLITVPCHRVIGKNGSLTGYRGGFEMKTL
                     LLDLEKRASSEMDVPH"
     CDS             1459..2976
                     /locus_tag="ctg1_189"
                     /transl_table=11
                     /translation="MLVSLSLSSLLTLFFIMLMASGISGLLFLHPRVPLSFVRIHIGIL
                     ALPLLVSLLILANSGVSGNVGPWHLDSLACLMTFFVLAIGFIIQRFSVRYLMGDRSYRK
                     YFTLFTFTTGAASMTWLSGDLRLMVLFWGATLVGLTLLIRLNSAWQVASEAAKISGRLF
                     LLSWFSLFFAMMWLFHATGQWQLSLVVTNESLAGLGEWERTGIQLLIVLAVIIPAAQWP
                     FQRWLVESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFHGGIASIILLLLASISVLIGT
                     GISLVQVDYKRQLVGSTIGQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQAGSAVG
                     RHEVSARTNERTSYLWIMAGRILSLVIGVAFWLAAPGEGSQFISALILGWSLSVSWNQL
                     VAFGEGRIGRIVGLTVLGGAALVYFIIHHLFYKWLHTTIFQSVQPPMSAVMIVVCLLLF
                     GSALGTWVARHRSSVFFAVLYLWLVRLGEAKPKSVESHPDYLKQYIS"
     CDS             2991..5603
                     /locus_tag="ctg1_190"
                     /transl_table=11
                     /translation="MGITSVLTKDNVNKIDTDIDVQERDLNVFITSASRVIAPLWPIST
                     FAARNPWMGLENQPFDQVASWLKNTRDVDIYPSASMIRSAKNKGEIDEDFVEMGLQRWL
                     DSHSYHIPRDVAERFCHAALKLDPLPSDLLSSHELEKLVGECSGLDHIENVFMQPLSSY
                     IENQDGERLVNILDHHVIKWSKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPALSKKQ
                     RERLKGWPKEAHLALQEALFALEIPESEIQTYLEGHLLSLPGWAGMMLWRSQQSSHEHA
                     LLTEYLAVRISMEWALIKPYLPLNERSKKTISIAPLIAAWIHWGGHTLEEWSQMTAIEQ
                     NEYLSFAYSFDEKLRKKLWLEAWEQTYTDRLSQKIISKQRETGGEKSALAQLAFCIDVR
                     SEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPIIQKPQYKIKEFADEDV
                     FKKYNQRKQAIHSLSHTFKTMKQNALSSLLLPELSGPWLTLQMAARSFVPRKAGRFIRN
                     LREAWLRKPDTKLSLHHDATEAEIPVGFTDEEKVNYARQALKMMGLTENIAPLVVICGH
                     GSQSTNNPYSAALDCGACGGAAGGFNARVLAALCNLSEVREALLAEGIKIPEDTVFAAA
                     EHNTTVDELHWLYVPELSEAAQEAFEQIEAVMPKVRHHVNAERLAQLPNFQSKLKNPKA
                     EANRFAEDWSEIRPEWGLARNAAFIIGKRELTQDCDLEGRAFLHNYDWKQDESGELLAN
                     IIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLAGLPWQSV
                     MESDHEAYHSPLRLLILIQAPREYVERLLNNDSAFLQKVQNGWVRLASLDPEGCWESW"
     CDS             5680..6210
                     /locus_tag="ctg1_191"
                     /transl_table=11
                     /translation="MNVNQNKKVLFLTDIENGLEPILQEATNTSAENMLTIQSYGAGIS
                     HPYGEIMRSVIFAIYQEDVEEIFVVGTKDKKTSAGNGLTQLETMKDKIQTLDYLFQNCK
                     PEFLGGTVDEWLNENSSDTIEKSVDMIRHHPLVPSYVKVRGLFVHHKDGKPSIAEGPDA
                     KTGQAIPDHCLSR"
     CDS             6271..6561
                     /locus_tag="ctg1_192"
                     /transl_table=11
                     /translation="MSANLTDFVTKTIEDMNSFDRENMEFMKKLIRKAIDFYHLKSYEE
                     VEETHSGNVRFLHVHSMMEENMLSKMIVVTRNGKTDLDIEGVYEGYVVREY"
     CDS             6619..6993
                     /locus_tag="ctg1_193"
                     /transl_table=11
                     /translation="MKKSKGSIESEISKSITQWEKDYLGRGSVSVKTDILRDMIIVNLK
                     GILTPAEYVVCGSKEGMLSIKQTRSELVESGIEGLKDIILKITGEKVKSFHTDLSSRTG
                     ERVMVFKLCNDLEKNLEKIL"
     CDS             7490..7792
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 67.7; E-value: 1.1e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_194"
                     /transl_table=11
                     /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIGKLADFLKTEI"
     CDS             7919..9091
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 334.1; E-value: 1.4e-101)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_195"
                     /transl_table=11
                     /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDQIAHTLGITLAAAGQL
                     ITIFSLVYALSTPILMALTASMDRRKLMMYALGLFVFGNVLAFVLPGYGWFIAARIIMA
                     MGAGVVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKSVFG
                     AIALLGLIAMVVIFFTLPYTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYSVAYT
                     YLSPYLLNISGINGKLLSGVLLIFGIASLVGSKFGGYSTDKWGVPFTLVGGMTLHIVTL
                     ILLSLVTHSYIGVLVILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSMNQSMMQFAMA
                     VGAGIGGVFVENVSLASITWVGALGVMIAIIASLLIFNSQPKQALKDINQ"
     CDS             10001..10168
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: TIGR04404"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_196"
                     /sec_met_domain="TIGR04404 (E-value: 4.3e-37, bitscore:
                     123.7, seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNQKEWESVSKKGLMKPGGTSIVKAAGCMGCWASKSIAMTRVC
                     ALPHPAMRAI"
     CDS             10235..11467
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_197"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     2.4e-14, bitscore: 51.4, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.6e-21, bitscore: 74.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.6e-06, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 4.8e-05, bitscore: 21.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSLDSY
                     LPISCTLQLTNACNLSCSFCYASSGKPYPEELSSEQWILVMQKLAAHGVADITLTGGEA
                     KLIKGFKELVVVASSLFTNVNVFSNGLNWRDEEVELLSHLGNVSVQISIDGMDNTHDQL
                     RGRKGGFKESMNTIKKLSEANIPVIVAMTINESNADEVSDVVEQCANAGAFIFRAGKTL
                     SVGRATEGFKALDIDFEEMVQIQLREARHKWGDRLNIIDWEHEESSFTTDFCTPGYLAW
                     YIRADGYVTPCQLEDLPLGHILEDSMADIGSPARLLQLKCEAKNCKCIGKIELSEPDLP
                     FQKEVKAGIQE"
     CDS             11464..12954
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: skfc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_198"
                     /sec_met_domain="skfc (E-value: 4.1e-288, bitscore: 954.2,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Abi (E-value: 9.1e-13, bitscore: 46.3,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLSLVFWSILAVVGLLLFIKFKPPTIASLLLSKDEAKEISIQF
                     IKEFVGIDVENWDFYSVYWYDHDTVNKLHHLGILKKNRKVLYDVGLVESWRVRFVHQNQ
                     SFVVGVNANREITFFYADVPKKTLSGKFEQVSPETLKQRLMASPDGLWSRANMTGTGKK
                     EEDFREVSTYWYIAEAGDIRLKVTVELQGGRISYIGTEQEILTDQMSKVIRDEQVESTF
                     GVSGMLGSALAMILAILILVFMDVQTSIIFSLVLGLLIIICQSLTLKEDIQLTIVNAYD
                     ARMSVKTVSLLGILSTLLTGLLTGFVVFICSLAGNALAGDFGWKTLEQPIVQIFYGIGA
                     GLISLGVTSLLFNLLEKKQYLRISPELSNRTVFLSGFTFRQGLNMSIQSSIGEEVIYRL
                     LMIPVIWWMSGNILISIIVSSFLWAVMHQVTGYDPRWIRWLHLFIFGCFLGVLFIKFGF
                     ICVLVAHFIHNLVLVCMPLWQFKLQKHMHHDQPKHTSL"
     CDS             12973..13692
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 178.6; E-value:
                     2.5e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_199"
                     /transl_table=11
                     /translation="MQLMQVQNLSKCYRNGDGVEHLSFSIQRGEIVALLGPNGAGKTTT
                     IRCLTGLYKPDKGDILIEGSPPGDINVQKKVALIPDQPYLYPALTAAEHIQFRARGYHP
                     GKKDVKERVYHALKEVHLEEKANQLCGQLSRGQKQRVVLAGAIVQDALLYILDEPTVGL
                     DIPSKQWLSNWLKTKTDQGCSAFVSTHSLEFVIETADRVILIRDGKLMQDLYVPQFEEQ
                     AEWRKEVIRLLGEWSDE"
     CDS             13757..15100
                     /locus_tag="ctg1_200"
                     /transl_table=11
                     /translation="MPFLIMLLFVGAIGFQVSFVSRSTTWDMSIAGWVLTGVFILYTAF
                     GLFSNRLPSQMADIIWLYGTATSFSKVVYSVLFFSVTWKALLWIISAIFGDVLIVLLSG
                     DHINLLGRSIIFVGLFFIAEVWLMSVSCARTVKKMKRVYVLVFLLMLGIYSICLYRFFF
                     LQHSSGIWESIARFISGVGLVFDTLSPLYVVVFIGIITVSFMTIAFTSRQVEMKESLVK
                     EAEFWEEFQERQFGSGQIIQKPKTTWWGLQGLNGIWSFLWLELLLFKKYLFFHSIHTVM
                     LSGVFYVVIFMYPEWFYLLFFLIVSAVMLSSYYSGIVRHSQSGTLHLFPGALWKKIIIL
                     ELTNTVWLYILYCVSITFMAVGNLVYWYIYGLGIYIWFMTIRLFAFTHTNRNDIKLSLP
                     QYYKSFFMALGLSGICLYVIHLLTADWYTLVVVVCIGSLSWCLFYRFR"
     CDS             15147..15662
                     /locus_tag="ctg1_201"
                     /transl_table=11
                     /translation="MNSNGDKLSLSVQNLANTNEITIVQAIGELKKSGKDAIPVLVEAL
                     KEEGSLCNIAAAVLGEFGEDASEAAEELSCLLKSHAEDTRMAAAISLMRIGKPSLPFVI
                     KIAQESEGQSCFWASWCIAWIDPSCIEPKMYKCLKYEHEHPSGIVAPFAAEEALGKLIA
                     FQLKDKED"
     CDS             15667..16092
                     /locus_tag="ctg1_202"
                     /transl_table=11
                     /translation="MKDEQMLTEWPSHLPWLNQSQNDFTFPSDTYLLLYFWSMSCPNCH
                     QLTDKVLQDIKDMNVKVIGVHVPYIEEEKSMEVVLTYALDRGLAIPIVLDQNYEIVTTC
                     HVQGIPSFCLLSQYGQIITKTMGDVGWDKMLKKIAGL"
     CDS             16341..17318
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_203"
                     /sec_met_domain="PF00561 (E-value: 5.4e-07, bitscore: 27.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVLKIVFVSLAALVLLVSVSVFIYHHFQLNKEAALLKGKG
                     TVVDVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAGYG
                     YSEVSHDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGVDRLKVRGFHLLTSIGFHRFMPSAVYNPEVIRQSFLTDEEKEI
                     YKAINFKQFFNADMEHELLQSYQNGSKSVNLPAPKETPVLILDAVSDQNRHSKYAIQNR
                     KDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFMRKVR"
     CDS             17320..17991
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 127.8; E-value: 7.7e-39)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_204"
                     /transl_table=11
                     /translation="MKGYHILIVEDDVMIGELLQKILQREGYRVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQMSAKIKELGLGIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRMRNMLEHHYGTFTQIKHLYIDAVTKKVFNESLHDEVLFTAIERKIFFYLYEN
                     RDSILTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEMIENIYGEGYRLNTVVK
                     K"
     CDS             17988..18974
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 59.4; E-value: 5.8e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_205"
                     /transl_table=11
                     /translation="MKLKTKYQLLLFTAVISVPMLLLAVSVLMSVIYDSMFKPMNHGMP
                     FHRSFAYPAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVK
                     RADEIGELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLE
                     DQCHGQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMSGIELHYKAADQDVIWMSNALWMQRLFDNIFQNTLKHSKAEKMEVTIEHDNVFIR
                     DDGIGFDRNESSEGLGLKIIEDTCRLLAITYELHTNDSGTGFLFSKE"
     CDS             19033..19284
                     /locus_tag="ctg1_206"
                     /transl_table=11
                     /translation="MNSICLKKSSKRLSTSQAVLVTDIADTGITAAAGADIIAATAARA
                     KEDTTTVMAAVIVTNAGATAAVNPKKFLFRFWDKGFFM"
     CDS             complement(19277..20047)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 111.8;
                     E-value: 6.8e-34)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_207"
                     /sec_met_domain="Pkinase (E-value: 4.3e-32, bitscore:
                     109.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLLKKLLFDRPLKNGVILNHQYKIEECLGMGGYGLVYLCTDI
                     LTQTPYVLKQLRPTKAKKEKEKVRFQQEIKLLNSIHHPQIPGFIDEFIIDGQAYYVMQF
                     IEGENIEELLFFRKQPFTELMALQLISQLLEIIEYLHDRLIFHSDIRTPNIIINDGRLC
                     LIDFGLAKQLTPEEMEEIKVRKQDDFFDLGETLLFLLYSQYKGKKKKNGTWLEELTLTK
                     EVTLLLKRLLGIEEEYQHTASIREDLNRAIQSVT"
     CDS             complement(20133..20990)
                     /locus_tag="ctg1_208"
                     /transl_table=11
                     /translation="MVKKWLIPFAVMLSVLFTFTYSASAAGVTAITGNNSFDTAMPIGY
                     WKYKNIDTTILEAGQDEAYFTFTANKGEKVYVRSTYQSAYTGMKIEIYDKNRIPVSQGT
                     EVINPNTFSSFIYANADAQNTTDTFYVKVSRGTYTGNMYFTLSIEDRIKSGSGTFQFSG
                     VAENKGNTSLSPSGSDSSVIKVDLTNQSGIPRDAIVTRVQTTATQTPSQGNTRHLIMTS
                     ENNEWRRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATARSTMSNVKAKIDYEYDV
                     TKQF"
     CDS             21122..22306
                     /locus_tag="ctg1_209"
                     /transl_table=11
                     /translation="MRLNRQFIRTQLMAQNILSKNAPAKRENATENPAAVLEKAYSRLK
                     SQSSTGGINQFNYSKTSVSGNSGAFSKVYQSANDRTVTDTGEETVIQSQNHYESESDIR
                     IKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAVFRNVTFHGEVEAENEKVYQRGQVNQQLQVLLNRNHIHIPEGTELTFT
                     ITPIDYQVRVSGSDDQDLIKQIEQVLQSGDNSKELFLHIMKSQSSDSAQFSEEAYQKYQ
                     AAREMYEVTGYHLKDLEVIDGRYVTPEGRDLMDVYKEELEKDPVQKQTASYAISYYRSE
                     LSKIAEAGYNAIPDFILSIDYSNGSLRDVGQSKSYGTGDTGWLEALKRQTGVNY"
ORIGIN
        1 gaacaagctc tccgcgcaaa ttttcgccct tgtaaacgtt gcaagcccac taatgaaaaa
       61 atgcctgata gcgagtgggt tgatttaatt actgaataca ttgataaaaa tttcacagaa
      121 aaattaacgc tagaatcgtt agcagatatt tgtcatggga gtccgtatca tatgcatcga
      181 acatttaaaa agattaaagg cattacgctg gttgagtata tacaacaagt tagagtacac
      241 gcggctaaaa agtatttgat tcagacaaat aaatcgattg gagatatcgc tatatgtgtg
      301 ggtatagcta acgcgcctta ttttattact ttatttaaaa agaaaactgg acagacacca
      361 gcacaatttc gtcaaatgag taaaatggag gaaacgtaca atggaaacaa ataaaccaac
      421 cctttattgg tctttactaa tgttcaagaa ttggaatttt tatattgctt caactttaaa
      481 ggggcttgtg tttgtaggtt cacagaacaa accaatcgag gaattgttcg aatgggctaa
      541 gaaacgcttt ccaggaagtc ttcttgttga agatgatgat aagcttgaac cctatgctgt
      601 tgaaatcact caatatctag aaggaaagcg gaaaaacttt actgttccag ttgagtacgc
      661 cggtacgcaa tttcagatag ccgtctggaa tgcactttgt gaaattcctt atggacagac
      721 gaaatcctat tccgacattg caaatgatat aaataaacca gcagctgttc gtgctgtagg
      781 tgcggctatt ggggctaatc cggtattaat tactgtaccg tgccatcgtg taataggaaa
      841 gaatggctca ttaactggct atcggggcgg atttgaaatg aagacactgc tcctcgatct
      901 ggaaaagcga gcttcatctg aaatggatgt tcctcattga aagtgaatca tctataatgg
      961 gttggattct tttagaggaa agtaaagacc agtttactga taaacttgac aacttttaaa
     1021 atttagcata tcttatacgt aacttaataa atcgatgcag atgtttattt ttccttttaa
     1081 aatatgtagg cctttagcat tcttttcata tttaatttta aatattgata ggatgaaaaa
     1141 gtatcctaat aaaaaaggaa gagaacatag tcgatttatt tgataatcag gactatatta
     1201 aaggaaatga aaacatagca taaagtaaag accaataata aggtagcact tcaaaaaact
     1261 tcgctgaagt tagttgaagt gaagccgaca attttcagga ttcaatgatc taacataatc
     1321 attgaaattt tgaagttgtc ggcttttttg ttggaaaaaa atagagataa ataaaaattg
     1381 aaataaataa tagacaaata tgatctgatt gaaaggtctt ttgaccaata atgagtttta
     1441 aaaaagggag aatttagaat gttagtttcg ctgagtttgt catcattatt aacattattt
     1501 tttattatgc ttatggcttc tgggattagt ggactattgt ttttacatcc gcgagtaccc
     1561 ttgagttttg ttcgcattca tattgggatc ttggctttac cacttttggt ttccttactg
     1621 attcttgcca atagtggtgt gagtggaaat gttggccctt ggcacttaga ttccttagct
     1681 tgtttaatga ctttctttgt tcttgcaatt ggattcatca ttcagcgttt ttctgtacgt
     1741 tacttaatgg gggatcgatc ttatcgaaaa tattttacgc tttttacttt cacaacagga
     1801 gctgcttcaa tgacatggtt aagtggtgat ctccgcttga tggttctatt ttggggagcg
     1861 actcttgttg gattaacctt acttattagg ttaaacagtg cttggcaagt ggctagtgaa
     1921 gcagccaaaa tttctggccg gttatttttg ttaagttggt tttctttgtt ttttgcgatg
     1981 atgtggcttt ttcatgccac aggtcaatgg cagctatcat tggttgtaac aaatgaaagt
     2041 ttagctgggc tgggagaatg ggagagaaca gggattcagc tattgattgt actggcggtg
     2101 atcattcctg cagctcaatg gccgttccaa agatggttgg ttgagtctat tgttgctccc
     2161 accccagttt ctgcaattat gcatgcaggt ttagtaaatg ctggaggaat aatactaact
     2221 cgattttcac ctctatttca tggtggtatc gcttcgatta tcttacttct gcttgctagc
     2281 atttctgtat tgattggaac tggaattagt ttagttcagg ttgattataa acgccagtta
     2341 gtaggctcca cgattggaca aatggggttt atgctcattc agtgtgcatt aggcgcctat
     2401 atagcagcca ttattcatct tattttacat ggtttattca aagctacgtt gtttctacaa
     2461 gctggttcag cagtagggcg tcatgaagta tcggctcgca ctaatgaaag aacatcctat
     2521 ttatggatca tggctggtcg gattttatcc ttagttatag gtgttgcttt ttggctcgct
     2581 gctcctggag agggatctca attcattagt gcgctgatct tagggtggtc attgtccgtt
     2641 tcttggaatc agcttgtcgc ttttggagag ggccgaattg gccgaattgt cggcttaact
     2701 gttttaggag gagcagccct cgtatatttt atcattcatc accttttcta taagtggctg
     2761 catacaacca tttttcaaag tgttcaacct ccaatgtcag ctgtcatgat tgtcgtatgt
     2821 ctcttactat ttggcagtgc tttaggtacg tgggttgctc gtcatcgttc ttccgttttt
     2881 ttcgcggtac tctatctttg gttagttcga ttaggtgaag caaaaccaaa gtcagtagag
     2941 agtcacccag actaccttaa acaatatatt tcataaggag ctaatctgag atgggcatta
     3001 catccgtatt aacgaaagat aatgtaaaca agatagatac agatattgat gttcaagaaa
     3061 gggatcttaa cgttttcatt acatctgcca gccgagtgat tgcgccactt tggcctattt
     3121 ctacatttgc tgcacgtaat ccgtggatgg gacttgaaaa ccaacctttt gatcaggttg
     3181 caagttggtt gaaaaacact cgtgatgttg atatataccc tagtgcgtct atgatccgtt
     3241 cagcaaagaa taaaggtgag attgatgaag attttgtgga aatggggctg cagcgttggc
     3301 ttgattcaca ttcctatcac attccacggg acgtggcaga gcgattttgt catgctgcat
     3361 taaagttaga tcccctgcct tccgaccttt tatcatcaca tgagctggag aaattagtag
     3421 gtgaatgtag tggattggat catatcgaga atgtgtttat gcagccacta agttcgtata
     3481 tagagaatca agatggtgaa aggctagtca atatactaga tcatcatgtc attaaatgga
     3541 gtaaattata tcttgatgac tctcaagcag gctggacaat gcctaatcgt gaggaaggtt
     3601 tctatcgtgc ttggcagcat ctcattcaat atgatccagc acttagtaaa aagcagcgag
     3661 aaaggttaaa aggttggccg aaagaggcac atttggcttt acaggaagcc ttattcgcac
     3721 tagaaatccc agagtcagaa atccagactt atcttgaagg tcatttactt tcattacctg
     3781 gatgggcagg gatgatgctt tggcgctccc agcaatcgag ccacgaacat gcactcctaa
     3841 cagaatactt agcggttcga atatccatgg agtgggctct tataaagcca tacttacctt
     3901 tgaatgaacg atctaagaaa acaatttcaa ttgctcccct tatagcagct tggattcatt
     3961 ggggtgggca tacattagaa gaatggtcac agatgacggc cattgaacaa aacgaatatt
     4021 tatcatttgc ctacagcttt gatgagaaac ttcgcaagaa actttggtta gaagcttggg
     4081 aacaaacgta cactgatcga ttaagccaga agatcatctc gaaacaacgt gaaaccggcg
     4141 gtgaaaaatc tgcattagct caattagcat tctgcatcga tgtacgatca gaaccttttc
     4201 gtcgtcaact agaaaaagaa ggtccgtttg aaacgattgg tattgctggt ttcttcgggg
     4261 tgccaattgc aacttgtgaa cttggcagta aacacagtca tgcttccttg ccgatcatac
     4321 aaaaaccgca atataaaata aaagagttcg cagatgagga tgtattcaaa aaatacaatc
     4381 aacggaagca agcaattcat tctttaagcc atacctttaa aacgatgaag cagaatgcgc
     4441 tttcgagctt actactgcct gagctaagcg gaccttggct tactctgcaa atggcagccc
     4501 gtagctttgt gccaagaaag gcgggtcgtt tcattcgtaa tctccgtgag gcttggttac
     4561 gcaaacctga tacaaaactc tcgcttcatc atgatgctac agaggcagaa atacctgtgg
     4621 gttttactga tgaagaaaaa gtgaactatg ctcgccaagc attaaaaatg atggggttaa
     4681 cagagaacat cgcaccattg gtcgtaattt gcgggcatgg cagtcaaagc actaataatc
     4741 cttattctgc agcccttgat tgtggtgcct gcggtggagc ggccggtgga ttcaatgcaa
     4801 gagttttagc tgctttatgt aatctatcag aggtacgaga agctctttta gctgaaggaa
     4861 ttaaaattcc tgaggatacg gtttttgcag cagctgaaca taatacaaca gtagatgaat
     4921 tacattggct ttatgtacca gagctttccg aagctgcaca agaagcattt gaacaaattg
     4981 aagccgttat gccgaaagtg agacatcatg taaacgcaga acgtctagcc caattaccga
     5041 atttccaatc gaagctaaaa aatccgaagg ctgaggcaaa ccgatttgcg gaagattgga
     5101 gtgagatacg tccggaatgg ggactggctc gtaatgccgc ttttattatc ggtaaacgtg
     5161 aactaactca ggattgtgat ttggaaggca gagcctttct ccataattat gattggaagc
     5221 aggatgaaag cggtgaactc ctagcaaata ttattgcagg acctggaact gtagcccaat
     5281 ggattaattt acaatattac gcatcaacgg tagcacctca ttattatggc agcggaaata
     5341 aagcaactca aaccgttact gcaggtctcg gcgttatgca ggggaatgca agcgatttgt
     5401 tagccggact gccttggcaa tccgtcatgg aatcagatca cgaggcctat cattctcctc
     5461 ttcgtttatt gatactcatc caagcaccta gagaatatgt agaacggtta ttaaataatg
     5521 attcagcatt tctgcaaaaa gttcaaaatg gatgggtccg actggctagt cttgatccag
     5581 aaggatgttg ggaaagctgg taatgatgaa tctaagcatt tatcaaatgg atttgttatt
     5641 caaaataaaa atgataaaca taaggaagag gtgtgctgta tgaatgtaaa ccaaaataaa
     5701 aaagtattat ttttgacgga tattgaaaac ggtttggagc ctattttaca agaagcgact
     5761 aacacttctg cagagaatat gttgactata caaagctatg gtgccggtat ttcacatcct
     5821 tatggagaaa tcatgaggtc tgttattttt gcgatttacc aggaagatgt tgaggagatt
     5881 tttgtagtag gaacaaaaga taagaagact tccgcaggta atggactaac tcaacttgaa
     5941 acaatgaaag ataaaataca aacattggat tatctttttc aaaattgcaa gcctgaattt
     6001 ttaggtggta cggtcgatga atggctaaat gaaaatagca gtgacaccat tgaaaaaagt
     6061 gttgatatga ttcgacatca tcccctagtg ccgtcatatg ttaaagttag aggtttattc
     6121 gttcatcata aggatggaaa accctcaatc gcggagggtc ctgatgctaa aacaggtcaa
     6181 gccatacctg atcattgctt gtcacgatga aatacaggtt caacttctaa acgcacccat
     6241 atatggagaa agcagttcta aggagattgt atgagcgcta atttaactga ttttgtcacg
     6301 aaaacaatag aggacatgaa ctcgtttgat cgtgaaaata tggaatttat gaaaaaacta
     6361 attagaaaag caattgattt ttatcatcta aagtcttatg aagaagttga ggaaacccat
     6421 tcaggaaatg ttcgattttt gcatgtccac tctatgatgg aagaaaatat gttatccaaa
     6481 atgatagtgg tcacaagaaa cggtaaaact gatttggata ttgaaggtgt atatgaagga
     6541 tatgttgtaa gagaatatta atgagacgaa atcacaaata gaatatgcca atttttttgc
     6601 tcaggagatg tattagatat gaaaaagtct aagggttcta ttgaatcaga gatcagtaag
     6661 tccattactc aatgggagaa ggattatctt gggcgggggt ctgtatctgt taagactgat
     6721 atactgcggg acatgatcat cgtcaattta aaagggattt taacaccagc cgaatatgta
     6781 gtttgtggat caaaagaggg tatgttatct atcaaacaaa ctcgttcgga gttagttgaa
     6841 tcaggtatag aaggccttaa ggatattatc ttaaaaataa ccggagaaaa agtgaaaagt
     6901 tttcatactg atttaagctc ccggacaggt gaacgagtga tggtatttaa attatgtaat
     6961 gatctagaga aaaatttgga aaagatctta taatctaaag aaaataaatg ttaagacggt
     7021 atggaatttg ttgtgaattg aacataaaga actgccgatt cttttgtttt acaattatgg
     7081 tatcattgat aacttttatt catatcctaa gcggacataa agagatgtca attcatagta
     7141 cactgacttg ttattcctgt cgaaagatct aacatccgct gttgttatga gcggatgttt
     7201 ttttacatct attttaaata catgaatttg atgctggtga ttagtcactt gaacaatatt
     7261 aaattcattt taattgaaaa catccttgtc accttccagg ttcacccaag tgttttgtga
     7321 aatgattatg agaccaattt cgtaaagctt gatgataaat ttaagcggtg aacaaaattg
     7381 atatgctgtc ttcagtttca tttcacggaa ttagtcagag ataaaccttt aattaaatat
     7441 atccaaaaaa cggattgaca tatcgaaata taacgatata ataatcgata tggaaccaat
     7501 tgaagtattc aaagccttat caaatgaatc aaggctgcaa attttacaat ggctgaagga
     7561 gcccgatcgt cattttgcac cccatgaagg gattgatatg aacacaatcg gggtatgtgt
     7621 cagtcaaata acagacaaat tgaaaatgac gcaatcgaca gcttctcaat atcttaccat
     7681 ccttttaaga gccggcctaa ttaaggcgga gcgaatcgga aagtacacgt attacaaaag
     7741 agatgaagaa gccattggga aacttgctga ctttcttaaa acagagatat aaaaataaac
     7801 atcaaaagat gtttattttt atatcataca tatcgacata ttacgatgtg tttatttttt
     7861 ataataacat atcgataatt cgtgatatgt ttattaataa ttaaggagtg aatgttttat
     7921 gtctaacact tggaaaattt atattttagc cattgtcagc tttttagttg gaacctcaga
     7981 gtacatcatt tccggaattt tggatcaaat tgctcatact ctcgggatca ctttagctgc
     8041 cgcgggccag cttattacca ttttctcact tgtatatgct ctttctacac ccatacttat
     8101 ggcgttgaca gcaagtatgg atagacgcaa attgatgatg tatgccctag gtttgtttgt
     8161 gttcggtaat gtcctggctt ttgtactgcc tggttatgga tggtttattg cagcgcggat
     8221 cattatggcg atgggagcag gtgtggttgt tgtcaccgca ttaacgattg cggctaagat
     8281 tgcatcggaa gggaagcagg gcagtgccat cgctacggtc gtgatgggat ttaccgcttc
     8341 tttaatcatt ggtgttccgc ttggaagaat gatagcagta gcattaggct ggaagtctgt
     8401 atttggagca attgctttgt tgggattgat cgcaatggtc gttattttct ttactcttcc
     8461 gtatactgaa ggggataagc ctgtgccttt gcttcaacag cttgctcttt tcaaaaaacg
     8521 gaaagttgct atgggattat caatcacttt cttctggctc gggggatatt ctgttgctta
     8581 cacttatttg tcaccgtatc tcttgaacat ctcaggtata aatggcaagt tgcttagcgg
     8641 tgttttgctt atatttggaa ttgctagttt ggttggatca aagtttgggg gatatagcac
     8701 cgataaatgg ggagtaccct ttacactcgt tggcgggatg acgttgcata tcgtcacact
     8761 gattctgctg tcacttgtta ctcattccta tatcggagtg ttggtgattc tcatattatg
     8821 gtcgtttgcc gcatggtcca ccggtccgac acagcaattt cacctggcta caatagaacc
     8881 ggaaatgtca ggtgttttgc ttagcatgaa tcagtcaatg atgcaattcg ccatggcggt
     8941 cggcgcaggt ataggagggg tttttgtgga aaacgtatca ttggcctcga ttacctgggt
     9001 tggtgcgtta ggggttatga ttgcaattat tgcatcattg ctgattttca attcgcaacc
     9061 gaaacaagcg ctaaaagata tcaatcaata atttcgaaag ttctaacatc cgctcgttat
     9121 acaagcgggt gtttttttta gcgtagtcag tccatgcatg agtcttccaa gggccgacat
     9181 cgttctgtat gtgtcgaagg tgcactgaag ctgaatgaga tttcttaagg ctttgccgcg
     9241 gcgagctgaa gtacagtacg attgccttga tcgaacactg gaaacacaag agaacgtaaa
     9301 cctgaacatc cgcgtaaacg tcaaggaagt tgccacttgg ggagtaaaca cttgcatcat
     9361 ctcgctgaaa ggcctagaca atgcggatga cagattcgta ttgccggaag taaacacagc
     9421 gcttgctctg tttccgttgt cgattgcagc tgattgctta ctaatgctgc cctgcatctc
     9481 ggttgtgatg tcgataagca gcgtaatgaa gagtgttact gtggagtaag atgtttaacc
     9541 cctctggata ttttagccga aggggttttt agtatagata tttgatttaa attacaggag
     9601 acttcattca tttaaccaaa gtcattgctt tcttaatcac taaagtttat ttgaaaataa
     9661 tctcttgatt taatttcctc gaagagattt tttgtcaatc tattaggcat cagaattttt
     9721 ataacataat ggaccgtctt tttgacgttt tgtttataga acaagaaaat attcaaaaca
     9781 taagtggaaa attaggggtg agctcctgtt tttctcgaga ggatagcttg tcagcttttc
     9841 tatttttaaa gggttaaaat attctattta tactaattaa tgtaattttt aggataatat
     9901 acaaaatccc ccttacttcg acaattgcaa tctggtatta tcgtatcgca tgggagctat
     9961 gtcaatagac tctatgcaaa aattgagagg aggtttactt atgaaaagaa accaaaaaga
    10021 atgggaatct gtgagtaaaa aaggacttat gaagccggga ggtacttcga ttgtgaaagc
    10081 tgctggctgc atgggctgtt gggcctcaaa gagtattgct atgacacgtg tttgtgcact
    10141 tccgcatcct gctatgagag ctatttaaca tttgagaata gggagttgag cgtatttgct
    10201 tatactcctt attttctctt aagggggatt ttatatgtca tatgatcgtg ttaaagattt
    10261 tgatttgcca gagttagcgg ttcatttaca gcctcatggt gctgtaatga ttgatagaaa
    10321 aagtatgttt tatttcagac tcagtggacg tggagcacag ttggcgtttc tgttatcaaa
    10381 aaacaaaaat cttcataaaa cggcacgtat ttgggagatt atgaaaaaag aagagatgag
    10441 tgctgaccaa ttaaaagaag agcttagtgc ccatccattt acggaggctt ggacggaagg
    10501 gctgttagat cagcctttac acgtttcggg ttcgctagat tcatatttac ctattagttg
    10561 taccttacag ttgacaaatg cttgtaattt aagctgttcg ttttgctatg ccagctcagg
    10621 taaaccatat cctgaggaat tatctagtga acaatggata ttggttatgc aaaagctagc
    10681 agcccatgga gttgctgata ttacgctgac cgggggtgaa gcaaagctga tcaaagggtt
    10741 taaagaatta gtcgttgttg caagttcgtt gtttaccaat gtgaatgtat ttagtaatgg
    10801 attgaactgg cgagatgaag aagttgaatt acttagtcac ttaggcaatg tttctgtaca
    10861 gattagtatt gatggtatgg ataatacaca tgaccaatta agaggcagaa aaggcggctt
    10921 taaagaaagt atgaatacca ttaaaaaatt atcagaagca aacattccag tgattgtcgc
    10981 tatgaccatt aatgagtcca atgctgatga agtatcagat gtggtggagc aatgtgccaa
    11041 tgcgggtgct tttatctttc gtgcaggaaa aacgttatct gttggacgtg cgacagaagg
    11101 ctttaaggct ttggatattg attttgaaga aatggttcaa atacagctta gggaagcacg
    11161 tcataaatgg ggagatcgcc tgaacataat tgattgggag cacgaagaga gttcgttcac
    11221 aacagatttt tgtacaccag gatatcttgc ttggtatata agagcagatg gatacgtaac
    11281 tccttgccaa ttagaagatt tgccgctagg gcatatttta gaagatagca tggctgacat
    11341 tggttcacct gctcgtttgc ttcagttaaa atgtgaagca aaaaattgca aatgtatagg
    11401 gaaaattgag ctatctgaac cggacttacc ttttcaaaaa gaagtcaagg cagggattca
    11461 ggaatgaata gtctatcatt ggtgttctgg agtattttag cagttgttgg attactgtta
    11521 tttattaaat tcaaaccccc aacaattgct tcactactct taagcaaaga tgaggcaaaa
    11581 gaaataagca ttcaatttat aaaagagttt gttgggatag atgtagagaa ctgggatttt
    11641 tattcagtat attggtatga ccacgataca gtaaataaac ttcatcactt aggcatactt
    11701 aagaaaaata gaaaggtttt atatgatgtt gggttggtcg aatcatggag agtccgtttc
    11761 gttcaccaga atcaatcatt tgtagttggt gtcaatgcca atcgagaaat cacttttttt
    11821 tatgcggatg ttccgaaaaa aaccctttcg gggaagtttg aacaagtttc tccagagaca
    11881 ctcaagcaga ggttaatggc ttcacctgat ggactttggt ctagagcaaa tatgactggt
    11941 actggtaaaa aagaggagga ttttcgcgag gtcagtactt attggtacat agcggaagcg
    12001 ggagatattc ggctcaaagt gactgttgaa ttacagggcg gccgaatttc ttatattggt
    12061 actgaacaag aaatactaac agatcaaatg agtaaagtca ttcgagatga acaagtggaa
    12121 tcgacattcg gagtatctgg tatgctgggt tcagctttag cgatgatcct tgcgattctc
    12181 atccttgtat ttatggatgt gcaaacaagc ataatcttca gtcttgttct gggtttgttg
    12241 attataatat gccagtcatt gacgctgaaa gaagatattc aattaacaat tgtaaatgct
    12301 tatgatgcaa gaatgagtgt caaaacggtc agtttattag gtattttgtc tacacttctt
    12361 acaggattat taacaggatt tgtagtattt atatgttcat tggcaggaaa tgcgcttgct
    12421 ggtgattttg gatggaaaac gcttgaacaa ccaatagttc agattttcta tggaatagga
    12481 gcagggctca ttagtttagg agtgacttct ctgctgttta acttattgga gaaaaagcaa
    12541 tatttacgaa tttcacctga gctttctaac cgaactgtct ttctatcagg ttttaccttt
    12601 aggcaaggat tgaatatgag catacaaagt tcaattggag aagaggtcat ctatcggcta
    12661 ttaatgattc cagtcatttg gtggatgagt ggaaatatcc tcatctccat tattgtatct
    12721 tcctttttat gggcggtgat gcaccaagta actggatatg acccaaggtg gatacgttgg
    12781 ctgcatctat ttatattcgg ttgctttctg ggagttctct tcatcaaatt tggttttatt
    12841 tgtgtattag tagctcattt cattcataat ttagtactcg tctgtatgcc gctgtggcag
    12901 ttcaagcttc agaaacatat gcatcatgat cagccaaagc atacttcact ctaatgatta
    12961 ggagaagatt tgatgcaatt gatgcaagta caaaatttaa gcaaatgcta tcgaaatggt
    13021 gatggggttg aacatttgtc tttctcaatt caacgaggag aaatcgtggc gctattgggg
    13081 ccaaatggag ctggaaaaac aacgacaatt cgatgtttga caggtctcta taagccggat
    13141 aaaggagata tcctcattga gggttctcct ccaggagata taaatgttca aaaaaaagtc
    13201 gcgcttattc ctgatcagcc atatttgtat cccgctttaa ctgctgctga acatattcag
    13261 tttagggcaa gaggatatca tccaggtaaa aaagatgtaa aagaaagggt ttatcatgca
    13321 ttgaaggaag tgcacttgga ggagaaagca aaccaattgt gtggtcagct gtcaagaggc
    13381 caaaagcagc gggttgtcct ggcgggggcg attgttcaag acgctttgct gtatatatta
    13441 gacgaaccga ctgtgggcct tgatatccca tcaaaacagt ggctctctaa ctggttaaaa
    13501 actaaaaccg atcaagggtg ttcagcattt gtatcaactc atagtctaga gtttgttata
    13561 gagacagcag acagggtgat attaattaga gacggcaaac tcatgcagga tttgtatgtt
    13621 cctcaattcg aagaacaagc ggaatggaga aaagaagtga ttcgtcttct aggggaatgg
    13681 tcagatgaat aatatcattt cttttttatg gcttcagtca aaaaggcgtt ttgtaagtca
    13741 aggtcaggaa aaaaaaatgc cttttttgat catgctcctt tttgttgggg ccatcggatt
    13801 tcaagtaagt tttgtttcta gatctacgac atgggatatg agtattgctg gttgggtact
    13861 tacaggtgtt tttatccttt atacggcatt tggacttttt tcaaatcgat taccaagtca
    13921 aatggcagat attatatggc tttatggcac tgccacatct ttttcaaaag ttgtgtatag
    13981 tgttttattt ttcagcgtca cttggaaggc gttgctttgg atcatctcag ccatattcgg
    14041 tgatgtatta attgtgcttc tgtctggtga tcatatcaat ttattaggcc gatccataat
    14101 ttttgtaggg ctctttttta tcgctgaagt gtggttgatg tcggtctctt gtgccagaac
    14161 agtgaagaaa atgaaaaggg tatacgtttt agtctttctt ctaatgttag gcatttactc
    14221 catatgtctt tatcgcttct tctttctcca acattcatct gggatatggg agagcattgc
    14281 ccgttttatt agtggcgttg gattagtgtt tgatacattg tcaccgttgt atgtggttgt
    14341 atttattggg attatcacag tctcttttat gacaattgct tttacgagcc gtcaggtaga
    14401 aatgaaggaa tcgttggtga aagaagctga attctgggag gaatttcaag aacgtcaatt
    14461 tggttcaggt caaattatac agaaaccaaa aacgacttgg tggggcttgc aaggtctaaa
    14521 tggcatttgg tcttttctgt ggttggaact gttgcttttt aaaaaatatt tattttttca
    14581 tagcattcat acggtcatgc tcagtggcgt cttttatgtc gtcattttca tgtatccaga
    14641 atggttttat cttcttttct ttcttatcgt ctcggcagtc atgttaagtt cctattattc
    14701 aggaattgtc agacattctc aatcaggcac ccttcattta ttccccggtg ccctttggaa
    14761 aaaaatcatt attctagagc tgacgaatac agtctggttg tatattcttt actgtgtttc
    14821 tattactttt atggcagttg ggaatttagt ttattggtat atatatggct tagggatata
    14881 tatatggttc atgacaataa ggctttttgc ttttacccat acaaaccgaa acgatattaa
    14941 gctttcattg cctcaatact acaagtcatt ttttatggca ttaggcctga gcggcatttg
    15001 tttgtatgtc attcatttat tgactgctga ctggtataca ttagtggtgg tcgtctgcat
    15061 agggagccta agttggtgcc tgttttatcg tttcagatag tggttatgta gagttattgt
    15121 tttaaaacga ggagaggggc tcttttatga attcaaatgg tgataaattg tcgttatctg
    15181 ttcagaattt agcgaataca aatgagatca caattgttca agcgataggt gagctaaaga
    15241 aatcgggaaa agatgcaata ccagttttgg ttgaggcctt aaaagaggaa ggctctttgt
    15301 gtaatattgc tgcagctgtt ttaggtgagt ttggggaaga cgcgagtgaa gcagcggagg
    15361 agctatcatg tttattaaaa agtcatgccg aagatacaag aatggcagcg gcgatttcat
    15421 taatgagaat cgggaagccc agtctgccct ttgtcatcaa aatcgctcaa gaaagtgaag
    15481 ggcaatcgtg cttttgggca tcttggtgta ttgcatggat tgatccgtct tgcattgaac
    15541 ctaagatgta taaatgtcta aaatacgagc atgaacatcc ttcaggaata gttgctccgt
    15601 ttgcggctga agaggcgtta ggaaagctga ttgcttttca gctgaaagat aaggaggact
    15661 gaaaggatga aagatgaaca aatgttgact gaatggccaa gtcatttacc atggttgaat
    15721 caatcacaga atgattttac atttccaagt gacacatatc ttcttcttta tttttggtca
    15781 atgagctgtc caaactgtca ccaattaaca gacaaagtcc ttcaagatat aaaggatatg
    15841 aatgtgaaag taatcggagt acatgtcccc tatatagaag aagagaaatc tatggaggtt
    15901 gtcttgacgt atgctcttga taggggacta gctattccga ttgtattaga ccaaaactat
    15961 gagatcgtca caacttgtca cgtacaaggc atccccagct tttgtctatt aagtcaatac
    16021 ggtcagatca ttactaaaac gatgggagat gttggttggg ataagatgtt aaaaaagatt
    16081 gcaggcttgt gaaattttcc gtcttgtatg tgcgacaaac ggttgaatat tatgatgaaa
    16141 cggtccttcc tataagcagg aaggtttttt aatgaaatat ttttttatta gtaggtaaat
    16201 tcatcaaatg ttctgctatg ctccaaatgt acacctttcc gtaagggcaa agttaaatgt
    16261 gaaaataaaa ctgttccaaa gttaatcaga aatttatttt catattgtat cctttcagta
    16321 tcacgtgaaa ggagcatcat atgaaaacat tatggaaagt cctaaaaatt gtttttgtca
    16381 gcttggctgc tttggttttg cttgtatccg tctcggtatt tatttatcac catttccagc
    16441 taaataagga ggcggcactg ctgaaaggta aaggcacagt agtcgatgtt gacggtaaaa
    16501 agatgaatgt gtatcaagag ggaagcggga aggatacgtt tgtgtttatg tccggttcgg
    16561 ggattgctgc gcctgcttat gaaatgaagg ggctgtacag caagttttca aaagaaaata
    16621 agattgctgt tgtagatcgg gcaggttatg gatacagtga agtgtctcac gatgacagag
    16681 atattgatac ggtattggaa cagacgagga aagcgcttat gaaaagcgga aataagcctc
    16741 cttatatttt aatgcctcat tcgatatccg ggattgaagc gatgtattgg gcacagaaat
    16801 atcctaagga aatcaaggcc attattgcga tggatattgg attgccccag cagtacgtca
    16861 cgtataaatt gagcggagtt gacagattga aagtgagagg gttccacctg ttaacctcga
    16921 ttggttttca tcggtttatg ccttccgctg tatataatcc tgaggtgatt cggcagtcgt
    16981 ttttaactga tgaagaaaaa gaaatctata aagccattaa ctttaagcaa ttttttaatg
    17041 cagatatgga gcatgagctt ttacagtctt accaaaacgg cagcaaatct gtgaatctgc
    17101 cggcaccaaa ggaaactccc gtcttgattt tagatgcggt ctctgaccaa aatagacatt
    17161 caaagtatgc tatacaaaac cgaaaagact atgaagcgtt tgcggctcaa ttcaatactg
    17221 ccgatataaa ggaactgagg ggaacacaca gtatttattt atatcagcct gatcaaatat
    17281 ataaactgtc catggagttt atgagaaagg ttcgctagga tgaagggata tcatatttta
    17341 atcgtggaag acgatgtgat gattggtgaa ttgctgcaaa agattttgca gcgtgaggga
    17401 tatcgtgtga tatggaaaac agatggagcg gatgtgcttt cggtgattca gaaggtggat
    17461 ttggtcatta tggatgtgat gctgccgggt gaagacgggt atcaaatgtc tgcaaaaatc
    17521 aaagagctgg ggctgggcat tccggtaatt tttctttcgg cccgtaatga tatggacagc
    17581 aagcttcaag gtttacagat cggcgaggat tatatggtaa agccctttga tccgagagag
    17641 ctgctattaa gaatgcggaa tatgcttgag catcattatg ggacctttac gcaaatcaaa
    17701 catttgtata ttgatgcggt aacgaaaaaa gtgttcaatg aaagcctgca tgatgaggta
    17761 ttatttactg cgattgagcg gaaaattttc ttttatttat atgaaaatag agacagtatc
    17821 ctgacaaagg aacatttctt tgaatatcta tggcaactcg aagatagaaa cccgaatatt
    17881 gtcaatgtgc atattaaaaa aattagagct aaaatcaatg atcaagcggg tgagatgatt
    17941 gaaaatatat atggagaagg gtatcggctg aataccgttg tgaagaaatg aagcttaaga
    18001 caaaatatca gttgttattg tttacggccg tcattagtgt tccaatgcta ttgctggcgg
    18061 taagtgtttt gatgtcggtg atttatgaca gcatgtttaa accgatgaat catggtatgc
    18121 cctttcacag gtcgtttgcg tacccggcaa tgatcgttgt atttttgata tcactcttat
    18181 tgttagcttt tttattttca aagtcgattc attctctgtt gcataaaatc aatctattaa
    18241 atcaaaccat tcggcatttg gcgagtgatc aaagggtgcc cgataaaatt gaagtgaagc
    18301 gtgctgatga aatcggggaa ctgatcaagt cggtcaattt gttaattgaa cggacgacat
    18361 atcgtgaact ggagctgaga cagcaagagg aaatcaaaaa ggagcttttg caaaaactgc
    18421 ggcatgacat taatacacct ttaacggctc tcaggctgca gttattttat ttggaagacc
    18481 aatgtcatgg tcaggctgta ttcgaatcat tgtatcagca aatcgaatat atctcggaat
    18541 taaccaatga attcaatcta tattccgctg agacgctgga aagctcttat attgtaaatg
    18601 aagaagtgcg tctaaacgag ctattagaaa cagcggtgaa aaagtgggat tatttataca
    18661 gtatgagtgg gattgagctg cactataagg cggcagatca agatgtgata tggatgagca
    18721 acgcgttatg gatgcaaagg ctgtttgata atatttttca aaatacgtta aagcattcaa
    18781 aagctgaaaa gatggaagtc acgattgaac atgacaatgt ttttattcgt gatgacggta
    18841 ttggatttga tcggaatgag agcagtgagg gacttgggtt aaagattatt gaggatacat
    18901 gcaggctgct tgcgattact tatgagctgc atacaaatga tagcggaacg gggttcttgt
    18961 tttcaaaaga gtgaccccgc tgatgttttt ctttctccta taaaatttat ataataggga
    19021 gaaagaaatg gggtgaacag catatgttta aaaaaatcat caaaacgatt aagtacctct
    19081 caagcagttc tagtgaccga tatcgcagac accggcatta cagcagcagc cggcgcagac
    19141 attatcgcag ctacagcagc tcgggcaaaa gaagacacta cgaccgttat ggcggcagtc
    19201 atcgttacaa acgccggagc tacagcagca gttaatccaa aaaagttctt gttccgcttt
    19261 tgggacaagg gtttttttat gtgaccgatt gaatggcccg gtttagatcc tcgcgaatgg
    19321 aagcggtgtg ctgatactct tcctcaatgc ccaataatct tttcagcagc aaggttactt
    19381 cctttgtcag tgttaattcc tccagccaag tgccgttttt cttctttttt cctttatatt
    19441 gagagtacag caggaataac agcgtttctc cgagatcgaa gaagtcatcc tgttttcgta
    19501 cctttatttc ctccatttct tcaggagtca attgtttggc aaggccgaaa tcgatgaggc
    19561 agagcctgcc gtcattgatg atgatattag gcgttctgat gtcgctgtgg aagataaggc
    19621 gatcatgcag gtattctata atctcaagca gctgcgaaat cagttgtaat gccataagct
    19681 ctgtgaacgg ctgttttcga aaaaataata attcttctat attctctccc tcaatgaact
    19741 gcatgacata ataagcctgt ccgtctatga tgaactcatc tatgaagccc ggaatttgcg
    19801 ggtggtgaat gctattgagc agttttattt cctgttggaa tcggactttc tctttttcct
    19861 ttttcgcttt tgtcggccga agctgtttta agacataagg tgtttgagtt aggatatcgg
    19921 tgcacaaata aaccaaaccg tagcctccca taccgaggca ctcttcgatt ttgtattgat
    19981 gatttaagat aacgccgttc tttagagggc ggtcaaatag cagttttttt agaagtttta
    20041 atgccatgtc tgcacttccc ttggttgtac tgactatagt ttaccttcta gacagagaat
    20101 aaaaaagagc cggatcaccg gctcggtata agttaaaact gctttgtcac gtcgtattca
    20161 taatctattt ttgcttttac gttgctcatc gtcgatctgg ctgtcgctaa tgtattatat
    20221 ttaaaactcc atacctttgc cacactgagt tgatctgaca aagagatatc ataagaccct
    20281 gaagtcgagc tgtttacaag agcacggcgc cattcgttgt tttcgctcgt catgatcagg
    20341 tggcgtgtat ttccctggct tggtgtttga gtggcggttg tctgaactct ggttacaatg
    20401 gcatcacgcg gtatcccgga ttggtttgtt aaatcaacct tgatcacgct ggaatcagaa
    20461 cctgaggggc taaggcttgt atttccttta ttttcagcaa cgccgctgaa ttggaatgtt
    20521 ccgctgcctg atttgattcg gtcttcaatt gaaagtgtaa aatacatgtt tccggtatag
    20581 gtgcctcgtg acactttcac ataaaaggta tccgtcgtgt tttgggcgtc tgcatttgca
    20641 taaataaaag aagaaaacgt attagggtta atgacttctg tcccttgaga aacaggtatt
    20701 ctattcttat cataaatttc aattttcatc cctgtatacg cgctctggta tgtactcctc
    20761 acgtatactt tttctccctt attagccgta aaagtgaaat aggcttcatc ttgaccagct
    20821 tccagtattg ttgtatcgat atttttatat ttccaataac cgatcggcat tgcggtatca
    20881 aatgaattgt ttcctgtgat agcagtgact ccggcagctg atgccgaata cgtaaaggtg
    20941 aataagacag acagcataac agcgaatgga ataagccatt ttttcaccat gcaaacaacc
    21001 tccttttatt tccatcatac ataataacga tttaggtgta aataaatgtt ttttgaggtt
    21061 aatatataca ttatctttgc cgataaaaaa gaataagaga gaatactcgg gagggaattc
    21121 aatgcgtctg aatcggcaat ttatccgcac tcagctgatg gcacagaaca tattgagcaa
    21181 gaatgcgcct gccaaacggg agaatgcgac tgaaaatcca gcggcagttc tggaaaaggc
    21241 atacagcagg cttaagtcac aatcttcaac tgggggaatc aatcagttca attattctaa
    21301 aaccagcgtg tcgggaaaca gcggggcgtt cagcaaagtg tatcaatcag cgaatgatcg
    21361 aacagtgaca gacacagggg aagaaacagt gattcaatcc caaaaccact atgaatctga
    21421 gagtgatatc agaatcaaaa tactagatga aaaatacagc aggatgaatg cgattaataa
    21481 aacaaagtct gatccattag gctatattaa ggataagtac caaaattcaa agtctcctta
    21541 tttcagaagt gatctgtcag ctgcagaaag acaggccgct tacgataatg aaacagaatg
    21601 gttattcaaa gggaaggcgc aaaactataa ccttcaggat gctgtgtttc ggaatgtcac
    21661 atttcatggg gaagtggaag ctgagaatga aaaggtgtat cagcggggac aggttaacca
    21721 gcagctgcaa gtactgttga atcgaaacca tattcatatt ccagagggga cagagctgac
    21781 gtttacaatc acaccgattg actatcaggt gcgggtaagc gggtcagacg atcaggatct
    21841 gatcaagcaa attgagcaag tgctgcaatc tggagacaac agcaaagaac tatttttgca
    21901 catcatgaaa agccaaagca gtgattcagc acaattttcc gaagaggcct atcaaaagta
    21961 tcaggctgct cgtgagatgt atgaagttac aggctaccat ttgaaggatt tagaagtgat
    22021 tgatgggcgg tacgtcacgc ctgagggacg tgacttaatg gatgtatata aggaagagct
    22081 tgaaaaagat ccagtgcaga aacaaacggc ttcttatgct atatcttact atcgttcaga
    22141 gctcagtaaa atcgcggaag ccgggtataa tgccattccg gatttcatcc tttcaattga
    22201 ttacagcaat ggatctctga gagatgtggg acaaagcaag agctatggga ccggagatac
    22261 cgggtggctt gaagcattaa agcgtcaaac gggtgtgaat tattaggtaa gctgttcatg
    22321 taggacagct tattttttat gagaatctaa ggggtgaatt aatcccaata ttcaaataat
    22381 tttattattt ttatataaaa gattttaaaa gaagtgaacg attcaaaact ctgaacaaag
    22441 gtgtttgcct gaaaaaaaca attgtatttt ccagagaaat ttattatgat gaaataagta
    22501 atttaggaga ttatataaca attttaagtt tgaattttct gattgttatc actgattcat
    22561 gtgaaggcaa gcaggtctgc tgttttctca tttatgagta ttttgttagg aggaggaaga
    22621 ggagtggcaa ataaagaatt aaagaggggc ctgggcgcgc gccatattca gatgatcgcc
    22681 ttgggcggta caatcggtgt tggcttgttt atgggttctg ccagcacgat ttcatggact
    22741 ggcccatctg tccttctggc ttatgcaata tgcggaattt ttatcttttt tattatgcgt
    22801 gcgatgggtg aaatgctgta tgtcgagccg agcacaggtt cttttgcgac gttcggccat
    22861 caatatattc atccgatggc aggttatata acagcatgga gcaactggtt ccagtggatt
    22921 atcgtcggca tgtcagaaat tatcgctgtc ggtt
//
