## Fri May 2 01:51:38 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_012955485.1/GCA_012955485.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_012955485.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_012955485.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs MHFCBNDO_00001 543734.LCABL_00010 0.0 878.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,3F3YA@33958|Lactobacillaceae 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N MHFCBNDO_00002 543734.LCABL_00020 1.02e-260 716.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,3F3ZQ@33958|Lactobacillaceae 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 MHFCBNDO_00004 543734.LCABL_00030 4.07e-43 140.0 COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,4HNMC@91061|Bacilli,3F803@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein YaaA yaaA - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 MHFCBNDO_00005 543734.LCABL_00040 9.09e-260 712.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,3F3Q1@33958|Lactobacillaceae 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N MHFCBNDO_00006 543734.LCABL_00050 0.0 1294.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,3F48M@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim MHFCBNDO_00007 543734.LCABL_00060 0.0 1657.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,3F3YM@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV MHFCBNDO_00008 543734.LCABL_00070 5.22e-163 456.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,3F4M3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC MHFCBNDO_00009 543734.LCABL_00080 5.2e-98 285.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB MHFCBNDO_00010 543734.LCABL_00090 1.36e-65 199.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,3F6ZY@33958|Lactobacillaceae 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 MHFCBNDO_00011 568703.LGG_00012 1.54e-114 331.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,3F66N@33958|Lactobacillaceae 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB MHFCBNDO_00012 1423732.BALS01000057_gene2844 3.26e-48 154.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,3F7CY@33958|Lactobacillaceae 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 MHFCBNDO_00013 543734.LCABL_00140 0.0 983.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,3F5E6@33958|Lactobacillaceae 91061|Bacilli C Cytochrome bd terminal oxidase subunit I cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I MHFCBNDO_00014 543734.LCABL_00150 1.74e-223 618.0 COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,4H9KF@91061|Bacilli,3F3ZH@33958|Lactobacillaceae 91061|Bacilli C Cytochrome bd terminal oxidase subunit II - - - - - - - - - - - - Cyt_bd_oxida_II MHFCBNDO_00015 543734.LCABL_00160 1.07e-35 121.0 2B5YU@1|root,31YUW@2|Bacteria,1U6T8@1239|Firmicutes,4IGM0@91061|Bacilli,3F8G7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00016 543734.LCABL_00170 9.41e-136 385.0 COG3548@1|root,COG3548@2|Bacteria,1VFW9@1239|Firmicutes,4HR1J@91061|Bacilli,3F4JD@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 MHFCBNDO_00019 543734.LCABL_00200 1.94e-181 506.0 COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,4HPR4@91061|Bacilli,3F5HF@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi MHFCBNDO_00023 543734.LCABL_00230 4.92e-201 567.0 COG3942@1|root,COG4942@1|root,COG3942@2|Bacteria,COG4942@2|Bacteria,1VCXB@1239|Firmicutes,4HMCB@91061|Bacilli,3F4ZY@33958|Lactobacillaceae 91061|Bacilli D CHAP domain p40 - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - CHAP MHFCBNDO_00024 543734.LCABL_00240 0.0 1580.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,3F4HF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease ylbB - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD MHFCBNDO_00025 543734.LCABL_00250 1.76e-165 462.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,3F3YU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_00026 543734.LCABL_00260 1.09e-125 358.0 COG1309@1|root,COG1309@2|Bacteria,1VI1M@1239|Firmicutes,4HPZV@91061|Bacilli,3F530@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator - - - - - - - - - - - - TetR_C_8,TetR_N MHFCBNDO_00027 543734.LCABL_00270 4.35e-197 545.0 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,3F3ZW@33958|Lactobacillaceae 91061|Bacilli G Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 MHFCBNDO_00028 543734.LCABL_00280 4.92e-65 198.0 29PRI@1|root,30APR@2|Bacteria,1U6YE@1239|Firmicutes,4IGSK@91061|Bacilli,3F8Q9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00031 543734.LCABL_00300 0.0 1392.0 COG3409@1|root,COG3409@2|Bacteria,1TPV1@1239|Firmicutes,4HCRA@91061|Bacilli,3F5J4@33958|Lactobacillaceae 91061|Bacilli M peptidoglycan-binding domain-containing protein ybfG - - - - - - - - - - - DUF1906,PG_binding_1 MHFCBNDO_00032 568703.LGG_00037 1.38e-158 447.0 COG0730@1|root,COG0730@2|Bacteria,1VR9G@1239|Firmicutes,4HV4W@91061|Bacilli,3F3TR@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE MHFCBNDO_00033 543734.LCABL_00320 2.33e-131 374.0 COG3548@1|root,COG3548@2|Bacteria,1V803@1239|Firmicutes,4IRHS@91061|Bacilli,3F6KM@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 MHFCBNDO_00034 543734.LCABL_00330 4.74e-211 583.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,3F4B8@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein - - - - - - - - - - - - CorA MHFCBNDO_00035 543734.LCABL_00340 3.84e-145 409.0 COG1309@1|root,COG1309@2|Bacteria,1V3R8@1239|Firmicutes,4HBEK@91061|Bacilli,3F75F@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N MHFCBNDO_00040 543734.LCABL_00360 4.77e-306 837.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp MHFCBNDO_00041 543734.LCABL_00370 1.85e-66 202.0 29Q91@1|root,30B85@2|Bacteria,1U7Q9@1239|Firmicutes,4IHMK@91061|Bacilli,3FA0E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00042 568703.LGG_00464 8.02e-228 626.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00043 1140001.I571_00212 7.5e-53 181.0 COG1396@1|root,COG1396@2|Bacteria,1UZI0@1239|Firmicutes,4HZ6P@91061|Bacilli,4AZI4@81852|Enterococcaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 MHFCBNDO_00044 543734.LCABL_00390 0.0 992.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 MHFCBNDO_00045 543734.LCABL_00400 6.62e-143 404.0 COG2364@1|root,COG2364@2|Bacteria,1VQW3@1239|Firmicutes,4HV4F@91061|Bacilli,3F64W@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - MHFCBNDO_00046 543734.LCABL_00430 8.78e-107 310.0 29QSZ@1|root,30BSU@2|Bacteria,1U8KU@1239|Firmicutes,4IIIV@91061|Bacilli,3FB3B@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00047 543734.LCABL_00440 3.26e-42 143.0 2BM2D@1|root,32FJC@2|Bacteria,1U7S8@1239|Firmicutes,4IHPK@91061|Bacilli,3FA3P@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00048 485916.Dtox_1835 1.09e-82 262.0 28J1N@1|root,2Z8YI@2|Bacteria,1TSQU@1239|Firmicutes,24F7K@186801|Clostridia 186801|Clostridia S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii MHFCBNDO_00049 945021.TEH_04260 1.23e-97 292.0 28KWY@1|root,2ZAD1@2|Bacteria,1VAA9@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - MHFCBNDO_00050 543734.LCABL_00470 1.08e-151 428.0 COG1296@1|root,COG1296@2|Bacteria,1U49T@1239|Firmicutes,4HDIJ@91061|Bacilli,3F45S@33958|Lactobacillaceae 91061|Bacilli E branched-chain amino acid azlC - - - - - - - - - - - AzlC MHFCBNDO_00051 543734.LCABL_00480 4.31e-65 199.0 COG4392@1|root,COG4392@2|Bacteria,1VH9Q@1239|Firmicutes,4HNDZ@91061|Bacilli,3F7IU@33958|Lactobacillaceae 91061|Bacilli S Branched-chain amino acid transport protein (AzlD) azlD - - - - - - - - - - - AzlD MHFCBNDO_00053 543734.LCABL_00510 4.53e-185 516.0 COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,4HPR4@91061|Bacilli,3F5HF@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi MHFCBNDO_00054 543734.LCABL_00520 6.9e-150 422.0 COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,3F6AY@33958|Lactobacillaceae 91061|Bacilli G KDPG and KHG aldolase eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase MHFCBNDO_00055 543734.LCABL_00540 9.03e-162 453.0 COG1802@1|root,COG1802@2|Bacteria,1V3SB@1239|Firmicutes,4HGG8@91061|Bacilli,3F69H@33958|Lactobacillaceae 91061|Bacilli K FCD domain kdgR - - - - - - - - - - - FCD,GntR MHFCBNDO_00057 543734.LCABL_00550 2.84e-73 219.0 2E9Y3@1|root,3343R@2|Bacteria,1VFF0@1239|Firmicutes,4HPUY@91061|Bacilli,3F8BC@33958|Lactobacillaceae 91061|Bacilli - - ps105 - - - - - - - - - - - - MHFCBNDO_00058 543734.LCABL_00560 1.13e-208 577.0 COG1396@1|root,COG1396@2|Bacteria,1UZI0@1239|Firmicutes,4I40C@91061|Bacilli,3F837@33958|Lactobacillaceae 91061|Bacilli K Transcriptional activator, Rgg GadR MutR family - - - - - - - - - - - - HTH_3 MHFCBNDO_00059 543734.LCABL_00570 0.0 984.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F46B@33958|Lactobacillaceae 91061|Bacilli V ABC-type multidrug transport system, ATPase and permease components - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran MHFCBNDO_00060 543734.LCABL_00580 1.8e-305 835.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 MHFCBNDO_00061 543734.LCABL_00590 3.19e-66 201.0 COG1476@1|root,COG1476@2|Bacteria,1W30D@1239|Firmicutes,4I0AB@91061|Bacilli,3F8T4@33958|Lactobacillaceae 91061|Bacilli K TRANSCRIPTIONal - - - - - - - - - - - - - MHFCBNDO_00062 543734.LCABL_00600 0.0 1445.0 COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4HBM6@91061|Bacilli,3FCCY@33958|Lactobacillaceae 91061|Bacilli S MMPL family ydgH - - ko:K06994 - - - - ko00000 - - - MMPL MHFCBNDO_00063 543734.LCABL_00610 2.34e-140 396.0 COG1309@1|root,COG1309@2|Bacteria,1V95E@1239|Firmicutes,4HH9M@91061|Bacilli,3F6ZH@33958|Lactobacillaceae 91061|Bacilli K Tetracycline repressor, C-terminal all-alpha domain - - - ko:K22106 - - - - ko00000,ko03000 - - - TetR_C_10,TetR_N MHFCBNDO_00065 543734.LCABL_00630 3.93e-142 402.0 COG1174@1|root,COG1174@2|Bacteria,1TQ5C@1239|Firmicutes,4HAVM@91061|Bacilli,3F51B@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component opuCD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iYO844.BSU33800 BPD_transp_1 MHFCBNDO_00066 543734.LCABL_00640 3.55e-222 612.0 COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HARV@91061|Bacilli,3F420@33958|Lactobacillaceae 91061|Bacilli M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) opuCC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12835 OpuAC MHFCBNDO_00067 543734.LCABL_00650 2.28e-136 387.0 COG1174@1|root,COG1174@2|Bacteria,1TSX8@1239|Firmicutes,4HC1D@91061|Bacilli,3F4EM@33958|Lactobacillaceae 91061|Bacilli E ABC transporter permease opuCB - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 MHFCBNDO_00068 543734.LCABL_00660 1.72e-285 781.0 COG1125@1|root,COG2905@1|root,COG1125@2|Bacteria,COG2905@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,3F55H@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein opuCA - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12845,iYO844.BSU33730 ABC_tran,CBS MHFCBNDO_00069 1165841.SULAR_03382 0.000666 46.6 COG1266@1|root,COG1266@2|Bacteria,1ND7U@1224|Proteobacteria 1224|Proteobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi MHFCBNDO_00071 543734.LCABL_00670 0.0 1115.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4T3@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase MHFCBNDO_00072 543734.LCABL_00680 3.61e-46 148.0 COG2608@1|root,COG2608@2|Bacteria,1VFJ8@1239|Firmicutes,4HNY2@91061|Bacilli,3F830@33958|Lactobacillaceae 91061|Bacilli P Heavy-metal-associated domain copZ - - - - - - - - - - - HMA MHFCBNDO_00073 543734.LCABL_00700 2.73e-127 363.0 COG0783@1|root,COG0783@2|Bacteria,1VB1X@1239|Firmicutes,4HMJG@91061|Bacilli,3F4SN@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Dps family dpsB - - - - - - - - - - - Ferritin MHFCBNDO_00074 543734.LCABL_00710 1.23e-149 421.0 COG0664@1|root,COG0664@2|Bacteria,1UZT0@1239|Firmicutes,4HFR2@91061|Bacilli,3FBKF@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, cAMP Regulatory protein flp - - ko:K21562 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding MHFCBNDO_00075 543734.LCABL_00720 1.38e-182 508.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,3F50S@33958|Lactobacillaceae 91061|Bacilli E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA MHFCBNDO_00076 543734.LCABL_00730 3.37e-291 795.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,3F4DT@33958|Lactobacillaceae 91061|Bacilli E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22640 PALP MHFCBNDO_00077 543734.LCABL_00740 2.62e-132 376.0 COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HN68@91061|Bacilli,3F4B6@33958|Lactobacillaceae 91061|Bacilli E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI MHFCBNDO_00078 543734.LCABL_00750 8.57e-175 488.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HDZQ@91061|Bacilli,3F5AK@33958|Lactobacillaceae 91061|Bacilli E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS MHFCBNDO_00079 543734.LCABL_00760 4.15e-234 645.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,3F50X@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 MHFCBNDO_00080 543734.LCABL_00830 1.59e-266 730.0 2C353@1|root,309Q7@2|Bacteria,1U5H7@1239|Firmicutes,4IF82@91061|Bacilli,3F5XZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00081 543734.LCABL_00840 0.0 1068.0 COG0477@1|root,COG2211@1|root,COG0477@2|Bacteria,COG2211@2|Bacteria,1TPV3@1239|Firmicutes,4HCJN@91061|Bacilli,3F5DE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 MHFCBNDO_00082 543734.LCABL_00850 7.06e-138 389.0 COG1309@1|root,COG1309@2|Bacteria,1V9ST@1239|Firmicutes,4HP6S@91061|Bacilli,3F5J7@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N MHFCBNDO_00083 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00085 543734.LCABL_00860 1.6e-160 451.0 2BJ44@1|root,32DD4@2|Bacteria,1U7J0@1239|Firmicutes,4IHFT@91061|Bacilli,3F9SG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00086 543734.LCABL_00870 7.33e-272 746.0 COG1277@1|root,COG1277@2|Bacteria,1VKEJ@1239|Firmicutes,4HS6Y@91061|Bacilli,3F7SD@33958|Lactobacillaceae 91061|Bacilli S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - MHFCBNDO_00087 543734.LCABL_00880 8.73e-206 570.0 2AD8Y@1|root,312XZ@2|Bacteria,1U71Z@1239|Firmicutes,4IGWF@91061|Bacilli,3F8VJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00088 543734.LCABL_00890 1.28e-135 387.0 COG1131@1|root,COG1131@2|Bacteria,1UQMC@1239|Firmicutes,4HE32@91061|Bacilli,3F6CK@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_00091 543734.LCABL_00900 7.06e-81 239.0 2DXZ0@1|root,3478Y@2|Bacteria,1W12R@1239|Firmicutes,4HYFZ@91061|Bacilli,3FC0I@33958|Lactobacillaceae 91061|Bacilli S PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin MHFCBNDO_00093 543734.LCABL_00960 2.21e-179 499.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,3F3MA@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N MHFCBNDO_00094 543734.LCABL_00970 6.02e-216 596.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,3F4UH@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS MHFCBNDO_00095 543734.LCABL_00980 7.47e-281 767.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,3F419@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 MHFCBNDO_00096 543734.LCABL_00990 4.4e-116 338.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,3F3U0@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep MHFCBNDO_00097 543734.LCABL_01000 0.0 885.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,3F3VJ@33958|Lactobacillaceae 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC MHFCBNDO_00098 543734.LCABL_01010 0.0 897.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,3F48V@33958|Lactobacillaceae 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 MHFCBNDO_00099 543734.LCABL_01020 2.33e-237 653.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,3F4F7@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase MHFCBNDO_00100 543734.LCABL_01030 5.59e-249 684.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,3F4S9@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC MHFCBNDO_00101 543734.LCABL_01040 5.73e-82 243.0 29PM4@1|root,30AVT@2|Bacteria,1U75Z@1239|Firmicutes,4IH0M@91061|Bacilli,3F90S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00102 543734.LCABL_01050 1.35e-97 283.0 COG0494@1|root,COG0494@2|Bacteria,1VK3S@1239|Firmicutes,4IHJ0@91061|Bacilli,3F9X5@33958|Lactobacillaceae 91061|Bacilli L NUDIX domain - - - - - - - - - - - - NUDIX MHFCBNDO_00103 543734.LCABL_01060 1.48e-189 528.0 COG0697@1|root,COG0697@2|Bacteria,1V86F@1239|Firmicutes,4HJWZ@91061|Bacilli,3F4CV@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA MHFCBNDO_00104 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00105 543734.LCABL_01070 3.91e-124 354.0 29XQD@1|root,30JG1@2|Bacteria,1TVFA@1239|Firmicutes,4I1PS@91061|Bacilli,3FAZJ@33958|Lactobacillaceae 91061|Bacilli S Phospholipase A2 - - - - - - - - - - - - Phospholip_A2_1 MHFCBNDO_00107 543734.LCABL_01090 0.0 1283.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,3F3TY@33958|Lactobacillaceae 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 MHFCBNDO_00108 543734.LCABL_01100 1.35e-97 284.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,3F68P@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N MHFCBNDO_00109 543734.LCABL_01110 0.0 868.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,3F4MW@33958|Lactobacillaceae 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C MHFCBNDO_00110 543734.LCABL_01120 4.65e-277 758.0 2CC2J@1|root,309K5@2|Bacteria,1U598@1239|Firmicutes,4IF0I@91061|Bacilli,3F58S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00111 568703.LGG_00125 0.0 993.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts32BC - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC MHFCBNDO_00112 1423732.BALS01000041_gene2564 1.01e-165 469.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,3F4T1@33958|Lactobacillaceae 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 MHFCBNDO_00113 568703.LGG_00128 4.06e-153 436.0 COG1737@1|root,COG1737@2|Bacteria,1TPIX@1239|Firmicutes,4HBJA@91061|Bacilli,3F5WQ@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family yleF - - - - - - - - - - - HTH_6,SIS MHFCBNDO_00114 568703.LGG_00129 5.32e-117 337.0 COG1309@1|root,COG1309@2|Bacteria,1V9XI@1239|Firmicutes,4HJ7Q@91061|Bacilli,3F77G@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator C-terminal region - - - - - - - - - - - - TetR_C_8,TetR_N MHFCBNDO_00115 568703.LGG_00130 1.19e-143 407.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,3F3YU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_00116 568703.LGG_00131 0.0 1289.0 COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,3F4HF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease ylbB - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD MHFCBNDO_00117 568703.LGG_00132 2.01e-214 596.0 COG2159@1|root,COG2159@2|Bacteria,1TRAY@1239|Firmicutes,4HFH2@91061|Bacilli,3F485@33958|Lactobacillaceae 91061|Bacilli S Amidohydrolase - - 4.1.1.52 ko:K22213 - - - - ko00000,ko01000 - - - Amidohydro_2 MHFCBNDO_00118 543734.LCABL_01130 9.64e-317 862.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,3F3RQ@33958|Lactobacillaceae 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt MHFCBNDO_00119 543734.LCABL_01140 0.0 1139.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4T3@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase MHFCBNDO_00120 543734.LCABL_01150 5.08e-74 222.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HFYU@91061|Bacilli,3FB53@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor cadC5 - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_5 MHFCBNDO_00121 543734.LCABL_01160 0.0 1471.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HVA4@91061|Bacilli,3F55J@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus - - 3.6.3.6 ko:K01535 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.3 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase MHFCBNDO_00122 543734.LCABL_01170 6.67e-204 565.0 COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,4HBNZ@91061|Bacilli,3F4XG@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain lysR5 - - - - - - - - - - - HTH_1,LysR_substrate MHFCBNDO_00123 543734.LCABL_01180 1.19e-256 705.0 COG1476@1|root,COG1476@2|Bacteria,1TNYC@1239|Firmicutes,4HF5V@91061|Bacilli,3F58D@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 MHFCBNDO_00124 543734.LCABL_01190 7.81e-46 147.0 2E3AZ@1|root,32YAF@2|Bacteria,1VF37@1239|Firmicutes,4HP14@91061|Bacilli,3F8CH@33958|Lactobacillaceae 91061|Bacilli S Phospholipase_D-nuclease N-terminal - - - - - - - - - - - - PLDc_N MHFCBNDO_00125 543734.LCABL_01200 2.64e-214 592.0 COG1131@1|root,COG1131@2|Bacteria,1TQEV@1239|Firmicutes,4HBHF@91061|Bacilli,3F612@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yxlF - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 MHFCBNDO_00126 543734.LCABL_01210 3.78e-170 476.0 COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,4HIS1@91061|Bacilli,3F5JZ@33958|Lactobacillaceae 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 MHFCBNDO_00127 543734.LCABL_01220 0.0 1481.0 COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,4HBIY@91061|Bacilli,3F435@33958|Lactobacillaceae 91061|Bacilli F Ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD MHFCBNDO_00129 543734.LCABL_01240 2.59e-129 369.0 COG1476@1|root,COG1476@2|Bacteria,1V6QF@1239|Firmicutes,4HIIT@91061|Bacilli,3F7M5@33958|Lactobacillaceae 91061|Bacilli K Bacteriophage CI repressor helix-turn-helix domain - - - - - - - - - - - - DUF3955,HTH_3 MHFCBNDO_00130 543734.LCABL_01250 0.0 896.0 2DBW0@1|root,2ZBE0@2|Bacteria,1V57P@1239|Firmicutes,4HH8K@91061|Bacilli,3F5BJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - PA MHFCBNDO_00131 543734.LCABL_01260 1.83e-182 507.0 COG0639@1|root,COG0639@2|Bacteria,1V45T@1239|Firmicutes,4HHSG@91061|Bacilli,3F6PM@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 MHFCBNDO_00132 543734.LCABL_01270 2.41e-118 349.0 COG0277@1|root,COG0277@2|Bacteria,1U53V@1239|Firmicutes,4HDF7@91061|Bacilli 91061|Bacilli C COG0277 FAD FMN-containing dehydrogenases yvdP - - - - - - - - - - - BBE,FAD_binding_4 MHFCBNDO_00133 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00134 543734.LCABL_01270 2.83e-158 453.0 COG0277@1|root,COG0277@2|Bacteria,1U53V@1239|Firmicutes,4HDF7@91061|Bacilli 91061|Bacilli C COG0277 FAD FMN-containing dehydrogenases yvdP - - - - - - - - - - - BBE,FAD_binding_4 MHFCBNDO_00136 543734.LCABL_01300 5.67e-49 157.0 2ENBH@1|root,33FZ4@2|Bacteria,1VM60@1239|Firmicutes,4HREG@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00137 543734.LCABL_01310 2.66e-57 178.0 COG3877@1|root,COG3877@2|Bacteria,1VGSH@1239|Firmicutes,4HQ68@91061|Bacilli,3F84H@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2089) - - - - - - - - - - - - DUF2089 MHFCBNDO_00138 543734.LCABL_01320 3.7e-234 644.0 COG0671@1|root,COG0671@2|Bacteria,1V7AD@1239|Firmicutes,4HJB7@91061|Bacilli,3F4Q4@33958|Lactobacillaceae 91061|Bacilli I PAP2 superfamily yveB - - - - - - - - - - - PAP2 MHFCBNDO_00139 543734.LCABL_01330 2.35e-269 736.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HDUZ@91061|Bacilli,3F3NK@33958|Lactobacillaceae 91061|Bacilli V LD-carboxypeptidase mccF - - - - - - - - - - - Peptidase_S66 MHFCBNDO_00140 543734.LCABL_01340 6.55e-57 176.0 29QF0@1|root,30BEB@2|Bacteria,1U7ZU@1239|Firmicutes,4IHX8@91061|Bacilli,3FAD7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00141 543734.LCABL_01350 2.61e-261 715.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,3F41Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N MHFCBNDO_00142 543734.LCABL_01360 3.37e-115 330.0 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,3F6RF@33958|Lactobacillaceae 91061|Bacilli L Methyltransferase adaB GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,Methyltransf_1N MHFCBNDO_00143 543734.LCABL_01370 1.66e-245 673.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HCIS@91061|Bacilli,3F4US@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhD3 - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C MHFCBNDO_00144 543734.LCABL_01380 9.97e-59 182.0 298HG@1|root,2ZKVW@2|Bacteria,1W538@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - MHFCBNDO_00145 543734.LCABL_01390 1.85e-110 318.0 COG1846@1|root,COG1846@2|Bacteria,1W4X8@1239|Firmicutes,4I172@91061|Bacilli,3F8CB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - MarR MHFCBNDO_00146 543734.LCABL_01400 4.54e-204 568.0 COG0604@1|root,COG0604@2|Bacteria,1V2UJ@1239|Firmicutes,4HG2A@91061|Bacilli,3F52N@33958|Lactobacillaceae 91061|Bacilli C alcohol dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_zinc_N MHFCBNDO_00147 543734.LCABL_01410 3.12e-70 213.0 COG3759@1|root,COG3759@2|Bacteria,1VAVU@1239|Firmicutes,4HQHN@91061|Bacilli,3F7NA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1304) - - - ko:K08987 - - - - ko00000 - - - DUF1304 MHFCBNDO_00148 543734.LCABL_01420 1.7e-72 218.0 2EGA1@1|root,33A1U@2|Bacteria,1VPXU@1239|Firmicutes,4HS3Y@91061|Bacilli,3F7WK@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1516) - - - - - - - - - - - - DUF1516 MHFCBNDO_00149 543734.LCABL_01430 0.0 885.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,3F44D@33958|Lactobacillaceae 91061|Bacilli S permease XK27_07275 - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease MHFCBNDO_00150 568703.LGG_00169 1.2e-61 190.0 COG1416@1|root,COG1416@2|Bacteria,1VEYT@1239|Firmicutes,4HQQN@91061|Bacilli,3FBBQ@33958|Lactobacillaceae 91061|Bacilli S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE MHFCBNDO_00152 568703.LGG_00172 4.2e-130 374.0 COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HBZ6@91061|Bacilli,3FC3F@33958|Lactobacillaceae 91061|Bacilli P ATPases associated with a variety of cellular activities ytlC - 3.6.3.36 ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 M00188,M00435,M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.2,3.A.1.17.4 - - ABC_tran MHFCBNDO_00153 568703.LGG_00173 4.07e-150 432.0 COG4521@1|root,COG4521@2|Bacteria,1TSJU@1239|Firmicutes,4HFCZ@91061|Bacilli 91061|Bacilli P NMT1-like family - - - ko:K15551 ko00920,ko02010,map00920,map02010 M00435 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.1,3.A.1.17.4 - - NMT1,NMT1_2,OpuAC MHFCBNDO_00154 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00155 568703.LGG_00174 3.21e-89 270.0 COG0600@1|root,COG0600@2|Bacteria,1U217@1239|Firmicutes,4HCS9@91061|Bacilli,3FBIE@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02050,ko:K15552 ko00920,ko02010,map00920,map02010 M00188,M00435 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4 - - BPD_transp_1 MHFCBNDO_00156 568703.LGG_00175 0.0 957.0 COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,3FBSF@33958|Lactobacillaceae 91061|Bacilli P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,Rhodanese MHFCBNDO_00157 568703.LGG_00176 1.86e-252 699.0 COG2391@1|root,COG2391@2|Bacteria,1TSNG@1239|Firmicutes,4HCH9@91061|Bacilli,3F7RB@33958|Lactobacillaceae 91061|Bacilli S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp MHFCBNDO_00158 568703.LGG_00177 2.61e-124 364.0 COG0583@1|root,COG0583@2|Bacteria,1U35Y@1239|Firmicutes,4HCXK@91061|Bacilli,3FBI9@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate MHFCBNDO_00160 568703.LGG_00178 1.01e-228 630.0 COG0346@1|root,COG0346@2|Bacteria,1TP7I@1239|Firmicutes,4H9ND@91061|Bacilli,3F4PB@33958|Lactobacillaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily mhqA - - ko:K15975 - - - - ko00000 - - - Glyoxalase MHFCBNDO_00161 568703.LGG_00179 6.64e-39 132.0 29Q9W@1|root,30B8Z@2|Bacteria,1U7RE@1239|Firmicutes,4IHNS@91061|Bacilli,3FA2D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00162 543734.LCABL_01470 1.22e-133 379.0 COG1670@1|root,COG1670@2|Bacteria,1VCN3@1239|Firmicutes,4HKNF@91061|Bacilli,3F7GP@33958|Lactobacillaceae 91061|Bacilli J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins yoaA - - - - - - - - - - - Acetyltransf_3 MHFCBNDO_00163 543734.LCABL_01490 0.0 1193.0 2F70X@1|root,33ZGK@2|Bacteria,1VXAH@1239|Firmicutes,4HXTD@91061|Bacilli,3F9HI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00165 543734.LCABL_01520 2e-167 469.0 29WH0@1|root,30I33@2|Bacteria,1U57C@1239|Firmicutes,4IEYT@91061|Bacilli,3F511@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL MHFCBNDO_00166 543734.LCABL_01530 2.04e-171 479.0 COG4886@1|root,COG4886@2|Bacteria,1V9D9@1239|Firmicutes,4HJPY@91061|Bacilli,3F7MH@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL MHFCBNDO_00167 543734.LCABL_01540 8.11e-241 664.0 COG4072@1|root,COG4072@2|Bacteria,1VCXS@1239|Firmicutes,4HKJG@91061|Bacilli,3F5HA@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein ynjC - - - - - - - - - - - DUF3324,DUF916 MHFCBNDO_00169 543734.LCABL_01560 0.0 952.0 COG3711@1|root,COG3711@2|Bacteria,1VBUE@1239|Firmicutes,4HN8V@91061|Bacilli,3FBAD@33958|Lactobacillaceae 91061|Bacilli L Mga helix-turn-helix domain - - - - - - - - - - - - Mga MHFCBNDO_00170 543734.LCABL_01570 1.36e-221 612.0 COG3152@1|root,COG3152@2|Bacteria,1VP5A@1239|Firmicutes,4IFSK@91061|Bacilli,3F6XM@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 MHFCBNDO_00171 543734.LCABL_01580 1.1e-76 228.0 2C1B3@1|root,302T3@2|Bacteria,1U6JW@1239|Firmicutes,4IGCF@91061|Bacilli,3F821@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00172 543734.LCABL_01590 0.0 880.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3NB@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N MHFCBNDO_00173 543734.LCABL_01600 1.07e-282 773.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase MHFCBNDO_00174 543734.LCABL_01610 4.73e-204 563.0 COG0639@1|root,COG0639@2|Bacteria,1V1HN@1239|Firmicutes,4HHQ3@91061|Bacilli,3FCCD@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase superfamily domain pphA - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos MHFCBNDO_00175 543734.LCABL_01620 5.47e-178 495.0 COG2231@1|root,COG2231@2|Bacteria,1V4SG@1239|Firmicutes,4HI5U@91061|Bacilli,3F62T@33958|Lactobacillaceae 91061|Bacilli L Base excision DNA repair protein, HhH-GPD family - - - ko:K07457 - - - - ko00000 - - - HhH-GPD MHFCBNDO_00176 543734.LCABL_01630 4.22e-60 185.0 COG0011@1|root,COG0011@2|Bacteria,1VC4R@1239|Firmicutes,4HSQA@91061|Bacilli,3F7GK@33958|Lactobacillaceae 91061|Bacilli S Thiamine-binding protein - - - - - - - - - - - - Thiamine_BP MHFCBNDO_00177 543734.LCABL_01640 0.0 1003.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,3F3Y3@33958|Lactobacillaceae 91061|Bacilli V domain protein yhgE - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 MHFCBNDO_00178 543734.LCABL_01650 4.77e-130 369.0 COG1309@1|root,COG1309@2|Bacteria,1V1DM@1239|Firmicutes,4HG0Y@91061|Bacilli,3F5CS@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family yobS GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N,WHG MHFCBNDO_00179 543734.LCABL_01660 0.0 906.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator bmr3 - - - - - - - - - - - MFS_1 MHFCBNDO_00181 543734.LCABL_01680 0.0 1645.0 COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,4HC2J@91061|Bacilli,3F3TZ@33958|Lactobacillaceae 91061|Bacilli G Phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N MHFCBNDO_00182 543734.LCABL_01690 0.0 1047.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 MHFCBNDO_00183 1423816.BACQ01000030_gene1065 6.63e-128 369.0 2BFQS@1|root,329JG@2|Bacteria,1TZIV@1239|Firmicutes,4IGKR@91061|Bacilli,3F8FT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00184 1423732.BALS01000077_gene2126 2.97e-66 211.0 2AHJ7@1|root,317WU@2|Bacteria,1U7P7@1239|Firmicutes,4IHKH@91061|Bacilli,3F9Z1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00185 568703.LGG_00204 1.37e-91 276.0 29Q10@1|root,30AZH@2|Bacteria,1U7B5@1239|Firmicutes,4IH65@91061|Bacilli,3F994@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00186 1423816.BACQ01000030_gene1062 6.97e-115 334.0 COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,4HDRD@91061|Bacilli,3FC3S@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_00187 1423816.BACQ01000030_gene1061 7.76e-56 179.0 29Q9A@1|root,30B8E@2|Bacteria,1U7QJ@1239|Firmicutes,4IHMW@91061|Bacilli,3FA0T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00188 543734.LCABL_01720 4.15e-103 298.0 2BFZ1@1|root,329UX@2|Bacteria,1W1ZW@1239|Firmicutes,4I0E0@91061|Bacilli 91061|Bacilli S NUDIX domain - - - - - - - - - - - - NUDIX MHFCBNDO_00189 543734.LCABL_01730 7.09e-274 749.0 COG1537@1|root,COG1537@2|Bacteria,1UPQ9@1239|Firmicutes,4IV8X@91061|Bacilli,3FC0K@33958|Lactobacillaceae 91061|Bacilli S nuclear-transcribed mRNA catabolic process, no-go decay - - - - - - - - - - - - - MHFCBNDO_00190 1423816.BACQ01000030_gene1058 3.37e-285 790.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F6VM@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran MHFCBNDO_00191 1423732.BALS01000042_gene2692 2.53e-141 407.0 COG1396@1|root,COG1396@2|Bacteria,1VD8E@1239|Firmicutes,4HMD2@91061|Bacilli,3F8P8@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins ywdE - - ko:K20375 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 MHFCBNDO_00192 543734.LCABL_01740 0.0 1231.0 COG4529@1|root,COG4529@2|Bacteria,1UZ38@1239|Firmicutes,4HDXC@91061|Bacilli,3F4ZH@33958|Lactobacillaceae 91061|Bacilli S FAD-NAD(P)-binding fnq20 - - - - - - - - - - - NAD_binding_9 MHFCBNDO_00193 543734.LCABL_01750 0.0 902.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase nox - 1.6.3.4 ko:K17869 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim MHFCBNDO_00194 543734.LCABL_01760 6.18e-150 421.0 29DQI@1|root,300NC@2|Bacteria,1U55V@1239|Firmicutes,4IEX6@91061|Bacilli,3F4UQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00195 543734.LCABL_01770 6.38e-282 774.0 COG1512@1|root,COG1512@2|Bacteria,1VHE2@1239|Firmicutes,4HJHN@91061|Bacilli,3F75Q@33958|Lactobacillaceae 91061|Bacilli S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase MHFCBNDO_00196 543734.LCABL_01780 1.02e-176 495.0 COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,4HCYJ@91061|Bacilli,3FCAW@33958|Lactobacillaceae 91061|Bacilli S Sulfite exporter TauE/SafE yunE - - ko:K07090 - - - - ko00000 - - - TauE MHFCBNDO_00197 543734.LCABL_01790 6.45e-74 222.0 COG4272@1|root,COG4272@2|Bacteria,1VAPQ@1239|Firmicutes,4IRG9@91061|Bacilli,3FBP6@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1634) ywjH - - - - - - - - - - - DUF1634 MHFCBNDO_00198 1423790.BN53_05765 1.47e-07 50.4 29PI4@1|root,30AG9@2|Bacteria,1U6MC@1239|Firmicutes,4IGE7@91061|Bacilli,3F858@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00199 543734.LCABL_01810 5.12e-117 335.0 29QKG@1|root,30BK4@2|Bacteria,1U898@1239|Firmicutes,4II73@91061|Bacilli,3FAQ9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00200 568703.LGG_00220 4.85e-65 198.0 29Q8B@1|root,30B7C@2|Bacteria,1U7P0@1239|Firmicutes,4IHK9@91061|Bacilli,3F9YT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00201 543734.LCABL_01830 1.63e-109 315.0 COG0716@1|root,COG0716@2|Bacteria,1U7EW@1239|Firmicutes,4IHAT@91061|Bacilli,3F9HX@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin - - - - - - - - - - - - Flavodoxin_1 MHFCBNDO_00202 1423816.BACQ01000030_gene1046 5.54e-50 158.0 2930D@1|root,3270J@2|Bacteria,1USWD@1239|Firmicutes,4IG6X@91061|Bacilli,3F7S4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00203 543734.LCABL_01850 2.82e-36 122.0 29QNT@1|root,30BNF@2|Bacteria,1U8D5@1239|Firmicutes,4IIB4@91061|Bacilli,3FAUS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00204 543734.LCABL_01860 2.86e-219 606.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,3F4Z6@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C MHFCBNDO_00205 543734.LCABL_01870 2.27e-94 275.0 COG3576@1|root,COG3576@2|Bacteria,1V4U5@1239|Firmicutes,4HX4S@91061|Bacilli,3FBB6@33958|Lactobacillaceae 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx MHFCBNDO_00206 543734.LCABL_01880 1.93e-52 165.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc MHFCBNDO_00207 543734.LCABL_01890 1.16e-112 325.0 COG1302@1|root,COG1302@2|Bacteria,1VN34@1239|Firmicutes,4HRAM@91061|Bacilli,3F8AH@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria - - - - - - - - - - - - - MHFCBNDO_00208 568703.LGG_00229 4.15e-34 117.0 29QCQ@1|root,30BBZ@2|Bacteria,1U7VV@1239|Firmicutes,4IHT8@91061|Bacilli,3FA8J@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00209 543734.LCABL_01910 8.12e-90 263.0 COG1302@1|root,COG1302@2|Bacteria,1VCNX@1239|Firmicutes,4HKR6@91061|Bacilli,3FB58@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function asp23 - - - - - - - - - - - Asp23 MHFCBNDO_00210 543734.LCABL_01920 1.97e-92 270.0 COG1302@1|root,COG1302@2|Bacteria,1VJRA@1239|Firmicutes,4HXJN@91061|Bacilli,3F692@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function asp2 - - - - - - - - - - - Asp23 MHFCBNDO_00211 543734.LCABL_01930 2.66e-147 416.0 COG3819@1|root,COG3819@2|Bacteria,1TT00@1239|Firmicutes,4HE38@91061|Bacilli,3F538@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF969) - - - - - - - - - - - - DUF969 MHFCBNDO_00212 543734.LCABL_01940 1.42e-195 545.0 COG3817@1|root,COG3817@2|Bacteria,1TQ17@1239|Firmicutes,4HAJT@91061|Bacilli,3F5QJ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF979) - - - - - - - - - - - - DUF979 MHFCBNDO_00213 543734.LCABL_01950 6.93e-154 432.0 COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,4HCIJ@91061|Bacilli,3F46I@33958|Lactobacillaceae 91061|Bacilli O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 MHFCBNDO_00214 543734.LCABL_01960 6.15e-139 393.0 COG2085@1|root,COG2085@2|Bacteria,1VW6H@1239|Firmicutes,4HWI6@91061|Bacilli,3F6QU@33958|Lactobacillaceae 91061|Bacilli S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored MHFCBNDO_00215 543734.LCABL_01970 1.35e-164 459.0 COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,4HD1P@91061|Bacilli,3F4CH@33958|Lactobacillaceae 91061|Bacilli S glutamine amidotransferase cobQ - - ko:K07009 - - - - ko00000 - - - GATase_3 MHFCBNDO_00216 543734.LCABL_01980 4.01e-87 256.0 29PCH@1|root,30AAR@2|Bacteria,1U6EK@1239|Firmicutes,4IG6D@91061|Bacilli,3F7R0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00217 543734.LCABL_01990 2.27e-167 468.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,3F3ZX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB MHFCBNDO_00218 543734.LCABL_02000 7.98e-188 523.0 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,3F4RU@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc MHFCBNDO_00219 543734.LCABL_02010 1.49e-177 495.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,3F4AE@33958|Lactobacillaceae 91061|Bacilli D Sporulation initiation inhibitor soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 MHFCBNDO_00220 543734.LCABL_02020 1.11e-201 559.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,3F47R@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc MHFCBNDO_00221 543734.LCABL_02030 3.26e-40 132.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli,3F823@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF951) yyzM - - - - - - - - - - - DUF951 MHFCBNDO_00222 543734.LCABL_02040 9.76e-237 653.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,3F3TK@33958|Lactobacillaceae 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C MHFCBNDO_00223 543734.LCABL_02050 8.29e-168 472.0 COG4858@1|root,COG4858@2|Bacteria,1VF5N@1239|Firmicutes,4HH7B@91061|Bacilli,3F4JS@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1129) - - - - - - - - - - - - DUF1129 MHFCBNDO_00224 543734.LCABL_02060 0.0 952.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,3F3XN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH MHFCBNDO_00225 543734.LCABL_02070 2.05e-156 439.0 2F4SR@1|root,33XFD@2|Bacteria,1VW0F@1239|Firmicutes,4HWCG@91061|Bacilli,3F6TR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00226 543734.LCABL_02080 1.68e-156 439.0 COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,3F3Y0@33958|Lactobacillaceae 91061|Bacilli K response regulator vanR - - - - - - - - - - - Response_reg,Trans_reg_C MHFCBNDO_00227 543734.LCABL_02090 2.81e-278 761.0 COG5002@1|root,COG5002@2|Bacteria,1TPB6@1239|Firmicutes,4HARU@91061|Bacilli,3F479@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase hpk31 - - - - - - - - - - - HATPase_c,HisKA MHFCBNDO_00228 543734.LCABL_02100 1.85e-301 823.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,3F43S@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 MHFCBNDO_00229 543734.LCABL_02110 1.02e-103 300.0 COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,4HW8H@91061|Bacilli,3F6ZK@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N MHFCBNDO_00230 543734.LCABL_02120 0.0 1006.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,3F3UE@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 - R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M MHFCBNDO_00231 543734.LCABL_02130 2.23e-181 504.0 COG1794@1|root,COG1794@2|Bacteria,1V34N@1239|Firmicutes,4HG8W@91061|Bacilli,3F3XZ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the aspartate glutamate racemases family racD - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race MHFCBNDO_00232 543734.LCABL_02140 1.36e-209 578.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,3F3PW@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase yvgN - - - - - - - - - - - Aldo_ket_red MHFCBNDO_00233 543734.LCABL_02150 7.14e-187 520.0 COG1349@1|root,COG1349@2|Bacteria,1TTGR@1239|Firmicutes,4HEVD@91061|Bacilli 91061|Bacilli K COG1349 Transcriptional regulators of sugar metabolism iolR - - ko:K06608,ko:K11534 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR MHFCBNDO_00234 543734.LCABL_02160 0.0 917.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,3F3ZS@33958|Lactobacillaceae 91061|Bacilli EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family iolT GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K06609 - - - - ko00000,ko02000 2.A.1.1.26 - - Sugar_tr MHFCBNDO_00235 543734.LCABL_02170 0.0 974.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family iolA GO:0003674,GO:0003824,GO:0004491,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh MHFCBNDO_00236 543734.LCABL_02180 8.47e-201 555.0 COG3718@1|root,COG3718@2|Bacteria,1TR6M@1239|Firmicutes,4HCDY@91061|Bacilli,3F4TI@33958|Lactobacillaceae 91061|Bacilli G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) iolB - 5.3.1.30 ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08503 RC00541 ko00000,ko00001,ko01000 - - - KduI MHFCBNDO_00237 543734.LCABL_02190 6.58e-228 628.0 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,4HB78@91061|Bacilli,3FC23@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) iolC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044424,GO:0044464,GO:0046434,GO:0046835,GO:0071704,GO:1901575 2.7.1.92 ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R05661 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU39740 PfkB MHFCBNDO_00238 543734.LCABL_02200 0.0 1268.0 COG3962@1|root,COG3962@2|Bacteria,1UI18@1239|Firmicutes,4HCPP@91061|Bacilli,3F9EH@33958|Lactobacillaceae 91061|Bacilli E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) iolD GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0071704,GO:1901575 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08603 RC02331 ko00000,ko00001,ko01000 - - iYO844.BSU39730 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N MHFCBNDO_00239 543734.LCABL_02210 9.62e-247 677.0 COG0673@1|root,COG0673@2|Bacteria,1U4A4@1239|Firmicutes,4HBTG@91061|Bacilli,3F94F@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold - - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA MHFCBNDO_00240 543734.LCABL_02220 3.37e-249 684.0 COG0673@1|root,COG0673@2|Bacteria,1TQJX@1239|Firmicutes,4HAJ8@91061|Bacilli,3F5FQ@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain iolG2 - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C MHFCBNDO_00241 543734.LCABL_02230 1.27e-223 615.0 COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,4HCIM@91061|Bacilli,3F5FP@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) iolE - 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 - - - AP_endonuc_2 MHFCBNDO_00242 543734.LCABL_02240 4.69e-203 562.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,3F9NW@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II iolJ - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39670 F_bP_aldolase MHFCBNDO_00243 543734.LCABL_02250 8.67e-88 258.0 COG1942@1|root,COG1942@2|Bacteria,1V3SS@1239|Firmicutes,4HI9G@91061|Bacilli,3F6UD@33958|Lactobacillaceae 91061|Bacilli S Tautomerase enzyme yodA - - - - - - - - - - - Tautomerase_2 MHFCBNDO_00244 543734.LCABL_02260 1.8e-186 520.0 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,3F42G@33958|Lactobacillaceae 91061|Bacilli K rpiR family gntR - - - - - - - - - - - HTH_6,SIS MHFCBNDO_00245 543734.LCABL_02270 5.16e-217 598.0 COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,3F4X7@33958|Lactobacillaceae 91061|Bacilli G Dehydrogenase gntZ - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 MHFCBNDO_00246 543734.LCABL_02280 0.0 1047.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,3F4R2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N MHFCBNDO_00247 543734.LCABL_02290 3.1e-268 741.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,3F3V0@33958|Lactobacillaceae 91061|Bacilli EG Gluconate gntP - - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease MHFCBNDO_00248 543734.LCABL_02390 3.74e-75 224.0 2CICD@1|root,3462T@2|Bacteria,1VZWZ@1239|Firmicutes,4HY4B@91061|Bacilli,3F6T8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00249 543734.LCABL_02400 5.86e-167 467.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,3F49M@33958|Lactobacillaceae 91061|Bacilli P ABC transporter adcC - - ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 M00242,M00244,M00319 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU02860 ABC_tran MHFCBNDO_00250 543734.LCABL_02410 6.97e-172 481.0 COG1108@1|root,COG1108@2|Bacteria,1V0SX@1239|Firmicutes,4HE09@91061|Bacilli,3F4BC@33958|Lactobacillaceae 91061|Bacilli U ABC 3 transport family znuB - - ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 MHFCBNDO_00251 543734.LCABL_02420 6.01e-211 582.0 COG0639@1|root,COG0639@2|Bacteria,1UZK9@1239|Firmicutes,4HG1F@91061|Bacilli,3F5JR@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase superfamily domain prpA3 - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - Metallophos_2 MHFCBNDO_00252 543734.LCABL_02430 1.52e-205 569.0 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,3F3XC@33958|Lactobacillaceae 91061|Bacilli I Dehydrogenase glxR - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 MHFCBNDO_00253 543734.LCABL_02440 0.0 1196.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,3F4E5@33958|Lactobacillaceae 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N MHFCBNDO_00254 543734.LCABL_02460 3.42e-240 662.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr MHFCBNDO_00255 543734.LCABL_02470 0.0 867.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans MHFCBNDO_00256 543734.LCABL_02480 4.9e-103 304.0 COG3103@1|root,COG3103@2|Bacteria,1VB6H@1239|Firmicutes,4I1GZ@91061|Bacilli,3F7SK@33958|Lactobacillaceae 91061|Bacilli T Sh3 type 3 domain protein - - - - - - - - - - - - LysM,SLAP MHFCBNDO_00257 543734.LCABL_02490 1.55e-173 484.0 COG1349@1|root,COG1349@2|Bacteria,1V1VH@1239|Firmicutes,4HHQ0@91061|Bacilli,3FC5T@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain glcR - - ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR MHFCBNDO_00258 543734.LCABL_02500 2.32e-188 523.0 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,4HVF8@91061|Bacilli,3FBRX@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 MHFCBNDO_00259 543734.LCABL_02510 8.9e-174 485.0 COG5523@1|root,COG5523@2|Bacteria,1U7F2@1239|Firmicutes,4IHB0@91061|Bacilli,3F9IA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF975) - - - - - - - - - - - - DUF975 MHFCBNDO_00260 1423732.BALS01000075_gene2102 4.42e-54 171.0 29PTZ@1|root,30AS5@2|Bacteria,1U71D@1239|Firmicutes,4IGVU@91061|Bacilli,3F8UT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00262 543734.LCABL_02540 1.26e-139 394.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HIQ4@91061|Bacilli,3F4SM@33958|Lactobacillaceae 91061|Bacilli U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 MHFCBNDO_00263 543734.LCABL_02550 2.04e-224 618.0 COG1397@1|root,COG1397@2|Bacteria,1TQXG@1239|Firmicutes,4HE5F@91061|Bacilli,3F509@33958|Lactobacillaceae 91061|Bacilli O ADP-ribosylglycohydrolase draG - - - - - - - - - - - ADP_ribosyl_GH MHFCBNDO_00264 543734.LCABL_02560 0.0 1010.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,3FC7X@33958|Lactobacillaceae 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn MHFCBNDO_00265 543734.LCABL_02570 1.44e-175 489.0 COG0500@1|root,COG0500@2|Bacteria,1VDQJ@1239|Firmicutes,4IT3M@91061|Bacilli,3F8EP@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase domain ypaC - - - - - - - - - - - Methyltransf_25 MHFCBNDO_00266 568703.LGG_00307 5.19e-90 263.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - MHFCBNDO_00268 543734.LCABL_02620 3.02e-71 214.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F7I4@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin MHFCBNDO_00269 543734.LCABL_02630 2.2e-176 492.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,3F4XE@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE MHFCBNDO_00270 543734.LCABL_02640 2.51e-98 286.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,3F63I@33958|Lactobacillaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 MHFCBNDO_00271 543734.LCABL_02650 2.29e-273 749.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,3F591@33958|Lactobacillaceae 91061|Bacilli E Receptor family ligand binding region livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 MHFCBNDO_00272 543734.LCABL_02660 1.04e-191 534.0 COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,3F56V@33958|Lactobacillaceae 91061|Bacilli U Branched-chain amino acid transport system / permease component livH - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 MHFCBNDO_00273 543734.LCABL_02670 1.1e-182 513.0 COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,3F44M@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid transport system / permease component livM - - ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 MHFCBNDO_00274 543734.LCABL_02680 3.01e-180 502.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,3F4IH@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid ATP-binding cassette transporter livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C MHFCBNDO_00275 543734.LCABL_02690 3.34e-159 447.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,3F3RP@33958|Lactobacillaceae 91061|Bacilli E ABC transporter livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran MHFCBNDO_00276 543734.LCABL_02700 7.59e-214 590.0 COG4814@1|root,COG4814@2|Bacteria,1V8NG@1239|Firmicutes,4HJ22@91061|Bacilli,3F41V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 MHFCBNDO_00277 543734.LCABL_02710 1.12e-303 829.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HE28@91061|Bacilli,3FC6Y@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts14C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC MHFCBNDO_00278 543734.LCABL_02720 4.1e-152 428.0 COG3010@1|root,COG3010@2|Bacteria,1VTI6@1239|Firmicutes,4HV5Q@91061|Bacilli,3F3YB@33958|Lactobacillaceae 91061|Bacilli G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) - - - - - - - - - - - - - MHFCBNDO_00279 543734.LCABL_02740 1.44e-149 421.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,3F4M3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC,NUDIX MHFCBNDO_00280 543734.LCABL_02750 3.24e-293 799.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,3F3Y4@33958|Lactobacillaceae 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme MHFCBNDO_00281 543734.LCABL_02760 3.14e-166 465.0 COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli,3F4K1@33958|Lactobacillaceae 91061|Bacilli F Purine nucleoside phosphorylase deoD - 2.4.2.1 ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 MHFCBNDO_00282 543734.LCABL_02770 3.91e-211 600.0 COG0791@1|root,COG0791@2|Bacteria,1VG0Z@1239|Firmicutes,4HBE9@91061|Bacilli,3F50V@33958|Lactobacillaceae 91061|Bacilli M NlpC P60 family protein p75 - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60,SLAP MHFCBNDO_00285 543734.LCABL_02800 0.0 895.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase nox - 1.6.3.4 ko:K17869 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim MHFCBNDO_00286 543734.LCABL_02810 2.06e-177 497.0 28MN3@1|root,2ZAXQ@2|Bacteria,1US2T@1239|Firmicutes,4HW4H@91061|Bacilli,3F55K@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00287 543734.LCABL_02820 1.14e-153 432.0 2EEPZ@1|root,338HP@2|Bacteria,1VJZJ@1239|Firmicutes,4HR6K@91061|Bacilli,3F55G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00288 543734.LCABL_02830 0.0 1569.0 COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,3F473@33958|Lactobacillaceae 91061|Bacilli KL DEAD_2 uvrB3 - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1 MHFCBNDO_00289 543734.LCABL_02840 1.42e-306 836.0 COG1653@1|root,COG1653@2|Bacteria,1TSBD@1239|Firmicutes,4IQ65@91061|Bacilli,3F5HX@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 MHFCBNDO_00290 543734.LCABL_02850 2.22e-110 323.0 29V33@1|root,30GGE@2|Bacteria,1UFZH@1239|Firmicutes,4IF1H@91061|Bacilli,3F5BQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00291 543734.LCABL_02860 0.0 1095.0 COG3525@1|root,COG3525@2|Bacteria,1TT9S@1239|Firmicutes,4HEM6@91061|Bacilli 91061|Bacilli G Gram-positive signal peptide protein, YSIRK family strH - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - G5,Glyco_hydro_20,Gram_pos_anchor,YSIRK_signal MHFCBNDO_00292 543734.LCABL_02870 9.12e-249 681.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,3F40I@33958|Lactobacillaceae 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI MHFCBNDO_00293 543734.LCABL_02880 5.43e-167 467.0 COG2188@1|root,COG2188@2|Bacteria,1UYYY@1239|Firmicutes,4HGI6@91061|Bacilli,3F5F4@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA MHFCBNDO_00294 543734.LCABL_02890 9.45e-280 765.0 COG2222@1|root,COG2222@2|Bacteria,1TQUT@1239|Firmicutes,4HDKQ@91061|Bacilli,3F3YS@33958|Lactobacillaceae 91061|Bacilli G SIS domain agaS - - ko:K02082 - - - - ko00000,ko01000 - - - SIS MHFCBNDO_00295 543734.LCABL_02900 6.46e-288 785.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,3F40F@33958|Lactobacillaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 MHFCBNDO_00296 543734.LCABL_02910 0.0 1242.0 COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,4HBAR@91061|Bacilli,3F5XU@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 35 bgaC - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - BetaGal_dom4_5,Glyco_hydro_35 MHFCBNDO_00297 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00298 543734.LCABL_02920 2.29e-107 310.0 COG3444@1|root,COG3444@2|Bacteria,1V46G@1239|Firmicutes,4HHPN@91061|Bacilli,3FC7S@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb MHFCBNDO_00299 543734.LCABL_02930 4.68e-206 571.0 COG3715@1|root,COG3715@2|Bacteria,1TSX0@1239|Firmicutes,4HBRB@91061|Bacilli,3F4X4@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor MHFCBNDO_00300 543734.LCABL_02940 3.66e-187 521.0 COG3716@1|root,COG3716@2|Bacteria,1UMKU@1239|Firmicutes,4HC75@91061|Bacilli,3F434@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA MHFCBNDO_00301 543734.LCABL_02950 2.72e-85 251.0 COG2893@1|root,COG2893@2|Bacteria,1VB8U@1239|Firmicutes,4HKV5@91061|Bacilli,3F7YU@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man MHFCBNDO_00302 543734.LCABL_02960 9.25e-288 787.0 2E865@1|root,332JJ@2|Bacteria,1VJ1K@1239|Firmicutes,4IFBU@91061|Bacilli,3F662@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2325) - - - - - - - - - - - - DUF2325 MHFCBNDO_00303 1423816.BACQ01000062_gene2361 1.3e-243 674.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 MHFCBNDO_00304 543734.LCABL_03000 1.81e-250 688.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HV4S@91061|Bacilli,3F9GC@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 MHFCBNDO_00305 543734.LCABL_03010 0.0 867.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HEGS@91061|Bacilli,3F744@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane - - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC MHFCBNDO_00306 543734.LCABL_03020 2.96e-78 232.0 COG1440@1|root,COG1440@2|Bacteria,1V6UA@1239|Firmicutes,4HK0J@91061|Bacilli,3F8G8@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB MHFCBNDO_00307 543734.LCABL_03030 2.9e-68 207.0 COG1447@1|root,COG1447@2|Bacteria,1VCDD@1239|Firmicutes,4HZCJ@91061|Bacilli,3F7P9@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit - - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA MHFCBNDO_00308 543734.LCABL_03040 4.06e-240 660.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,3F55I@33958|Lactobacillaceae 91061|Bacilli E M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 MHFCBNDO_00309 543734.LCABL_03050 0.0 1159.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TS2U@1239|Firmicutes,4HTK5@91061|Bacilli,3F6RZ@33958|Lactobacillaceae 91061|Bacilli GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,PRD,PTS_EIIA_2 MHFCBNDO_00310 543734.LCABL_03060 4.75e-307 836.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,3F45V@33958|Lactobacillaceae 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 MHFCBNDO_00311 543734.LCABL_03070 0.0 1049.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 MHFCBNDO_00312 543734.LCABL_03080 9.77e-144 406.0 COG3153@1|root,COG3153@2|Bacteria,1V3PW@1239|Firmicutes,4HGZK@91061|Bacilli,3F7G3@33958|Lactobacillaceae 91061|Bacilli S Acetyltransferase (GNAT) family - - - ko:K03824 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_9 MHFCBNDO_00315 543734.LCABL_03100 1.08e-121 348.0 COG4721@1|root,COG4721@2|Bacteria,1V2G5@1239|Firmicutes,4IRFG@91061|Bacilli,3FBNZ@33958|Lactobacillaceae 91061|Bacilli S ABC-type cobalt transport system, permease component - - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt MHFCBNDO_00316 543734.LCABL_03110 1.56e-310 847.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,3FBS0@33958|Lactobacillaceae 91061|Bacilli P ABC transporter - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran MHFCBNDO_00317 543734.LCABL_03120 6.59e-143 404.0 COG0619@1|root,COG0619@2|Bacteria,1TUDZ@1239|Firmicutes,4HCPC@91061|Bacilli,3F4FG@33958|Lactobacillaceae 91061|Bacilli P cobalt transport ykoC - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ MHFCBNDO_00318 543734.LCABL_03130 3.99e-165 461.0 COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,4HCPF@91061|Bacilli,3FB7U@33958|Lactobacillaceae 91061|Bacilli K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway tenA - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 MHFCBNDO_00319 543734.LCABL_03140 2.08e-106 308.0 COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,4HHG6@91061|Bacilli,3F6M6@33958|Lactobacillaceae 91061|Bacilli S Thiamine-precursor transporter protein (ThiW) thiW - - - - - - - - - - - ThiW MHFCBNDO_00320 543734.LCABL_03150 1.01e-192 535.0 COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,4HFTJ@91061|Bacilli,3F43J@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM - 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK MHFCBNDO_00321 543734.LCABL_03160 4.27e-138 392.0 COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,3FB7Y@33958|Lactobacillaceae 91061|Bacilli H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI MHFCBNDO_00322 543734.LCABL_03170 1.56e-189 527.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,3F3NA@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin MHFCBNDO_00323 543734.LCABL_03180 0.0 942.0 COG0531@1|root,COG0531@2|Bacteria,1UYSD@1239|Firmicutes,4IPMN@91061|Bacilli,3F48U@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 MHFCBNDO_00324 543734.LCABL_03200 1.16e-45 147.0 2AIT2@1|root,3199Z@2|Bacteria,1U879@1239|Firmicutes,4II4Z@91061|Bacilli,3FAMW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00325 543734.LCABL_03210 2.08e-240 660.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4HE07@91061|Bacilli,3F44Q@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding proteins and sugar binding domain of LacI family rbsR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 MHFCBNDO_00326 543734.LCABL_03220 3.66e-85 251.0 COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,4HIFW@91061|Bacilli,3F6GA@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose rbsD - 5.4.99.62 ko:K06726 ko02010,map02010 - R08247 RC02247 ko00000,ko00001,ko01000 - - - RbsD_FucU MHFCBNDO_00327 543734.LCABL_03230 0.0 971.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,3FBUB@33958|Lactobacillaceae 91061|Bacilli G ABC transporter rbsA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran MHFCBNDO_00328 543734.LCABL_03240 8.01e-197 550.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,3F5NF@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family rbsC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 MHFCBNDO_00329 543734.LCABL_03250 5.72e-214 592.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,4HCSN@91061|Bacilli,3FCEY@33958|Lactobacillaceae 91061|Bacilli G Periplasmic binding protein domain rbsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 MHFCBNDO_00330 543734.LCABL_03260 1.34e-207 575.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HE6Z@91061|Bacilli,3FB6B@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB MHFCBNDO_00331 543734.LCABL_03280 0.0 1295.0 COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,4IQSR@91061|Bacilli,3F5K3@33958|Lactobacillaceae 91061|Bacilli M NTF2-like N-terminal transpeptidase domain pbpC - - ko:K21467 - - - - ko00000,ko01011 - - - MecA_N,PBP_dimer,Transpeptidase MHFCBNDO_00332 543734.LCABL_03290 9.23e-305 834.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F4D4@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1,MFS_3 MHFCBNDO_00333 543734.LCABL_03300 2.2e-95 278.0 COG1846@1|root,COG1846@2|Bacteria,1V939@1239|Firmicutes,4HJRC@91061|Bacilli,3F7MR@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR MHFCBNDO_00334 543734.LCABL_03310 1.75e-129 367.0 2DEN3@1|root,32U3P@2|Bacteria,1VXXQ@1239|Firmicutes,4HXNG@91061|Bacilli,3F73U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00335 543734.LCABL_03320 4.22e-41 135.0 2ATAB@1|root,31ITC@2|Bacteria,1U735@1239|Firmicutes,4IGXP@91061|Bacilli,3F8WX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00336 543734.LCABL_03330 1.12e-82 249.0 29QQ0@1|root,30BPR@2|Bacteria,1U8FC@1239|Firmicutes,4IID8@91061|Bacilli,3FAX8@33958|Lactobacillaceae 543734.LCABL_03330|- - - - - - - - - - - - - - - - MHFCBNDO_00337 543734.LCABL_03340 1.06e-82 250.0 29QQ0@1|root,30BPR@2|Bacteria,1U8FC@1239|Firmicutes,4IID8@91061|Bacilli,3FAX8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00338 543734.LCABL_03350 7.42e-89 260.0 28ZBI@1|root,2ZM3D@2|Bacteria,1W5K5@1239|Firmicutes,4I1Q6@91061|Bacilli,3F825@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 MHFCBNDO_00339 543734.LCABL_03360 2.1e-121 347.0 29P6Z@1|root,30A52@2|Bacteria,1U67I@1239|Firmicutes,4IFY3@91061|Bacilli,3F796@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00340 1423732.BALS01000032_gene234 8.83e-114 330.0 COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,4I2PJ@91061|Bacilli,3F4H6@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_00341 543734.LCABL_03400 3.93e-162 455.0 29P41@1|root,30A28@2|Bacteria,1U63C@1239|Firmicutes,4IFSS@91061|Bacilli,3F6Y1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00342 543734.LCABL_03410 8.53e-139 394.0 29QRY@1|root,30BRT@2|Bacteria,1U8J4@1239|Firmicutes,4IIH3@91061|Bacilli,3FB1I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00343 543734.LCABL_03420 3.9e-172 482.0 2AIFZ@1|root,33KBF@2|Bacteria,1UPZ6@1239|Firmicutes,4IVDJ@91061|Bacilli,3F6BW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00344 543734.LCABL_03440 0.0 951.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4ISAE@91061|Bacilli,3FBRV@33958|Lactobacillaceae 91061|Bacilli C HI0933-like protein frdC - 1.3.5.1,1.3.5.4 ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C MHFCBNDO_00345 543734.LCABL_03450 4.69e-250 702.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4H9N4@91061|Bacilli,3F64K@33958|Lactobacillaceae 91061|Bacilli GKT transcriptional antiterminator - - - - - - - - - - - - HTH_11,Mga,PRD,PTS_EIIA_2 MHFCBNDO_00346 543734.LCABL_03470 3.38e-66 201.0 COG3414@1|root,COG3414@2|Bacteria,1VBHM@1239|Firmicutes,4HM7H@91061|Bacilli,3F96C@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB MHFCBNDO_00347 543734.LCABL_03480 6.55e-291 796.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HBAD@91061|Bacilli,3F4Y4@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component - - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT MHFCBNDO_00348 543734.LCABL_03490 5.04e-90 264.0 2DQQD@1|root,32UPI@2|Bacteria,1VIC6@1239|Firmicutes,4HSMN@91061|Bacilli,3F8E7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - TPR_1 MHFCBNDO_00349 543734.LCABL_03500 6.47e-208 574.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HA99@91061|Bacilli,3F611@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase MHFCBNDO_00350 543734.LCABL_03510 7.78e-150 421.0 COG0645@1|root,COG0645@2|Bacteria,1V4KB@1239|Firmicutes,4HI0A@91061|Bacilli,3F7CA@33958|Lactobacillaceae 91061|Bacilli S Zeta toxin - - - - - - - - - - - - AAA_33,Zeta_toxin MHFCBNDO_00351 543734.LCABL_03520 3.2e-203 561.0 COG1378@1|root,COG1378@2|Bacteria,1TTRR@1239|Firmicutes,4IHFC@91061|Bacilli,3F9RY@33958|Lactobacillaceae 91061|Bacilli K Sugar-specific transcriptional regulator TrmB - - - - - - - - - - - - TrmB MHFCBNDO_00352 543734.LCABL_03530 9.64e-191 531.0 COG0730@1|root,COG0730@2|Bacteria,1TQ8H@1239|Firmicutes,4IIWZ@91061|Bacilli,3F7J9@33958|Lactobacillaceae 91061|Bacilli S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE MHFCBNDO_00353 543734.LCABL_03540 1.96e-227 627.0 COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,4HBWI@91061|Bacilli,3F5HH@33958|Lactobacillaceae 91061|Bacilli E Ornithine cyclodeaminase/mu-crystallin family - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall MHFCBNDO_00354 543734.LCABL_03550 1.91e-191 530.0 COG0596@1|root,COG0596@2|Bacteria,1UKJS@1239|Firmicutes,4ITJ3@91061|Bacilli 91061|Bacilli S Alpha/beta hydrolase family - - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 MHFCBNDO_00357 543734.LCABL_03610 2.37e-91 267.0 COG3576@1|root,COG3576@2|Bacteria,1VW4G@1239|Firmicutes,4HW37@91061|Bacilli,3F6IW@33958|Lactobacillaceae 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx MHFCBNDO_00358 1291743.LOSG293_590030 5.11e-93 270.0 2AK1X@1|root,31ARI@2|Bacteria,1V717@1239|Firmicutes,4HIQ9@91061|Bacilli,3F6WW@33958|Lactobacillaceae 91061|Bacilli S Pyrimidine dimer DNA glycosylase yqeB - - - - - - - - - - - Pyr_excise MHFCBNDO_00359 543734.LCABL_03660 2.79e-193 538.0 COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4HFV8@91061|Bacilli 91061|Bacilli V Beta-lactamase bla1 - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2,zinc_ribbon_2 MHFCBNDO_00360 543734.LCABL_03670 3.67e-109 317.0 2EM6V@1|root,33EW2@2|Bacteria,1VNUQ@1239|Firmicutes,4HRSG@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00361 543734.LCABL_03690 1.23e-228 630.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,3F3PB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator msmR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 MHFCBNDO_00362 543734.LCABL_03700 1.22e-181 507.0 COG3715@1|root,COG3715@2|Bacteria,1UYP8@1239|Firmicutes,4HFQS@91061|Bacilli,3FC9E@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor MHFCBNDO_00363 543734.LCABL_03710 3.5e-166 467.0 COG3716@1|root,COG3716@2|Bacteria,1UMKU@1239|Firmicutes,4HCQB@91061|Bacilli,3FBHN@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA MHFCBNDO_00364 1154860.SAG0136_07715 1.56e-282 780.0 COG3119@1|root,COG3119@2|Bacteria,1TSHE@1239|Firmicutes,4IQVE@91061|Bacilli 91061|Bacilli P Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - DUF4976,Sulfatase MHFCBNDO_00365 543734.LCABL_03770 1.01e-213 589.0 COG1262@1|root,COG1262@2|Bacteria,1TT4R@1239|Firmicutes,4HA8D@91061|Bacilli 91061|Bacilli S Sulfatase-modifying factor enzyme 1 pkn1 - - - - - - - - - - - DinB_2,FGE-sulfatase MHFCBNDO_00366 543734.LCABL_03780 1.72e-169 475.0 COG0730@1|root,COG0730@2|Bacteria,1UY5F@1239|Firmicutes,4HEQF@91061|Bacilli,3F7B6@33958|Lactobacillaceae 91061|Bacilli S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE MHFCBNDO_00367 543734.LCABL_03790 3.72e-235 649.0 COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,4HEMS@91061|Bacilli,3F89R@33958|Lactobacillaceae 91061|Bacilli C Iron-sulfur cluster-binding domain ydeM3 - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM,SPASM MHFCBNDO_00368 543734.LCABL_03840 1.72e-202 559.0 COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,4HD64@91061|Bacilli,3FCD2@33958|Lactobacillaceae 91061|Bacilli S Putative esterase estA - - ko:K03930 - - - - ko00000,ko01000 - CE1 - Esterase MHFCBNDO_00369 543734.LCABL_03850 1.23e-193 538.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component - - - ko:K02796,ko:K17467 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 M00276,M00610 R02630,R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.17 - - EIID-AGA MHFCBNDO_00370 543734.LCABL_03860 2.28e-172 482.0 COG3715@1|root,COG3715@2|Bacteria,1TSX0@1239|Firmicutes,4HBRB@91061|Bacilli,3FBHQ@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor MHFCBNDO_00371 543734.LCABL_03870 1.12e-116 334.0 COG3444@1|root,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli,3F4PU@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb MHFCBNDO_00372 543734.LCABL_03880 8.5e-91 266.0 COG2893@1|root,COG2893@2|Bacteria,1VCJ2@1239|Firmicutes,4HPXK@91061|Bacilli,3F7TA@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man MHFCBNDO_00373 543734.LCABL_03890 2.3e-56 194.0 COG1221@1|root,COG3933@1|root,COG1221@2|Bacteria,COG3933@2|Bacteria,1VSHE@1239|Firmicutes,4HB6T@91061|Bacilli,3F3N6@33958|Lactobacillaceae 91061|Bacilli K Sigma-54 interaction domain - - - ko:K19505 - - - - ko00000,ko03000 - - - EIIA-man,PRD,Sigma54_activat MHFCBNDO_00374 543734.LCABL_03890 0.0 1552.0 COG1221@1|root,COG3933@1|root,COG1221@2|Bacteria,COG3933@2|Bacteria,1VSHE@1239|Firmicutes,4HB6T@91061|Bacilli,3F3N6@33958|Lactobacillaceae 91061|Bacilli K Sigma-54 interaction domain - - - ko:K19505 - - - - ko00000,ko03000 - - - EIIA-man,PRD,Sigma54_activat MHFCBNDO_00375 543734.LCABL_03900 3.69e-301 823.0 COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,3F4R8@33958|Lactobacillaceae 91061|Bacilli K Sigma-54 factor, core binding domain rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD MHFCBNDO_00376 543734.LCABL_03910 0.0 920.0 COG3711@1|root,COG3711@2|Bacteria,1TSGM@1239|Firmicutes,4HB3W@91061|Bacilli,3F482@33958|Lactobacillaceae 91061|Bacilli K PRD domain - - - ko:K02538 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB MHFCBNDO_00377 543734.LCABL_03920 1.05e-101 295.0 COG1762@1|root,COG1762@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system ptsN GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 - - PTS_EIIA_2 MHFCBNDO_00378 543734.LCABL_03930 7.37e-223 614.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HD42@91061|Bacilli,3F58Z@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase MHFCBNDO_00379 543734.LCABL_03940 5.02e-105 303.0 COG1762@1|root,COG1762@2|Bacteria,1V5TG@1239|Firmicutes,4HND7@91061|Bacilli,3F7H8@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.202 ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 MHFCBNDO_00380 543734.LCABL_03950 1.08e-63 195.0 COG1445@1|root,COG1445@2|Bacteria,1VASC@1239|Firmicutes,4HKYF@91061|Bacilli,3F7K8@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.202 ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_IIB MHFCBNDO_00381 543734.LCABL_03960 1.42e-219 610.0 COG1299@1|root,COG1299@2|Bacteria,1TPKU@1239|Firmicutes,4H9XS@91061|Bacilli,3F52Q@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase System - - - ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.2.1 - - PTS_EIIC MHFCBNDO_00382 543734.LCABL_03970 2.14e-232 639.0 COG2017@1|root,COG2017@2|Bacteria,1V5SP@1239|Firmicutes,4IRIW@91061|Bacilli,3F96V@33958|Lactobacillaceae 91061|Bacilli G Domain of unknown function (DUF4432) - - - - - - - - - - - - DUF4432 MHFCBNDO_00383 543734.LCABL_03980 1.35e-171 478.0 COG3822@1|root,COG3822@2|Bacteria,1UXBF@1239|Firmicutes,4HVN6@91061|Bacilli,3F9JP@33958|Lactobacillaceae 91061|Bacilli S Pfam:DUF1498 - - 5.3.1.15 ko:K09988 ko00040,map00040 - R01898 RC00516 ko00000,ko00001,ko01000 - - - Lyx_isomer MHFCBNDO_00384 543734.LCABL_03990 0.0 959.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,3F4R2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the FGGY kinase family xylB - 2.7.1.17,2.7.1.53 ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 M00014 R01639,R01901,R07127 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N MHFCBNDO_00385 543734.LCABL_04010 2.86e-97 283.0 COG1762@1|root,COG1762@2|Bacteria,1VDC4@1239|Firmicutes,4HNDE@91061|Bacilli,3FCBG@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - ko:K11201 - M00306 - - ko00000,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 MHFCBNDO_00386 543734.LCABL_04020 0.0 981.0 COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1TPKU@1239|Firmicutes,4HD9N@91061|Bacilli,3FCBF@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit pts31BC - - ko:K11202,ko:K11203 - M00306 - - ko00000,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIC,PTS_IIB MHFCBNDO_00387 543734.LCABL_04030 7.73e-291 793.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F5DH@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class I and II malY - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 MHFCBNDO_00388 543734.LCABL_04040 0.0 1096.0 2DX0A@1|root,342SP@2|Bacteria,1UIXQ@1239|Firmicutes,4ISW1@91061|Bacilli,3F9EI@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - - - - - - - - - - HTH_11,PTS_EIIA_2 MHFCBNDO_00389 543734.LCABL_04050 0.0 1194.0 COG3711@1|root,COG3711@2|Bacteria,1TQTV@1239|Firmicutes,4HFDM@91061|Bacilli 91061|Bacilli K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - - - - - - - - - - HTH_11,PRD,PTS_EIIA_2 MHFCBNDO_00390 543734.LCABL_04060 4.92e-203 562.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HD42@91061|Bacilli,3F58Z@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase MHFCBNDO_00391 543734.LCABL_04070 0.0 1236.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F9FH@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system - - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB MHFCBNDO_00392 543734.LCABL_04110 1.5e-187 521.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli,3F9T3@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short MHFCBNDO_00393 543734.LCABL_04120 5.33e-98 285.0 COG2893@1|root,COG2893@2|Bacteria,1VCQI@1239|Firmicutes,4I36M@91061|Bacilli,3F6W9@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191,2.7.1.203 ko:K02793,ko:K17464 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 M00276,M00610 R02630,R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.6.1.17 - - EIIA-man MHFCBNDO_00394 543734.LCABL_04130 5.98e-111 319.0 COG3444@1|root,COG3444@2|Bacteria,1V92Y@1239|Firmicutes,4HXTT@91061|Bacilli 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.203 ko:K17465 ko00030,ko01120,ko02060,map00030,map01120,map02060 M00610 R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.17 - - PTSIIB_sorb MHFCBNDO_00395 543734.LCABL_04140 5.6e-170 475.0 COG3715@1|root,COG3715@2|Bacteria,1V07Y@1239|Firmicutes,4IQM7@91061|Bacilli 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K17466 ko00030,ko01120,ko02060,map00030,map01120,map02060 M00610 R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1.17 - - EII-Sor MHFCBNDO_00396 543734.LCABL_04150 5.44e-198 550.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component - - - ko:K02796,ko:K17467 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 M00276,M00610 R02630,R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.17 - - EIID-AGA MHFCBNDO_00397 543734.LCABL_04160 1.83e-279 764.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,3F448@33958|Lactobacillaceae 91061|Bacilli C mannitol-1-phosphate 5-dehydrogenase activity mtlD - 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C MHFCBNDO_00398 543734.LCABL_04170 1.05e-146 414.0 COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,4HGZY@91061|Bacilli,3FA2V@33958|Lactobacillaceae 91061|Bacilli S Dak2 dhaL - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Dak2 MHFCBNDO_00399 543734.LCABL_04180 1.45e-236 651.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,4HU2R@91061|Bacilli,3F9K8@33958|Lactobacillaceae 91061|Bacilli G Dak1 domain - - 2.7.1.121 ko:K05878 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak1 MHFCBNDO_00400 543734.LCABL_04190 5.39e-152 427.0 COG0269@1|root,COG0269@2|Bacteria,1TQ55@1239|Firmicutes,4HBMT@91061|Bacilli,3F54B@33958|Lactobacillaceae 91061|Bacilli G Orotidine 5'-phosphate decarboxylase / HUMPS family hxlA GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.2.43 ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338 RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase MHFCBNDO_00401 543734.LCABL_04200 5.82e-130 369.0 COG0794@1|root,COG0794@2|Bacteria,1V3UJ@1239|Firmicutes,4HH5G@91061|Bacilli,3F7I2@33958|Lactobacillaceae 91061|Bacilli M sugar phosphate isomerase involved in capsule formation hxlB - 5.3.1.27 ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05339,R09780 RC00377 ko00000,ko00001,ko00002,ko01000 - - - SIS MHFCBNDO_00402 543734.LCABL_04210 5.41e-171 478.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4I39G@91061|Bacilli,3FA85@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA MHFCBNDO_00403 543734.LCABL_04220 4.08e-311 846.0 COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,4HBV4@91061|Bacilli,3F602@33958|Lactobacillaceae 91061|Bacilli E Alcohol dehydrogenase GroES-like domain - - - ko:K19956 ko00051,map00051 - R03234 RC00089 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N MHFCBNDO_00404 543734.LCABL_04230 2.56e-221 611.0 COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4HCAR@91061|Bacilli,3F4PP@33958|Lactobacillaceae 91061|Bacilli K sugar-binding domain protein - - - - - - - - - - - - Sugar-bind MHFCBNDO_00405 543734.LCABL_04240 5.02e-186 517.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli,3F4CR@33958|Lactobacillaceae 91061|Bacilli IQ NAD dependent epimerase/dehydratase family srlD2 - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short MHFCBNDO_00406 543734.LCABL_04250 2.06e-88 260.0 COG2893@1|root,COG2893@2|Bacteria,1VGQT@1239|Firmicutes,4HNXM@91061|Bacilli,3F7YA@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.206 ko:K02812 ko00051,ko02060,map00051,map02060 M00278 R04076 RC01069,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.3 - - EIIA-man MHFCBNDO_00407 543734.LCABL_04260 4.08e-112 322.0 COG3444@1|root,COG3444@2|Bacteria,1V3X7@1239|Firmicutes,4HH17@91061|Bacilli,3F6T0@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.206 ko:K02813 ko00051,ko02060,map00051,map02060 M00278 R04076 RC01069,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.3 - - PTSIIB_sorb MHFCBNDO_00408 543734.LCABL_04270 3.93e-184 513.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli,3F5QK@33958|Lactobacillaceae 91061|Bacilli U PTS system sorbose-specific iic component - - - ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277,M00278 R02630,R04076,R08366 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.3,4.A.6.1.4 - - EII-Sor MHFCBNDO_00409 543734.LCABL_04280 5.03e-194 539.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component manZ - - ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00278 R02630,R04076 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.3 - - EIID-AGA MHFCBNDO_00410 543734.LCABL_04290 3.89e-210 581.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HGMN@91061|Bacilli,3FCBA@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II kbaY - 4.1.2.13,4.1.2.40 ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01069,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase MHFCBNDO_00411 543734.LCABL_04300 0.0 909.0 COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,4H9UV@91061|Bacilli 91061|Bacilli P transporter sdcS GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0034220,GO:0044425,GO:0051179,GO:0051234,GO:0055085,GO:0098656 - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp MHFCBNDO_00412 543734.LCABL_04310 3.33e-303 827.0 COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,4HBWH@91061|Bacilli 91061|Bacilli C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_oxidored MHFCBNDO_00413 543734.LCABL_04320 1.39e-202 561.0 COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HFSV@91061|Bacilli,3F48I@33958|Lactobacillaceae 1239|Firmicutes K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate MHFCBNDO_00414 543734.LCABL_04330 2.16e-203 562.0 COG1912@1|root,COG1912@2|Bacteria,1TSR3@1239|Firmicutes,4HAW6@91061|Bacilli,3F3JD@33958|Lactobacillaceae 91061|Bacilli K S-adenosyl-l-methionine hydroxide adenosyltransferase XK27_10120 - - - - - - - - - - - SAM_adeno_trans MHFCBNDO_00415 543734.LCABL_04350 1.05e-127 363.0 COG4720@1|root,COG4720@2|Bacteria,1V1GT@1239|Firmicutes,4HGAE@91061|Bacilli,3F5A7@33958|Lactobacillaceae 91061|Bacilli S UPF0397 protein - - - ko:K16924 - M00582 - - ko00000,ko00002,ko02000 3.A.1.29 - - ECF-ribofla_trS MHFCBNDO_00416 543734.LCABL_04360 0.0 1093.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,3F4XP@33958|Lactobacillaceae 91061|Bacilli P ABC transporter, ATP-binding protein ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 MHFCBNDO_00417 543734.LCABL_04370 4.65e-191 531.0 COG0619@1|root,COG0619@2|Bacteria,1TPMV@1239|Firmicutes,4HBTW@91061|Bacilli,3F3Y9@33958|Lactobacillaceae 91061|Bacilli P cobalt transport cbiQ - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iSB619.SA_RS14165 CbiQ MHFCBNDO_00418 543734.LCABL_04400 0.0 1630.0 COG1221@1|root,COG3933@1|root,COG1221@2|Bacteria,COG3933@2|Bacteria,1VSHE@1239|Firmicutes,4HB6T@91061|Bacilli,3F3N6@33958|Lactobacillaceae 91061|Bacilli K Sigma-54 interaction domain - - - - - - - - - - - - EIIA-man,PRD,Sigma54_activ_2,Sigma54_activat MHFCBNDO_00419 543734.LCABL_04410 1.17e-95 279.0 COG2893@1|root,COG2893@2|Bacteria,1VBC1@1239|Firmicutes,4IQPC@91061|Bacilli,3F6SH@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - - ko:K02744 ko00052,ko02060,map00052,map02060 M00277,M00287 R08366,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.4,4.A.6.1.5 - - EIIA-man MHFCBNDO_00420 543734.LCABL_04420 2.66e-117 335.0 COG3444@1|root,COG3444@2|Bacteria,1UZRR@1239|Firmicutes,4HV38@91061|Bacilli,3FCCV@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb MHFCBNDO_00421 543734.LCABL_04430 6.62e-197 546.0 COG3715@1|root,COG3715@2|Bacteria,1U8TN@1239|Firmicutes,4HE9V@91061|Bacilli,3F4QF@33958|Lactobacillaceae 91061|Bacilli M PTS system sorbose-specific iic component levC - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor MHFCBNDO_00422 543734.LCABL_04440 2.15e-199 552.0 COG3716@1|root,COG3716@2|Bacteria,1UNST@1239|Firmicutes,4HEX7@91061|Bacilli,3F5DT@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component levD - - ko:K02771 ko00051,ko02060,map00051,map02060 M00304 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1.2 - - EIID-AGA MHFCBNDO_00423 913848.AELK01000047_gene2613 9.35e-74 221.0 2EC9R@1|root,33683@2|Bacteria,1VIEC@1239|Firmicutes,4HSN3@91061|Bacilli,3F7A0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00424 1423806.JCM15457_625 0.0 939.0 COG1621@1|root,COG3386@1|root,COG1621@2|Bacteria,COG3386@2|Bacteria,1UX3T@1239|Firmicutes,4I2IG@91061|Bacilli,3F8QB@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 32 - - 3.2.1.65 ko:K01212 ko00500,map00500 - R05624,R11311 RC03278 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32N MHFCBNDO_00426 543734.LCABL_04470 1.24e-154 434.0 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli,3F56K@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 MHFCBNDO_00427 543734.LCABL_04480 1.37e-172 482.0 COG1349@1|root,COG1349@2|Bacteria,1UXJ3@1239|Firmicutes,4I2XW@91061|Bacilli,3F89K@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR MHFCBNDO_00428 543734.LCABL_04490 2.05e-146 413.0 COG0269@1|root,COG0269@2|Bacteria,1TQ55@1239|Firmicutes,4HBMT@91061|Bacilli,3F54B@33958|Lactobacillaceae 91061|Bacilli G Orotidine 5'-phosphate decarboxylase / HUMPS family - - 4.1.2.43 ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338 RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase MHFCBNDO_00429 543734.LCABL_04500 2.35e-125 357.0 COG0794@1|root,COG0794@2|Bacteria,1UYG2@1239|Firmicutes,4HE2U@91061|Bacilli,3FB4E@33958|Lactobacillaceae 91061|Bacilli M SIS domain - - 5.3.1.27 ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05339,R09780 RC00377 ko00000,ko00001,ko00002,ko01000 - - - SIS MHFCBNDO_00430 1545702.LACWKB8_0174 1.64e-78 244.0 COG1349@1|root,COG1349@2|Bacteria,1UYMW@1239|Firmicutes,4HBQ1@91061|Bacilli,3FC5W@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR MHFCBNDO_00431 1545702.LACWKB8_0173 1.3e-145 415.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli,3F9T3@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short MHFCBNDO_00432 1158607.UAU_01359 6.38e-301 839.0 COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1TPE3@1239|Firmicutes,4HUCH@91061|Bacilli,4B1JC@81852|Enterococcaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.197 ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB MHFCBNDO_00433 1158607.UAU_01360 5.4e-191 540.0 COG0246@1|root,COG0246@2|Bacteria,1TS6C@1239|Firmicutes,4HTKF@91061|Bacilli,4B1E9@81852|Enterococcaceae 91061|Bacilli G Mannitol dehydrogenase C-terminal domain - - 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh_C MHFCBNDO_00435 1423815.BACR01000037_gene1783 2.71e-70 220.0 COG0778@1|root,COG0778@2|Bacteria,1V6AG@1239|Firmicutes,4HN5N@91061|Bacilli,3F6YM@33958|Lactobacillaceae 91061|Bacilli C nitroreductase - - - - - - - - - - - - Nitroreductase MHFCBNDO_00436 543734.LCABL_04580 9.19e-304 828.0 COG0477@1|root,COG0477@2|Bacteria,1TQIJ@1239|Firmicutes,4HAM0@91061|Bacilli,3F3N4@33958|Lactobacillaceae 91061|Bacilli EGP Sugar (and other) transporter proP - - ko:K03761,ko:K03762 - - - - ko00000,ko02000 2.A.1.6.2,2.A.1.6.4 - - MFS_1,Sugar_tr MHFCBNDO_00438 568703.LGG_00485 1.33e-17 74.7 29QPW@1|root,30BPK@2|Bacteria,1U8F6@1239|Firmicutes,4IID2@91061|Bacilli,3FAX1@33958|Lactobacillaceae 91061|Bacilli S YvrJ protein family - - - - - - - - - - - - YvrJ MHFCBNDO_00439 543734.LCABL_04610 2.34e-184 512.0 COG3757@1|root,COG3757@2|Bacteria,1V3SH@1239|Firmicutes,4HNR1@91061|Bacilli,3F6ZF@33958|Lactobacillaceae 91061|Bacilli M hydrolase, family 25 - - - - - - - - - - - - Glyco_hydro_25,LysM,SH3_5 MHFCBNDO_00440 543734.LCABL_04620 1.68e-170 476.0 COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,3F3VA@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family ypiA - - - - - - - - - - - adh_short MHFCBNDO_00441 543734.LCABL_04630 1.25e-148 418.0 COG0716@1|root,COG0716@2|Bacteria,1V465@1239|Firmicutes,4HN5X@91061|Bacilli 91061|Bacilli C Flavodoxin - - - - - - - - - - - - Flavodoxin_4 MHFCBNDO_00442 543734.LCABL_04640 5.12e-112 322.0 COG1309@1|root,COG1309@2|Bacteria,1V4D3@1239|Firmicutes,4HJ8Z@91061|Bacilli,3F6ZM@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N MHFCBNDO_00443 543734.LCABL_04650 5.69e-238 656.0 COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,3F3K5@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease yxeA - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD MHFCBNDO_00444 543734.LCABL_04660 8.27e-153 430.0 COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli,3F4RP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_00445 543734.LCABL_04690 0.0 909.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase npr - 1.11.1.1 ko:K05910 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim MHFCBNDO_00446 543734.LCABL_04700 7.51e-194 538.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,3F55S@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - - - - - - - - - - - Hydrolase_3 MHFCBNDO_00447 543734.LCABL_04710 1.49e-58 181.0 COG3041@1|root,COG3041@2|Bacteria,1U69Z@1239|Firmicutes,4IG17@91061|Bacilli,3F7EP@33958|Lactobacillaceae 91061|Bacilli S Bacterial toxin of type II toxin-antitoxin system, YafQ - - - ko:K19157 - - - - ko00000,ko01000,ko02048 - - - YafQ_toxin MHFCBNDO_00448 543734.LCABL_04720 2.33e-237 653.0 COG1609@1|root,COG1609@2|Bacteria,1TRHK@1239|Firmicutes,4HB9P@91061|Bacilli,3F5FI@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding proteins and sugar binding domain of LacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 MHFCBNDO_00449 543734.LCABL_04730 6.03e-109 314.0 COG3444@1|root,COG3444@2|Bacteria,1V8BP@1239|Firmicutes,4HWNX@91061|Bacilli,3F6R3@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb MHFCBNDO_00450 543734.LCABL_04740 2.18e-177 496.0 COG3715@1|root,COG3715@2|Bacteria,1TSX0@1239|Firmicutes,4HBRB@91061|Bacilli,3F4X4@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor MHFCBNDO_00451 543734.LCABL_04750 7.9e-196 544.0 COG3716@1|root,COG3716@2|Bacteria,1TSXA@1239|Firmicutes,4IQM2@91061|Bacilli,3FBHP@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA MHFCBNDO_00452 543734.LCABL_04760 0.0 1533.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HB1D@91061|Bacilli,3F4CE@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 31 family - - - - - - - - - - - - Glyco_hydro_31 MHFCBNDO_00453 543734.LCABL_04770 5.07e-89 261.0 COG2893@1|root,COG2893@2|Bacteria,1V7TP@1239|Firmicutes,4IQPD@91061|Bacilli,3F76S@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man MHFCBNDO_00454 543734.LCABL_04780 0.0 1182.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C MHFCBNDO_00455 1423816.BACQ01000064_gene2451 0.0 1072.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran MHFCBNDO_00457 543734.LCABL_04840 0.0 1401.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,3F3Y3@33958|Lactobacillaceae 91061|Bacilli V domain protein pip - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 MHFCBNDO_00458 543734.LCABL_04860 3.7e-199 552.0 COG1464@1|root,COG1464@2|Bacteria,1V0Z6@1239|Firmicutes,4HBBW@91061|Bacilli,3FC6K@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family metQ1 - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 MHFCBNDO_00459 543734.LCABL_04870 5.6e-251 687.0 COG3049@1|root,COG3049@2|Bacteria,1UZCV@1239|Firmicutes,4HFHU@91061|Bacilli,3FB8Y@33958|Lactobacillaceae 91061|Bacilli M Linear amide C-N hydrolases, choloylglycine hydrolase family - - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH MHFCBNDO_00460 1423816.BACQ01000064_gene2468 1.42e-104 316.0 29Q1F@1|root,30B00@2|Bacteria,1U7BS@1239|Firmicutes,4IH72@91061|Bacilli,3F9AV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00461 543734.LCABL_04890 0.0 1137.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,4HAYH@91061|Bacilli,3F3QX@33958|Lactobacillaceae 91061|Bacilli S Myosin-crossreactive antigen l1n - 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA MHFCBNDO_00462 543734.LCABL_04900 7.24e-23 87.4 29QJ1@1|root,30BIK@2|Bacteria,1U86E@1239|Firmicutes,4II3Y@91061|Bacilli,3FAKU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00463 543734.LCABL_04910 4.1e-130 369.0 COG1309@1|root,COG1309@2|Bacteria,1VCF7@1239|Firmicutes,4IQ66@91061|Bacilli,3FBG6@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_8,TetR_N MHFCBNDO_00464 543734.LCABL_04920 2.1e-78 233.0 COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,4HKCN@91061|Bacilli,3F6YE@33958|Lactobacillaceae 91061|Bacilli S PTS system fructose IIA component dhaM GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05881 ko00561,map00561 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000,ko02000 - - - EIIA-man MHFCBNDO_00465 543734.LCABL_04930 4.95e-134 380.0 COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,4HGZY@91061|Bacilli,3F5VS@33958|Lactobacillaceae 91061|Bacilli S Dak2 dhaL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak2 MHFCBNDO_00466 543734.LCABL_04940 1.03e-242 667.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,4H9VS@91061|Bacilli,3F4F2@33958|Lactobacillaceae 91061|Bacilli G Dak1 domain dhaK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05878 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak1 MHFCBNDO_00467 543734.LCABL_04950 1.01e-99 289.0 COG1764@1|root,COG1764@2|Bacteria,1VY9T@1239|Firmicutes,4HXI7@91061|Bacilli,3F7CX@33958|Lactobacillaceae 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC MHFCBNDO_00468 543734.LCABL_04960 0.0 925.0 29Q2U@1|root,30B1F@2|Bacteria,1U7DD@1239|Firmicutes,4IH99@91061|Bacilli,3F9F1@33958|Lactobacillaceae 91061|Bacilli L Exonuclease - - - - - - - - - - - - RNase_T MHFCBNDO_00469 543734.LCABL_04970 4.23e-64 195.0 COG0640@1|root,COG0640@2|Bacteria,1VAK2@1239|Firmicutes,4HMC7@91061|Bacilli,3F704@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain yczG - - - - - - - - - - - HTH_20,HTH_5 MHFCBNDO_00470 543734.LCABL_04980 4.97e-255 702.0 COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,3F4X1@33958|Lactobacillaceae 91061|Bacilli EGP transporter yceJ - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1,Sugar_tr MHFCBNDO_00471 543734.LCABL_04990 4.89e-139 393.0 COG0640@1|root,COG0640@2|Bacteria,1V007@1239|Firmicutes,4HDXJ@91061|Bacilli,3F7E5@33958|Lactobacillaceae 91061|Bacilli K Transcriptional ydfF GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010288,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032791,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097063,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_20 MHFCBNDO_00472 543734.LCABL_05000 2.28e-138 390.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,3F5KA@33958|Lactobacillaceae 91061|Bacilli L glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco MHFCBNDO_00473 1423816.BACQ01000064_gene2484 3.1e-214 591.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,3F4EF@33958|Lactobacillaceae 91061|Bacilli G Fructose-1,6-bisphosphate aldolase, class II fba - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase MHFCBNDO_00474 543734.LCABL_05020 0.0 1149.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family cidC - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - iSB619.SA_RS13340 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N MHFCBNDO_00475 543734.LCABL_05030 5.8e-248 680.0 COG1680@1|root,COG1680@2|Bacteria,1UZUZ@1239|Firmicutes,4IPQ5@91061|Bacilli,3F969@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Beta-lactamase,DUF3471 MHFCBNDO_00476 568703.LGG_00530 3.81e-191 538.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,3F4XQ@33958|Lactobacillaceae 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family ykfB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N MHFCBNDO_00477 543734.LCABL_05040 3.17e-185 514.0 COG2227@1|root,COG2227@2|Bacteria,1UIIR@1239|Firmicutes,4ISJH@91061|Bacilli,3F5MJ@33958|Lactobacillaceae 91061|Bacilli H Protein of unknown function (DUF1698) - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 MHFCBNDO_00478 543734.LCABL_05050 3.85e-182 506.0 COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,3F4PK@33958|Lactobacillaceae 91061|Bacilli S peptidase C26 puuD - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 MHFCBNDO_00479 543734.LCABL_05060 0.0 890.0 COG0174@1|root,COG0174@2|Bacteria,1U0IB@1239|Firmicutes,4HTS7@91061|Bacilli 91061|Bacilli E Glutamine synthetase, catalytic domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N_2 MHFCBNDO_00480 543734.LCABL_05070 1.98e-281 768.0 COG2159@1|root,COG2159@2|Bacteria,1V9T6@1239|Firmicutes,4HKS1@91061|Bacilli 91061|Bacilli S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 MHFCBNDO_00481 543734.LCABL_05080 0.0 868.0 COG0531@1|root,COG0531@2|Bacteria,1V01X@1239|Firmicutes,4HVQJ@91061|Bacilli,3F7SQ@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease,AA_permease_2 MHFCBNDO_00482 543734.LCABL_05090 1.68e-98 286.0 COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4HH53@91061|Bacilli,3F7ID@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 MHFCBNDO_00483 543734.LCABL_05100 2.64e-208 575.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HAG6@91061|Bacilli,3FB4S@33958|Lactobacillaceae 91061|Bacilli S reductase - - - - - - - - - - - - Aldo_ket_red MHFCBNDO_00484 543734.LCABL_05180 0.0 983.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HDAQ@91061|Bacilli,3F75H@33958|Lactobacillaceae 91061|Bacilli GKT Mga helix-turn-helix domain - - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2 MHFCBNDO_00485 543734.LCABL_05190 7.58e-134 379.0 COG1961@1|root,COG1961@2|Bacteria,1V51N@1239|Firmicutes,4HDX2@91061|Bacilli,3F51V@33958|Lactobacillaceae 91061|Bacilli L Resolvase, N terminal domain tnpR1 - - - - - - - - - - - HTH_24,HTH_7,Resolvase MHFCBNDO_00486 543734.LCABL_05200 0.0 1769.0 COG2304@1|root,COG4932@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,1V87P@1239|Firmicutes,4HA8Y@91061|Bacilli,3F3PM@33958|Lactobacillaceae 91061|Bacilli M Cna protein B-type domain yvcC - - - - - - - - - - - Cna_B,VWA,VWA_2 MHFCBNDO_00487 543734.LCABL_05210 4.1e-162 454.0 COG4932@1|root,COG4932@2|Bacteria,1U7CB@1239|Firmicutes,4IH7P@91061|Bacilli,3F9CF@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - - MHFCBNDO_00488 543734.LCABL_05220 1.25e-236 651.0 COG4932@1|root,COG4932@2|Bacteria,1W6HP@1239|Firmicutes,4HZUT@91061|Bacilli,3F9E7@33958|Lactobacillaceae 91061|Bacilli M LPXTG cell wall anchor motif - - - - - - - - - - - - Gram_pos_anchor MHFCBNDO_00489 543734.LCABL_05230 6.11e-256 702.0 COG3764@1|root,COG3764@2|Bacteria,1V1RS@1239|Firmicutes,4HHRS@91061|Bacilli,3FCAC@33958|Lactobacillaceae 91061|Bacilli M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase MHFCBNDO_00490 543734.LCABL_05240 4.78e-164 460.0 COG1131@1|root,COG1131@2|Bacteria,1TRTC@1239|Firmicutes,4HG0J@91061|Bacilli,3F59T@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities XK27_12140 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_00491 543734.LCABL_05250 0.0 1028.0 28IHZ@1|root,2Z8J5@2|Bacteria,1TQV6@1239|Firmicutes,4HPC9@91061|Bacilli,3F5NC@33958|Lactobacillaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - MHFCBNDO_00492 543734.LCABL_05260 9.02e-163 456.0 COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,4HHWT@91061|Bacilli,3F536@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein, C terminal - - - ko:K20488 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C MHFCBNDO_00493 543734.LCABL_05270 7.26e-253 694.0 COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,4HBC0@91061|Bacilli,3F4NF@33958|Lactobacillaceae 91061|Bacilli T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K20487 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA MHFCBNDO_00494 543734.LCABL_05290 4.81e-181 506.0 COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,4HD67@91061|Bacilli,3F5Y2@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran MHFCBNDO_00495 543734.LCABL_05300 6.98e-265 726.0 28IVE@1|root,2Z8TU@2|Bacteria,1UYXD@1239|Firmicutes,4HMX1@91061|Bacilli,3F500@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 MHFCBNDO_00496 543734.LCABL_05310 3.41e-119 343.0 2CZFI@1|root,30A49@2|Bacteria,1U667@1239|Firmicutes,4IFWD@91061|Bacilli,3F761@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00497 543734.LCABL_05320 0.0 3336.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,3F3M5@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase S8 family prtP - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - PA,Peptidase_S8,SLAP,fn3_5 MHFCBNDO_00498 543734.LCABL_05330 0.0 2992.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,3F3M5@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase S8 family prtP - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - PA,Peptidase_S8,SLAP,fn3_5 MHFCBNDO_00499 543734.LCABL_05340 0.0 1669.0 COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli,3F3UH@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 MHFCBNDO_00500 543734.LCABL_05350 0.0 952.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HBIP@91061|Bacilli,3FCAH@33958|Lactobacillaceae 91061|Bacilli E amino acid ycaM - - - - - - - - - - - AA_permease_2 MHFCBNDO_00501 543734.LCABL_05360 1.66e-117 336.0 COG3477@1|root,COG3477@2|Bacteria,1VX0K@1239|Firmicutes,4HX2R@91061|Bacilli,3F6A5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1440) - - - ko:K08996 - - - - ko00000 - - - DUF1440 MHFCBNDO_00502 543734.LCABL_05370 7.85e-210 580.0 COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HFSV@91061|Bacilli,3F48I@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate MHFCBNDO_00503 1423732.BALS01000043_gene2705 4.66e-206 570.0 COG1082@1|root,COG1082@2|Bacteria,1TT50@1239|Firmicutes,4HCNS@91061|Bacilli,3F5RA@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 MHFCBNDO_00504 1423816.BACQ01000064_gene2507 1.26e-180 504.0 COG1028@1|root,COG1028@2|Bacteria,1TRFT@1239|Firmicutes,4HCX7@91061|Bacilli,3F4HT@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 MHFCBNDO_00505 543734.LCABL_05410 1.78e-210 582.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,3F5MZ@33958|Lactobacillaceae 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N MHFCBNDO_00506 543734.LCABL_05420 2.58e-274 752.0 COG0477@1|root,COG0477@2|Bacteria,1TS50@1239|Firmicutes,4HNF2@91061|Bacilli,3FBTT@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 MHFCBNDO_00507 543734.LCABL_05430 2.35e-212 587.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,3F4WM@33958|Lactobacillaceae 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N MHFCBNDO_00508 543734.LCABL_05440 2.74e-206 569.0 COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli,3F5CA@33958|Lactobacillaceae 91061|Bacilli E Transfers an acetyl group from acetyl-CoA to metA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS MHFCBNDO_00509 543734.LCABL_05450 2.2e-222 613.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,3F4VD@33958|Lactobacillaceae 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP MHFCBNDO_00510 1423724.BAMM01000001_gene101 1.52e-24 101.0 28WK8@1|root,32UJK@2|Bacteria,1VDM0@1239|Firmicutes,4HN9X@91061|Bacilli,3FBAY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00512 1423816.BACQ01000064_gene2513 9.15e-285 777.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HA65@91061|Bacilli,3F3NJ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family int3 - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase MHFCBNDO_00517 543734.LCABL_05530 4e-172 479.0 29QKX@1|root,30BKI@2|Bacteria,1U8A0@1239|Firmicutes,4II7Y@91061|Bacilli,3FAR9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00518 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00519 1423732.BALS01000070_gene2074 2.33e-25 100.0 COG2856@1|root,COG2856@2|Bacteria,1W1K0@1239|Firmicutes,4I17Z@91061|Bacilli 91061|Bacilli E Zn peptidase - - - - - - - - - - - - Peptidase_M78 MHFCBNDO_00520 543734.LCABL_05550 1.51e-80 238.0 COG1396@1|root,COG1396@2|Bacteria,1VEP9@1239|Firmicutes,4HPCR@91061|Bacilli,3F871@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_26,HTH_3 MHFCBNDO_00523 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00524 543734.LCABL_05570 8.44e-43 146.0 28IYH@1|root,2Z8W7@2|Bacteria,1V8EG@1239|Firmicutes,4HJXX@91061|Bacilli 91061|Bacilli S Protein of unknown function (Hypoth_ymh) ps305 - - - - - - - - - - - Hypoth_Ymh MHFCBNDO_00525 543734.LCABL_05580 2.14e-177 494.0 COG3646@1|root,COG3646@2|Bacteria,1VEBK@1239|Firmicutes,4IR34@91061|Bacilli,3FBM1@33958|Lactobacillaceae 91061|Bacilli S ORF6N domain - - - - - - - - - - - - ORF6C,ORF6N MHFCBNDO_00526 1423816.BACQ01000064_gene2520 1.66e-59 182.0 2AESZ@1|root,314PW@2|Bacteria,1VQHP@1239|Firmicutes,4HZNT@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF1883) - - - - - - - - - - - - DUF1883 MHFCBNDO_00532 1423816.BACQ01000064_gene2523 7.76e-181 503.0 COG3935@1|root,COG3935@2|Bacteria,1VHK1@1239|Firmicutes,4HQY7@91061|Bacilli,3FCF5@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain - - - - - - - - - - - - DnaB_2,HTH_36 MHFCBNDO_00533 543734.LCABL_05660 2.94e-198 549.0 COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,4HH4U@91061|Bacilli,3F6BK@33958|Lactobacillaceae 91061|Bacilli L IstB-like ATP binding protein pi346 - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 MHFCBNDO_00535 1423816.BACQ01000064_gene2526 1.56e-93 273.0 2BZYB@1|root,331KR@2|Bacteria,1VFNJ@1239|Firmicutes,4HPGT@91061|Bacilli,3F7VM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00536 1423816.BACQ01000064_gene2527 1.75e-171 479.0 28PQ6@1|root,2ZCCB@2|Bacteria,1V1NK@1239|Firmicutes,4HGG6@91061|Bacilli,3F6J4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00538 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00539 543734.LCABL_05720 4.76e-105 303.0 2DCNS@1|root,2ZESF@2|Bacteria,1W51N@1239|Firmicutes,4I1NU@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00541 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00542 543734.LCABL_03570 9.52e-240 659.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HDM3@91061|Bacilli,3F3UG@33958|Lactobacillaceae 91061|Bacilli L PFAM Integrase, catalytic core - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve MHFCBNDO_00543 1423816.BACQ01000065_gene2528 0.000324 42.4 COG3237@1|root,COG3237@2|Bacteria,1UQWF@1239|Firmicutes,4HS6A@91061|Bacilli,3F8HV@33958|Lactobacillaceae 91061|Bacilli S CsbD-like - - - - - - - - - - - - CsbD MHFCBNDO_00545 543734.LCABL_05760 4.73e-205 566.0 2C1BV@1|root,33HNE@2|Bacteria,1VQQP@1239|Firmicutes,4HWNS@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - GcrA MHFCBNDO_00546 1423816.BACQ01000026_gene949 3.44e-64 199.0 2C1BV@1|root,33HNE@2|Bacteria,1VQQP@1239|Firmicutes,4HWNS@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00547 543734.LCABL_05780 8.29e-74 221.0 2BWYP@1|root,30AJY@2|Bacteria,1U6SS@1239|Firmicutes,4IGKB@91061|Bacilli,3F8F9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00548 1423816.BACQ01000066_gene2531 2.11e-69 209.0 COG2963@1|root,COG2963@2|Bacteria,1VQ03@1239|Firmicutes,4HS9H@91061|Bacilli,3F77N@33958|Lactobacillaceae 91061|Bacilli L 4.5 Transposon and IS - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 MHFCBNDO_00549 543734.LCABL_05800 2.5e-174 486.0 COG2963@1|root,COG2963@2|Bacteria,1V1QC@1239|Firmicutes,4HH7E@91061|Bacilli,3F65F@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain - - - - - - - - - - - - HTH_28,HTH_Tnp_1 MHFCBNDO_00550 543734.LCABL_05810 1e-214 592.0 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,4HD6M@91061|Bacilli,3F43M@33958|Lactobacillaceae 91061|Bacilli L hmm pf00665 - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve MHFCBNDO_00551 1423816.BACQ01000066_gene2535 1.6e-199 553.0 COG2801@1|root,COG2801@2|Bacteria,1VSY9@1239|Firmicutes,4HUYS@91061|Bacilli,3F563@33958|Lactobacillaceae 91061|Bacilli L 4.5 Transposon and IS - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve MHFCBNDO_00555 1423732.BALS01000054_gene2738 6.78e-42 137.0 2C3WB@1|root,33NQV@2|Bacteria,1VQ12@1239|Firmicutes,4HSYA@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00556 543734.LCABL_05870 2.75e-257 710.0 2EG0H@1|root,339SH@2|Bacteria,1VP01@1239|Firmicutes,4HS1I@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00557 1423816.BACQ01000066_gene2540 1.44e-298 823.0 COG4932@1|root,COG4932@2|Bacteria,1V9ZD@1239|Firmicutes,4ITN8@91061|Bacilli 91061|Bacilli M Domain of unknown function (DUF5011) - - - - - - - - - - - - DUF5011 MHFCBNDO_00560 543734.LCABL_05910 0.0 1482.0 COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,4H9ZN@91061|Bacilli,3F4S3@33958|Lactobacillaceae 91061|Bacilli U TraM recognition site of TraD and TraG - - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf MHFCBNDO_00561 543734.LCABL_05920 0.0 1035.0 COG3266@1|root,COG3266@2|Bacteria,1TSNJ@1239|Firmicutes,4HEFK@91061|Bacilli 91061|Bacilli S domain, Protein - - - - - - - - - - - - - MHFCBNDO_00563 1423732.BALS01000054_gene2749 9.18e-137 387.0 2DME1@1|root,32QVI@2|Bacteria,1V94J@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - MHFCBNDO_00564 1423816.BACQ01000066_gene2547 0.0 1282.0 COG0433@1|root,COG0433@2|Bacteria,1W186@1239|Firmicutes,4HA4T@91061|Bacilli,3F6HE@33958|Lactobacillaceae 91061|Bacilli S COG0433 Predicted ATPase - - - - - - - - - - - - DUF87 MHFCBNDO_00565 543734.LCABL_05960 1.77e-237 653.0 COG0739@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria 2|Bacteria M cysteine-type peptidase activity - - - ko:K21471,ko:K21472 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60,Peptidase_M23 MHFCBNDO_00572 1423732.BALS01000076_gene2137 4.89e-283 775.0 COG0790@1|root,COG0790@2|Bacteria,1UHSY@1239|Firmicutes,4IS8P@91061|Bacilli,3F8F0@33958|Lactobacillaceae 91061|Bacilli S COG0790 FOG TPR repeat, SEL1 subfamily - - - - - - - - - - - - - MHFCBNDO_00574 1423732.BALS01000076_gene2135 0.0 949.0 COG0358@1|root,COG4227@1|root,COG0358@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,4HKTX@91061|Bacilli,3F8MI@33958|Lactobacillaceae 91061|Bacilli L Protein of unknown function (DUF3991) - - - - - - - - - - - - DUF3991,Toprim_2 MHFCBNDO_00575 1423816.BACQ01000066_gene2557 1.5e-205 570.0 2DUJA@1|root,33QY7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - MHFCBNDO_00576 543734.LCABL_06080 1.97e-84 249.0 2ED72@1|root,3373P@2|Bacteria,1W17P@1239|Firmicutes,4HXZS@91061|Bacilli,3FADZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00577 1423816.BACQ01000066_gene2559 2.45e-23 89.0 293FZ@1|root,2ZQYB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - MHFCBNDO_00578 1423732.BALS01000076_gene2132 1.03e-100 292.0 2DUJT@1|root,33R01@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - MHFCBNDO_00580 543734.LCABL_06130 9.59e-101 292.0 2F273@1|root,33V59@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - MHFCBNDO_00581 1423732.BALS01000076_gene2129 1.49e-198 551.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HK7D@91061|Bacilli,3FC9V@33958|Lactobacillaceae 91061|Bacilli F DNA/RNA non-specific endonuclease - - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 MHFCBNDO_00583 1033837.WANG_1733 1.26e-53 170.0 COG3293@1|root,COG3293@2|Bacteria,1VTEC@1239|Firmicutes,4HUXQ@91061|Bacilli,3F62D@33958|Lactobacillaceae 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 MHFCBNDO_00584 525318.HMPREF0497_2983 1.77e-76 227.0 COG3293@1|root,COG3293@2|Bacteria,1U5ZT@1239|Firmicutes,4IFNT@91061|Bacilli,3F6RW@33958|Lactobacillaceae 91061|Bacilli L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 MHFCBNDO_00586 568703.LGG_00456 0.0 1752.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 MHFCBNDO_00587 568703.LGG_00455 1.77e-56 175.0 298U1@1|root,30A4W@2|Bacteria,1U679@1239|Firmicutes,4IFXT@91061|Bacilli,3F78N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00588 1163671.JAGI01000002_gene3184 2.56e-10 62.4 COG2963@1|root,COG2963@2|Bacteria,1V3QZ@1239|Firmicutes,24PUE@186801|Clostridia 186801|Clostridia L Helix-turn-helix domain - - - - - - - - - - - - HTH_28 MHFCBNDO_00589 568703.LGG_00454 7.54e-205 566.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HBHG@91061|Bacilli,3F59Y@33958|Lactobacillaceae 91061|Bacilli L PFAM Integrase catalytic region - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve MHFCBNDO_00590 1423734.JCM14202_2816 1.02e-131 378.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,3F46G@33958|Lactobacillaceae 91061|Bacilli L Integrase core domain is18 - - - - - - - - - - - HTH_21,rve MHFCBNDO_00591 1074451.CRL705_1644 1.01e-51 163.0 COG2963@1|root,COG2963@2|Bacteria,1VIEV@1239|Firmicutes,4HJSC@91061|Bacilli,3F6X7@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 MHFCBNDO_00592 1423806.JCM15457_917 1.56e-45 161.0 2DKKN@1|root,309U4@2|Bacteria,1U5PU@1239|Firmicutes,4II78@91061|Bacilli,3FAQE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00593 944562.HMPREF9102_2131 3.7e-96 282.0 COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,4HCFF@91061|Bacilli,3F429@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed pinR1 - - - - - - - - - - - HTH_7,Resolvase MHFCBNDO_00594 334390.LAF_0675 2.24e-98 293.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve MHFCBNDO_00595 568703.LGG_00020 2.45e-128 371.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve MHFCBNDO_00596 568703.LGG_00450 0.0 1338.0 COG1195@1|root,COG3593@1|root,COG1195@2|Bacteria,COG3593@2|Bacteria,1UM78@1239|Firmicutes,4ITSY@91061|Bacilli,3F90U@33958|Lactobacillaceae 91061|Bacilli L AAA ATPase domain - - - ko:K07459 - - - - ko00000 - - - AAA_15 MHFCBNDO_00597 568703.LGG_00449 0.0 1197.0 COG0210@1|root,COG0210@2|Bacteria,1VH5W@1239|Firmicutes,4HUQM@91061|Bacilli 91061|Bacilli L UvrD/REP helicase N-terminal domain - - - - - - - - - - - - UvrD-helicase MHFCBNDO_00598 543734.LCABL_25440 1.04e-211 588.0 COG3410@1|root,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,4HBI0@91061|Bacilli,3F47M@33958|Lactobacillaceae 91061|Bacilli N Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075,GIY-YIG MHFCBNDO_00599 568703.LGG_00446 7.69e-134 379.0 2AYWY@1|root,31R2N@2|Bacteria,1UPXG@1239|Firmicutes,4IVCM@91061|Bacilli,3F66A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00600 568703.LGG_00444 0.0 1736.0 COG2304@1|root,COG4932@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,1V87P@1239|Firmicutes,4HA8Y@91061|Bacilli,3F3PM@33958|Lactobacillaceae 91061|Bacilli M Cna protein B-type domain yvcC - - - - - - - - - - - Cna_B,VWA,VWA_2 MHFCBNDO_00601 568703.LGG_00443 4.43e-163 457.0 COG4932@1|root,COG4932@2|Bacteria,1U7CB@1239|Firmicutes,4IH7P@91061|Bacilli,3F9CF@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - - MHFCBNDO_00602 568703.LGG_00442 1.1e-230 636.0 COG4932@1|root,COG4932@2|Bacteria,1W6HP@1239|Firmicutes,4HZUT@91061|Bacilli,3F9E7@33958|Lactobacillaceae 91061|Bacilli M LPXTG cell wall anchor motif - - - - - - - - - - - - Gram_pos_anchor MHFCBNDO_00603 568703.LGG_00441 5.91e-259 709.0 COG3764@1|root,COG3764@2|Bacteria,1V1RS@1239|Firmicutes,4HHRS@91061|Bacilli,3FCAC@33958|Lactobacillaceae 91061|Bacilli M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase MHFCBNDO_00604 1291743.LOSG293_590020 7.64e-88 258.0 COG3576@1|root,COG3576@2|Bacteria,1VW4G@1239|Firmicutes,4HW37@91061|Bacilli,3F6IW@33958|Lactobacillaceae 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx MHFCBNDO_00605 1423780.LOT_2232 3.45e-118 338.0 2DPIQ@1|root,3328X@2|Bacteria,1VFYC@1239|Firmicutes,4HNHQ@91061|Bacilli,3F7RW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - AP2 MHFCBNDO_00606 568703.LGG_00437 3.83e-61 187.0 COG0272@1|root,COG0272@2|Bacteria,1W4JC@1239|Firmicutes,4I09W@91061|Bacilli,3F83P@33958|Lactobacillaceae 91061|Bacilli L BRCA1 C Terminus (BRCT) domain - - - - - - - - - - - - BRCT MHFCBNDO_00607 568703.LGG_00436 1.14e-148 419.0 COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,4HCFF@91061|Bacilli,3F429@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed pinR1 - - - - - - - - - - - HTH_7,Resolvase MHFCBNDO_00608 543734.LCABL_06580 2.25e-64 198.0 28ZBI@1|root,2ZM3D@2|Bacteria,1W5K5@1239|Firmicutes,4I1Q6@91061|Bacilli,3F825@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 MHFCBNDO_00610 1074451.CRL705_1934 4e-110 316.0 COG0783@1|root,COG0783@2|Bacteria,1VCVJ@1239|Firmicutes,4HMBD@91061|Bacilli,3F5WI@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin MHFCBNDO_00611 1122149.BACN01000114_gene4 2.23e-196 545.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,3F46G@33958|Lactobacillaceae 91061|Bacilli L Integrase core domain is18 - - - - - - - - - - - HTH_21,rve MHFCBNDO_00612 1136177.KCA1_1226 1.23e-135 383.0 2AYWY@1|root,31R2N@2|Bacteria,1UPXG@1239|Firmicutes,4IVCM@91061|Bacilli,3F66A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00614 1074451.CRL705_1346 3.33e-23 89.4 COG2963@1|root,COG2963@2|Bacteria,1VIEV@1239|Firmicutes,4HJSC@91061|Bacilli,3F6X7@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 MHFCBNDO_00615 1122149.BACN01000114_gene4 2.07e-201 557.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,3F46G@33958|Lactobacillaceae 91061|Bacilli L Integrase core domain is18 - - - - - - - - - - - HTH_21,rve MHFCBNDO_00616 334390.LAF_0675 2.45e-245 673.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve MHFCBNDO_00617 543734.LCABL_06470 9.99e-208 575.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HDFE@91061|Bacilli,3FB4A@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE MHFCBNDO_00618 543734.LCABL_06480 6.44e-139 393.0 COG0431@1|root,COG0431@2|Bacteria,1TT2S@1239|Firmicutes,4HBQI@91061|Bacilli,3F544@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red MHFCBNDO_00619 543734.LCABL_06490 5.79e-307 836.0 COG0431@1|root,COG2461@1|root,COG0431@2|Bacteria,COG2461@2|Bacteria,1TPRA@1239|Firmicutes,4HDA5@91061|Bacilli,3F44U@33958|Lactobacillaceae 91061|Bacilli S reductase XK27_09615 - 1.5.1.36 ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 - R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 - - - FMN_red,PAS_10 MHFCBNDO_00620 525318.HMPREF0497_1019 3.67e-93 272.0 COG3576@1|root,COG3576@2|Bacteria,1VGE7@1239|Firmicutes,4HNE7@91061|Bacilli,3F6YB@33958|Lactobacillaceae 91061|Bacilli S pyridoxamine 5-phosphate - - - - - - - - - - - - Putative_PNPOx MHFCBNDO_00621 1423734.JCM14202_3874 3.94e-14 71.6 COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,4HER3@91061|Bacilli,3F4HK@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 MHFCBNDO_00623 543734.LCABL_21480 2.06e-161 452.0 COG3316@1|root,COG3316@2|Bacteria,1TTKR@1239|Firmicutes,4HCB4@91061|Bacilli,3F4NE@33958|Lactobacillaceae 91061|Bacilli L DDE domain tnp1216 - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 MHFCBNDO_00624 543734.LCABL_21290 5.16e-127 364.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 MHFCBNDO_00625 1423734.JCM14202_2841 2.14e-97 283.0 COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,4HH49@91061|Bacilli,3F6GQ@33958|Lactobacillaceae 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc MHFCBNDO_00626 1423734.JCM14202_2840 1.01e-73 221.0 2DMHQ@1|root,32RMG@2|Bacteria,1VB95@1239|Firmicutes,4HKKS@91061|Bacilli,3F7T6@33958|Lactobacillaceae 91061|Bacilli S Arsenical resistance operon trans-acting repressor ArsD - - - - - - - - - - - - ArsD MHFCBNDO_00627 1423734.JCM14202_2839 3.29e-297 812.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,3F5JS@33958|Lactobacillaceae 91061|Bacilli U Involved in arsenical resistance. Thought to form the channel of an arsenite pump arsB - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB MHFCBNDO_00628 1423732.BALS01000046_gene2609 5.12e-129 376.0 COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,4HBKG@91061|Bacilli,3F4XI@33958|Lactobacillaceae 91061|Bacilli D Anion-transporting ATPase arsA - 3.6.3.16 ko:K01551 - - - - ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 - - ArsA_ATPase MHFCBNDO_00629 543734.LCABL_21480 3.55e-162 454.0 COG3316@1|root,COG3316@2|Bacteria,1TTKR@1239|Firmicutes,4HCB4@91061|Bacilli,3F4NE@33958|Lactobacillaceae 91061|Bacilli L DDE domain tnp1216 - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 MHFCBNDO_00630 891391.LAC30SC_01325 9.14e-26 105.0 2DB9A@1|root,2Z7VI@2|Bacteria,1TT2W@1239|Firmicutes,4HMYR@91061|Bacilli,3F85D@33958|Lactobacillaceae 91061|Bacilli S Adenine-specific methyltransferase EcoRI - - - - - - - - - - - - EcoRI_methylase MHFCBNDO_00631 511437.Lbuc_0406 1.28e-145 411.0 COG4619@1|root,COG4619@2|Bacteria,1V3DQ@1239|Firmicutes,4HHGU@91061|Bacilli,3F4UY@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ybbL - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran MHFCBNDO_00632 511437.Lbuc_0405 2.42e-163 459.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,3F4P1@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0014) ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 MHFCBNDO_00633 1071400.LBUCD034_0440 4.27e-309 843.0 COG2211@1|root,COG2211@2|Bacteria,1VRWM@1239|Firmicutes,4HTJK@91061|Bacilli,3FBC3@33958|Lactobacillaceae 91061|Bacilli G MFS/sugar transport protein xylP - - - - - - - - - - - MFS_2 MHFCBNDO_00634 568703.LGG_00464 4.26e-159 449.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00635 568703.LGG_00435 1.13e-06 50.4 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00636 1246.JMEA01000020_gene753 1.76e-86 258.0 COG3316@1|root,COG3316@2|Bacteria,1TTKR@1239|Firmicutes,4HCB4@91061|Bacilli,4AXG2@81850|Leuconostocaceae 91061|Bacilli L DDE domain tnp1216 - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 MHFCBNDO_00637 203123.OEOE_0334 2.15e-77 229.0 COG3293@1|root,COG3293@2|Bacteria,1VW4T@1239|Firmicutes,4HWBF@91061|Bacilli,4AYJV@81850|Leuconostocaceae 91061|Bacilli L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 MHFCBNDO_00638 1138822.PL11_10530 6.35e-105 303.0 COG3293@1|root,COG3293@2|Bacteria,1VTEC@1239|Firmicutes,4HUXQ@91061|Bacilli,3F62D@33958|Lactobacillaceae 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 MHFCBNDO_00639 543734.LCABL_27970 0.0 958.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HBDR@91061|Bacilli,3F44S@33958|Lactobacillaceae 91061|Bacilli EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) choS - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC MHFCBNDO_00640 543734.LCABL_27960 6.07e-225 620.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,3F55H@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran MHFCBNDO_00641 543734.LCABL_27950 5.9e-315 858.0 COG1249@1|root,COG1249@2|Bacteria,1TS0Z@1239|Firmicutes,4HBYB@91061|Bacilli,3F3K2@33958|Lactobacillaceae 91061|Bacilli C Glutathione reductase gshR - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim MHFCBNDO_00642 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_00643 543734.LCABL_06610 2.49e-184 513.0 2DMZ9@1|root,32UJF@2|Bacteria,1V5SH@1239|Firmicutes,4HKAC@91061|Bacilli,3F68Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00644 543734.LCABL_06620 2.02e-269 738.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,3F3Y2@33958|Lactobacillaceae 91061|Bacilli E cystathionine mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP MHFCBNDO_00645 543734.LCABL_06630 2.79e-185 516.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,3F4MH@33958|Lactobacillaceae 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family tcyA - - ko:K02424 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 MHFCBNDO_00646 543734.LCABL_06640 2.87e-157 442.0 COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,4H9N1@91061|Bacilli,3F4QR@33958|Lactobacillaceae 91061|Bacilli E ABC transporter tcyB - - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1 MHFCBNDO_00647 1423816.BACQ01000040_gene1607 1.92e-44 160.0 29Q72@1|root,30B62@2|Bacteria,1U7KY@1239|Firmicutes,4IHI1@91061|Bacilli,3F9VZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00648 543734.LCABL_06660 0.0 880.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans MHFCBNDO_00649 543734.LCABL_06680 4.64e-151 425.0 2DDU7@1|root,2ZJAU@2|Bacteria,1UM02@1239|Firmicutes 1239|Firmicutes S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL MHFCBNDO_00650 543734.LCABL_06690 2.01e-224 620.0 COG4072@1|root,COG4072@2|Bacteria,1VCXS@1239|Firmicutes,4HKJG@91061|Bacilli,3F5HA@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein - - - - - - - - - - - - DUF3324,DUF916 MHFCBNDO_00651 543734.LCABL_06700 1.78e-58 183.0 2AIBJ@1|root,318SM@2|Bacteria,1U7ZW@1239|Firmicutes,4IHXA@91061|Bacilli,3FAD9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Gram_pos_anchor MHFCBNDO_00652 543734.LCABL_06710 0.0 1292.0 COG4886@1|root,COG4886@2|Bacteria,1UVV2@1239|Firmicutes,4I2C5@91061|Bacilli,3F806@33958|Lactobacillaceae 91061|Bacilli S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - WxL MHFCBNDO_00653 543734.LCABL_06730 1.66e-154 435.0 2DDU7@1|root,2ZJAU@2|Bacteria 2|Bacteria S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL MHFCBNDO_00654 543734.LCABL_06740 4.46e-74 222.0 29QPU@1|root,30BPI@2|Bacteria,1U8F4@1239|Firmicutes,4IID0@91061|Bacilli,3FAWZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00655 543734.LCABL_06750 1.28e-140 400.0 COG5492@1|root,COG5492@2|Bacteria,1W54S@1239|Firmicutes,4IF30@91061|Bacilli,3F5H0@33958|Lactobacillaceae 91061|Bacilli N WxL domain surface cell wall-binding - - - - - - - - - - - - WxL MHFCBNDO_00656 543734.LCABL_06760 0.0 1186.0 COG4886@1|root,COG4886@2|Bacteria,1UVV3@1239|Firmicutes,4I2C6@91061|Bacilli,3F8E0@33958|Lactobacillaceae 91061|Bacilli S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - WxL MHFCBNDO_00657 543734.LCABL_06770 6.94e-225 621.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family yicL - - - - - - - - - - - EamA MHFCBNDO_00658 543734.LCABL_06780 0.0 1085.0 28HMX@1|root,2Z7WB@2|Bacteria,1TPJG@1239|Firmicutes,4HBRI@91061|Bacilli,3F6T9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00659 543734.LCABL_06790 3.03e-186 518.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCT1@91061|Bacilli,3F5PG@33958|Lactobacillaceae 91061|Bacilli V ABC transporter CcmA5 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_00660 543734.LCABL_06800 4.07e-114 328.0 COG4720@1|root,COG4720@2|Bacteria,1V52B@1239|Firmicutes,4HJY9@91061|Bacilli,3FBCH@33958|Lactobacillaceae 91061|Bacilli S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS MHFCBNDO_00661 543734.LCABL_06810 2.05e-189 526.0 COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli,3F3V7@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin MHFCBNDO_00662 543734.LCABL_06820 7.88e-211 582.0 COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,4HGHI@91061|Bacilli,3FB7R@33958|Lactobacillaceae 91061|Bacilli C Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR MHFCBNDO_00663 543734.LCABL_06830 0.0 1516.0 COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli,3F3VW@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 MHFCBNDO_00664 543734.LCABL_06850 0.0 1083.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein XK27_09600 - - ko:K06147,ko:K18891 ko02010,map02010 M00708 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 - - ABC_membrane,ABC_tran MHFCBNDO_00665 543734.LCABL_06860 0.0 1140.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147,ko:K18892 ko02010,map02010 M00708 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 - - ABC_membrane,ABC_tran MHFCBNDO_00666 543734.LCABL_06870 3.34e-286 783.0 COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli,3F4XT@33958|Lactobacillaceae 91061|Bacilli P Major Facilitator Superfamily oxlT - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 MHFCBNDO_00667 543734.LCABL_06880 1.56e-166 466.0 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli,3F62J@33958|Lactobacillaceae 91061|Bacilli K UTRA treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA MHFCBNDO_00668 543734.LCABL_06890 0.0 1129.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C MHFCBNDO_00669 543734.LCABL_06900 0.0 1217.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system treB - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC MHFCBNDO_00670 543734.LCABL_06910 1.51e-283 778.0 COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,4HBEC@91061|Bacilli,3FB7N@33958|Lactobacillaceae 91061|Bacilli U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) sstT - - ko:K07862 - - - - ko00000,ko02000 2.A.23.4 - - SDF MHFCBNDO_00671 543734.LCABL_06920 0.0 929.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 MHFCBNDO_00672 543734.LCABL_06930 1.13e-221 611.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F4MZ@33958|Lactobacillaceae 91061|Bacilli C lactate/malate dehydrogenase, alpha/beta C-terminal domain ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N MHFCBNDO_00673 543734.LCABL_06940 0.0 869.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,3F4DS@33958|Lactobacillaceae 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N MHFCBNDO_00674 1423732.BALS01000009_gene740 3.08e-43 140.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3F7RG@33958|Lactobacillaceae 91061|Bacilli K 'Cold-shock' DNA-binding domain cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD MHFCBNDO_00675 543734.LCABL_06970 5.77e-87 257.0 29PCC@1|root,30AAK@2|Bacteria,1U6ED@1239|Firmicutes,4IG65@91061|Bacilli,3F7QE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00676 543734.LCABL_06980 1.37e-99 289.0 COG1764@1|root,COG1764@2|Bacteria,1VBJ0@1239|Firmicutes,4HNBY@91061|Bacilli,3F664@33958|Lactobacillaceae 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC MHFCBNDO_00677 543734.LCABL_06990 0.0 963.0 COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,4HBFK@91061|Bacilli,3F53D@33958|Lactobacillaceae 91061|Bacilli S ABC transporter yjcA - - ko:K19350 ko02010,map02010 - - - ko00000,ko00001,ko01504,ko02000 3.A.1.121 - - ABC_tran,ABC_tran_Xtn MHFCBNDO_00678 543734.LCABL_07000 2.73e-147 414.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,3F521@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding ylbE - - - - - - - - - - - NAD_binding_10 MHFCBNDO_00680 543734.LCABL_07010 6.7e-203 561.0 COG0656@1|root,COG0656@2|Bacteria,1VSK5@1239|Firmicutes,4HT3F@91061|Bacilli,3FBX5@33958|Lactobacillaceae 91061|Bacilli S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red MHFCBNDO_00681 543734.LCABL_07020 3.61e-316 862.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yifK - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease MHFCBNDO_00682 543734.LCABL_07030 0.0 1078.0 29PJG@1|root,30AHM@2|Bacteria,1U6PG@1239|Firmicutes,4IGGF@91061|Bacilli,3F896@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3800) - - - - - - - - - - - - DUF3800 MHFCBNDO_00683 543734.LCABL_07040 0.0 1235.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter nhaK - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger MHFCBNDO_00684 543734.LCABL_07050 2.72e-78 234.0 2C5CN@1|root,2ZGHZ@2|Bacteria,1W5A8@1239|Firmicutes,4I240@91061|Bacilli,3F89I@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 MHFCBNDO_00685 543734.LCABL_07060 1.2e-95 279.0 COG3279@1|root,COG3279@2|Bacteria,1W04J@1239|Firmicutes,4HRMI@91061|Bacilli,3F6TA@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR MHFCBNDO_00686 543734.LCABL_07070 2.56e-190 530.0 COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,4HJK7@91061|Bacilli,3FCET@33958|Lactobacillaceae 91061|Bacilli V ABC-2 type transporter - - - ko:K11051 ko02010,map02010 M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1.130 - - ABC2_membrane,ABC2_membrane_3 MHFCBNDO_00687 543734.LCABL_07080 7.53e-208 575.0 COG1131@1|root,COG1131@2|Bacteria,1TPJE@1239|Firmicutes,4HB5U@91061|Bacilli,3F58G@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01990,ko:K11050 ko02010,map02010 M00254,M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.130 - - ABC_tran MHFCBNDO_00688 543734.LCABL_07090 2.21e-174 486.0 COG4814@1|root,COG4814@2|Bacteria,1VXHZ@1239|Firmicutes,4HX59@91061|Bacilli,3F75V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 MHFCBNDO_00689 543734.LCABL_07100 7.12e-158 443.0 COG3338@1|root,COG3338@2|Bacteria,1V16J@1239|Firmicutes,4HA62@91061|Bacilli,3F7DZ@33958|Lactobacillaceae 91061|Bacilli P Eukaryotic-type carbonic anhydrase cah - 4.2.1.1 ko:K01674 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Carb_anhydrase MHFCBNDO_00690 543734.LCABL_07110 1.06e-69 210.0 COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,4HKGZ@91061|Bacilli,3F6YC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0145 family ybjQ - - - - - - - - - - - YbjQ_1 MHFCBNDO_00691 543734.LCABL_07120 2.05e-203 564.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,3F3WU@33958|Lactobacillaceae 91061|Bacilli C nadph quinone reductase - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 MHFCBNDO_00692 543734.LCABL_07130 4.75e-316 860.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,3F3X1@33958|Lactobacillaceae 91061|Bacilli P ammonium transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp MHFCBNDO_00693 543734.LCABL_07140 3.97e-227 625.0 COG2837@1|root,COG2837@2|Bacteria,1UY9Y@1239|Firmicutes,4HACQ@91061|Bacilli,3F45Z@33958|Lactobacillaceae 91061|Bacilli P Peroxidase ywbN GO:0005575,GO:0005576 - ko:K07223,ko:K16301 - - - - ko00000,ko01000,ko02000 2.A.108.2.3 - iYO844.BSU38260 Dyp_perox,TAT_signal MHFCBNDO_00694 543734.LCABL_07150 1.23e-153 432.0 COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,4HHDI@91061|Bacilli,3FB83@33958|Lactobacillaceae 91061|Bacilli S MgtC family yqgG - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC MHFCBNDO_00695 543734.LCABL_07160 1.46e-149 426.0 COG2169@1|root,COG2169@2|Bacteria,1V4X2@1239|Firmicutes,4HIF5@91061|Bacilli,3F3Y8@33958|Lactobacillaceae 91061|Bacilli F DNA RNA non-specific endonuclease endA - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2,Endonuclease_NS MHFCBNDO_00698 1423816.BACQ01000063_gene2437 5.74e-106 310.0 COG1131@1|root,COG1131@2|Bacteria,1VA12@1239|Firmicutes,4HMB1@91061|Bacilli,3F6Q1@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_00703 543734.LCABL_07180 0.0 1081.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,3F3ZJ@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn MHFCBNDO_00704 543734.LCABL_07190 0.0 1075.0 COG0249@1|root,COG0249@2|Bacteria,1TPJP@1239|Firmicutes,4HD9G@91061|Bacilli,3F5Q9@33958|Lactobacillaceae 91061|Bacilli L ATPase domain of DNA mismatch repair MUTS family - - - - - - - - - - - - MutS_V MHFCBNDO_00705 543734.LCABL_07200 2.99e-144 405.0 COG1573@1|root,COG1573@2|Bacteria,1V1F8@1239|Firmicutes,4HFVS@91061|Bacilli,3F4WH@33958|Lactobacillaceae 91061|Bacilli L Uracil-DNA glycosylase ung2 - - - - - - - - - - - UDG MHFCBNDO_00706 543734.LCABL_07210 1.29e-168 471.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,3F4J6@33958|Lactobacillaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP MHFCBNDO_00707 1423816.BACQ01000077_gene2626 0.0 1040.0 COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,3F5BS@33958|Lactobacillaceae 91061|Bacilli C C-terminal domain of alpha-glycerophosphate oxidase glpD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 - R00846,R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C MHFCBNDO_00708 543734.LCABL_07240 0.0 1013.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,3F3WI@33958|Lactobacillaceae 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N MHFCBNDO_00709 1423732.BALS01000046_gene2619 8.48e-172 479.0 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,4HGSR@91061|Bacilli,3FBSG@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 MHFCBNDO_00710 543734.LCABL_07300 3.3e-282 771.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli,3F3Q9@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg MHFCBNDO_00711 543734.LCABL_07310 4.24e-247 677.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,3F3YF@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd MHFCBNDO_00712 543734.LCABL_07320 0.0 966.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli,3F4D8@33958|Lactobacillaceae 91061|Bacilli G UDP-glucose--hexose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf MHFCBNDO_00713 543734.LCABL_07330 3.41e-218 604.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,3F3PB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator msmR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 MHFCBNDO_00714 543734.LCABL_07340 5.83e-252 690.0 COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,4HADZ@91061|Bacilli,3F48R@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of alpha and beta anomers of maltose galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim MHFCBNDO_00717 543734.LCABL_07380 1.92e-101 295.0 COG1762@1|root,COG1762@2|Bacteria,1VBW9@1239|Firmicutes,4IR84@91061|Bacilli,3FBMU@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.204 ko:K20112 ko02060,map02060 M00807 R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5 - - PTS_EIIA_2 MHFCBNDO_00718 1423816.BACQ01000077_gene2635 5.42e-67 203.0 COG3414@1|root,COG3414@2|Bacteria,1VACD@1239|Firmicutes,4HKHR@91061|Bacilli,3F732@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.204 ko:K20113 ko02060,map02060 M00807 R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5 - - PTS_IIB MHFCBNDO_00719 543734.LCABL_07400 0.0 924.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HBJG@91061|Bacilli,3FCCG@33958|Lactobacillaceae 91061|Bacilli G PTS system sugar-specific permease component gatC - - ko:K20114 ko02060,map02060 M00807 R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5 - - EIIC-GAT MHFCBNDO_00720 543734.LCABL_07410 2.82e-36 122.0 29QNH@1|root,30BN4@2|Bacteria,1U8CP@1239|Firmicutes,4IIAN@91061|Bacilli,3FAUA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00721 543734.LCABL_07420 2.22e-160 449.0 28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,4HMHN@91061|Bacilli,3F6AW@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4867) - - - - - - - - - - - - DUF4867 MHFCBNDO_00722 543734.LCABL_07430 1.75e-225 621.0 COG1105@1|root,COG1105@2|Bacteria,1TR9H@1239|Firmicutes,4HAGR@91061|Bacilli,3F56E@33958|Lactobacillaceae 91061|Bacilli H pfkB family carbohydrate kinase lacC - 2.7.1.144 ko:K00917 ko00052,ko01100,map00052,map01100 - R03236 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB MHFCBNDO_00723 543734.LCABL_07440 4.19e-239 657.0 COG3684@1|root,COG3684@2|Bacteria,1TQRR@1239|Firmicutes,4HBS9@91061|Bacilli,3F3UA@33958|Lactobacillaceae 91061|Bacilli G Belongs to the aldolase LacD family lacD - 4.1.2.40 ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 - R01069 RC00438,RC00439 ko00000,ko00001,ko01000 - - - DeoC MHFCBNDO_00724 543734.LCABL_07450 1.3e-121 347.0 COG0698@1|root,COG0698@2|Bacteria,1U9Y4@1239|Firmicutes,4HE4C@91061|Bacilli,3F41M@33958|Lactobacillaceae 91061|Bacilli G Ribose/Galactose Isomerase lacB - 5.3.1.26 ko:K01819 ko00052,ko01100,map00052,map01100 - R03240 RC00376 ko00000,ko00001,ko01000 - - - LacAB_rpiB MHFCBNDO_00725 543734.LCABL_07460 3.58e-96 280.0 COG0698@1|root,COG0698@2|Bacteria,1V5VZ@1239|Firmicutes,4HJK6@91061|Bacilli,3F6CQ@33958|Lactobacillaceae 91061|Bacilli G Ribose/Galactose Isomerase lacA - 5.3.1.26 ko:K01819 ko00052,ko01100,map00052,map01100 - R03240 RC00376 ko00000,ko00001,ko01000 - - - LacAB_rpiB MHFCBNDO_00726 543734.LCABL_07470 4.13e-181 504.0 COG1349@1|root,COG1349@2|Bacteria,1V097@1239|Firmicutes,4HGA7@91061|Bacilli,3F5GM@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - ko:K02530 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR MHFCBNDO_00727 543734.LCABL_07480 3.73e-150 422.0 COG0546@1|root,COG0546@2|Bacteria,1V7U6@1239|Firmicutes,4HJ9I@91061|Bacilli,3F658@33958|Lactobacillaceae 91061|Bacilli S HAD hydrolase, family IA, variant - - - - - - - - - - - - HAD_2 MHFCBNDO_00728 543734.LCABL_07490 1.37e-271 743.0 COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli,3F4A9@33958|Lactobacillaceae 91061|Bacilli L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C MHFCBNDO_00729 543734.LCABL_07500 0.0 1650.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,3F3TE@33958|Lactobacillaceae 91061|Bacilli L Putative exonuclease SbcCD, C subunit sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C MHFCBNDO_00730 543734.LCABL_07510 6.8e-21 82.8 29PWB@1|root,30AUN@2|Bacteria,1U74I@1239|Firmicutes,4IGZ5@91061|Bacilli,3F8YT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00731 543734.LCABL_07530 7.42e-112 321.0 COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HPDH@91061|Bacilli,3F7DR@33958|Lactobacillaceae 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family hsp1 - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 MHFCBNDO_00733 543734.LCABL_07540 3.37e-271 743.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,3FCD0@33958|Lactobacillaceae 91061|Bacilli L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 MHFCBNDO_00734 543734.LCABL_07550 2.23e-191 530.0 COG0657@1|root,COG0657@2|Bacteria,1VEC5@1239|Firmicutes,4HKY6@91061|Bacilli,3F50A@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 MHFCBNDO_00735 543734.LCABL_07560 1.5e-156 439.0 COG2249@1|root,COG2249@2|Bacteria,1V4UF@1239|Firmicutes,4HIR3@91061|Bacilli,3F6XY@33958|Lactobacillaceae 91061|Bacilli S Flavodoxin-like fold yrkL - - - - - - - - - - - Flavodoxin_2 MHFCBNDO_00737 543734.LCABL_07580 1.83e-113 326.0 COG3247@1|root,COG3247@2|Bacteria,1VK2X@1239|Firmicutes,4HQFY@91061|Bacilli,3F7G9@33958|Lactobacillaceae 91061|Bacilli S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 MHFCBNDO_00738 543734.LCABL_07590 1.92e-153 430.0 COG4832@1|root,COG4832@2|Bacteria,1U5NN@1239|Firmicutes,4IFD7@91061|Bacilli,3F684@33958|Lactobacillaceae 91061|Bacilli S Psort location Cytoplasmic, score - - - - - - - - - - - - - MHFCBNDO_00739 543734.LCABL_07600 9.5e-199 550.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,3F3NA@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin MHFCBNDO_00740 543734.LCABL_07610 1.94e-251 690.0 29Q0Q@1|root,30AZ6@2|Bacteria,1U7AN@1239|Firmicutes,4IH5M@91061|Bacilli,3F980@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00742 543734.LCABL_07630 1.39e-149 421.0 COG2910@1|root,COG2910@2|Bacteria,1TZ3T@1239|Firmicutes,4HVUN@91061|Bacilli,3F5K7@33958|Lactobacillaceae 91061|Bacilli S NAD(P)H-binding - - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 MHFCBNDO_00743 543734.LCABL_07640 0.0 1544.0 COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,3F43A@33958|Lactobacillaceae 91061|Bacilli G hydrolase, family 3 bglB - 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C MHFCBNDO_00744 543734.LCABL_07660 3.06e-213 590.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F4MI@33958|Lactobacillaceae 91061|Bacilli S ABC transporter substrate binding protein XK27_00670 - - ko:K01989,ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind MHFCBNDO_00745 543734.LCABL_07680 5.43e-209 580.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F462@33958|Lactobacillaceae 91061|Bacilli S ABC transporter XK27_00670 - - ko:K01989,ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind MHFCBNDO_00746 543734.LCABL_07690 5.61e-207 575.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,3F40J@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family WQ51_06230 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 MHFCBNDO_00747 543734.LCABL_07700 3.37e-180 503.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,3F3NW@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein - - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran MHFCBNDO_00748 543734.LCABL_07710 1.17e-222 614.0 COG0604@1|root,COG0604@2|Bacteria,1TPGR@1239|Firmicutes,4HACF@91061|Bacilli,3F5R8@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N MHFCBNDO_00749 543734.LCABL_07720 0.0 1586.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F588@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus pacL3 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 MHFCBNDO_00750 543734.LCABL_07730 8.07e-233 640.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,3F3X7@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 2 ykcC - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 MHFCBNDO_00751 543734.LCABL_07740 0.0 1347.0 COG1807@1|root,COG1807@2|Bacteria,1TPGI@1239|Firmicutes,4HCEY@91061|Bacilli,3F5B1@33958|Lactobacillaceae 91061|Bacilli M Dolichyl-phosphate-mannose-protein mannosyltransferase ykcB - - - - - - - - - - - PMT_2 MHFCBNDO_00752 543734.LCABL_07750 3.08e-93 272.0 2DTIF@1|root,33KHD@2|Bacteria,1UIGW@1239|Firmicutes,4ISGW@91061|Bacilli,3F7X1@33958|Lactobacillaceae 91061|Bacilli S GtrA-like protein - - - - - - - - - - - - GtrA MHFCBNDO_00753 543734.LCABL_07760 3.91e-159 446.0 COG0745@1|root,COG0745@2|Bacteria,1V295@1239|Firmicutes,4HG3X@91061|Bacilli,3F3TH@33958|Lactobacillaceae 91061|Bacilli K cheY-homologous receiver domain ciaR - - ko:K14983 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C MHFCBNDO_00754 543734.LCABL_07770 3e-309 843.0 COG5002@1|root,COG5002@2|Bacteria,1TS5K@1239|Firmicutes,4H9Y1@91061|Bacilli,3F49T@33958|Lactobacillaceae 91061|Bacilli T His Kinase A (phosphoacceptor) domain ciaH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K14982 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA MHFCBNDO_00755 543734.LCABL_07780 2.42e-88 259.0 COG4918@1|root,COG4918@2|Bacteria,1VK6M@1239|Firmicutes,4HRFS@91061|Bacilli,3F7JD@33958|Lactobacillaceae 91061|Bacilli S Belongs to the HesB IscA family - - - - - - - - - - - - Fe-S_biosyn MHFCBNDO_00756 543734.LCABL_07790 0.0 940.0 COG2508@1|root,COG2508@2|Bacteria,1TRRH@1239|Firmicutes,4HQKK@91061|Bacilli,3F5KD@33958|Lactobacillaceae 91061|Bacilli QT PucR C-terminal helix-turn-helix domain - - - - - - - - - - - - HTH_30 MHFCBNDO_00757 543734.LCABL_07800 3.74e-207 572.0 COG4221@1|root,COG4221@2|Bacteria,1UI5T@1239|Firmicutes,4HI5J@91061|Bacilli,3FBSB@33958|Lactobacillaceae 91061|Bacilli S KR domain - - - - - - - - - - - - adh_short MHFCBNDO_00758 543734.LCABL_07810 1.92e-202 560.0 COG4689@1|root,COG4689@2|Bacteria,1VW7Z@1239|Firmicutes,4I17W@91061|Bacilli,3F5RQ@33958|Lactobacillaceae 91061|Bacilli Q Acetoacetate decarboxylase (ADC) adc - 4.1.1.4 ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 M00088 R01366 RC00040 ko00000,ko00001,ko00002,ko01000 - - - ADC MHFCBNDO_00759 543734.LCABL_07820 2.41e-156 438.0 COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HBVQ@91061|Bacilli,3F4H1@33958|Lactobacillaceae 91061|Bacilli C Nitroreductase family ydgI - - - - - - - - - - - Nitroreductase MHFCBNDO_00760 543734.LCABL_07830 8.76e-261 715.0 COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,4HAU5@91061|Bacilli,3F9FE@33958|Lactobacillaceae 91061|Bacilli C IMP dehydrogenase / GMP reductase domain lldD - 1.13.12.4 ko:K00467 ko00620,map00620 - R00319 RC01312 ko00000,ko00001,ko01000 - - - FMN_dh MHFCBNDO_00761 511437.Lbuc_0020 3.68e-136 400.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family sip - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase MHFCBNDO_00763 208596.CAR_c08860 9.62e-06 48.9 COG3655@1|root,COG3655@2|Bacteria 2|Bacteria K Transcriptional regulator - - - ko:K07727 - - - - ko00000,ko03000 - - - DUF739,HTH_26,HTH_3 MHFCBNDO_00765 1423816.BACQ01000022_gene757 1.91e-77 232.0 2BZQS@1|root,30A7Z@2|Bacteria,1U6B6@1239|Firmicutes,4IG2Q@91061|Bacilli,3F7HW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00766 568703.LGG_02889 1.67e-21 84.3 29QI2@1|root,30BHH@2|Bacteria,1U84R@1239|Firmicutes,4II26@91061|Bacilli,3FAIV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00767 543734.LCABL_30840 4.23e-33 114.0 29QP0@1|root,30BNN@2|Bacteria,1U8DG@1239|Firmicutes,4IIBE@91061|Bacilli,3FAV3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00768 1423732.BALS01000058_gene2818 5.2e-46 149.0 29QB8@1|root,30BAG@2|Bacteria,1U7TH@1239|Firmicutes,4IHQZ@91061|Bacilli,3FA5K@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00769 543734.LCABL_30860 1.1e-32 113.0 2AIKE@1|root,3192N@2|Bacteria,1U847@1239|Firmicutes,4II1N@91061|Bacilli,3FAIA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00770 568703.LGG_02893 1.2e-202 560.0 COG3598@1|root,COG3598@2|Bacteria,1VVT1@1239|Firmicutes,4ITNM@91061|Bacilli,3FBJ8@33958|Lactobacillaceae 91061|Bacilli L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - PriCT_1,Prim-Pol MHFCBNDO_00771 568703.LGG_02894 0.0 952.0 COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,4HCHZ@91061|Bacilli,3F4EZ@33958|Lactobacillaceae 91061|Bacilli S Virulence-associated protein E - - - - - - - - - - - - VirE MHFCBNDO_00772 568703.LGG_02895 9.8e-97 281.0 arCOG11762@1|root,30AWJ@2|Bacteria,1U772@1239|Firmicutes,4IH1W@91061|Bacilli,3F924@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00773 568703.LGG_02897 6.36e-103 298.0 COG3747@1|root,COG3747@2|Bacteria,1VJ8S@1239|Firmicutes,4HQ9R@91061|Bacilli,3F4WP@33958|Lactobacillaceae 91061|Bacilli L Phage terminase, small subunit terS - - - - - - - - - - - Terminase_4 MHFCBNDO_00774 568703.LGG_02898 0.0 1094.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,3F51U@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name terL - - - - - - - - - - - Terminase_1 MHFCBNDO_00775 568703.LGG_02899 6.06e-29 103.0 2BTIA@1|root,32NQT@2|Bacteria,1U8EJ@1239|Firmicutes,4IICE@91061|Bacilli,3FAWA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00776 568703.LGG_02900 1.02e-279 765.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,4HHWD@91061|Bacilli,3F42D@33958|Lactobacillaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal MHFCBNDO_00777 568703.LGG_02901 0.0 972.0 COG3740@1|root,COG4653@1|root,COG3740@2|Bacteria,COG4653@2|Bacteria,1TSYM@1239|Firmicutes,4HE4V@91061|Bacilli,3F5ZB@33958|Lactobacillaceae 91061|Bacilli S Phage capsid family - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78,Phage_capsid MHFCBNDO_00778 568703.LGG_02902 2.28e-63 193.0 28TB1@1|root,2ZIBE@2|Bacteria,1W1M4@1239|Firmicutes,4I0N3@91061|Bacilli 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 MHFCBNDO_00779 1196324.A374_08749 4.82e-18 80.1 2C6FI@1|root,2ZGHD@2|Bacteria,1W3UJ@1239|Firmicutes 1239|Firmicutes S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join MHFCBNDO_00781 511437.Lbuc_0020 3.68e-136 400.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family sip - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase MHFCBNDO_00783 208596.CAR_c08860 9.62e-06 48.9 COG3655@1|root,COG3655@2|Bacteria 2|Bacteria K Transcriptional regulator - - - ko:K07727 - - - - ko00000,ko03000 - - - DUF739,HTH_26,HTH_3 MHFCBNDO_00785 1423816.BACQ01000022_gene757 1.91e-77 232.0 2BZQS@1|root,30A7Z@2|Bacteria,1U6B6@1239|Firmicutes,4IG2Q@91061|Bacilli,3F7HW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00786 568703.LGG_02889 1.67e-21 84.3 29QI2@1|root,30BHH@2|Bacteria,1U84R@1239|Firmicutes,4II26@91061|Bacilli,3FAIV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00787 543734.LCABL_30840 4.23e-33 114.0 29QP0@1|root,30BNN@2|Bacteria,1U8DG@1239|Firmicutes,4IIBE@91061|Bacilli,3FAV3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00788 1423732.BALS01000058_gene2818 5.2e-46 149.0 29QB8@1|root,30BAG@2|Bacteria,1U7TH@1239|Firmicutes,4IHQZ@91061|Bacilli,3FA5K@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00789 543734.LCABL_30860 1.1e-32 113.0 2AIKE@1|root,3192N@2|Bacteria,1U847@1239|Firmicutes,4II1N@91061|Bacilli,3FAIA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00790 568703.LGG_02893 1.2e-202 560.0 COG3598@1|root,COG3598@2|Bacteria,1VVT1@1239|Firmicutes,4ITNM@91061|Bacilli,3FBJ8@33958|Lactobacillaceae 91061|Bacilli L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - PriCT_1,Prim-Pol MHFCBNDO_00791 568703.LGG_02894 0.0 952.0 COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,4HCHZ@91061|Bacilli,3F4EZ@33958|Lactobacillaceae 91061|Bacilli S Virulence-associated protein E - - - - - - - - - - - - VirE MHFCBNDO_00792 568703.LGG_02895 9.8e-97 281.0 arCOG11762@1|root,30AWJ@2|Bacteria,1U772@1239|Firmicutes,4IH1W@91061|Bacilli,3F924@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00793 568703.LGG_02897 4.14e-22 89.0 COG3747@1|root,COG3747@2|Bacteria,1VJ8S@1239|Firmicutes,4HQ9R@91061|Bacilli,3F4WP@33958|Lactobacillaceae 91061|Bacilli L Phage terminase, small subunit terS - - - - - - - - - - - Terminase_4 MHFCBNDO_00794 568703.LGG_02898 0.0 1094.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,3F51U@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name terL - - - - - - - - - - - Terminase_1 MHFCBNDO_00795 568703.LGG_02899 6.06e-29 103.0 2BTIA@1|root,32NQT@2|Bacteria,1U8EJ@1239|Firmicutes,4IICE@91061|Bacilli,3FAWA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00796 568703.LGG_02900 1.02e-279 765.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,4HHWD@91061|Bacilli,3F42D@33958|Lactobacillaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal MHFCBNDO_00797 568703.LGG_02901 0.0 972.0 COG3740@1|root,COG4653@1|root,COG3740@2|Bacteria,COG4653@2|Bacteria,1TSYM@1239|Firmicutes,4HE4V@91061|Bacilli,3F5ZB@33958|Lactobacillaceae 91061|Bacilli S Phage capsid family - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78,Phage_capsid MHFCBNDO_00798 568703.LGG_02902 2.28e-63 193.0 28TB1@1|root,2ZIBE@2|Bacteria,1W1M4@1239|Firmicutes,4I0N3@91061|Bacilli 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 MHFCBNDO_00799 1196324.A374_08749 4.82e-18 80.1 2C6FI@1|root,2ZGHD@2|Bacteria,1W3UJ@1239|Firmicutes 1239|Firmicutes S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join MHFCBNDO_00803 543734.LCABL_07860 2.98e-227 628.0 COG1476@1|root,COG1476@2|Bacteria,1V36C@1239|Firmicutes,4IT3D@91061|Bacilli,3F65G@33958|Lactobacillaceae 91061|Bacilli K DNA-binding helix-turn-helix protein - - - - - - - - - - - - HTH_3 MHFCBNDO_00804 543734.LCABL_07870 6.77e-77 229.0 COG1695@1|root,COG1695@2|Bacteria,1VA94@1239|Firmicutes,4HKJS@91061|Bacilli,3F6I1@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family - - - ko:K10947 - - - - ko00000,ko03000 - - - PadR MHFCBNDO_00805 543734.LCABL_07880 2.7e-62 191.0 COG4095@1|root,COG4095@2|Bacteria,1VBI9@1239|Firmicutes,4HMY5@91061|Bacilli,3F7IR@33958|Lactobacillaceae 91061|Bacilli S Sugar efflux transporter for intercellular exchange ygbF - - - - - - - - - - - MtN3_slv MHFCBNDO_00806 568703.LGG_00711 8.16e-54 169.0 2AVVX@1|root,31MPR@2|Bacteria,1U7Q2@1239|Firmicutes,4IHMD@91061|Bacilli,3FA04@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00807 543734.LCABL_07900 9.58e-244 669.0 COG0604@1|root,COG0604@2|Bacteria,1TRNC@1239|Firmicutes,4HATC@91061|Bacilli,3F48F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily - - 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 MHFCBNDO_00809 543734.LCABL_07910 2.67e-71 215.0 2BQ7I@1|root,32J28@2|Bacteria,1U7KB@1239|Firmicutes,4IHHD@91061|Bacilli,3F9V1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00810 543734.LCABL_07920 1.79e-104 303.0 2CCJZ@1|root,303JM@2|Bacteria,1U58T@1239|Firmicutes,4IF00@91061|Bacilli,3F565@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00811 543734.LCABL_07930 1.93e-265 728.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3F418@33958|Lactobacillaceae 91061|Bacilli S AI-2E family transporter XK27_05220 - - - - - - - - - - - AI-2E_transport MHFCBNDO_00812 568703.LGG_00716 1.58e-33 115.0 29QE7@1|root,30BDI@2|Bacteria,1U7YK@1239|Firmicutes,4IHVZ@91061|Bacilli,3FABT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00813 543734.LCABL_07950 9.86e-146 410.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,3F3JG@33958|Lactobacillaceae 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 MHFCBNDO_00814 568703.LGG_00718 2.18e-60 191.0 29Q6R@1|root,30B5R@2|Bacteria,1U7KG@1239|Firmicutes,4IHHI@91061|Bacilli,3F9VA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00815 543734.LCABL_07970 1.71e-213 591.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HB48@91061|Bacilli,3FCFH@33958|Lactobacillaceae 91061|Bacilli S Transporter, auxin efflux carrier (AEC) family protein mleP2 - - ko:K07088 - - - - ko00000 - - - Mem_trans MHFCBNDO_00816 568703.LGG_00720 1.45e-116 337.0 COG1853@1|root,COG1853@2|Bacteria,1V999@1239|Firmicutes,4HK1X@91061|Bacilli,3FBBG@33958|Lactobacillaceae 91061|Bacilli S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct MHFCBNDO_00817 1423732.BALS01000001_gene1300 9.67e-91 279.0 29Q3E@1|root,30B22@2|Bacteria,1U7EG@1239|Firmicutes,4IHAC@91061|Bacilli,3F9H2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00818 543734.LCABL_08020 6.56e-131 371.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,3F4KQ@33958|Lactobacillaceae 91061|Bacilli H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family fthC GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig MHFCBNDO_00819 543734.LCABL_08030 1.7e-81 241.0 COG3189@1|root,COG3189@2|Bacteria,1VABH@1239|Firmicutes,4HKI2@91061|Bacilli,3F715@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function, DUF488 yeaO - - - - - - - - - - - DUF488 MHFCBNDO_00820 543734.LCABL_08040 2.2e-223 615.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,3F5FV@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein - - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA MHFCBNDO_00821 543734.LCABL_08050 1.7e-201 558.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli,3F5D2@33958|Lactobacillaceae 91061|Bacilli K LysR family mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - HTH_1,LysR_substrate MHFCBNDO_00822 543734.LCABL_08060 0.0 1096.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4HBF1@91061|Bacilli,3F3RH@33958|Lactobacillaceae 91061|Bacilli C Malic enzyme mleS - 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 - R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 - - - Malic_M,malic MHFCBNDO_00823 543734.LCABL_08070 3.58e-217 601.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HDX5@91061|Bacilli,3F3S0@33958|Lactobacillaceae 91061|Bacilli S Sodium Bile acid symporter family mleP - - ko:K07088 - - - - ko00000 - - - Mem_trans MHFCBNDO_00824 543734.LCABL_08080 8.23e-117 334.0 COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,3F5VY@33958|Lactobacillaceae 91061|Bacilli O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin MHFCBNDO_00825 543734.LCABL_08090 4.6e-113 324.0 COG0716@1|root,COG0716@2|Bacteria 2|Bacteria C FMN binding - - - - - - - - - - - - Flavodoxin_5 MHFCBNDO_00826 543734.LCABL_08120 0.0 1204.0 COG1164@1|root,COG1164@2|Bacteria,1TR7D@1239|Firmicutes,4HA0P@91061|Bacilli,3F3R3@33958|Lactobacillaceae 91061|Bacilli E Oligopeptidase F pepF - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N MHFCBNDO_00827 543734.LCABL_08130 3.86e-78 232.0 29Q7J@1|root,30B6K@2|Bacteria,1U7MR@1239|Firmicutes,4IHIY@91061|Bacilli,3F9X3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00828 543734.LCABL_08140 3.81e-170 475.0 COG1028@1|root,COG1028@2|Bacteria,1V7U7@1239|Firmicutes,4HIUT@91061|Bacilli,3F491@33958|Lactobacillaceae 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short MHFCBNDO_00829 543734.LCABL_08150 1.16e-106 307.0 COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,3F68C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the NDK family ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK MHFCBNDO_00830 543734.LCABL_08160 0.0 1433.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9ZI@91061|Bacilli,3F4Y1@33958|Lactobacillaceae 91061|Bacilli P E1-E2 ATPase yfgQ - - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase MHFCBNDO_00831 543734.LCABL_08170 7.43e-229 629.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 MHFCBNDO_00832 568703.LGG_00737 1.69e-58 182.0 29Q8P@1|root,30B7R@2|Bacteria,1U7PN@1239|Firmicutes,4IHKZ@91061|Bacilli,3F9ZK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00833 543734.LCABL_08190 1.4e-121 347.0 COG1670@1|root,COG1670@2|Bacteria,1UM04@1239|Firmicutes,4ITN9@91061|Bacilli,3FBX6@33958|Lactobacillaceae 91061|Bacilli J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - - MHFCBNDO_00834 543734.LCABL_08200 1.14e-255 703.0 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,3F3QK@33958|Lactobacillaceae 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family napA - - - - - - - - - - - Na_H_Exchanger MHFCBNDO_00835 543734.LCABL_08210 7.46e-157 440.0 COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,4HQUJ@91061|Bacilli,3FCA0@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase XK27_05175 - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 MHFCBNDO_00836 543734.LCABL_08220 2.24e-101 294.0 COG1846@1|root,COG1846@2|Bacteria,1V6TR@1239|Firmicutes,4HXA8@91061|Bacilli,3F66M@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 MHFCBNDO_00837 543734.LCABL_08230 2.4e-231 635.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,FSH1,Hydrolase_4 MHFCBNDO_00838 543734.LCABL_08240 3.83e-109 314.0 COG1780@1|root,COG1780@2|Bacteria,1V71V@1239|Firmicutes,4HIW7@91061|Bacilli,3F6JF@33958|Lactobacillaceae 91061|Bacilli F Belongs to the NrdI family nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI MHFCBNDO_00839 543734.LCABL_08250 3.58e-199 551.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HACK@91061|Bacilli,3F4XF@33958|Lactobacillaceae 91061|Bacilli S reductase dkgB - - - - - - - - - - - Aldo_ket_red MHFCBNDO_00840 543734.LCABL_08260 4.76e-201 559.0 29Q1I@1|root,30B03@2|Bacteria,1U7BX@1239|Firmicutes,4IH77@91061|Bacilli,3F9BB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00841 543734.LCABL_08270 1.02e-197 548.0 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 MHFCBNDO_00842 543734.LCABL_08280 7.76e-152 427.0 COG2323@1|root,COG2323@2|Bacteria,1TPNF@1239|Firmicutes,4HF15@91061|Bacilli,3F4F3@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF421) yviA - - - - - - - - - - - DUF421 MHFCBNDO_00843 543734.LCABL_08290 1.28e-33 121.0 2C9NT@1|root,32ZGB@2|Bacteria,1VG8C@1239|Firmicutes,4HN0V@91061|Bacilli,3F749@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3290) - - - - - - - - - - - - DUF3290 MHFCBNDO_00844 543734.LCABL_08300 5.92e-284 774.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,3F49P@33958|Lactobacillaceae 91061|Bacilli E methionine synthase, vitamin-B12 independent metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 MHFCBNDO_00845 543734.LCABL_08310 1.69e-112 322.0 COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,3F4W2@33958|Lactobacillaceae 91061|Bacilli H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS MHFCBNDO_00846 543734.LCABL_08320 1.3e-136 387.0 COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,4HJDU@91061|Bacilli,3FCEX@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein yjbF - - - - - - - - - - - SNARE_assoc MHFCBNDO_00847 543734.LCABL_08330 8.46e-133 377.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,3F42W@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N MHFCBNDO_00848 543734.LCABL_08340 4.54e-241 662.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,3F47S@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N MHFCBNDO_00849 543734.LCABL_08350 7.52e-263 719.0 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,3F3VG@33958|Lactobacillaceae 91061|Bacilli J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth MHFCBNDO_00850 543734.LCABL_08360 3.46e-289 788.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,3F43F@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT MHFCBNDO_00851 543734.LCABL_08370 5.25e-87 256.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,3F7EY@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC MHFCBNDO_00852 543734.LCABL_08380 0.0 1708.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli,3F3RN@33958|Lactobacillaceae 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH MHFCBNDO_00853 543734.LCABL_08390 2.06e-150 423.0 COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HI7T@91061|Bacilli,3FBMJ@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix diphteria tox regulatory element mntR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA MHFCBNDO_00854 543734.LCABL_08400 0.0 1002.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,3F48G@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N MHFCBNDO_00855 543734.LCABL_08410 4.19e-263 721.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,3F44N@33958|Lactobacillaceae 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH MHFCBNDO_00856 543734.LCABL_08420 1.13e-307 839.0 COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli,3F41P@33958|Lactobacillaceae 91061|Bacilli K DRTGG domain ytoI - - - - - - - - - - - 4HBT,CBS,DRTGG,GntR,HTH_24 MHFCBNDO_00857 543734.LCABL_08430 3.03e-229 631.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F4FC@33958|Lactobacillaceae 91061|Bacilli S DHHA1 domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 MHFCBNDO_00858 543734.LCABL_08440 0.0 866.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,3F4FQ@33958|Lactobacillaceae 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C MHFCBNDO_00859 543734.LCABL_08450 4.44e-223 615.0 295Z0@1|root,2ZT9T@2|Bacteria,1UJCK@1239|Firmicutes,4IT5A@91061|Bacilli,3F63F@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00860 543734.LCABL_08460 0.0 1748.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,3F3QS@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD MHFCBNDO_00862 1423732.BALS01000001_gene1354 4.89e-58 179.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,3F7EG@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 MHFCBNDO_00863 543734.LCABL_08480 2.67e-96 280.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,3F6NI@33958|Lactobacillaceae 91061|Bacilli J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX MHFCBNDO_00864 543734.LCABL_08490 1.3e-69 210.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,3F6X3@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 MHFCBNDO_00865 543734.LCABL_08500 2.84e-48 154.0 COG3027@1|root,COG3027@2|Bacteria,1VFZS@1239|Firmicutes,4HP4T@91061|Bacilli,3F7ZA@33958|Lactobacillaceae 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division - - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA MHFCBNDO_00866 543734.LCABL_08510 1.89e-119 342.0 COG1286@1|root,COG1286@2|Bacteria,1V7U0@1239|Firmicutes,4HIUU@91061|Bacilli,3F6FV@33958|Lactobacillaceae 91061|Bacilli S Colicin V production protein cvpA - - - - - - - - - - - Colicin_V MHFCBNDO_00867 543734.LCABL_08520 0.0 1487.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,3F4DX@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr MHFCBNDO_00868 543734.LCABL_08530 3.64e-70 211.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F6Y3@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin MHFCBNDO_00869 543734.LCABL_08540 1.04e-27 100.0 2DKST@1|root,30APB@2|Bacteria,1U6XZ@1239|Firmicutes,4IGS5@91061|Bacilli,3F8PK@33958|Lactobacillaceae 91061|Bacilli S D-Ala-teichoic acid biosynthesis protein dltX - - - - - - - - - - - DUF3687 MHFCBNDO_00870 543734.LCABL_08550 0.0 1011.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,3F49R@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - AMP-binding,AMP-binding_C MHFCBNDO_00871 543734.LCABL_08560 9.86e-304 827.0 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,3F4KK@33958|Lactobacillaceae 91061|Bacilli M MBOAT, membrane-bound O-acyltransferase family dltB - - ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - MBOAT MHFCBNDO_00872 543734.LCABL_08570 6.97e-49 155.0 COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli,3F7Q1@33958|Lactobacillaceae 91061|Bacilli J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding MHFCBNDO_00873 543734.LCABL_08580 2.89e-312 850.0 COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli,3F3WE@33958|Lactobacillaceae 91061|Bacilli M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) dltD - - ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - DltD MHFCBNDO_00874 543734.LCABL_08590 6.77e-111 319.0 COG1719@1|root,COG1719@2|Bacteria,1VD7N@1239|Firmicutes,4HKV3@91061|Bacilli,3F7ZI@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2507) yslB - - - - - - - - - - - DUF2507 MHFCBNDO_00875 543734.LCABL_08600 0.0 951.0 COG0127@1|root,COG0796@1|root,COG0127@2|Bacteria,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli,3F446@33958|Lactobacillaceae 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race MHFCBNDO_00876 543734.LCABL_08610 4.7e-125 355.0 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli,3F73R@33958|Lactobacillaceae 91061|Bacilli S Phosphoesterase ysnB GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K07095 - - - - ko00000 - - - Metallophos_2 MHFCBNDO_00877 543734.LCABL_08620 5.44e-175 488.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HE39@91061|Bacilli,3FCCB@33958|Lactobacillaceae 91061|Bacilli U Major intrinsic protein gla - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP MHFCBNDO_00878 543734.LCABL_08630 9.32e-112 321.0 COG0517@1|root,COG0517@2|Bacteria,1VFAB@1239|Firmicutes,4HRWJ@91061|Bacilli,3FBMW@33958|Lactobacillaceae 91061|Bacilli S CBS domain ykuL - - - - - - - - - - - CBS MHFCBNDO_00879 543734.LCABL_08640 4.63e-199 553.0 COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,4HBE3@91061|Bacilli,3F4QH@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF368) - - - ko:K08974 - - - - ko00000 - - - DUF368 MHFCBNDO_00880 543734.LCABL_08650 6.86e-198 550.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,3F49U@33958|Lactobacillaceae 91061|Bacilli M mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel MHFCBNDO_00881 543734.LCABL_08660 1.49e-46 154.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,3F6KB@33958|Lactobacillaceae 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 MHFCBNDO_00882 543734.LCABL_08670 4.84e-114 328.0 COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,3F8GC@33958|Lactobacillaceae 91061|Bacilli S YtxH-like protein ytxH - - - - - - - - - - - YtxH MHFCBNDO_00883 543734.LCABL_08680 7.49e-117 335.0 COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli,3F7V1@33958|Lactobacillaceae 91061|Bacilli S 3H domain yrxA - - ko:K07105 - - - - ko00000 - - - 3H,HTH_11 MHFCBNDO_00884 543734.LCABL_08690 1.8e-273 747.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,3F3X5@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 MHFCBNDO_00885 543734.LCABL_08700 3.03e-232 640.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,3F4AA@33958|Lactobacillaceae 91061|Bacilli K catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 MHFCBNDO_00886 1423732.BALS01000001_gene1381 0.0 1477.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F4ZE@33958|Lactobacillaceae 91061|Bacilli M Penicillin binding protein transpeptidase domain pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase MHFCBNDO_00887 543734.LCABL_08750 8.72e-163 455.0 COG1011@1|root,COG1011@2|Bacteria,1TRQ6@1239|Firmicutes,4HKAS@91061|Bacilli,3FBG9@33958|Lactobacillaceae 91061|Bacilli S HAD-hyrolase-like yfnB - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 MHFCBNDO_00888 543734.LCABL_08760 5.87e-177 493.0 COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,3F5HY@33958|Lactobacillaceae 91061|Bacilli H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 MHFCBNDO_00889 543734.LCABL_08770 0.0 935.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,3F3UV@33958|Lactobacillaceae 91061|Bacilli E dipeptidase PepV pepV - 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 MHFCBNDO_00890 543734.LCABL_08780 0.0 889.0 COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,3FC1S@33958|Lactobacillaceae 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD MHFCBNDO_00891 543734.LCABL_08790 9.98e-73 218.0 2C26E@1|root,3424N@2|Bacteria,1VX4A@1239|Firmicutes,4HXT9@91061|Bacilli,3F70Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00892 543734.LCABL_08810 8.95e-132 381.0 COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,4HCP3@91061|Bacilli,3F3M9@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibE - - - - - - - - - - - YibE_F MHFCBNDO_00893 543734.LCABL_08810 7.67e-93 280.0 COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,4HCP3@91061|Bacilli,3F3M9@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibE - - - - - - - - - - - YibE_F MHFCBNDO_00894 543734.LCABL_08820 3.27e-151 427.0 COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,4HBKX@91061|Bacilli,3F3S6@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibF - - - - - - - - - - - YibE_F MHFCBNDO_00895 543734.LCABL_08830 7.41e-148 416.0 COG4186@1|root,COG4186@2|Bacteria,1V40Y@1239|Firmicutes,4HH4J@91061|Bacilli,3F4EX@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos,Metallophos_2 MHFCBNDO_00896 543734.LCABL_08840 0.0 920.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,3F4ZD@33958|Lactobacillaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos MHFCBNDO_00897 543734.LCABL_08850 2.93e-150 422.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli,3F66P@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1027) yutD - - - - - - - - - - - DUF1027 MHFCBNDO_00898 543734.LCABL_08860 1.34e-186 518.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,3F49D@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like MHFCBNDO_00899 543734.LCABL_08870 2.62e-145 409.0 COG4478@1|root,COG4478@2|Bacteria,1V7UW@1239|Firmicutes,4HHH4@91061|Bacilli,3F4YP@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1461) - - - - - - - - - - - - DUF1461 MHFCBNDO_00900 543734.LCABL_08880 8.69e-149 419.0 COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,4HG3F@91061|Bacilli,3F4KG@33958|Lactobacillaceae 91061|Bacilli S SNARE-like domain protein dedA - - ko:K03975 - - - - ko00000 - - - SNARE_assoc MHFCBNDO_00901 543734.LCABL_08890 2.26e-115 330.0 COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,3F6QT@33958|Lactobacillaceae 91061|Bacilli I Phosphatidylglycerophosphatase A pgpA - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA MHFCBNDO_00902 543734.LCABL_08900 1.35e-237 653.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,3F3NQ@33958|Lactobacillaceae 91061|Bacilli C Ferredoxin--NADP reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 MHFCBNDO_00903 543734.LCABL_08910 2.99e-140 395.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,3F3TI@33958|Lactobacillaceae 91061|Bacilli G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Hydrolase_3,Pro_isomerase MHFCBNDO_00904 543734.LCABL_08920 1.17e-82 244.0 COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli,3F6AN@33958|Lactobacillaceae 91061|Bacilli J general stress protein yugI - - ko:K07570 - - - - ko00000 - - - S1 MHFCBNDO_00905 568703.LGG_00307 5.19e-90 263.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - MHFCBNDO_00933 543734.LCABL_09250 2.38e-122 349.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation sigH - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 MHFCBNDO_00934 543734.LCABL_09260 0.0 1009.0 COG0531@1|root,COG0531@2|Bacteria,1TPJH@1239|Firmicutes,4HC13@91061|Bacilli,3F4AR@33958|Lactobacillaceae 91061|Bacilli E amino acid ybeC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 MHFCBNDO_00935 543734.LCABL_09270 1.09e-294 803.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli,3F4H5@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein pimB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 MHFCBNDO_00936 543734.LCABL_09280 1.13e-252 692.0 COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HB9F@91061|Bacilli,3F47X@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 2.4.1.208 ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 - R05164,R10865 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 MHFCBNDO_00937 543734.LCABL_09290 1.58e-220 610.0 COG0392@1|root,COG0392@2|Bacteria,1UY7Z@1239|Firmicutes,4HCG6@91061|Bacilli,3F3UR@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM MHFCBNDO_00939 543734.LCABL_09310 1.56e-277 759.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase araT - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 MHFCBNDO_00940 543734.LCABL_09320 1.52e-57 178.0 COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli,3F82V@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1797) ykuJ - - - - - - - - - - - DUF1797 MHFCBNDO_00941 543734.LCABL_09330 0.0 1366.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase MHFCBNDO_00942 543734.LCABL_09340 8.92e-105 302.0 COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli,3F67J@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Fur family perR - - ko:K03711,ko:K09825 - - - - ko00000,ko03000 - - - FUR MHFCBNDO_00943 568703.LGG_00307 5.19e-90 263.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - MHFCBNDO_00949 1423816.BACQ01000026_gene919 1.98e-91 274.0 29Q2N@1|root,30B1A@2|Bacteria,1U7D8@1239|Firmicutes,4IH94@91061|Bacilli,3F9EU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00950 543734.LCABL_09430 4.56e-267 733.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,3F3T0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N MHFCBNDO_00951 543734.LCABL_09440 0.0 934.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator mdr - - - - - - - - - - - MFS_1 MHFCBNDO_00952 543734.LCABL_09450 3.99e-106 306.0 COG0789@1|root,COG0789@2|Bacteria,1UD22@1239|Firmicutes,4IFKE@91061|Bacilli,3F8M4@33958|Lactobacillaceae 91061|Bacilli K MerR HTH family regulatory protein - - - - - - - - - - - - MerR_1 MHFCBNDO_00953 543734.LCABL_09460 0.0 914.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 MHFCBNDO_00954 543734.LCABL_09470 3.74e-155 437.0 2C9UQ@1|root,32RPZ@2|Bacteria,1VDDQ@1239|Firmicutes,4HNJB@91061|Bacilli,3F5X9@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4811) - - - - - - - - - - - - DUF4811 MHFCBNDO_00955 543734.LCABL_09480 3.66e-155 436.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,3F5CM@33958|Lactobacillaceae 91061|Bacilli I Acid phosphatase homologues yodM - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 MHFCBNDO_00956 543734.LCABL_09490 0.0 1676.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,3F46M@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 MHFCBNDO_00957 543734.LCABL_09500 0.0 1012.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,3F404@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C MHFCBNDO_00958 543734.LCABL_09510 4.65e-167 467.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,3F41G@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 MHFCBNDO_00959 568703.LGG_00853 9.15e-45 144.0 COG3478@1|root,COG3478@2|Bacteria,1VEIV@1239|Firmicutes,4HPKA@91061|Bacilli,3FAC9@33958|Lactobacillaceae 91061|Bacilli S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) yhcC - - ko:K07069 - - - - ko00000 - - - zinc_ribbon_13 MHFCBNDO_00960 543734.LCABL_09520 3.37e-183 511.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,3F480@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N MHFCBNDO_00961 543734.LCABL_09530 2.55e-121 345.0 COG1051@1|root,COG1051@2|Bacteria,1VDM3@1239|Firmicutes,4HMI0@91061|Bacilli,3F6RN@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX MHFCBNDO_00963 543734.LCABL_09550 4.81e-275 752.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HA65@91061|Bacilli,3F3NJ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family int3 - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase MHFCBNDO_00964 543734.LCABL_09560 1.64e-263 721.0 COG4823@1|root,COG4823@2|Bacteria,1V38S@1239|Firmicutes,4HJAT@91061|Bacilli,3F943@33958|Lactobacillaceae 91061|Bacilli V Abi-like protein - - - - - - - - - - - - Abi_2 MHFCBNDO_00965 543734.LCABL_09570 1.68e-94 276.0 2DT24@1|root,33IBQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - MHFCBNDO_00966 1423734.JCM14202_421 4.14e-15 75.9 29P54@1|root,30A3B@2|Bacteria,1U64T@1239|Firmicutes,4IFUC@91061|Bacilli,3F71V@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00967 568703.LGG_02700 1.09e-23 93.6 2BTCZ@1|root,32NIR@2|Bacteria,1U8DY@1239|Firmicutes,4IIBW@91061|Bacilli,3FAVQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00968 1423732.BALS01000053_gene2770 1.38e-110 325.0 COG2126@1|root,COG2126@2|Bacteria,1UJ2F@1239|Firmicutes,4ISZM@91061|Bacilli,3FBU0@33958|Lactobacillaceae 91061|Bacilli J Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2 MHFCBNDO_00970 1423734.JCM14202_3082 1.03e-21 89.4 COG1396@1|root,COG1396@2|Bacteria,1VEP9@1239|Firmicutes,4HPCR@91061|Bacilli,3F871@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_26,HTH_3 MHFCBNDO_00972 543734.LCABL_09620 1.67e-162 456.0 COG1737@1|root,COG3646@1|root,COG1737@2|Bacteria,COG3646@2|Bacteria,1V777@1239|Firmicutes,4ITNA@91061|Bacilli,3F4KB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - Phage_pRha MHFCBNDO_00974 543734.LCABL_09630 3.74e-52 163.0 COG4707@1|root,COG4707@2|Bacteria,1TVWF@1239|Firmicutes,4I4HD@91061|Bacilli,3F8XD@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF771) - - - - - - - - - - - - DUF771 MHFCBNDO_00977 1423816.BACQ01000064_gene2523 5.65e-140 399.0 COG3935@1|root,COG3935@2|Bacteria,1VHK1@1239|Firmicutes,4HQY7@91061|Bacilli,3FCF5@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain - - - - - - - - - - - - DnaB_2,HTH_36 MHFCBNDO_00978 543734.LCABL_05660 4.88e-197 546.0 COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,4HH4U@91061|Bacilli,3F6BK@33958|Lactobacillaceae 91061|Bacilli L IstB-like ATP binding protein pi346 - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 MHFCBNDO_00981 1367847.JCM7686_0815 2.67e-24 96.7 COG0500@1|root,COG2226@2|Bacteria,1QUBD@1224|Proteobacteria 1224|Proteobacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11 MHFCBNDO_00982 1423816.BACQ01000027_gene953 1.01e-23 93.6 COG0500@1|root,COG2226@2|Bacteria,1V56J@1239|Firmicutes,4HK75@91061|Bacilli,3F6XF@33958|Lactobacillaceae 91061|Bacilli Q DNA (cytosine-5-)-methyltransferase activity - - - - - - - - - - - - Methyltransf_11 MHFCBNDO_00985 543734.LCABL_05720 3.15e-66 204.0 2DCNS@1|root,2ZESF@2|Bacteria,1W51N@1239|Firmicutes,4I1NU@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00986 675815.VOA_000555 1.9e-82 261.0 COG0454@1|root,COG0456@2|Bacteria,1NFJW@1224|Proteobacteria,1RY4C@1236|Gammaproteobacteria,1XWH7@135623|Vibrionales 135623|Vibrionales K acetyltransferase - - - - - - - - - - - - - MHFCBNDO_00987 198628.Dda3937_01763 3.54e-39 134.0 COG4933@1|root,COG4933@2|Bacteria,1N2JZ@1224|Proteobacteria,1S9JD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ASCH - - - - - - - - - - - - ASCH MHFCBNDO_00988 543734.LCABL_05760 3.4e-11 62.0 2C1BV@1|root,33HNE@2|Bacteria,1VQQP@1239|Firmicutes,4HWNS@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - GcrA MHFCBNDO_00989 543734.LCABL_09800 4.17e-89 261.0 COG1403@1|root,COG1403@2|Bacteria,1VEKN@1239|Firmicutes,4HNP8@91061|Bacilli 91061|Bacilli V HNH endonuclease - - - - - - - - - - - - HNH MHFCBNDO_00990 543734.LCABL_09810 2.38e-79 236.0 2C080@1|root,3338D@2|Bacteria,1VH6C@1239|Firmicutes,4HRRT@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00991 543734.LCABL_09820 0.0 1176.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,3F51U@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name - - - - - - - - - - - - Terminase_1 MHFCBNDO_00992 543734.LCABL_09830 8.05e-297 810.0 COG4695@1|root,COG4695@2|Bacteria,1TVVS@1239|Firmicutes,4HGGK@91061|Bacilli 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal MHFCBNDO_00993 543734.LCABL_09840 2.39e-164 460.0 COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,4HBZH@91061|Bacilli,3F5E9@33958|Lactobacillaceae 91061|Bacilli OU Belongs to the peptidase S14 family clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease MHFCBNDO_00994 543734.LCABL_11110 7.56e-285 779.0 COG4653@1|root,COG4653@2|Bacteria,1TT8C@1239|Firmicutes,4HFEY@91061|Bacilli 91061|Bacilli S Phage capsid family - - - - - - - - - - - - Phage_capsid MHFCBNDO_00996 543734.LCABL_09870 9.08e-71 213.0 29QJ9@1|root,30BIU@2|Bacteria,1U86W@1239|Firmicutes,4II4I@91061|Bacilli,3FAMD@33958|Lactobacillaceae 543734.LCABL_09870|- - - - - - - - - - - - - - - - MHFCBNDO_00997 543734.LCABL_09880 3.92e-76 227.0 2CBTS@1|root,347GG@2|Bacteria,1VZW7@1239|Firmicutes,4HZBB@91061|Bacilli 91061|Bacilli S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join MHFCBNDO_00998 543734.LCABL_09890 1.28e-75 225.0 28SFR@1|root,2ZES9@2|Bacteria,1W5S0@1239|Firmicutes,4HZGB@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_00999 543734.LCABL_09900 1.24e-86 254.0 29N3D@1|root,30914@2|Bacteria,1U49Q@1239|Firmicutes,4HZJW@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - HK97-gp10_like MHFCBNDO_01000 543734.LCABL_09910 1.24e-147 416.0 2FEHG@1|root,346H0@2|Bacteria,1VYX6@1239|Firmicutes,4HYYE@91061|Bacilli,3FA6D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01001 543734.LCABL_11180 5.81e-80 237.0 2DG6G@1|root,2ZUQK@2|Bacteria,1W5EM@1239|Firmicutes,4I057@91061|Bacilli,3FA5T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01002 543734.LCABL_11200 0.0 1251.0 COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli,3F5K4@33958|Lactobacillaceae 91061|Bacilli D Phage tail tape measure protein - - - - - - - - - - - - Peptidase_M23,PhageMin_Tail,SLT MHFCBNDO_01003 543734.LCABL_09950 1.69e-162 455.0 COG4722@1|root,COG4722@2|Bacteria,1V6VK@1239|Firmicutes,4IQ68@91061|Bacilli,3FBGA@33958|Lactobacillaceae 1239|Firmicutes S phage tail - - - - - - - - - - - - - MHFCBNDO_01004 543734.LCABL_11220 0.0 2348.0 COG0497@1|root,COG0845@1|root,COG4926@1|root,COG0497@2|Bacteria,COG0845@2|Bacteria,COG4926@2|Bacteria,1V2Q6@1239|Firmicutes,4HNI9@91061|Bacilli,3FBTW@33958|Lactobacillaceae 91061|Bacilli LM gp58-like protein - - - - - - - - - - - - Gp58,Prophage_tail MHFCBNDO_01005 543734.LCABL_09970 1.69e-93 273.0 2CK55@1|root,33IEZ@2|Bacteria,1VKGF@1239|Firmicutes,4HS4Y@91061|Bacilli,3F96E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF1617 MHFCBNDO_01006 543734.LCABL_09980 2.49e-48 155.0 2DR4E@1|root,33A44@2|Bacteria,1VMJT@1239|Firmicutes,4HR27@91061|Bacilli,3F8PF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01007 543734.LCABL_09990 3.36e-61 188.0 2C26M@1|root,30A6X@2|Bacteria,1U69U@1239|Firmicutes,4IG11@91061|Bacilli,3F7E8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01008 543734.LCABL_10000 7.01e-67 206.0 COG5546@1|root,COG5546@2|Bacteria,1VGGV@1239|Firmicutes,4HPNN@91061|Bacilli,3F9QK@33958|Lactobacillaceae 91061|Bacilli S Bacteriophage holin hol - - - - - - - - - - - Phage_holin_1 MHFCBNDO_01010 543734.LCABL_10020 3.78e-251 687.0 COG0791@1|root,COG0791@2|Bacteria,1VT9V@1239|Firmicutes,4HV77@91061|Bacilli 91061|Bacilli M Bacteriophage peptidoglycan hydrolase - - - - - - - - - - - - Amidase_5 MHFCBNDO_01011 543734.LCABL_10040 0.0 989.0 COG0438@1|root,COG0438@2|Bacteria,1V1TS@1239|Firmicutes,4HG8T@91061|Bacilli,3FC16@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 tagE2 - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Asp1,Glycos_transf_1 MHFCBNDO_01012 543734.LCABL_10050 0.0 1050.0 COG0438@1|root,COG0438@2|Bacteria,1UZU7@1239|Firmicutes,4H9N9@91061|Bacilli,3FC17@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 tagE3 - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Glycos_transf_1 MHFCBNDO_01013 543734.LCABL_10060 9.78e-112 320.0 COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli,3F6A9@33958|Lactobacillaceae 91061|Bacilli O Belongs to the glutathione peroxidase family gpo - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx MHFCBNDO_01016 543734.LCABL_10070 2.22e-298 813.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 MHFCBNDO_01017 543734.LCABL_10090 0.0 895.0 COG1409@1|root,COG1409@2|Bacteria,1UQCQ@1239|Firmicutes,4HG8Z@91061|Bacilli,3F483@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase cpdA - - - - - - - - - - - Metallophos MHFCBNDO_01018 543734.LCABL_10100 5.05e-52 164.0 COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,4HNJ4@91061|Bacilli,3F811@33958|Lactobacillaceae 91061|Bacilli T Belongs to the UPF0237 family XK27_08630 - - ko:K07166 - - - - ko00000 - - - ACT_6 MHFCBNDO_01019 543734.LCABL_10110 5.58e-312 852.0 COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,4HBTU@91061|Bacilli,3F4H2@33958|Lactobacillaceae 91061|Bacilli S UPF0210 protein XK27_08635 - - ko:K09157 - - - - ko00000 - - - DUF711 MHFCBNDO_01020 543734.LCABL_10120 4.22e-273 744.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA MHFCBNDO_01021 543734.LCABL_10130 6.41e-148 416.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,3F6QR@33958|Lactobacillaceae 91061|Bacilli Q Thioredoxin yjbH - - - - - - - - - - - Thioredoxin_5 MHFCBNDO_01022 543734.LCABL_10140 7.28e-138 390.0 COG4116@1|root,COG4116@2|Bacteria,1TTVM@1239|Firmicutes,4I4A3@91061|Bacilli,3F4YS@33958|Lactobacillaceae 91061|Bacilli S CYTH - - - - - - - - - - - - CYTH MHFCBNDO_01023 543734.LCABL_10150 1.19e-158 444.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,3F452@33958|Lactobacillaceae 91061|Bacilli S RelA SpoT domain protein yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT MHFCBNDO_01024 543734.LCABL_10160 1.05e-193 537.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,3F45D@33958|Lactobacillaceae 91061|Bacilli F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase MHFCBNDO_01025 543734.LCABL_10170 5.81e-218 601.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3F4AU@33958|Lactobacillaceae 91061|Bacilli G Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 MHFCBNDO_01026 543734.LCABL_10180 9.8e-259 708.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HA6Y@91061|Bacilli,3FB4B@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE MHFCBNDO_01027 543734.LCABL_10190 2.24e-148 417.0 COG3142@1|root,COG3142@2|Bacteria,1TQYI@1239|Firmicutes,4HE1E@91061|Bacilli,3F4NZ@33958|Lactobacillaceae 91061|Bacilli P Participates in the control of copper homeostasis cutC - - ko:K06201 - - - - ko00000 - - - CutC MHFCBNDO_01028 543734.LCABL_10200 1.09e-183 512.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli,3F510@33958|Lactobacillaceae 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA MHFCBNDO_01029 543734.LCABL_10210 9.35e-254 695.0 COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,3F3RC@33958|Lactobacillaceae 91061|Bacilli G Lactonase, 7-bladed beta-propeller pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase MHFCBNDO_01030 543734.LCABL_10220 1.16e-81 242.0 COG3731@1|root,COG3731@2|Bacteria,1VGKB@1239|Firmicutes,4HNJN@91061|Bacilli,3F8EZ@33958|Lactobacillaceae 91061|Bacilli G PTS system glucitol/sorbitol-specific IIA component srlB - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA MHFCBNDO_01031 1423732.BALS01000004_gene1205 4.12e-56 174.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HKK1@91061|Bacilli,3F7KX@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 MHFCBNDO_01032 543734.LCABL_10240 4.94e-245 672.0 COG0516@1|root,COG0516@2|Bacteria,1TNYF@1239|Firmicutes,4HA55@91061|Bacilli,3F45K@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaC - 1.7.1.7 ko:K00364 ko00230,map00230 - R01134 RC00457 ko00000,ko00001,ko01000 - - iSB619.SA_RS06660 IMPDH MHFCBNDO_01033 543734.LCABL_10250 1.94e-219 606.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,3F4B8@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA MHFCBNDO_01034 543734.LCABL_10260 3.44e-200 554.0 COG0500@1|root,COG2226@2|Bacteria,1V1WE@1239|Firmicutes,4HGQ9@91061|Bacilli,3F4U3@33958|Lactobacillaceae 91061|Bacilli H Methyltransferase rrmA - 2.1.1.187 ko:K00563,ko:K10947 - - R07233 RC00003 ko00000,ko01000,ko03000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 MHFCBNDO_01035 543734.LCABL_10270 1.86e-124 353.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,3F42Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase MHFCBNDO_01036 543734.LCABL_10280 4.04e-94 274.0 COG4835@1|root,COG4835@2|Bacteria,1VJ7H@1239|Firmicutes,4HP0P@91061|Bacilli,3F6JB@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1149) - - - - - - - - - - - - DUF1149 MHFCBNDO_01037 543734.LCABL_10290 0.0 1425.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,3F3JZ@33958|Lactobacillaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma MHFCBNDO_01038 543734.LCABL_10300 1.9e-295 807.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,3F3SA@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 inactive domain protein ymfF - - - - - - - - - - - Peptidase_M16_C MHFCBNDO_01039 543734.LCABL_10310 1.13e-308 841.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,3F4MU@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C MHFCBNDO_01040 543734.LCABL_10320 3.01e-166 465.0 COG1028@1|root,COG1028@2|Bacteria,1V0YW@1239|Firmicutes,4ISGK@91061|Bacilli,3FBEA@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 MHFCBNDO_01041 543734.LCABL_10330 1.15e-169 479.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,3F3SM@33958|Lactobacillaceae 91061|Bacilli S Helix-turn-helix domain ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 MHFCBNDO_01042 543734.LCABL_10340 9.93e-136 384.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,3F4BI@33958|Lactobacillaceae 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf MHFCBNDO_01044 543734.LCABL_10350 4.1e-291 795.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,3F4I4@33958|Lactobacillaceae 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth MHFCBNDO_01045 543734.LCABL_10360 3.74e-243 669.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA MHFCBNDO_01046 543734.LCABL_10370 7.95e-317 870.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,3F3WX@33958|Lactobacillaceae 91061|Bacilli S Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 MHFCBNDO_01047 543734.LCABL_10380 1.14e-148 419.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli,3F3SQ@33958|Lactobacillaceae 91061|Bacilli S YigZ family yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 MHFCBNDO_01048 543734.LCABL_10390 6.41e-299 816.0 COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli,3F3TQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K02240 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1 - - DEAD,Helicase_C,ResIII MHFCBNDO_01049 568703.LGG_00895 6.13e-104 306.0 COG1040@1|root,COG1040@2|Bacteria,1V73S@1239|Firmicutes,4HJ6R@91061|Bacilli,3F714@33958|Lactobacillaceae 91061|Bacilli S Competence protein comFC - - ko:K02242 - M00429 - - ko00000,ko00002,ko02044 - - - Pribosyltran MHFCBNDO_01050 543734.LCABL_10410 3.24e-126 359.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,3F40M@33958|Lactobacillaceae 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE MHFCBNDO_01051 543734.LCABL_10420 0.0 1535.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,3F4DH@33958|Lactobacillaceae 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SecA_DEAD,SecA_PP_bind,SecA_SW MHFCBNDO_01052 1423732.BALS01000004_gene1228 8.69e-239 658.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,3F3SN@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 MHFCBNDO_01053 543734.LCABL_10450 1.28e-160 450.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,3F4JC@33958|Lactobacillaceae 91061|Bacilli D ABC transporter ftsE GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran MHFCBNDO_01054 543734.LCABL_10460 1.34e-200 556.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,3F4MK@33958|Lactobacillaceae 91061|Bacilli D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX MHFCBNDO_01055 543734.LCABL_10470 3.16e-258 708.0 COG0265@1|root,COG0265@2|Bacteria,1TSBA@1239|Firmicutes,4HA05@91061|Bacilli,3F4TP@33958|Lactobacillaceae 91061|Bacilli O Domain present in PSD-95, Dlg, and ZO-1/2. minJ - - - - - - - - - - - PDZ_2 MHFCBNDO_01056 543734.LCABL_10480 1.83e-168 470.0 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,3FC91@33958|Lactobacillaceae 91061|Bacilli K response regulator phoP - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C MHFCBNDO_01057 543734.LCABL_10490 0.0 1062.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,3F3W2@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like MHFCBNDO_01058 543734.LCABL_10500 1.76e-196 545.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 MHFCBNDO_01059 543734.LCABL_10510 4.48e-205 569.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,3F3NI@33958|Lactobacillaceae 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 MHFCBNDO_01060 543734.LCABL_10520 1.06e-201 559.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,3F412@33958|Lactobacillaceae 91061|Bacilli P Phosphate transport system permease protein PstA pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 MHFCBNDO_01061 543734.LCABL_10530 9.06e-192 532.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB2 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran MHFCBNDO_01062 543734.LCABL_10540 3.54e-180 501.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB1 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran MHFCBNDO_01063 543734.LCABL_10550 3.82e-156 438.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,3F46W@33958|Lactobacillaceae 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU MHFCBNDO_01064 543734.LCABL_10560 0.0 940.0 COG2433@1|root,COG3595@1|root,COG2433@2|Bacteria,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,3F5QQ@33958|Lactobacillaceae 91061|Bacilli S Putative adhesin yvlB - - - - - - - - - - - DUF4097 MHFCBNDO_01065 543734.LCABL_10570 5.23e-50 159.0 2A2TA@1|root,30R6T@2|Bacteria,1U7RM@1239|Firmicutes,4IHNY@91061|Bacilli,3FA2M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01066 543734.LCABL_10580 3.07e-50 161.0 COG1950@1|root,COG1950@2|Bacteria,1VF4I@1239|Firmicutes,4HNXP@91061|Bacilli,3F7IN@33958|Lactobacillaceae 91061|Bacilli S Mycobacterial 4 TMS phage holin, superfamily IV yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 MHFCBNDO_01067 543734.LCABL_10590 8.27e-223 615.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,3F3Z3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N MHFCBNDO_01068 543734.LCABL_10600 7.94e-202 558.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,3F42N@33958|Lactobacillaceae 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT MHFCBNDO_01069 543734.LCABL_10610 1.48e-248 682.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,3F4C8@33958|Lactobacillaceae 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N MHFCBNDO_01070 543734.LCABL_10620 1.43e-226 624.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,3F411@33958|Lactobacillaceae 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 MHFCBNDO_01071 543734.LCABL_10630 0.0 1130.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,3F457@33958|Lactobacillaceae 91061|Bacilli G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV MHFCBNDO_01072 543734.LCABL_10640 1.51e-148 418.0 COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,4HDD2@91061|Bacilli,3F6EC@33958|Lactobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C MHFCBNDO_01073 543734.LCABL_10650 9.33e-222 613.0 COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,4HAPG@91061|Bacilli,3F619@33958|Lactobacillaceae 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA MHFCBNDO_01074 1231336.L248_2708 1.47e-118 343.0 COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4HGIE@91061|Bacilli,3F6NW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_01075 543734.LCABL_10680 0.0 1453.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TRAS@1239|Firmicutes,4HC7R@91061|Bacilli,3F5WX@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD MHFCBNDO_01076 543734.LCABL_10690 1.99e-153 431.0 COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,4HA8H@91061|Bacilli,3F4RZ@33958|Lactobacillaceae 91061|Bacilli S HD containing hydrolase-like enzyme yfbR - - ko:K07023 - - - - ko00000 - - - HD_2 MHFCBNDO_01077 543734.LCABL_10700 0.0 1302.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,3F3XM@33958|Lactobacillaceae 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB MHFCBNDO_01078 543734.LCABL_10710 0.0 1900.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,3F4TZ@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran MHFCBNDO_01079 543734.LCABL_10720 3.63e-111 321.0 COG3247@1|root,COG3247@2|Bacteria,1VJ0U@1239|Firmicutes,4HQJ0@91061|Bacilli,3FB5N@33958|Lactobacillaceae 91061|Bacilli S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 MHFCBNDO_01080 543734.LCABL_10730 8.53e-213 587.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,3F4NY@33958|Lactobacillaceae 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 MHFCBNDO_01081 543734.LCABL_10740 2.99e-248 681.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,3F4D5@33958|Lactobacillaceae 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 MHFCBNDO_01082 543734.LCABL_10750 9.63e-220 607.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,3F4AB@33958|Lactobacillaceae 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N MHFCBNDO_01083 543734.LCABL_10760 3.19e-105 303.0 COG1846@1|root,COG1846@2|Bacteria,1V6G0@1239|Firmicutes,4HKQR@91061|Bacilli,3F74F@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein ohrR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K18906 - M00700,M00702,M00704,M00717 - - ko00000,ko00002,ko01504,ko03000 - - - MarR MHFCBNDO_01084 543734.LCABL_10770 5.97e-132 375.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,3F3M0@33958|Lactobacillaceae 91061|Bacilli O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease MHFCBNDO_01087 543734.LCABL_11290 5.52e-241 663.0 COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,3F53Y@33958|Lactobacillaceae 91061|Bacilli K Putative sugar-binding domain cggR - - ko:K05311 - - - - ko00000,ko03000 - - - Sugar-bind MHFCBNDO_01088 543734.LCABL_11300 2.1e-247 679.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,3F3JS@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N MHFCBNDO_01089 543734.LCABL_11310 2.16e-282 772.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,3F3SC@33958|Lactobacillaceae 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK MHFCBNDO_01090 543734.LCABL_11320 2.81e-180 501.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,3F494@33958|Lactobacillaceae 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM MHFCBNDO_01091 543734.LCABL_11330 2.05e-313 853.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,3F3JP@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N MHFCBNDO_01092 543734.LCABL_11340 5.21e-293 801.0 COG0477@1|root,COG2814@2|Bacteria,1TRZB@1239|Firmicutes,4HBXV@91061|Bacilli,3F5A0@33958|Lactobacillaceae 91061|Bacilli EGP Transmembrane secretion effector mdt(A) - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1,MFS_2,MFS_3 MHFCBNDO_01093 543734.LCABL_11350 8.99e-62 190.0 29QBC@1|root,30BAJ@2|Bacteria,1U7TN@1239|Firmicutes,4IHR4@91061|Bacilli,3FA5U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01094 543734.LCABL_11360 0.0 1007.0 COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F3MU@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC MHFCBNDO_01095 543734.LCABL_11370 5.04e-43 140.0 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli,3F7IQ@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG MHFCBNDO_01096 543734.LCABL_11380 4.01e-181 503.0 COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4HBE6@91061|Bacilli,3F5XW@33958|Lactobacillaceae 91061|Bacilli S Serine aminopeptidase, S33 est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 MHFCBNDO_01097 543734.LCABL_11390 0.0 1573.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,3F4EC@33958|Lactobacillaceae 91061|Bacilli J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 MHFCBNDO_01098 543734.LCABL_11400 4.47e-108 311.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,3F65B@33958|Lactobacillaceae 91061|Bacilli J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB MHFCBNDO_01099 543734.LCABL_11410 2.21e-226 624.0 COG1609@1|root,COG1609@2|Bacteria,1U6Z4@1239|Firmicutes,4HC2A@91061|Bacilli,3F3ZC@33958|Lactobacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor yvdE - - - - - - - - - - - LacI,Peripla_BP_3 MHFCBNDO_01100 543734.LCABL_11420 0.0 1118.0 COG0366@1|root,COG0366@2|Bacteria,1UY2T@1239|Firmicutes,4HBRE@91061|Bacilli,3FC10@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain malA1 - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,Malt_amylase_C MHFCBNDO_01101 543734.LCABL_11430 0.0 1211.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,3F41N@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family nplT - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Alpha-amylase_N,Malt_amylase_C MHFCBNDO_01102 543734.LCABL_11440 0.0 1512.0 COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,3F3PG@33958|Lactobacillaceae 91061|Bacilli G hydrolase, family 65, central catalytic mapA - 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 - R01555 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m MHFCBNDO_01103 543734.LCABL_11450 6.75e-153 431.0 COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,4HHB1@91061|Bacilli,3FCA1@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 5.4.2.6 ko:K01838 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 MHFCBNDO_01104 543734.LCABL_11460 3.7e-21 90.5 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,3FC3D@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 MHFCBNDO_01105 543734.LCABL_11460 3.01e-16 78.2 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,3FC3D@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 MHFCBNDO_01106 1423732.BALS01000019_gene1832 2.33e-23 92.8 29QAR@1|root,30B9X@2|Bacteria,1U7SN@1239|Firmicutes,4IHQ2@91061|Bacilli,3FA4A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01107 543734.LCABL_11520 1.13e-32 113.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli,3F85E@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 MHFCBNDO_01108 543734.LCABL_11530 1.03e-305 832.0 COG0595@1|root,COG0595@2|Bacteria,1V0AV@1239|Firmicutes,4HEB0@91061|Bacilli,3FB9R@33958|Lactobacillaceae 91061|Bacilli S Metallo-beta-lactamase superfamily YSH1 - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,Lactamase_B_2 MHFCBNDO_01109 543734.LCABL_11540 8.67e-312 850.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HEKH@91061|Bacilli,3F4P5@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 MHFCBNDO_01110 543734.LCABL_11550 1.1e-188 525.0 COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,4HBKE@91061|Bacilli,3FC8I@33958|Lactobacillaceae 91061|Bacilli G Binding-protein-dependent transport system inner membrane component malF - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 MHFCBNDO_01111 543734.LCABL_11560 7.01e-213 588.0 COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,4HCD0@91061|Bacilli,3F464@33958|Lactobacillaceae 91061|Bacilli P ABC-type sugar transport systems, permease components - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 MHFCBNDO_01112 543734.LCABL_11570 3.08e-248 682.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HBKK@91061|Bacilli,3FC3J@33958|Lactobacillaceae 91061|Bacilli P ATPases associated with a variety of cellular activities malK - - ko:K10112,ko:K17240 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00599,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.38 - - ABC_tran,TOBE_2 MHFCBNDO_01113 543734.LCABL_11580 3.63e-136 385.0 COG0454@1|root,COG0456@2|Bacteria,1V7GR@1239|Firmicutes,4HJ11@91061|Bacilli,3FB97@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - ko:K06977 - - - - ko00000 - - - Acetyltransf_1 MHFCBNDO_01114 543734.LCABL_11590 7.57e-119 339.0 COG4894@1|root,COG4894@2|Bacteria,1V8EY@1239|Firmicutes,4HMMS@91061|Bacilli,3F698@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - LOR MHFCBNDO_01115 543734.LCABL_11600 4e-203 563.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,3F58Y@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase ycsE - - - - - - - - - - - Hydrolase_3 MHFCBNDO_01116 543734.LCABL_11610 5.91e-166 463.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,3F3W0@33958|Lactobacillaceae 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG MHFCBNDO_01117 543734.LCABL_11620 8.65e-228 628.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,3F3MW@33958|Lactobacillaceae 91061|Bacilli C phosphate acetyltransferase pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB MHFCBNDO_01118 543734.LCABL_11630 3.18e-106 306.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,3F3MR@33958|Lactobacillaceae 91061|Bacilli O Hydrolase, P-loop family ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE MHFCBNDO_01120 543734.LCABL_11640 1.71e-209 579.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,3F4J8@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ysdB - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 MHFCBNDO_01121 543734.LCABL_11650 2.34e-271 746.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,3F3KA@33958|Lactobacillaceae 91061|Bacilli CP ABC-2 family transporter protein ysdA - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 MHFCBNDO_01122 543734.LCABL_11660 4.66e-128 363.0 COG0847@1|root,COG0847@2|Bacteria,1V57H@1239|Firmicutes,4HI1V@91061|Bacilli,3F42Z@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T MHFCBNDO_01123 543734.LCABL_11670 8.14e-194 536.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli,3F4GK@33958|Lactobacillaceae 91061|Bacilli L exodeoxyribonuclease III exoA GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos MHFCBNDO_01124 543734.LCABL_11680 3.2e-211 584.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,3F40T@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C MHFCBNDO_01125 543734.LCABL_11690 0.0 1309.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter yvgP GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger MHFCBNDO_01126 543734.LCABL_11700 1.97e-124 354.0 COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,4HHAY@91061|Bacilli,3FCDZ@33958|Lactobacillaceae 91061|Bacilli K Cupin domain - - - - - - - - - - - - Cupin_2,HTH_3 MHFCBNDO_01127 543734.LCABL_11710 9.1e-263 719.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,3F40H@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 - iSB619.SA_RS05380 ABC_tran,TOBE_2 MHFCBNDO_01128 543734.LCABL_11720 1.44e-189 527.0 COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,4HAYS@91061|Bacilli,3F4CM@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease potB - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 MHFCBNDO_01129 543734.LCABL_11730 6.79e-186 518.0 COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli,3F3ZN@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease potC - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 MHFCBNDO_01130 543734.LCABL_11740 8.49e-267 729.0 COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli,3F3W1@33958|Lactobacillaceae 91061|Bacilli P ABC transporter potD - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSB619.SA_RS05395 SBP_bac_8 MHFCBNDO_01132 543734.LCABL_11760 0.0 1782.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HTQ4@91061|Bacilli,3FC0Z@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus pacL - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 MHFCBNDO_01133 543734.LCABL_11770 1.05e-143 406.0 COG1309@1|root,COG1309@2|Bacteria,1V3R8@1239|Firmicutes,4HBEK@91061|Bacilli,3F6RQ@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_N MHFCBNDO_01134 543734.LCABL_11780 2.68e-240 664.0 COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,3F40D@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 MHFCBNDO_01135 543734.LCABL_11790 3.66e-168 470.0 COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,4HBUK@91061|Bacilli,3F3VV@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_01136 543734.LCABL_11800 3.82e-195 542.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,3F4N3@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N MHFCBNDO_01137 543734.LCABL_11810 5.53e-217 603.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,3F41C@33958|Lactobacillaceae 91061|Bacilli S YbbR-like protein ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR MHFCBNDO_01138 543734.LCABL_11820 0.0 885.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,3F3W5@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV MHFCBNDO_01139 543734.LCABL_11830 0.0 1159.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,3F467@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS MHFCBNDO_01141 543734.LCABL_11840 0.0 1204.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,3F4ZV@33958|Lactobacillaceae 91061|Bacilli E Oligopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N MHFCBNDO_01142 543734.LCABL_11850 2.75e-105 305.0 COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,4HMDE@91061|Bacilli,3F57S@33958|Lactobacillaceae 91061|Bacilli S VanZ like family - - - - - - - - - - - - VanZ MHFCBNDO_01143 543734.LCABL_11860 5.85e-169 472.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,3F4WF@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg MHFCBNDO_01144 543734.LCABL_11870 1.02e-196 546.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,3F4HY@33958|Lactobacillaceae 91061|Bacilli NU Type II IV secretion system protein comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE MHFCBNDO_01145 543734.LCABL_11880 3.76e-217 600.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,3F3S9@33958|Lactobacillaceae 91061|Bacilli NU type II secretion system comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF MHFCBNDO_01146 1423732.BALS01000047_gene2628 1e-35 124.0 2BKDX@1|root,32EUM@2|Bacteria,1U7Q0@1239|Firmicutes,4IHMB@91061|Bacilli,3FA01@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - - MHFCBNDO_01148 568703.LGG_00991 3.32e-32 115.0 2AHWS@1|root,3189N@2|Bacteria,1U7TM@1239|Firmicutes,4IHR3@91061|Bacilli,3FA5S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01149 568703.LGG_00992 1.42e-24 99.8 29Q7R@1|root,30B6S@2|Bacteria,1U7MZ@1239|Firmicutes,4IHJ8@91061|Bacilli,3F9XI@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - - MHFCBNDO_01151 543734.LCABL_11940 3.73e-239 657.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli,3F4CI@33958|Lactobacillaceae 91061|Bacilli L N-6 DNA Methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase MHFCBNDO_01152 543734.LCABL_11950 8.54e-81 242.0 2BH80@1|root,32B99@2|Bacteria,1U70M@1239|Firmicutes,4IGUY@91061|Bacilli,3F8TH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01153 543734.LCABL_11960 0.0 887.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease cycA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease MHFCBNDO_01154 543734.LCABL_11970 7.51e-191 528.0 COG0204@1|root,COG0204@2|Bacteria,1V6NX@1239|Firmicutes,4IQ5I@91061|Bacilli,3FBFU@33958|Lactobacillaceae 91061|Bacilli I Phosphate acyltransferases arbV - - - - - - - - - - - Acyltransferase MHFCBNDO_01155 543734.LCABL_11980 8.22e-212 583.0 COG1442@1|root,COG1442@2|Bacteria,1UY4M@1239|Firmicutes,4IEY6@91061|Bacilli,3F4YZ@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 8 arbx - - - - - - - - - - - Glyco_transf_8 MHFCBNDO_01156 543734.LCABL_11990 2.22e-231 636.0 COG1442@1|root,COG1442@2|Bacteria,1UY8Y@1239|Firmicutes,4HBAE@91061|Bacilli,3F4YJ@33958|Lactobacillaceae 91061|Bacilli M family 8 arbY - - - - - - - - - - - Glyco_transf_8 MHFCBNDO_01157 543734.LCABL_12000 2.65e-213 588.0 COG0204@1|root,COG0204@2|Bacteria,1V2F4@1239|Firmicutes,4IF2T@91061|Bacilli,3F5FU@33958|Lactobacillaceae 91061|Bacilli I Phosphate acyltransferases arbZ - - - - - - - - - - - Acyltransferase MHFCBNDO_01158 543734.LCABL_12010 0.0 1553.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,3F3RU@33958|Lactobacillaceae 91061|Bacilli G alpha-galactosidase rafA - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase MHFCBNDO_01160 1423816.BACQ01000022_gene760 1.43e-273 748.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family sip - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase MHFCBNDO_01161 1405498.SSIM_09640 3.06e-06 54.7 COG3655@1|root,COG3655@2|Bacteria,1VKVP@1239|Firmicutes,4HRJ4@91061|Bacilli,4H03P@90964|Staphylococcaceae 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 MHFCBNDO_01163 568703.LGG_02888 1.39e-40 134.0 2BPNT@1|root,32IFV@2|Bacteria,1U81M@1239|Firmicutes,4IHZ0@91061|Bacilli,3FAF0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01164 543734.LCABL_30830 6.39e-25 92.8 29QI2@1|root,30BHH@2|Bacteria,1U84R@1239|Firmicutes,4II26@91061|Bacilli,3FAIV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01165 543734.LCABL_30840 1.17e-30 108.0 29QP0@1|root,30BNN@2|Bacteria,1U8DG@1239|Firmicutes,4IIBE@91061|Bacilli,3FAV3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01167 543734.LCABL_30860 5.47e-33 114.0 2AIKE@1|root,3192N@2|Bacteria,1U847@1239|Firmicutes,4II1N@91061|Bacilli,3FAIA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01168 543734.LCABL_30870 9.7e-189 525.0 COG3598@1|root,COG3598@2|Bacteria,1VVT1@1239|Firmicutes,4ITNM@91061|Bacilli,3FBJ8@33958|Lactobacillaceae 91061|Bacilli L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - PriCT_1,Prim-Pol MHFCBNDO_01169 543734.LCABL_30880 0.0 1033.0 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,3FCFD@33958|Lactobacillaceae 91061|Bacilli S Phage plasmid primase, P4 - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol MHFCBNDO_01170 1423816.BACQ01000022_gene751 6.31e-68 206.0 29PE6@1|root,30ACC@2|Bacteria,1U6GF@1239|Firmicutes,4IG8K@91061|Bacilli,3F7VC@33958|Lactobacillaceae 91061|Bacilli S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join MHFCBNDO_01172 1273712.R9QSU8_9CAUD 9.92e-27 103.0 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QKTX@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - MHFCBNDO_01173 1423816.BACQ01000022_gene749 3.15e-103 299.0 COG3747@1|root,COG3747@2|Bacteria,1VJ8S@1239|Firmicutes,4HQ9R@91061|Bacilli,3F4WP@33958|Lactobacillaceae 91061|Bacilli L Phage terminase, small subunit terS - - - - - - - - - - - Terminase_4 MHFCBNDO_01174 568703.LGG_02898 0.0 1077.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,3F51U@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name terL - - - - - - - - - - - Terminase_1 MHFCBNDO_01175 568703.LGG_02899 8.61e-29 103.0 2BTIA@1|root,32NQT@2|Bacteria,1U8EJ@1239|Firmicutes,4IICE@91061|Bacilli,3FAWA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01176 1423816.BACQ01000022_gene745 3.03e-278 761.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,4HHWD@91061|Bacilli,3F42D@33958|Lactobacillaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal MHFCBNDO_01177 543734.LCABL_30950 0.0 977.0 COG3740@1|root,COG4653@1|root,COG3740@2|Bacteria,COG4653@2|Bacteria,1TSYM@1239|Firmicutes,4HE4V@91061|Bacilli,3F5ZB@33958|Lactobacillaceae 91061|Bacilli S Phage capsid family - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78,Phage_capsid MHFCBNDO_01178 543734.LCABL_30960 8.23e-62 189.0 28TB1@1|root,2ZFJJ@2|Bacteria,1VGRD@1239|Firmicutes,4HS56@91061|Bacilli,3F8AP@33958|Lactobacillaceae 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 MHFCBNDO_01180 543734.LCABL_30970 2.3e-23 89.0 2A7T8@1|root,30WSA@2|Bacteria,1U6PB@1239|Firmicutes,4IGGB@91061|Bacilli,3F8SR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01181 1423732.BALS01000106_gene437 1.4e-35 122.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein ytgB - - - - - - - - - - - Transgly_assoc MHFCBNDO_01183 543734.LCABL_12040 5.39e-92 268.0 COG5658@1|root,2ZY3R@2|Bacteria,1VKM4@1239|Firmicutes,4I0CM@91061|Bacilli,3F6IB@33958|Lactobacillaceae 91061|Bacilli S SdpI/YhfL protein family - - - - - - - - - - - - SdpI MHFCBNDO_01184 543734.LCABL_12050 3.55e-174 485.0 COG0745@1|root,COG0745@2|Bacteria,1TQUQ@1239|Firmicutes,4HAXP@91061|Bacilli,3F3QZ@33958|Lactobacillaceae 91061|Bacilli K response regulator yclJ - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C MHFCBNDO_01185 543734.LCABL_12060 0.0 940.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4H9UD@91061|Bacilli,3F3Z4@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA MHFCBNDO_01186 1423816.BACQ01000022_gene737 1.34e-96 284.0 COG3153@1|root,COG3153@2|Bacteria,1W0Z5@1239|Firmicutes,4HZAD@91061|Bacilli,3FBB4@33958|Lactobacillaceae 91061|Bacilli S acetyltransferase - - - - - - - - - - - - Acetyltransf_1 MHFCBNDO_01187 568703.LGG_01006 5.2e-20 82.0 29QKN@1|root,30BKA@2|Bacteria,1U89K@1239|Firmicutes,4II7H@91061|Bacilli,3FAQS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01188 543734.LCABL_12100 7.36e-94 274.0 COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,4HFRC@91061|Bacilli,3F6TJ@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0735 family pheB - 5.4.99.5 ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27910 ACT,ACT_4 MHFCBNDO_01189 1423816.BACQ01000022_gene734 1.53e-88 263.0 29Q3G@1|root,30B24@2|Bacteria,1U7EM@1239|Firmicutes,4IHAG@91061|Bacilli,3F9HE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01190 543734.LCABL_12130 8.56e-74 221.0 28WF1@1|root,2ZIF8@2|Bacteria,1W2PF@1239|Firmicutes,4HZUK@91061|Bacilli,3F8BE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01191 543734.LCABL_12140 0.0 872.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,3F3WN@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA polymerase type-Y family polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH MHFCBNDO_01193 543734.LCABL_12160 3.59e-266 731.0 COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,3FBEE@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic tcaA - - ko:K21463 - - - - ko00000 - - - zf-ribbon_3,zinc_ribbon_2 MHFCBNDO_01194 543734.LCABL_12170 3.51e-180 502.0 COG2755@1|root,COG2755@2|Bacteria,1VIWQ@1239|Firmicutes,4HPR5@91061|Bacilli,3F8I7@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL,Lipase_GDSL_2 MHFCBNDO_01195 543734.LCABL_12180 5.65e-46 150.0 COG4269@1|root,COG4269@2|Bacteria,1VA3P@1239|Firmicutes,4HK0T@91061|Bacilli,3F733@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF898) - - - - - - - - - - - - DUF898 MHFCBNDO_01197 543734.LCABL_12190 0.0 1466.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3F400@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C MHFCBNDO_01198 543734.LCABL_12200 0.0 1315.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,3F43C@33958|Lactobacillaceae 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 MHFCBNDO_01199 543734.LCABL_12210 4.26e-271 742.0 COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,3F3KI@33958|Lactobacillaceae 91061|Bacilli S sex pheromone camS - - - - - - - - - - - CamS MHFCBNDO_01200 543734.LCABL_12220 3.61e-61 188.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,3F7XB@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln MHFCBNDO_01201 543734.LCABL_12230 0.0 933.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,3F4BK@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase MHFCBNDO_01202 543734.LCABL_12240 0.0 961.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,3F44H@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey MHFCBNDO_01203 543734.LCABL_12250 4.97e-248 681.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,3F447@33958|Lactobacillaceae 91061|Bacilli G Lipid kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat MHFCBNDO_01204 543734.LCABL_12260 0.0 894.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F41R@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_2 - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr MHFCBNDO_01205 543734.LCABL_12270 9.24e-281 769.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,3F4F9@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator yttB - - - - - - - - - - - MFS_1 MHFCBNDO_01206 543734.LCABL_12280 5.1e-190 528.0 COG0561@1|root,COG0561@2|Bacteria,1VAFW@1239|Firmicutes,4HWQV@91061|Bacilli,3FC8C@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 MHFCBNDO_01207 543734.LCABL_12290 2.44e-210 581.0 COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,4HDT2@91061|Bacilli,3F59Q@33958|Lactobacillaceae 91061|Bacilli S Polyphosphate nucleotide phosphotransferase, PPK2 family - - - - - - - - - - - - PPK2 MHFCBNDO_01208 543734.LCABL_12300 0.0 1275.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F9J0@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N MHFCBNDO_01209 543734.LCABL_12310 0.0 916.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F4D4@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1,MFS_3,Sugar_tr MHFCBNDO_01210 543734.LCABL_12320 3.04e-84 249.0 COG0454@1|root,COG0456@2|Bacteria,1VBAA@1239|Firmicutes,4HN0D@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 MHFCBNDO_01211 543734.LCABL_12330 2.87e-213 588.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,3F4II@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 yitS - - - - - - - - - - - DegV MHFCBNDO_01212 543734.LCABL_12340 1.37e-165 469.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli,3F4HV@33958|Lactobacillaceae 91061|Bacilli O prohibitin homologues hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 MHFCBNDO_01213 543734.LCABL_12350 1.24e-39 131.0 29PRV@1|root,30AQ2@2|Bacteria,1U6Z0@1239|Firmicutes,4IGT9@91061|Bacilli,3F8R4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01214 543734.LCABL_12360 1.63e-176 491.0 COG3757@1|root,COG3757@2|Bacteria,1V484@1239|Firmicutes,4HJNJ@91061|Bacilli,3FC1I@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,PG_binding_1 MHFCBNDO_01215 543734.LCABL_12370 9.39e-80 236.0 COG5294@1|root,COG5294@2|Bacteria,1VF0I@1239|Firmicutes,4HPC2@91061|Bacilli,3F83V@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 MHFCBNDO_01216 543734.LCABL_12380 1.9e-79 236.0 2EGZM@1|root,33ARR@2|Bacteria,1VNS7@1239|Firmicutes,4HSZW@91061|Bacilli,3F83W@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4828) - - - - - - - - - - - - DUF4828 MHFCBNDO_01217 543734.LCABL_12390 2.21e-226 624.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,3F4EV@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase mocA - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C MHFCBNDO_01218 543734.LCABL_12400 4.41e-289 791.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,3F4K8@33958|Lactobacillaceae 91061|Bacilli L DEAD DEAH box helicase yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C MHFCBNDO_01219 543734.LCABL_12410 7.9e-74 222.0 COG1447@1|root,COG1447@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system chbA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0016043,GO:0016740,GO:0016772,GO:0016773,GO:0022607,GO:0022804,GO:0022857,GO:0034219,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0071702,GO:0071840,GO:0090563,GO:0090566,GO:1901264,GO:1902815 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - iECABU_c1320.ECABU_c17610,iECOK1_1307.ECOK1_1683,iECUMN_1333.ECUMN_2025,iNRG857_1313.NRG857_07575,iUMN146_1321.UM146_09345 PTS_IIA MHFCBNDO_01220 543734.LCABL_12420 4.49e-93 272.0 2DQNY@1|root,337UX@2|Bacteria,1VEZ0@1239|Firmicutes,4HPE2@91061|Bacilli,3F875@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF3284) - - - - - - - - - - - - DUF3284 MHFCBNDO_01222 1291743.LOSG293_160010 4.16e-07 57.8 arCOG05209@1|root,31PIN@2|Bacteria,1V5G2@1239|Firmicutes,4HIRV@91061|Bacilli,3F6X9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01223 543734.LCABL_12450 0.0 1162.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3F4PY@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind MHFCBNDO_01224 543734.LCABL_12460 1.41e-306 834.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,3F53R@33958|Lactobacillaceae 91061|Bacilli E Thermophilic metalloprotease (M29) pepS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 MHFCBNDO_01225 543734.LCABL_12470 2.96e-144 406.0 COG1309@1|root,COG1309@2|Bacteria,1V8EE@1239|Firmicutes,4HJF2@91061|Bacilli,3FBGB@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N,WHG MHFCBNDO_01227 543734.LCABL_12480 0.0 899.0 COG4320@1|root,COG4320@2|Bacteria,1UCBA@1239|Firmicutes,4HBCI@91061|Bacilli,3F3JA@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2252) - - - ko:K13730 ko05100,map05100 - - - ko00000,ko00001 - - - DUF2252 MHFCBNDO_01228 543734.LCABL_12490 9.73e-230 634.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,3F4TC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0761 family rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB MHFCBNDO_01229 543734.LCABL_12500 1.24e-103 300.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli,3F6HY@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin fld - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 MHFCBNDO_01230 543734.LCABL_12510 1.16e-204 565.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,3F3MK@33958|Lactobacillaceae 91061|Bacilli E Methionine Aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 MHFCBNDO_01231 543734.LCABL_12520 3.04e-258 707.0 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,4HGSR@91061|Bacilli,3FBSG@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 MHFCBNDO_01233 568703.LGG_01060 1.02e-20 84.0 2BQ1G@1|root,32IVS@2|Bacteria,1U82T@1239|Firmicutes,4II07@91061|Bacilli,3FAGJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01234 543734.LCABL_12550 4.45e-253 694.0 COG1577@1|root,COG1577@2|Bacteria,1TPKP@1239|Firmicutes,4HC93@91061|Bacilli,3F3RZ@33958|Lactobacillaceae 91061|Bacilli I phosphomevalonate kinase mvaK2 - 2.7.4.2 ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R03245 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N MHFCBNDO_01235 543734.LCABL_12560 4.4e-215 594.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,3F45A@33958|Lactobacillaceae 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase MHFCBNDO_01236 1229520.ADIAL_1901 9.69e-149 468.0 COG1199@1|root,COG1199@2|Bacteria,1URXJ@1239|Firmicutes,4HF1N@91061|Bacilli,27HHM@186828|Carnobacteriaceae 91061|Bacilli KL HELICc2 - - - - - - - - - - - - Helicase_C_2,ResIII MHFCBNDO_01237 913848.AELK01000025_gene1955 3.18e-18 77.0 29PUH@1|root,30ASN@2|Bacteria,1U721@1239|Firmicutes,4IGWH@91061|Bacilli,3F8VN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01238 1133569.AHYZ01000171_gene111 1.02e-58 183.0 COG3436@1|root,COG3436@2|Bacteria,1VAJD@1239|Firmicutes,4HKCG@91061|Bacilli,3F7E1@33958|Lactobacillaceae 91061|Bacilli L PFAM IS66 Orf2 family protein XK27_01125 - - ko:K07484 - - - - ko00000 - - - TnpB_IS66 MHFCBNDO_01240 641146.HMPREF9020_01154 2.24e-300 819.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 MHFCBNDO_01241 543734.LCABL_12660 0.0 981.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 MHFCBNDO_01242 543734.LCABL_12670 0.0 1118.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system bglH - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC MHFCBNDO_01243 543734.LCABL_12680 1.23e-191 532.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HEI6@91061|Bacilli,3F6PD@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain licT2 - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD MHFCBNDO_01244 543734.LCABL_12690 0.0 1697.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HCR9@91061|Bacilli,3FC7P@33958|Lactobacillaceae 91061|Bacilli S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO MHFCBNDO_01245 543734.LCABL_12700 0.0 1105.0 COG5617@1|root,COG5617@2|Bacteria,1VS0Z@1239|Firmicutes,4HJQE@91061|Bacilli,3FBX8@33958|Lactobacillaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - PTPS_related MHFCBNDO_01246 543734.LCABL_12710 1.42e-218 603.0 COG1216@1|root,COG1216@2|Bacteria,1UHWE@1239|Firmicutes,4ISA4@91061|Bacilli,3F3JX@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 2 family protein yfdH - - ko:K12999 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 MHFCBNDO_01247 543734.LCABL_12720 8.56e-133 378.0 28T4I@1|root,2ZFDJ@2|Bacteria,1W6RG@1239|Firmicutes,4HZG4@91061|Bacilli,3F88M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - YkyA MHFCBNDO_01248 543734.LCABL_12730 8.49e-217 600.0 COG4129@1|root,COG4129@2|Bacteria,1TP2T@1239|Firmicutes,4HAWV@91061|Bacilli,3F54Y@33958|Lactobacillaceae 91061|Bacilli S Putative aromatic acid exporter C-terminal domain yqjA - - - - - - - - - - - ArAE_1,ArAE_1_C MHFCBNDO_01250 1423732.BALS01000024_gene2412 6.22e-43 139.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3F7FW@33958|Lactobacillaceae 91061|Bacilli K Cold shock protein cspC - - ko:K03704 - - - - ko00000,ko03000 - - - CSD MHFCBNDO_01251 543734.LCABL_12750 9.32e-107 308.0 COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,4HH45@91061|Bacilli,3F7GI@33958|Lactobacillaceae 91061|Bacilli K GNAT family yvbK - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 MHFCBNDO_01252 543734.LCABL_12760 2.4e-148 417.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIY4@91061|Bacilli,3F584@33958|Lactobacillaceae 91061|Bacilli NU mannosyl-glycoprotein acmA - 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,SH3_8,YceG MHFCBNDO_01253 543734.LCABL_12770 5.35e-133 377.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,3F49S@33958|Lactobacillaceae 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran MHFCBNDO_01254 543734.LCABL_12780 6.23e-303 828.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,3F3Y7@33958|Lactobacillaceae 91061|Bacilli F xanthine permease pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16169 - - - - ko00000,ko02000 2.A.40,2.A.40.3.1 - iSB619.SA_RS02140 Xan_ur_permease MHFCBNDO_01255 543734.LCABL_12790 1.29e-258 709.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,3F3YV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK2 - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp MHFCBNDO_01256 543734.LCABL_12800 9.74e-315 857.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,3F48P@33958|Lactobacillaceae 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 MHFCBNDO_01257 543734.LCABL_12810 7.65e-136 384.0 29PYD@1|root,30AWT@2|Bacteria,1U77H@1239|Firmicutes,4IH2B@91061|Bacilli,3F92N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01258 1423732.BALS01000024_gene2404 7.04e-136 389.0 29Z4F@1|root,30M23@2|Bacteria,1U7B2@1239|Firmicutes,4IH62@91061|Bacilli,3F98Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01259 543734.LCABL_12830 0.0 1463.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase MHFCBNDO_01260 543734.LCABL_12840 3.2e-143 404.0 COG4767@1|root,COG4767@2|Bacteria,1VK3A@1239|Firmicutes,4HPCD@91061|Bacilli,3F5EN@33958|Lactobacillaceae 91061|Bacilli V VanZ like family vanZ - - - - - - - - - - - VanZ MHFCBNDO_01261 543734.LCABL_12860 4.66e-196 544.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,3F4K2@33958|Lactobacillaceae 91061|Bacilli U sugar transport glcU GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659 - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport MHFCBNDO_01262 543734.LCABL_12870 0.0 890.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,3F3XK@33958|Lactobacillaceae 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI MHFCBNDO_01263 543734.LCABL_12880 8.89e-290 790.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HEI7@91061|Bacilli,3F5DJ@33958|Lactobacillaceae 91061|Bacilli L Pfam:Integrase_AP2 - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase MHFCBNDO_01264 543734.LCABL_12910 1.11e-41 136.0 2AI1X@1|root,318FN@2|Bacteria,1U7VR@1239|Firmicutes,4IHT4@91061|Bacilli,3FA8F@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01265 543734.LCABL_12920 1.1e-89 263.0 COG3871@1|root,COG3871@2|Bacteria,1V1KZ@1239|Firmicutes,4I1P9@91061|Bacilli,3F7W7@33958|Lactobacillaceae 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx MHFCBNDO_01266 1449343.JQLQ01000002_gene1500 2.33e-25 105.0 2F7D5@1|root,33ZU6@2|Bacteria,1VWPX@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - MHFCBNDO_01267 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_01268 568703.LGG_01093 4.18e-126 362.0 2DMIQ@1|root,32RV1@2|Bacteria,1VDPT@1239|Firmicutes,4HKU5@91061|Bacilli,3F6VC@33958|Lactobacillaceae 91061|Bacilli S Domain of Unknown Function with PDB structure (DUF3862) - - - - - - - - - - - - DUF3862 MHFCBNDO_01269 1423732.BALS01000070_gene2074 1.39e-91 268.0 COG2856@1|root,COG2856@2|Bacteria,1W1K0@1239|Firmicutes,4I17Z@91061|Bacilli 91061|Bacilli E Zn peptidase - - - - - - - - - - - - Peptidase_M78 MHFCBNDO_01270 568703.LGG_01095 1.42e-71 215.0 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HRBT@91061|Bacilli,3F85V@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_19,HTH_3 MHFCBNDO_01271 568703.LGG_01096 6.25e-47 150.0 2DQ3T@1|root,334M5@2|Bacteria,1UVU8@1239|Firmicutes,4II6I@91061|Bacilli,3FAPP@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 MHFCBNDO_01275 543734.LCABL_13020 1.82e-126 360.0 2ERS9@1|root,32C80@2|Bacteria,1U7E6@1239|Firmicutes,4IHA2@91061|Bacilli,3F9GF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01277 543734.LCABL_13030 4.92e-21 82.8 29QME@1|root,30BM2@2|Bacteria,1U8B1@1239|Firmicutes,4II91@91061|Bacilli,3FASG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01280 568703.LGG_01104 4.63e-180 504.0 COG3723@1|root,COG3723@2|Bacteria,1V0QW@1239|Firmicutes,4HBS2@91061|Bacilli,3F47A@33958|Lactobacillaceae 91061|Bacilli L RecT family - - - ko:K07455 - - - - ko00000,ko03400 - - - RecT MHFCBNDO_01281 568703.LGG_01105 6.3e-174 486.0 COG1074@1|root,COG1074@2|Bacteria,1V1UQ@1239|Firmicutes,4HGSG@91061|Bacilli,3F51S@33958|Lactobacillaceae 91061|Bacilli L PDDEXK-like domain of unknown function (DUF3799) pi112 - - - - - - - - - - - DUF3799 MHFCBNDO_01282 220668.lp_0643 1.12e-89 276.0 COG3935@1|root,COG3935@2|Bacteria,1V6IW@1239|Firmicutes,4HJ9G@91061|Bacilli,3FAFI@33958|Lactobacillaceae 91061|Bacilli L Domain of unknown function (DUF4373) - - - - - - - - - - - - DUF4373,DnaB_2,Rep_Org_C MHFCBNDO_01283 568703.LGG_01107 3.06e-92 271.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,3F66N@33958|Lactobacillaceae 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB MHFCBNDO_01285 257314.LJ_1453 6.14e-09 54.3 COG1476@1|root,COG1476@2|Bacteria,1VN6P@1239|Firmicutes,4HRNQ@91061|Bacilli 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 MHFCBNDO_01286 1423732.BALS01000098_gene1435 5.02e-60 189.0 29Q0P@1|root,30AZ5@2|Bacteria,1U7AM@1239|Firmicutes,4IH5K@91061|Bacilli,3F97Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01287 543734.LCABL_13130 6.07e-49 156.0 29Q9N@1|root,30B8R@2|Bacteria,1U7R2@1239|Firmicutes,4IHNC@91061|Bacilli,3FA1N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01288 39103.U5U799_9CAUD 9.27e-86 252.0 4QB0C@10239|Viruses,4QZIU@35237|dsDNA viruses no RNA stage,4QPK3@28883|Caudovirales,4QKQC@10699|Siphoviridae 10699|Siphoviridae S magnesium ion binding - - - - - - - - - - - - - MHFCBNDO_01290 1423732.BALS01000058_gene2831 6.27e-81 244.0 29Q9Z@1|root,30B93@2|Bacteria,1U7RI@1239|Firmicutes,4IHNV@91061|Bacilli,3FA2I@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1642) - - - - - - - - - - - - DUF1642 MHFCBNDO_01292 1423732.BALS01000058_gene2832 4.43e-23 93.2 29Q9M@1|root,30B8Q@2|Bacteria,1U7QY@1239|Firmicutes,4IHN8@91061|Bacilli,3FA1A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01294 1423816.BACQ01000027_gene954 3.38e-40 137.0 29Q9M@1|root,30B8Q@2|Bacteria,1U7QY@1239|Firmicutes,4IHN8@91061|Bacilli,3FA1A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01298 543734.LCABL_05720 7.91e-104 300.0 2DCNS@1|root,2ZESF@2|Bacteria,1W51N@1239|Firmicutes,4I1NU@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01300 146269.A8YQN3_9CAUD 1.18e-295 806.0 4QCT4@10239|Viruses,4QWIG@35237|dsDNA viruses no RNA stage,4QQW8@28883|Caudovirales,4QN4I@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - MHFCBNDO_01301 543734.LCABL_05780 5.39e-65 198.0 2BWYP@1|root,30AJY@2|Bacteria,1U6SS@1239|Firmicutes,4IGKB@91061|Bacilli,3F8F9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01302 543734.LCABL_13230 1.03e-120 346.0 COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,4HXMG@91061|Bacilli,3F6ZJ@33958|Lactobacillaceae 91061|Bacilli L Terminase small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 MHFCBNDO_01303 543734.LCABL_13240 6.83e-313 851.0 COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,4H9S2@91061|Bacilli,3F3NN@33958|Lactobacillaceae 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C MHFCBNDO_01304 543734.LCABL_13250 0.0 913.0 2DB9U@1|root,2Z7Z6@2|Bacteria,1TR67@1239|Firmicutes,4HCTZ@91061|Bacilli,3FB8U@33958|Lactobacillaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_prot_Gp6 MHFCBNDO_01305 543734.LCABL_13260 6.8e-227 626.0 COG2369@1|root,COG2369@2|Bacteria,1U6KJ@1239|Firmicutes,4HGZW@91061|Bacilli,3F3Z8@33958|Lactobacillaceae 91061|Bacilli S head morphogenesis protein, SPP1 gp7 family - - - - - - - - - - - - Phage_Mu_F MHFCBNDO_01308 568703.LGG_01128 8.26e-105 308.0 2DNT1@1|root,32YZX@2|Bacteria,1VEET@1239|Firmicutes,4HQ00@91061|Bacilli,3F7QQ@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4355) - - - - - - - - - - - - DUF4355 MHFCBNDO_01309 543734.LCABL_13280 6.27e-67 203.0 2EHA7@1|root,33B23@2|Bacteria,1VK8N@1239|Firmicutes,4HXXJ@91061|Bacilli,3F87M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01310 543734.LCABL_13300 1.37e-246 677.0 2DB75@1|root,2Z7JY@2|Bacteria,1TSI8@1239|Firmicutes,4IRVK@91061|Bacilli,3F5Z9@33958|Lactobacillaceae 91061|Bacilli S Phage major capsid protein E - - - - - - - - - - - - Phage_cap_E MHFCBNDO_01311 543734.LCABL_13310 1.02e-38 133.0 2DGA1@1|root,2ZV36@2|Bacteria,1U6Y3@1239|Firmicutes,4IGS9@91061|Bacilli,3F8PQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01312 543734.LCABL_13320 1.14e-229 630.0 28K9K@1|root,2Z9X3@2|Bacteria,1UYR8@1239|Firmicutes,4HENS@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - PqqD MHFCBNDO_01313 543734.LCABL_13330 6.46e-83 245.0 2EKJJ@1|root,33E9D@2|Bacteria,1VN9C@1239|Firmicutes,4HR20@91061|Bacilli,3F7K9@33958|Lactobacillaceae 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 MHFCBNDO_01314 568703.LGG_01131 7.78e-66 200.0 2E86K@1|root,332JW@2|Bacteria,1VIHK@1239|Firmicutes,4HZJB@91061|Bacilli,3F8A2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01315 543734.LCABL_13350 1.17e-70 214.0 2CIV5@1|root,32ZS6@2|Bacteria,1VFPA@1239|Firmicutes,4HQWN@91061|Bacilli,3F8P3@33958|Lactobacillaceae 91061|Bacilli S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like MHFCBNDO_01316 543734.LCABL_13360 2.75e-91 267.0 2EIM8@1|root,33CCI@2|Bacteria,1VMSE@1239|Firmicutes,4HRDA@91061|Bacilli,3F7YS@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 MHFCBNDO_01317 568703.LGG_01134 5.94e-134 380.0 2F0XZ@1|root,33TZM@2|Bacteria,1VUVY@1239|Firmicutes,4HVU9@91061|Bacilli,3F76N@33958|Lactobacillaceae 91061|Bacilli S Phage tail tube protein - - - - - - - - - - - - Phage_tail_2 MHFCBNDO_01318 568703.LGG_01135 3.3e-47 152.0 2EBTF@1|root,333J2@2|Bacteria,1VHHD@1239|Firmicutes,4HQFJ@91061|Bacilli,3FBPF@33958|Lactobacillaceae 91061|Bacilli S Phage tail assembly chaperone protein, TAC - - - - - - - - - - - - Phage_TAC_12 MHFCBNDO_01319 568703.LGG_01136 1.57e-73 221.0 2EHS8@1|root,33BHZ@2|Bacteria,1VKIN@1239|Firmicutes,4HR6E@91061|Bacilli,3F7N3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01320 568703.LGG_01137 0.0 1097.0 COG5412@1|root,COG5412@2|Bacteria,1W2PZ@1239|Firmicutes,4I175@91061|Bacilli,3F5MC@33958|Lactobacillaceae 91061|Bacilli S phage tail tape measure protein - - - - - - - - - - - - - MHFCBNDO_01321 543734.LCABL_13410 6.75e-171 510.0 COG4722@1|root,COG4722@2|Bacteria,1UVV4@1239|Firmicutes,4ICSW@91061|Bacilli,3F8C6@33958|Lactobacillaceae 91061|Bacilli S Phage tail protein - - - - - - - - - - - - Sipho_tail MHFCBNDO_01322 568703.LGG_01139 2.83e-193 580.0 COG4926@1|root,COG4926@2|Bacteria,1TTBV@1239|Firmicutes,4HBWT@91061|Bacilli 91061|Bacilli S cellulase activity - - - - - - - - - - - - Prophage_tail MHFCBNDO_01323 568703.LGG_01140 1.09e-13 68.2 2BJKG@1|root,32DXP@2|Bacteria,1U7KU@1239|Firmicutes,4IHHX@91061|Bacilli,3F9VT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01325 146269.A8YQK4_9CAUD 1.72e-83 247.0 4QHK5@10239|Viruses,4QZM7@35237|dsDNA viruses no RNA stage,4QTTX@28883|Caudovirales,4QMA9@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - MHFCBNDO_01327 1423732.BALS01000111_gene29 1.98e-84 251.0 2FDCN@1|root,345EF@2|Bacteria,1W0SS@1239|Firmicutes,4HXYE@91061|Bacilli,3F8B6@33958|Lactobacillaceae 91061|Bacilli S Bacteriophage holin of superfamily 6 (Holin_LLH) - - - - - - - - - - - - Phage_holin_6_1 MHFCBNDO_01328 1423816.BACQ01000026_gene927 6.97e-227 631.0 COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V16P@1239|Firmicutes,4HF99@91061|Bacilli,3FC13@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25,LysM,SH3_5 MHFCBNDO_01329 543734.LCABL_13490 5.83e-177 494.0 28KYP@1|root,2ZAE6@2|Bacteria,1V775@1239|Firmicutes,4HMWB@91061|Bacilli,3F6AR@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function DUF1829 - - - - - - - - - - - - DUF1828,DUF1829 MHFCBNDO_01330 543734.LCABL_13500 2.12e-63 193.0 COG1359@1|root,COG1359@2|Bacteria,1VG4T@1239|Firmicutes,4HPNQ@91061|Bacilli,3F7H6@33958|Lactobacillaceae 91061|Bacilli S Antibiotic biosynthesis monooxygenase ycnE GO:0003674,GO:0003824 - - - - - - - - - - ABM MHFCBNDO_01332 543734.LCABL_13520 3.82e-194 539.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HHHQ@91061|Bacilli,3F4MB@33958|Lactobacillaceae 91061|Bacilli F DNA/RNA non-specific endonuclease - - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 MHFCBNDO_01333 543734.LCABL_13530 5.49e-71 224.0 COG2433@1|root,COG2433@2|Bacteria,1VH0K@1239|Firmicutes,4ITND@91061|Bacilli,3FBX9@33958|Lactobacillaceae 91061|Bacilli S Pfam Transposase IS66 - - - - - - - - - - - - - MHFCBNDO_01334 543734.LCABL_13550 1.87e-292 796.0 COG0438@1|root,COG0438@2|Bacteria,1VIZB@1239|Firmicutes,4HU4N@91061|Bacilli,3F9Q1@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glyco_trans_1_4 MHFCBNDO_01335 543734.LCABL_13560 3.64e-219 604.0 COG0673@1|root,COG0673@2|Bacteria,1UZRV@1239|Firmicutes,4HEWB@91061|Bacilli,3F4BX@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold ysjB - - ko:K03810 - - - - ko00000 - - - GFO_IDH_MocA MHFCBNDO_01336 543734.LCABL_13570 5.68e-110 316.0 COG0590@1|root,COG0590@2|Bacteria,1V7G0@1239|Firmicutes,4HMR9@91061|Bacilli,3F6S6@33958|Lactobacillaceae 91061|Bacilli FJ MafB19-like deaminase guaD - - - - - - - - - - - MafB19-deam,dCMP_cyt_deam_1 MHFCBNDO_01338 543734.LCABL_13600 4.26e-103 299.0 COG3476@1|root,COG3476@2|Bacteria,1V896@1239|Firmicutes,4HK1B@91061|Bacilli,3F6ED@33958|Lactobacillaceae 91061|Bacilli T TspO/MBR family tspO - - ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 - - - ko00000,ko00001,ko02000 9.A.24 - - TspO_MBR MHFCBNDO_01339 1423732.BALS01000006_gene697 1.53e-19 79.7 29PYH@1|root,30AWY@2|Bacteria,1U77Q@1239|Firmicutes,4IH2I@91061|Bacilli,3F930@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01340 543734.LCABL_13620 3.11e-271 744.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,3F4F9@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator yttB - - - - - - - - - - - MFS_1 MHFCBNDO_01341 543734.LCABL_13630 4.36e-136 385.0 COG3548@1|root,COG3548@2|Bacteria,1U544@1239|Firmicutes,4IEVF@91061|Bacilli,3F4HQ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 MHFCBNDO_01342 543734.LCABL_13640 0.0 986.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD2 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 MHFCBNDO_01345 543734.LCABL_13680 4.1e-163 457.0 COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HD4C@91061|Bacilli,3F50R@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family pgm7 - - - - - - - - - - - His_Phos_1 MHFCBNDO_01346 543734.LCABL_13690 6.41e-155 434.0 COG1309@1|root,COG1309@2|Bacteria,1V6CF@1239|Firmicutes,4HJIC@91061|Bacilli,3FCEJ@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N MHFCBNDO_01347 543734.LCABL_13700 0.0 1093.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ycfI - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran MHFCBNDO_01348 543734.LCABL_13710 0.0 1206.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yfiC - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran MHFCBNDO_01349 543734.LCABL_13720 7.15e-179 498.0 COG0431@1|root,COG0431@2|Bacteria,1VBJA@1239|Firmicutes,4HSVK@91061|Bacilli,3F41J@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red MHFCBNDO_01350 543734.LCABL_13730 1.07e-207 574.0 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli,3F62I@33958|Lactobacillaceae 91061|Bacilli S glyoxalase catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase MHFCBNDO_01351 543734.LCABL_13740 1.24e-249 684.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,3FBDZ@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase ampC - - - - - - - - - - - Beta-lactamase MHFCBNDO_01352 543734.LCABL_13750 0.0 903.0 COG0770@1|root,COG0770@2|Bacteria,1TRG9@1239|Firmicutes,4HAMY@91061|Bacilli,3FBS5@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF1727) murE2 - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - DUF1727,Mur_ligase_M MHFCBNDO_01353 543734.LCABL_13760 4.41e-143 403.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,3F4UE@33958|Lactobacillaceae 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK MHFCBNDO_01354 543734.LCABL_13770 8.62e-252 691.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,3F3Q0@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 MHFCBNDO_01355 543734.LCABL_13780 2.32e-196 544.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,3F460@33958|Lactobacillaceae 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS MHFCBNDO_01356 543734.LCABL_13790 4.89e-238 654.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,3F3T1@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC MHFCBNDO_01357 543734.LCABL_13800 2.13e-296 808.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,3F4C1@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT MHFCBNDO_01358 543734.LCABL_13810 3.05e-145 409.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,3F4M0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase MHFCBNDO_01359 543734.LCABL_13820 1.23e-162 456.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,3F3RE@33958|Lactobacillaceae 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A MHFCBNDO_01360 543734.LCABL_13830 2.57e-37 125.0 COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli,3F82A@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C MHFCBNDO_01361 543734.LCABL_13840 1.13e-83 250.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,3F5M8@33958|Lactobacillaceae 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B MHFCBNDO_01362 543734.LCABL_13850 3.37e-117 336.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,3F5TZ@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP MHFCBNDO_01363 543734.LCABL_13860 0.0 983.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,3F3R4@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N MHFCBNDO_01364 543734.LCABL_13870 1.92e-211 585.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,3F40E@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt MHFCBNDO_01365 543734.LCABL_13880 0.0 896.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,3F3TF@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N MHFCBNDO_01366 543734.LCABL_13890 1.88e-91 268.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,3F6I6@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N MHFCBNDO_01367 543734.LCABL_13900 8.38e-42 137.0 COG4836@1|root,COG4836@2|Bacteria,1U2FQ@1239|Firmicutes,4HNZX@91061|Bacilli,3F831@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1146) - - - - - - - - - - - - DUF1146 MHFCBNDO_01368 543734.LCABL_13910 4.12e-228 629.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F463@33958|Lactobacillaceae 91061|Bacilli D Cell shape determining protein MreB Mrl mbl - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl MHFCBNDO_01369 568703.LGG_01189 1.37e-26 97.8 2EK0E@1|root,33DQZ@2|Bacteria,1VMAH@1239|Firmicutes,4I4NP@91061|Bacilli,3F8Q0@33958|Lactobacillaceae 91061|Bacilli S DNA-directed RNA polymerase subunit beta - - - - - - - - - - - - EpuA MHFCBNDO_01370 543734.LCABL_13930 1.14e-72 217.0 COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli,3F7H1@33958|Lactobacillaceae 91061|Bacilli S Could be involved in insertion of integral membrane proteins into the membrane ytjA - - ko:K08998 - - - - ko00000 - - - Haemolytic MHFCBNDO_01371 1423816.BACQ01000017_gene611 8.37e-42 137.0 2BQ47@1|root,30ACR@2|Bacteria,1U6GX@1239|Firmicutes,4IG94@91061|Bacilli,3F7W8@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2969) - - - - - - - - - - - - DUF2969 MHFCBNDO_01372 543734.LCABL_13950 1.41e-285 780.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,3F4J4@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE MHFCBNDO_01373 543734.LCABL_13960 4.19e-65 198.0 COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,3F7WB@33958|Lactobacillaceae 91061|Bacilli E glycine cleavage gcsH2 - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H MHFCBNDO_01374 543734.LCABL_13970 1.88e-268 736.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 MHFCBNDO_01375 543734.LCABL_13980 3.79e-186 518.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3F3WP@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 MHFCBNDO_01377 543734.LCABL_13990 8.04e-192 533.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3F3WP@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 MHFCBNDO_01378 543734.LCABL_14000 2.09e-243 669.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,3F3U5@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL MHFCBNDO_01379 543734.LCABL_14010 5.35e-149 421.0 COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,4HBEV@91061|Bacilli,3F48A@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 MHFCBNDO_01380 543734.LCABL_14020 4.15e-184 511.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,3F3XT@33958|Lactobacillaceae 91061|Bacilli O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran MHFCBNDO_01381 543734.LCABL_14030 3.88e-243 668.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,3F4BR@33958|Lactobacillaceae 91061|Bacilli O FeS assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 MHFCBNDO_01382 543734.LCABL_14040 4.87e-280 766.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,3F3UP@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 MHFCBNDO_01383 543734.LCABL_14050 4.94e-103 298.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,3F6WP@33958|Lactobacillaceae 91061|Bacilli C SUF system FeS assembly protein, NifU family nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N MHFCBNDO_01384 543734.LCABL_14060 0.0 962.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,3F44I@33958|Lactobacillaceae 91061|Bacilli O assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 MHFCBNDO_01385 1423732.BALS01000006_gene651 4.73e-31 109.0 29QHS@1|root,30BH8@2|Bacteria,1U84C@1239|Firmicutes,4II1T@91061|Bacilli,3FAIG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01386 543734.LCABL_14080 9.85e-88 257.0 COG5506@1|root,COG5506@2|Bacteria,1V8ID@1239|Firmicutes,4HJTQ@91061|Bacilli,3F7A5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1694) - - - - - - - - - - - - DUF1694 MHFCBNDO_01387 543734.LCABL_14090 3.03e-231 636.0 29SNM@1|root,30DU7@2|Bacteria,1V3Z9@1239|Firmicutes,4HHKX@91061|Bacilli,3F3VM@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 MHFCBNDO_01388 543734.LCABL_14100 2.13e-149 421.0 COG0637@1|root,COG0637@2|Bacteria,1VA1U@1239|Firmicutes,4HMKX@91061|Bacilli 91061|Bacilli S HAD hydrolase, family IA, variant 3 yhfA - - - - - - - - - - - HAD_2 MHFCBNDO_01389 543734.LCABL_14110 2.7e-200 556.0 COG1476@1|root,COG1476@2|Bacteria,1VMYH@1239|Firmicutes,4ISF0@91061|Bacilli,3F5QH@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3,TPR_8 MHFCBNDO_01390 543734.LCABL_14120 2.86e-108 312.0 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,3F68T@33958|Lactobacillaceae 91061|Bacilli T universal stress protein uspA - - - - - - - - - - - Usp MHFCBNDO_01391 543734.LCABL_14130 1.65e-52 166.0 2BNXR@1|root,32HMR@2|Bacteria,1U7ZC@1239|Firmicutes,4IHWQ@91061|Bacilli,3FACP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01392 543734.LCABL_14140 1.66e-306 836.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3WF@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N MHFCBNDO_01393 543734.LCABL_14150 0.0 1261.0 COG1181@1|root,COG2918@1|root,COG1181@2|Bacteria,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli,3F506@33958|Lactobacillaceae 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshAB - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase MHFCBNDO_01394 543734.LCABL_14160 1.13e-98 286.0 COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli,3F64D@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1694) XK27_05190 - - - - - - - - - - - DUF1694 MHFCBNDO_01395 543734.LCABL_14170 5.99e-143 403.0 COG4493@1|root,COG4493@2|Bacteria,1UY83@1239|Firmicutes,4HEDB@91061|Bacilli,3F62K@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0637 family yktB - - - - - - - - - - - DUF1054 MHFCBNDO_01396 543734.LCABL_14180 1.02e-158 444.0 COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,4HBD6@91061|Bacilli,3F4UB@33958|Lactobacillaceae 91061|Bacilli E Serine dehydratase beta chain sdaAB - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - ACT,SDH_beta MHFCBNDO_01397 543734.LCABL_14190 4.62e-193 537.0 COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli,3F3X8@33958|Lactobacillaceae 91061|Bacilli E L-serine dehydratase, iron-sulfur-dependent, alpha subunit sdaAA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha MHFCBNDO_01398 543734.LCABL_14200 1.89e-157 442.0 COG0406@1|root,COG0406@2|Bacteria 2|Bacteria G alpha-ribazole phosphatase activity - - - - - - - - - - - - His_Phos_1 MHFCBNDO_01399 543734.LCABL_14210 2.82e-197 546.0 COG0225@1|root,COG0225@2|Bacteria,1TS05@1239|Firmicutes,4HAPI@91061|Bacilli,3FC52@33958|Lactobacillaceae 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine mrsA1 - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - EntA_Immun,PMSR MHFCBNDO_01400 543734.LCABL_14220 1.66e-218 603.0 COG1028@1|root,COG1028@2|Bacteria,1VSDG@1239|Firmicutes,4HUM6@91061|Bacilli,3FB7Z@33958|Lactobacillaceae 91061|Bacilli IQ NAD dependent epimerase/dehydratase family - - - - - - - - - - - - adh_short MHFCBNDO_01401 543734.LCABL_14230 2.93e-178 496.0 COG3201@1|root,COG3201@2|Bacteria,1VE5T@1239|Firmicutes,4HMNW@91061|Bacilli,3F3MB@33958|Lactobacillaceae 91061|Bacilli H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter MHFCBNDO_01402 543734.LCABL_14240 2.05e-173 483.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,3F488@33958|Lactobacillaceae 91061|Bacilli F deoxynucleoside kinase - - - - - - - - - - - - dNK MHFCBNDO_01403 543734.LCABL_14250 8.16e-203 560.0 COG1387@1|root,COG1387@2|Bacteria,1V77D@1239|Firmicutes,4HHQX@91061|Bacilli,3F6HU@33958|Lactobacillaceae 91061|Bacilli E Histidinol phosphatase and related hydrolases of the PHP family hisK - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - - MHFCBNDO_01404 543734.LCABL_14260 0.0 1075.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 MHFCBNDO_01405 543734.LCABL_14270 3.55e-202 561.0 COG0642@1|root,COG2205@2|Bacteria,1UZKD@1239|Firmicutes,4ITNE@91061|Bacilli,3FBXA@33958|Lactobacillaceae 91061|Bacilli T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA MHFCBNDO_01406 543734.LCABL_14280 2.69e-156 439.0 COG0745@1|root,COG0745@2|Bacteria,1UYA6@1239|Firmicutes,4IQ4T@91061|Bacilli,3F6RJ@33958|Lactobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C MHFCBNDO_01407 543734.LCABL_14290 1.17e-217 601.0 COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HAGA@91061|Bacilli,3FC3R@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system bcrA - - ko:K01990,ko:K19309 ko02010,map02010 M00254,M00747 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.131.1 - - ABC_tran MHFCBNDO_01408 543734.LCABL_14300 1.8e-142 406.0 2EGU7@1|root,33AKD@2|Bacteria,1VMES@1239|Firmicutes,4HXVU@91061|Bacilli,3F7PT@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_4 MHFCBNDO_01409 543734.LCABL_14310 3.45e-206 570.0 COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HAZB@91061|Bacilli,3F3VP@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate MHFCBNDO_01410 543734.LCABL_14320 1.11e-101 293.0 COG1917@1|root,COG1917@2|Bacteria,1V3TP@1239|Firmicutes,4HWR6@91061|Bacilli,3FBIH@33958|Lactobacillaceae 91061|Bacilli S Cupin domain yphH - - - - - - - - - - - Cupin_2 MHFCBNDO_01411 543734.LCABL_14330 1.07e-72 218.0 COG0599@1|root,COG0599@2|Bacteria,1VWSB@1239|Firmicutes,4HJ1V@91061|Bacilli,3F736@33958|Lactobacillaceae 91061|Bacilli S decarboxylase yphJ - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD MHFCBNDO_01412 543734.LCABL_14340 2.72e-149 420.0 COG0702@1|root,COG0702@2|Bacteria,1V7A7@1239|Firmicutes,4HIII@91061|Bacilli,3F63T@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10 MHFCBNDO_01413 543734.LCABL_14350 1.94e-54 170.0 COG0640@1|root,COG0640@2|Bacteria,1VF0J@1239|Firmicutes,4HP0R@91061|Bacilli,3F8E3@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 MHFCBNDO_01414 543734.LCABL_14360 2.25e-156 437.0 COG0625@1|root,COG0625@2|Bacteria,1V559@1239|Firmicutes,4HRFX@91061|Bacilli,3F6C9@33958|Lactobacillaceae 91061|Bacilli O Glutathione S-transferase, C-terminal domain gst - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_3,GST_N,GST_N_2 MHFCBNDO_01415 543734.LCABL_14370 1.5e-142 403.0 COG2207@1|root,COG2207@2|Bacteria,1TSHF@1239|Firmicutes,4HFC7@91061|Bacilli,3F6S2@33958|Lactobacillaceae 91061|Bacilli K Psort location Cytoplasmic, score - - - - - - - - - - - - SAP MHFCBNDO_01416 543734.LCABL_14380 1.65e-211 584.0 COG0454@1|root,COG0456@2|Bacteria,1V7Z2@1239|Firmicutes,4HPF8@91061|Bacilli,3F7HG@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 MHFCBNDO_01417 543734.LCABL_14390 4.14e-113 324.0 COG0454@1|root,COG0456@2|Bacteria,1UI2W@1239|Firmicutes,4ISXQ@91061|Bacilli,3F8D7@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 MHFCBNDO_01418 543734.LCABL_14420 8.05e-197 546.0 COG1307@1|root,COG1307@2|Bacteria,1TYCV@1239|Firmicutes,4HD8F@91061|Bacilli,3F572@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 degV - - - - - - - - - - - DegV MHFCBNDO_01419 543734.LCABL_14430 2.07e-135 384.0 COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli,3F4VH@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Lux Regulon desR - - ko:K02479,ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg MHFCBNDO_01420 543734.LCABL_14440 2.43e-264 724.0 COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli,3F3VR@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 MHFCBNDO_01421 543734.LCABL_14450 1.17e-169 475.0 COG0842@1|root,COG0842@2|Bacteria,1V7QG@1239|Firmicutes,4HFU4@91061|Bacilli,3F5Q7@33958|Lactobacillaceae 91061|Bacilli V ABC-2 type transporter XK27_09830 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 MHFCBNDO_01422 543734.LCABL_14460 1.63e-201 559.0 COG1131@1|root,COG1131@2|Bacteria,1TRM5@1239|Firmicutes,4HFBN@91061|Bacilli,3FC3M@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yvfR - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_01423 543734.LCABL_14470 2.98e-272 749.0 2DKMH@1|root,309XQ@2|Bacteria,1U5WE@1239|Firmicutes,4IFK1@91061|Bacilli,3F6MD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01424 543734.LCABL_14480 1.41e-84 250.0 COG0789@1|root,COG0789@2|Bacteria,1VKCY@1239|Firmicutes,4HSCZ@91061|Bacilli,3F88Z@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 MHFCBNDO_01425 543734.LCABL_14490 1.1e-62 192.0 2EJFD@1|root,33D6D@2|Bacteria,1U38N@1239|Firmicutes,4HRYN@91061|Bacilli,3F8AW@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2568) - - - - - - - - - - - - DUF2568 MHFCBNDO_01426 543734.LCABL_14500 2.93e-143 404.0 2C09S@1|root,30187@2|Bacteria,1U5GF@1239|Firmicutes,4IF7A@91061|Bacilli,3F5VJ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function C-terminus (DUF2399) - - - - - - - - - - - - DUF2399 MHFCBNDO_01427 543734.LCABL_14510 8.42e-156 437.0 COG0454@1|root,COG0456@2|Bacteria,1U91G@1239|Firmicutes,4IJ1J@91061|Bacilli,3F938@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 MHFCBNDO_01428 543734.LCABL_14520 1.23e-57 178.0 COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,4HR7A@91061|Bacilli,3F7DM@33958|Lactobacillaceae 91061|Bacilli L RelB antitoxin - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB MHFCBNDO_01429 1133569.AHYZ01000076_gene68 1.2e-60 187.0 COG3041@1|root,COG3041@2|Bacteria,1TUTW@1239|Firmicutes,4IGG3@91061|Bacilli,3F88F@33958|Lactobacillaceae 91061|Bacilli S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - YafQ_toxin MHFCBNDO_01431 543734.LCABL_14570 0.0 1375.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,3F415@33958|Lactobacillaceae 91061|Bacilli K Tex-like protein N-terminal domain protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF MHFCBNDO_01432 568703.LGG_01253 2.56e-89 266.0 COG1476@1|root,COG1476@2|Bacteria,1V8IM@1239|Firmicutes,4HQD4@91061|Bacilli 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 MHFCBNDO_01434 543734.LCABL_14670 0.0 1021.0 2BW5H@1|root,2ZPYH@2|Bacteria,1V4JH@1239|Firmicutes,4HPU9@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01435 641146.HMPREF9020_01154 9.49e-302 822.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 MHFCBNDO_01436 543734.LCABL_14750 5.31e-143 403.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,3F3P0@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 MHFCBNDO_01437 543734.LCABL_14760 7.1e-111 318.0 COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,3F6NT@33958|Lactobacillaceae 91061|Bacilli T GAF domain-containing protein yebR - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 MHFCBNDO_01438 543734.LCABL_14770 0.0 1038.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,3F47K@33958|Lactobacillaceae 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA MHFCBNDO_01439 543734.LCABL_14780 3.53e-271 744.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,3F4CD@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 MHFCBNDO_01440 543734.LCABL_14790 1.42e-287 786.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,3F3N0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI MHFCBNDO_01441 543734.LCABL_14800 1.24e-148 419.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,3F676@33958|Lactobacillaceae 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N MHFCBNDO_01442 543734.LCABL_14810 0.0 1792.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,3F3RB@33958|Lactobacillaceae 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 MHFCBNDO_01443 543734.LCABL_14820 5.15e-307 837.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,3F498@33958|Lactobacillaceae 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M MHFCBNDO_01444 543734.LCABL_14830 8.07e-148 416.0 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli,3F56K@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 MHFCBNDO_01445 543734.LCABL_14840 1.97e-152 429.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,3F5IM@33958|Lactobacillaceae 91061|Bacilli L DNA repair protein radC - - ko:K03630 - - - - ko00000 - - - RadC MHFCBNDO_01446 543734.LCABL_14850 4.82e-229 632.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F3ZV@33958|Lactobacillaceae 91061|Bacilli D cell shape determining protein MreB mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl MHFCBNDO_01447 543734.LCABL_14860 1.88e-191 533.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,3F3MC@33958|Lactobacillaceae 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC MHFCBNDO_01448 543734.LCABL_14870 8.66e-113 325.0 COG2891@1|root,COG2891@2|Bacteria,1VEV7@1239|Firmicutes,4HPAC@91061|Bacilli,3F6PG@33958|Lactobacillaceae 91061|Bacilli M rod shape-determining protein MreD mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD MHFCBNDO_01449 543734.LCABL_14880 2.69e-148 418.0 COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,4HBTI@91061|Bacilli,3F61V@33958|Lactobacillaceae 91061|Bacilli D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization minC GO:0000910,GO:0003674,GO:0004857,GO:0007049,GO:0007105,GO:0008150,GO:0009987,GO:0022402,GO:0030234,GO:0031333,GO:0032271,GO:0032272,GO:0032506,GO:0043086,GO:0043254,GO:0044087,GO:0044092,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0065009,GO:0098772 - ko:K03610 - - - - ko00000,ko03036,ko04812 - - - MinC_C MHFCBNDO_01450 543734.LCABL_14890 8.63e-182 506.0 COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,4HB2F@91061|Bacilli,3F3U8@33958|Lactobacillaceae 91061|Bacilli D Belongs to the ParA family minD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03609 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA MHFCBNDO_01451 543734.LCABL_14900 4.79e-142 402.0 COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli,3F3VF@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease yecS_2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 MHFCBNDO_01452 543734.LCABL_14910 3.29e-146 412.0 COG1126@1|root,COG1126@2|Bacteria,1UYAZ@1239|Firmicutes,4HE6M@91061|Bacilli,3F4GP@33958|Lactobacillaceae 91061|Bacilli E ABC transporter glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran MHFCBNDO_01453 543734.LCABL_14920 2.32e-193 536.0 COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,4HF14@91061|Bacilli,3F3WC@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein aatB - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 MHFCBNDO_01454 543734.LCABL_14930 0.0 932.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F542@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N MHFCBNDO_01455 1423732.BALS01000025_gene2376 7.11e-60 186.0 29Q7N@1|root,30B6Q@2|Bacteria,1U7MX@1239|Firmicutes,4IHJ5@91061|Bacilli,3F9XF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01456 543734.LCABL_14960 1.61e-101 293.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,3F6K3@33958|Lactobacillaceae 91061|Bacilli K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ MHFCBNDO_01457 543734.LCABL_14970 6.77e-219 604.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,3F3MF@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 MHFCBNDO_01458 568703.LGG_01279 1.6e-68 208.0 COG4839@1|root,COG4839@2|Bacteria 2|Bacteria D cell division protein FtsL ftsL - - - - - - - - - - - DivIC MHFCBNDO_01459 543734.LCABL_14990 0.0 1324.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,3F47N@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase MHFCBNDO_01460 543734.LCABL_15000 1.09e-229 632.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,3F3YP@33958|Lactobacillaceae 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 MHFCBNDO_01461 543734.LCABL_15010 0.0 916.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,3F49W@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M MHFCBNDO_01462 543734.LCABL_15020 9.42e-258 707.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,3F4FW@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 MHFCBNDO_01463 543734.LCABL_15030 5.91e-200 554.0 COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,3F406@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 MHFCBNDO_01464 543734.LCABL_15040 1.44e-311 850.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,3F413@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA MHFCBNDO_01465 543734.LCABL_15050 6.55e-291 795.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,3F4V1@33958|Lactobacillaceae 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin MHFCBNDO_01466 543734.LCABL_15060 5.95e-101 293.0 COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,4HKIC@91061|Bacilli,3F7MQ@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF MHFCBNDO_01467 543734.LCABL_15070 5.58e-60 185.0 COG0762@1|root,COG0762@2|Bacteria,1VEKA@1239|Firmicutes,4HNJR@91061|Bacilli 91061|Bacilli S integral membrane protein ylmG - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT MHFCBNDO_01468 543734.LCABL_15080 1.45e-186 518.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,3F48W@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein ylmH - - - - - - - - - - - S4 MHFCBNDO_01469 543734.LCABL_15090 8.49e-120 349.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HJYN@91061|Bacilli,3FC2J@33958|Lactobacillaceae 91061|Bacilli D DivIVA protein divIVA - - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA MHFCBNDO_01470 543734.LCABL_15110 0.0 1897.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,3F3X4@33958|Lactobacillaceae 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS MHFCBNDO_01471 543734.LCABL_15120 4.62e-48 153.0 COG1278@1|root,COG1278@2|Bacteria,1W688@1239|Firmicutes,4I1Y3@91061|Bacilli,3F81I@33958|Lactobacillaceae 91061|Bacilli K Cold shock protein cspB - - ko:K03704 - - - - ko00000,ko03000 - - - CSD MHFCBNDO_01472 543734.LCABL_15130 5.93e-207 573.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 MHFCBNDO_01473 543734.LCABL_15140 0.0 917.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F4D4@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator ydiC1 - - - - - - - - - - - MFS_1 MHFCBNDO_01474 543734.LCABL_15150 7.29e-270 741.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,4H9Z6@91061|Bacilli,3F5KJ@33958|Lactobacillaceae 91061|Bacilli P Toxic anion resistance protein (TelA) yaaN - - - - - - - - - - - TelA MHFCBNDO_01475 543734.LCABL_15160 8.03e-151 424.0 COG4915@1|root,COG4915@2|Bacteria,1VB0U@1239|Firmicutes,4HMAQ@91061|Bacilli,3F7AZ@33958|Lactobacillaceae 91061|Bacilli S 5-bromo-4-chloroindolyl phosphate hydrolysis protein - - - - - - - - - - - - Halogen_Hydrol MHFCBNDO_01476 543734.LCABL_15170 6.12e-123 350.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,3F53J@33958|Lactobacillaceae 91061|Bacilli L ADP-ribose pyrophosphatase nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX MHFCBNDO_01477 1423732.BALS01000015_gene1677 2.86e-39 132.0 2A67P@1|root,30AP5@2|Bacteria,1U6XT@1239|Firmicutes,4IGS2@91061|Bacilli,3F8PG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01478 543734.LCABL_15190 1.95e-159 447.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,3F4HE@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 MHFCBNDO_01479 543734.LCABL_15200 3.99e-278 760.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,3F3RF@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 MHFCBNDO_01480 543734.LCABL_15210 1.21e-75 226.0 2DHWG@1|root,32U9W@2|Bacteria,1VDSF@1239|Firmicutes,4HP9N@91061|Bacilli,3F7E3@33958|Lactobacillaceae 91061|Bacilli S Putative amino acid metabolism XK27_04120 - - - - - - - - - - - DUF1831 MHFCBNDO_01481 543734.LCABL_15220 0.0 1513.0 COG0178@1|root,COG0178@2|Bacteria,1TR1H@1239|Firmicutes,4H9RE@91061|Bacilli,3F50Y@33958|Lactobacillaceae 91061|Bacilli L ABC transporter uvrA2 - - - - - - - - - - - ABC_tran MHFCBNDO_01482 543734.LCABL_15230 4.09e-304 830.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,3F4N5@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans MHFCBNDO_01484 543734.LCABL_15240 4.69e-159 445.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F3U3@33958|Lactobacillaceae 91061|Bacilli G phosphoglycerate mutase pgm6 - - - - - - - - - - - His_Phos_1 MHFCBNDO_01485 543734.LCABL_15250 3.26e-151 426.0 COG0457@1|root,COG0457@2|Bacteria,1VFGR@1239|Firmicutes,4IBSH@91061|Bacilli,3F4MD@33958|Lactobacillaceae 91061|Bacilli S repeat protein - - - - - - - - - - - - TPR_12,TPR_16,TPR_19,TPR_2,TPR_8 MHFCBNDO_01486 543734.LCABL_15260 0.0 1590.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,3F44X@33958|Lactobacillaceae 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 MHFCBNDO_01487 543734.LCABL_15270 1.65e-311 846.0 COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes,4HD22@91061|Bacilli,3F5HJ@33958|Lactobacillaceae 91061|Bacilli S Sterol carrier protein domain - - - - - - - - - - - - Acetyltransf_9,SCP2_2 MHFCBNDO_01488 543734.LCABL_15280 1.15e-232 639.0 COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,4HBUD@91061|Bacilli,3F5GQ@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat MHFCBNDO_01489 543734.LCABL_15290 0.0 1103.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3TT@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL MHFCBNDO_01490 543734.LCABL_15300 2.02e-43 141.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,3F807@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 MHFCBNDO_01491 543734.LCABL_15310 1.11e-95 279.0 2C389@1|root,2ZQCN@2|Bacteria,1VQPI@1239|Firmicutes,4I0G9@91061|Bacilli,3F79N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01492 543734.LCABL_15320 7.04e-63 192.0 29QQZ@1|root,30BQS@2|Bacteria,1U8HD@1239|Firmicutes,4IIF9@91061|Bacilli,3FAZK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01493 543734.LCABL_15330 4.82e-132 374.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HH0G@91061|Bacilli,3F3YH@33958|Lactobacillaceae 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase MHFCBNDO_01494 1423816.BACQ01000014_gene486 5.13e-112 330.0 29Q2F@1|root,30B13@2|Bacteria,1U7D2@1239|Firmicutes,4IH8M@91061|Bacilli,3F9EB@33958|Lactobacillaceae 91061|Bacilli S E1-E2 ATPase - - - - - - - - - - - - E1-E2_ATPase MHFCBNDO_01495 543734.LCABL_15360 1.42e-267 732.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PQ@91061|Bacilli,3F3JK@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase E1 component pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh MHFCBNDO_01496 543734.LCABL_15370 1.15e-232 640.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HA4H@91061|Bacilli,3F4RV@33958|Lactobacillaceae 91061|Bacilli C Transketolase, C-terminal domain protein pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14590 Transket_pyr,Transketolase_C MHFCBNDO_01497 543734.LCABL_15380 0.0 984.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,3F3RR@33958|Lactobacillaceae 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding MHFCBNDO_01498 543734.LCABL_15390 0.0 894.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,3F426@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase pdhD - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim MHFCBNDO_01499 543734.LCABL_15400 4.32e-202 560.0 COG0039@1|root,COG0039@2|Bacteria,1UFQZ@1239|Firmicutes,4IEWQ@91061|Bacilli,3F4RQ@33958|Lactobacillaceae 91061|Bacilli C L-malate dehydrogenase activity - - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - - MHFCBNDO_01500 543734.LCABL_15410 6.15e-62 189.0 COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli,3F80A@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0223 family yktA - - - - - - - - - - - UPF0223 MHFCBNDO_01501 543734.LCABL_15420 3.56e-189 525.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,3F5BB@33958|Lactobacillaceae 91061|Bacilli G Belongs to the inositol monophosphatase superfamily suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P MHFCBNDO_01502 543734.LCABL_15430 0.0 1198.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,3F3UK@33958|Lactobacillaceae 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 MHFCBNDO_01503 543734.LCABL_15440 1.66e-269 739.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,3F4IK@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE MHFCBNDO_01504 543734.LCABL_15450 0.0 2245.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,3F4U7@33958|Lactobacillaceae 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA MHFCBNDO_01505 543734.LCABL_15460 9.89e-83 244.0 COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli,3F70V@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2129) ylbG - - - - - - - - - - - DUF2129 MHFCBNDO_01506 543734.LCABL_15470 9.93e-130 369.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,3F505@33958|Lactobacillaceae 91061|Bacilli L RNA methyltransferase, RsmD family rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 MHFCBNDO_01507 543734.LCABL_15480 1.79e-112 323.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,3F6YS@33958|Lactobacillaceae 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like MHFCBNDO_01508 543734.LCABL_15490 1.82e-233 644.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,3F4KY@33958|Lactobacillaceae 91061|Bacilli T Belongs to the peptidase S16 family lon - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 MHFCBNDO_01509 543734.LCABL_15500 7.34e-148 417.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,3F7NP@33958|Lactobacillaceae 91061|Bacilli L Competence protein ComEA comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB MHFCBNDO_01510 543734.LCABL_15510 0.0 1432.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,3F3VT@33958|Lactobacillaceae 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B MHFCBNDO_01511 543734.LCABL_15520 2.07e-221 613.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,3F3TP@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta MHFCBNDO_01512 543734.LCABL_15530 1.44e-47 152.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,3F7D8@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p MHFCBNDO_01513 543734.LCABL_15540 5e-57 177.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,3F7DV@33958|Lactobacillaceae 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 MHFCBNDO_01514 1423816.BACQ01000014_gene466 1.34e-62 202.0 29Q46@1|root,30B2W@2|Bacteria,1U7FW@1239|Firmicutes,4IHBY@91061|Bacilli,3F9K7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01515 543734.LCABL_15560 0.0 1100.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3U9@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL MHFCBNDO_01516 543734.LCABL_15570 1.93e-213 590.0 COG0457@1|root,COG0457@2|Bacteria,1W4AR@1239|Firmicutes,4HZIS@91061|Bacilli 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - - MHFCBNDO_01517 543734.LCABL_15580 4.73e-286 781.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,3F3ZP@33958|Lactobacillaceae 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - ko:K02358,ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 MHFCBNDO_01518 1423816.BACQ01000013_gene462 6.59e-90 271.0 COG5434@1|root,COG5434@2|Bacteria,1TQXN@1239|Firmicutes,4HBHT@91061|Bacilli,3F4Y5@33958|Lactobacillaceae 91061|Bacilli M Protein of unknown function (DUF3737) - - - - - - - - - - - - DUF3737 MHFCBNDO_01519 1423732.BALS01000013_gene1548 5.48e-154 434.0 COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HC4I@91061|Bacilli,3F9HM@33958|Lactobacillaceae 91061|Bacilli K Sir2 family - - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 MHFCBNDO_01520 1423732.BALS01000013_gene1549 3.09e-80 238.0 COG0599@1|root,COG0599@2|Bacteria,1V78I@1239|Firmicutes,4HKFY@91061|Bacilli,3F5I2@33958|Lactobacillaceae 91061|Bacilli S Carboxymuconolactone decarboxylase family pcaC - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD MHFCBNDO_01521 1423816.BACQ01000013_gene459 1.02e-76 229.0 COG0789@1|root,COG0789@2|Bacteria,1VB69@1239|Firmicutes,4HN6R@91061|Bacilli,3FC69@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 MHFCBNDO_01522 543734.LCABL_15590 0.0 1033.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yknV - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran MHFCBNDO_01523 543734.LCABL_15600 2.74e-287 788.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,3F40B@33958|Lactobacillaceae 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N MHFCBNDO_01524 543734.LCABL_15610 1.39e-295 807.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,3F41K@33958|Lactobacillaceae 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX MHFCBNDO_01525 543734.LCABL_15620 6.46e-137 387.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,3F44G@33958|Lactobacillaceae 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 MHFCBNDO_01526 543734.LCABL_15630 2.28e-63 193.0 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli,3F6WJ@33958|Lactobacillaceae 91061|Bacilli S mazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG MHFCBNDO_01527 543734.LCABL_15640 3.33e-28 101.0 2AYHS@1|root,31QM8@2|Bacteria,1U8B8@1239|Firmicutes,4II98@91061|Bacilli,3FASP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01528 543734.LCABL_15650 0.0 903.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnPH2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1,SBP_bac_3 MHFCBNDO_01529 543734.LCABL_15660 1.89e-172 481.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran MHFCBNDO_01530 543734.LCABL_15670 0.0 1186.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,3F3MY@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N MHFCBNDO_01531 543734.LCABL_15690 0.0 1234.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F44C@33958|Lactobacillaceae 91061|Bacilli GT Phosphotransferase System fruA - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB MHFCBNDO_01532 543734.LCABL_15700 2.76e-218 602.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,3F3SG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB MHFCBNDO_01533 543734.LCABL_15710 2.78e-170 476.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli,3F3JB@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR MHFCBNDO_01534 543734.LCABL_15720 3.37e-309 842.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,3F4ZA@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 MHFCBNDO_01535 543734.LCABL_15730 0.0 1287.0 COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,3F3WT@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase oatA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - - - - - - - - - - Acyl_transf_3 MHFCBNDO_01536 543734.LCABL_15740 7.76e-233 640.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,3F4F1@33958|Lactobacillaceae 91061|Bacilli J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 MHFCBNDO_01537 543734.LCABL_15750 7.43e-183 509.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,3FC9J@33958|Lactobacillaceae 91061|Bacilli S Enoyl-(Acyl carrier protein) reductase yqjQ - - ko:K07124 - - - - ko00000 - - - adh_short MHFCBNDO_01538 543734.LCABL_15760 2.47e-65 199.0 COG5416@1|root,COG5416@2|Bacteria,1VIG5@1239|Firmicutes,4HP5V@91061|Bacilli,3F7IW@33958|Lactobacillaceae 91061|Bacilli S Lipopolysaccharide assembly protein A domain - - - - - - - - - - - - LapA_dom MHFCBNDO_01539 543734.LCABL_15770 0.0 1645.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3F3RV@33958|Lactobacillaceae 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N MHFCBNDO_01540 543734.LCABL_15780 1.35e-38 128.0 COG0333@1|root,COG0333@2|Bacteria,1VKMZ@1239|Firmicutes,4HR2Q@91061|Bacilli,3F7ZT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p MHFCBNDO_01541 543734.LCABL_15790 6.3e-123 351.0 COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes,4HJXK@91061|Bacilli,3FB3S@33958|Lactobacillaceae 91061|Bacilli K Domain of unknown function (DUF1836) - - - - - - - - - - - - DUF1836 MHFCBNDO_01542 543734.LCABL_15800 0.0 1040.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,3FC24@33958|Lactobacillaceae 91061|Bacilli F 5'-nucleotidase, C-terminal domain ycjM - 3.1.3.5,3.1.3.6,3.1.4.16 ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02370,R02719,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos MHFCBNDO_01543 543734.LCABL_15810 2.47e-184 516.0 2F31P@1|root,33VWT@2|Bacteria,1VWGD@1239|Firmicutes,4HWD9@91061|Bacilli,3F4CP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01544 568703.LGG_01372 8.1e-36 121.0 2BAS8@1|root,3247E@2|Bacteria,1U6V1@1239|Firmicutes,4IGNY@91061|Bacilli,3F8J0@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2929) - - - - - - - - - - - - DUF2929 MHFCBNDO_01545 543734.LCABL_15830 0.0 2145.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,3F4AM@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon MHFCBNDO_01546 543734.LCABL_15840 2.21e-227 626.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,3F4CC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iYO844.BSU29190 PFK MHFCBNDO_01547 543734.LCABL_15850 0.0 1129.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,3F3JU@33958|Lactobacillaceae 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C MHFCBNDO_01548 543734.LCABL_15860 4.31e-95 278.0 COG2707@1|root,COG2707@2|Bacteria,1V7JN@1239|Firmicutes,4IRT9@91061|Bacilli,3FB78@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF441) ytwI - - - - - - - - - - - DUF441 MHFCBNDO_01549 543734.LCABL_15870 5.96e-207 572.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli,3F44W@33958|Lactobacillaceae 91061|Bacilli S S1 domain yitL - - ko:K00243 - - - - ko00000 - - - S1_2 MHFCBNDO_01550 543734.LCABL_15880 9.95e-211 582.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae 91061|Bacilli D recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase MHFCBNDO_01551 543734.LCABL_15890 1.59e-88 259.0 COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,3F7QC@33958|Lactobacillaceae 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ribT - - ko:K02859 - - - - ko00000 - - - Acetyltransf_1 MHFCBNDO_01552 543734.LCABL_15900 2.17e-159 448.0 COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,3FCCZ@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA MHFCBNDO_01553 543734.LCABL_15910 8.74e-139 393.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,3F5RN@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB MHFCBNDO_01554 543734.LCABL_15920 3.15e-175 488.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,3F402@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 MHFCBNDO_01555 543734.LCABL_15930 1.52e-123 353.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,3F4HD@33958|Lactobacillaceae 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt MHFCBNDO_01556 543734.LCABL_15940 1.16e-60 186.0 COG1141@1|root,COG1141@2|Bacteria,1VAC2@1239|Firmicutes,4HKG7@91061|Bacilli,3F7KF@33958|Lactobacillaceae 91061|Bacilli C 4Fe-4S single cluster domain of Ferredoxin I fer GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - ko:K05337 - - - - ko00000 - - - Fer4_13 MHFCBNDO_01557 543734.LCABL_15950 1.19e-230 635.0 COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HJ71@91061|Bacilli,3F45N@33958|Lactobacillaceae 91061|Bacilli S Helix-turn-helix domain - - - - - - - - - - - - HTH_40 MHFCBNDO_01558 543734.LCABL_15960 0.0 912.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3F4PY@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase RecQ recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind MHFCBNDO_01559 543734.LCABL_15970 1.68e-104 306.0 COG1388@1|root,COG1388@2|Bacteria,1VFEU@1239|Firmicutes,4HNW5@91061|Bacilli,3F6WV@33958|Lactobacillaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM MHFCBNDO_01560 543734.LCABL_15980 2.04e-149 421.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,3F3W4@33958|Lactobacillaceae 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin MHFCBNDO_01561 543734.LCABL_15990 4.93e-303 828.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,3F4DQ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 MHFCBNDO_01562 543734.LCABL_16000 7.41e-312 850.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,3F4V0@33958|Lactobacillaceae 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 MHFCBNDO_01563 1423732.BALS01000037_gene108 1.2e-54 171.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,3F6YN@33958|Lactobacillaceae 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding MHFCBNDO_01564 543734.LCABL_16020 1.52e-302 825.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,3F3ND@33958|Lactobacillaceae 91061|Bacilli S Tetratricopeptide repeat protein XK27_05225 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 MHFCBNDO_01565 543734.LCABL_16030 8.71e-200 554.0 COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,4H9UY@91061|Bacilli,3F44R@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 ypjC - - - - - - - - - - - DUF2179,YitT_membrane MHFCBNDO_01566 543734.LCABL_16040 5.31e-284 776.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,3F3VH@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 MHFCBNDO_01567 543734.LCABL_16050 2.95e-110 316.0 2A42J@1|root,30SMC@2|Bacteria,1V54W@1239|Firmicutes,4HGI5@91061|Bacilli,3F3R1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01568 543734.LCABL_16060 0.0 1213.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,3FC7W@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn MHFCBNDO_01569 543734.LCABL_16070 8.15e-242 662.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,3F3SB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt MHFCBNDO_01570 543734.LCABL_16080 1.04e-118 338.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,3F6Y4@33958|Lactobacillaceae 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 MHFCBNDO_01571 543734.LCABL_16090 2.61e-148 417.0 COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,3F578@33958|Lactobacillaceae 91061|Bacilli S protein, hemolysin III hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII MHFCBNDO_01572 543734.LCABL_16100 4.9e-190 529.0 COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli,3F4CW@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family WQ51_01275 - - - - - - - - - - - DegV MHFCBNDO_01573 543734.LCABL_16110 2.41e-196 545.0 COG2755@1|root,COG2755@2|Bacteria,1V1HR@1239|Firmicutes,4HDXS@91061|Bacilli,3F4N0@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase XK27_03630 - - - - - - - - - - - Lipase_GDSL_2 MHFCBNDO_01574 543734.LCABL_16120 3.18e-147 414.0 COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli,3F5K5@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2140) ypmS - - - - - - - - - - - DUF2140 MHFCBNDO_01575 543734.LCABL_16130 1.75e-110 317.0 COG0225@1|root,COG0225@2|Bacteria,1V1MJ@1239|Firmicutes,4HG4U@91061|Bacilli,3FBG0@33958|Lactobacillaceae 91061|Bacilli C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR MHFCBNDO_01576 543734.LCABL_16140 1.03e-54 170.0 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli,3F7ZP@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like MHFCBNDO_01577 543734.LCABL_16150 1.72e-316 865.0 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,3F3SS@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 MHFCBNDO_01578 1423732.BALS01000037_gene93 9.79e-48 155.0 2DMTK@1|root,32TKW@2|Bacteria,1VA3N@1239|Firmicutes,4HMQA@91061|Bacilli,3FC0V@33958|Lactobacillaceae 91061|Bacilli - - XK27_02555 - - - - - - - - - - - - MHFCBNDO_01579 1408311.JNJM01000037_gene2232 5.04e-77 285.0 2C0IE@1|root,2Z7YA@2|Bacteria,1U1MA@1239|Firmicutes,24BCE@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score - - - - - - - - - - - - - MHFCBNDO_01580 585394.RHOM_04430 4.27e-10 72.0 28IAD@1|root,2Z8CZ@2|Bacteria,1V2CR@1239|Firmicutes,24GTF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - MHFCBNDO_01581 1423816.BACQ01000012_gene400 8.1e-76 236.0 29FCS@1|root,302AF@2|Bacteria,1U7WF@1239|Firmicutes,4IHTU@91061|Bacilli,3FA9B@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01582 543734.LCABL_16180 6.99e-242 665.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,3F60U@33958|Lactobacillaceae 91061|Bacilli G Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N MHFCBNDO_01583 543734.LCABL_16190 6.29e-180 502.0 COG1396@1|root,COG1396@2|Bacteria,1TSJ6@1239|Firmicutes,4HC63@91061|Bacilli,3F6KA@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_31 MHFCBNDO_01584 543734.LCABL_16210 1.03e-204 566.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,3F3MI@33958|Lactobacillaceae 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 MHFCBNDO_01585 543734.LCABL_16220 5.87e-178 496.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,3F3JC@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII MHFCBNDO_01586 543734.LCABL_16230 2.69e-188 523.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,3F41U@33958|Lactobacillaceae 91061|Bacilli LU DNA protecting protein DprA dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A MHFCBNDO_01587 543734.LCABL_16250 0.0 1353.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,3F3VS@33958|Lactobacillaceae 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom MHFCBNDO_01588 543734.LCABL_16260 0.0 866.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,3F3WW@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA MHFCBNDO_01589 543734.LCABL_16270 1.66e-216 597.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,3F44K@33958|Lactobacillaceae 91061|Bacilli D Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase MHFCBNDO_01590 543734.LCABL_16280 2.06e-119 341.0 COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,3F4HS@33958|Lactobacillaceae 91061|Bacilli O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome MHFCBNDO_01591 543734.LCABL_16290 0.0 891.0 COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,3F3WB@33958|Lactobacillaceae 91061|Bacilli O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small MHFCBNDO_01592 543734.LCABL_16300 3.11e-218 601.0 COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,4HA4J@91061|Bacilli,3F3KT@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase lacX - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim MHFCBNDO_01593 543734.LCABL_16310 6.92e-141 398.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,3F543@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf MHFCBNDO_01594 543734.LCABL_16320 0.0 1316.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,3F430@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim MHFCBNDO_01595 543734.LCABL_16330 0.0 1582.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,3F3MJ@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV MHFCBNDO_01596 543734.LCABL_16340 0.0 1530.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,4H9RD@91061|Bacilli,3F53K@33958|Lactobacillaceae 91061|Bacilli C Pyruvate formate lyase-like pflB GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like MHFCBNDO_01597 543734.LCABL_16350 2.56e-217 598.0 COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,4HACV@91061|Bacilli,3F472@33958|Lactobacillaceae 91061|Bacilli C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM MHFCBNDO_01598 543734.LCABL_16360 2.6e-232 639.0 COG0583@1|root,COG0583@2|Bacteria,1UYRT@1239|Firmicutes,4IQQ1@91061|Bacilli,3FBIB@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate MHFCBNDO_01599 543734.LCABL_16370 3.24e-220 607.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,3F3PJ@33958|Lactobacillaceae 91061|Bacilli C inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 MHFCBNDO_01600 543734.LCABL_16380 2.86e-267 731.0 COG4974@1|root,COG4974@2|Bacteria,1URNQ@1239|Firmicutes,4HEPI@91061|Bacilli,3FBHV@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family xerS - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase MHFCBNDO_01601 543734.LCABL_16390 7.18e-79 234.0 2E4BT@1|root,33YQ0@2|Bacteria,1VWQW@1239|Firmicutes,4HWWB@91061|Bacilli,3FBRI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01602 543734.LCABL_16400 0.0 1225.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli,3FBRY@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family XK27_05700 - - ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 - - FtsX MHFCBNDO_01603 543734.LCABL_16410 2.68e-176 492.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3F3MG@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein XK27_05695 - - ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 - - ABC_tran MHFCBNDO_01604 543734.LCABL_16420 9.98e-219 604.0 COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,4HFQK@91061|Bacilli,3F5QR@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase-like ATPases kinG - - - - - - - - - - - HATPase_c MHFCBNDO_01605 543734.LCABL_16430 8.31e-158 443.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HIBI@91061|Bacilli,3FC95@33958|Lactobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C MHFCBNDO_01606 543734.LCABL_16440 8.74e-240 662.0 COG0477@1|root,COG0477@2|Bacteria,1UHRM@1239|Firmicutes,4ISTP@91061|Bacilli,3FBXB@33958|Lactobacillaceae 91061|Bacilli EGP Transmembrane secretion effector - - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1 MHFCBNDO_01607 568703.LGG_01431 3.04e-64 198.0 COG0454@1|root,COG0456@2|Bacteria,1UI3A@1239|Firmicutes,4ISBV@91061|Bacilli,3F83Y@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 MHFCBNDO_01608 543734.LCABL_16460 7.34e-86 253.0 COG0454@1|root,COG0456@2|Bacteria,1UVU0@1239|Firmicutes,4IG71@91061|Bacilli,3F7S8@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 MHFCBNDO_01609 543734.LCABL_16470 4.85e-143 404.0 COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HYXD@91061|Bacilli 91061|Bacilli C Nitroreductase family - - - - - - - - - - - - Nitroreductase MHFCBNDO_01610 543734.LCABL_16480 4.92e-258 708.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,3F466@33958|Lactobacillaceae 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 MHFCBNDO_01611 543734.LCABL_16490 2.48e-69 209.0 COG0140@1|root,COG0140@2|Bacteria,1VB6S@1239|Firmicutes,4HKDY@91061|Bacilli,3F7V5@33958|Lactobacillaceae 91061|Bacilli E phosphoribosyl-ATP diphosphatase activity hisE - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH MHFCBNDO_01612 543734.LCABL_16500 1.01e-77 231.0 COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,3F73W@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH MHFCBNDO_01613 543734.LCABL_16510 1.42e-169 474.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli,3F3XV@33958|Lactobacillaceae 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth MHFCBNDO_01614 543734.LCABL_16520 2.66e-158 445.0 COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli,3F5YT@33958|Lactobacillaceae 91061|Bacilli E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth MHFCBNDO_01615 543734.LCABL_16530 5.08e-131 373.0 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HHSP@91061|Bacilli,3FBCG@33958|Lactobacillaceae 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase MHFCBNDO_01616 543734.LCABL_16540 3.22e-135 383.0 COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli,3F4TQ@33958|Lactobacillaceae 91061|Bacilli E imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14130 IGPD MHFCBNDO_01617 543734.LCABL_16550 4.14e-295 807.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,3F40P@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU34910 Histidinol_dh MHFCBNDO_01618 543734.LCABL_16560 2.06e-144 407.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli,3F4WT@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His MHFCBNDO_01619 543734.LCABL_16570 3.15e-277 758.0 COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli,3F4W1@33958|Lactobacillaceae 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His MHFCBNDO_01620 543734.LCABL_16580 6.93e-261 715.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 MHFCBNDO_01621 543734.LCABL_16600 6.76e-129 366.0 COG0494@1|root,COG0494@2|Bacteria,1VXC7@1239|Firmicutes,4HX58@91061|Bacilli,3F45R@33958|Lactobacillaceae 91061|Bacilli L Belongs to the Nudix hydrolase family - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX MHFCBNDO_01622 543734.LCABL_16610 2.95e-205 568.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,3F40W@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family - - - - - - - - - - - - DegV MHFCBNDO_01623 543734.LCABL_16620 0.0 1107.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,3F3PS@33958|Lactobacillaceae 91061|Bacilli K Fibronectin-binding protein FbpA - - - - - - - - - - - DUF814,FbpA MHFCBNDO_01624 543734.LCABL_16630 2.87e-65 199.0 COG1694@1|root,COG1694@2|Bacteria,1VJNA@1239|Firmicutes,4I1AJ@91061|Bacilli 91061|Bacilli S MazG-like family - - - - - - - - - - - - MazG-like MHFCBNDO_01625 543734.LCABL_16640 1.36e-248 685.0 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HAK5@91061|Bacilli,3FCB4@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase system, EIIC pfoS/R - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 MHFCBNDO_01626 543734.LCABL_16650 1.23e-226 624.0 COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,4HBPD@91061|Bacilli,3FCCS@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C MHFCBNDO_01627 543734.LCABL_16660 3.21e-287 788.0 COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,3F7YX@33958|Lactobacillaceae 91061|Bacilli C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) bfmBB - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding MHFCBNDO_01628 543734.LCABL_16670 3.05e-234 644.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,3F4TD@33958|Lactobacillaceae 91061|Bacilli C Transketolase, pyrimidine binding domain bfmBAB - 1.2.4.4 ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU24040 Transket_pyr,Transketolase_C MHFCBNDO_01629 543734.LCABL_16680 9.14e-239 656.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,3F55B@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase E1 component bfmBAA - 1.2.4.4 ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07640 E1_dh MHFCBNDO_01630 543734.LCABL_16690 0.0 900.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,3F5YW@33958|Lactobacillaceae 91061|Bacilli C 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain bfmBC - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim MHFCBNDO_01631 543734.LCABL_16700 1.51e-259 712.0 COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,4H9QV@91061|Bacilli,3F6TG@33958|Lactobacillaceae 91061|Bacilli C Acetokinase family buk - 2.7.2.7 ko:K00929 ko00650,ko01100,map00650,map01100 - R01688 RC00002,RC00043 ko00000,ko00001,ko01000 - - - Acetate_kinase MHFCBNDO_01632 543734.LCABL_16710 8.27e-189 526.0 COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,4HBSK@91061|Bacilli,3F7SC@33958|Lactobacillaceae 91061|Bacilli C Phosphate acetyl/butaryl transferase ptb - 2.3.1.19 ko:K00634 ko00650,ko01100,map00650,map01100 - R01174 RC00004,RC02816 ko00000,ko00001,ko01000 - - - PTA_PTB MHFCBNDO_01633 543734.LCABL_16720 2.06e-145 410.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,3F487@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran MHFCBNDO_01634 543734.LCABL_16730 4.62e-164 459.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,3F47Y@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase MHFCBNDO_01635 543734.LCABL_16740 2.13e-197 548.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,3F4PJ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh MHFCBNDO_01636 543734.LCABL_16750 0.0 2047.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS MHFCBNDO_01637 543734.LCABL_16760 5.32e-267 730.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,3F43R@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase MHFCBNDO_01638 543734.LCABL_16770 4.91e-303 826.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,3F3S3@33958|Lactobacillaceae 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 MHFCBNDO_01639 543734.LCABL_16780 7.64e-229 630.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,3F4BQ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N MHFCBNDO_01640 543734.LCABL_16790 1.64e-299 818.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,3F3UJ@33958|Lactobacillaceae 91061|Bacilli F Permease pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease MHFCBNDO_01641 543734.LCABL_16800 1.05e-125 358.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,3F4SR@33958|Lactobacillaceae 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran MHFCBNDO_01642 543734.LCABL_16810 1.48e-221 610.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,3F3P6@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 MHFCBNDO_01643 543734.LCABL_16820 2.41e-106 306.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,3F66R@33958|Lactobacillaceae 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 MHFCBNDO_01644 543734.LCABL_16830 0.0 1096.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,3F3U6@33958|Lactobacillaceae 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS MHFCBNDO_01645 1423732.BALS01000002_gene1011 8.5e-61 190.0 2BF1V@1|root,328TS@2|Bacteria,1UUT0@1239|Firmicutes,4IHGJ@91061|Bacilli,3F9TN@33958|Lactobacillaceae 91061|Bacilli S Family of unknown function (DUF5322) - - - - - - - - - - - - DUF5322 MHFCBNDO_01646 543734.LCABL_16850 2.37e-91 267.0 COG0328@1|root,COG0328@2|Bacteria,1VH2B@1239|Firmicutes,4HIY9@91061|Bacilli,3F7JC@33958|Lactobacillaceae 91061|Bacilli L Ribonuclease HI rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H,RVT_3 MHFCBNDO_01647 543734.LCABL_16860 2.09e-143 404.0 COG3560@1|root,COG3560@2|Bacteria,1V1CR@1239|Firmicutes,4HD6W@91061|Bacilli,3F576@33958|Lactobacillaceae 91061|Bacilli S Nitroreductase family XK27_02070 - - ko:K07078 - - - - ko00000 - - - Nitroreductase MHFCBNDO_01648 543734.LCABL_16880 0.0 965.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N MHFCBNDO_01649 568703.LGG_01471 5.47e-63 193.0 29PM1@1|root,30AJ7@2|Bacteria,1U6RT@1239|Firmicutes,4IGJ9@91061|Bacilli,3F8DQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01650 543734.LCABL_16900 0.0 951.0 2C9BC@1|root,2ZI2Q@2|Bacteria,1TVHZ@1239|Firmicutes,4I07N@91061|Bacilli 91061|Bacilli S Mga helix-turn-helix domain - - - - - - - - - - - - Mga MHFCBNDO_01651 543734.LCABL_16910 8.72e-52 162.0 COG0695@1|root,COG0695@2|Bacteria,1VEFX@1239|Firmicutes,4HNUX@91061|Bacilli,3F874@33958|Lactobacillaceae 91061|Bacilli O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin MHFCBNDO_01652 543734.LCABL_16920 0.0 1441.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,3F3XG@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN MHFCBNDO_01653 543734.LCABL_16930 8.83e-242 663.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,3F3P1@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm MHFCBNDO_01654 543734.LCABL_16940 3.31e-207 573.0 COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HAZB@91061|Bacilli,3F3VP@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator lysR - - - - - - - - - - - HTH_1,LysR_substrate MHFCBNDO_01655 543734.LCABL_16950 0.0 1271.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F4CX@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N MHFCBNDO_01656 543734.LCABL_16960 1e-248 682.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,3F4UZ@33958|Lactobacillaceae 91061|Bacilli H Lipoate-protein ligase lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C MHFCBNDO_01657 543734.LCABL_16970 8.85e-47 150.0 2CDEF@1|root,30AS2@2|Bacteria,1U71A@1239|Firmicutes,4IGVR@91061|Bacilli,3F8UP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01658 543734.LCABL_16980 2.2e-223 615.0 COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4HAW5@91061|Bacilli,3F4DF@33958|Lactobacillaceae 91061|Bacilli EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C MHFCBNDO_01659 543734.LCABL_16990 2.69e-277 758.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,3F3NZ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 MHFCBNDO_01661 543734.LCABL_17000 7.09e-88 258.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli,3F6VZ@33958|Lactobacillaceae 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA MHFCBNDO_01662 543734.LCABL_17010 6.54e-138 389.0 COG4474@1|root,COG4474@2|Bacteria,1V6SM@1239|Firmicutes,4HJGM@91061|Bacilli,3F4MR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0398 family ypsA - - - - - - - - - - - DUF1273 MHFCBNDO_01663 543734.LCABL_17020 8.49e-156 436.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,3F4DG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU MHFCBNDO_01664 543734.LCABL_17030 0.0 1384.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F424@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein 1A ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 MHFCBNDO_01665 543734.LCABL_17040 5.94e-111 318.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HCDG@91061|Bacilli,3F6BF@33958|Lactobacillaceae 91061|Bacilli F ComE operon protein 2 comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 MHFCBNDO_01666 543734.LCABL_17050 7.61e-148 417.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,3F42U@33958|Lactobacillaceae 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD MHFCBNDO_01667 543734.LCABL_17060 3.19e-146 412.0 COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,3F4FF@33958|Lactobacillaceae 91061|Bacilli L DnaD domain protein dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 MHFCBNDO_01668 543734.LCABL_17070 0.0 896.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,3F4EK@33958|Lactobacillaceae 91061|Bacilli J Asparaginyl-tRNA synthetase asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon MHFCBNDO_01669 543734.LCABL_17080 1.15e-279 764.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 MHFCBNDO_01670 543734.LCABL_17090 3.5e-112 322.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,3F4MM@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria ypmB - - - - - - - - - - - PepSY MHFCBNDO_01671 543734.LCABL_17100 0.0 1761.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,3F4KA@33958|Lactobacillaceae 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII MHFCBNDO_01672 543734.LCABL_17110 0.0 2379.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,3F3Z0@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C MHFCBNDO_01673 543734.LCABL_17120 0.0 2312.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,3F3RS@33958|Lactobacillaceae 91061|Bacilli L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C MHFCBNDO_01675 543734.LCABL_17130 4.56e-216 597.0 COG1577@1|root,COG1577@2|Bacteria,1TT5C@1239|Firmicutes,4HAQQ@91061|Bacilli,3F3TW@33958|Lactobacillaceae 91061|Bacilli I mevalonate kinase mvk - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N MHFCBNDO_01676 543734.LCABL_17140 2.21e-230 635.0 COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli,3F4B5@33958|Lactobacillaceae 91061|Bacilli I diphosphomevalonate decarboxylase mvaD - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N MHFCBNDO_01677 543734.LCABL_17150 2.64e-243 669.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,3F3UY@33958|Lactobacillaceae 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh MHFCBNDO_01678 543734.LCABL_17160 0.0 904.0 COG0144@1|root,COG0144@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli,3F492@33958|Lactobacillaceae 91061|Bacilli J NOL1 NOP2 sun family protein rsmF - - - - - - - - - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI MHFCBNDO_01679 543734.LCABL_17170 1.88e-223 616.0 2EPHD@1|root,33H40@2|Bacteria,1VNCY@1239|Firmicutes,4HYY7@91061|Bacilli,3F495@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - MacB_PCD MHFCBNDO_01680 543734.LCABL_17180 3.71e-183 508.0 2E39Q@1|root,32Y99@2|Bacteria,1VQQ8@1239|Firmicutes,4HRY1@91061|Bacilli,3F4UX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01681 543734.LCABL_17190 2.32e-79 235.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,3F7D5@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein yitW - - - - - - - - - - - DUF1858,FeS_assembly_P MHFCBNDO_01682 543734.LCABL_17200 8.27e-35 119.0 COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli,3F83T@33958|Lactobacillaceae 91061|Bacilli G Belongs to the 4-oxalocrotonate tautomerase family dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase MHFCBNDO_01683 543734.LCABL_17210 1.4e-191 531.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,3F3ZD@33958|Lactobacillaceae 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 MHFCBNDO_01684 543734.LCABL_17220 1.14e-160 451.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,3F4GT@33958|Lactobacillaceae 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK MHFCBNDO_01685 543734.LCABL_17240 9.19e-249 689.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,3F4CF@33958|Lactobacillaceae 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 MHFCBNDO_01686 543734.LCABL_17250 0.0 1169.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,3F3N1@33958|Lactobacillaceae 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 MHFCBNDO_01687 543734.LCABL_17260 0.0 1348.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,3F4G8@33958|Lactobacillaceae 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f MHFCBNDO_01688 568703.LGG_01514 1.48e-219 605.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,3F3T8@33958|Lactobacillaceae 91061|Bacilli J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e MHFCBNDO_01689 543734.LCABL_17280 2.13e-55 174.0 2C8G2@1|root,348DR@2|Bacteria,1VZDC@1239|Firmicutes,4HZ47@91061|Bacilli,3F740@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01690 543734.LCABL_17290 3.64e-70 211.0 2C8G2@1|root,348DR@2|Bacteria,1VZDC@1239|Firmicutes,4HZ47@91061|Bacilli,3F740@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01691 543734.LCABL_17300 2.87e-181 504.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,3F56P@33958|Lactobacillaceae 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N MHFCBNDO_01692 543734.LCABL_17310 2.76e-216 597.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,3F3WQ@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 MHFCBNDO_01693 543734.LCABL_17320 1.38e-84 249.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli,3F7RM@33958|Lactobacillaceae 91061|Bacilli F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 MHFCBNDO_01694 543734.LCABL_17330 6.78e-82 243.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,3F7DC@33958|Lactobacillaceae 91061|Bacilli M Diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSB619.SA_RS07900 DAGK_prokar MHFCBNDO_01695 543734.LCABL_17340 1.03e-106 307.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,3F516@33958|Lactobacillaceae 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 MHFCBNDO_01696 543734.LCABL_17350 8.02e-230 633.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,3F4E7@33958|Lactobacillaceae 91061|Bacilli T phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH MHFCBNDO_01698 543734.LCABL_17360 1.81e-88 261.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,3F6I0@33958|Lactobacillaceae 91061|Bacilli S YqeY-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY MHFCBNDO_01699 543734.LCABL_17370 3.98e-29 104.0 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli,3F81Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 MHFCBNDO_01700 543734.LCABL_17380 3.44e-198 549.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,3F3WK@33958|Lactobacillaceae 91061|Bacilli F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase MHFCBNDO_01701 543734.LCABL_17390 7.94e-207 572.0 COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,4HB4F@91061|Bacilli,3F42I@33958|Lactobacillaceae 91061|Bacilli L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 MHFCBNDO_01702 543734.LCABL_17400 3.1e-216 597.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,3F3PH@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 yitT - - - - - - - - - - - DUF2179,YitT_membrane MHFCBNDO_01703 543734.LCABL_17410 5.11e-106 305.0 COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,4HGWN@91061|Bacilli,3F6H4@33958|Lactobacillaceae 91061|Bacilli O peptide methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR MHFCBNDO_01704 543734.LCABL_17420 0.0 1204.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,3F4PE@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon MHFCBNDO_01705 543734.LCABL_17430 1.32e-310 846.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,3F3M3@33958|Lactobacillaceae 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His MHFCBNDO_01706 543734.LCABL_17440 3.9e-48 155.0 COG0221@1|root,COG0221@2|Bacteria,1VB6Q@1239|Firmicutes,4HKI4@91061|Bacilli,3F81A@33958|Lactobacillaceae 91061|Bacilli C Inorganic pyrophosphatase XK27_04345 - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase MHFCBNDO_01707 543734.LCABL_17450 3.49e-106 312.0 COG0604@1|root,COG0604@2|Bacteria,1VZMF@1239|Firmicutes,4HY0D@91061|Bacilli,3F5Z3@33958|Lactobacillaceae 91061|Bacilli C nadph quinone reductase - - - - - - - - - - - - ADH_zinc_N,ADH_zinc_N_2 MHFCBNDO_01708 543734.LCABL_17480 0.0 947.0 2DV5N@1|root,33U6G@2|Bacteria,1VUTX@1239|Firmicutes,4HVQT@91061|Bacilli,3FBQP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01709 543734.LCABL_17490 2.41e-201 558.0 COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,4HFS1@91061|Bacilli,3F52V@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - - - - - - - - - - ABC_tran MHFCBNDO_01710 543734.LCABL_17500 7.93e-108 310.0 COG0537@1|root,COG0537@2|Bacteria,1V5XZ@1239|Firmicutes,4HHN5@91061|Bacilli,3FCAY@33958|Lactobacillaceae 91061|Bacilli FG adenosine 5'-monophosphoramidase activity - - - - - - - - - - - - HIT MHFCBNDO_01711 543734.LCABL_17510 3.28e-313 853.0 COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,3F4F4@33958|Lactobacillaceae 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3 MHFCBNDO_01712 543734.LCABL_17520 1.35e-150 423.0 COG0546@1|root,COG0546@2|Bacteria,1V3DR@1239|Firmicutes,4HGMU@91061|Bacilli,3F741@33958|Lactobacillaceae 91061|Bacilli J HAD-hyrolase-like - - - - - - - - - - - - HAD_2 MHFCBNDO_01713 543734.LCABL_17530 1.59e-99 289.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,3F6GK@33958|Lactobacillaceae 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase MHFCBNDO_01714 543734.LCABL_17540 0.0 1467.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS MHFCBNDO_01715 1423732.BALS01000048_gene2576 5.49e-58 181.0 2DKTI@1|root,30ARB@2|Bacteria,1U70F@1239|Firmicutes,4IGUR@91061|Bacilli,3F8T9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01716 543734.LCABL_17560 2.57e-169 473.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,3F64Z@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA MHFCBNDO_01717 543734.LCABL_17570 7.07e-222 612.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,3F47Z@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA MHFCBNDO_01718 543734.LCABL_17580 1.42e-112 323.0 2E0MY@1|root,32W75@2|Bacteria,1VFZQ@1239|Firmicutes,4HKWR@91061|Bacilli,3F6FP@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3013) XK27_03960 - - - - - - - - - - - DUF3013 MHFCBNDO_01719 543734.LCABL_17590 5.14e-143 403.0 COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HJ10@91061|Bacilli,3FC7N@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA glycosylase MPG family - GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco MHFCBNDO_01720 543734.LCABL_17600 2.23e-50 159.0 29QBB@1|root,30BAI@2|Bacteria,1U7TK@1239|Firmicutes,4IHR2@91061|Bacilli,3FA5R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01721 543734.LCABL_17610 8.05e-88 258.0 COG5294@1|root,COG5294@2|Bacteria,1W0J9@1239|Firmicutes,4HYK1@91061|Bacilli,3F8AZ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 MHFCBNDO_01722 568703.LGG_01577 1.49e-27 100.0 29QDN@1|root,30BCY@2|Bacteria,1U7XK@1239|Firmicutes,4IHUZ@91061|Bacilli,3FAAQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01723 568703.LGG_01578 1.72e-64 199.0 29PAD@1|root,30A8I@2|Bacteria,1U6BX@1239|Firmicutes,4IG3I@91061|Bacilli,3F7JN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01726 568703.LGG_01582 9.22e-153 439.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,3F4EV@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase mocA - - - - - - - - - - - GFO_IDH_MocA MHFCBNDO_01727 568703.LGG_00349 0.0 931.0 COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli,3F4P6@33958|Lactobacillaceae 91061|Bacilli M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon tagE GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Asp1,Glyco_trans_A_1,Glycos_transf_1 MHFCBNDO_01728 568703.LGG_01587 2.89e-315 865.0 COG0438@1|root,COG0438@2|Bacteria,1UY71@1239|Firmicutes,4HFBM@91061|Bacilli,3FC1Q@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Glycos_transf_1 MHFCBNDO_01730 568703.LGG_01589 1.23e-193 561.0 COG2340@1|root,COG4932@1|root,COG2340@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - 2.4.1.9,3.4.24.40 ko:K01406,ko:K20811 ko00500,ko01503,map00500,map01503 - R04194 RC00077,RC00247 ko00000,ko00001,ko01000,ko01002 - GH68 - CAP,CW_binding_2,SLH MHFCBNDO_01731 543734.LCABL_03600 0.000822 43.9 COG3209@1|root,COG3209@2|Bacteria,1TT3P@1239|Firmicutes,4I28K@91061|Bacilli,3F4YY@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF5011) - - - - - - - - - - - - Big_3,DUF285,Gram_pos_anchor MHFCBNDO_01732 568703.LGG_01591 7.4e-309 880.0 29Q3U@1|root,30B2I@2|Bacteria,1U7FA@1239|Firmicutes,4IHBA@91061|Bacilli,3F9IU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01733 568703.LGG_01592 1.78e-94 353.0 2DQAU@1|root,335PW@2|Bacteria,1VR35@1239|Firmicutes,4HUUM@91061|Bacilli,3F7WX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01734 568703.LGG_01593 7e-123 363.0 29Q4I@1|root,30B38@2|Bacteria,1U7GD@1239|Firmicutes,4IHCJ@91061|Bacilli,3F9M4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01735 543734.LCABL_17680 1.19e-189 526.0 COG3741@1|root,COG3741@2|Bacteria,1V6B3@1239|Firmicutes,4HQ4E@91061|Bacilli,3F6V6@33958|Lactobacillaceae 91061|Bacilli E N-formylglutamate amidohydrolase hutG - 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - FGase MHFCBNDO_01736 543734.LCABL_17690 6.77e-71 213.0 2ED3T@1|root,3370N@2|Bacteria,1VIJK@1239|Firmicutes,4HPGM@91061|Bacilli,3F765@33958|Lactobacillaceae 91061|Bacilli S Staphylococcal protein of unknown function (DUF960) XK27_08430 - - - - - - - - - - - DUF960 MHFCBNDO_01737 543734.LCABL_17700 2.35e-117 335.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HHVB@91061|Bacilli,3F5H1@33958|Lactobacillaceae 91061|Bacilli S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit MHFCBNDO_01738 543734.LCABL_17710 1.7e-123 352.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli,3F4DB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran MHFCBNDO_01739 543734.LCABL_17720 0.0 1481.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,3F42C@33958|Lactobacillaceae 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C MHFCBNDO_01740 1423816.BACQ01000009_gene264 8.85e-76 227.0 29PHG@1|root,30AFM@2|Bacteria,1U6KN@1239|Firmicutes,4IGDE@91061|Bacilli,3F83U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01741 543734.LCABL_17740 4.83e-108 311.0 COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli,3F7EV@33958|Lactobacillaceae 91061|Bacilli S ASCH - - - - - - - - - - - - ASCH MHFCBNDO_01742 1423816.BACQ01000009_gene262 1.32e-33 117.0 2AI13@1|root,318EQ@2|Bacteria,1U7VD@1239|Firmicutes,4IHST@91061|Bacilli,3FA82@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01743 543734.LCABL_17760 0.0 1188.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,3F3Z1@33958|Lactobacillaceae 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C MHFCBNDO_01744 1231336.L248_1955 8.58e-64 211.0 COG1396@1|root,COG1396@2|Bacteria,1V9XM@1239|Firmicutes,4HJUU@91061|Bacilli,3F79A@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K20373 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 MHFCBNDO_01745 1231336.L248_1956 1.43e-176 515.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F4EQ@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran MHFCBNDO_01746 543734.LCABL_17770 2.22e-259 713.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,3F490@33958|Lactobacillaceae 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG MHFCBNDO_01747 543734.LCABL_17780 0.0 1181.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,3F48C@33958|Lactobacillaceae 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 MHFCBNDO_01748 543734.LCABL_17790 3.18e-127 363.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,3F4DY@33958|Lactobacillaceae 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE MHFCBNDO_01749 543734.LCABL_17800 1.6e-246 677.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,3F3ST@33958|Lactobacillaceae 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg MHFCBNDO_01750 543734.LCABL_17810 7.24e-287 782.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,3F4BA@33958|Lactobacillaceae 91061|Bacilli H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM MHFCBNDO_01751 543734.LCABL_17820 1.74e-222 613.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,3F3TG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase MHFCBNDO_01752 543734.LCABL_17830 1.64e-212 587.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,3F3NX@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N MHFCBNDO_01753 543734.LCABL_17840 3.07e-181 509.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,3FB68@33958|Lactobacillaceae 91061|Bacilli P Integral membrane protein TerC family terC - - - - - - - - - - - TerC MHFCBNDO_01754 1423732.BALS01000003_gene941 1.27e-76 229.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,3F6WZ@33958|Lactobacillaceae 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA MHFCBNDO_01755 543734.LCABL_17860 0.0 1570.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,3F3JV@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N MHFCBNDO_01756 543734.LCABL_17870 1.29e-60 187.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,3F7ZK@33958|Lactobacillaceae 91061|Bacilli J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae MHFCBNDO_01757 543734.LCABL_17880 9.63e-61 187.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,3F7E2@33958|Lactobacillaceae 91061|Bacilli K Protein of unknown function (DUF448) ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 MHFCBNDO_01758 543734.LCABL_17890 1.68e-276 759.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,3F3KZ@33958|Lactobacillaceae 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 MHFCBNDO_01759 543734.LCABL_17900 1.33e-110 318.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,3F6GZ@33958|Lactobacillaceae 91061|Bacilli J Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C MHFCBNDO_01760 543734.LCABL_17910 0.0 2863.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,3F4AN@33958|Lactobacillaceae 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon MHFCBNDO_01761 543734.LCABL_17920 0.0 1113.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,3F44A@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit MHFCBNDO_01762 543734.LCABL_17930 3.52e-292 798.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,3F3TM@33958|Lactobacillaceae 91061|Bacilli M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 MHFCBNDO_01763 543734.LCABL_17940 7.66e-179 499.0 COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli,3FC0H@33958|Lactobacillaceae 91061|Bacilli S Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06255 CTP_transf_1 MHFCBNDO_01764 543734.LCABL_17950 4.31e-179 498.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,3F42M@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf MHFCBNDO_01765 543734.LCABL_17960 4.96e-121 346.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,3F4X2@33958|Lactobacillaceae 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF MHFCBNDO_01766 543734.LCABL_17970 5.86e-167 467.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,3F42J@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase MHFCBNDO_01767 543734.LCABL_17980 1.63e-200 556.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,3F459@33958|Lactobacillaceae 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS MHFCBNDO_01768 543734.LCABL_17990 1.18e-182 508.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,3F3M1@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 MHFCBNDO_01769 543734.LCABL_18000 5.38e-61 187.0 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,3F7G2@33958|Lactobacillaceae 91061|Bacilli L GIY-YIG catalytic domain protein yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG MHFCBNDO_01770 543734.LCABL_18010 2.39e-167 468.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,3F4C5@33958|Lactobacillaceae 91061|Bacilli L Methyltransferase small domain yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS MHFCBNDO_01771 543734.LCABL_18020 8.45e-160 447.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,3F4QB@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase MHFCBNDO_01772 543734.LCABL_18030 1.85e-290 798.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid yhdG - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 MHFCBNDO_01773 543734.LCABL_18040 4.28e-181 504.0 COG4420@1|root,COG4420@2|Bacteria,1V46X@1239|Firmicutes,4HI49@91061|Bacilli,3F4FJ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1003) yejC - - - - - - - - - - - DUF1003 MHFCBNDO_01774 543734.LCABL_18050 0.0 1130.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran MHFCBNDO_01775 543734.LCABL_18060 0.0 1139.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran MHFCBNDO_01776 543734.LCABL_18070 1.39e-40 134.0 COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,4HNN9@91061|Bacilli,3FCDQ@33958|Lactobacillaceae 91061|Bacilli S UPF0154 protein yneF - - ko:K09976 - - - - ko00000 - - - UPF0154 MHFCBNDO_01777 543734.LCABL_18080 2.84e-48 154.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,3F87S@33958|Lactobacillaceae 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 MHFCBNDO_01778 568703.LGG_01638 3.28e-28 102.0 29QDP@1|root,30BCZ@2|Bacteria,1U7XM@1239|Firmicutes,4IHV0@91061|Bacilli,3FAAR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01779 543734.LCABL_18100 2e-75 225.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,3F6K4@33958|Lactobacillaceae 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 MHFCBNDO_01780 543734.LCABL_18110 1.76e-185 515.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,3F3NP@33958|Lactobacillaceae 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT MHFCBNDO_01781 543734.LCABL_18120 2.16e-120 343.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,3F74P@33958|Lactobacillaceae 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM MHFCBNDO_01782 543734.LCABL_18140 1.55e-51 162.0 COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4HNX0@91061|Bacilli,3F829@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 MHFCBNDO_01783 543734.LCABL_18150 2.97e-59 182.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 MHFCBNDO_01784 543734.LCABL_18160 2.16e-303 832.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,3F40R@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB MHFCBNDO_01785 543734.LCABL_18170 1.26e-75 226.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli,3F7FG@33958|Lactobacillaceae 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 MHFCBNDO_01786 543734.LCABL_18180 7.91e-70 210.0 2EU16@1|root,33MI8@2|Bacteria,1VPSM@1239|Firmicutes,4HS7T@91061|Bacilli,3F6QA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01787 543734.LCABL_18190 4.3e-231 637.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,3F3YC@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N MHFCBNDO_01788 543734.LCABL_18200 0.0 2097.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,3F478@33958|Lactobacillaceae 91061|Bacilli D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge MHFCBNDO_01789 543734.LCABL_18210 2.8e-161 452.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,3F564@33958|Lactobacillaceae 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm MHFCBNDO_01790 543734.LCABL_18220 0.0 1112.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA1 - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 MHFCBNDO_01791 543734.LCABL_18230 1.16e-193 540.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HA7I@91061|Bacilli,3FCB6@33958|Lactobacillaceae 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component oppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N MHFCBNDO_01792 1423816.BACQ01000007_gene212 3.2e-216 598.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,3FCCU@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease oppB - - ko:K02033,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 MHFCBNDO_01793 543734.LCABL_18260 1.62e-228 629.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,3F4GM@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY MHFCBNDO_01794 543734.LCABL_18270 4.24e-247 678.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3F41T@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY MHFCBNDO_01795 543734.LCABL_18280 3.21e-49 156.0 COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,3F7F4@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding MHFCBNDO_01796 543734.LCABL_18290 5.5e-239 657.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,3F4N9@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis MHFCBNDO_01797 543734.LCABL_18300 0.0 1319.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,3F3JW@33958|Lactobacillaceae 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge MHFCBNDO_01798 543734.LCABL_18310 0.0 1067.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,3F3X0@33958|Lactobacillaceae 91061|Bacilli S DAK2 domain fusion protein YloV yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 MHFCBNDO_01799 543734.LCABL_18320 5.83e-75 224.0 COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,3F72W@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function yloU - - - - - - - - - - - Asp23 MHFCBNDO_01800 543734.LCABL_18330 2.29e-36 122.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli,3F7ZN@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 MHFCBNDO_01801 543734.LCABL_18340 2.62e-166 464.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,3F4N8@33958|Lactobacillaceae 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic MHFCBNDO_01802 543734.LCABL_18350 4.16e-151 425.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,3F4KX@33958|Lactobacillaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim MHFCBNDO_01803 543734.LCABL_18360 5.6e-221 608.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,3F3XH@33958|Lactobacillaceae 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N MHFCBNDO_01804 543734.LCABL_18370 0.0 1176.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase MHFCBNDO_01805 543734.LCABL_18380 5.22e-174 485.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,3F4UI@33958|Lactobacillaceae 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 MHFCBNDO_01806 543734.LCABL_18390 0.0 885.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,3F45F@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB MHFCBNDO_01807 543734.LCABL_18400 1.96e-225 621.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,3F4N7@33958|Lactobacillaceae 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N MHFCBNDO_01808 543734.LCABL_18410 0.0 1586.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,3F3N8@33958|Lactobacillaceae 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII MHFCBNDO_01809 543734.LCABL_18420 8e-275 753.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,3F3XX@33958|Lactobacillaceae 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein MHFCBNDO_01810 543734.LCABL_18430 1.77e-47 152.0 COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4HNHS@91061|Bacilli,3F81N@33958|Lactobacillaceae 91061|Bacilli K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 MHFCBNDO_01811 543734.LCABL_18440 2.52e-148 417.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,3F3X9@33958|Lactobacillaceae 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin MHFCBNDO_01812 1423816.BACQ01000007_gene192 1.65e-117 341.0 COG1752@1|root,COG1752@2|Bacteria,1UXU0@1239|Firmicutes,4IBIE@91061|Bacilli,3F92T@33958|Lactobacillaceae 91061|Bacilli S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin MHFCBNDO_01813 543734.LCABL_18470 2.71e-66 201.0 2DKQQ@1|root,30ACZ@2|Bacteria,1U6H7@1239|Firmicutes,4IG9I@91061|Bacilli,3F7X5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01814 543734.LCABL_18490 0.0 1075.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,3F43U@33958|Lactobacillaceae 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N MHFCBNDO_01815 543734.LCABL_18500 4.19e-96 280.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli,3F71C@33958|Lactobacillaceae 91061|Bacilli K Regulates arginine biosynthesis genes argR2 - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C MHFCBNDO_01816 543734.LCABL_18510 8.09e-197 545.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,3F45T@33958|Lactobacillaceae 91061|Bacilli J Ribosomal RNA large subunit methyltransferase J rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 MHFCBNDO_01817 543734.LCABL_18520 9.01e-190 528.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,3F436@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt MHFCBNDO_01818 543734.LCABL_18530 1.42e-43 142.0 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,3F81K@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S MHFCBNDO_01819 543734.LCABL_18540 1.56e-295 810.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,3F4RE@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 MHFCBNDO_01820 543734.LCABL_18550 4.46e-193 536.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,3F46A@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C MHFCBNDO_01821 543734.LCABL_18560 6.72e-88 258.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,3F7KW@33958|Lactobacillaceae 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB MHFCBNDO_01822 543734.LCABL_18570 9.44e-99 287.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,3F71X@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function WQ51_04310 - - ko:K10947 - - - - ko00000,ko03000 - - - Asp23 MHFCBNDO_01823 543734.LCABL_18580 6.06e-132 374.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F422@33958|Lactobacillaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C MHFCBNDO_01825 543734.LCABL_18590 7.17e-258 706.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,3F4DR@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 MHFCBNDO_01826 543734.LCABL_18600 1.6e-63 194.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,3F6WU@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 MHFCBNDO_01827 543734.LCABL_18610 1.77e-74 223.0 COG2868@1|root,COG2868@2|Bacteria,1VEQ9@1239|Firmicutes,4HNMV@91061|Bacilli,3F839@33958|Lactobacillaceae 91061|Bacilli J Cysteine protease Prp ysxB - - ko:K07584 - - - - ko00000 - - - Peptidase_Prp MHFCBNDO_01828 543734.LCABL_18620 5.83e-67 203.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,3F6WT@33958|Lactobacillaceae 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p MHFCBNDO_01829 1423816.BACQ01000007_gene175 1.17e-16 71.6 29QJP@1|root,30BJ9@2|Bacteria,1U87T@1239|Firmicutes,4II5H@91061|Bacilli,3FANH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01830 1423734.JCM14202_3414 2.12e-40 137.0 292E4@1|root,2ZPYC@2|Bacteria,1W6RP@1239|Firmicutes,4I1K9@91061|Bacilli,3F8JE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01832 543734.LCABL_18670 0.0 1585.0 COG2936@1|root,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4HBA0@91061|Bacilli,3F44E@33958|Lactobacillaceae 91061|Bacilli E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline pepX - 3.4.14.11 ko:K01281 - - - - ko00000,ko01000,ko01002 - - - PepX_C,PepX_N,Peptidase_S15 MHFCBNDO_01833 543734.LCABL_18680 0.0 899.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,3F41A@33958|Lactobacillaceae 91061|Bacilli E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N MHFCBNDO_01834 543734.LCABL_18690 1.32e-80 239.0 COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli,3F7RX@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - MerR_1 MHFCBNDO_01835 543734.LCABL_18700 0.0 1365.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,3F3TV@33958|Lactobacillaceae 91061|Bacilli E Orn/Lys/Arg decarboxylase, C-terminal domain speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.17,4.1.1.18,4.1.1.19 ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 M00133,M00134 R00462,R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C MHFCBNDO_01836 543734.LCABL_18710 5.52e-303 826.0 COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,3F3PU@33958|Lactobacillaceae 91061|Bacilli P aluminum resistance ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - - - - - - - - - - Met_gamma_lyase MHFCBNDO_01837 543734.LCABL_18720 4.43e-222 612.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,3F3XS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT MHFCBNDO_01838 543734.LCABL_18730 3.33e-35 119.0 2C91M@1|root,33E1E@2|Bacteria,1VPEZ@1239|Firmicutes,4HRR2@91061|Bacilli,3F8C0@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3042) WQ51_02665 - - - - - - - - - - - DUF3042 MHFCBNDO_01839 543734.LCABL_18740 1.93e-96 280.0 COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,3F67E@33958|Lactobacillaceae 91061|Bacilli P Rhodanese-like protein yqhL - - - - - - - - - - - Rhodanese MHFCBNDO_01840 543734.LCABL_18750 9.32e-228 627.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,3F4F0@33958|Lactobacillaceae 91061|Bacilli G Glucokinase glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK MHFCBNDO_01841 543734.LCABL_18760 6.79e-55 171.0 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli,3F83I@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF910) yqgQ - - - - - - - - - - - DUF910 MHFCBNDO_01842 543734.LCABL_18770 1.33e-157 442.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,3F3WR@33958|Lactobacillaceae 91061|Bacilli S Peptidase, S54 family gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 MHFCBNDO_01843 543734.LCABL_18780 0.0 1371.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,3F3KH@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbp2b - - ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase MHFCBNDO_01844 543734.LCABL_18810 0.0 1590.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HCR9@91061|Bacilli,3FC7P@33958|Lactobacillaceae 91061|Bacilli S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO MHFCBNDO_01845 543734.LCABL_18820 1.15e-71 215.0 COG4841@1|root,COG4841@2|Bacteria,1VEQE@1239|Firmicutes,4HNU2@91061|Bacilli,3F7SB@33958|Lactobacillaceae 91061|Bacilli S Belongs to the HesB IscA family yneR - - - - - - - - - - - Fe-S_biosyn MHFCBNDO_01846 543734.LCABL_18830 2.04e-149 421.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,3F4DN@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Lux Regulon vraR - - ko:K07694,ko:K11618 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg MHFCBNDO_01847 543734.LCABL_18840 6.31e-230 635.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,3FC2U@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase vraS - 2.7.13.3 ko:K07681,ko:K11617 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 MHFCBNDO_01848 543734.LCABL_18850 3.14e-164 459.0 COG4758@1|root,COG4758@2|Bacteria,1V3D0@1239|Firmicutes,4HDIA@91061|Bacilli,3F5S1@33958|Lactobacillaceae 91061|Bacilli S Cell wall-active antibiotics response 4TMS YvqF yvqF - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 MHFCBNDO_01849 543734.LCABL_18860 1.05e-101 295.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,3F4ZF@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N MHFCBNDO_01850 543734.LCABL_18870 3.43e-148 417.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli,3F3KE@33958|Lactobacillaceae 91061|Bacilli F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK MHFCBNDO_01851 543734.LCABL_18880 7.4e-265 727.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,3F4IG@33958|Lactobacillaceae 91061|Bacilli S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG MHFCBNDO_01852 543734.LCABL_18900 0.0 1576.0 COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,3F3V3@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind MHFCBNDO_01853 543734.LCABL_18910 1.02e-258 708.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,3F4NT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d MHFCBNDO_01854 543734.LCABL_18920 1.2e-87 257.0 COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,3F7FK@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, HxlR family yodB GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HxlR MHFCBNDO_01855 543734.LCABL_18930 3.09e-122 348.0 COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,4HHW0@91061|Bacilli,3F64N@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. XK27_09705 - - ko:K06950 - - - - ko00000 - - - HD MHFCBNDO_01856 543734.LCABL_18940 4.47e-178 496.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,3F3NF@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind MHFCBNDO_01857 543734.LCABL_18950 4.17e-60 186.0 COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,4HNN7@91061|Bacilli,3F81R@33958|Lactobacillaceae 91061|Bacilli C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020 Acylphosphatase MHFCBNDO_01858 543734.LCABL_18960 8.99e-229 631.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli,3F3P3@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP MHFCBNDO_01859 543734.LCABL_18970 0.0 1005.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,3F3NU@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA MHFCBNDO_01860 543734.LCABL_18980 1.01e-157 442.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,3F421@33958|Lactobacillaceae 91061|Bacilli K response regulator csrR - - - - - - - - - - - Response_reg,Trans_reg_C MHFCBNDO_01861 543734.LCABL_18990 0.0 921.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,3F3S8@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 MHFCBNDO_01862 543734.LCABL_19010 3.14e-127 362.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,3F61Z@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized ACR, COG1399 ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 MHFCBNDO_01863 543734.LCABL_19020 2.27e-268 735.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,3F3QC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 MHFCBNDO_01864 543734.LCABL_19030 8.06e-177 492.0 COG0500@1|root,COG0500@2|Bacteria,1UIVS@1239|Firmicutes,4ISTS@91061|Bacilli,3FBXC@33958|Lactobacillaceae 91061|Bacilli Q ubiE/COQ5 methyltransferase family yccK - - - - - - - - - - - Methyltransf_25 MHFCBNDO_01865 543734.LCABL_19040 1.18e-78 234.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,3F7QN@33958|Lactobacillaceae 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS MHFCBNDO_01866 543734.LCABL_19050 3.21e-142 401.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,3F47C@33958|Lactobacillaceae 91061|Bacilli H Hydrolase, HD family yqeK - - - - - - - - - - - HD MHFCBNDO_01867 543734.LCABL_19060 2.72e-157 441.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,3F4D6@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like MHFCBNDO_01868 543734.LCABL_19070 3.95e-65 198.0 COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,3F7EW@33958|Lactobacillaceae 91061|Bacilli J RNA-binding protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY MHFCBNDO_01869 543734.LCABL_19080 3.02e-262 718.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,3F4JU@33958|Lactobacillaceae 91061|Bacilli S Ribosome biogenesis GTPase YqeH yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 MHFCBNDO_01870 543734.LCABL_19090 6.63e-127 360.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,3F46V@33958|Lactobacillaceae 91061|Bacilli S HAD phosphatase, family IIIA yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase MHFCBNDO_01871 543734.LCABL_19100 2.77e-220 607.0 COG0346@1|root,COG0346@2|Bacteria,1VWUR@1239|Firmicutes,4HXTS@91061|Bacilli,3FB66@33958|Lactobacillaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ykcA - - - - - - - - - - - Glyoxalase MHFCBNDO_01872 543734.LCABL_19110 2.74e-243 667.0 COG0346@1|root,COG0346@2|Bacteria,1TP7I@1239|Firmicutes,4H9ND@91061|Bacilli,3F4PB@33958|Lactobacillaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily mhqA_2 - - ko:K15975 - - - - ko00000 - - - Glyoxalase MHFCBNDO_01873 543734.LCABL_19120 4.31e-157 440.0 COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,4HB45@91061|Bacilli,3F6EM@33958|Lactobacillaceae 91061|Bacilli S Dienelactone hydrolase family mhqD - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2,DLH MHFCBNDO_01874 543734.LCABL_19130 7.15e-230 633.0 COG0604@1|root,COG0604@2|Bacteria,1V7QI@1239|Firmicutes,4HJMD@91061|Bacilli,3F69N@33958|Lactobacillaceae 91061|Bacilli C Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 MHFCBNDO_01875 543734.LCABL_19140 8.27e-130 369.0 COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4HE2X@91061|Bacilli,3F5U4@33958|Lactobacillaceae 91061|Bacilli S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox MHFCBNDO_01876 543734.LCABL_19150 1.02e-74 224.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,3F6HZ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 MHFCBNDO_01877 543734.LCABL_19160 1.13e-36 124.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,3F7CQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p MHFCBNDO_01878 543734.LCABL_19170 7.46e-101 293.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,3F4MS@33958|Lactobacillaceae 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N MHFCBNDO_01879 543734.LCABL_19180 9.8e-167 466.0 2DMFR@1|root,32R83@2|Bacteria,1VJJ0@1239|Firmicutes,4HQP8@91061|Bacilli 91061|Bacilli S SseB protein N-terminal domain - - - - - - - - - - - - SseB,SseB_C MHFCBNDO_01880 568703.LGG_01753 5.3e-70 214.0 29Q5P@1|root,30B4K@2|Bacteria,1U7IT@1239|Firmicutes,4IHFJ@91061|Bacilli,3F9S3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01881 543734.LCABL_19200 1.17e-130 371.0 COG0406@1|root,COG0406@2|Bacteria,1V8SE@1239|Firmicutes,4HJCU@91061|Bacilli,3F86H@33958|Lactobacillaceae 91061|Bacilli G Histidine phosphatase superfamily (branch 1) yrgI - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 MHFCBNDO_01882 543734.LCABL_19210 0.0 1326.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,3F3TC@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD MHFCBNDO_01884 568703.LGG_01756 1.02e-180 508.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,3F4JK@33958|Lactobacillaceae 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 MHFCBNDO_01885 543734.LCABL_19240 1.04e-303 830.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,3F5D7@33958|Lactobacillaceae 91061|Bacilli L replication initiation and membrane attachment dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 MHFCBNDO_01886 543734.LCABL_19250 2.06e-103 299.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,3F65S@33958|Lactobacillaceae 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone MHFCBNDO_01887 543734.LCABL_19260 7.76e-130 370.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,3F6WF@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE MHFCBNDO_01888 543734.LCABL_19270 2.52e-203 562.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,3F43E@33958|Lactobacillaceae 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS MHFCBNDO_01889 543734.LCABL_19280 0.0 1715.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,3F3ZA@33958|Lactobacillaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A MHFCBNDO_01890 543734.LCABL_19290 2.55e-155 437.0 COG0670@1|root,COG0670@2|Bacteria,1V9CJ@1239|Firmicutes,4HM3D@91061|Bacilli,3FBMQ@33958|Lactobacillaceae 91061|Bacilli S Inhibitor of apoptosis-promoting Bax1 ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I MHFCBNDO_01891 543734.LCABL_19300 0.0 875.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,3F49J@33958|Lactobacillaceae 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M MHFCBNDO_01892 543734.LCABL_19310 0.0 1424.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,3F441@33958|Lactobacillaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma MHFCBNDO_01893 543734.LCABL_19320 3.17e-149 420.0 COG0073@1|root,COG0073@2|Bacteria,1V7QA@1239|Firmicutes,4HJBD@91061|Bacilli,3FBJ0@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily XK27_10290 - - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind MHFCBNDO_01894 543734.LCABL_19330 5.32e-73 218.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,3F72K@33958|Lactobacillaceae 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin MHFCBNDO_01895 1175629.AJTG01000028_gene188 3.03e-06 50.1 COG5584@1|root,COG5584@2|Bacteria,1TX5V@1239|Firmicutes,4I627@91061|Bacilli,27E5S@186827|Aerococcaceae 91061|Bacilli S Small secreted protein - - - - - - - - - - - - - MHFCBNDO_01896 543734.LCABL_19350 1.35e-155 436.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,3F3QM@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 MHFCBNDO_01897 543734.LCABL_19370 4.51e-189 524.0 COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,3F4GU@33958|Lactobacillaceae 91061|Bacilli M Choline/ethanolamine kinase ytmP - - - - - - - - - - - APH MHFCBNDO_01898 543734.LCABL_19380 1.01e-275 756.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,3F4HH@33958|Lactobacillaceae 91061|Bacilli U ABC transporter ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB MHFCBNDO_01899 543734.LCABL_19390 2.4e-172 481.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,3F444@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_01900 543734.LCABL_19400 1.67e-99 288.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,3F6K5@33958|Lactobacillaceae 91061|Bacilli FG histidine triad hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT MHFCBNDO_01901 543734.LCABL_19410 5.77e-81 240.0 COG4980@1|root,COG4980@2|Bacteria,1VM8M@1239|Firmicutes,4HR25@91061|Bacilli,3F7TT@33958|Lactobacillaceae 91061|Bacilli S YtxH-like protein - - - - - - - - - - - - YtxH MHFCBNDO_01902 543734.LCABL_19420 5.26e-205 568.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,3F45W@33958|Lactobacillaceae 91061|Bacilli M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 MHFCBNDO_01903 543734.LCABL_19430 8.42e-232 638.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,3F4SF@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon MHFCBNDO_01904 543734.LCABL_19440 1.03e-72 218.0 COG3679@1|root,COG3679@2|Bacteria,1V62T@1239|Firmicutes,4IRH3@91061|Bacilli,3FBP8@33958|Lactobacillaceae 91061|Bacilli S Control of competence regulator ComK, YlbF/YmcA - - - - - - - - - - - - Com_YlbF MHFCBNDO_01905 543734.LCABL_19450 0.0 1352.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F49Q@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein pbp2A - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase MHFCBNDO_01906 543734.LCABL_19460 1.3e-198 550.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,3F50K@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 MHFCBNDO_01907 543734.LCABL_19470 3.31e-98 286.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HN5H@91061|Bacilli,3FBR5@33958|Lactobacillaceae 91061|Bacilli K Regulates arginine biosynthesis genes argR1 - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C MHFCBNDO_01908 543734.LCABL_19480 0.0 1107.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,3F4DE@33958|Lactobacillaceae 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d MHFCBNDO_01910 543734.LCABL_19500 1.97e-88 259.0 2A8KV@1|root,30XP9@2|Bacteria,1U6R7@1239|Firmicutes,4IGII@91061|Bacilli,3F8CJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01911 543734.LCABL_19510 1.16e-31 110.0 29QNK@1|root,30BN8@2|Bacteria,1U8CT@1239|Firmicutes,4IIAS@91061|Bacilli,3FAUE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01912 543734.LCABL_19520 3.67e-227 625.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HBFE@91061|Bacilli,3FC4P@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of dihydroorotate to orotate pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.5.2,1.3.98.1 ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh MHFCBNDO_01913 543734.LCABL_19530 0.0 1159.0 COG0584@1|root,COG4781@1|root,COG0584@2|Bacteria,COG4781@2|Bacteria,1UG1C@1239|Firmicutes,4HCPQ@91061|Bacilli,3F3SZ@33958|Lactobacillaceae 91061|Bacilli C phosphodiesterase glpQ4 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,GPDPase_memb MHFCBNDO_01914 543734.LCABL_19540 1.44e-157 442.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HID6@91061|Bacilli,3F5G4@33958|Lactobacillaceae 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K16511 - - - - ko00000 - - - MecA MHFCBNDO_01915 543734.LCABL_19550 1.13e-89 263.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F6HJ@33958|Lactobacillaceae 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC MHFCBNDO_01916 543734.LCABL_19560 3.28e-176 491.0 COG1234@1|root,COG1234@2|Bacteria,1V1TF@1239|Firmicutes,4HFNV@91061|Bacilli,3F4U0@33958|Lactobacillaceae 91061|Bacilli S Metallo-beta-lactamase superfamily yhfI GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - - - - - - - - - - Lactamase_B,Lactamase_B_2 MHFCBNDO_01917 543734.LCABL_19570 7.88e-121 344.0 COG2329@1|root,COG2329@2|Bacteria 2|Bacteria S heme oxygenase (decyclizing) activity traP GO:0005575,GO:0016020 1.14.99.57,6.2.1.3 ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - ABM MHFCBNDO_01918 543734.LCABL_19580 0.0 1228.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli,3F5VK@33958|Lactobacillaceae 91061|Bacilli V ABC transporter (permease) - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX MHFCBNDO_01919 543734.LCABL_19590 1.14e-177 495.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3F5FY@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_01920 543734.LCABL_19600 1.57e-159 447.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli,3F5NZ@33958|Lactobacillaceae 91061|Bacilli K response regulator rrp1 - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C MHFCBNDO_01921 543734.LCABL_19610 4.52e-262 718.0 COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,4HCB6@91061|Bacilli,3FBXD@33958|Lactobacillaceae 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - ko:K19168 - - - - ko00000,ko02048 - - - HATPase_c MHFCBNDO_01922 543734.LCABL_19620 3.11e-141 398.0 COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HGJ9@91061|Bacilli,3F46H@33958|Lactobacillaceae 91061|Bacilli O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM MHFCBNDO_01923 543734.LCABL_19630 0.0 1335.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,3F4IX@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase copB - 3.6.3.3,3.6.3.4,3.6.3.5 ko:K01533,ko:K01534 - - R00086 RC00002 ko00000,ko01000 3.A.3.5,3.A.3.6 - - E1-E2_ATPase,Hydrolase MHFCBNDO_01924 543734.LCABL_19640 1.17e-100 291.0 COG3682@1|root,COG3682@2|Bacteria,1VA7Q@1239|Firmicutes,4HKGF@91061|Bacilli,3F7D0@33958|Lactobacillaceae 91061|Bacilli K Copper transport repressor CopY TcrY copR - - ko:K02171 ko01501,map01501 M00627 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Penicillinase_R MHFCBNDO_01925 641146.HMPREF9020_01154 9.49e-302 822.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 MHFCBNDO_01926 543734.LCABL_19650 1.57e-299 816.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,3F4Z8@33958|Lactobacillaceae 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N MHFCBNDO_01927 543734.LCABL_19660 0.0 998.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,3F4FD@33958|Lactobacillaceae 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS MHFCBNDO_01928 543734.LCABL_19670 1.12e-128 366.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli,3F3UN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N MHFCBNDO_01929 543734.LCABL_19680 1.98e-234 645.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,3F4RT@33958|Lactobacillaceae 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C MHFCBNDO_01930 543734.LCABL_19690 0.0 956.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,3F3U7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran MHFCBNDO_01931 543734.LCABL_19700 0.0 1441.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,3F4IQ@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C MHFCBNDO_01932 543734.LCABL_19710 1.39e-164 460.0 COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,3F48D@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 MHFCBNDO_01933 543734.LCABL_19720 8.48e-55 171.0 COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,3F81F@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU06460 PurS MHFCBNDO_01934 543734.LCABL_19730 1.63e-172 481.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli,3F44Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt MHFCBNDO_01935 543734.LCABL_19740 6.06e-274 748.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,3F3YV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp MHFCBNDO_01936 543734.LCABL_19750 2.66e-102 297.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,3F6P0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC MHFCBNDO_01937 543734.LCABL_19760 3.87e-135 383.0 COG3859@1|root,COG3859@2|Bacteria,1V6YE@1239|Firmicutes,4HIJE@91061|Bacilli,3F738@33958|Lactobacillaceae 91061|Bacilli S Thiamine transporter protein (Thia_YuaJ) thiT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K16789 - - - - ko00000,ko02000 2.A.88.3 - - Thia_YuaJ MHFCBNDO_01938 543734.LCABL_19770 0.0 891.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,3F3ZS@33958|Lactobacillaceae 91061|Bacilli EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family iolT GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K06609 - - - - ko00000,ko02000 2.A.1.1.26 - - Sugar_tr MHFCBNDO_01939 543734.LCABL_19780 0.0 1107.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,3F3MS@33958|Lactobacillaceae 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C MHFCBNDO_01940 1423732.BALS01000007_gene584 1.02e-51 163.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,3F6XQ@33958|Lactobacillaceae 91061|Bacilli G phosphocarrier protein HPR ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr MHFCBNDO_01941 1423816.BACQ01000003_gene57 3.88e-38 127.0 2EI19@1|root,33BSS@2|Bacteria,1VKXC@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - MHFCBNDO_01942 543734.LCABL_19810 0.0 1241.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F3K9@33958|Lactobacillaceae 91061|Bacilli O Belongs to the ClpA ClpB family clpE - - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR MHFCBNDO_01943 543734.LCABL_19820 3.36e-61 188.0 2EBZ8@1|root,335YI@2|Bacteria,1VFRS@1239|Firmicutes,4HNUK@91061|Bacilli,3F70G@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1827) XK27_09445 - - - - - - - - - - - DUF1827 MHFCBNDO_01945 543734.LCABL_19840 0.0 1051.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,3F489@33958|Lactobacillaceae 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C MHFCBNDO_01946 543734.LCABL_19850 1.18e-310 848.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3KG@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain hlyX - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 MHFCBNDO_01947 543734.LCABL_19860 4.17e-262 720.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3F418@33958|Lactobacillaceae 91061|Bacilli S AI-2E family transporter yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport MHFCBNDO_01948 543734.LCABL_19870 1.88e-96 281.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,3F6HQ@33958|Lactobacillaceae 91061|Bacilli S Acetyltransferase (GNAT) domain yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 MHFCBNDO_01949 543734.LCABL_19880 3.88e-123 350.0 29NVN@1|root,30AEE@2|Bacteria,1U6J7@1239|Firmicutes,4IGBR@91061|Bacilli,3F80T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01950 543734.LCABL_19890 1.1e-134 380.0 COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli,3F48S@33958|Lactobacillaceae 91061|Bacilli J Belongs to the UPF0374 family ygaC - - ko:K07586 - - - - ko00000 - - - DUF402 MHFCBNDO_01951 543734.LCABL_19900 7.99e-182 506.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,3F4BY@33958|Lactobacillaceae 91061|Bacilli S Regulatory protein RecX recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX MHFCBNDO_01952 543734.LCABL_19910 0.0 1011.0 COG3711@1|root,COG3711@2|Bacteria 2|Bacteria K transcriptional antiterminator frvR GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K02538,ko:K03483,ko:K09685,ko:K18531 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2 MHFCBNDO_01953 543734.LCABL_19920 1.52e-81 241.0 29Q60@1|root,30B4X@2|Bacteria,1U7J8@1239|Firmicutes,4IHG5@91061|Bacilli,3F9T1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01954 543734.LCABL_19940 0.0 887.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F4GQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr MHFCBNDO_01955 543734.LCABL_19950 1.68e-103 300.0 COG3613@1|root,COG3613@2|Bacteria,1V3SN@1239|Firmicutes,4HH4T@91061|Bacilli,3F6KR@33958|Lactobacillaceae 91061|Bacilli F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr MHFCBNDO_01956 543734.LCABL_19960 2.48e-171 478.0 COG2188@1|root,COG2188@2|Bacteria,1V4DC@1239|Firmicutes,4HIDU@91061|Bacilli,3F6TC@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03489 - - - - ko00000,ko03000 - - - GntR,UTRA MHFCBNDO_01957 543734.LCABL_19970 0.0 1000.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 MHFCBNDO_01958 543734.LCABL_19980 0.0 882.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HDVN@91061|Bacilli,3FC70@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celD - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC MHFCBNDO_01959 543734.LCABL_19990 2.36e-111 320.0 2E5MG@1|root,330CD@2|Bacteria,1VE22@1239|Firmicutes,4IRFH@91061|Bacilli,3FBP1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01960 543734.LCABL_20000 7.89e-66 200.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,3FA2W@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit celC - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA MHFCBNDO_01961 543734.LCABL_20010 6.27e-67 203.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F7XZ@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit ptcB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB MHFCBNDO_01962 543734.LCABL_20020 0.0 1168.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family poxL - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N MHFCBNDO_01963 543734.LCABL_20030 2.6e-279 763.0 COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli,3F425@33958|Lactobacillaceae 91061|Bacilli I Hydroxymethylglutaryl-CoA synthase mvaS - 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 - - - HMG_CoA_synt_C,HMG_CoA_synt_N MHFCBNDO_01964 543734.LCABL_20040 4.66e-267 736.0 COG1257@1|root,COG1257@2|Bacteria,1TPNY@1239|Firmicutes,4HBQ3@91061|Bacilli,3F3YY@33958|Lactobacillaceae 91061|Bacilli C Belongs to the HMG-CoA reductase family mvaA - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red MHFCBNDO_01965 543734.LCABL_20050 6.69e-264 725.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,3F3Q5@33958|Lactobacillaceae 91061|Bacilli I Belongs to the thiolase family atoB - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red,Thiolase_C,Thiolase_N MHFCBNDO_01966 543734.LCABL_20060 7.23e-66 200.0 2B6X8@1|root,31ZX5@2|Bacteria,1U6HZ@1239|Firmicutes,4IGAA@91061|Bacilli,3F7YC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01967 543734.LCABL_20070 5.75e-206 568.0 COG1082@1|root,COG1082@2|Bacteria,1VSC9@1239|Firmicutes,4HUQI@91061|Bacilli,3F4RS@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 MHFCBNDO_01968 543734.LCABL_20080 6.06e-132 374.0 COG1787@1|root,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,4HM6M@91061|Bacilli,3F8C4@33958|Lactobacillaceae 91061|Bacilli V Restriction endonuclease - - - ko:K07448 - - - - ko00000,ko02048 - - - Mrr_cat MHFCBNDO_01969 543734.LCABL_20090 2.25e-201 556.0 COG2017@1|root,COG2017@2|Bacteria 2|Bacteria G converts alpha-aldose to the beta-anomer - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim MHFCBNDO_01970 543734.LCABL_20100 3.11e-271 742.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 MHFCBNDO_01971 543734.LCABL_20110 4.33e-132 375.0 COG4684@1|root,COG4684@2|Bacteria,1VB4T@1239|Firmicutes,4HMUC@91061|Bacilli,3F497@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt MHFCBNDO_01973 543734.LCABL_20130 4e-105 303.0 COG0454@1|root,COG0456@2|Bacteria,1VEF8@1239|Firmicutes 1239|Firmicutes K Acetyltransferase GNAT Family - - - - - - - - - - - - Acetyltransf_1 MHFCBNDO_01974 543734.LCABL_20140 1.65e-111 319.0 COG3091@1|root,COG3091@2|Bacteria,1V6NU@1239|Firmicutes,4HIHY@91061|Bacilli,3F703@33958|Lactobacillaceae 91061|Bacilli S Belongs to the SprT family ydcK - - ko:K03095 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT MHFCBNDO_01975 543734.LCABL_20150 3.35e-167 468.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,3F3NW@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein XK27_08845 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran MHFCBNDO_01976 543734.LCABL_20160 4.02e-188 525.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,3F40J@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family XK27_08840 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 MHFCBNDO_01977 568703.LGG_01853 4.1e-197 551.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F462@33958|Lactobacillaceae 91061|Bacilli S ABC transporter XK27_08835 - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind MHFCBNDO_01979 543734.LCABL_20210 2.77e-94 275.0 2E7AN@1|root,331U3@2|Bacteria,1VFU9@1239|Firmicutes,4HY33@91061|Bacilli,3FBB1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01980 543734.LCABL_20220 0.0 1674.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase MHFCBNDO_01981 543734.LCABL_20230 6.59e-276 754.0 COG1680@1|root,COG1680@2|Bacteria,1V0GX@1239|Firmicutes,4HCXH@91061|Bacilli,3F4TH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase MHFCBNDO_01982 543734.LCABL_20240 2.51e-195 541.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,3F43Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase MHFCBNDO_01983 543734.LCABL_20250 1.57e-280 767.0 COG1680@1|root,COG1680@2|Bacteria,1V0GX@1239|Firmicutes,4HCXH@91061|Bacilli,3F4TH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase MHFCBNDO_01984 543734.LCABL_20260 0.0 951.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase MHFCBNDO_01985 543734.LCABL_20270 1.62e-161 452.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,3F4D0@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein yvoA_2 - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA MHFCBNDO_01986 543734.LCABL_20280 8.7e-279 761.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,3F40F@33958|Lactobacillaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 MHFCBNDO_01987 543734.LCABL_20290 1.13e-177 496.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,3F4SE@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer MHFCBNDO_01988 543734.LCABL_20300 0.0 1362.0 COG1506@1|root,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,3F59I@33958|Lactobacillaceae 91061|Bacilli E Prolyl oligopeptidase family yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 MHFCBNDO_01991 543734.LCABL_20330 2.96e-203 561.0 COG1409@1|root,COG1409@2|Bacteria,1VHY9@1239|Firmicutes,4HPAR@91061|Bacilli,3F3SW@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos MHFCBNDO_01992 543734.LCABL_20340 0.0 924.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,3F4WU@33958|Lactobacillaceae 91061|Bacilli U amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 MHFCBNDO_01993 543734.LCABL_20350 0.0 1444.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F44P@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD MHFCBNDO_01994 543734.LCABL_20360 1.71e-87 256.0 29P63@1|root,30A48@2|Bacteria,1U666@1239|Firmicutes,4IFWC@91061|Bacilli,3F75Z@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01995 543734.LCABL_20370 6.13e-100 289.0 29PS8@1|root,30AQG@2|Bacteria,1U6ZG@1239|Firmicutes,4IGTR@91061|Bacilli,3F8RT@33958|Lactobacillaceae 91061|Bacilli S function, without similarity to other proteins - - - - - - - - - - - - - MHFCBNDO_01996 543734.LCABL_20380 0.0 871.0 COG2211@1|root,COG2211@2|Bacteria,1TS1S@1239|Firmicutes 1239|Firmicutes G MFS/sugar transport protein - - - - - - - - - - - - MFS_2 MHFCBNDO_01997 543734.LCABL_20390 3.08e-291 793.0 COG3669@1|root,COG3669@2|Bacteria,1UYIM@1239|Firmicutes,4HJ46@91061|Bacilli,3F5S7@33958|Lactobacillaceae 91061|Bacilli G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos MHFCBNDO_01998 543734.LCABL_20400 8.15e-77 228.0 29MVS@1|root,308TH@2|Bacteria,1U8JK@1239|Firmicutes,4IIHJ@91061|Bacilli,3FB21@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_01999 543734.LCABL_20410 0.0 1104.0 COG1274@1|root,COG1274@2|Bacteria,1UIM9@1239|Firmicutes,4HED4@91061|Bacilli,3FBXE@33958|Lactobacillaceae 91061|Bacilli C Phosphoenolpyruvate carboxykinase pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP MHFCBNDO_02000 568703.LGG_01877 6.28e-25 93.6 2BP56@1|root,32HW1@2|Bacteria,1U802@1239|Firmicutes,4IHXF@91061|Bacilli,3FADE@33958|Lactobacillaceae 91061|Bacilli S Virus attachment protein p12 family - - - - - - - - - - - - P12 MHFCBNDO_02001 543734.LCABL_20430 0.0 1353.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,3F553@33958|Lactobacillaceae 91061|Bacilli P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - iSB619.SA_RS13395 FeoB_C,FeoB_N,Gate MHFCBNDO_02002 1423816.BACQ01000001_gene6 4.14e-91 269.0 COG1918@1|root,COG1918@2|Bacteria,1VFH1@1239|Firmicutes,4HMT6@91061|Bacilli,3FBMK@33958|Lactobacillaceae 91061|Bacilli P FeoA - - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA MHFCBNDO_02003 543734.LCABL_20460 4.77e-167 468.0 COG2755@1|root,COG2755@2|Bacteria,1UI5G@1239|Firmicutes,4ISEF@91061|Bacilli,3F6R2@33958|Lactobacillaceae 91061|Bacilli E lipolytic protein G-D-S-L family - - - - - - - - - - - - - MHFCBNDO_02006 543734.LCABL_20490 2.51e-150 422.0 COG2910@1|root,COG2910@2|Bacteria,1TZ3T@1239|Firmicutes,4HVUN@91061|Bacilli,3F5K7@33958|Lactobacillaceae 91061|Bacilli S NAD(P)H-binding - - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 MHFCBNDO_02007 1423732.BALS01000053_gene2773 3.31e-78 236.0 29Q3J@1|root,30B27@2|Bacteria,1U7EP@1239|Firmicutes,4IHAJ@91061|Bacilli,3F9HJ@33958|Lactobacillaceae 91061|Bacilli S MucBP domain - - - - - - - - - - - - MucBP MHFCBNDO_02008 543734.LCABL_20510 9.73e-109 314.0 29PA5@1|root,30A8A@2|Bacteria,1U6BM@1239|Firmicutes,4IG39@91061|Bacilli,3F7J0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02011 568703.LGG_00307 5.19e-90 263.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - MHFCBNDO_02014 543734.LCABL_20590 1.81e-292 800.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,3F3M6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b MHFCBNDO_02015 543734.LCABL_20600 0.0 1038.0 COG3711@1|root,COG3711@2|Bacteria,1VVKT@1239|Firmicutes,4HWA8@91061|Bacilli,3F5TE@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - Mga MHFCBNDO_02016 543734.LCABL_20610 0.0 1017.0 COG3711@1|root,COG3711@2|Bacteria,1UVBC@1239|Firmicutes,4I2VB@91061|Bacilli,3F5V6@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - Mga MHFCBNDO_02017 543734.LCABL_20620 0.0 921.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,3F4BG@33958|Lactobacillaceae 91061|Bacilli E amino acid lysP - - ko:K03293,ko:K11733 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.2 - - AA_permease MHFCBNDO_02019 543734.LCABL_20640 2.4e-169 473.0 COG3527@1|root,COG3527@2|Bacteria,1V4AH@1239|Firmicutes,4HJ98@91061|Bacilli,3FCCX@33958|Lactobacillaceae 91061|Bacilli Q Alpha-acetolactate decarboxylase budA - 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy MHFCBNDO_02020 543734.LCABL_20650 0.0 1098.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli,3FCE6@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family alsS - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N MHFCBNDO_02021 543734.LCABL_20660 4.81e-127 361.0 29V6R@1|root,30GKF@2|Bacteria,1UG8K@1239|Firmicutes,4IF4K@91061|Bacilli,3F5MB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02022 543734.LCABL_20670 2.94e-128 363.0 COG1670@1|root,COG1670@2|Bacteria,1V49W@1239|Firmicutes,4HHAP@91061|Bacilli,3F5A6@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain yjcK - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 MHFCBNDO_02023 543734.LCABL_20680 3.08e-242 666.0 COG4072@1|root,COG4072@2|Bacteria 2|Bacteria S Protein of unknown function C-terminal (DUF3324) - - - - - - - - - - - - DUF3324,DUF916 MHFCBNDO_02024 568703.LGG_01903 8.02e-114 328.0 2BIND@1|root,32CVF@2|Bacteria,1U7HI@1239|Firmicutes,4IHE6@91061|Bacilli,3F9PY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02025 1423732.BALS01000021_gene323 1.43e-25 94.7 COG0267@1|root,COG0267@2|Bacteria,1VGZK@1239|Firmicutes,4HSMA@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 MHFCBNDO_02026 543734.LCABL_20710 6.98e-149 418.0 COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,3F6BJ@33958|Lactobacillaceae 91061|Bacilli C Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodA GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005575,GO:0005576,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N MHFCBNDO_02027 543734.LCABL_20720 2.25e-201 558.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3F46Z@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 MHFCBNDO_02028 543734.LCABL_20730 4.2e-200 553.0 COG0657@1|root,COG0657@2|Bacteria,1VEC5@1239|Firmicutes,4HKY6@91061|Bacilli,3F50A@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 MHFCBNDO_02029 1423816.BACQ01000046_gene1709 4.96e-35 125.0 2AIC8@1|root,318TE@2|Bacteria,1U7KZ@1239|Firmicutes,4IHI2@91061|Bacilli,3F9W0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02030 543734.LCABL_20750 7.43e-97 281.0 2EIVY@1|root,33CM8@2|Bacteria,1VKJ5@1239|Firmicutes,4HRQ2@91061|Bacilli,3F7QM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02031 543734.LCABL_20760 8.1e-199 551.0 COG1767@1|root,COG1767@2|Bacteria,1TQGQ@1239|Firmicutes,4HGCS@91061|Bacilli,3F4SU@33958|Lactobacillaceae 91061|Bacilli H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase citG - 2.4.2.52 ko:K05966 ko02020,map02020 - R09675 RC00049,RC00063 ko00000,ko00001,ko01000 - - - CitG MHFCBNDO_02032 543734.LCABL_20780 4.14e-163 456.0 COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,4HATG@91061|Bacilli,3F532@33958|Lactobacillaceae 91061|Bacilli K FCD citR - - - - - - - - - - - FCD,GntR MHFCBNDO_02033 543734.LCABL_20790 0.0 927.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,4HBJ1@91061|Bacilli,3F58W@33958|Lactobacillaceae 91061|Bacilli C Conserved carboxylase domain oadA - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - HMGL-like,PYC_OADA MHFCBNDO_02034 543734.LCABL_20800 4.61e-120 343.0 COG3697@1|root,COG3697@2|Bacteria,1VB3E@1239|Firmicutes,4HMZ5@91061|Bacilli,3F74S@33958|Lactobacillaceae 91061|Bacilli HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase citX - 2.7.7.61 ko:K05964 ko02020,map02020 - R10706 - ko00000,ko00001,ko01000 - - - CitX MHFCBNDO_02035 543734.LCABL_20810 0.0 992.0 COG3051@1|root,COG3051@2|Bacteria,1TPN3@1239|Firmicutes,4HAE1@91061|Bacilli,3F4EA@33958|Lactobacillaceae 91061|Bacilli H Citrate (pro-3S)-lyase alpha chain citF - 2.8.3.10 ko:K01643 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - CitF MHFCBNDO_02036 543734.LCABL_20820 7.46e-201 557.0 COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,4HD40@91061|Bacilli,3F47Q@33958|Lactobacillaceae 91061|Bacilli G Belongs to the HpcH HpaI aldolase family citE - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI MHFCBNDO_02037 543734.LCABL_20830 3.41e-65 198.0 COG3052@1|root,COG3052@2|Bacteria,1VEZZ@1239|Firmicutes,4HNXD@91061|Bacilli,3F7FR@33958|Lactobacillaceae 91061|Bacilli C Covalent carrier of the coenzyme of citrate lyase citD - - ko:K01646 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001 - - - ACP MHFCBNDO_02038 543734.LCABL_20840 2.88e-226 625.0 COG3053@1|root,COG3053@2|Bacteria,1TSGQ@1239|Firmicutes,4HC6Q@91061|Bacilli,3F4H7@33958|Lactobacillaceae 91061|Bacilli H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase citC - 6.2.1.22 ko:K01910 ko02020,map02020 - R04449 RC00012,RC00039 ko00000,ko00001,ko01000 - - - Acetyltransf_10,Citrate_ly_lig MHFCBNDO_02039 1423747.BAMJ01000008_gene716 3.26e-07 48.1 29PZT@1|root,30AY8@2|Bacteria,1U79B@1239|Firmicutes,4IH46@91061|Bacilli,3F95A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02040 543734.LCABL_20860 1.13e-250 690.0 COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,4HEF4@91061|Bacilli,3F61X@33958|Lactobacillaceae 91061|Bacilli C Na+-transporting oxaloacetate decarboxylase beta subunit oadB - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta MHFCBNDO_02041 543734.LCABL_20870 1.76e-59 186.0 COG0511@1|root,COG0511@2|Bacteria,1VW7S@1239|Firmicutes,4HJSW@91061|Bacilli,3F7V3@33958|Lactobacillaceae 91061|Bacilli I Biotin-requiring enzyme oadG - - - - - - - - - - - Biotin_lipoyl MHFCBNDO_02042 543734.LCABL_20880 2.14e-69 209.0 2EDVU@1|root,337QZ@2|Bacteria,1W0WF@1239|Firmicutes,4HZEA@91061|Bacilli,3F8EE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02043 543734.LCABL_20890 4.1e-307 839.0 COG2851@1|root,COG2851@2|Bacteria,1TQQH@1239|Firmicutes,4HAGT@91061|Bacilli,3F5EB@33958|Lactobacillaceae 91061|Bacilli C Citrate transporter citM - - ko:K03300 - - - - ko00000 2.A.11 - - CitMHS MHFCBNDO_02044 543734.LCABL_20900 3.61e-55 172.0 2ENWC@1|root,33GHC@2|Bacteria,1VPIM@1239|Firmicutes,4HRIM@91061|Bacilli,3F826@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02045 543734.LCABL_20910 4.44e-134 379.0 COG1859@1|root,COG1859@2|Bacteria,1V49Y@1239|Firmicutes,4HHHZ@91061|Bacilli,3FBCQ@33958|Lactobacillaceae 91061|Bacilli J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase kptA - - ko:K07559 - - - - ko00000,ko01000,ko03016 - - - PTS_2-RNA MHFCBNDO_02046 543734.LCABL_20920 2.7e-57 181.0 COG0454@1|root,COG0456@2|Bacteria,1V6S5@1239|Firmicutes,4HJJY@91061|Bacilli,3F6HM@33958|Lactobacillaceae 91061|Bacilli K GNAT family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 MHFCBNDO_02047 543734.LCABL_20930 4.49e-136 386.0 COG2085@1|root,COG2085@2|Bacteria,1V35D@1239|Firmicutes,4HFSW@91061|Bacilli,3F5EP@33958|Lactobacillaceae 91061|Bacilli S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored MHFCBNDO_02048 543734.LCABL_20940 1.13e-75 226.0 COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,4HKBS@91061|Bacilli,3F70B@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family padR - - ko:K10947 - - - - ko00000,ko03000 - - - PadR MHFCBNDO_02049 543734.LCABL_20950 1.49e-189 527.0 COG4858@1|root,COG4858@2|Bacteria,1V9IF@1239|Firmicutes,4HKB8@91061|Bacilli,3F6UB@33958|Lactobacillaceae 91061|Bacilli - - ORF00048 - - - - - - - - - - - DUF1129 MHFCBNDO_02050 543734.LCABL_20960 2.58e-176 491.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,3F4IY@33958|Lactobacillaceae 91061|Bacilli C nitroreductase nfrA - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase MHFCBNDO_02051 748671.LCRIS_00536 3.34e-215 594.0 COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,4HC34@91061|Bacilli,3F4JT@33958|Lactobacillaceae 91061|Bacilli V ABC transporter ybhF_1 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 MHFCBNDO_02052 748671.LCRIS_00537 0.0 1008.0 COG3559@1|root,COG3559@2|Bacteria,1TPIG@1239|Firmicutes,4H9SK@91061|Bacilli,3F4PV@33958|Lactobacillaceae 91061|Bacilli M Exporter of polyketide antibiotics - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - MHFCBNDO_02053 543734.LCABL_20990 1.63e-146 413.0 COG1309@1|root,COG1309@2|Bacteria,1VG1F@1239|Firmicutes,4HPER@91061|Bacilli,3F6KD@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_N MHFCBNDO_02054 543734.LCABL_21000 0.0 890.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 MHFCBNDO_02055 543734.LCABL_21010 1.65e-160 451.0 COG0730@1|root,COG0730@2|Bacteria,1V75K@1239|Firmicutes,4HEE8@91061|Bacilli,3F6BU@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE MHFCBNDO_02056 543734.LCABL_21020 4.41e-201 562.0 COG1476@1|root,COG1476@2|Bacteria,1V7TA@1239|Firmicutes,4HWM9@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 MHFCBNDO_02057 543734.LCABL_21030 1.85e-206 570.0 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 MHFCBNDO_02058 543734.LCABL_21040 2.73e-80 238.0 COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,4HPK4@91061|Bacilli,3F6GC@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, GntR family lexA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR MHFCBNDO_02059 543734.LCABL_21050 1.6e-161 453.0 COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HC2V@91061|Bacilli,3FC3Q@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities yhcG - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_02060 525318.HMPREF0497_0206 1.32e-15 81.6 29NT4@1|root,309R6@2|Bacteria,1U5IX@1239|Firmicutes,4HZ1H@91061|Bacilli,3F624@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02061 1158607.UAU_01174 3.8e-176 508.0 2EYF6@1|root,33RP4@2|Bacteria,1VSYT@1239|Firmicutes,4HVCU@91061|Bacilli,4B49Z@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02062 1158607.UAU_01175 1.5e-112 329.0 COG1136@1|root,COG1136@2|Bacteria,1VU5E@1239|Firmicutes,4HV26@91061|Bacilli,4B2U2@81852|Enterococcaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_02063 543734.LCABL_21070 1.01e-122 350.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,3F6YW@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain ydaF GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017198,GO:0018193,GO:0018209,GO:0019538,GO:0030920,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1990189 - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 MHFCBNDO_02064 543734.LCABL_21080 7.79e-203 562.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4HUP0@91061|Bacilli 91061|Bacilli P Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY MHFCBNDO_02065 543734.LCABL_21090 2.29e-253 696.0 COG0444@1|root,COG0444@2|Bacteria,1VRIF@1239|Firmicutes,4HV11@91061|Bacilli 91061|Bacilli P Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY MHFCBNDO_02067 543734.LCABL_21110 3.78e-223 616.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N MHFCBNDO_02068 543734.LCABL_21120 5.97e-215 595.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HU8D@91061|Bacilli 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 MHFCBNDO_02069 543734.LCABL_21130 0.0 1069.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HTMF@91061|Bacilli 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 MHFCBNDO_02070 543734.LCABL_21140 1.98e-163 457.0 COG0693@1|root,COG0693@2|Bacteria,1UG8E@1239|Firmicutes,4HCBM@91061|Bacilli,3F4SD@33958|Lactobacillaceae 91061|Bacilli S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI MHFCBNDO_02071 543734.LCABL_21150 2.12e-70 212.0 COG0640@1|root,COG0640@2|Bacteria,1V6Z2@1239|Firmicutes,4HKFB@91061|Bacilli,3F7CV@33958|Lactobacillaceae 91061|Bacilli K Transcriptional - - - - - - - - - - - - HTH_5 MHFCBNDO_02072 543734.LCABL_21160 8.8e-48 153.0 28QAQ@1|root,2ZCTB@2|Bacteria,1W6HR@1239|Firmicutes,4I0FP@91061|Bacilli,3F7NS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02073 543734.LCABL_21170 0.0 933.0 COG1132@1|root,COG1132@2|Bacteria,1UVV5@1239|Firmicutes,4I2V1@91061|Bacilli,3F9E9@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran MHFCBNDO_02074 543734.LCABL_21180 0.0 993.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F4HU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06147,ko:K06148,ko:K11085,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran MHFCBNDO_02076 543734.LCABL_21200 3.24e-89 261.0 2F916@1|root,309SE@2|Bacteria,1U5KS@1239|Firmicutes,4IFBR@91061|Bacilli,3F65Y@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn MHFCBNDO_02077 1423816.BACQ01000047_gene1752 3.05e-19 86.7 2DQV2@1|root,338VR@2|Bacteria,1VG1G@1239|Firmicutes,4HQEQ@91061|Bacilli,3F9IH@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase enzyme family - - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH MHFCBNDO_02078 568703.LGG_01953 4.56e-298 869.0 COG1388@1|root,COG1388@2|Bacteria,1VQJH@1239|Firmicutes,4HSU2@91061|Bacilli,3F4H3@33958|Lactobacillaceae 91061|Bacilli M LysM domain - - - - - - - - - - - - LysM MHFCBNDO_02079 568703.LGG_01953 5.19e-67 227.0 COG1388@1|root,COG1388@2|Bacteria,1VQJH@1239|Firmicutes,4HSU2@91061|Bacilli,3F4H3@33958|Lactobacillaceae 91061|Bacilli M LysM domain - - - - - - - - - - - - LysM MHFCBNDO_02080 543734.LCABL_21230 1.6e-171 479.0 COG5549@1|root,COG5549@2|Bacteria,1V6X9@1239|Firmicutes,4HK8S@91061|Bacilli,3F6QI@33958|Lactobacillaceae 91061|Bacilli O Zinc-dependent metalloprotease zmp3 - - - - - - - - - - - Peptidase_M10 MHFCBNDO_02081 641146.HMPREF9020_01154 9.49e-302 822.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 MHFCBNDO_02082 543734.LCABL_21250 4.92e-167 468.0 COG1349@1|root,COG1349@2|Bacteria,1UYQX@1239|Firmicutes,4HMB5@91061|Bacilli,3F6Z8@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR MHFCBNDO_02084 543734.LCABL_21270 3.03e-65 199.0 2DCPK@1|root,2ZEV0@2|Bacteria,1TVRG@1239|Firmicutes,4I3X9@91061|Bacilli,3FA25@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain lciIC - - - - - - - - - - - HTH_3 MHFCBNDO_02085 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_02086 290512.Paes_2314 6.12e-110 330.0 COG0270@1|root,COG0270@2|Bacteria,1FF7V@1090|Chlorobi 1090|Chlorobi H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase MHFCBNDO_02087 1123508.JH636442_gene4316 9.03e-11 70.9 COG1106@1|root,COG1106@2|Bacteria 2|Bacteria S AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K06926 - - - - ko00000 - - - AAA_15,AAA_21,AAA_23 MHFCBNDO_02088 568703.LGG_00464 9.37e-227 624.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_02089 1121007.AUML01000037_gene2025 6.31e-62 214.0 COG1106@1|root,COG1106@2|Bacteria,4PFP9@976|Bacteroidetes,1I7WT@117743|Flavobacteriia 976|Bacteroidetes S AAA ATPase domain - - - - - - - - - - - - - MHFCBNDO_02090 1133569.AHYZ01000154_gene2214 3.72e-09 57.0 COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,4HGAF@91061|Bacilli,3F4R3@33958|Lactobacillaceae 91061|Bacilli S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii MHFCBNDO_02091 1133569.AHYZ01000154_gene2213 8.07e-126 359.0 COG5340@1|root,COG5340@2|Bacteria,1TQSK@1239|Firmicutes,4HGQX@91061|Bacilli,3FBC6@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, AbiEi antitoxin - - - - - - - - - - - - AbiEi_4 MHFCBNDO_02095 1138822.PL11_10130 1.47e-27 101.0 COG1396@1|root,COG1396@2|Bacteria,1UN9D@1239|Firmicutes,4IU8A@91061|Bacilli,3FBZ4@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 MHFCBNDO_02096 1138822.PL11_10130 3.31e-10 56.2 COG1396@1|root,COG1396@2|Bacteria,1UN9D@1239|Firmicutes,4IU8A@91061|Bacilli,3FBZ4@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 MHFCBNDO_02097 1138822.PL11_10135 2.68e-75 225.0 COG4679@1|root,COG4679@2|Bacteria,1VB8K@1239|Firmicutes,4HKT7@91061|Bacilli,3F7HF@33958|Lactobacillaceae 91061|Bacilli S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 MHFCBNDO_02098 1138822.PL11_10140 9.42e-174 487.0 2B7B4@1|root,320E7@2|Bacteria,1V8P5@1239|Firmicutes,4HSR0@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02099 1138822.PL11_10145 9.84e-246 678.0 COG0542@1|root,COG0542@2|Bacteria,1UZ7G@1239|Firmicutes,4HJBJ@91061|Bacilli 91061|Bacilli O AAA domain (Cdc48 subfamily) - - - - - - - - - - - - AAA_2 MHFCBNDO_02100 543734.LCABL_21540 0.0 1044.0 COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,3F3NV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase MHFCBNDO_02101 543734.LCABL_21550 8.03e-229 629.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli,3F42Q@33958|Lactobacillaceae 91061|Bacilli F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK MHFCBNDO_02103 543734.LCABL_21570 1.13e-54 171.0 2AHIU@1|root,317WG@2|Bacteria,1U84D@1239|Firmicutes,4II1U@91061|Bacilli,3FAIH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02104 543734.LCABL_21580 0.0 954.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepDA - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 MHFCBNDO_02105 543734.LCABL_21590 5.02e-110 316.0 COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,3F6A3@33958|Lactobacillaceae 91061|Bacilli I Thioesterase superfamily ykhA - 3.1.2.20 ko:K01073 - - - - ko00000,ko01000 - - - 4HBT MHFCBNDO_02106 543734.LCABL_21600 0.0 1471.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,3F486@33958|Lactobacillaceae 91061|Bacilli L DNA helicase helD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 MHFCBNDO_02107 568703.LGG_01977 1.51e-29 105.0 2AX78@1|root,31P5Y@2|Bacteria,1U818@1239|Firmicutes,4IHYP@91061|Bacilli,3FAEP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02108 543734.LCABL_21610 0.0 1151.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,4H9Q5@91061|Bacilli,3F4AZ@33958|Lactobacillaceae 91061|Bacilli P TrkA C-terminal domain protein yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N MHFCBNDO_02109 543734.LCABL_21620 1.97e-230 632.0 COG2267@1|root,COG2267@2|Bacteria,1UEDT@1239|Firmicutes,4HF61@91061|Bacilli,3F47H@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepR - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 MHFCBNDO_02110 543734.LCABL_21630 4.52e-106 306.0 2C3KP@1|root,2Z802@2|Bacteria,1TQD1@1239|Firmicutes,4HBGA@91061|Bacilli,3F71P@33958|Lactobacillaceae 91061|Bacilli S Phage tail protein yjhE - - - - - - - - - - - - MHFCBNDO_02111 543734.LCABL_21640 6.29e-307 838.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp MHFCBNDO_02112 543734.LCABL_21650 5.73e-240 658.0 COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli,3F4VU@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase MHFCBNDO_02113 543734.LCABL_21660 4.03e-164 458.0 COG0406@1|root,COG0406@2|Bacteria,1TQWQ@1239|Firmicutes,4HF2N@91061|Bacilli,3F524@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpm2 - - - - - - - - - - - His_Phos_1 MHFCBNDO_02114 543734.LCABL_21670 0.0 1116.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4HAZG@91061|Bacilli,3F45H@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX MHFCBNDO_02115 543734.LCABL_21680 2.68e-174 486.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3F3MG@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein cysA - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_02116 543734.LCABL_21690 0.0 1088.0 COG0531@1|root,COG0531@2|Bacteria,1VTQI@1239|Firmicutes,4HU7Y@91061|Bacilli,3FBET@33958|Lactobacillaceae 91061|Bacilli E Amino Acid - - - - - - - - - - - - AA_permease_2 MHFCBNDO_02117 543734.LCABL_21700 5.76e-210 580.0 COG1597@1|root,COG1597@2|Bacteria,1V4PN@1239|Firmicutes,4HHJP@91061|Bacilli,3F3Z6@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat MHFCBNDO_02118 543734.LCABL_21730 4.57e-304 830.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,3F4B2@33958|Lactobacillaceae 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 MHFCBNDO_02119 543734.LCABL_21740 5.31e-169 479.0 COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HHQN@91061|Bacilli,3FC25@33958|Lactobacillaceae 91061|Bacilli G Polysaccharide deacetylase nodB3 - - - - - - - - - - - Polysacc_deac_1 MHFCBNDO_02120 1121344.JHZO01000003_gene831 7.36e-34 135.0 COG3274@1|root,COG3274@2|Bacteria,1V90B@1239|Firmicutes,24IC7@186801|Clostridia,3WRX3@541000|Ruminococcaceae 186801|Clostridia S Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 MHFCBNDO_02121 1139219.I569_00452 5.76e-60 227.0 COG0791@1|root,COG0791@2|Bacteria,1UNZW@1239|Firmicutes,4IUVQ@91061|Bacilli,4B60V@81852|Enterococcaceae 91061|Bacilli M NLP P60 protein - - - - - - - - - - - - - MHFCBNDO_02122 565655.ECBG_02869 4.88e-139 431.0 COG3757@1|root,COG3757@2|Bacteria,1VRSE@1239|Firmicutes,4HI01@91061|Bacilli,4B22J@81852|Enterococcaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25 MHFCBNDO_02123 1158607.UAU_04639 1.32e-74 248.0 COG3307@1|root,COG3307@2|Bacteria,1VANV@1239|Firmicutes,4IPYQ@91061|Bacilli,4B1Y1@81852|Enterococcaceae 91061|Bacilli M O-Antigen ligase - - - - - - - - - - - - Wzy_C MHFCBNDO_02124 1158607.UAU_04640 1.01e-98 303.0 COG0438@1|root,COG0438@2|Bacteria,1TPHK@1239|Firmicutes,4HAXV@91061|Bacilli,4B3BW@81852|Enterococcaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 MHFCBNDO_02125 1158607.UAU_04641 2.47e-185 536.0 COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,4HCW6@91061|Bacilli,4B4J4@81852|Enterococcaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score cps2I - - - - - - - - - - - Polysacc_synt MHFCBNDO_02126 1260356.D920_01305 6.35e-123 362.0 COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HCW0@91061|Bacilli,4B1HJ@81852|Enterococcaceae 91061|Bacilli M group 2 family protein - - - - - - - - - - - - Glycos_transf_2 MHFCBNDO_02127 543734.LCABL_12610 1e-152 438.0 COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,4HC1B@91061|Bacilli,3F6WH@33958|Lactobacillaceae 91061|Bacilli GM Male sterility protein - - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - Epimerase MHFCBNDO_02128 1158604.I591_01353 6.19e-132 378.0 COG1211@1|root,COG1211@2|Bacteria,1TS1B@1239|Firmicutes,4HHZZ@91061|Bacilli,4AZAT@81852|Enterococcaceae 91061|Bacilli I 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD MHFCBNDO_02129 565664.EFXG_02140 5.14e-147 421.0 COG3475@1|root,COG3475@2|Bacteria,1TT6A@1239|Firmicutes,4HE2E@91061|Bacilli,4B0MD@81852|Enterococcaceae 91061|Bacilli M LicD family licD3 - - ko:K07271 - - - - ko00000,ko01000 - - - LicD MHFCBNDO_02130 1140002.I570_02161 7.04e-106 315.0 COG1215@1|root,COG1215@2|Bacteria,1V1CB@1239|Firmicutes,4HHH7@91061|Bacilli,4B0ZP@81852|Enterococcaceae 91061|Bacilli M Glycosyl transferase family 2 wcaA - - - - - - - - - - - Glycos_transf_2 MHFCBNDO_02131 1423732.BALS01000012_gene1488 1.37e-249 695.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HB15@91061|Bacilli,3F5WM@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase cps2E - - - - - - - - - - - Bac_transf,CoA_binding_3 MHFCBNDO_02133 565655.ECBG_02757 8.61e-72 259.0 COG1376@1|root,COG1376@2|Bacteria,1UM6R@1239|Firmicutes,4ITS2@91061|Bacilli,4AZUX@81852|Enterococcaceae 91061|Bacilli S ErfK ybiS ycfS ynhG family protein - - - - - - - - - - - - SH3_8,YkuD MHFCBNDO_02134 226185.EF_2794 1.71e-64 225.0 2DQSR@1|root,338EM@2|Bacteria,1VAQX@1239|Firmicutes,4HM5B@91061|Bacilli,4B4C5@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - PMT_2 MHFCBNDO_02135 1123313.ATUT01000016_gene618 3.77e-12 74.7 COG1835@1|root,COG1835@2|Bacteria,1UXXI@1239|Firmicutes,3VQ6J@526524|Erysipelotrichia 526524|Erysipelotrichia I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 MHFCBNDO_02136 1158609.I586_01142 7.23e-126 385.0 COG1807@1|root,COG1807@2|Bacteria,1TZ29@1239|Firmicutes,4I895@91061|Bacilli,4B21E@81852|Enterococcaceae 91061|Bacilli M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 MHFCBNDO_02137 543734.LCABL_20250 1.58e-125 375.0 COG1680@1|root,COG1680@2|Bacteria,1V0GX@1239|Firmicutes,4HCXH@91061|Bacilli,3F4TH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase MHFCBNDO_02138 543734.LCABL_21850 2.5e-191 535.0 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,3F5GY@33958|Lactobacillaceae 91061|Bacilli M RmlD substrate binding domain cps2D - 5.1.3.2,5.1.3.25 ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 M00361,M00362,M00632 R00291,R02984,R10279 RC00289 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS00780 Epimerase,GDP_Man_Dehyd MHFCBNDO_02139 543734.LCABL_21860 6.51e-141 399.0 COG0765@1|root,COG0765@2|Bacteria,1UJM4@1239|Firmicutes,4HBAS@91061|Bacilli,3F3WJ@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 MHFCBNDO_02140 543734.LCABL_21870 5.85e-141 399.0 COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HFBH@91061|Bacilli,3F3XW@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnM GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 MHFCBNDO_02141 543734.LCABL_21880 8.33e-189 525.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli,3F4GG@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein glnH - - ko:K10039 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 MHFCBNDO_02142 543734.LCABL_21890 6.35e-174 485.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - - ko:K10041 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran MHFCBNDO_02143 543734.LCABL_21900 1.89e-228 630.0 2C6F0@1|root,32RH8@2|Bacteria,1V7ET@1239|Firmicutes,4HJDI@91061|Bacilli,3F4UC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02145 543734.LCABL_21920 3.91e-109 313.0 COG0735@1|root,COG0735@2|Bacteria,1V6RI@1239|Firmicutes,4HIGM@91061|Bacilli,3F6W3@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Fur family zur - - ko:K02076,ko:K03711 - - - - ko00000,ko03000 - - - FUR MHFCBNDO_02146 543734.LCABL_21930 9.35e-15 66.6 29QNJ@1|root,30BN7@2|Bacteria,1U8CS@1239|Firmicutes,4IIAR@91061|Bacilli,3FAUD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02147 543734.LCABL_21940 7.28e-144 405.0 COG0194@1|root,COG0194@2|Bacteria,1V8PW@1239|Firmicutes,4HJCB@91061|Bacilli,3F6N3@33958|Lactobacillaceae 91061|Bacilli F Guanylate kinase gmk2 - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin MHFCBNDO_02148 543734.LCABL_21950 6.72e-88 258.0 COG0454@1|root,COG0456@2|Bacteria,1UHQS@1239|Firmicutes,4IT2E@91061|Bacilli,3FBVW@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 MHFCBNDO_02149 543734.LCABL_21960 2.08e-187 532.0 COG0791@1|root,COG0791@2|Bacteria,1UVYK@1239|Firmicutes,4HDAX@91061|Bacilli,3F5PQ@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family spl - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 MHFCBNDO_02150 543734.LCABL_21970 1.55e-312 850.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,3F48J@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b MHFCBNDO_02151 543734.LCABL_21980 1.87e-221 611.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer MHFCBNDO_02152 543734.LCABL_21990 5.83e-73 219.0 COG0640@1|root,COG0640@2|Bacteria,1VFY4@1239|Firmicutes,4HP5T@91061|Bacilli,3F8JS@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5 MHFCBNDO_02153 543734.LCABL_22000 3.12e-222 612.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HHVC@91061|Bacilli,3F3QR@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE MHFCBNDO_02154 543734.LCABL_22010 0.0 1221.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,3F41N@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family malZ - 3.2.1.20,3.2.1.41 ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 - R00028,R00801,R00802,R02111,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - CBM48,GH13,GH31 - Alpha-amylase,Alpha-amylase_N MHFCBNDO_02155 543734.LCABL_22020 0.0 1588.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,3F4Z1@33958|Lactobacillaceae 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase MHFCBNDO_02156 543734.LCABL_22030 0.0 980.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,3F3PP@33958|Lactobacillaceae 91061|Bacilli F Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 MHFCBNDO_02157 543734.LCABL_22040 1.39e-279 764.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli,3F58E@33958|Lactobacillaceae 91061|Bacilli G Nucleotidyl transferase glgD - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase MHFCBNDO_02158 543734.LCABL_22050 1.18e-255 703.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,3F4IA@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase MHFCBNDO_02159 543734.LCABL_22060 0.0 1474.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli,3F4KT@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 MHFCBNDO_02160 543734.LCABL_22070 8.73e-262 715.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli,3F4BD@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 MHFCBNDO_02161 543734.LCABL_22080 5.44e-132 384.0 COG3764@1|root,COG3764@2|Bacteria,1VXZD@1239|Firmicutes,4HXV4@91061|Bacilli,3F9NX@33958|Lactobacillaceae 91061|Bacilli M Sortase family - - - - - - - - - - - - DUF5011,Sortase MHFCBNDO_02162 543734.LCABL_22090 1.29e-186 520.0 COG1284@1|root,COG1284@2|Bacteria,1TWZ5@1239|Firmicutes,4HD8R@91061|Bacilli,3F54A@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - DUF2179,YitT_membrane MHFCBNDO_02163 543734.LCABL_22100 1.12e-95 296.0 COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,4HBAN@91061|Bacilli,3F4MG@33958|Lactobacillaceae 91061|Bacilli G phosphatase activity fbp - 3.1.3.11 ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_2 MHFCBNDO_02164 543734.LCABL_22100 0.0 1017.0 COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,4HBAN@91061|Bacilli,3F4MG@33958|Lactobacillaceae 91061|Bacilli G phosphatase activity fbp - 3.1.3.11 ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_2 MHFCBNDO_02165 543734.LCABL_22110 1.94e-86 254.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F9SP@33958|Lactobacillaceae 91061|Bacilli P ArsC family spx2 - - ko:K16509 - - - - ko00000 - - - ArsC MHFCBNDO_02166 543734.LCABL_22120 0.0 1389.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F43D@33958|Lactobacillaceae 91061|Bacilli O associated with various cellular activities clpE - - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR MHFCBNDO_02167 543734.LCABL_22130 1.15e-185 515.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,3F3RT@33958|Lactobacillaceae 91061|Bacilli GM PHP domain protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - MHFCBNDO_02168 543734.LCABL_22140 5.65e-201 558.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr MHFCBNDO_02169 543734.LCABL_21790 2.16e-203 562.0 COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,3F4QS@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind MHFCBNDO_02170 543734.LCABL_22210 5.88e-259 708.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,3F3R6@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd MHFCBNDO_02171 543734.LCABL_21810 1.55e-140 396.0 COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,4HFQB@91061|Bacilli,3F4FN@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom MHFCBNDO_02172 543734.LCABL_22230 1.53e-208 576.0 COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli,3F4F8@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase MHFCBNDO_02173 1423816.BACQ01000050_gene1844 6.81e-93 276.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HCBG@91061|Bacilli,3F51J@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase rfbP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K13012,ko:K19428 - - - - ko00000,ko01000,ko01005 - - - Bac_transf,CoA_binding_3 MHFCBNDO_02174 543734.LCABL_22270 1.88e-176 495.0 COG1216@1|root,COG1216@2|Bacteria,1VAE1@1239|Firmicutes,4HM9Y@91061|Bacilli,3F941@33958|Lactobacillaceae 91061|Bacilli S Glycosyltransferase like family 2 - - - ko:K07011 - - - - ko00000 - - - Glycos_transf_2 MHFCBNDO_02175 543734.LCABL_22280 7.88e-306 838.0 COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,4HC84@91061|Bacilli,3F48Q@33958|Lactobacillaceae 91061|Bacilli S Membrane protein involved in the export of O-antigen and teichoic acid cps1C - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C MHFCBNDO_02176 543734.LCABL_02340 1.07e-139 399.0 COG3774@1|root,COG3774@2|Bacteria,1V9J7@1239|Firmicutes,4HIAM@91061|Bacilli,3F4U2@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase sugar-binding region containing DXD motif - - - - - - - - - - - - Caps_synth,Gly_transf_sug MHFCBNDO_02177 543734.LCABL_22300 1.82e-207 584.0 2DY4C@1|root,3483I@2|Bacteria,1W1D2@1239|Firmicutes,4HYAM@91061|Bacilli,3FAUV@33958|Lactobacillaceae 91061|Bacilli S O-antigen ligase like membrane protein - - - - - - - - - - - - - MHFCBNDO_02178 543734.LCABL_22310 2.26e-176 498.0 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,4HGSR@91061|Bacilli,3FBSG@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 MHFCBNDO_02179 543734.LCABL_22320 1.78e-261 718.0 COG0438@1|root,COG0438@2|Bacteria,1TR6R@1239|Firmicutes,4HEIZ@91061|Bacilli,3F7BB@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 MHFCBNDO_02180 543734.LCABL_22330 3.64e-293 799.0 COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,4IPU2@91061|Bacilli,3F5EQ@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF1972) rgpAc - - ko:K12996 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - DUF1972,Glycos_transf_1 MHFCBNDO_02181 543734.LCABL_22340 1.2e-161 454.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,3F4BM@33958|Lactobacillaceae 91061|Bacilli D Capsular exopolysaccharide family ywqD - - - - - - - - - - - AAA_31,ParA MHFCBNDO_02182 543734.LCABL_22350 7.89e-184 515.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,3F4M5@33958|Lactobacillaceae 91061|Bacilli M biosynthesis protein epsB - - - - - - - - - - - GNVR,Wzz MHFCBNDO_02183 543734.LCABL_22360 2.13e-169 473.0 COG2755@1|root,COG2755@2|Bacteria,1UI5G@1239|Firmicutes,4ISEF@91061|Bacilli,3F652@33958|Lactobacillaceae 91061|Bacilli E lipolytic protein G-D-S-L family - - - - - - - - - - - - - MHFCBNDO_02184 334390.LAF_0675 2.45e-245 673.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve MHFCBNDO_02185 543734.LCABL_22370 8.13e-104 301.0 COG4708@1|root,COG4708@2|Bacteria,1V22G@1239|Firmicutes,4HGG2@91061|Bacilli,3F6CG@33958|Lactobacillaceae 91061|Bacilli S QueT transporter ccl GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - QueT MHFCBNDO_02186 543734.LCABL_22380 2.57e-160 450.0 COG1028@1|root,COG1028@2|Bacteria,1U8IC@1239|Firmicutes,4HC26@91061|Bacilli,3F4X3@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 MHFCBNDO_02187 543734.LCABL_22390 8.55e-49 155.0 2E68Y@1|root,330X0@2|Bacteria,1VFBF@1239|Firmicutes,4HP3V@91061|Bacilli,3F810@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2829) XK27_01315 - - - - - - - - - - - DUF2829 MHFCBNDO_02188 543734.LCABL_22400 1.32e-63 194.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 MHFCBNDO_02189 543734.LCABL_22410 6.17e-151 424.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F4IS@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpm5 - - - - - - - - - - - His_Phos_1 MHFCBNDO_02190 543734.LCABL_22420 2.59e-229 632.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,3F4GM@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppF - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY MHFCBNDO_02191 543734.LCABL_22430 2.03e-250 687.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3F41T@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD - - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY MHFCBNDO_02192 543734.LCABL_22440 3.01e-227 627.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,3F3W3@33958|Lactobacillaceae 91061|Bacilli EP ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N MHFCBNDO_02193 543734.LCABL_22450 1.4e-208 578.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,3F42T@33958|Lactobacillaceae 91061|Bacilli P ABC-type dipeptide oligopeptide nickel transport systems, permease components oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 MHFCBNDO_02194 543734.LCABL_22460 0.0 1046.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 MHFCBNDO_02195 543734.LCABL_22470 0.0 876.0 COG0477@1|root,COG2814@2|Bacteria,1VSAB@1239|Firmicutes,4HECQ@91061|Bacilli,3FCCN@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 MHFCBNDO_02196 543734.LCABL_22490 4.1e-130 369.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F4EW@33958|Lactobacillaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C MHFCBNDO_02197 543734.LCABL_22500 1.34e-170 476.0 COG1556@1|root,COG1556@2|Bacteria,1UZAK@1239|Firmicutes,4HH3R@91061|Bacilli,3F4UV@33958|Lactobacillaceae 91061|Bacilli S LUD domain lutC - - ko:K00782 - - - - ko00000 - - - LUD_dom MHFCBNDO_02198 543734.LCABL_22510 0.0 995.0 COG1139@1|root,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,3F4IV@33958|Lactobacillaceae 91061|Bacilli C 4Fe-4S dicluster domain lutB - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_8,LUD_dom MHFCBNDO_02199 543734.LCABL_22520 1.7e-190 528.0 COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli,3F4GX@33958|Lactobacillaceae 91061|Bacilli C Cysteine-rich domain lutA - - ko:K18928 - - - - ko00000 - - - CCG MHFCBNDO_02200 1423732.BALS01000017_gene1752 2.39e-109 317.0 2AYWY@1|root,30B2F@2|Bacteria,1U7F5@1239|Firmicutes,4IHB5@91061|Bacilli,3F9II@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02201 543734.LCABL_22540 1.09e-68 208.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli 91061|Bacilli G Phosphotransferase system cellobiose-specific component IIA - - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA MHFCBNDO_02202 543734.LCABL_22550 4.92e-266 728.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4H9V2@91061|Bacilli,3F4FK@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) ybhE - - ko:K09963 - - - - ko00000 - - - DUF871 MHFCBNDO_02203 543734.LCABL_22560 1.62e-90 265.0 2DQNY@1|root,337UX@2|Bacteria,1VEZ0@1239|Firmicutes,4HPE2@91061|Bacilli,3F69F@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF3284) - - - - - - - - - - - - DUF3284 MHFCBNDO_02205 543734.LCABL_22580 0.0 917.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F4VG@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane chbC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC MHFCBNDO_02206 543734.LCABL_22590 0.0 1500.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,3F3RU@33958|Lactobacillaceae 91061|Bacilli G alpha-galactosidase galA - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase MHFCBNDO_02207 543734.LCABL_22600 2.13e-173 484.0 COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,4HFN2@91061|Bacilli,3F4KR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0246 family XK27_08125 - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD MHFCBNDO_02208 543734.LCABL_22610 5.88e-176 490.0 COG3860@1|root,COG3860@2|Bacteria,1TPHH@1239|Firmicutes,4HCHE@91061|Bacilli,3F56B@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2087) - - - - - - - - - - - - DUF2087,GerE MHFCBNDO_02209 543734.LCABL_22620 0.0 1697.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,3F5WR@33958|Lactobacillaceae 91061|Bacilli L Helix-hairpin-helix containing domain - - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,UvrD_C_2 MHFCBNDO_02210 568703.LGG_02083 4.36e-103 302.0 2AGPG@1|root,316X2@2|Bacteria,1U7BQ@1239|Firmicutes,4IH6V@91061|Bacilli,3F9AE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02211 568703.LGG_02085 9.27e-77 236.0 29Q1U@1|root,30B0E@2|Bacteria,1U7CC@1239|Firmicutes,4IH7Q@91061|Bacilli,3F9CG@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL MHFCBNDO_02212 543734.LCABL_22650 6.84e-186 517.0 COG0524@1|root,COG0524@2|Bacteria,1TSST@1239|Firmicutes,4HGU3@91061|Bacilli,3F7U3@33958|Lactobacillaceae 91061|Bacilli G pfkB family carbohydrate kinase frlD1 - 2.7.1.218 ko:K10710 - - R08124 RC00002,RC00017 ko00000,ko01000 - - - PfkB MHFCBNDO_02213 543734.LCABL_22660 1.52e-130 384.0 COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,4HB8X@91061|Bacilli,3F4TR@33958|Lactobacillaceae 91061|Bacilli EQ Hydantoinase/oxoprolinase N-terminal region hyuA - - - - - - - - - - - Hydant_A_N,Hydantoinase_A MHFCBNDO_02214 543734.LCABL_22690 6.74e-176 492.0 29Q4F@1|root,30B35@2|Bacteria,1U7G9@1239|Firmicutes,4IHCF@91061|Bacilli,3F9KY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02215 543734.LCABL_22700 0.0 1349.0 COG1479@1|root,COG1479@2|Bacteria,1TPAT@1239|Firmicutes,4HPJ0@91061|Bacilli,3FB8C@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1524) - - - - - - - - - - - - DUF1524,DUF262 MHFCBNDO_02216 936140.AEOT01000008_gene249 1.21e-75 244.0 COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes,4HUTA@91061|Bacilli,3F718@33958|Lactobacillaceae 91061|Bacilli V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S MHFCBNDO_02217 543734.LCABL_22720 4.1e-222 612.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HDHJ@91061|Bacilli,3FC9T@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_5,Phage_integrase MHFCBNDO_02218 1231377.C426_1885 3.63e-82 257.0 COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes,4I4F9@91061|Bacilli,1YC2Y@1357|Lactococcus 91061|Bacilli V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S MHFCBNDO_02219 1123312.KB904581_gene1112 1.11e-251 706.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase MHFCBNDO_02220 543734.LCABL_22760 0.0 1859.0 COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4HB5A@91061|Bacilli,3F50Q@33958|Lactobacillaceae 91061|Bacilli V Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoR124_C,HSDR_N,ResIII MHFCBNDO_02221 543734.LCABL_22770 3.16e-98 289.0 2AYN8@1|root,31QSR@2|Bacteria,1V7X1@1239|Firmicutes,4HIZR@91061|Bacilli,3F859@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02222 543734.LCABL_22790 2.02e-270 741.0 2DSXT@1|root,32UTZ@2|Bacteria,1VRUF@1239|Firmicutes,4HTM0@91061|Bacilli,3FB9G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF998 MHFCBNDO_02223 1423732.BALS01000016_gene1697 0.0 1161.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts26BCA - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC MHFCBNDO_02224 543734.LCABL_22820 0.0 1152.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459,Malt_amylase_C MHFCBNDO_02225 543734.LCABL_22830 1.75e-231 638.0 COG1609@1|root,COG1609@2|Bacteria,1TRHK@1239|Firmicutes,4HB9P@91061|Bacilli,3F5FI@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding proteins and sugar binding domain of LacI family purR2 - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 MHFCBNDO_02226 543734.LCABL_22840 0.0 1042.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,3F4UD@33958|Lactobacillaceae 91061|Bacilli G invertase scrB - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N MHFCBNDO_02227 543734.LCABL_22880 7e-210 580.0 COG0702@1|root,COG0702@2|Bacteria,1UY7W@1239|Firmicutes,4HDIS@91061|Bacilli,3F4M7@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10,NmrA MHFCBNDO_02228 543734.LCABL_22890 4.81e-298 811.0 COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,4HDKI@91061|Bacilli,3F3PA@33958|Lactobacillaceae 91061|Bacilli M cyclopropane-fatty-acyl-phospholipid synthase cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS MHFCBNDO_02229 543734.LCABL_22900 8.04e-183 508.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,3F496@33958|Lactobacillaceae 91061|Bacilli I alpha subunit accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA MHFCBNDO_02230 543734.LCABL_22910 1.02e-192 535.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,3F3T6@33958|Lactobacillaceae 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans MHFCBNDO_02231 543734.LCABL_22920 0.0 889.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,3F3PT@33958|Lactobacillaceae 91061|Bacilli I Acetyl-CoA carboxylase biotin carboxylase subunit accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 MHFCBNDO_02232 543734.LCABL_22930 3.23e-98 285.0 COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli,3F5EE@33958|Lactobacillaceae 91061|Bacilli I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA MHFCBNDO_02233 543734.LCABL_22940 2.14e-88 261.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,3F7M1@33958|Lactobacillaceae 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl MHFCBNDO_02234 543734.LCABL_22950 3.31e-282 772.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,3F51H@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt MHFCBNDO_02235 543734.LCABL_22960 8.26e-164 459.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,3F4RI@33958|Lactobacillaceae 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 MHFCBNDO_02236 543734.LCABL_22970 2.82e-208 577.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,3F3W9@33958|Lactobacillaceae 91061|Bacilli I Malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 MHFCBNDO_02237 543734.LCABL_22980 9.2e-220 608.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,3F4PC@33958|Lactobacillaceae 91061|Bacilli S Nitronate monooxygenase fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO MHFCBNDO_02238 543734.LCABL_22990 1.38e-45 147.0 COG0236@1|root,COG0236@2|Bacteria,1VGIY@1239|Firmicutes,4HP0V@91061|Bacilli,3F7ZJ@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding MHFCBNDO_02239 543734.LCABL_23000 3.96e-226 623.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,3F3XP@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C MHFCBNDO_02240 543734.LCABL_23010 2.44e-99 288.0 COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,4IR3W@91061|Bacilli,3FC7M@33958|Lactobacillaceae 91061|Bacilli K Winged helix DNA-binding domain - - - - - - - - - - - - MarR MHFCBNDO_02241 543734.LCABL_23020 6.79e-95 277.0 COG0764@1|root,COG0764@2|Bacteria,1V3UN@1239|Firmicutes,4HHYD@91061|Bacilli,3F77T@33958|Lactobacillaceae 91061|Bacilli I FabA-like domain - - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA MHFCBNDO_02242 543734.LCABL_23030 1.47e-245 673.0 COG2021@1|root,COG2021@2|Bacteria,1UM05@1239|Firmicutes,4ITNF@91061|Bacilli,3F97M@33958|Lactobacillaceae 91061|Bacilli E Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 MHFCBNDO_02243 543734.LCABL_23040 1.86e-288 787.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4H9TR@91061|Bacilli,3F4VF@33958|Lactobacillaceae 91061|Bacilli C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH MHFCBNDO_02244 641146.HMPREF9020_01154 4.71e-302 823.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 MHFCBNDO_02245 543734.LCABL_23070 2.84e-63 193.0 COG4367@1|root,COG4367@2|Bacteria,1VGC1@1239|Firmicutes,4HQJ6@91061|Bacilli,3F89N@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2316) - - - - - - - - - - - - DUF2316 MHFCBNDO_02246 543734.LCABL_23080 1.35e-88 260.0 COG1846@1|root,COG1846@2|Bacteria,1VMZX@1239|Firmicutes,4HMTC@91061|Bacilli,3FBM2@33958|Lactobacillaceae 91061|Bacilli K MarR family - - - ko:K18909 - M00705 - - ko00000,ko00002,ko01504,ko03000 - - - MarR,MarR_2 MHFCBNDO_02247 1423734.JCM14202_162 5.76e-14 79.0 COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,3FBEE@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic tcaA - - ko:K21463 - - - - ko00000 - - - zf-ribbon_3,zinc_ribbon_2 MHFCBNDO_02248 543734.LCABL_23100 2.79e-213 592.0 COG0627@1|root,COG0627@2|Bacteria,1V856@1239|Firmicutes,4HVCY@91061|Bacilli,3F5Y5@33958|Lactobacillaceae 91061|Bacilli S Putative esterase - - - - - - - - - - - - Esterase MHFCBNDO_02249 543734.LCABL_23110 1.83e-256 704.0 28USJ@1|root,2ZGWS@2|Bacteria,1W533@1239|Firmicutes,4I1UJ@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - zinc_ribbon_2 MHFCBNDO_02250 543734.LCABL_23120 1.47e-136 386.0 COG1846@1|root,COG1846@2|Bacteria,1VF51@1239|Firmicutes,4HM7R@91061|Bacilli,3F725@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR,MarR_2 MHFCBNDO_02251 543734.LCABL_23130 0.0 1115.0 COG1132@1|root,COG1132@2|Bacteria,1TSY4@1239|Firmicutes,4HAJQ@91061|Bacilli,3FC4S@33958|Lactobacillaceae 91061|Bacilli V ABC transporter lmrA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 3.6.3.44 ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.123,3.A.1.21 - - ABC_membrane,ABC_tran MHFCBNDO_02252 543734.LCABL_23140 3.85e-108 311.0 COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,4HHQT@91061|Bacilli,3F4BS@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX MHFCBNDO_02253 543734.LCABL_23150 1.91e-167 467.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,3F3SK@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 MHFCBNDO_02254 568703.LGG_02139 4.74e-30 107.0 2AWRG@1|root,31NNE@2|Bacteria,1U7XJ@1239|Firmicutes,4IHUY@91061|Bacilli,3FAAP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02255 543734.LCABL_23170 1.09e-209 585.0 COG4640@1|root,COG4640@2|Bacteria,1VIMB@1239|Firmicutes,4HP7R@91061|Bacilli,3F7Z9@33958|Lactobacillaceae 91061|Bacilli S zinc-ribbon domain - - - - - - - - - - - - zf-ribbon_3,zinc_ribbon_2 MHFCBNDO_02256 543734.LCABL_23180 2.41e-261 716.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX - - - - - - - - - - - Beta-lactamase,SLH MHFCBNDO_02257 543734.LCABL_23190 4.01e-240 662.0 COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,3F46E@33958|Lactobacillaceae 91061|Bacilli K AI-2E family transporter ydbI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport MHFCBNDO_02258 543734.LCABL_23200 4.31e-166 464.0 COG3764@1|root,COG3764@2|Bacteria,1V4ZG@1239|Firmicutes,4HMUE@91061|Bacilli,3FBG7@33958|Lactobacillaceae 91061|Bacilli M Sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase MHFCBNDO_02259 543734.LCABL_23210 1.41e-85 253.0 COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,4HNK7@91061|Bacilli,3F4GH@33958|Lactobacillaceae 91061|Bacilli S Teichoic acid glycosylation protein gtcA2 - - - - - - - - - - - GtrA MHFCBNDO_02260 543734.LCABL_23220 7.62e-219 604.0 COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,4HJ8D@91061|Bacilli,3F5ND@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat MHFCBNDO_02261 543734.LCABL_23230 0.0 1155.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family - - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N MHFCBNDO_02262 543734.LCABL_23250 3.51e-216 596.0 COG2113@1|root,COG2113@2|Bacteria,1TP82@1239|Firmicutes,4H9MM@91061|Bacilli,3F4B3@33958|Lactobacillaceae 91061|Bacilli E glycine betaine gbuC - - ko:K02001,ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC MHFCBNDO_02263 543734.LCABL_23260 5.82e-189 526.0 COG4176@1|root,COG4176@2|Bacteria,1UHRI@1239|Firmicutes,4IS7D@91061|Bacilli,3F4W7@33958|Lactobacillaceae 91061|Bacilli E glycine betaine gbuB - - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 MHFCBNDO_02264 543734.LCABL_23270 9.19e-285 779.0 COG4175@1|root,COG4175@2|Bacteria,1UHNE@1239|Firmicutes,4HA9P@91061|Bacilli,3FC38@33958|Lactobacillaceae 91061|Bacilli E glycine betaine gbuA - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS MHFCBNDO_02265 543734.LCABL_23280 1.63e-175 489.0 COG1489@1|root,COG1489@2|Bacteria,1V1GZ@1239|Firmicutes,4HCPN@91061|Bacilli,3F4KV@33958|Lactobacillaceae 91061|Bacilli S Belongs to the SfsA family sfsA - - ko:K06206 - - - - ko00000 - - - SfsA MHFCBNDO_02266 543734.LCABL_23290 2.6e-96 281.0 COG0589@1|root,COG0589@2|Bacteria,1U62R@1239|Firmicutes,4IFRW@91061|Bacilli,3F6W5@33958|Lactobacillaceae 91061|Bacilli T Universal stress protein family usp1 - - - - - - - - - - - Usp MHFCBNDO_02267 543734.LCABL_23300 0.0 868.0 COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,4HAB0@91061|Bacilli,3F3S7@33958|Lactobacillaceae 91061|Bacilli S ATP-grasp enzyme yxbA - 6.3.1.12 ko:K17810 - - - - ko00000,ko01000 - - - CPSase_L_D2,Dala_Dala_lig_C MHFCBNDO_02268 543734.LCABL_23310 4.1e-191 532.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,3F44T@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB - 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N MHFCBNDO_02269 543734.LCABL_23320 0.0 986.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,4H9R7@91061|Bacilli,3F3UF@33958|Lactobacillaceae 91061|Bacilli E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N MHFCBNDO_02270 543734.LCABL_23330 1.6e-290 793.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,3F5BM@33958|Lactobacillaceae 91061|Bacilli E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 MHFCBNDO_02271 543734.LCABL_23340 0.0 867.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,3F48V@33958|Lactobacillaceae 91061|Bacilli E Belongs to the aspartokinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 MHFCBNDO_02272 543734.LCABL_23350 1.86e-269 748.0 COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,4HA0C@91061|Bacilli,3F5TM@33958|Lactobacillaceae 91061|Bacilli S SPFH domain / Band 7 family floL - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot MHFCBNDO_02273 568703.LGG_02158 2.67e-51 166.0 2ESCD@1|root,33JX6@2|Bacteria,1VQB2@1239|Firmicutes,4HT0C@91061|Bacilli,3F9Y6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02274 543734.LCABL_23370 1.23e-221 614.0 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC4N@91061|Bacilli,3FCB3@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase system, EIIC pfoSR - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 MHFCBNDO_02275 543734.LCABL_23380 1.54e-220 610.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HCIS@91061|Bacilli,3F4US@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhD - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C MHFCBNDO_02276 543734.LCABL_23390 3.99e-278 760.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspC - 2.6.1.57 ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 M00024,M00025,M00034,M00040,M00525 R00694,R00734,R01731,R04467,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 MHFCBNDO_02277 543734.LCABL_23400 1.21e-65 200.0 2BNCG@1|root,32H06@2|Bacteria,1U7X9@1239|Firmicutes,4IHUN@91061|Bacilli,3FAAB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02278 543734.LCABL_23410 3.67e-163 457.0 COG2013@1|root,COG2013@2|Bacteria,1TPN2@1239|Firmicutes,4HHYG@91061|Bacilli,3F4J7@33958|Lactobacillaceae 91061|Bacilli S Mitochondrial biogenesis AIM24 WQ51_05710 - - - - - - - - - - - AIM24 MHFCBNDO_02279 543734.LCABL_23420 6.61e-93 270.0 COG0537@1|root,COG0537@2|Bacteria,1VB6J@1239|Firmicutes,4HIE1@91061|Bacilli,3FCD8@33958|Lactobacillaceae 91061|Bacilli FG Scavenger mRNA decapping enzyme C-term binding - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT MHFCBNDO_02280 543734.LCABL_23430 0.0 1285.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,3F3NT@33958|Lactobacillaceae 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 MHFCBNDO_02282 543734.LCABL_23460 6.08e-256 702.0 2EQYH@1|root,33II5@2|Bacteria,1VMH1@1239|Firmicutes,4HUIK@91061|Bacilli,3F5E7@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos MHFCBNDO_02283 543734.LCABL_23470 9.76e-203 563.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F3JM@33958|Lactobacillaceae 91061|Bacilli H 1,4-dihydroxy-2-naphthoate menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA MHFCBNDO_02284 543734.LCABL_23480 2.67e-225 621.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,3F4GC@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt MHFCBNDO_02285 543734.LCABL_23490 1.92e-283 775.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase MHFCBNDO_02286 543734.LCABL_23500 9.96e-212 585.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein ysdB - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 MHFCBNDO_02287 543734.LCABL_23510 2.05e-277 761.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,3F3KA@33958|Lactobacillaceae 91061|Bacilli CP ABC-2 family transporter protein ysdA - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 MHFCBNDO_02288 543734.LCABL_23520 6.81e-86 253.0 COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,4HKSY@91061|Bacilli,3F78Z@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR MHFCBNDO_02289 543734.LCABL_23530 9.19e-209 577.0 COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,4HB36@91061|Bacilli,3F4BW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter CcmA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_02290 543734.LCABL_23540 3.68e-144 407.0 COG1835@1|root,COG1835@2|Bacteria,1UG9X@1239|Firmicutes,4IGYH@91061|Bacilli,3F8XZ@33958|Lactobacillaceae 91061|Bacilli I ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_5 MHFCBNDO_02291 543734.LCABL_23550 5.9e-187 519.0 COG1028@1|root,COG1028@2|Bacteria,1TRQC@1239|Firmicutes,4HD7P@91061|Bacilli,3F4FH@33958|Lactobacillaceae 91061|Bacilli IQ reductase gdh - 1.1.1.47 ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 - R01520,R01521 RC00066 ko00000,ko00001,ko01000 - - - adh_short_C2 MHFCBNDO_02292 543734.LCABL_23560 9.75e-256 702.0 COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli,3F4ZR@33958|Lactobacillaceae 91061|Bacilli C Belongs to the AlaDH PNT family ald1 - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N MHFCBNDO_02293 543734.LCABL_23570 2.06e-236 651.0 COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli,3F5KK@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C MHFCBNDO_02294 1423732.BALS01000018_gene1802 0.0 1053.0 COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,4HB4S@91061|Bacilli,3F3KY@33958|Lactobacillaceae 91061|Bacilli S OPT oligopeptide transporter protein - - - - - - - - - - - - OPT MHFCBNDO_02295 543734.LCABL_23600 3.4e-82 243.0 2E6A2@1|root,3182Z@2|Bacteria,1V931@1239|Firmicutes,4HNND@91061|Bacilli,3F77F@33958|Lactobacillaceae 91061|Bacilli S Coenzyme PQQ synthesis protein D (PqqD) - - - - - - - - - - - - PqqD MHFCBNDO_02296 543734.LCABL_23610 0.0 974.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD3 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 MHFCBNDO_02297 543734.LCABL_23620 0.0 885.0 COG1249@1|root,COG1249@2|Bacteria,1TS0Z@1239|Firmicutes,4HBYB@91061|Bacilli,3F3K2@33958|Lactobacillaceae 91061|Bacilli C Glutathione reductase gshR3 - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim MHFCBNDO_02298 543734.LCABL_23630 6.16e-316 863.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily lmrB - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 MHFCBNDO_02299 543734.LCABL_23650 2.23e-119 342.0 COG1309@1|root,COG1309@2|Bacteria,1UVV7@1239|Firmicutes,4I435@91061|Bacilli,3F8HZ@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - ko:K18939 - M00715 - - ko00000,ko00002,ko03000 - - - TetR_N MHFCBNDO_02300 543734.LCABL_23660 0.0 1007.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglH - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 MHFCBNDO_02301 543734.LCABL_23670 0.0 1135.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system bglP - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC MHFCBNDO_02302 543734.LCABL_23680 3.99e-197 547.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,3F4SJ@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain bglG4 - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD MHFCBNDO_02303 543734.LCABL_23690 0.0 1009.0 COG1132@1|root,COG1132@2|Bacteria,1UHQP@1239|Firmicutes,4HC57@91061|Bacilli,3F5XV@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region msbA9 - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran MHFCBNDO_02304 543734.LCABL_23700 0.0 1093.0 COG4988@1|root,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,4HCDA@91061|Bacilli,3F4VY@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter transmembrane region cydD1 - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran,DUF454 MHFCBNDO_02305 543734.LCABL_23710 2.59e-97 283.0 COG5341@1|root,COG5341@2|Bacteria,1VCR8@1239|Firmicutes,4HKP0@91061|Bacilli,3FBC0@33958|Lactobacillaceae 91061|Bacilli S NusG domain II - - - - - - - - - - - - NusG_II MHFCBNDO_02306 568703.LGG_02198 1.35e-208 583.0 COG3409@1|root,COG3409@2|Bacteria,1V2YC@1239|Firmicutes,4HFNB@91061|Bacilli,3F6TH@33958|Lactobacillaceae 91061|Bacilli M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - - MHFCBNDO_02307 543734.LCABL_23750 1.01e-151 427.0 28XJS@1|root,2ZJGW@2|Bacteria,1W4NV@1239|Firmicutes,4I15N@91061|Bacilli,3F6XN@33958|Lactobacillaceae 91061|Bacilli S CRISPR-associated protein (Cas_Csn2) - - - - - - - - - - - - Cas_Csn2 MHFCBNDO_02308 543734.LCABL_23760 2.84e-62 191.0 COG3512@1|root,COG3512@2|Bacteria,1VEH4@1239|Firmicutes,4HNYR@91061|Bacilli,3F7KD@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas2 - - ko:K09951 - - - - ko00000,ko02048 - - - CRISPR_Cas2 MHFCBNDO_02309 543734.LCABL_23770 9.98e-215 593.0 COG1518@1|root,COG1518@2|Bacteria,1TT0J@1239|Firmicutes,4HC5E@91061|Bacilli,3F3RW@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1 MHFCBNDO_02310 543734.LCABL_23780 2.31e-308 880.0 COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,4HE0R@91061|Bacilli,3F554@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer cas9 - - ko:K09952 - - - - ko00000,ko01000,ko02048 - - - Cas9-BH,Cas9_PI,Cas9_REC,HNH_4 MHFCBNDO_02311 543734.LCABL_23780 0.0 1379.0 COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,4HE0R@91061|Bacilli,3F554@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer cas9 - - ko:K09952 - - - - ko00000,ko01000,ko02048 - - - Cas9-BH,Cas9_PI,Cas9_REC,HNH_4 MHFCBNDO_02312 543734.LCABL_23790 6.56e-181 504.0 29PFB@1|root,30ADG@2|Bacteria,1U6HW@1239|Firmicutes,4IGA7@91061|Bacilli,3F7Y8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02313 543734.LCABL_23800 3.11e-274 750.0 COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,4HITC@91061|Bacilli,3F50M@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - MHFCBNDO_02314 543734.LCABL_23810 1.12e-82 244.0 COG5294@1|root,COG5294@2|Bacteria,1VF0I@1239|Firmicutes,4HPC2@91061|Bacilli,3F83V@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 MHFCBNDO_02315 543734.LCABL_23820 6.43e-66 201.0 2DZIG@1|root,32VBI@2|Bacteria,1VIUB@1239|Firmicutes,4HRZP@91061|Bacilli,3F7EN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF4870 MHFCBNDO_02316 543734.LCABL_23830 0.0 1124.0 COG4987@1|root,COG4987@2|Bacteria,1UHN5@1239|Firmicutes,4HAAB@91061|Bacilli,3F4PG@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC cydD - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran MHFCBNDO_02317 543734.LCABL_23840 0.0 1125.0 COG4988@1|root,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,4HAN0@91061|Bacilli,3F451@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD cydC GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran MHFCBNDO_02318 543734.LCABL_23850 5.88e-232 639.0 COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,4H9KF@91061|Bacilli,3F40S@33958|Lactobacillaceae 91061|Bacilli C Cytochrome d ubiquinol oxidase subunit II cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iYO844.BSU38750 Cyt_bd_oxida_II MHFCBNDO_02319 543734.LCABL_23860 0.0 965.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,3F4MJ@33958|Lactobacillaceae 91061|Bacilli C ubiquinol oxidase cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I MHFCBNDO_02321 543734.LCABL_23870 1.12e-301 824.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,3F45P@33958|Lactobacillaceae 91061|Bacilli F pyrimidine-nucleoside phosphorylase pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C MHFCBNDO_02322 543734.LCABL_23880 1.79e-243 669.0 COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,4HCES@91061|Bacilli,3F5RC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism add - 3.5.4.2,3.5.4.4 ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 M00236 R01244,R01560,R02556 RC00477 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - A_deaminase MHFCBNDO_02323 543734.LCABL_23890 6.98e-53 166.0 2900D@1|root,30NTF@2|Bacteria,1U66C@1239|Firmicutes,4IFWI@91061|Bacilli,3F8DT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02324 543734.LCABL_23900 7.07e-112 321.0 2CCK1@1|root,309S4@2|Bacteria,1U5KG@1239|Firmicutes,4IFBA@91061|Bacilli,3F64Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02325 543734.LCABL_23910 6.71e-34 116.0 29PYW@1|root,30AXC@2|Bacteria,1U786@1239|Firmicutes,4IH32@91061|Bacilli,3F93Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02326 543734.LCABL_23930 1.72e-213 590.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA MHFCBNDO_02327 543734.LCABL_23940 3.45e-144 406.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,3F5KA@33958|Lactobacillaceae 91061|Bacilli L glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco MHFCBNDO_02328 543734.LCABL_23950 9.59e-101 292.0 COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,4HNHG@91061|Bacilli,3F4Z0@33958|Lactobacillaceae 91061|Bacilli T universal stress protein usp5 - - - - - - - - - - - Usp MHFCBNDO_02329 568703.LGG_02218 3.25e-74 223.0 29Q5Z@1|root,30B4V@2|Bacteria,1U7J6@1239|Firmicutes,4IHG0@91061|Bacilli,3F9SW@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_31 MHFCBNDO_02330 543734.LCABL_23970 2.13e-185 515.0 COG2365@1|root,COG2365@2|Bacteria,1VBGE@1239|Firmicutes,4HN6J@91061|Bacilli,3FBJY@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family ptp3 - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 MHFCBNDO_02331 543734.LCABL_23980 5.06e-282 769.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,3F5I3@33958|Lactobacillaceae 91061|Bacilli C Domain of unknown function (DUF1730) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 MHFCBNDO_02332 543734.LCABL_23990 1.54e-84 249.0 29PE3@1|root,30AC9@2|Bacteria,1U6GD@1239|Firmicutes,4IG8H@91061|Bacilli,3F7V6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02333 543734.LCABL_24010 7.09e-113 325.0 COG1268@1|root,COG1268@2|Bacteria,1VAAD@1239|Firmicutes,4HI8T@91061|Bacilli,3F6YG@33958|Lactobacillaceae 91061|Bacilli S BioY family bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY MHFCBNDO_02334 543734.LCABL_24020 5.77e-93 271.0 COG0789@1|root,COG0789@2|Bacteria,1VAAP@1239|Firmicutes,4HKZ9@91061|Bacilli,3F6JI@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance adhR - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 MHFCBNDO_02335 543734.LCABL_24030 2.59e-107 309.0 COG0716@1|root,COG0716@2|Bacteria,1V465@1239|Firmicutes,4HN5X@91061|Bacilli,3F7H7@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin - - - - - - - - - - - - Flavodoxin_4 MHFCBNDO_02336 543734.LCABL_24040 2.68e-253 694.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3F42F@33958|Lactobacillaceae 91061|Bacilli E alcohol dehydrogenase adh2 - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N MHFCBNDO_02337 543734.LCABL_24050 1.59e-147 416.0 COG0702@1|root,COG0702@2|Bacteria,1UJSC@1239|Firmicutes,4HCVT@91061|Bacilli,3F4ZZ@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 MHFCBNDO_02339 543734.LCABL_24080 5.62e-132 374.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 MHFCBNDO_02340 543734.LCABL_24090 9.78e-139 404.0 COG3103@1|root,COG3103@2|Bacteria,1VB6H@1239|Firmicutes,4I1GZ@91061|Bacilli,3F66H@33958|Lactobacillaceae 91061|Bacilli T Sh3 type 3 domain protein - - - - - - - - - - - - LysM,SLAP MHFCBNDO_02341 543734.LCABL_24100 6.72e-152 426.0 COG0518@1|root,COG0518@2|Bacteria,1UAH0@1239|Firmicutes,4HHTX@91061|Bacilli,3F4AV@33958|Lactobacillaceae 91061|Bacilli F glutamine amidotransferase - - - - - - - - - - - - GATase MHFCBNDO_02342 543734.LCABL_24110 1.23e-172 482.0 COG4295@1|root,COG4295@2|Bacteria,1VAHN@1239|Firmicutes,4HY6J@91061|Bacilli,3FBBD@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2263) - - - - - - - - - - - - DUF2263 MHFCBNDO_02343 543734.LCABL_24120 0.0 893.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3TX@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain yhdP - - - - - - - - - - - CBS,CorC_HlyC,DUF21 MHFCBNDO_02344 543734.LCABL_24130 0.0 893.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 MHFCBNDO_02345 568703.LGG_02232 8.38e-80 240.0 2C9UQ@1|root,309VR@2|Bacteria,1U5T4@1239|Firmicutes,4IFH1@91061|Bacilli,3F6FU@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4811) - - - - - - - - - - - - DUF4811 MHFCBNDO_02346 543734.LCABL_24150 1.95e-127 362.0 COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli,3F65C@33958|Lactobacillaceae 91061|Bacilli D nucleoside-triphosphate diphosphatase activity maf GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K06287 - - - - ko00000 - - - Maf MHFCBNDO_02347 543734.LCABL_24160 0.0 1263.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,3F3PK@33958|Lactobacillaceae 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C MHFCBNDO_02348 543734.LCABL_24170 0.0 1654.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,3F4A5@33958|Lactobacillaceae 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V MHFCBNDO_02349 543734.LCABL_24180 0.0 1144.0 COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,4HAZH@91061|Bacilli,3F44Y@33958|Lactobacillaceae 91061|Bacilli E amino acid ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 MHFCBNDO_02350 543734.LCABL_24190 6.55e-75 225.0 2EUB0@1|root,33MTD@2|Bacteria,1W3MW@1239|Firmicutes,4HZUX@91061|Bacilli,3F7TK@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1827) - - - - - - - - - - - - DUF1827 MHFCBNDO_02351 568703.LGG_00464 4.64e-227 624.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_02352 543734.LCABL_24200 0.0 1016.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,3F3MM@33958|Lactobacillaceae 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 MHFCBNDO_02353 543734.LCABL_24210 1.7e-59 183.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,3F7CZ@33958|Lactobacillaceae 91061|Bacilli O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 MHFCBNDO_02354 543734.LCABL_24220 1.23e-142 403.0 COG1266@1|root,COG1266@2|Bacteria,1UZGJ@1239|Firmicutes,4HFCB@91061|Bacilli,3F5JU@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity ydiL - - ko:K07052 - - - - ko00000 - - - Abi MHFCBNDO_02355 543734.LCABL_24230 1.18e-250 688.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr MHFCBNDO_02356 543734.LCABL_24240 3.84e-235 648.0 2DKT0@1|root,30APV@2|Bacteria,1U6YM@1239|Firmicutes,4IGSU@91061|Bacilli,3F8QM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02357 543734.LCABL_24250 1.7e-203 564.0 COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,4HA3P@91061|Bacilli,3FC3A@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01990,ko:K16921 ko02010,map02010 M00254,M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_02358 543734.LCABL_24260 4.97e-81 240.0 COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,3F7AX@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR MHFCBNDO_02359 543734.LCABL_24270 1.1e-151 426.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,3F40G@33958|Lactobacillaceae 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N MHFCBNDO_02360 543734.LCABL_24280 0.0 1251.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,3F3QI@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn MHFCBNDO_02361 543734.LCABL_24290 3.12e-68 207.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F6GU@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit ptcB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB MHFCBNDO_02362 543734.LCABL_24300 5.99e-243 667.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,3F4AX@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 MHFCBNDO_02363 543734.LCABL_24310 8.44e-130 368.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,3F522@33958|Lactobacillaceae 91061|Bacilli K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 MHFCBNDO_02364 543734.LCABL_24320 3.82e-168 470.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,3F3WV@33958|Lactobacillaceae 91061|Bacilli O Universal bacterial protein YeaZ yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 MHFCBNDO_02365 1423732.BALS01000008_gene801 2.95e-96 285.0 2AQ5J@1|root,31FAY@2|Bacteria,1U7CF@1239|Firmicutes,4IH7T@91061|Bacilli,3F9CK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02366 543734.LCABL_24340 2.42e-117 336.0 COG3275@1|root,COG3275@2|Bacteria,1VB87@1239|Firmicutes,4ISET@91061|Bacilli,3FBSH@33958|Lactobacillaceae 91061|Bacilli T ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt MHFCBNDO_02367 543734.LCABL_24350 6.13e-232 638.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli,3F3XA@33958|Lactobacillaceae 91061|Bacilli EJ Asparaginase ansB - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase MHFCBNDO_02368 543734.LCABL_24360 3.86e-185 513.0 COG3884@1|root,COG3884@2|Bacteria,1V3RB@1239|Firmicutes,4HHJ4@91061|Bacilli,3F41B@33958|Lactobacillaceae 91061|Bacilli I Acyl-ACP thioesterase fat - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE MHFCBNDO_02369 543734.LCABL_24370 1.74e-191 533.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,3F4AI@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase MHFCBNDO_02370 543734.LCABL_24380 7.92e-76 226.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli,3F864@33958|Lactobacillaceae 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB MHFCBNDO_02371 543734.LCABL_24390 2.28e-223 617.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,3F50D@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C MHFCBNDO_02372 543734.LCABL_24400 1.14e-69 210.0 COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,3F6VW@33958|Lactobacillaceae 91061|Bacilli S Cyclic-di-AMP receptor yaaQ - - - - - - - - - - - CdAMP_rec MHFCBNDO_02373 543734.LCABL_24410 7.2e-151 424.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,3F4JR@33958|Lactobacillaceae 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin MHFCBNDO_02374 568703.LGG_02263 2.95e-46 149.0 2DKQT@1|root,30ADD@2|Bacteria,1U6HS@1239|Firmicutes,4IGA3@91061|Bacilli,3F7Y1@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2508) - - - - - - - - - - - - DUF2508 MHFCBNDO_02375 543734.LCABL_24430 1.26e-139 394.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,3F4JQ@33958|Lactobacillaceae 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 MHFCBNDO_02376 543734.LCABL_24440 7e-49 157.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,3F7F3@33958|Lactobacillaceae 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd MHFCBNDO_02377 543734.LCABL_24450 0.0 1097.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,3F3P2@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 MHFCBNDO_02378 543734.LCABL_24460 1.26e-117 336.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,3F6IS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam MHFCBNDO_02379 543734.LCABL_24470 9.05e-67 203.0 2EMDH@1|root,33F2E@2|Bacteria,1VKX3@1239|Firmicutes,4HR5Y@91061|Bacilli,3F709@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02380 543734.LCABL_24480 3.34e-139 393.0 COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HHCA@91061|Bacilli,3F4NU@33958|Lactobacillaceae 91061|Bacilli J Methyltransferase rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS MHFCBNDO_02381 543734.LCABL_24490 0.0 1676.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli,3F3PY@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504 2.A.1.3.37 - iYO844.BG12900 DUF2156,LPG_synthase_TM MHFCBNDO_02382 1423816.BACQ01000053_gene2052 1.15e-59 187.0 2BJY6@1|root,32EAT@2|Bacteria,1U7NB@1239|Firmicutes,4IHJK@91061|Bacilli,3F9XZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02383 543734.LCABL_24510 8.64e-225 619.0 COG1609@1|root,COG1609@2|Bacteria,1TQSQ@1239|Firmicutes,4HBNR@91061|Bacilli,3F4YI@33958|Lactobacillaceae 91061|Bacilli K lacI family ccpB - - - - - - - - - - - LacI,Peripla_BP_1 MHFCBNDO_02384 543734.LCABL_24520 0.0 3447.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,3F3M5@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase S8 family prtB - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLAP,fn3_5 MHFCBNDO_02385 543734.LCABL_24530 1.98e-204 566.0 COG0760@1|root,COG0760@2|Bacteria,1VT0K@1239|Firmicutes,4I4BP@91061|Bacilli,3F4RW@33958|Lactobacillaceae 91061|Bacilli M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins - - 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 MHFCBNDO_02386 543734.LCABL_24540 1.37e-74 224.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,3F6YA@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N MHFCBNDO_02387 543734.LCABL_24550 7.23e-108 311.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,3F4S4@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 MHFCBNDO_02388 543734.LCABL_24560 1.92e-283 776.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,3F3T5@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein mdtG - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr MHFCBNDO_02389 543734.LCABL_24570 6.03e-200 554.0 COG0454@1|root,COG0456@2|Bacteria,1V42X@1239|Firmicutes,4HI1M@91061|Bacilli,3F6TI@33958|Lactobacillaceae 91061|Bacilli K acetyltransferase - - - - - - - - - - - - - MHFCBNDO_02390 1423816.BACQ01000053_gene2060 4.02e-86 257.0 29Q17@1|root,30AZR@2|Bacteria,1U7BG@1239|Firmicutes,4IH6H@91061|Bacilli,3F99Z@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02391 543734.LCABL_24590 1.19e-277 760.0 COG2271@1|root,COG2271@2|Bacteria,1UHSG@1239|Firmicutes,4IS86@91061|Bacilli,3FBXF@33958|Lactobacillaceae 91061|Bacilli G Sugar (and other) transporter yceI - - ko:K08369 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr MHFCBNDO_02392 543734.LCABL_24600 0.0 903.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh MHFCBNDO_02393 543734.LCABL_24610 1.89e-158 444.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,3F3VQ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 MHFCBNDO_02394 543734.LCABL_24620 6.87e-93 271.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,3F64I@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N MHFCBNDO_02395 543734.LCABL_24630 0.0 1689.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HBQJ@91061|Bacilli,3F4E0@33958|Lactobacillaceae 91061|Bacilli P COG0474 Cation transport ATPase mgtA - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase MHFCBNDO_02396 543734.LCABL_24640 0.0 929.0 COG0154@1|root,COG0154@2|Bacteria,1TPGJ@1239|Firmicutes,4HBE7@91061|Bacilli,3F4UM@33958|Lactobacillaceae 91061|Bacilli J Belongs to the amidase family nylA - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase,Gram_pos_anchor MHFCBNDO_02397 543734.LCABL_24650 6.01e-87 255.0 COG5646@1|root,COG5646@2|Bacteria,1V6QT@1239|Firmicutes,4HIUI@91061|Bacilli,3F79K@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DU1801) frataxin - - ko:K05937 - - - - ko00000 - - - DUF1801 MHFCBNDO_02398 543734.LCABL_24660 5.08e-119 341.0 COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,4IS1C@91061|Bacilli,3FBQY@33958|Lactobacillaceae 91061|Bacilli S Cobalamin adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans MHFCBNDO_02399 543734.LCABL_24670 6.47e-124 354.0 COG4720@1|root,COG4720@2|Bacteria,1V5GD@1239|Firmicutes,4HI8Y@91061|Bacilli,3F5H7@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF-ribofla_trS,ECF_trnsprt MHFCBNDO_02400 543734.LCABL_24680 4.31e-83 246.0 2DNM7@1|root,32Y2X@2|Bacteria,1VF26@1239|Firmicutes,4HP82@91061|Bacilli,3F6AM@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4430) - - - - - - - - - - - - DUF4430 MHFCBNDO_02401 543734.LCABL_24690 0.0 1527.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,4HFF1@91061|Bacilli,3F3VU@33958|Lactobacillaceae 91061|Bacilli F ribonucleoside-triphosphate reductase activity rtpR - 1.17.4.2 ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02014,R02020,R02022,R02023,R04315 RC00013,RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC MHFCBNDO_02402 543734.LCABL_24700 3.77e-102 295.0 COG3613@1|root,COG3613@2|Bacteria,1U5KZ@1239|Firmicutes,4IFBV@91061|Bacilli,3F74G@33958|Lactobacillaceae 91061|Bacilli F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr MHFCBNDO_02403 543734.LCABL_24710 1.16e-203 563.0 COG4814@1|root,COG4814@2|Bacteria,1V910@1239|Firmicutes,4HF90@91061|Bacilli,3F4RX@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 MHFCBNDO_02404 543734.LCABL_24720 2.29e-130 370.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,3F55W@33958|Lactobacillaceae 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG MHFCBNDO_02405 543734.LCABL_24730 2.09e-30 107.0 COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4HR1W@91061|Bacilli,3F86Y@33958|Lactobacillaceae 91061|Bacilli U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE MHFCBNDO_02406 568703.LGG_02301 4.4e-29 103.0 COG0267@1|root,COG0267@2|Bacteria,1VFTQ@1239|Firmicutes,4HR5Q@91061|Bacilli,3F83F@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 MHFCBNDO_02407 543734.LCABL_24740 4.58e-220 608.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F3JM@33958|Lactobacillaceae 91061|Bacilli H 1,4-dihydroxy-2-naphthoate menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA MHFCBNDO_02408 543734.LCABL_24750 2.44e-216 598.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F6SN@33958|Lactobacillaceae 91061|Bacilli M UbiA prenyltransferase family menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA MHFCBNDO_02409 543734.LCABL_24760 2.2e-252 692.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HA6Y@91061|Bacilli,3FB4B@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE MHFCBNDO_02410 543734.LCABL_24770 6.86e-187 523.0 COG4939@1|root,COG4939@2|Bacteria,1V2YY@1239|Firmicutes,4HGMF@91061|Bacilli,3FBKH@33958|Lactobacillaceae 91061|Bacilli S FMN_bind cad - - ko:K20379 ko02024,map02024 - - - ko00000,ko00001 - - - FMN_bind MHFCBNDO_02411 543734.LCABL_24780 0.0 1251.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,3F4N1@33958|Lactobacillaceae 91061|Bacilli C NADH dehydrogenase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DoxX,Pyr_redox_2 MHFCBNDO_02412 543734.LCABL_24790 2.76e-104 301.0 COG5341@1|root,COG5341@2|Bacteria,1VCR8@1239|Firmicutes,4HMR5@91061|Bacilli,3F7R1@33958|Lactobacillaceae 91061|Bacilli S NusG domain II - - - - - - - - - - - - NusG_II MHFCBNDO_02413 543734.LCABL_24800 1.03e-127 364.0 COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,4HG1H@91061|Bacilli,3F3R8@33958|Lactobacillaceae 91061|Bacilli S Heptaprenyl diphosphate synthase component I hepA - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - Hpre_diP_synt_I MHFCBNDO_02414 543734.LCABL_24810 1.05e-228 630.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,3F4GC@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 - R09245,R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt MHFCBNDO_02416 543734.LCABL_24830 9.38e-158 442.0 COG2085@1|root,COG2085@2|Bacteria,1UXZM@1239|Firmicutes,4HDRH@91061|Bacilli,3FB9A@33958|Lactobacillaceae 91061|Bacilli S Rossmann-like domain - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored MHFCBNDO_02417 543734.LCABL_24840 6.03e-248 681.0 COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,3F4KZ@33958|Lactobacillaceae 91061|Bacilli C Luciferase-like monooxygenase XK27_00915 - - - - - - - - - - - Bac_luciferase MHFCBNDO_02418 568703.LGG_02318 1.65e-153 437.0 COG1131@1|root,COG1131@2|Bacteria,1TQA2@1239|Firmicutes,4HEU0@91061|Bacilli,3FC3N@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_02419 568703.LGG_02319 2.14e-219 614.0 28MM7@1|root,2ZAX4@2|Bacteria,1TT1Z@1239|Firmicutes,4HDYX@91061|Bacilli,3F45B@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02420 568703.LGG_02320 4.49e-186 526.0 28MJI@1|root,2ZAW0@2|Bacteria,1UZZX@1239|Firmicutes,4HCUA@91061|Bacilli,3F5KU@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - MHFCBNDO_02422 568703.LGG_02316 3.38e-95 286.0 2AGH5@1|root,316PQ@2|Bacteria,1U79G@1239|Firmicutes,4IH4B@91061|Bacilli,3F95I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02423 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_02424 568703.LGG_02316 2.29e-19 86.3 2AGH5@1|root,316PQ@2|Bacteria,1U79G@1239|Firmicutes,4IH4B@91061|Bacilli,3F95I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02425 543734.LCABL_24850 1.19e-125 357.0 COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli,3F5KC@33958|Lactobacillaceae 91061|Bacilli S YacP-like NYN domain yacP - - ko:K06962 - - - - ko00000 - - - NYN_YacP MHFCBNDO_02426 543734.LCABL_24860 2.21e-181 505.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,3F3TD@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind MHFCBNDO_02427 543734.LCABL_24870 4.83e-98 285.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,3F6HS@33958|Lactobacillaceae 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 MHFCBNDO_02428 543734.LCABL_24880 0.0 947.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,3F4K7@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g MHFCBNDO_02429 543734.LCABL_24890 0.0 909.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,3F4AD@33958|Lactobacillaceae 91061|Bacilli C FAD linked oxidases, C-terminal domain loxD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 MHFCBNDO_02430 543734.LCABL_24900 2.65e-139 393.0 29Q7Y@1|root,30B6Z@2|Bacteria,1U7NE@1239|Firmicutes,4IHJP@91061|Bacilli,3F9Y4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02432 543734.LCABL_24920 0.0 971.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,3F3PR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c MHFCBNDO_02433 543734.LCABL_24930 4.9e-239 656.0 COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,4HAPJ@91061|Bacilli,3F4XH@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold XK27_10475 - - - - - - - - - - - GFO_IDH_MocA MHFCBNDO_02434 543734.LCABL_24940 1.01e-150 424.0 COG0120@1|root,COG0120@2|Bacteria,1W0HS@1239|Firmicutes,4HZEY@91061|Bacilli,3F757@33958|Lactobacillaceae 91061|Bacilli G Ribose 5-phosphate isomerase A (phosphoriboisomerase A) rpiA1 - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A MHFCBNDO_02435 543734.LCABL_24950 1.73e-182 509.0 COG1737@1|root,COG1737@2|Bacteria,1UYAM@1239|Firmicutes,4HVUK@91061|Bacilli,3FC4F@33958|Lactobacillaceae 91061|Bacilli K SIS domain - - - - - - - - - - - - HTH_6,SIS MHFCBNDO_02436 543734.LCABL_24960 2.26e-146 416.0 COG4377@1|root,COG4377@2|Bacteria,1V3UF@1239|Firmicutes,4HEYB@91061|Bacilli,3F7XI@33958|Lactobacillaceae 91061|Bacilli S Putative membrane peptidase family (DUF2324) yhfC - - - - - - - - - - - DUF2324 MHFCBNDO_02437 543734.LCABL_24980 1.37e-226 626.0 COG4194@1|root,COG4194@2|Bacteria,1UY2R@1239|Firmicutes,4HEEQ@91061|Bacilli,3F7N8@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - DUF1648 MHFCBNDO_02438 543734.LCABL_24990 5.31e-82 243.0 COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,4HJDB@91061|Bacilli,3F8MP@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - GntR MHFCBNDO_02439 543734.LCABL_25040 1.17e-286 785.0 COG4932@1|root,COG4932@2|Bacteria,1UWF2@1239|Firmicutes,4HGU0@91061|Bacilli,3F6D1@33958|Lactobacillaceae 91061|Bacilli M MucBP domain inlJ - - - - - - - - - - - DUF285,Gram_pos_anchor,MucBP MHFCBNDO_02440 1423816.BACQ01000056_gene2171 6.64e-243 699.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli,3F3QF@33958|Lactobacillaceae 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 MHFCBNDO_02441 543734.LCABL_25050 3.13e-97 292.0 COG1277@1|root,COG1277@2|Bacteria,1V1GX@1239|Firmicutes,4HG2P@91061|Bacilli,3F52P@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4 MHFCBNDO_02442 543734.LCABL_25060 1.25e-135 392.0 COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,3F3YW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_02443 543734.LCABL_25070 1.45e-148 425.0 COG1396@1|root,COG1396@2|Bacteria,1U7HF@1239|Firmicutes,4IHE2@91061|Bacilli,3F9PR@33958|Lactobacillaceae 91061|Bacilli K sequence-specific DNA binding - - - - - - - - - - - - - MHFCBNDO_02444 543734.LCABL_25080 5.49e-261 716.0 COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,3F46T@33958|Lactobacillaceae 91061|Bacilli S domain protein yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - TRAM MHFCBNDO_02445 543734.LCABL_25090 0.0 877.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,3F3W8@33958|Lactobacillaceae 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI MHFCBNDO_02446 543734.LCABL_25100 4.85e-130 369.0 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli,3FB45@33958|Lactobacillaceae 91061|Bacilli F dUTPase dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase MHFCBNDO_02447 543734.LCABL_25110 1.22e-67 204.0 COG2388@1|root,COG2388@2|Bacteria,1VEEX@1239|Firmicutes,4HNR2@91061|Bacilli,3F80F@33958|Lactobacillaceae 91061|Bacilli S GCN5-related N-acetyl-transferase yjdJ - - ko:K06975 - - - - ko00000 - - - Acetyltransf_CG MHFCBNDO_02448 543734.LCABL_25120 5.93e-93 270.0 COG3152@1|root,COG3152@2|Bacteria,1VZ1N@1239|Firmicutes,4HY6Y@91061|Bacilli,3FCFB@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 MHFCBNDO_02449 543734.LCABL_25130 0.0 886.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F3QA@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepE - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 MHFCBNDO_02450 543734.LCABL_25140 0.0 901.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F49B@33958|Lactobacillaceae 91061|Bacilli E Peptidase C1-like family pepC - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 MHFCBNDO_02451 543734.LCABL_25150 1.09e-253 697.0 28MJI@1|root,2ZAW0@2|Bacteria,1UZZX@1239|Firmicutes,4HCUA@91061|Bacilli,3F5KU@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - MHFCBNDO_02452 543734.LCABL_25160 2.48e-275 754.0 28MM7@1|root,2Z8B9@2|Bacteria,1UJ2G@1239|Firmicutes,4ISZP@91061|Bacilli,3FBU3@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - MHFCBNDO_02453 543734.LCABL_25170 5.79e-214 590.0 COG1131@1|root,COG1131@2|Bacteria,1TQA2@1239|Firmicutes,4HEU0@91061|Bacilli,3FC3N@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_02454 543734.LCABL_25180 0.0 1332.0 COG3158@1|root,COG3158@2|Bacteria,1TRUQ@1239|Firmicutes,4HA8Z@91061|Bacilli,3F4CU@33958|Lactobacillaceae 91061|Bacilli P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans MHFCBNDO_02455 543734.LCABL_25190 0.0 1696.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4HBU2@91061|Bacilli,3FBUR@33958|Lactobacillaceae 91061|Bacilli G Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N MHFCBNDO_02456 543734.LCABL_25200 8.84e-120 344.0 COG0517@1|root,COG0517@2|Bacteria,1TRZD@1239|Firmicutes,4HC4C@91061|Bacilli,3F6K8@33958|Lactobacillaceae 91061|Bacilli K Domain in cystathionine beta-synthase and other proteins. ccpN GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - CBS,HTH_11 MHFCBNDO_02457 543734.LCABL_25210 2.41e-158 444.0 COG0588@1|root,COG0588@2|Bacteria,1V2UT@1239|Firmicutes,4HGRK@91061|Bacilli,3F443@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA1 - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 MHFCBNDO_02458 543734.LCABL_25220 9.51e-263 720.0 COG4292@1|root,COG4292@2|Bacteria,1VAA8@1239|Firmicutes,4IRU7@91061|Bacilli,3FBQ1@33958|Lactobacillaceae 91061|Bacilli S Bacterial low temperature requirement A protein (LtrA) - - - - - - - - - - - - LtrA MHFCBNDO_02459 543734.LCABL_25230 5.25e-61 187.0 294CX@1|root,2ZRSX@2|Bacteria,1W32Y@1239|Firmicutes,4I1C7@91061|Bacilli,3F85H@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02460 543734.LCABL_25240 1.64e-262 719.0 COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,4HAU5@91061|Bacilli,3F3N3@33958|Lactobacillaceae 91061|Bacilli C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases lctO - 1.13.12.4 ko:K00467,ko:K10530 ko00620,map00620 - R00319 RC01312 ko00000,ko00001,ko01000 - - - FMN_dh MHFCBNDO_02461 543734.LCABL_25250 1.59e-28 103.0 COG3237@1|root,COG3237@2|Bacteria 2|Bacteria K CsbD-like yhjA - - - - - - - - - - - CsbD MHFCBNDO_02463 543734.LCABL_25320 1.5e-44 144.0 29PRZ@1|root,30AQ7@2|Bacteria,1U6Z6@1239|Firmicutes,4IGTF@91061|Bacilli,3F8RC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02464 543734.LCABL_25330 5.02e-52 164.0 2DKSV@1|root,30APG@2|Bacteria,1U6Y5@1239|Firmicutes,4IGSB@91061|Bacilli,3F8PU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02465 543734.LCABL_25340 8.53e-287 784.0 COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,4HFIF@91061|Bacilli,3F5PJ@33958|Lactobacillaceae 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 MHFCBNDO_02466 543734.LCABL_25350 2.21e-277 761.0 COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli,3F3W7@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13130 Aldedh MHFCBNDO_02467 543734.LCABL_25360 6.34e-190 528.0 COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli,3F4E1@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase MHFCBNDO_02469 1423732.BALS01000031_gene63 3.64e-55 179.0 29Q5T@1|root,30B4Q@2|Bacteria,1U7IZ@1239|Firmicutes,4IHFS@91061|Bacilli,3F9SF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02470 543734.LCABL_25380 9.34e-294 801.0 COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,4HITC@91061|Bacilli,3F50M@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - MHFCBNDO_02471 543734.LCABL_25390 1.05e-187 522.0 COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,4HG4C@91061|Bacilli,3FCAD@33958|Lactobacillaceae 91061|Bacilli M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase MHFCBNDO_02472 543734.LCABL_25400 0.0 1020.0 COG4932@1|root,COG4932@2|Bacteria,1UY9B@1239|Firmicutes,4HW31@91061|Bacilli,3F6KV@33958|Lactobacillaceae 91061|Bacilli M Cna protein B-type domain - - - - - - - - - - - - GramPos_pilinD1 MHFCBNDO_02473 543734.LCABL_25410 1.01e-307 840.0 2EZ87@1|root,33SE3@2|Bacteria,1UM06@1239|Firmicutes,4ITNG@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02474 543734.LCABL_25420 0.0 1952.0 COG4932@1|root,COG4932@2|Bacteria,1VRZM@1239|Firmicutes,4HTFC@91061|Bacilli,3F8GT@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - - MHFCBNDO_02475 1423816.BACQ01000072_gene2585 1.05e-131 373.0 2AYWY@1|root,31R2N@2|Bacteria,1UPXG@1239|Firmicutes,4IVCM@91061|Bacilli,3F66A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02476 543734.LCABL_25440 4.42e-292 796.0 COG3410@1|root,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,4HBI0@91061|Bacilli,3F47M@33958|Lactobacillaceae 91061|Bacilli N Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075,GIY-YIG MHFCBNDO_02477 543734.LCABL_25450 4.01e-262 717.0 COG1073@1|root,COG1073@2|Bacteria,1UF81@1239|Firmicutes,4HI1Q@91061|Bacilli,3FBVJ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 MHFCBNDO_02478 543734.LCABL_25460 2.81e-99 293.0 COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,4HH0D@91061|Bacilli,3F84P@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 MHFCBNDO_02479 543734.LCABL_25470 2.05e-72 217.0 COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,4HKBS@91061|Bacilli,3F7N2@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family padR - - ko:K10947 - - - - ko00000,ko03000 - - - PadR MHFCBNDO_02480 568703.LGG_02378 6.77e-81 251.0 2AG9B@1|root,30AYZ@2|Bacteria,1U7AB@1239|Firmicutes,4IH59@91061|Bacilli,3F976@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02481 543734.LCABL_25490 1.22e-175 491.0 2AG9B@1|root,30AYZ@2|Bacteria,1U7AB@1239|Firmicutes,4IH59@91061|Bacilli,3F976@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02482 543734.LCABL_25500 6.69e-61 187.0 2DEZ9@1|root,2ZPV3@2|Bacteria,1W247@1239|Firmicutes,4I0IP@91061|Bacilli,3F8UH@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun MHFCBNDO_02483 543734.LCABL_25510 2.22e-60 186.0 2DEZ9@1|root,2ZPV3@2|Bacteria,1W247@1239|Firmicutes,4I0IP@91061|Bacilli 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun MHFCBNDO_02484 543734.LCABL_25520 4.94e-59 182.0 COG1476@1|root,COG1476@2|Bacteria,1UM07@1239|Firmicutes,4ITNH@91061|Bacilli,3F86R@33958|Lactobacillaceae 91061|Bacilli K TRANSCRIPTIONal spiA - - - - - - - - - - - EntA_Immun MHFCBNDO_02485 543734.LCABL_25530 0.0 874.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,4HU4D@91061|Bacilli,3F4FR@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE,ThrE_2 MHFCBNDO_02487 543734.LCABL_25560 5.75e-72 216.0 2BTF9@1|root,32NMI@2|Bacteria,1U8E8@1239|Firmicutes,4IIC5@91061|Bacilli,3FAW0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02488 543734.LCABL_25570 6.57e-309 844.0 COG0845@1|root,COG0845@2|Bacteria,1V5C8@1239|Firmicutes,4HHKB@91061|Bacilli,3F5W4@33958|Lactobacillaceae 91061|Bacilli M Transport protein ComB mesE - - ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko02000 3.A.1.112,8.A.1,8.A.1.4.2 - - HlyD_3 MHFCBNDO_02489 1423816.BACQ01000056_gene2171 0.0 1286.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli,3F3QF@33958|Lactobacillaceae 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 MHFCBNDO_02491 543734.LCABL_25610 2.1e-173 493.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity - - 2.7.13.3 ko:K02476,ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 MHFCBNDO_02492 543734.LCABL_25620 7.99e-184 512.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,3F3VI@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain plnD - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg MHFCBNDO_02494 568703.LGG_02391 1.62e-12 62.4 2AIQB@1|root,31972@2|Bacteria,1U866@1239|Firmicutes,4II3R@91061|Bacilli,3FAKI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02498 543734.LCABL_25670 9.93e-182 507.0 COG1266@1|root,COG1266@2|Bacteria,1W74D@1239|Firmicutes,4HXYG@91061|Bacilli,3F80E@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi MHFCBNDO_02499 543734.LCABL_25690 2.29e-74 222.0 29PYM@1|root,30AX3@2|Bacteria,1U77W@1239|Firmicutes,4IH2P@91061|Bacilli,3F935@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02501 543734.LCABL_25720 1.18e-72 218.0 2CCCW@1|root,2ZFAQ@2|Bacteria,1W39Y@1239|Firmicutes,4I054@91061|Bacilli,3F8D6@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun MHFCBNDO_02502 543734.LCABL_25730 7.86e-138 390.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,3F59K@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac MHFCBNDO_02506 543734.LCABL_25770 8.37e-231 635.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,3F4U1@33958|Lactobacillaceae 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red MHFCBNDO_02507 543734.LCABL_25780 3.51e-166 465.0 COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,3F468@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short MHFCBNDO_02508 543734.LCABL_25790 4.77e-270 740.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,3F3UQ@33958|Lactobacillaceae 91061|Bacilli C Oxidoreductase yqiG - - - - - - - - - - - Oxidored_FMN MHFCBNDO_02509 543734.LCABL_25800 0.0 874.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,3F3K0@33958|Lactobacillaceae 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 MHFCBNDO_02510 543734.LCABL_25810 2.2e-173 484.0 29Q1N@1|root,30B08@2|Bacteria,1U7C1@1239|Firmicutes,4IH7B@91061|Bacilli,3F9BP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02511 543734.LCABL_25820 5.81e-22 85.1 2BSE3@1|root,32MG2@2|Bacteria,1U8AV@1239|Firmicutes,4II8V@91061|Bacilli,3FASA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02512 543734.LCABL_25830 0.0 946.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp MHFCBNDO_02513 543734.LCABL_25840 0.0 1708.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase atp2C1 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 MHFCBNDO_02514 1423732.BALS01000064_gene2233 1.14e-72 219.0 29PE3@1|root,32D7A@2|Bacteria,1U7IM@1239|Firmicutes,4IHFA@91061|Bacilli,3F9RV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02515 543734.LCABL_25860 3.62e-305 835.0 COG0477@1|root,COG0477@2|Bacteria,1UJ8F@1239|Firmicutes,4IT4C@91061|Bacilli,3FBUG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_5 MHFCBNDO_02516 543734.LCABL_25870 0.0 1075.0 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli,3F3XB@33958|Lactobacillaceae 91061|Bacilli Q Multicopper oxidase sufI - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 MHFCBNDO_02517 543734.LCABL_25880 1.53e-35 120.0 2FB4N@1|root,343B1@2|Bacteria,1VZEN@1239|Firmicutes,4HYPA@91061|Bacilli,3F944@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02518 543734.LCABL_25890 2.22e-144 407.0 COG0053@1|root,COG0053@2|Bacteria,1V9B6@1239|Firmicutes,4HJTJ@91061|Bacilli,3F4M1@33958|Lactobacillaceae 91061|Bacilli P Cation efflux family - - - - - - - - - - - - Cation_efflux MHFCBNDO_02519 543734.LCABL_25900 1.23e-69 210.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,3F7DH@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, ArsR family czrA - - ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 MHFCBNDO_02520 543734.LCABL_25920 6.58e-226 622.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli,3F4B9@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family mntA - - ko:K19975,ko:K19976 ko02010,map02010 M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.15 - - ZnuA MHFCBNDO_02521 543734.LCABL_25930 5.89e-185 517.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli,3F4JM@33958|Lactobacillaceae 91061|Bacilli U ABC 3 transport family mtsB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K19972,ko:K19976 ko02010,map02010 M00791,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.14,3.A.1.15.15,3.A.1.15.2 - - ABC-3 MHFCBNDO_02522 543734.LCABL_25940 3.38e-170 476.0 COG1121@1|root,COG1121@2|Bacteria,1UM08@1239|Firmicutes 1239|Firmicutes P AAA domain, putative AbiEii toxin, Type IV TA system - - 3.6.3.35 ko:K19973 ko02010,map02010 M00792 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.15 - - ABC_tran MHFCBNDO_02523 543734.LCABL_25950 0.0 952.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family aldA - 1.2.1.21,1.2.1.22 ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 - R00203,R01333,R01446 RC00080,RC00104,RC00242 ko00000,ko00001,ko01000 - - - Aldedh MHFCBNDO_02524 543734.LCABL_25960 6.85e-55 171.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HKK1@91061|Bacilli,3F7KX@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 MHFCBNDO_02525 334390.LAF_0675 2.45e-245 673.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve MHFCBNDO_02526 543734.LCABL_25990 6.75e-215 593.0 COG0803@1|root,COG0803@2|Bacteria,1V110@1239|Firmicutes,4HZ7G@91061|Bacilli,3FBJR@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family psaA - - ko:K02077,ko:K11707 ko02010,map02010 M00244,M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA MHFCBNDO_02527 543734.LCABL_26000 2.83e-152 427.0 COG0702@1|root,COG0702@2|Bacteria,1UJSC@1239|Firmicutes,4HCVT@91061|Bacilli,3F4ZZ@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 MHFCBNDO_02528 543734.LCABL_26010 8.09e-146 411.0 COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,4HHQT@91061|Bacilli,3F4BS@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain yjhB - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,Nudix_N MHFCBNDO_02529 543734.LCABL_26020 1.17e-100 294.0 29Q79@1|root,30B6A@2|Bacteria,1U7MC@1239|Firmicutes,4IHIH@91061|Bacilli,3F9WH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02530 543734.LCABL_26030 0.0 901.0 COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,3F4FM@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - Cna_B,Collagen_bind,Gram_pos_anchor MHFCBNDO_02531 543734.LCABL_26040 1.26e-212 587.0 COG0803@1|root,COG0803@2|Bacteria,1V110@1239|Firmicutes,4HZ7G@91061|Bacilli,3FBJR@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family psaA - - ko:K02077,ko:K11707 ko02010,map02010 M00244,M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA MHFCBNDO_02532 543734.LCABL_26060 2.1e-27 99.4 29QM9@1|root,30BKW@2|Bacteria,1U8AT@1239|Firmicutes,4II8S@91061|Bacilli,3FAS5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02535 1423816.BACQ01000060_gene2301 1.86e-155 483.0 2ED61@1|root,3372S@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - MHFCBNDO_02539 543734.LCABL_26100 3.56e-68 207.0 COG0239@1|root,COG0239@2|Bacteria,1VM30@1239|Firmicutes,4HRC4@91061|Bacilli,3F8A8@33958|Lactobacillaceae 91061|Bacilli U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB MHFCBNDO_02540 543734.LCABL_26110 7.54e-90 263.0 COG0239@1|root,COG0239@2|Bacteria,1U4G6@1239|Firmicutes,4IE88@91061|Bacilli,3F6R4@33958|Lactobacillaceae 91061|Bacilli U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB1 - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB MHFCBNDO_02543 1423734.JCM14202_2530 1.51e-280 770.0 COG0148@1|root,COG0148@2|Bacteria,1V12I@1239|Firmicutes,4HTD2@91061|Bacilli,3FCCA@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0043236,GO:0050840 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N MHFCBNDO_02544 1114972.AUAW01000012_gene1149 3.3e-284 806.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HVA4@91061|Bacilli,3F55J@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus - - - - - - - - - - - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase MHFCBNDO_02545 543734.LCABL_26140 1.99e-212 588.0 COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,3F3KK@33958|Lactobacillaceae 91061|Bacilli P Phosphonate ABC transporter phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd MHFCBNDO_02546 543734.LCABL_26150 6.08e-178 496.0 COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,4HC3N@91061|Bacilli,3F3SJ@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC GO:0006810,GO:0008150,GO:0015716,GO:0051179,GO:0051234,GO:0071702 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran MHFCBNDO_02547 543734.LCABL_26160 1e-173 486.0 COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,4HBT8@91061|Bacilli,3F58M@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component phnB - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 MHFCBNDO_02548 543734.LCABL_26170 3.27e-187 520.0 COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,4HBI5@91061|Bacilli,3FBJQ@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component ptxC - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 MHFCBNDO_02549 543734.LCABL_26190 7.07e-100 296.0 COG0715@1|root,COG0715@2|Bacteria,1TPI2@1239|Firmicutes,4HDP6@91061|Bacilli,3F4DK@33958|Lactobacillaceae 91061|Bacilli P NMT1-like family ssuA - - ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - NMT1,NMT1_2 MHFCBNDO_02550 543734.LCABL_26190 4.18e-103 305.0 COG0715@1|root,COG0715@2|Bacteria,1TPI2@1239|Firmicutes,4HDP6@91061|Bacilli,3F4DK@33958|Lactobacillaceae 91061|Bacilli P NMT1-like family ssuA - - ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - NMT1,NMT1_2 MHFCBNDO_02551 543734.LCABL_26200 0.0 1007.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,3FC48@33958|Lactobacillaceae 91061|Bacilli IQ AMP-binding enzyme C-terminal domain - - 6.2.1.48 ko:K02182 - - - - ko00000,ko01000 - - - AMP-binding,AMP-binding_C MHFCBNDO_02552 543734.LCABL_26210 2.71e-299 816.0 COG1835@1|root,COG1835@2|Bacteria,1V8A9@1239|Firmicutes,4HJ67@91061|Bacilli,3F5JA@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 MHFCBNDO_02553 543734.LCABL_26220 1.17e-154 435.0 COG1116@1|root,COG1116@2|Bacteria,1TRE2@1239|Firmicutes,4HAHM@91061|Bacilli,3F5YE@33958|Lactobacillaceae 91061|Bacilli P ATPases associated with a variety of cellular activities ssuB - - ko:K15555 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.17.2 - - ABC_tran MHFCBNDO_02554 543734.LCABL_26230 2.8e-190 528.0 COG0600@1|root,COG0600@2|Bacteria,1TQ26@1239|Firmicutes,4HCJ7@91061|Bacilli,3F4W8@33958|Lactobacillaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component ssuC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0042908,GO:0042910,GO:0042918,GO:0042959,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K15554 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.2 - - BPD_transp_1 MHFCBNDO_02555 543734.LCABL_26240 2.27e-174 487.0 COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,4HDII@91061|Bacilli,3F5Q6@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein XK27_06950 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 MHFCBNDO_02556 543734.LCABL_26250 3.49e-172 481.0 COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,4HFPQ@91061|Bacilli,3F66B@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein XK27_06945 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 MHFCBNDO_02557 543734.LCABL_26260 2.47e-169 477.0 COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,3F5QG@33958|Lactobacillaceae 91061|Bacilli S ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_02558 568703.LGG_00380 1.48e-40 143.0 299D6@1|root,2ZWG2@2|Bacteria,1V564@1239|Firmicutes,4HI66@91061|Bacilli,3F6SE@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 MHFCBNDO_02559 543734.LCABL_26300 3.73e-126 370.0 2BQ3C@1|root,32IXT@2|Bacteria,1U82X@1239|Firmicutes,4II0B@91061|Bacilli,3FAGQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02560 543734.LCABL_26310 6.17e-73 218.0 2E9Y3@1|root,32JRV@2|Bacteria,1TVPM@1239|Firmicutes,4I3SR@91061|Bacilli,3FA3I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02561 543734.LCABL_26320 8.98e-86 253.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,3F656@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 MHFCBNDO_02562 543734.LCABL_26330 2.98e-104 301.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,3F696@33958|Lactobacillaceae 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 MHFCBNDO_02563 543734.LCABL_26340 1.99e-138 392.0 COG1309@1|root,COG1309@2|Bacteria,1VD4H@1239|Firmicutes,4HNBF@91061|Bacilli,3F5VC@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N MHFCBNDO_02564 543734.LCABL_26350 2.05e-235 649.0 COG0577@1|root,COG0577@2|Bacteria,1TVQ4@1239|Firmicutes,4IRU4@91061|Bacilli,3FBQ0@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX MHFCBNDO_02565 543734.LCABL_26360 1.01e-161 453.0 COG1136@1|root,COG1136@2|Bacteria,1UYJ6@1239|Firmicutes,4HF89@91061|Bacilli,3F5SR@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_02566 1423732.BALS01000005_gene1101 1.5e-44 144.0 29PH8@1|root,30AFD@2|Bacteria,1U6KC@1239|Firmicutes,4IGD6@91061|Bacilli,3F83D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02567 543734.LCABL_26380 2.18e-169 474.0 COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,4HUDT@91061|Bacilli,3FC68@33958|Lactobacillaceae 91061|Bacilli K TipAS antibiotic-recognition domain tipA - - - - - - - - - - - MerR_1,TipAS MHFCBNDO_02568 565653.EGBG_00234 2.97e-27 114.0 COG4858@1|root,COG4858@2|Bacteria,1V9IF@1239|Firmicutes,4HKB8@91061|Bacilli,4B352@81852|Enterococcaceae 91061|Bacilli - - ORF00048 - - - - - - - - - - - DUF1129 MHFCBNDO_02569 1136177.KCA1_2522 1.2e-42 142.0 COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,4HKBS@91061|Bacilli,3F70B@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family padR - - ko:K10947 - - - - ko00000,ko03000 - - - PadR MHFCBNDO_02570 543734.LCABL_26390 6.62e-177 493.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,3F4KC@33958|Lactobacillaceae 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 MHFCBNDO_02571 543734.LCABL_26400 4.62e-181 504.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,3F3UW@33958|Lactobacillaceae 91061|Bacilli U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ MHFCBNDO_02572 543734.LCABL_26410 1.92e-202 560.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,3F48E@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran MHFCBNDO_02573 543734.LCABL_26420 1.15e-197 548.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,3F3VD@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran MHFCBNDO_02574 543734.LCABL_26430 2.48e-151 426.0 2BKGG@1|root,32EXB@2|Bacteria,1U7Q7@1239|Firmicutes,4IHMI@91061|Bacilli,3FA0B@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02575 543734.LCABL_26440 5.46e-81 240.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli,3F6GJ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 MHFCBNDO_02576 543734.LCABL_26450 1.26e-218 603.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,3F3W6@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L MHFCBNDO_02577 543734.LCABL_26460 3.82e-82 243.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,3F67D@33958|Lactobacillaceae 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 MHFCBNDO_02578 543734.LCABL_26470 3.11e-75 225.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,3F6GN@33958|Lactobacillaceae 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 MHFCBNDO_02579 543734.LCABL_26480 6.38e-20 79.7 COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4HR2X@91061|Bacilli,3F8TC@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 MHFCBNDO_02580 543734.LCABL_26490 4.15e-46 148.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,3F7CW@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a MHFCBNDO_02581 543734.LCABL_26500 1.29e-155 436.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,3F3KB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid MHFCBNDO_02582 543734.LCABL_26510 2.01e-303 829.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,3F4FV@33958|Lactobacillaceae 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY MHFCBNDO_02583 543734.LCABL_26520 4.07e-92 270.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,3F675@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A MHFCBNDO_02584 543734.LCABL_26530 2.6e-33 115.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli,3F7ZU@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 MHFCBNDO_02585 543734.LCABL_26540 5.74e-109 314.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,3F3VY@33958|Lactobacillaceae 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C MHFCBNDO_02586 543734.LCABL_26550 1.62e-76 228.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,3F6KN@33958|Lactobacillaceae 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p MHFCBNDO_02587 543734.LCABL_26560 2.61e-123 351.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,3F4G5@33958|Lactobacillaceae 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 MHFCBNDO_02588 543734.LCABL_26570 1.32e-88 260.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,3F64E@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 MHFCBNDO_02589 1423816.BACQ01000060_gene2284 8.67e-124 353.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,3F3Q7@33958|Lactobacillaceae 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C MHFCBNDO_02590 543734.LCABL_26590 4.1e-67 203.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,3F6X5@33958|Lactobacillaceae 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 MHFCBNDO_02591 543734.LCABL_26600 1.73e-77 231.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli,3F6GT@33958|Lactobacillaceae 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 MHFCBNDO_02592 543734.LCABL_26610 5.93e-55 171.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,3F7FX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 MHFCBNDO_02593 543734.LCABL_26620 3.55e-33 115.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,3F82Z@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 MHFCBNDO_02594 543734.LCABL_26630 1.38e-98 286.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,3F653@33958|Lactobacillaceae 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 MHFCBNDO_02595 543734.LCABL_26640 6.88e-152 427.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,3F3Q8@33958|Lactobacillaceae 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C MHFCBNDO_02596 1423732.BALS01000005_gene1074 4.5e-73 219.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,3F6K6@33958|Lactobacillaceae 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 MHFCBNDO_02597 1423732.BALS01000005_gene1073 5.26e-63 192.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,3F6XP@33958|Lactobacillaceae 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 MHFCBNDO_02598 543734.LCABL_26670 7.23e-201 556.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,3F3XI@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C MHFCBNDO_02599 543734.LCABL_26680 1.02e-61 189.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli,3F6Z2@33958|Lactobacillaceae 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 MHFCBNDO_02600 543734.LCABL_26690 1.98e-140 397.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,3F3QD@33958|Lactobacillaceae 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 MHFCBNDO_02601 543734.LCABL_26700 4.01e-146 412.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli,3F45I@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 MHFCBNDO_02602 543734.LCABL_26710 4.46e-66 201.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,3F6KC@33958|Lactobacillaceae 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 MHFCBNDO_02603 543734.LCABL_26720 2.1e-89 263.0 COG3223@1|root,COG3223@2|Bacteria,1V9CG@1239|Firmicutes,4HIMW@91061|Bacilli 91061|Bacilli S Phosphate-starvation-inducible E psiE - - ko:K13256 - - - - ko00000 - - - PsiE MHFCBNDO_02604 543734.LCABL_26730 3.96e-137 387.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HVUV@91061|Bacilli,3FCCT@33958|Lactobacillaceae 91061|Bacilli O C-terminal domain of 1-Cys peroxiredoxin ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA MHFCBNDO_02605 543734.LCABL_26740 2.68e-252 691.0 COG2378@1|root,COG2378@2|Bacteria,1VVQ0@1239|Firmicutes,4HW20@91061|Bacilli,3FB7T@33958|Lactobacillaceae 91061|Bacilli K WYL domain - - - - - - - - - - - - WYL MHFCBNDO_02606 543734.LCABL_26750 0.0 1377.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,3F3JR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 MHFCBNDO_02607 1423732.BALS01000083_gene2031 2.06e-108 312.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,3F3RX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 MHFCBNDO_02608 543734.LCABL_26770 1.11e-92 271.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli,3F64B@33958|Lactobacillaceae 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 MHFCBNDO_02609 543734.LCABL_26780 0.0 5116.0 COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,3F7WQ@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - Cna_B,Collagen_bind,FctA,Gram_pos_anchor MHFCBNDO_02610 1423816.BACQ01000061_gene2309 1.27e-47 159.0 29Q94@1|root,30B88@2|Bacteria,1U7QC@1239|Firmicutes,4IHMP@91061|Bacilli,3FA0H@33958|Lactobacillaceae 91061|Bacilli - - - - 3.4.23.43 ko:K02236 - M00429 - - ko00000,ko00002,ko01000,ko02044 - - - - MHFCBNDO_02611 543734.LCABL_26800 0.0 2407.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,3F3KF@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 MHFCBNDO_02612 543734.LCABL_26820 0.0 2353.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,3F4ET@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 MHFCBNDO_02613 543734.LCABL_26830 0.0 1601.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3F3RV@33958|Lactobacillaceae 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR MHFCBNDO_02614 543734.LCABL_26840 4.32e-105 303.0 COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli,3F53E@33958|Lactobacillaceae 91061|Bacilli K Belongs to the CtsR family ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03708 - - - - ko00000,ko03000 - - - CtsR MHFCBNDO_02624 568703.LGG_00307 5.19e-90 263.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - MHFCBNDO_02627 543734.LCABL_26990 0.0 1003.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,3F439@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon MHFCBNDO_02628 543734.LCABL_27000 4.37e-241 662.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,3F4C6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus MHFCBNDO_02629 543734.LCABL_27010 4.2e-208 575.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,3F42B@33958|Lactobacillaceae 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 MHFCBNDO_02630 543734.LCABL_27020 8.79e-208 575.0 29Q36@1|root,30B1U@2|Bacteria,1U7E3@1239|Firmicutes,4IH9Z@91061|Bacilli,3F9G9@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL MHFCBNDO_02631 543734.LCABL_27040 2.27e-241 665.0 COG4072@1|root,COG4072@2|Bacteria,1U765@1239|Firmicutes,4IH0X@91061|Bacilli,3F910@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF916) - - - - - - - - - - - - DUF3324,DUF916 MHFCBNDO_02632 543734.LCABL_27050 2.28e-248 681.0 COG4072@1|root,COG4072@2|Bacteria,1V92G@1239|Firmicutes,4HIJ2@91061|Bacilli,3F9EF@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function C-terminal (DUF3324) - - - - - - - - - - - - DUF3324,DUF916 MHFCBNDO_02633 543734.LCABL_27060 0.0 1652.0 COG4886@1|root,COG4886@2|Bacteria,1VUWY@1239|Firmicutes,4HVSW@91061|Bacilli,3F94G@33958|Lactobacillaceae 91061|Bacilli S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - MHFCBNDO_02634 543734.LCABL_27070 0.0 1273.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,3F49Z@33958|Lactobacillaceae 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 MHFCBNDO_02635 543734.LCABL_27080 1.14e-124 355.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,3F56C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran MHFCBNDO_02636 543734.LCABL_27090 7.68e-310 845.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,3F4GY@33958|Lactobacillaceae 91061|Bacilli J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C MHFCBNDO_02637 543734.LCABL_27100 1.17e-105 305.0 COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,3F6HV@33958|Lactobacillaceae 91061|Bacilli J RNA binding yabR - - ko:K07571 - - - - ko00000 - - - S1 MHFCBNDO_02638 543734.LCABL_27110 7.17e-87 256.0 COG2919@1|root,COG2919@2|Bacteria 2|Bacteria D cell cycle divIC - - ko:K05589,ko:K13052 - - - - ko00000,ko03036 - - - DivIC MHFCBNDO_02639 543734.LCABL_27120 1.99e-53 167.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,3F7JX@33958|Lactobacillaceae 91061|Bacilli J S4 domain protein yabO - - - - - - - - - - - S4 MHFCBNDO_02640 543734.LCABL_27130 0.0 971.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HACG@91061|Bacilli,3F4BV@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C MHFCBNDO_02641 543734.LCABL_27140 0.0 2267.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,3F4KU@33958|Lactobacillaceae 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF MHFCBNDO_02642 543734.LCABL_27150 4.28e-131 372.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,3F3VZ@33958|Lactobacillaceae 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro MHFCBNDO_02643 543734.LCABL_27160 5.04e-232 639.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F3RM@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N MHFCBNDO_02644 543734.LCABL_27170 0.0 914.0 COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,4HDTN@91061|Bacilli,3F3QW@33958|Lactobacillaceae 91061|Bacilli S Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_4,YkuD MHFCBNDO_02645 543734.LCABL_27210 1.34e-154 434.0 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,3F3JY@33958|Lactobacillaceae 91061|Bacilli S (CBS) domain - - - - - - - - - - - - CBS MHFCBNDO_02646 543734.LCABL_27220 1.19e-168 471.0 COG1376@1|root,COG1376@2|Bacteria,1V4KP@1239|Firmicutes,4HIBF@91061|Bacilli,3F6PH@33958|Lactobacillaceae 91061|Bacilli M ErfK YbiS YcfS YnhG yciB - - - - - - - - - - - YkuD MHFCBNDO_02647 543734.LCABL_27230 0.0 981.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4HAD5@91061|Bacilli,3FB6A@33958|Lactobacillaceae 91061|Bacilli E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iSB619.SA_RS02450 Fer4_20,Pyr_redox_2 MHFCBNDO_02648 543734.LCABL_27240 0.0 2949.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,3F4TU@33958|Lactobacillaceae 91061|Bacilli E GXGXG motif gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase MHFCBNDO_02649 543734.LCABL_27250 1.63e-111 321.0 COG4708@1|root,COG4708@2|Bacteria,1V463@1239|Firmicutes,4HH0P@91061|Bacilli,3FCEF@33958|Lactobacillaceae 91061|Bacilli S QueT transporter queT - - - - - - - - - - - QueT MHFCBNDO_02650 543734.LCABL_27260 5.68e-83 245.0 COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,4HGXF@91061|Bacilli,3F6Y9@33958|Lactobacillaceae 91061|Bacilli L Toxic component of a toxin-antitoxin (TA) module ndoA - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin MHFCBNDO_02651 1423816.BACQ01000044_gene1675 4.66e-44 144.0 29PVB@1|root,30ATJ@2|Bacteria,1U736@1239|Firmicutes,4IGXQ@91061|Bacilli,3F8WZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02652 543734.LCABL_27280 1.62e-277 758.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,3F3X2@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N MHFCBNDO_02653 543734.LCABL_27290 2.63e-82 243.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,3F6HC@33958|Lactobacillaceae 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS MHFCBNDO_02654 543734.LCABL_27300 0.0 963.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,3F46Q@33958|Lactobacillaceae 91061|Bacilli F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C MHFCBNDO_02656 543734.LCABL_27310 0.0 903.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,3F4SK@33958|Lactobacillaceae 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M MHFCBNDO_02657 543734.LCABL_27320 4.87e-187 519.0 29SV9@1|root,30E1E@2|Bacteria,1V46E@1239|Firmicutes,4HI7R@91061|Bacilli,3F6E2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02658 568703.LGG_00849 3.44e-08 53.1 29QSF@1|root,30BSA@2|Bacteria,1U8JX@1239|Firmicutes,4IIHW@91061|Bacilli,3FB2A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02659 543734.LCABL_27330 4.18e-157 440.0 COG0457@1|root,COG0457@2|Bacteria,1VQ45@1239|Firmicutes,4HRFF@91061|Bacilli,3F62R@33958|Lactobacillaceae 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - SUKH_6 MHFCBNDO_02660 543734.LCABL_27340 3.04e-162 454.0 2DNW7@1|root,32ZGM@2|Bacteria,1V8QF@1239|Firmicutes,4HIIB@91061|Bacilli,3F601@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02661 1423816.BACQ01000043_gene1667 2.29e-87 258.0 29Q2X@1|root,30B1I@2|Bacteria,1U7DP@1239|Firmicutes,4IH9K@91061|Bacilli,3F9FK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02662 543734.LCABL_27360 2.28e-57 177.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HKF0@91061|Bacilli,3F7D7@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L31 rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 MHFCBNDO_02663 543734.LCABL_27370 1.35e-299 817.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,3F3P8@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase MHFCBNDO_02664 543734.LCABL_27380 0.0 1066.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,3F42X@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase MHFCBNDO_02665 543734.LCABL_27390 3.42e-202 560.0 COG3548@1|root,COG3548@2|Bacteria,1VNI3@1239|Firmicutes,4HSHZ@91061|Bacilli,3F5J9@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) ybbB - - - - - - - - - - - DUF1211 MHFCBNDO_02666 543734.LCABL_27400 1.15e-111 326.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,3F55D@33958|Lactobacillaceae 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE - - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH MHFCBNDO_02667 543734.LCABL_27410 3.48e-103 298.0 COG4506@1|root,COG4506@2|Bacteria,1V8IZ@1239|Firmicutes,4HIW0@91061|Bacilli,3F6AI@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1934) ywiB - - - - - - - - - - - DUF1934 MHFCBNDO_02668 543734.LCABL_27420 1.63e-199 553.0 COG0095@1|root,COG0095@2|Bacteria,1TQKA@1239|Firmicutes,4HCPS@91061|Bacilli,3F575@33958|Lactobacillaceae 91061|Bacilli H biotin lipoate A B protein ligase lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 - - - - ko00000,ko01000 - - - BPL_LplA_LipB MHFCBNDO_02669 543734.LCABL_27430 0.0 923.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,3F442@33958|Lactobacillaceae 91061|Bacilli S HD domain protein ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD MHFCBNDO_02670 1423816.BACQ01000037_gene1572 1.41e-103 299.0 COG0494@1|root,COG0494@2|Bacteria,1VD6I@1239|Firmicutes,4HKRW@91061|Bacilli,3F75N@33958|Lactobacillaceae 91061|Bacilli L NUDIX domain mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX MHFCBNDO_02671 543734.LCABL_27450 4.32e-237 654.0 COG1434@1|root,COG1434@2|Bacteria,1UR34@1239|Firmicutes,4HDF2@91061|Bacilli,3F4J5@33958|Lactobacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 MHFCBNDO_02672 543734.LCABL_27460 1.31e-77 231.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,3F6YZ@33958|Lactobacillaceae 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL MHFCBNDO_02673 543734.LCABL_27470 5.62e-103 299.0 COG0786@1|root,COG0786@2|Bacteria,1TS2B@1239|Firmicutes,4HCID@91061|Bacilli,3F5R6@33958|Lactobacillaceae 91061|Bacilli E glutamate:sodium symporter activity - - - - - - - - - - - - - MHFCBNDO_02674 543734.LCABL_27480 1.54e-73 220.0 COG4043@1|root,COG4043@2|Bacteria,1VEJD@1239|Firmicutes,4HNU5@91061|Bacilli 91061|Bacilli S ASCH nudA - - - - - - - - - - - ASCH MHFCBNDO_02675 1423816.BACQ01000037_gene1564 2.2e-225 622.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3U2@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N MHFCBNDO_02676 543734.LCABL_27510 1.34e-298 818.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,3F4I3@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase MHFCBNDO_02677 543734.LCABL_27520 1.15e-282 773.0 COG4767@1|root,COG4767@2|Bacteria,1V04Y@1239|Firmicutes,4HDS5@91061|Bacilli,3F3SH@33958|Lactobacillaceae 91061|Bacilli V RDD family ysaA - - - - - - - - - - - RDD,VanZ MHFCBNDO_02678 543734.LCABL_27530 1.18e-192 535.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,3F3NH@33958|Lactobacillaceae 91061|Bacilli F pur operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N MHFCBNDO_02679 543734.LCABL_27540 1.29e-154 434.0 COG4619@1|root,COG4619@2|Bacteria,1V3DQ@1239|Firmicutes,4HHGU@91061|Bacilli,3F4UY@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ybbL - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran MHFCBNDO_02680 543734.LCABL_27550 5.89e-158 445.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,3F4P1@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0014) ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 MHFCBNDO_02681 543734.LCABL_27560 1.99e-205 568.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,3F4KJ@33958|Lactobacillaceae 91061|Bacilli P cation diffusion facilitator family transporter czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux MHFCBNDO_02682 543734.LCABL_27570 1.28e-229 632.0 COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,3F43W@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.29 - iYO844.BSU00460 GHMP_kinases_C,GHMP_kinases_N MHFCBNDO_02683 543734.LCABL_27580 2.39e-50 159.0 COG4466@1|root,COG4466@2|Bacteria,1VEQM@1239|Firmicutes,4HKF8@91061|Bacilli,3F7D3@33958|Lactobacillaceae 91061|Bacilli S Biofilm formation stimulator VEG veg - - - - - - - - - - - VEG MHFCBNDO_02684 543734.LCABL_27590 5.84e-202 560.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,3F3VC@33958|Lactobacillaceae 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD MHFCBNDO_02685 543734.LCABL_27600 6.78e-130 369.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,3F64F@33958|Lactobacillaceae 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 MHFCBNDO_02686 543734.LCABL_27610 9.1e-190 526.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,3F3N2@33958|Lactobacillaceae 91061|Bacilli L hydrolase, TatD family tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase MHFCBNDO_02687 543734.LCABL_27620 4.26e-103 299.0 COG1762@1|root,COG1762@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system manR - 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB MHFCBNDO_02688 543734.LCABL_27630 1.35e-239 658.0 COG3684@1|root,COG3684@2|Bacteria,1TQRR@1239|Firmicutes,4HBS9@91061|Bacilli,3F3UA@33958|Lactobacillaceae 91061|Bacilli G Belongs to the aldolase LacD family lacD - 4.1.2.40 ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 - R01069 RC00438,RC00439 ko00000,ko00001,ko01000 - - - DeoC MHFCBNDO_02689 543734.LCABL_27640 1.22e-220 607.0 COG2017@1|root,COG2017@2|Bacteria,1V3WP@1239|Firmicutes,4HHIH@91061|Bacilli,3F5RU@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase yqhA - - - - - - - - - - - Aldose_epim MHFCBNDO_02690 543734.LCABL_27650 1.32e-156 440.0 COG3279@1|root,COG3279@2|Bacteria,1TRDQ@1239|Firmicutes,4HP0H@91061|Bacilli,3FC2V@33958|Lactobacillaceae 91061|Bacilli T LytTr DNA-binding domain - - - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg MHFCBNDO_02691 543734.LCABL_27660 2.89e-199 554.0 COG3290@1|root,COG3290@2|Bacteria,1UZ9P@1239|Firmicutes,4HQIT@91061|Bacilli 91061|Bacilli T GHKL domain - - - - - - - - - - - - HATPase_c_5,SPOB_a MHFCBNDO_02692 543734.LCABL_27670 0.0 1151.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli,3F604@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_tran MHFCBNDO_02693 543734.LCABL_27680 0.0 1164.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli,3F53S@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_tran MHFCBNDO_02694 543734.LCABL_27690 0.0 1324.0 COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,3F3XR@33958|Lactobacillaceae 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind MHFCBNDO_02695 543734.LCABL_27700 1.67e-222 612.0 COG2267@1|root,COG2267@2|Bacteria,1TRMT@1239|Firmicutes,4HE23@91061|Bacilli,3F40N@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepI - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 MHFCBNDO_02696 543734.LCABL_27710 1.7e-195 541.0 COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,4HA0X@91061|Bacilli,3F40Y@33958|Lactobacillaceae 91061|Bacilli F Protein of unknown function DUF72 yunF - - - - - - - - - - - DUF72 MHFCBNDO_02697 543734.LCABL_27720 1.09e-118 338.0 COG1051@1|root,COG1051@2|Bacteria,1VAC7@1239|Firmicutes,4HKN6@91061|Bacilli,3F7HC@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX MHFCBNDO_02698 543734.LCABL_27730 3.11e-218 602.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli,3F4M2@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily - - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N MHFCBNDO_02699 543734.LCABL_27740 9.14e-139 392.0 COG3548@1|root,COG3548@2|Bacteria,1VAQZ@1239|Firmicutes,4HJFH@91061|Bacilli,3F6Q5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) yiiE - - - - - - - - - - - DUF1211 MHFCBNDO_02700 543734.LCABL_27750 5.67e-165 461.0 COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HGHS@91061|Bacilli,3FC3Y@33958|Lactobacillaceae 91061|Bacilli K Sir2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 MHFCBNDO_02701 543734.LCABL_27760 2.62e-23 89.0 29QQH@1|root,30BQA@2|Bacteria,1U8GG@1239|Firmicutes,4IIE9@91061|Bacilli,3FAYF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02702 543734.LCABL_27770 5.59e-220 607.0 296WI@1|root,2ZU5A@2|Bacteria,1VT7R@1239|Firmicutes,4HVBN@91061|Bacilli,3F4R1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02704 543734.LCABL_27780 1.31e-124 354.0 COG1881@1|root,COG1881@2|Bacteria,1VJEE@1239|Firmicutes,4HXTJ@91061|Bacilli,3F75J@33958|Lactobacillaceae 91061|Bacilli S Phosphatidylethanolamine-binding protein yxkA - - ko:K06910 - - - - ko00000 - - - PBP MHFCBNDO_02705 543734.LCABL_27790 6.68e-50 159.0 29BUI@1|root,2ZYSU@2|Bacteria,1U6QJ@1239|Firmicutes,4IGHU@91061|Bacilli,3F8B7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02706 1423732.BALS01000010_gene1903 3.25e-203 566.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli,3FBNF@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1002) ypuA - - - - - - - - - - - DUF1002 MHFCBNDO_02707 543734.LCABL_27810 2.57e-223 615.0 COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,3F3SR@33958|Lactobacillaceae 91061|Bacilli FP exopolyphosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA MHFCBNDO_02708 543734.LCABL_27820 0.0 1412.0 COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,4HA88@91061|Bacilli,3F3PE@33958|Lactobacillaceae 91061|Bacilli P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N MHFCBNDO_02709 543734.LCABL_27830 0.0 984.0 COG0248@1|root,COG0248@2|Bacteria,1VT8Q@1239|Firmicutes,4HB84@91061|Bacilli,3F49N@33958|Lactobacillaceae 91061|Bacilli FP exopolyphosphatase ppx3 - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA MHFCBNDO_02710 543734.LCABL_27840 1.74e-224 618.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,3F4U1@33958|Lactobacillaceae 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red MHFCBNDO_02711 543734.LCABL_27850 5.94e-198 548.0 COG0500@1|root,COG2226@2|Bacteria,1UIXT@1239|Firmicutes,4ISW5@91061|Bacilli 91061|Bacilli Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 MHFCBNDO_02712 543734.LCABL_27860 6.5e-119 339.0 COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,3F70T@33958|Lactobacillaceae 91061|Bacilli M Acetyltransferase (GNAT) domain ywnH GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_3,Acetyltransf_4 MHFCBNDO_02713 543734.LCABL_27870 5.58e-306 836.0 COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli,3FC3X@33958|Lactobacillaceae 91061|Bacilli V MatE dinF - - - - - - - - - - - MatE MHFCBNDO_02714 543734.LCABL_27880 7.19e-157 445.0 COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4HJVB@91061|Bacilli,3F5HD@33958|Lactobacillaceae 91061|Bacilli S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase MHFCBNDO_02715 543734.LCABL_27890 1.4e-133 379.0 COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,4HH6X@91061|Bacilli,3FCF0@33958|Lactobacillaceae 91061|Bacilli S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA MHFCBNDO_02716 543734.LCABL_27900 1.48e-246 676.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,3F3V6@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b MHFCBNDO_02717 543734.LCABL_27920 2.13e-254 713.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX MHFCBNDO_02718 543734.LCABL_27950 0.0 873.0 COG1249@1|root,COG1249@2|Bacteria,1TS0Z@1239|Firmicutes,4HBYB@91061|Bacilli,3F3K2@33958|Lactobacillaceae 91061|Bacilli C Glutathione reductase gshR - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim MHFCBNDO_02719 543734.LCABL_27960 6.07e-225 620.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,3F55H@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran MHFCBNDO_02720 543734.LCABL_27970 0.0 958.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HBDR@91061|Bacilli,3F44S@33958|Lactobacillaceae 91061|Bacilli EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) choS - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC MHFCBNDO_02722 543734.LCABL_27980 0.0 1485.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,3F486@33958|Lactobacillaceae 91061|Bacilli L DNA helicase - - - - - - - - - - - - AAA_19,UvrD_C_2 MHFCBNDO_02723 543734.LCABL_27990 1.98e-193 537.0 COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,4HC4T@91061|Bacilli,3F4VC@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator rlrG - - ko:K21900 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate MHFCBNDO_02724 543734.LCABL_28000 1.32e-221 612.0 COG1275@1|root,COG1275@2|Bacteria,1UYTE@1239|Firmicutes,4HGBI@91061|Bacilli,3FBRC@33958|Lactobacillaceae 91061|Bacilli P Voltage-dependent anion channel ydiA - - ko:K11041 ko05150,map05150 - - - ko00000,ko00001,ko02042 2.A.16 - - SLAC1 MHFCBNDO_02725 543734.LCABL_28010 1.15e-147 416.0 COG1266@1|root,COG1266@2|Bacteria,1VFRX@1239|Firmicutes,4HRQQ@91061|Bacilli,3F4Q0@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi MHFCBNDO_02727 543734.LCABL_28030 7.3e-149 419.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,3F3PN@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yagB - - ko:K06950 - - - - ko00000 - - - HD MHFCBNDO_02728 543734.LCABL_28040 6.41e-92 269.0 29Q5J@1|root,30B4H@2|Bacteria,1U7IQ@1239|Firmicutes,4IHFG@91061|Bacilli,3F9S0@33958|Lactobacillaceae 91061|Bacilli K MarR family - - - - - - - - - - - - MarR_2 MHFCBNDO_02729 543734.LCABL_28050 0.0 1658.0 COG0178@1|root,COG0178@2|Bacteria,1TP0A@1239|Firmicutes,4HTKA@91061|Bacilli,3FC8R@33958|Lactobacillaceae 91061|Bacilli L excinuclease ABC uvrA3 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran MHFCBNDO_02730 543734.LCABL_28060 6.25e-246 674.0 COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,4HAZ2@91061|Bacilli,3F414@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase family protein yghZ - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red MHFCBNDO_02731 543734.LCABL_28070 5.86e-187 520.0 COG0561@1|root,COG0561@2|Bacteria,1V8IN@1239|Firmicutes,4HJUX@91061|Bacilli,3F5CU@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - - - - - - - - - - - Hydrolase_3 MHFCBNDO_02732 543734.LCABL_28080 4.04e-79 234.0 29PSZ@1|root,30AR5@2|Bacteria,1U708@1239|Firmicutes,4IGUJ@91061|Bacilli,3F8T2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02733 1074451.CRL705_1431 1.99e-16 73.9 2DKPT@1|root,30A91@2|Bacteria,1U6CF@1239|Firmicutes,4IG44@91061|Bacilli,3F7KP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF2187 MHFCBNDO_02734 543734.LCABL_28100 3.43e-138 392.0 COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,4HM4F@91061|Bacilli,3F5F5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 MHFCBNDO_02735 543734.LCABL_28110 6.36e-161 451.0 COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HJ9X@91061|Bacilli,3FC5R@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpmB - - ko:K15640 - - - - ko00000 - - - His_Phos_1 MHFCBNDO_02736 543734.LCABL_28120 7.22e-197 545.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,3F47B@33958|Lactobacillaceae 91061|Bacilli S hydrolase yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 MHFCBNDO_02737 543734.LCABL_28130 1.09e-114 328.0 COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,4HHJ9@91061|Bacilli,3F3RG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - Cauli_VI,RNase_H MHFCBNDO_02738 543734.LCABL_28140 4.39e-213 588.0 COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,4HCXX@91061|Bacilli,3F4HW@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate MHFCBNDO_02739 543734.LCABL_28150 4.96e-290 791.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4H9M3@91061|Bacilli,3F4AH@33958|Lactobacillaceae 91061|Bacilli EK Aminotransferase, class I - - - - - - - - - - - - Aminotran_1_2 MHFCBNDO_02740 543734.LCABL_28180 1.97e-235 653.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA MHFCBNDO_02741 543734.LCABL_28190 1.27e-153 432.0 COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,4HB4E@91061|Bacilli,3FB62@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF554) ydfK - - ko:K07150 - - - - ko00000 - - - DUF554 MHFCBNDO_02742 543734.LCABL_28200 5.24e-116 331.0 29P3K@1|root,30AWC@2|Bacteria,1U76S@1239|Firmicutes,4IH1K@91061|Bacilli,3F91T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02743 543734.LCABL_28210 0.0 1263.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F5D3@33958|Lactobacillaceae 91061|Bacilli GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 fruC - 2.7.1.202 ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB MHFCBNDO_02744 543734.LCABL_28220 1.09e-222 613.0 COG1105@1|root,COG1105@2|Bacteria,1TTI9@1239|Firmicutes,4HCRN@91061|Bacilli,3F537@33958|Lactobacillaceae 91061|Bacilli H pfkB family carbohydrate kinase fruK-1 - 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB MHFCBNDO_02745 543734.LCABL_28230 2.36e-167 469.0 COG1737@1|root,COG1737@2|Bacteria,1TP26@1239|Firmicutes,4HDKG@91061|Bacilli,3F681@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family rpl - - - - - - - - - - - HTH_6,SIS MHFCBNDO_02746 543734.LCABL_28240 0.0 1007.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,3F3WI@33958|Lactobacillaceae 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N MHFCBNDO_02747 543734.LCABL_28260 2.22e-174 486.0 COG2188@1|root,COG2188@2|Bacteria,1VCJ9@1239|Firmicutes,4HM7V@91061|Bacilli,3F6DC@33958|Lactobacillaceae 91061|Bacilli K UTRA domain - - - - - - - - - - - - GntR,UTRA MHFCBNDO_02748 543734.LCABL_28270 0.0 863.0 COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,4HDR0@91061|Bacilli,3F4YW@33958|Lactobacillaceae 91061|Bacilli G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos MHFCBNDO_02749 543734.LCABL_28280 1.16e-214 593.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4HIM5@91061|Bacilli,3FBI1@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man,PTSIIB_sorb MHFCBNDO_02750 543734.LCABL_28290 2.3e-167 470.0 COG3715@1|root,COG3715@2|Bacteria,1UYP8@1239|Firmicutes,4HFQS@91061|Bacilli,3FC9E@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor MHFCBNDO_02751 543734.LCABL_28300 4.71e-191 531.0 COG3716@1|root,COG3716@2|Bacteria,1UMKU@1239|Firmicutes,4HCQB@91061|Bacilli,3FBHN@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA MHFCBNDO_02752 543734.LCABL_28310 8.88e-63 192.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,3F7SW@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit celC - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA MHFCBNDO_02753 543734.LCABL_28320 2.1e-65 199.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F77Q@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit ptcB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB MHFCBNDO_02754 543734.LCABL_28330 0.0 988.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,3FC7B@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bgl - 3.2.1.21,3.2.1.85,3.2.1.86 ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03256,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 MHFCBNDO_02755 543734.LCABL_28340 5.67e-200 555.0 COG1940@1|root,COG1940@2|Bacteria,1UZ80@1239|Firmicutes,4HD5J@91061|Bacilli,3FBD4@33958|Lactobacillaceae 91061|Bacilli GK ROK family ypbG - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK MHFCBNDO_02756 543734.LCABL_28350 5.65e-314 855.0 COG3538@1|root,COG3538@2|Bacteria,1TRJI@1239|Firmicutes,4HBQW@91061|Bacilli,3F535@33958|Lactobacillaceae 91061|Bacilli S Metal-independent alpha-mannosidase (GH125) - - - ko:K09704 - - - - ko00000 - - - Glyco_hydro_125 MHFCBNDO_02757 543734.LCABL_28360 0.0 1742.0 COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HBC7@91061|Bacilli,3F4XS@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 38 N-terminal domain mngB - 3.2.1.170 ko:K15524 - - - - ko00000,ko01000 - GH38 - Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C MHFCBNDO_02758 543734.LCABL_28370 3.63e-306 836.0 COG1455@1|root,COG1455@2|Bacteria,1TSXJ@1239|Firmicutes,4HU65@91061|Bacilli,3F5IS@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane - - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC MHFCBNDO_02759 543734.LCABL_28380 1.1e-172 481.0 COG2188@1|root,COG2188@2|Bacteria,1TTCD@1239|Firmicutes,4HEXQ@91061|Bacilli,3F4DA@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein - - - ko:K03492 - - - - ko00000,ko03000 - - - GntR,UTRA MHFCBNDO_02760 543734.LCABL_28390 1.51e-175 489.0 COG0235@1|root,COG0235@2|Bacteria,1V57Z@1239|Firmicutes,4HGYY@91061|Bacilli,3FCAV@33958|Lactobacillaceae 91061|Bacilli G Class II Aldolase and Adducin N-terminal domain - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II MHFCBNDO_02762 543734.LCABL_28410 0.0 942.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HAIT@91061|Bacilli,3FCCE@33958|Lactobacillaceae 91061|Bacilli G PTS system sugar-specific permease component pts36C - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT MHFCBNDO_02763 543734.LCABL_28420 1.52e-68 207.0 COG3414@1|root,COG3414@2|Bacteria,1VAU7@1239|Firmicutes,4IR9X@91061|Bacilli,3F7JF@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_IIB MHFCBNDO_02764 543734.LCABL_28430 3.66e-108 311.0 COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes,4HPPC@91061|Bacilli,3F7U5@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 pts36A - 2.7.1.200 ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_EIIA_2 MHFCBNDO_02765 543734.LCABL_28440 5.43e-185 514.0 COG1349@1|root,COG1349@2|Bacteria,1V1VH@1239|Firmicutes,4HG12@91061|Bacilli,3FC5U@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain rdrB - - ko:K02444,ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR MHFCBNDO_02766 543734.LCABL_28450 9.56e-208 573.0 COG1092@1|root,COG1092@2|Bacteria,1UM09@1239|Firmicutes,4ITNI@91061|Bacilli,3F5VI@33958|Lactobacillaceae 91061|Bacilli J Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 MHFCBNDO_02767 543734.LCABL_28460 0.0 1179.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein - - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,Malt_amylase_C MHFCBNDO_02769 543734.LCABL_28650 2.41e-149 420.0 COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,4HFXG@91061|Bacilli,3F4B1@33958|Lactobacillaceae 91061|Bacilli L DNA alkylation repair enzyme alkD - - - - - - - - - - - DNA_alkylation MHFCBNDO_02770 543734.LCABL_28660 4.14e-162 454.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,3F43N@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A MHFCBNDO_02771 543734.LCABL_28670 0.0 1231.0 COG1807@1|root,COG1807@2|Bacteria,1UYWB@1239|Firmicutes,4HTZD@91061|Bacilli,3F5AG@33958|Lactobacillaceae 91061|Bacilli M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - MHFCBNDO_02772 543734.LCABL_28680 2.36e-219 605.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,3F3X7@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 2 ykoT - - - - - - - - - - - Glycos_transf_2 MHFCBNDO_02773 543734.LCABL_28690 1.73e-148 419.0 COG0671@1|root,COG0671@2|Bacteria,1VY85@1239|Firmicutes,4HXM4@91061|Bacilli,3F4DD@33958|Lactobacillaceae 91061|Bacilli I phosphatase - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2,PAP2_3 MHFCBNDO_02774 543734.LCABL_28700 1.62e-149 421.0 COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,4HG3F@91061|Bacilli,3F4KG@33958|Lactobacillaceae 91061|Bacilli S SNARE-like domain protein - - - ko:K03975 - - - - ko00000 - - - SNARE_assoc MHFCBNDO_02775 543734.LCABL_28710 1.71e-156 457.0 COG0642@1|root,COG2205@2|Bacteria,1VU2I@1239|Firmicutes,4HHZT@91061|Bacilli,3F475@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase kinE - - - - - - - - - - - HAMP,HATPase_c,HisKA MHFCBNDO_02776 543734.LCABL_28730 0.0 936.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9TM@91061|Bacilli,3F4W5@33958|Lactobacillaceae 91061|Bacilli G Family 4 glycosyl hydrolase C-terminal domain - - 3.2.1.122 ko:K01232 ko00500,map00500 - R00837,R00838,R06113 RC00049 ko00000,ko00001,ko01000 - GH4 - Glyco_hydro_4,Glyco_hydro_4C MHFCBNDO_02777 543734.LCABL_28740 0.0 1017.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,3F44V@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system, EIIB - - 2.7.1.199,2.7.1.208 ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266 R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.3 - - PTS_EIIB,PTS_EIIC MHFCBNDO_02778 543734.LCABL_28750 0.0 1939.0 COG5492@1|root,COG5492@2|Bacteria,1TQ2K@1239|Firmicutes,4HBG8@91061|Bacilli,3F9RZ@33958|Lactobacillaceae 91061|Bacilli N Polysaccharide lyase family 8, N terminal alpha-helical domain hylB GO:0005575,GO:0005576 4.2.2.1 ko:K01727 - - - - ko00000,ko01000 - PL8 - Big_2,F5_F8_type_C,FIVAR,Gram_pos_anchor,Lyase_8,Lyase_8_C,Lyase_8_N,SLH,YSIRK_signal MHFCBNDO_02780 543734.LCABL_28760 0.0 1216.0 2DVNR@1|root,33WIQ@2|Bacteria,1VVQM@1239|Firmicutes,4HWSH@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02782 543734.LCABL_28810 1.35e-143 405.0 2F49V@1|root,33X0H@2|Bacteria,1VWJ1@1239|Firmicutes,4HWUD@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02783 543734.LCABL_28820 6.42e-112 322.0 2DJFW@1|root,305ZW@2|Bacteria,1TYZ0@1239|Firmicutes,4HW93@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02784 543734.LCABL_28830 1e-174 498.0 COG3711@1|root,COG3711@2|Bacteria,1V9WD@1239|Firmicutes,4HJD0@91061|Bacilli 91061|Bacilli K M protein trans-acting positive regulator - - - - - - - - - - - - Mga MHFCBNDO_02785 543734.LCABL_28870 2.19e-152 430.0 COG1737@1|root,COG1737@2|Bacteria,1TR75@1239|Firmicutes,4HJU7@91061|Bacilli,3F6Y6@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS MHFCBNDO_02786 543734.LCABL_28880 2.57e-109 315.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,3FC0X@33958|Lactobacillaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ptbA - 2.7.1.208 ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1 MHFCBNDO_02787 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_02790 768486.EHR_05290 1.61e-85 256.0 COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,4HHPU@91061|Bacilli,4B1KC@81852|Enterococcaceae 91061|Bacilli S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 MHFCBNDO_02791 1545702.LACWKB8_1629 4.52e-97 289.0 COG0149@1|root,COG0149@2|Bacteria,1UZAR@1239|Firmicutes,4HBA2@91061|Bacilli,3F9SE@33958|Lactobacillaceae 91061|Bacilli G Triose-phosphate isomerase - - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM MHFCBNDO_02792 1545702.LACWKB8_1630 1.24e-122 358.0 COG0191@1|root,COG0191@2|Bacteria,1TRQY@1239|Firmicutes,4HC8E@91061|Bacilli,3FCBB@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II gatY - 4.1.2.13,4.1.2.40 ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01069,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase MHFCBNDO_02793 873448.STRPO_1585 6.66e-41 137.0 COG3414@1|root,COG3414@2|Bacteria,1VCNU@1239|Firmicutes,4HM3X@91061|Bacilli 91061|Bacilli G Phosphotransferase system, galactitol-specific IIB component - - 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_IIB MHFCBNDO_02794 1114972.AUAW01000022_gene1261 1.05e-203 577.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HA1Q@91061|Bacilli,3F427@33958|Lactobacillaceae 91061|Bacilli G PTS system sugar-specific permease component - - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT MHFCBNDO_02795 46256.BBIK01000001_gene130 3.77e-33 121.0 COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes,4HMCG@91061|Bacilli,4AY39@81850|Leuconostocaceae 91061|Bacilli G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) - - 2.7.1.200 ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_EIIA_2 MHFCBNDO_02797 1545702.LACWKB8_1633 9.87e-99 313.0 COG3711@1|root,COG3711@2|Bacteria,1TSGM@1239|Firmicutes,4HB3W@91061|Bacilli,3F482@33958|Lactobacillaceae 91061|Bacilli K PRD domain - - - ko:K02538 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB MHFCBNDO_02798 543734.LCABL_28900 6.59e-256 703.0 COG0457@1|root,COG1434@1|root,COG0457@2|Bacteria,COG1434@2|Bacteria,1V0QQ@1239|Firmicutes,4I373@91061|Bacilli,3FAS6@33958|Lactobacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 MHFCBNDO_02799 35841.BT1A1_2898 1.96e-155 445.0 COG1995@1|root,COG1995@2|Bacteria,1TQGT@1239|Firmicutes,4HA7N@91061|Bacilli,1ZCWV@1386|Bacillus 91061|Bacilli H Belongs to the PdxA family pdxA - 1.1.1.408,1.1.1.409 ko:K22024 - - - - ko00000,ko01000 - - - PdxA MHFCBNDO_02800 35841.BT1A1_2899 1.49e-108 332.0 COG3395@1|root,COG3395@2|Bacteria,1TPNP@1239|Firmicutes,4HAGQ@91061|Bacilli,1ZD9B@1386|Bacillus 91061|Bacilli S Putative nucleotide-binding of sugar-metabolising enzyme - - 2.7.1.219,2.7.1.220 ko:K22129 - - - - ko00000,ko01000 - - - DUF1357_C,DUF1537 MHFCBNDO_02801 35841.BT1A1_2900 7.77e-132 385.0 28H7K@1|root,2Z7JT@2|Bacteria,1UPH1@1239|Firmicutes,4HE88@91061|Bacilli,1ZDHF@1386|Bacillus 91061|Bacilli P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system kdgT - - ko:K02526 - - - - ko00000,ko02000 2.A.10.1 - - KdgT MHFCBNDO_02802 457421.CBFG_02570 1.52e-71 248.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,PrpR_N,Sigma54_activ_2,Sigma54_activat MHFCBNDO_02803 1423775.BAMN01000013_gene765 1.75e-84 255.0 COG0794@1|root,COG0794@2|Bacteria,1TQ04@1239|Firmicutes,4HGZ0@91061|Bacilli,3F7HT@33958|Lactobacillaceae 91061|Bacilli M SIS domain kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS MHFCBNDO_02804 1423775.BAMN01000013_gene764 8.2e-63 196.0 COG1762@1|root,COG1762@2|Bacteria,1V42N@1239|Firmicutes,4HP6Y@91061|Bacilli 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_EIIA_2 MHFCBNDO_02805 1423775.BAMN01000013_gene763 8.29e-44 144.0 COG3414@1|root,COG3414@2|Bacteria,1VFJK@1239|Firmicutes,4HQ69@91061|Bacilli,3F8MG@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB MHFCBNDO_02806 1423775.BAMN01000013_gene762 1.77e-256 708.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HBAD@91061|Bacilli,3F4Y4@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component - - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT MHFCBNDO_02807 1423775.BAMN01000013_gene761 1.46e-122 359.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4IQWR@91061|Bacilli,3FBJP@33958|Lactobacillaceae 91061|Bacilli E Dihydrodipicolinate synthetase family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS MHFCBNDO_02808 1423775.BAMN01000013_gene760 1.08e-104 307.0 COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,3F6AY@33958|Lactobacillaceae 91061|Bacilli G KDPG and KHG aldolase eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase MHFCBNDO_02809 1423775.BAMN01000013_gene759 1.33e-255 728.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4H9N4@91061|Bacilli,3F5NN@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB MHFCBNDO_02810 543734.LCABL_28910 4.63e-176 491.0 2DBAP@1|root,2Z844@2|Bacteria,1TQX7@1239|Firmicutes,4HABQ@91061|Bacilli,3F5QS@33958|Lactobacillaceae 91061|Bacilli S KDGP aldolase - - 4.1.2.14 ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 M00061,M00631 R05605 RC00307,RC00435 ko00000,ko00001,ko00002,ko01000 - - - KDGP_aldolase MHFCBNDO_02811 543734.LCABL_28920 1.51e-260 714.0 COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,4HC3U@91061|Bacilli,3F4MN@33958|Lactobacillaceae 91061|Bacilli H L-seryl-tRNA selenium transferase selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - SelA MHFCBNDO_02812 543734.LCABL_28930 2.47e-274 749.0 COG3964@1|root,COG3964@2|Bacteria,1TPXM@1239|Firmicutes,4HBNV@91061|Bacilli,3F4S7@33958|Lactobacillaceae 91061|Bacilli S Amidohydrolase family dho - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 MHFCBNDO_02813 543734.LCABL_28940 3.79e-155 436.0 2CHGF@1|root,2Z7QV@2|Bacteria,1TRJJ@1239|Firmicutes,4HC0E@91061|Bacilli,3F5QZ@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4310) - - - - - - - - - - - - DUF4310 MHFCBNDO_02814 543734.LCABL_28950 4.79e-176 491.0 28HBR@1|root,2Z7NQ@2|Bacteria,1TQ2N@1239|Firmicutes,4HAZ6@91061|Bacilli,3F5N2@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4311) - - - - - - - - - - - - DUF4311 MHFCBNDO_02815 543734.LCABL_28960 1.1e-76 229.0 2AJY2@1|root,31AM7@2|Bacteria,1VQQN@1239|Firmicutes,4IRVB@91061|Bacilli,3F93K@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4312) - - - - - - - - - - - - DUF4312 MHFCBNDO_02816 543734.LCABL_28970 8.65e-81 239.0 292C3@1|root,2ZPWH@2|Bacteria,1V7VZ@1239|Firmicutes,4HIX7@91061|Bacilli,3F6XI@33958|Lactobacillaceae 91061|Bacilli S Glycine-rich SFCGS - - - - - - - - - - - - Gly_rich_SFCGS MHFCBNDO_02817 543734.LCABL_28980 7.4e-74 222.0 2CG0N@1|root,32S2X@2|Bacteria,1VI2Z@1239|Firmicutes,4HQX6@91061|Bacilli,3F8H0@33958|Lactobacillaceae 91061|Bacilli S PRD domain - - - - - - - - - - - - PRD MHFCBNDO_02818 543734.LCABL_28990 0.0 1187.0 COG3711@1|root,COG3711@2|Bacteria,1U0UU@1239|Firmicutes,4HJZ1@91061|Bacilli,3F5NV@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - HTH_11,PRD MHFCBNDO_02819 543734.LCABL_29000 8.74e-161 450.0 COG0176@1|root,COG0176@2|Bacteria,1V4IX@1239|Firmicutes,4HJYI@91061|Bacilli,3FCEA@33958|Lactobacillaceae 91061|Bacilli H Pfam:Transaldolase - - - - - - - - - - - - TAL_FSA MHFCBNDO_02820 543734.LCABL_29010 2.24e-84 249.0 COG3731@1|root,COG3731@2|Bacteria,1VG8V@1239|Firmicutes,4HPTF@91061|Bacilli,3F7KY@33958|Lactobacillaceae 91061|Bacilli G PTS system glucitol/sorbitol-specific IIA component - - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA MHFCBNDO_02821 543734.LCABL_29020 8.43e-261 715.0 COG3732@1|root,COG3732@2|Bacteria,1TQ8F@1239|Firmicutes,4HA7E@91061|Bacilli,3F5AP@33958|Lactobacillaceae 91061|Bacilli G Sorbitol phosphotransferase enzyme II N-terminus srlE - 2.7.1.198 ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - EIIBC-GUT_C,EIIBC-GUT_N MHFCBNDO_02822 543734.LCABL_29030 5.81e-131 372.0 COG3730@1|root,COG3730@2|Bacteria,1URER@1239|Firmicutes,4HEHX@91061|Bacilli,3F445@33958|Lactobacillaceae 91061|Bacilli G PTS system enzyme II sorbitol-specific factor srlA - - ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.4.1 - - EII-GUT MHFCBNDO_02823 543734.LCABL_29040 7.54e-115 329.0 COG4578@1|root,COG4578@2|Bacteria,1VHYU@1239|Firmicutes,4HP9S@91061|Bacilli,3F7F5@33958|Lactobacillaceae 91061|Bacilli K Glucitol operon activator protein (GutM) srlM1 - - - - - - - - - - - GutM MHFCBNDO_02824 543734.LCABL_29050 0.0 1207.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1UZ36@1239|Firmicutes,4HDUK@91061|Bacilli,3F5E0@33958|Lactobacillaceae 91061|Bacilli GKT Mga helix-turn-helix domain srlM - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2 MHFCBNDO_02825 543734.LCABL_29060 4.13e-185 515.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli,3F4CR@33958|Lactobacillaceae 91061|Bacilli IQ NAD dependent epimerase/dehydratase family srlD2 - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short MHFCBNDO_02826 655812.HMPREF0061_0255 2.29e-39 138.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,27EQG@186827|Aerococcaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ptbA - 2.7.1.208 ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1 MHFCBNDO_02827 469596.HMPREF9488_01999 2.48e-268 756.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,3VPPH@526524|Erysipelotrichia 526524|Erysipelotrichia C Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Oxidored_FMN,Pyr_redox_2 MHFCBNDO_02828 1274374.CBLK010000079_gene4024 1.57e-235 660.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,26QRQ@186822|Paenibacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 MHFCBNDO_02829 1274374.CBLK010000079_gene4025 3.16e-110 332.0 COG1609@1|root,COG1609@2|Bacteria,1TPH2@1239|Firmicutes,4HBMD@91061|Bacilli,26SN8@186822|Paenibacillaceae 91061|Bacilli K Transcriptional regulator rbsR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 MHFCBNDO_02830 1034347.CAHJ01000066_gene2915 1.23e-162 474.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZC3X@1386|Bacillus 91061|Bacilli G phosphotransferase system - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC MHFCBNDO_02831 543734.LCABL_29070 6.39e-177 492.0 COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,4H9W0@91061|Bacilli,3F43P@33958|Lactobacillaceae 91061|Bacilli G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source araD GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II MHFCBNDO_02832 543734.LCABL_29080 1.45e-193 537.0 COG0561@1|root,COG0561@2|Bacteria,1TR2E@1239|Firmicutes,4HCEA@91061|Bacilli,3F4G9@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 MHFCBNDO_02833 543734.LCABL_29090 6.24e-212 585.0 COG3623@1|root,COG3623@2|Bacteria,1TSMS@1239|Firmicutes,4HBBU@91061|Bacilli,3F5GZ@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase-like TIM barrel sga - 5.1.3.22 ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R03244 RC00540 ko00000,ko00001,ko00002,ko01000 - - - AP_endonuc_2 MHFCBNDO_02834 543734.LCABL_29100 8.64e-178 496.0 COG1349@1|root,COG1349@2|Bacteria,1UYQX@1239|Firmicutes,4HMB5@91061|Bacilli,3F6Z8@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR MHFCBNDO_02835 543734.LCABL_29110 5.26e-148 417.0 COG0269@1|root,COG0269@2|Bacteria,1TSHP@1239|Firmicutes,4HCA8@91061|Bacilli,3F3YT@33958|Lactobacillaceae 91061|Bacilli G Orotidine 5'-phosphate decarboxylase / HUMPS family ulaD - 4.1.1.85,4.1.2.43 ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 M00345,M00550,M00580 R05338,R07125 RC00421,RC00422,RC01721 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase MHFCBNDO_02836 543734.LCABL_29120 3.36e-61 188.0 COG3414@1|root,COG3414@2|Bacteria,1VHNP@1239|Firmicutes,4IR7Z@91061|Bacilli,3F78S@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit sgaB - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB MHFCBNDO_02837 543734.LCABL_29130 0.0 978.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HB7T@91061|Bacilli,3FC40@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component sgaT - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT MHFCBNDO_02838 543734.LCABL_29140 4.89e-105 303.0 COG1762@1|root,COG1762@2|Bacteria,1V892@1239|Firmicutes,4IQ69@91061|Bacilli,3F6HA@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_EIIA_2 MHFCBNDO_02839 543734.LCABL_29150 4.59e-275 750.0 COG2220@1|root,COG2220@2|Bacteria,1TSFV@1239|Firmicutes,4HBNW@91061|Bacilli,3F58F@33958|Lactobacillaceae 91061|Bacilli S Beta-lactamase superfamily domain ulaG - - ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 M00550 R07677 RC02793 ko00000,ko00001,ko00002,ko01000 - - - Lactamase_B_2,Lactamase_B_3 MHFCBNDO_02840 543734.LCABL_29160 4.14e-162 454.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,3F43N@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A MHFCBNDO_02841 543734.LCABL_29170 2.47e-251 689.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4HABC@91061|Bacilli,3F3WG@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase - - 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N MHFCBNDO_02842 543734.LCABL_29180 4.95e-117 340.0 COG1830@1|root,COG1830@2|Bacteria,1TR4S@1239|Firmicutes,4HWA1@91061|Bacilli,3F9XH@33958|Lactobacillaceae 91061|Bacilli G DeoC/LacD family aldolase - - - - - - - - - - - - DeoC MHFCBNDO_02843 543734.LCABL_29200 1.15e-154 434.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,3F4KX@33958|Lactobacillaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim MHFCBNDO_02844 543734.LCABL_29210 1.29e-201 559.0 COG3716@1|root,COG3716@2|Bacteria,1TRWR@1239|Firmicutes,4HUGC@91061|Bacilli,3FBHR@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA MHFCBNDO_02845 543734.LCABL_29220 1.95e-172 482.0 COG3715@1|root,COG3715@2|Bacteria,1TSZ2@1239|Firmicutes,4HTCA@91061|Bacilli,3F8K4@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor MHFCBNDO_02846 543734.LCABL_29230 2.79e-107 309.0 COG3444@1|root,COG3444@2|Bacteria,1V8X5@1239|Firmicutes,4HW54@91061|Bacilli,3FBAW@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb MHFCBNDO_02847 543734.LCABL_29240 5.03e-95 277.0 COG2893@1|root,COG2893@2|Bacteria,1UXMQ@1239|Firmicutes,4IHS7@91061|Bacilli,3FA7C@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man MHFCBNDO_02848 543734.LCABL_29250 5.08e-262 717.0 COG1063@1|root,COG1063@2|Bacteria,1TQSR@1239|Firmicutes,4HCCH@91061|Bacilli,3F4VQ@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate - - 1.1.1.405 ko:K05352 ko00040,ko01100,map00040,map01100 - R01525 RC00089 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N MHFCBNDO_02849 543734.LCABL_29260 1.67e-173 484.0 COG1349@1|root,COG1349@2|Bacteria,1V813@1239|Firmicutes,4HK5K@91061|Bacilli,3FBHY@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR MHFCBNDO_02850 543734.LCABL_29270 0.0 1634.0 COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,4HC2J@91061|Bacilli,3F3TZ@33958|Lactobacillaceae 91061|Bacilli G Phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N MHFCBNDO_02851 543734.LCABL_29280 5.08e-207 573.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,4HE30@91061|Bacilli,3F3ZI@33958|Lactobacillaceae 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK MHFCBNDO_02852 543734.LCABL_29290 6.65e-234 643.0 COG1446@1|root,COG1446@2|Bacteria,1TSWB@1239|Firmicutes,4HED0@91061|Bacilli,3F3SI@33958|Lactobacillaceae 91061|Bacilli E Asparaginase asnA2 - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase_2 MHFCBNDO_02853 543734.LCABL_29300 0.0 877.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HBQA@91061|Bacilli,3F5AY@33958|Lactobacillaceae 91061|Bacilli E Peptidase family M20/M25/M40 - - - - - - - - - - - - Peptidase_M20 MHFCBNDO_02854 543734.LCABL_29310 3.03e-169 473.0 COG2188@1|root,COG2188@2|Bacteria,1V338@1239|Firmicutes,4HGUM@91061|Bacilli,3F682@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA MHFCBNDO_02855 543734.LCABL_29320 0.0 1053.0 COG0436@1|root,COG0436@2|Bacteria,1TQP8@1239|Firmicutes,4HECY@91061|Bacilli 91061|Bacilli E Aminotransferase - - 4.1.1.12 ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 - R00397,R00863 RC00282,RC00399,RC00400 ko00000,ko00001,ko01000 - - - Aminotran_1_2 MHFCBNDO_02856 543734.LCABL_29330 1.37e-271 745.0 COG0477@1|root,COG2814@2|Bacteria,1TQZ7@1239|Firmicutes,4HERG@91061|Bacilli,3F54C@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein - - - - - - - - - - - - MFS_1 MHFCBNDO_02857 543734.LCABL_29340 1.7e-264 722.0 COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,4HTW2@91061|Bacilli,3F4ZS@33958|Lactobacillaceae 91061|Bacilli G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos MHFCBNDO_02858 543734.LCABL_29350 1.07e-93 275.0 2BMK9@1|root,30BB1@2|Bacteria,1U7UB@1239|Firmicutes,4HYFJ@91061|Bacilli,3FA6T@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4428) - - - - - - - - - - - - - MHFCBNDO_02859 543734.LCABL_29360 0.0 973.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,3F4R2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the FGGY kinase family - - 2.7.1.17,2.7.1.53 ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 M00014 R01639,R01901,R07127 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N MHFCBNDO_02860 543734.LCABL_29370 8.07e-260 711.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4HABC@91061|Bacilli,3F3WG@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase - - 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N MHFCBNDO_02861 543734.LCABL_29380 1.29e-197 548.0 COG3716@1|root,COG3716@2|Bacteria,1TT8N@1239|Firmicutes,4HUFH@91061|Bacilli,3F9BA@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA MHFCBNDO_02862 543734.LCABL_29390 3.52e-176 491.0 COG3715@1|root,COG3715@2|Bacteria,1TSZ2@1239|Firmicutes,4HUI1@91061|Bacilli,3FC41@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor MHFCBNDO_02863 543734.LCABL_29400 1.33e-105 305.0 COG3444@1|root,COG3444@2|Bacteria,1V41G@1239|Firmicutes,4HVY1@91061|Bacilli,3F9CU@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb MHFCBNDO_02864 543734.LCABL_29410 1.03e-92 271.0 COG2893@1|root,COG2893@2|Bacteria,1VBP2@1239|Firmicutes,4HW58@91061|Bacilli,3F89V@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component ahaA - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man MHFCBNDO_02865 543734.LCABL_29420 0.0 930.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQ6D@1239|Firmicutes,4HV5N@91061|Bacilli,3FA43@33958|Lactobacillaceae 91061|Bacilli K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - ko:K03491 - - - - ko00000,ko03000 - - - PTS_EIIA_2 MHFCBNDO_02866 543734.LCABL_29450 4.53e-203 562.0 COG0191@1|root,COG0191@2|Bacteria,1UXZF@1239|Firmicutes,4HTVJ@91061|Bacilli,3F99T@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II - - - - - - - - - - - - F_bP_aldolase MHFCBNDO_02867 543734.LCABL_29460 0.0 939.0 COG1070@1|root,COG1070@2|Bacteria,1VS9N@1239|Firmicutes,4HU27@91061|Bacilli,3F99X@33958|Lactobacillaceae 91061|Bacilli G FGGY family of carbohydrate kinases, C-terminal domain - - - - - - - - - - - - FGGY_C,FGGY_N MHFCBNDO_02868 543734.LCABL_29470 0.0 887.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HA1Q@91061|Bacilli,3F427@33958|Lactobacillaceae 91061|Bacilli G PTS system sugar-specific permease component - - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT MHFCBNDO_02869 543734.LCABL_29480 9.89e-64 194.0 COG3414@1|root,COG3414@2|Bacteria,1VIQT@1239|Firmicutes,4HYM1@91061|Bacilli,3F7ZQ@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_IIB MHFCBNDO_02870 543734.LCABL_29490 1.87e-102 297.0 COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes,4HJ5R@91061|Bacilli,3F9SN@33958|Lactobacillaceae 91061|Bacilli GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.200 ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_EIIA_2 MHFCBNDO_02871 543734.LCABL_29500 2.63e-206 570.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HT8R@91061|Bacilli,3F9GB@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II - - - - - - - - - - - - F_bP_aldolase MHFCBNDO_02872 543734.LCABL_29510 1.97e-173 484.0 COG2188@1|root,COG2188@2|Bacteria,1V724@1239|Firmicutes,4HVH9@91061|Bacilli,3F9M5@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain farR - - - - - - - - - - - GntR,UTRA MHFCBNDO_02873 543734.LCABL_29520 5.57e-115 329.0 COG1247@1|root,COG1247@2|Bacteria,1UIWB@1239|Firmicutes,4ISUG@91061|Bacilli 91061|Bacilli M Acetyltransferase (GNAT) domain - - - ko:K03828 - - - - ko00000,ko01000 - - - Acetyltransf_1 MHFCBNDO_02874 543734.LCABL_29530 6.18e-132 374.0 COG1695@1|root,COG1695@2|Bacteria,1VEN3@1239|Firmicutes,4HS7A@91061|Bacilli,3F6IE@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family laaE - - - - - - - - - - - PadR MHFCBNDO_02875 543734.LCABL_29540 0.0 996.0 COG0477@1|root,COG2814@2|Bacteria,1VRVX@1239|Firmicutes,4HV95@91061|Bacilli,3F4T2@33958|Lactobacillaceae 91061|Bacilli U the major facilitator superfamily chaT1 - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 MHFCBNDO_02876 543734.LCABL_29550 1.03e-111 321.0 COG0454@1|root,COG0454@2|Bacteria,1UHNV@1239|Firmicutes,4IS4R@91061|Bacilli,3F7IJ@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - - - - - - - - - - Acetyltransf_1 MHFCBNDO_02877 543734.LCABL_29560 4.94e-119 340.0 COG1335@1|root,COG1335@2|Bacteria,1VF7P@1239|Firmicutes,4HQSB@91061|Bacilli,3FC9Z@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family yveA - - - - - - - - - - - Isochorismatase MHFCBNDO_02878 568703.LGG_02642 7.48e-47 152.0 2E9Y3@1|root,3343R@2|Bacteria,1VFF0@1239|Firmicutes,4HPUY@91061|Bacilli,3F8BC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02879 543734.LCABL_29570 9.39e-74 221.0 2E9Y3@1|root,3343R@2|Bacteria,1VFF0@1239|Firmicutes,4HPUY@91061|Bacilli,3F8BC@33958|Lactobacillaceae 91061|Bacilli - - ps105 - - - - - - - - - - - - MHFCBNDO_02881 543734.LCABL_29590 1.73e-121 347.0 COG1476@1|root,COG1476@2|Bacteria,1VDCA@1239|Firmicutes,4HN0T@91061|Bacilli,3F7ZF@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - DUF1700,HTH_3,HTH_31 MHFCBNDO_02882 568703.LGG_02766 1.09e-154 435.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,3F4E3@33958|Lactobacillaceae 91061|Bacilli C glycerophosphoryl diester phosphodiesterase glpQ1 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD MHFCBNDO_02883 543734.LCABL_29620 1.12e-90 266.0 COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,4HH49@91061|Bacilli,3F6GQ@33958|Lactobacillaceae 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc MHFCBNDO_02884 543734.LCABL_29630 0.0 885.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HARC@91061|Bacilli,3FC76@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein ugpB - - ko:K05813 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - SBP_bac_8 MHFCBNDO_02885 543734.LCABL_29640 2.92e-192 533.0 COG0395@1|root,COG0395@2|Bacteria,1TR0I@1239|Firmicutes,4HB8C@91061|Bacilli,3F4Q5@33958|Lactobacillaceae 91061|Bacilli G ABC transporter permease ugpE - - ko:K05815 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - BPD_transp_1 MHFCBNDO_02886 543734.LCABL_29650 1.3e-210 583.0 COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,4HCD0@91061|Bacilli,3F464@33958|Lactobacillaceae 91061|Bacilli P ABC-type sugar transport systems, permease components - - - ko:K05814 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - BPD_transp_1 MHFCBNDO_02887 543734.LCABL_29660 7.33e-271 741.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HA50@91061|Bacilli,3FC3B@33958|Lactobacillaceae 91061|Bacilli E Belongs to the ABC transporter superfamily ugpC - 3.6.3.20 ko:K05816,ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.3 - - ABC_tran,TOBE_2 MHFCBNDO_02888 543734.LCABL_29670 0.0 927.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP nadC2 - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase MHFCBNDO_02889 543734.LCABL_29680 1.89e-139 393.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli,3F41F@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family pncA - - - - - - - - - - - Isochorismatase MHFCBNDO_02890 543734.LCABL_29690 1.1e-173 484.0 COG1051@1|root,COG4111@1|root,COG1051@2|Bacteria,COG4111@2|Bacteria,1UZ4E@1239|Firmicutes,4IPMJ@91061|Bacilli,3FBCZ@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX MHFCBNDO_02891 543734.LCABL_29700 1.39e-185 516.0 COG2367@1|root,COG2367@2|Bacteria,1VAJP@1239|Firmicutes 1239|Firmicutes V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 MHFCBNDO_02892 543734.LCABL_29710 1.12e-245 676.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,3F4XQ@33958|Lactobacillaceae 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family ykfB - 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N MHFCBNDO_02893 543734.LCABL_29720 2.19e-249 684.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,3F4K3@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase MHFCBNDO_02894 543734.LCABL_29730 4.79e-196 545.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,3F4T1@33958|Lactobacillaceae 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 MHFCBNDO_02895 543734.LCABL_29740 3.72e-210 582.0 COG1737@1|root,COG1737@2|Bacteria,1V26Y@1239|Firmicutes,4IQVW@91061|Bacilli,3FBJG@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS MHFCBNDO_02896 543734.LCABL_29750 1.67e-105 305.0 COG3444@1|root,COG3444@2|Bacteria,1V58C@1239|Firmicutes,4HJ9Y@91061|Bacilli,3F79W@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb MHFCBNDO_02897 543734.LCABL_29760 1.56e-192 536.0 COG3716@1|root,COG3716@2|Bacteria,1UZG2@1239|Firmicutes,4IQM5@91061|Bacilli,3F5FR@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA MHFCBNDO_02898 543734.LCABL_29770 2.51e-176 494.0 COG3715@1|root,COG3715@2|Bacteria,1UYP8@1239|Firmicutes,4IQM3@91061|Bacilli,3F5ZV@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component XK27_08455 - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor MHFCBNDO_02899 543734.LCABL_29780 7.17e-258 706.0 COG3568@1|root,COG3568@2|Bacteria,1U5BI@1239|Firmicutes,4HE49@91061|Bacilli,3F57I@33958|Lactobacillaceae 91061|Bacilli S endonuclease exonuclease phosphatase family protein - - - - - - - - - - - - Exo_endo_phos MHFCBNDO_02900 543734.LCABL_29790 1.26e-217 601.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F4FC@33958|Lactobacillaceae 91061|Bacilli S DHHA1 domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 MHFCBNDO_02901 568703.LGG_02785 9.2e-146 414.0 COG0500@1|root,COG2226@2|Bacteria,1TSAZ@1239|Firmicutes,4HIIG@91061|Bacilli,3F4S0@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase - - - - - - - - - - - - Methyltransf_11 MHFCBNDO_02902 543734.LCABL_29820 2.16e-68 207.0 COG2076@1|root,COG2076@2|Bacteria,1VEZX@1239|Firmicutes,4HKXB@91061|Bacilli,3F7D6@33958|Lactobacillaceae 91061|Bacilli U Multidrug resistance protein sugE - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res MHFCBNDO_02903 543734.LCABL_29870 2.48e-170 476.0 COG3393@1|root,COG3393@2|Bacteria,1TRN7@1239|Firmicutes,4HWMG@91061|Bacilli,3F84U@33958|Lactobacillaceae 91061|Bacilli S -acetyltransferase - - - - - - - - - - - - - MHFCBNDO_02904 543734.LCABL_29880 3.35e-121 345.0 COG0454@1|root,COG0456@2|Bacteria,1VEEJ@1239|Firmicutes,4HP6M@91061|Bacilli,3FBDP@33958|Lactobacillaceae 91061|Bacilli K FR47-like protein yfbM - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 MHFCBNDO_02905 543734.LCABL_29890 5.71e-121 345.0 COG0241@1|root,COG0241@2|Bacteria,1V6DW@1239|Firmicutes,4HJ23@91061|Bacilli 91061|Bacilli E HAD-hyrolase-like - - - - - - - - - - - - Hydrolase_like MHFCBNDO_02906 543734.LCABL_29900 1.19e-235 649.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,3F4EJ@33958|Lactobacillaceae 91061|Bacilli C nadph quinone reductase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 MHFCBNDO_02907 543734.LCABL_29910 1.33e-178 497.0 COG2365@1|root,COG2365@2|Bacteria,1V6Q5@1239|Firmicutes,4HJKY@91061|Bacilli,3F5X1@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family ptp1 - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 MHFCBNDO_02908 543734.LCABL_29930 7.95e-103 299.0 COG0454@1|root,COG0456@2|Bacteria,1V8AJ@1239|Firmicutes,4HPGU@91061|Bacilli,3F6YY@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 MHFCBNDO_02909 1136177.KCA1_2468 1.6e-55 177.0 COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4IPUS@91061|Bacilli 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 MHFCBNDO_02910 1231336.L248_1998 3.06e-157 451.0 COG0451@1|root,COG0451@2|Bacteria,1UEMD@1239|Firmicutes,4HDN7@91061|Bacilli,3F5S3@33958|Lactobacillaceae 91061|Bacilli GM Male sterility protein - - - - - - - - - - - - 3Beta_HSD,Epimerase MHFCBNDO_02911 568703.LGG_02795 1.87e-57 187.0 2DYM8@1|root,34AAZ@2|Bacteria,1VZP6@1239|Firmicutes,4HZAB@91061|Bacilli,3F99W@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02912 543734.LCABL_29940 1.35e-99 290.0 COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,4HIRW@91061|Bacilli,3F7FI@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain yiaC - - ko:K03826 - - - - ko00000,ko01000 - - - Acetyltransf_10,Acetyltransf_7 MHFCBNDO_02913 543734.LCABL_29950 3.43e-101 293.0 COG0454@1|root,COG0454@2|Bacteria,1UHUT@1239|Firmicutes,4HSN0@91061|Bacilli,3FBXG@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - ko:K03830 - - - - ko00000,ko01000 - - - Acetyltransf_10 MHFCBNDO_02914 543734.LCABL_29990 1.01e-105 305.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,3F3YX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase MHFCBNDO_02915 543734.LCABL_30000 6.32e-253 695.0 COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,4HEW7@91061|Bacilli,3F4CJ@33958|Lactobacillaceae 91061|Bacilli P Citrate transporter ysdE - - - - - - - - - - - CitMHS MHFCBNDO_02916 568703.LGG_02799 3.05e-91 278.0 29Q2V@1|root,30B3P@2|Bacteria,1U7H9@1239|Firmicutes,4IHDU@91061|Bacilli,3F9PB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02917 543734.LCABL_30020 0.0 889.0 COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli,3F541@33958|Lactobacillaceae 91061|Bacilli E Peptidase dimerisation domain dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 MHFCBNDO_02918 543734.LCABL_30030 0.0 1034.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 MHFCBNDO_02919 1423816.BACQ01000031_gene1333 4.2e-134 396.0 29Q2V@1|root,30B1G@2|Bacteria,1U7DH@1239|Firmicutes,4IH9F@91061|Bacilli,3F9FB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02920 543734.LCABL_30050 0.0 1123.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4JI@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - - - - - - - - - - - E1-E2_ATPase,Hydrolase MHFCBNDO_02921 543734.LCABL_30060 1.8e-99 288.0 COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HPDH@91061|Bacilli,3F7DR@33958|Lactobacillaceae 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family hsp3 - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 MHFCBNDO_02922 543734.LCABL_30070 2.35e-92 270.0 2F916@1|root,341CT@2|Bacteria,1VY7K@1239|Firmicutes,4HX4B@91061|Bacilli,3F70S@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn MHFCBNDO_02923 543734.LCABL_30080 1.7e-284 781.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,3F45X@33958|Lactobacillaceae 91061|Bacilli O serine protease htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 MHFCBNDO_02924 543734.LCABL_30090 4.32e-196 543.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,3F3S4@33958|Lactobacillaceae 91061|Bacilli S domain protein vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 MHFCBNDO_02925 543734.LCABL_30100 1.05e-182 509.0 COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,3F3PV@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycI - - - - - - - - - - - YycI MHFCBNDO_02926 543734.LCABL_30110 0.0 906.0 COG4863@1|root,COG4863@2|Bacteria,1V32Y@1239|Firmicutes,4HG2Q@91061|Bacilli,3F4HR@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycH - - - - - - - - - - - YycH MHFCBNDO_02927 543734.LCABL_30120 0.0 1214.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,3F45G@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 MHFCBNDO_02928 543734.LCABL_30130 3.03e-168 470.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,3F4FB@33958|Lactobacillaceae 91061|Bacilli K response regulator yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C MHFCBNDO_02929 543734.LCABL_30140 3.54e-156 438.0 COG0596@1|root,COG0596@2|Bacteria,1V02M@1239|Firmicutes,4HN2K@91061|Bacilli,3FBGC@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase family - - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 MHFCBNDO_02930 543734.LCABL_30150 0.0 895.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease arpJ - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - iSB619.SA_RS09465 BPD_transp_1,SBP_bac_3 MHFCBNDO_02931 543734.LCABL_30160 1.34e-297 811.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,3F46X@33958|Lactobacillaceae 91061|Bacilli E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04675 Arginosuc_synth MHFCBNDO_02932 543734.LCABL_30170 0.0 909.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,3F4PF@33958|Lactobacillaceae 91061|Bacilli E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 MHFCBNDO_02933 543734.LCABL_30180 3.77e-270 738.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4H9V2@91061|Bacilli,3F4FK@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) ybhE - - ko:K09963 - - - - ko00000 - - - DUF871 MHFCBNDO_02934 543734.LCABL_30190 9.09e-97 281.0 2DQNY@1|root,337UX@2|Bacteria,1VEZ0@1239|Firmicutes,4HPE2@91061|Bacilli,3F69F@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF3284) - - - - - - - - - - - - DUF3284 MHFCBNDO_02935 543734.LCABL_30200 1.76e-298 817.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F4VG@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane chbC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC MHFCBNDO_02936 543734.LCABL_30210 1.97e-168 470.0 COG2188@1|root,COG2188@2|Bacteria,1V54P@1239|Firmicutes,4IPPI@91061|Bacilli,3F5X0@33958|Lactobacillaceae 91061|Bacilli K UTRA gntR - - ko:K03489 - - - - ko00000,ko03000 - - - GntR,UTRA MHFCBNDO_02937 543734.LCABL_30220 5.86e-68 206.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F6GU@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit pts20B - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB MHFCBNDO_02938 543734.LCABL_30230 3.41e-71 214.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,3F6Z5@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose Cellobiose specific IIA subunit celC - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA MHFCBNDO_02939 543734.LCABL_30240 1.06e-139 393.0 COG1670@1|root,COG1670@2|Bacteria,1V3W1@1239|Firmicutes,4HH6A@91061|Bacilli,3F6G6@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain yokL3 - - - - - - - - - - - Acetyltransf_3 MHFCBNDO_02940 543734.LCABL_30250 7.49e-110 315.0 COG1051@1|root,COG1051@2|Bacteria,1V5NQ@1239|Firmicutes,4HH6Z@91061|Bacilli,3F674@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX MHFCBNDO_02941 543734.LCABL_30260 8.74e-116 332.0 COG4639@1|root,COG4639@2|Bacteria,1V2CI@1239|Firmicutes,4HGAU@91061|Bacilli,3FBXH@33958|Lactobacillaceae 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_33 MHFCBNDO_02942 543734.LCABL_30270 1.92e-147 415.0 COG1335@1|root,COG1335@2|Bacteria,1V7WN@1239|Firmicutes,4HIYX@91061|Bacilli,3F4WV@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family ycaC - - - - - - - - - - - Isochorismatase MHFCBNDO_02943 543734.LCABL_30280 0.0 904.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F5DA@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 MHFCBNDO_02944 543734.LCABL_30290 1.32e-272 747.0 COG2807@1|root,COG2807@2|Bacteria,1TP9R@1239|Firmicutes,4H9YZ@91061|Bacilli,3F52B@33958|Lactobacillaceae 91061|Bacilli P Transporter, major facilitator family protein yycB - - ko:K03449 - - - - ko00000,ko02000 2.A.1.17 - - MFS_1 MHFCBNDO_02945 543734.LCABL_30300 2.11e-220 608.0 COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,3F40K@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase iolS - - ko:K06607 - - - - ko00000,ko01000 - - - Aldo_ket_red MHFCBNDO_02946 543734.LCABL_30310 1.08e-84 249.0 COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes,4HIMF@91061|Bacilli,3F719@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF956) manO - - - - - - - - - - - DUF956 MHFCBNDO_02947 543734.LCABL_30320 1.73e-216 597.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component manN - - ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00278 R02630,R04076 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.3 - - EIID-AGA MHFCBNDO_02948 543734.LCABL_30330 1.57e-171 481.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli,3F3V5@33958|Lactobacillaceae 91061|Bacilli G PTS system manM - - ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277,M00278 R02630,R04076,R08366 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.3,4.A.6.1.4 - - EII-Sor MHFCBNDO_02949 543734.LCABL_30340 1.38e-228 630.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli,3F4PU@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component manL - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - EIIA-man,PTSIIB_sorb MHFCBNDO_02950 543734.LCABL_30350 1.97e-278 764.0 COG0477@1|root,COG2814@2|Bacteria,1UM0A@1239|Firmicutes,4ITNK@91061|Bacilli 91061|Bacilli EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 MHFCBNDO_02952 543734.LCABL_30360 1.03e-242 667.0 COG1396@1|root,COG1396@2|Bacteria,1V9XM@1239|Firmicutes,4HJUU@91061|Bacilli,3F79A@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K20373 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 MHFCBNDO_02953 543734.LCABL_30370 8.33e-193 536.0 COG1396@1|root,COG1396@2|Bacteria,1W2GY@1239|Firmicutes,4IGZ7@91061|Bacilli,3F8YW@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 MHFCBNDO_02954 543734.LCABL_30380 6.17e-204 565.0 COG1396@1|root,COG1396@2|Bacteria,1VD8E@1239|Firmicutes,4HMD2@91061|Bacilli,3F3QV@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins ywdE - - ko:K20375 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 MHFCBNDO_02956 543734.LCABL_30400 0.0 1006.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease XK27_05795 - - ko:K17073,ko:K17074 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.20 - - BPD_transp_1,SBP_bac_3 MHFCBNDO_02957 543734.LCABL_30410 3.81e-172 481.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - - ko:K17076 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.20 - - ABC_tran MHFCBNDO_02958 568703.LGG_02850 4.51e-41 136.0 2AHQJ@1|root,3182T@2|Bacteria,1U7RB@1239|Firmicutes,4IHNN@91061|Bacilli,3FA24@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02959 543734.LCABL_30430 2.01e-303 827.0 COG1653@1|root,COG1653@2|Bacteria,1TR68@1239|Firmicutes,4HX7S@91061|Bacilli 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 MHFCBNDO_02960 543734.LCABL_30440 1.33e-166 466.0 COG5523@1|root,COG5523@2|Bacteria,1VCPB@1239|Firmicutes,4HN1D@91061|Bacilli,3F69G@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF975) - - - - - - - - - - - - DUF975 MHFCBNDO_02961 1423732.BALS01000133_gene400 5.96e-53 168.0 COG4918@1|root,COG4918@2|Bacteria,1U783@1239|Firmicutes,4IH2X@91061|Bacilli,3F93I@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn MHFCBNDO_02962 543734.LCABL_30470 8.12e-69 208.0 298U1@1|root,2ZVY8@2|Bacteria,1W3JF@1239|Firmicutes,4I1SS@91061|Bacilli,3F7JE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02963 543734.LCABL_30480 8.68e-106 305.0 COG3402@1|root,COG3402@2|Bacteria,1VFTS@1239|Firmicutes,4HGMB@91061|Bacilli,3F6GM@33958|Lactobacillaceae 91061|Bacilli S Bacterial PH domain ydbS - - ko:K09167 - - - - ko00000 - - - bPH_2 MHFCBNDO_02964 543734.LCABL_30490 0.0 989.0 COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,3F3VB@33958|Lactobacillaceae 91061|Bacilli S Bacterial PH domain ydbT - - ko:K08981 - - - - ko00000 - - - bPH_2 MHFCBNDO_02965 543734.LCABL_30500 1.1e-185 516.0 COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,4HBQT@91061|Bacilli,3F8H5@33958|Lactobacillaceae 91061|Bacilli S AAA ATPase domain - - - - - - - - - - - - AAA_15,AAA_21,AAA_23 MHFCBNDO_02966 543734.LCABL_30510 7.92e-215 592.0 COG3001@1|root,COG3001@2|Bacteria,1U79A@1239|Firmicutes,4HAZS@91061|Bacilli,3F3RK@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase enzyme family - - - - - - - - - - - - Fructosamin_kin MHFCBNDO_02967 543734.LCABL_30520 1.09e-170 477.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran MHFCBNDO_02968 543734.LCABL_30530 0.0 915.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli,3F4HA@33958|Lactobacillaceae 91061|Bacilli P ABC transporter glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 MHFCBNDO_02969 543734.LCABL_30540 0.0 924.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli,3F4HA@33958|Lactobacillaceae 91061|Bacilli P ABC transporter glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 MHFCBNDO_02970 543734.LCABL_30550 9.37e-129 365.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,3F6YW@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain ydaF GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017198,GO:0018193,GO:0018209,GO:0019538,GO:0030920,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1990189 - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 MHFCBNDO_02971 543734.LCABL_30560 7.75e-138 390.0 COG1300@1|root,COG1300@2|Bacteria,1VFG7@1239|Firmicutes,4IRI6@91061|Bacilli,3F7WH@33958|Lactobacillaceae 91061|Bacilli S Stage II sporulation protein M - - - ko:K06384 - - - - ko00000 - - - SpoIIM MHFCBNDO_02972 1423816.BACQ01000031_gene1278 6.08e-181 508.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,3F59F@33958|Lactobacillaceae 91061|Bacilli S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 MHFCBNDO_02973 543734.LCABL_30590 1.76e-234 645.0 COG1721@1|root,COG1721@2|Bacteria,1VNZZ@1239|Firmicutes,4IGYV@91061|Bacilli,3F8YE@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 MHFCBNDO_02974 543734.LCABL_30610 0.0 1095.0 COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,3F5PB@33958|Lactobacillaceae 91061|Bacilli E Transglutaminase/protease-like homologues yebA - - - - - - - - - - - DUF4129,Transglut_core MHFCBNDO_02975 543734.LCABL_30620 4.08e-271 741.0 COG0438@1|root,COG0438@2|Bacteria,1TPHK@1239|Firmicutes,4HAXV@91061|Bacilli,3F5EZ@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 MHFCBNDO_02976 543734.LCABL_30630 1.34e-126 363.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HGH2@91061|Bacilli,3FBEM@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase thgA3 - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac MHFCBNDO_02977 543734.LCABL_30640 1.06e-186 519.0 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,3F3ZW@33958|Lactobacillaceae 91061|Bacilli G Sucrose-6F-phosphate phosphohydrolase - - 3.1.3.102,3.1.3.104,3.1.3.23 ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R00804,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 MHFCBNDO_02978 543734.LCABL_30650 0.0 890.0 COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,4HFM9@91061|Bacilli,3FBTC@33958|Lactobacillaceae 91061|Bacilli E Fumarase C C-terminus aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 MHFCBNDO_02979 543734.LCABL_30660 2.03e-147 414.0 COG4430@1|root,COG4430@2|Bacteria,1VCMU@1239|Firmicutes,4HN16@91061|Bacilli,3F68B@33958|Lactobacillaceae 91061|Bacilli S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA MHFCBNDO_02980 568703.LGG_02874 5.19e-62 193.0 28NY7@1|root,2ZBVG@2|Bacteria,1V2J3@1239|Firmicutes,4HMY0@91061|Bacilli,3F6EY@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2992) yjdF3 - - - - - - - - - - - DUF2992 MHFCBNDO_02981 543734.LCABL_30690 2.11e-271 744.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,3F4GN@33958|Lactobacillaceae 91061|Bacilli C Malic enzyme, NAD binding domain mae - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic MHFCBNDO_02982 543734.LCABL_30700 1.54e-291 799.0 COG3493@1|root,COG3493@2|Bacteria,1TR97@1239|Firmicutes,4HBS8@91061|Bacilli,3F61N@33958|Lactobacillaceae 91061|Bacilli C 2-hydroxycarboxylate transporter family malP - - ko:K11616 ko02020,map02020 - - - ko00000,ko00001 2.A.24.2 - - 2HCT MHFCBNDO_02983 543734.LCABL_30710 0.0 1001.0 COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,3F62P@33958|Lactobacillaceae 91061|Bacilli T Single cache domain 3 dpiB - 2.7.13.3 ko:K02476,ko:K11614 ko02020,map02020 M00490 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,SPOB_a,sCache_3_2 MHFCBNDO_02984 543734.LCABL_30720 3.66e-156 439.0 COG4565@1|root,COG4565@2|Bacteria,1V3PK@1239|Firmicutes,4HGXB@91061|Bacilli,3F702@33958|Lactobacillaceae 91061|Bacilli KT cheY-homologous receiver domain malR - - ko:K02475,ko:K11615 ko02020,map02020 M00490 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_11,Response_reg MHFCBNDO_02985 641146.HMPREF9020_01154 1.57e-300 819.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 MHFCBNDO_02986 543734.LCABL_30730 6.34e-194 539.0 COG2084@1|root,COG2084@2|Bacteria,1U5HC@1239|Firmicutes,4IF86@91061|Bacilli,3F5Y9@33958|Lactobacillaceae 91061|Bacilli I NAD binding domain of 6-phosphogluconate dehydrogenase - - - - - - - - - - - - NAD_binding_2 MHFCBNDO_02987 543734.LCABL_30740 3.6e-122 348.0 COG4283@1|root,COG4283@2|Bacteria,1TSF1@1239|Firmicutes,4HHG3@91061|Bacilli,3F6U6@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1706) M1-431 - - - - - - - - - - - DUF1706 MHFCBNDO_02990 543734.LCABL_30750 1.77e-83 247.0 29NYR@1|root,309WU@2|Bacteria,1U5V4@1239|Firmicutes,4IFIS@91061|Bacilli,3F6J0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_02991 543734.LCABL_30760 2.62e-283 777.0 COG0531@1|root,COG0531@2|Bacteria,1VTJD@1239|Firmicutes,4HTEM@91061|Bacilli,3FCAK@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yagE - - - - - - - - - - - AA_permease_2 MHFCBNDO_02992 543734.LCABL_30770 4.56e-215 594.0 COG0826@1|root,COG0826@2|Bacteria,1TPCZ@1239|Firmicutes,4HC7A@91061|Bacilli,3F4I6@33958|Lactobacillaceae 91061|Bacilli O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity - - - - - - - - - - - - - MHFCBNDO_02993 1423816.BACQ01000031_gene1259 1.37e-285 787.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system - - - - - - - - - - - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC MHFCBNDO_02994 1293597.BN147_01560 9.26e-52 169.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,3FC0X@33958|Lactobacillaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ptbA - 2.7.1.208 ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1 MHFCBNDO_02995 1423816.BACQ01000031_gene1258 6.71e-150 427.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,3F4SJ@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain - - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD MHFCBNDO_02997 543734.LCABL_31000 1.87e-217 600.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3V8@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs2 - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N MHFCBNDO_02998 543734.LCABL_31010 2.32e-233 640.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta - - - ko:K06889 - - - - ko00000 - - - DLH,FSH1,Hydrolase_4 MHFCBNDO_02999 543734.LCABL_31020 6.18e-238 653.0 COG0657@1|root,COG0657@2|Bacteria,1V2AW@1239|Firmicutes,4HU2V@91061|Bacilli,3F3N7@33958|Lactobacillaceae 91061|Bacilli I Carboxylesterase family lipA - - - - - - - - - - - Abhydrolase_3 MHFCBNDO_03000 543734.LCABL_31030 1.68e-275 753.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,3F448@33958|Lactobacillaceae 91061|Bacilli C mannitol-1-phosphate 5-dehydrogenase activity mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C MHFCBNDO_03001 543734.LCABL_31040 9.2e-101 292.0 COG4668@1|root,COG4668@2|Bacteria,1V77P@1239|Firmicutes,4HIM2@91061|Bacilli,3F6EP@33958|Lactobacillaceae 91061|Bacilli G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane mtlF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02798 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2 MHFCBNDO_03002 543734.LCABL_31050 0.0 1297.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,3F561@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB MHFCBNDO_03003 543734.LCABL_31060 0.0 1160.0 COG2213@1|root,COG2213@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,3F52S@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit mtlA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIC,PTS_IIB MHFCBNDO_03004 543734.LCABL_31070 2.05e-168 470.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,3F3NR@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso MHFCBNDO_03005 543734.LCABL_31080 3.86e-192 532.0 COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,3F49K@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 MHFCBNDO_03006 568703.LGG_02915 5.93e-59 181.0 29PY5@1|root,30AWK@2|Bacteria,1U774@1239|Firmicutes,4IH1Y@91061|Bacilli,3F926@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03007 568703.LGG_02916 6.72e-19 78.6 2BZTI@1|root,302JZ@2|Bacteria,1U8EV@1239|Firmicutes,4IICR@91061|Bacilli,3FAWN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03008 543734.LCABL_31120 2.5e-237 654.0 COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,4HG99@91061|Bacilli,3F5MV@33958|Lactobacillaceae 91061|Bacilli M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family hlyD3 - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 MHFCBNDO_03009 543734.LCABL_31130 2.9e-160 449.0 COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HFUH@91061|Bacilli,3F4CA@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran MHFCBNDO_03010 543734.LCABL_31140 3.59e-265 728.0 COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HBY9@91061|Bacilli,3F5FN@33958|Lactobacillaceae 91061|Bacilli V MacB-like periplasmic core domain yknZ - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD MHFCBNDO_03011 543734.LCABL_31160 0.0 1776.0 COG3209@1|root,COG3209@2|Bacteria,1VE5U@1239|Firmicutes,4ITNN@91061|Bacilli,3FBXI@33958|Lactobacillaceae 91061|Bacilli M Leucine rich repeats (6 copies) - - - - - - - - - - - - Gram_pos_anchor,LRR_5 MHFCBNDO_03012 97138.C820_01933 1.63e-244 683.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,36DZU@31979|Clostridiaceae 186801|Clostridia G Belongs to the glycosyl hydrolase 1 family bglA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 MHFCBNDO_03013 1545701.LACWKB10_0807 2.68e-248 705.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system arbF1 - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC MHFCBNDO_03014 97138.C820_01935 5.85e-58 189.0 COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,249XA@186801|Clostridia,36EEZ@31979|Clostridiaceae 186801|Clostridia K transcriptional antiterminator - - - ko:K03480,ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD MHFCBNDO_03015 568703.LGG_00464 2.8e-228 627.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_03016 1265845.PWEIH_06876 1.9e-12 68.6 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,26J6R@186820|Listeriaceae 91061|Bacilli K antiterminator licT - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD MHFCBNDO_03017 543734.LCABL_31170 5.44e-256 702.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,4HC8K@91061|Bacilli,3F4E4@33958|Lactobacillaceae 91061|Bacilli C dehydrogenase ypjH - - ko:K08317 - - - - ko00000,ko01000 - - - Fe-ADH MHFCBNDO_03018 543734.LCABL_31180 1.53e-288 788.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,3FC42@33958|Lactobacillaceae 91061|Bacilli E Peptidase family M20/M25/M40 amd - - - - - - - - - - - M20_dimer,Peptidase_M20 MHFCBNDO_03019 543734.LCABL_31190 1.48e-104 303.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,3F706@33958|Lactobacillaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 MHFCBNDO_03020 543734.LCABL_31200 3.8e-175 489.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,3F4XE@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter labL - - - - - - - - - - - ThrE MHFCBNDO_03022 543734.LCABL_31220 0.0 1248.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,3F454@33958|Lactobacillaceae 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc MHFCBNDO_03023 543734.LCABL_31230 0.0 879.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,3F3WA@33958|Lactobacillaceae 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N MHFCBNDO_03025 543734.LCABL_31240 1.42e-170 477.0 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli,3F5WG@33958|Lactobacillaceae 91061|Bacilli S R3H domain protein jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H MHFCBNDO_03026 543734.LCABL_31250 4.53e-179 501.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,3F3SD@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP MHFCBNDO_03027 543734.LCABL_31260 2.99e-77 233.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,3F6GS@33958|Lactobacillaceae 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P MHFCBNDO_03028 543734.LCABL_31270 3.26e-23 88.6 COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,3F81W@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 MHFCBNDO_03032 1158614.I592_04174 9.85e-05 44.7 2DK2G@1|root,3088P@2|Bacteria,1U30M@1239|Firmicutes,4ICQK@91061|Bacilli,4B5DJ@81852|Enterococcaceae 91061|Bacilli S Ribbon-helix-helix protein, copG family - - - - - - - - - - - - RHH_1 MHFCBNDO_03034 1423732.BALS01000076_gene2137 9.57e-286 782.0 COG0790@1|root,COG0790@2|Bacteria,1UHSY@1239|Firmicutes,4IS8P@91061|Bacilli,3F8F0@33958|Lactobacillaceae 91061|Bacilli S COG0790 FOG TPR repeat, SEL1 subfamily - - - - - - - - - - - - - MHFCBNDO_03036 543734.LCABL_06050 0.0 1621.0 COG0358@1|root,COG4227@1|root,COG0358@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,4HKTX@91061|Bacilli,3F8MI@33958|Lactobacillaceae 91061|Bacilli L Protein of unknown function (DUF3991) - - - - - - - - - - - - DUF3991,Toprim_2 MHFCBNDO_03037 543734.LCABL_06080 1.3e-24 94.7 2ED72@1|root,3373P@2|Bacteria,1W17P@1239|Firmicutes,4HXZS@91061|Bacilli,3FADZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03038 1423732.BALS01000076_gene2134 5.71e-47 152.0 2ED72@1|root,3373P@2|Bacteria,1W17P@1239|Firmicutes,4HXZS@91061|Bacilli,3FADZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03039 1423816.BACQ01000066_gene2559 2.45e-23 89.0 293FZ@1|root,2ZQYB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - MHFCBNDO_03040 1423732.BALS01000076_gene2132 5.33e-103 298.0 2DUJT@1|root,33R01@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - MHFCBNDO_03042 543734.LCABL_06130 8.5e-95 277.0 2F273@1|root,33V59@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - MHFCBNDO_03043 1423732.BALS01000076_gene2129 5.34e-192 535.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HK7D@91061|Bacilli,3FC9V@33958|Lactobacillaceae 91061|Bacilli F DNA/RNA non-specific endonuclease - - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 MHFCBNDO_03045 1033837.WANG_1733 2.31e-105 304.0 COG3293@1|root,COG3293@2|Bacteria,1VTEC@1239|Firmicutes,4HUXQ@91061|Bacilli,3F62D@33958|Lactobacillaceae 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 MHFCBNDO_03046 203123.OEOE_0334 3.58e-76 226.0 COG3293@1|root,COG3293@2|Bacteria,1VW4T@1239|Firmicutes,4HWBF@91061|Bacilli,4AYJV@81850|Leuconostocaceae 91061|Bacilli L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 MHFCBNDO_03047 1229758.C270_03955 1.21e-123 371.0 COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes,4HFAV@91061|Bacilli,4AXBM@81850|Leuconostocaceae 91061|Bacilli V type I restriction modification DNA specificity domain protein hsdS - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S MHFCBNDO_03048 1423816.BACQ01000038_gene1594 0.0 1060.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli,3F4HM@33958|Lactobacillaceae 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase MHFCBNDO_03049 913848.AELK01000078_gene1665 0.0 2023.0 COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4HB5A@91061|Bacilli,3F50Q@33958|Lactobacillaceae 91061|Bacilli V Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoR124_C,HSDR_N,ResIII MHFCBNDO_03050 405566.lhv_1905 6.02e-217 598.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,3F4VD@33958|Lactobacillaceae 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family mccA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00609 R00897,R03601,R04859,R10305 RC00020,RC00069,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02385 PALP MHFCBNDO_03051 326425.lhe_0318 2.93e-279 764.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,3F3Y2@33958|Lactobacillaceae 91061|Bacilli E cystathionine mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP MHFCBNDO_03052 326425.lhe_0319 2.99e-122 349.0 COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli,3F63E@33958|Lactobacillaceae 91061|Bacilli E Bacterial transferase hexapeptide (six repeats) cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,SATase_N MHFCBNDO_03053 203123.OEOE_0334 3.58e-76 226.0 COG3293@1|root,COG3293@2|Bacteria,1VW4T@1239|Firmicutes,4HWBF@91061|Bacilli,4AYJV@81850|Leuconostocaceae 91061|Bacilli L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 MHFCBNDO_03054 1033837.WANG_1733 4.39e-76 229.0 COG3293@1|root,COG3293@2|Bacteria,1VTEC@1239|Firmicutes,4HUXQ@91061|Bacilli,3F62D@33958|Lactobacillaceae 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 MHFCBNDO_03055 1423732.BALS01000131_gene404 7.73e-200 555.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,3F4K2@33958|Lactobacillaceae 91061|Bacilli U sugar transport glcU GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659 - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport MHFCBNDO_03056 272623.L141634 2.74e-21 87.8 COG2890@1|root,COG2890@2|Bacteria,1UJ7I@1239|Firmicutes,4IT3Q@91061|Bacilli,1YBNP@1357|Lactococcus 91061|Bacilli J Putative rRNA methylase - - - - - - - - - - - - rRNA_methylase MHFCBNDO_03057 1122149.BACN01000095_gene1995 3.37e-48 154.0 COG3293@1|root,COG3293@2|Bacteria,1U5ZT@1239|Firmicutes,4IFNT@91061|Bacilli,3F6RW@33958|Lactobacillaceae 91061|Bacilli L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 MHFCBNDO_03058 220668.lp_3482 7.7e-62 201.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli,3F3Q9@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg MHFCBNDO_03059 220668.lp_3483 0.0 1305.0 COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,4HANW@91061|Bacilli,3F4EI@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 2 family lacL - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N MHFCBNDO_03060 1423732.BALS01000088_gene2037 1.35e-237 652.0 COG3250@1|root,COG3250@2|Bacteria,1TRVA@1239|Firmicutes,4HFMH@91061|Bacilli,3F51Z@33958|Lactobacillaceae 91061|Bacilli G beta-galactosidase lacM - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N MHFCBNDO_03061 1423732.BALS01000088_gene2038 5.64e-255 698.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,3F3RU@33958|Lactobacillaceae 91061|Bacilli G alpha-galactosidase melA GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009987,GO:0010033,GO:0015925,GO:0016043,GO:0016052,GO:0016787,GO:0016798,GO:0022607,GO:0042221,GO:0043933,GO:0044085,GO:0044238,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901545,GO:1901575,GO:1901700 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase MHFCBNDO_03062 203123.OEOE_0334 3.58e-76 226.0 COG3293@1|root,COG3293@2|Bacteria,1VW4T@1239|Firmicutes,4HWBF@91061|Bacilli,4AYJV@81850|Leuconostocaceae 91061|Bacilli L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 MHFCBNDO_03063 1033837.WANG_1733 9.4e-105 303.0 COG3293@1|root,COG3293@2|Bacteria,1VTEC@1239|Firmicutes,4HUXQ@91061|Bacilli,3F62D@33958|Lactobacillaceae 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 MHFCBNDO_03064 1133569.AHYZ01000003_gene559 8.63e-218 608.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,3F3WN@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA polymerase type-Y family polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH MHFCBNDO_03065 1133569.AHYZ01000177_gene359 5.23e-36 121.0 29PHS@1|root,30AFX@2|Bacteria,1U6KZ@1239|Firmicutes,4IGDS@91061|Bacilli,3F84Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03066 1423732.BALS01000046_gene2623 0.0 883.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HBZF@91061|Bacilli,3FC6T@33958|Lactobacillaceae 91061|Bacilli C Pyridine nucleotide-disulfide oxidoreductase - - 1.8.1.7 ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim MHFCBNDO_03067 525318.HMPREF0497_2983 1.51e-77 230.0 COG3293@1|root,COG3293@2|Bacteria,1U5ZT@1239|Firmicutes,4IFNT@91061|Bacilli,3F6RW@33958|Lactobacillaceae 91061|Bacilli L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 MHFCBNDO_03068 543734.LCABL_21340 2.29e-81 242.0 COG3293@1|root,COG3293@2|Bacteria,1VTEC@1239|Firmicutes,4HUXQ@91061|Bacilli,3F62D@33958|Lactobacillaceae 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 MHFCBNDO_03069 1423732.BALS01000046_gene2619 3.82e-65 204.0 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,4HGSR@91061|Bacilli,3FBSG@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 MHFCBNDO_03070 543734.LCABL_07260 2.08e-207 573.0 COG3711@1|root,COG3711@2|Bacteria,1VS0S@1239|Firmicutes,4HTFM@91061|Bacilli,3F6AX@33958|Lactobacillaceae 91061|Bacilli K PRD domain lacT - - ko:K02531 - - - - ko00000,ko03000 - - - CAT_RBD,PRD MHFCBNDO_03071 1423816.BACQ01000070_gene2576 0.0 1099.0 COG1440@1|root,COG1455@1|root,COG1440@2|Bacteria,COG1455@2|Bacteria,1TQPV@1239|Firmicutes,4HC9I@91061|Bacilli,3F4DV@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase system, EIIC lacE GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016310,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704 2.7.1.207 ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00281 R04393 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1 - - PTS_EIIC,PTS_IIB MHFCBNDO_03072 543734.LCABL_07280 0.0 983.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,3FC7B@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family lacG GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.21,3.2.1.85,3.2.1.86 ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03256,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 MHFCBNDO_03073 1423732.BALS01000046_gene2613 2.65e-67 204.0 COG1447@1|root,COG1447@2|Bacteria,1V87W@1239|Firmicutes,4HJSY@91061|Bacilli,3FCDI@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit lacF - 2.7.1.196,2.7.1.205,2.7.1.207 ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 - - PTS_IIA MHFCBNDO_03074 1033837.WANG_1733 6.89e-107 308.0 COG3293@1|root,COG3293@2|Bacteria,1VTEC@1239|Firmicutes,4HUXQ@91061|Bacilli,3F62D@33958|Lactobacillaceae 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 MHFCBNDO_03075 203123.OEOE_0334 2.15e-77 229.0 COG3293@1|root,COG3293@2|Bacteria,1VW4T@1239|Firmicutes,4HWBF@91061|Bacilli,4AYJV@81850|Leuconostocaceae 91061|Bacilli L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 MHFCBNDO_03076 1158601.I585_03571 2.08e-278 805.0 COG1221@1|root,COG3933@1|root,COG1221@2|Bacteria,COG3933@2|Bacteria,1VSHE@1239|Firmicutes,4HB6T@91061|Bacilli,4AZY1@81852|Enterococcaceae 91061|Bacilli K Sigma-54 interaction domain levR - - - - - - - - - - - EIIA-man,PRD,Sigma54_activat MHFCBNDO_03077 1423775.BAMN01000001_gene2657 1.11e-107 332.0 COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,3F4R8@33958|Lactobacillaceae 91061|Bacilli K Sigma-54 factor, core binding domain rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD MHFCBNDO_03078 1158612.I580_03145 1.55e-28 108.0 COG2893@1|root,COG2893@2|Bacteria,1VEDV@1239|Firmicutes,4HX8V@91061|Bacilli,4B2T8@81852|Enterococcaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.203 ko:K17464 ko00030,ko01120,ko02060,map00030,map01120,map02060 M00610 R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.17 - - EIIA-man MHFCBNDO_03079 1005994.GTGU_04455 5.73e-63 197.0 COG3444@1|root,COG3444@2|Bacteria,1P9P7@1224|Proteobacteria,1RYVC@1236|Gammaproteobacteria 1236|Gammaproteobacteria G PTS system - - 2.7.1.203 ko:K17465 ko00030,ko01120,ko02060,map00030,map01120,map02060 M00610 R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.17 - - PTSIIB_sorb MHFCBNDO_03080 1140002.I570_00451 4.8e-130 374.0 COG3715@1|root,COG3715@2|Bacteria,1V07Y@1239|Firmicutes,4IQM7@91061|Bacilli,4B1J9@81852|Enterococcaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K17466 ko00030,ko01120,ko02060,map00030,map01120,map02060 M00610 R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1.17 - - EII-Sor MHFCBNDO_03081 1158612.I580_03148 1.68e-134 388.0 COG3716@1|root,COG3716@2|Bacteria,1TS9D@1239|Firmicutes,4HH0J@91061|Bacilli,4AZZG@81852|Enterococcaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K17467 ko00030,ko01120,ko02060,map00030,map01120,map02060 M00610 R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1.17 - - EIID-AGA MHFCBNDO_03082 543734.LCABL_28920 1.24e-259 712.0 COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,4HC3U@91061|Bacilli,3F4MN@33958|Lactobacillaceae 91061|Bacilli H L-seryl-tRNA selenium transferase selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - SelA MHFCBNDO_03083 543734.LCABL_28910 1.55e-174 487.0 2DBAP@1|root,2Z844@2|Bacteria,1TQX7@1239|Firmicutes,4HABQ@91061|Bacilli,3F5QS@33958|Lactobacillaceae 91061|Bacilli S KDGP aldolase - - 4.1.2.14 ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 M00061,M00631 R05605 RC00307,RC00435 ko00000,ko00001,ko00002,ko01000 - - - KDGP_aldolase MHFCBNDO_03084 568703.LGG_00464 1.17e-156 442.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_03085 525318.HMPREF0497_2982 3.35e-32 114.0 COG3293@1|root,COG3293@2|Bacteria,1U67N@1239|Firmicutes,4IFY7@91061|Bacilli,3F79E@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_2 MHFCBNDO_03086 203123.OEOE_0334 2.15e-77 229.0 COG3293@1|root,COG3293@2|Bacteria,1VW4T@1239|Firmicutes,4HWBF@91061|Bacilli,4AYJV@81850|Leuconostocaceae 91061|Bacilli L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 MHFCBNDO_03087 568703.LGG_00435 1.24e-06 49.3 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_03088 220668.lp_2651 2.61e-51 174.0 COG2188@1|root,COG2188@2|Bacteria,1UIXK@1239|Firmicutes,4ISVV@91061|Bacilli,3F68S@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA MHFCBNDO_03089 1400520.LFAB_14935 1.24e-86 257.0 COG3444@1|root,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4HI37@91061|Bacilli,3F5PA@33958|Lactobacillaceae 91061|Bacilli K PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277,M00287 R02630,R08366,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.6.1.4,4.A.6.1.5 - - GntR,PTSIIB_sorb MHFCBNDO_03090 220668.lp_2649 6.34e-154 436.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4HC0V@91061|Bacilli,3F4YT@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 M00277,M00287 R08366,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1.4,4.A.6.1.5 - - EII-Sor MHFCBNDO_03091 1423775.BAMN01000002_gene1999 3.17e-148 422.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HD65@91061|Bacilli,3F4YA@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component agaD - - ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277,M00287 R02630,R08366,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.4,4.A.6.1.5 - - EIID-AGA MHFCBNDO_03092 1400520.LFAB_14950 9.6e-40 137.0 COG2893@1|root,COG2893@2|Bacteria,1VC2D@1239|Firmicutes,4HXQW@91061|Bacilli,3FBI6@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - - - - - - - - - - - EIIA-man MHFCBNDO_03094 568703.LGG_00435 1.82e-227 625.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - rve MHFCBNDO_03095 568703.LGG_00434 0.0 1108.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,3F4B7@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolase family 3 N terminal domain nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - DUF4309,Glyco_hydro_3 MHFCBNDO_03098 1423755.BAML01000037_gene1522 9.23e-107 317.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HCBZ@91061|Bacilli,3F4QA@33958|Lactobacillaceae 91061|Bacilli D CobQ CobB MinD ParA nucleotide binding domain protein soj - - - - - - - - - - - AAA_31 MHFCBNDO_03099 944562.HMPREF9102_2161 1.02e-106 324.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,3F55E@33958|Lactobacillaceae 91061|Bacilli S Replication initiator protein A repA - - - - - - - - - - - RepA_N MHFCBNDO_03100 797515.HMPREF9103_02001 1.22e-79 237.0 2BAF6@1|root,323VN@2|Bacteria,1UQAF@1239|Firmicutes,4IFGF@91061|Bacilli,3F6F2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03101 908339.HMPREF9265_1755 0.0 959.0 COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,4H9ZN@91061|Bacilli,3F4S3@33958|Lactobacillaceae 91061|Bacilli U TraM recognition site of TraD and TraG traK - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf MHFCBNDO_03102 220668.45723577 1.82e-102 297.0 2AC4N@1|root,311NX@2|Bacteria,1U59I@1239|Firmicutes,4IF0X@91061|Bacilli,3F59S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03103 908339.HMPREF9265_1412 5.77e-123 353.0 29UXR@1|root,30GAH@2|Bacteria,1UFKJ@1239|Firmicutes,4IEU2@91061|Bacilli,3F46S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03104 1045004.OKIT_0530 2.59e-277 758.0 COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1VW67@1239|Firmicutes,4HWSY@91061|Bacilli 91061|Bacilli M CHAP domain - - - - - - - - - - - - Amidase_5,Beta-lactamase2,CHAP,NLPC_P60 MHFCBNDO_03105 220668.45723581 0.0 869.0 COG4499@1|root,COG4499@2|Bacteria,1V1PS@1239|Firmicutes,4HGKF@91061|Bacilli,3F450@33958|Lactobacillaceae 91061|Bacilli S WXG100 protein secretion system (Wss), protein YukC - - - - - - - - - - - - YukC MHFCBNDO_03106 1291743.LOSG293_220160 0.0 1296.0 COG3451@1|root,COG3451@2|Bacteria,1TS2J@1239|Firmicutes,4HYWU@91061|Bacilli,3F3NC@33958|Lactobacillaceae 91061|Bacilli U type IV secretory pathway VirB4 - - - - - - - - - - - - DUF87 MHFCBNDO_03107 1291743.LOSG293_220150 4.48e-152 427.0 2ECAZ@1|root,3369B@2|Bacteria,1VEP6@1239|Firmicutes,4HQSU@91061|Bacilli,3F5SZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03108 1291743.LOSG293_220140 8.94e-70 211.0 2F48Y@1|root,33WZQ@2|Bacteria,1VVYR@1239|Firmicutes,4HW55@91061|Bacilli,3F6NH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03109 1291743.LOSG293_220130 6.31e-68 206.0 2BZG5@1|root,309WK@2|Bacteria,1U5UW@1239|Firmicutes,4IFIG@91061|Bacilli,3F6IN@33958|Lactobacillaceae 91061|Bacilli S Cag pathogenicity island, type IV secretory system - - - - - - - - - - - - T4SS_CagC MHFCBNDO_03110 797515.HMPREF9103_01296 3.99e-134 381.0 29NNG@1|root,309KE@2|Bacteria,1U59R@1239|Firmicutes,4IF1A@91061|Bacilli,3F5AZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03111 797515.HMPREF9103_01297 7.08e-68 205.0 29PC9@1|root,30AAH@2|Bacteria,1U6EB@1239|Firmicutes,4IG63@91061|Bacilli,3F7QB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03112 1291743.LOSG293_220100 0.0 1255.0 COG0507@1|root,COG0507@2|Bacteria,1VQWC@1239|Firmicutes,4HD6B@91061|Bacilli,3F4DP@33958|Lactobacillaceae 91061|Bacilli L MobA MobL family protein traA - - - - - - - - - - - MobA_MobL MHFCBNDO_03113 1423734.JCM14202_2802 3.41e-37 125.0 29P8B@1|root,30A6E@2|Bacteria,1U69C@1239|Firmicutes,4IG0H@91061|Bacilli,3F7CM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03114 1291743.LOSG293_220080 2.51e-55 173.0 2EJES@1|root,33D5R@2|Bacteria,1VKZC@1239|Firmicutes,4HRGI@91061|Bacilli,3F6Y2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03115 1423780.LOT_2224 3.89e-112 322.0 2EHZR@1|root,33BR8@2|Bacteria,1VQDB@1239|Firmicutes,4HRJT@91061|Bacilli,3F5IT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - PemK_toxin MHFCBNDO_03116 1045004.OKIT_0519 6.94e-59 182.0 COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,4HR7A@91061|Bacilli 91061|Bacilli L Addiction module antitoxin, RelB DinJ family - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB MHFCBNDO_03117 1122149.BACN01000104_gene2008 2.44e-36 124.0 COG3293@1|root,COG3293@2|Bacteria,1U5ZT@1239|Firmicutes,4IFNT@91061|Bacilli,3F6RW@33958|Lactobacillaceae 91061|Bacilli L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 MHFCBNDO_03119 387344.LVIS_A09 2.66e-112 338.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,3F55E@33958|Lactobacillaceae 91061|Bacilli S Replication initiator protein A repA - - - - - - - - - - - RepA_N MHFCBNDO_03120 1140001.I571_03057 6.29e-126 369.0 COG1192@1|root,COG1192@2|Bacteria,1V1YN@1239|Firmicutes,4IQV7@91061|Bacilli,4B1NG@81852|Enterococcaceae 91061|Bacilli D Cellulose biosynthesis protein BcsQ - - - - - - - - - - - - AAA_31 MHFCBNDO_03122 224308.BSU19010 4.82e-08 57.8 COG4282@1|root,COG4282@2|Bacteria,1W2DK@1239|Firmicutes,4I1HJ@91061|Bacilli,1ZHYP@1386|Bacillus 91061|Bacilli G SMI1 / KNR4 family yokH - - - - - - - - - - - SMI1_KNR4 MHFCBNDO_03123 543734.LCABL_00300 1.54e-39 145.0 COG3409@1|root,COG3409@2|Bacteria,1TPV1@1239|Firmicutes,4HCRA@91061|Bacilli,3F5J4@33958|Lactobacillaceae 91061|Bacilli M peptidoglycan-binding domain-containing protein ybfG - - - - - - - - - - - DUF1906,PG_binding_1 MHFCBNDO_03125 936140.AEOT01000026_gene774 1.56e-37 143.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts4ABC - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC MHFCBNDO_03126 220668.lp_3521 2.85e-56 189.0 COG1737@1|root,COG1737@2|Bacteria,1TPIX@1239|Firmicutes,4HBJA@91061|Bacilli,3F5WQ@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family yleF - - - - - - - - - - - HTH_6,SIS MHFCBNDO_03127 862514.HMPREF0623_1438 8.19e-119 350.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,3F4T1@33958|Lactobacillaceae 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 MHFCBNDO_03128 1074451.CRL705_1100 6.83e-98 301.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4HAHJ@91061|Bacilli,3FB4D@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) - - 4.2.1.126 ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - DUF871 MHFCBNDO_03129 1122147.AUEH01000031_gene2614 2e-278 769.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system - - 2.7.1.211 ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIB,PTS_EIIC MHFCBNDO_03130 1545702.LACWKB8_1495 1.88e-139 402.0 COG0627@1|root,COG0627@2|Bacteria,1V856@1239|Firmicutes,4HVCY@91061|Bacilli,3F5Y5@33958|Lactobacillaceae 91061|Bacilli S Putative esterase - - - - - - - - - - - - Esterase MHFCBNDO_03133 1291743.LOSG293_360100 1.51e-173 483.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,3F4IY@33958|Lactobacillaceae 91061|Bacilli C nitroreductase nfrA - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase MHFCBNDO_03135 1400520.LFAB_15070 2.06e-57 192.0 COG2115@1|root,COG2115@2|Bacteria,1TQW2@1239|Firmicutes,4H9WG@91061|Bacilli,3F5ME@33958|Lactobacillaceae 91061|Bacilli G Belongs to the xylose isomerase family xylA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - AP_endonuc_2 MHFCBNDO_03136 1267003.KB911382_gene2077 6.94e-92 288.0 COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,4HDE3@91061|Bacilli,3F540@33958|Lactobacillaceae 91061|Bacilli GK ROK family xylR - - - - - - - - - - - HTH_24,MarR,ROK MHFCBNDO_03137 272563.CD630_30670 2.11e-38 133.0 COG2893@1|root,COG2893@2|Bacteria,1VI8D@1239|Firmicutes,24QFY@186801|Clostridia 186801|Clostridia G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man MHFCBNDO_03138 272563.CD630_30680 4.11e-83 248.0 COG3444@1|root,COG3444@2|Bacteria,1V46G@1239|Firmicutes,24I8X@186801|Clostridia 186801|Clostridia G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb MHFCBNDO_03139 1158610.UC3_00353 1.46e-148 423.0 COG3716@1|root,COG3716@2|Bacteria,1UZYR@1239|Firmicutes,4HUBE@91061|Bacilli,4AZXZ@81852|Enterococcaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA MHFCBNDO_03140 272563.CD630_30700 1.27e-144 412.0 COG3715@1|root,COG3715@2|Bacteria,1UYP8@1239|Firmicutes,24D6U@186801|Clostridia 186801|Clostridia G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor MHFCBNDO_03141 272563.CD630_30710 0.0 1021.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia 186801|Clostridia G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.177 ko:K01811 - - - - ko00000,ko01000 - GH31 - DUF5110,Glyco_hydro_31 MHFCBNDO_03143 1291743.LOSG293_350150 3.62e-56 185.0 COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,4HEX8@91061|Bacilli,3F5HS@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_5,DDE_Tnp_1 MHFCBNDO_03145 1158601.I585_03520 1.87e-31 119.0 COG1476@1|root,COG1476@2|Bacteria,1V8IM@1239|Firmicutes,4HQD4@91061|Bacilli,4B55D@81852|Enterococcaceae 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 MHFCBNDO_03147 1423743.JCM14108_1171 3.78e-41 152.0 COG1061@1|root,COG1061@2|Bacteria,1TS5R@1239|Firmicutes,4HCVA@91061|Bacilli 91061|Bacilli L Type III restriction protein res subunit XK27_08510 - - - - - - - - - - - Helicase_C,ResIII MHFCBNDO_03148 1423816.BACQ01000047_gene1751 2.35e-212 626.0 COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1TS5R@1239|Firmicutes,4HCVA@91061|Bacilli 91061|Bacilli L Type III restriction protein res subunit XK27_08510 - - - - - - - - - - - Helicase_C,ResIII MHFCBNDO_03149 568703.LGG_00022 0.0 907.0 COG3039@1|root,COG3039@2|Bacteria,1TRUS@1239|Firmicutes,4HCCQ@91061|Bacilli,3F5ZY@33958|Lactobacillaceae 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2,DUF772 MHFCBNDO_03150 1138822.PL11_10335 0.0 1693.0 COG3421@1|root,COG3421@2|Bacteria,1TRVK@1239|Firmicutes,4HAVG@91061|Bacilli,3F61Y@33958|Lactobacillaceae 91061|Bacilli L Type III restriction enzyme, res subunit sthIR - 3.1.21.5 ko:K01156 - - - - ko00000,ko01000,ko02048 - - - ResIII MHFCBNDO_03151 1291743.LOSG293_220290 2.08e-263 744.0 COG2189@1|root,COG2189@2|Bacteria,1TR8A@1239|Firmicutes,4HBP1@91061|Bacilli,3F504@33958|Lactobacillaceae 91061|Bacilli L DNA methylase - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase,TypeIII_RM_meth MHFCBNDO_03152 1133569.AHYZ01000177_gene359 1.84e-34 117.0 29PHS@1|root,30AFX@2|Bacteria,1U6KZ@1239|Firmicutes,4IGDS@91061|Bacilli,3F84Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03153 1400520.LFAB_17305 2.83e-244 674.0 COG4227@1|root,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,4HKTX@91061|Bacilli,3F5I0@33958|Lactobacillaceae 91061|Bacilli L Psort location Cytoplasmic, score - - - - - - - - - - - - - MHFCBNDO_03154 797515.HMPREF9103_01821 7.27e-42 137.0 29P8A@1|root,30A6D@2|Bacteria,1U69B@1239|Firmicutes,4IG0G@91061|Bacilli,3F7CJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - MHFCBNDO_03155 1291743.LOSG293_220250 0.0 1341.0 COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,3F4W6@33958|Lactobacillaceae 91061|Bacilli L This gene contains a nucleotide ambiguity which may be the result of a sequencing error traI - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim,Toprim_Crpt,zf-C4_Topoisom MHFCBNDO_03156 1423816.BACQ01000038_gene1588 1.71e-86 255.0 29NXD@1|root,309VH@2|Bacteria,1U5SV@1239|Firmicutes,4IFGT@91061|Bacilli,3F6FI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - ## 2859 queries scanned ## Total time (seconds): 1.951359510421753 ## Rate: 1465.13 q/s