GCA_013267115.1 - 11 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaDCGKMBIL_1 (original name was: gnl|Prokka|DCGKMBIL_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	transAT-PKS,NRPS,T3PKS,PKS-like	13,892	128,664	bacillaene	Polyketide+NRP	100%

gnlProkkaDCGKMBIL_2 (original name was: gnl|Prokka|DCGKMBIL_2)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	NRP-metallophore,NRPS	5,152	56,929	bacillibactin	NRP	100%
Region 2.2	CDPS	336,004	356,750	pulcherriminic acid	Other	100%

gnlProkkaDCGKMBIL_3 (original name was: gnl|Prokka|DCGKMBIL_3)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	T3PKS	122,953	158,379	1-carbapen-2-em-3-carboxylic acid	Other	16%

gnlProkkaDCGKMBIL_4 (original name was: gnl|Prokka|DCGKMBIL_4)

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	lanthipeptide-class-ii	1	21,341

gnlProkkaDCGKMBIL_23 (original name was: gnl|Prokka|DCGKMBIL_23)

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	other	190,700	232,118	bacilysin	Other	100%
Region 22.2	sactipeptide	234,859	256,470	subtilosin A	RiPP:Thiopeptide	100%

gnlProkkaDCGKMBIL_26 (original name was: gnl|Prokka|DCGKMBIL_26)

Region	Type	From	To	Most similar known cluster		Similarity
Region 24.1	terpene	1	14,150

gnlProkkaDCGKMBIL_35 (original name was: gnl|Prokka|DCGKMBIL_35)

Region	Type	From	To	Most similar known cluster		Similarity
Region 31.1	terpene	52,051	72,854

gnlProkkaDCGKMBIL_36 (original name was: gnl|Prokka|DCGKMBIL_36)

Region	Type	From	To	Most similar known cluster		Similarity
Region 32.1	NRPS	115,459	180,847	surfactin	NRP:Lipopeptide	82%

gnlProkkaDCGKMBIL_37 (original name was: gnl|Prokka|DCGKMBIL_37)

Region	Type	From	To	Most similar known cluster		Similarity
Region 33.1	NRPS,betalactone	35,098	97,485	fengycin	NRP	100%

Compact view

gnlProkkaDCGKMBIL_1 - Region 1 - NRPS,PKS-like,T3PKS,transAT-PKS

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Location: 13,892 - 128,664 nt. (total: 114,773 nt) Show pHMM detection rules used

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
NRPS: cds(Condensation and (AMP-binding or A-OX))
T3PKS: cds(Condensation and (AMP-binding or A-OX))
PKS-like: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 13891 - 128664:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gly - ccmal - ohmal - mal) + (ccmal - mal - ohmal - mal) + (Me-ccmal - ohmal - mal) + (Ala - ccmal - ccmal - Me-ccmal) + (mal - mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg1_41

Search NORINE for peptide: strict or relaxed

AMP-binding (497..905): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVSNMAIIYK
Nearest Stachelhaus code(s):: Ala DVSNMAIIYK (91% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg1_44

Search NORINE for peptide: strict or relaxed

CAL_domain (60..471): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 16.2
NH2: 10.3
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1159..1554): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: gly (Gly)

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code(s):: Gly DILQLGMIWK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg1_50

PKS_AT (4..288): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 95.0
inactive: 41.2
Methoxymalonyl-CoA: 29.1
Methylmalonyl-CoA: 22.1
Propionyl-CoA: 16.3
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg1_51

PKS_AT (7..293): pk

ATSignature: (unknown)

No matches above 50%

minowa: inactive

Prediction, score:

inactive: 30.0
Malonyl-CoA: 23.0
Benzoyl-CoA: 8.8
Isobutyryl-CoA: 8.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg1_54

PKS_AT (4..284): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 96.7
Methoxymalonyl-CoA: 50.0
inactive: 35.3
Methylmalonyl-CoA: 31.5
Propionyl-CoA: 22.2
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

gnlProkkaDCGKMBIL_2 - Region 1 - NRP-metallophore,NRPS

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Location: 5,152 - 56,929 nt. (total: 51,778 nt) Show pHMM detection rules used

Region on contig edge.

NRP-metallophore: (VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))
NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 5151 - 56929:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gly - Thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg2_27

Search NORINE for peptide: strict or relaxed

AMP-binding (463..861): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: gly (Gly)

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code(s):: Gly DILQLGLIWK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1519..1935): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code(s):: Thr DFWNIGMVHK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg2_29

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): diOH-Bz

nrpys: diOH-Bz

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Small clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Single AA prediction:: dhb (diOH-Bz)

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code(s):: diOH-Bz PLPAQGVVNK (100% 8Å match); diOH-Bz or Sal PLPAQGVVNK (94% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaDCGKMBIL_2 - Region 2 - CDPS

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Location: 336,004 - 356,750 nt. (total: 20,747 nt) Show pHMM detection rules used

CDPS: (CDPS or cycdipepsynth)

Legend:

core biosynthetic genes

additional biosynthetic genes

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

NRPS/PKS substrates

NRPS/PKS substrate predictions

gnlProkkaDCGKMBIL_3 - Region 1 - T3PKS

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Location: 122,953 - 158,379 nt. (total: 35,427 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

gnlProkkaDCGKMBIL_4 - Region 1 - lanthipeptide-class-ii

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Location: 1 - 21,341 nt. (total: 21,341 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptide(s) for ctg4_9

ctg4_5

Leader:

MELRMSNIG

Core:

YSYIIYGDTRDNCMEDKIMNVKLKVANNDK

Core with dehydrations:

YDhaYIIYGDDhbRDNCysMEDKIMNVKLKVANNDK

antiSMASH-DB 4.0 matches for ctg4_5

100.0% NZ_JABRUZ010000012.1: Lanthipeptides: allorf_004193_004312_lanthipeptide

1

YSYIIYGDTRDNCMEDKIMNVKLKVANNDK

30

YSYIIYGDTRDNCMEDKIMNVKLKVANNDK

1

YSYIIYGDTRDNCMEDKIMNVKLKVANNDK

30

73.3% NZ_CM000728.1and 3 others:

NZ_JH792121.1 Lanthipeptides: allorf_121240_121347_lanthipeptideNZ_JH792158.1 Lanthipeptides: allorf_234781_234888_lanthipeptideNZ_NVFD01000061.1 Lanthipeptides: allorf_11030_11137_lanthipeptide

Lanthipeptides: allorf_5599055_5599162_lanthipeptide

8

DTRDNCMEDKIMNVKLKVANNDK

30

DTRDNCMED+IMNVKLKVANNDK

1

DTRDNCMEDEIMNVKLKVANNDK

23

70.0% NZ_NUQX01000026.1: Lanthipeptides: allorf_172512_172619_lanthipeptide

8

DTRDNCMEDKIMNVKLKVANNDK

30

DTRDNCMED+IMNVKLKV NNDK

1

DTRDNCMEDEIMNVKLKVTNNDK

23

ctg4_10

Leader:

MQWKNQMENLNAYNPVGSVLSELTDTEMDTVAGG

Core:

AQALGFTDGNCLASITADCTPWIWGC

Core with dehydrations:

AQALGFDhbDGNCysLADhaIDhbADCysDhbPWIWGCys

MIBiG 3.1 matches for ctg4_10

26.7% BGC0002110 (QKV49893.1): Lanthipeptide: birimositide

1

AQALGFTDGNCLASITADCTP

21

+ ALG G C ++T +C P

9

SNALGNNGGWC--TLTKECQP

27

15.4% BGC0001155 (AGY49587.1): Thiopeptide: GE2270

10

NCLASITADCTP

21

NC+ C+P

3

NCVCGFCCSCSP

14

antiSMASH-DB 4.0 matches for ctg4_10

100.0% NZ_JABRUZ010000012.1: Lanthipeptides: HRF55_RS15035_lanthipeptide

1

AQALGFTDGNCLASITADCTPWIWGC

26

AQALGFTDGNCLASITADCTPWIWGC

1

AQALGFTDGNCLASITADCTPWIWGC

26

96.2% NZ_CP011686.1and 7 others:

NZ_CP011686.1 Lanthipeptides: ABH13_RS05745_lanthipeptideNZ_JALAKW010000008.1 Lanthipeptides: MOB93_RS17005_lanthipeptideNZ_JALAKW010000008.1 Lanthipeptides: MOB93_RS17000_lanthipeptideNZ_JALAME010000008.1 Lanthipeptides: MOC02_RS17820_lanthipeptideNZ_JALAME010000008.1 Lanthipeptides: MOC02_RS17815_lanthipeptideNZ_JALATF010000002.1 Lanthipeptides: MOD44_RS02115_lanthipeptideNZ_JALAYD010000020.1 Lanthipeptides: MOF39_RS20940_lanthipeptide

Lanthipeptides: ABH13_RS05750_lanthipeptide

1

AQALGFTDGNCLASITADCTPWIWGC

26

AQALGFTDGNCLA+ITADCTPWIWGC

1

AQALGFTDGNCLATITADCTPWIWGC

26

88.5% NZ_JH600294.1and 1 other:

NZ_JH600294.1 Lanthipeptides: GYU_RS0115740_lanthipeptide

Lanthipeptides: GYU_RS0115745_lanthipeptide

1

AQALGFTDGNCLASITADCTPWIWGC

26

AQALGFTDGNCL +ITADCTPW+WGC

1

AQALGFTDGNCLTTITADCTPWLWGC

26

with 14 more sequence matches

85.2% NZ_NVFD01000061.1: Lanthipeptides: COL35_RS24665_lanthipeptide

1

AQALGFTDGNCLASITADCTPWIWGC

26

AQALGFTDGNCLA+ITADCTPWI C

1

AQALGFTDGNCLATITADCTPWIGIC

26

81.5% NZ_CM000728.1and 4 others:

NZ_JH792121.1 Lanthipeptides: IGO_RS31525_lanthipeptideNZ_JH792158.1 Lanthipeptides: IK3_RS31375_lanthipeptideNZ_NUQX01000026.1 Lanthipeptides: COE81_RS20175_lanthipeptideNZ_NVFD01000061.1 Lanthipeptides: COL35_RS30950_lanthipeptide

Lanthipeptides: BCERE0017_RS32175_lanthipeptide

1

AQALGFTDGNCLASITADCTPWIWGC

26

AQALGFTDGNCLA+ITAD TPWI C

1

AQALGFTDGNCLATITADYTPWIGIC

26

77.8% NZ_CM000728.1and 2 others:

NZ_JH792121.1 Lanthipeptides: IGO_RS26860_lanthipeptideNZ_NUQX01000026.1 Lanthipeptides: COE81_RS20170_lanthipeptide

Lanthipeptides: BCERE0017_RS28125_lanthipeptide

1

AQALGFTDGNCLASITADCTPWIWGC

26

AQALGFTDGNCLA+ITADCT W+ C

1

AQALGFTDGNCLATITADCTDWLPIC

26

76.9% NZ_BMLN01000009.1: Lanthipeptides: IEX28_RS15335_lanthipeptide

1

AQALGFTDGNCLASITADCTPWIWGC

26

A A GFTDGNCL SITADCTPW+ C

1

ATAQGFTDGNCLKSITADCTPWLGLC

26

75.9% NZ_CM000728.1and 3 others:

NZ_JH792121.1 Lanthipeptides: allorf_129150_129275_lanthipeptideNZ_NUQX01000026.1 Lanthipeptides: COE81_RS20180_lanthipeptideNZ_NVFD01000061.1 Lanthipeptides: COL35_RS24660_lanthipeptide

Lanthipeptides: BCERE0017_RS28130_lanthipeptide

1

AQALGFTDGNCLASITADCTPWIWGC

26

QALGFTDGNCL SITADCTPW+ GC

1

VQALGFTDGNCLYSITADCTPWLLGC

26

74.1% NZ_CP058552.1: Lanthipeptides: HW560_RS06640_lanthipeptide

1

AQALGFTDGNCLASITADCTP-WIWGC

26

AQA GFTDGNC+++ITADCTP W W C

1

AQAQGFTDGNCVSTITADCTPGWTWVC

27

48.3% NZ_CP011420.1: Lanthipeptides: VK72_RS10865_lanthipeptide

3

ALGFTDGNCLASITADCTP--WIWGC

26

A GFTDG+C+ +ITA C +I GC

3

AYGFTDGDCIRTITAGCDTVCYIKGC

28

30.8% NZ_CP093846.1and 2 others:

NZ_QOIM01000024.1 Lanthipeptides: DQ392_RS34305_lanthipeptideNZ_QOIN01000048.1 Lanthipeptides: DTL70_RS33655_lanthipeptide

Lanthipeptides: MMF93_RS21475_lanthipeptide

8

DGNCLASITADCTPWIWGC

26

+G C S T+ CT + GC

2

NGGCATSRTSLCTDTLSGC

20

30.8% NZ_PYGA01000041.1and 1 other:

NZ_PYGA01000041.1 Lanthipeptides: CLV63_RS33905_lanthipeptide

Lanthipeptides: CLV63_RS33905_lanthipeptide

8

DGNCLASITADCTPWIWGC

26

+G C S T+ CT + GC

4

NGGCETSRTSLCTDTLSGC

22

25.0% NZ_CP051884.1and 2 others:

NZ_CP051884.1 Lanthipeptides: allorf_3265908_3266039_lanthipeptideNZ_CP051884.1 Lanthipeptides: allorf_3265908_3266039_lanthipeptide

Lanthipeptides: allorf_3265908_3266039_lanthipeptide

8

DGNCLASITADCTPW

22

DG A+ T D PW

7

DGVTRAAQTGDPRPW

21

22.4% NZ_KZ859514.1: Lanthipeptides: DPQ64_RS18690_lanthipeptide

4

LGFTDGNCLASITADCTPW

22

LG TD CL S T DC P+

29

LGCTD-TCLCSTTVDCDPY

46

19.2% NZ_BMRY01000010.1and 81 others:

NZ_BMRY01000010.1 Lanthipeptides: IE140_RS27680_lanthipeptideNZ_BMRY01000010.1 Lanthipeptides: IE140_RS27680_lanthipeptideNZ_BMRY01000010.1 Lanthipeptides: IE140_RS27680_lanthipeptideNZ_BMSZ01000004.1 Lanthipeptides: IE135_RS08610_lanthipeptideNZ_BMSZ01000004.1 Lanthipeptides: IE135_RS08610_lanthipeptideNZ_BMSZ01000004.1 Lanthipeptides: IE135_RS08610_lanthipeptideNZ_BMSZ01000004.1 Lanthipeptides: IE135_RS08610_lanthipeptideNZ_BNBJ01000007.1 Lanthipeptides: IE304_RS13825_lanthipeptideNZ_BNBJ01000007.1 Lanthipeptides: IE304_RS13825_lanthipeptideNZ_BNBJ01000007.1 Lanthipeptides: IE304_RS13825_lanthipeptideNZ_BNBJ01000007.1 Lanthipeptides: IE304_RS13825_lanthipeptideNZ_CP010833.1 Lanthipeptides: TK78_RS36080_lanthipeptideNZ_CP010833.1 Lanthipeptides: TK78_RS36080_lanthipeptideNZ_CP010833.1 Lanthipeptides: TK78_RS36080_lanthipeptideNZ_CP010833.1 Lanthipeptides: TK78_RS36080_lanthipeptideNZ_CP013738.1 Lanthipeptides: WQO_RS36380_lanthipeptideNZ_CP013738.1 Lanthipeptides: WQO_RS36380_lanthipeptideNZ_CP013738.1 Lanthipeptides: WQO_RS36380_lanthipeptideNZ_CP013738.1 Lanthipeptides: WQO_RS36380_lanthipeptideNZ_CP021707.1 Lanthipeptides: CCZ36_RS34740_lanthipeptideNZ_CP021707.1 Lanthipeptides: CCZ36_RS34740_lanthipeptideNZ_CP021707.1 Lanthipeptides: CCZ36_RS34740_lanthipeptideNZ_CP021707.1 Lanthipeptides: CCZ36_RS34740_lanthipeptideNZ_CP029361.1 Lanthipeptides: DIJ69_RS34965_lanthipeptideNZ_CP029361.1 Lanthipeptides: DIJ69_RS34965_lanthipeptideNZ_CP029361.1 Lanthipeptides: DIJ69_RS34965_lanthipeptideNZ_CP029361.1 Lanthipeptides: DIJ69_RS34965_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS11695_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS11695_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS11695_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS11695_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS06820_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS06820_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS06820_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS06820_lanthipeptideNZ_CP090837.1 Lanthipeptides: LZ559_RS11615_lanthipeptideNZ_CP090837.1 Lanthipeptides: LZ559_RS11615_lanthipeptideNZ_CP090837.1 Lanthipeptides: LZ559_RS11615_lanthipeptideNZ_CP090837.1 Lanthipeptides: LZ559_RS11615_lanthipeptideNZ_CP117709.1 Lanthipeptides: PSQ21_RS10520_lanthipeptideNZ_DS999644.1 Lanthipeptides: SSGG_RS37575_lanthipeptideNZ_JAJUKK010000002.1 Lanthipeptides: LXH09_RS05290_lanthipeptideNZ_JAJUKK010000002.1 Lanthipeptides: LXH09_RS05290_lanthipeptideNZ_JAJUKK010000002.1 Lanthipeptides: LXH09_RS05290_lanthipeptideNZ_JAJUKK010000002.1 Lanthipeptides: LXH09_RS05290_lanthipeptideNZ_JALDPQ010000065.1 Lanthipeptides: MQC87_RS27525_lanthipeptideNZ_JALDPQ010000065.1 Lanthipeptides: MQC87_RS27525_lanthipeptideNZ_JALDPQ010000065.1 Lanthipeptides: MQC87_RS27525_lanthipeptideNZ_JALDPQ010000065.1 Lanthipeptides: MQC87_RS27525_lanthipeptideNZ_JAMFLF010000007.1 Lanthipeptides: M1212_RS18745_lanthipeptideNZ_JAMFLF010000007.1 Lanthipeptides: M1212_RS18745_lanthipeptideNZ_JAMFLF010000007.1 Lanthipeptides: M1212_RS18745_lanthipeptideNZ_JAMFLF010000007.1 Lanthipeptides: M1212_RS18745_lanthipeptideNZ_JNLT01000008.1 Lanthipeptides: CD02_RS38865_lanthipeptideNZ_JNLT01000008.1 Lanthipeptides: CD02_RS38865_lanthipeptideNZ_JNLT01000008.1 Lanthipeptides: CD02_RS38865_lanthipeptideNZ_JNLT01000008.1 Lanthipeptides: CD02_RS38865_lanthipeptideNZ_KL573557.1 Lanthipeptides: BG84_RS1000000140065_lanthipeptideNZ_KZ679082.1 Lanthipeptides: allorf_2505302_2505508_lanthipeptideNZ_KZ679082.1 Lanthipeptides: allorf_2505302_2505508_lanthipeptideNZ_KZ679082.1 Lanthipeptides: allorf_2505302_2505508_lanthipeptideNZ_KZ819154.1 Lanthipeptides: allorf_5241449_5241619_lanthipeptideNZ_KZ819154.1 Lanthipeptides: allorf_5241449_5241619_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS35630_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS35630_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS35630_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS35630_lanthipeptideNZ_LACR01000026.1 Lanthipeptides: YW5_RS36735_lanthipeptideNZ_LACR01000026.1 Lanthipeptides: YW5_RS36735_lanthipeptideNZ_LACR01000026.1 Lanthipeptides: YW5_RS36735_lanthipeptideNZ_LACR01000026.1 Lanthipeptides: YW5_RS36735_lanthipeptideNZ_LIXK01000002.1 Lanthipeptides: AMK23_RS37800_lanthipeptideNZ_LIXK01000002.1 Lanthipeptides: AMK23_RS37800_lanthipeptideNZ_LIXK01000002.1 Lanthipeptides: AMK23_RS37800_lanthipeptideNZ_LIXK01000002.1 Lanthipeptides: AMK23_RS37800_lanthipeptideNZ_NNBN01000010.1 Lanthipeptides: CG717_RS33255_lanthipeptideNZ_NNBN01000010.1 Lanthipeptides: CG717_RS33255_lanthipeptideNZ_WWGD01000003.1 Lanthipeptides: GTY72_RS37120_lanthipeptideNZ_WWGD01000003.1 Lanthipeptides: GTY72_RS37120_lanthipeptideNZ_WWGD01000003.1 Lanthipeptides: GTY72_RS37120_lanthipeptideNZ_WWGD01000003.1 Lanthipeptides: GTY72_RS37120_lanthipeptide

Lanthipeptides: IE140_RS27680_lanthipeptide

7

TDGNCLASITA

17

TDGNC++ ++

3

TDGNCISVLSV

13

16.7% NZ_CP084033.1: Lanthipeptides: LAZ93_RS17080_lanthipeptide

1

AQALGFTDGNCLASI

15

+ G T GNC+++I

18

TEHCGKTQGNCISNI

32

16.2% NZ_CP020567.1: Thiopeptides: B6264_RS31925_thiopeptide

6

FTDGNCLASIT

16

TDGN L+S++

2

LTDGNALSSVS

12

allorf_001112_001255

Leader:

MAILKLFMFQSFYG

Core:

GGFLSKAVYIGSTPIFHCWKIPIDFIRFYFHHE

Core with dehydrations:

GGFLDhaKAVYIGDhaDhbPIFHCysWKIPIDFIRFYFHHE

antiSMASH-DB 4.0 matches for allorf_001112_001255

100.0% NZ_JABRUZ010000012.1and 1 other:

NZ_JALATF010000002.1 Lanthipeptides: allorf_0054352_0054495_lanthipeptide

Lanthipeptides: allorf_001112_001255_lanthipeptide

1

GGFLSKAVYIGSTPIFHCWKIPIDFIRFYFHHE

33

GGFLSKAVYIGSTPIFHCWKIPIDFIRFYFHHE

1

GGFLSKAVYIGSTPIFHCWKIPIDFIRFYFHHE

33

97.0% NZ_JH600294.1: Lanthipeptides: allorf_063658_063801_lanthipeptide

1

GGFLSKAVYIGSTPIFHCWKIPIDFIRFYFHHE

33

GGFLSKAVYIGSTPI HCWKIPIDFIRFYFHHE

1

GGFLSKAVYIGSTPILHCWKIPIDFIRFYFHHE

33

21.2% NZ_CP091196.1: Lassopeptides: L1857_RS05200_lassopeptide

11

GSTPIFHCWKIPI

23

GS+P W IPI

5

GSSPDNLTWAIPI

17

with 2 more sequence matches

21.2% NZ_JACSJU010000005.1: Lanthipeptides: allorf_80183_80317_lanthipeptide

4

LSKAVYIGSTPIFHCW

19

LS ++YI PI C+

4

LSLSIYINRFPILICF

19

18.2% NZ_BBXD01000030.1: Lanthipeptides: allorf_42087_42218_lanthipeptide

7

AVYIGSTPIFHCWKIPID

24

AV ++H W + ID

8

AVSSNCCDVYHAWVVSID

25

allorf_012396_012518

Leader:

MDCYYIKSQVLGM

Core:

DGSTLAYLFATKPCLQNNVKMIMLPLK

Core with dehydrations:

DGDhaDhbLAYLFADhbKPCysLQNNVKMIMLPLK

antiSMASH-DB 4.0 matches for allorf_012396_012518

100.0% NZ_JABRUZ010000012.1: Lanthipeptides: allorf_012396_012518_lanthipeptide

1

DGSTLAYLFATKPCLQNNVKMIMLPLK

27

DGSTLAYLFATKPCLQNNVKMIMLPLK

1

DGSTLAYLFATKPCLQNNVKMIMLPLK

27

17.9% NZ_KB896392.1: Lanthipeptides: allorf_139206_139337_lanthipeptide

10

ATKPCLQNNVKMIML

24

A PC ++ + +IM+

2

ARPPCCRHTITVIMM

16

allorf_012427_012570

Leader:

MGGEVVSEFGG

Core:

AAGGILNGLLLYQVTGSRNGWEYSGLSICNKTLFAK

Core with dehydrations:

AAGGILNGLLLYQVDhbGDhaRNGWEYDhaGLDhaICysNKDhbLFAK

MIBiG 3.1 matches for allorf_012427_012570

13.9% BGC0000553 (SSGG_RS09925): Lanthipeptide: SRO15-2212

22

EYSGLSI

28

EYS LS+

11

EYSSLSV

17

antiSMASH-DB 4.0 matches for allorf_012427_012570

100.0% NZ_JABRUZ010000012.1: Lanthipeptides: allorf_012427_012570_lanthipeptide

1

AAGGILNGLLLYQVTGSRNGWEYSGLSICNKTLFAK

36

AAGGILNGLLLYQVTGSRNGWEYSGLSICNKTLFAK

1

AAGGILNGLLLYQVTGSRNGWEYSGLSICNKTLFAK

36

9.8% NZ_MCIF01000002.1: Lanthipeptides: allorf_2113382_2113621_lanthipeptide

5

ILNGLLLYQVTGSR

18

+ NGLL + ++G R

47

LFNGLLPFSLSGER

60

allorf_014349_014459

Leader:

MRSASFAA

Core:

DILCDIYRSFPSSYIVKLLKNFLFFFRI

Core with dehydrations:

DILCysDIYRDhaFPDhaDhaYIVKLLKNFLFFFRI

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg4_5 - Class II

Cleavage pHMM score: -3.70

RODEO score: 0

Monoisotopic mass: 3516.7 Da

Molecular weight: 3519.0 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 3537.0 Da N = 1

ctg4_10 - Class II

Cleavage pHMM score: 4.60

RODEO score: 0

Monoisotopic mass: 2641.2 Da

Molecular weight: 2643.0 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2661.0 Da N = 1

allorf_001112_001255 - Class II

Cleavage pHMM score: -5.70

RODEO score: 0

Monoisotopic mass: 3871.0 Da

Molecular weight: 3873.5 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 3891.5 Da N = 1; 3909.5 Da N = 2

allorf_012396_012518 - Class II

Cleavage pHMM score: -1.80

RODEO score: 0

Monoisotopic mass: 2954.6 Da

Molecular weight: 2956.6 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2974.6 Da N = 1; 2992.6 Da N = 2

allorf_012427_012570 - Class II

Cleavage pHMM score: -2.60

RODEO score: 0

Monoisotopic mass: 3724.0 Da

Molecular weight: 3726.2 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 3744.3 Da N = 1; 3762.3 Da N = 2; 3780.3 Da N = 3; 3798.3 Da N = 4

allorf_014349_014459 - Class II

Cleavage pHMM score: -5.60

RODEO score: 0

Monoisotopic mass: 3402.9 Da

Molecular weight: 3405.0 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 3423.1 Da N = 1; 3441.1 Da N = 2

gnlProkkaDCGKMBIL_23 - Region 1 - other

Download region GenBank file

Download region SVG

Location: 190,700 - 232,118 nt. (total: 41,419 nt) Show pHMM detection rules used

other: (LmbU or Neocarzinostat or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaDCGKMBIL_23 - Region 2 - sactipeptide

Download region GenBank file

Download region SVG

Location: 234,859 - 256,470 nt. (total: 21,612 nt) Show pHMM detection rules used

sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Sactipeptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

Sactipeptide predictions

Sactipeptide(s) for ctg22_242

ctg22_242

Leader:

MKKAVIVENK

Core:

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

antiSMASH-DB 4.0 matches for ctg22_242

100.0% NC_000964.3and 235 others:

NC_014479.1 Sactipeptides: BSUW23_RS18740_sactipeptideNC_014639.1 Sactipeptides: BATR1942_RS15950_sactipeptideNC_014976.1 Sactipeptides: BSN5_RS09700_sactipeptideNC_016047.1 Sactipeptides: GYO_RS41165_sactipeptideNC_017195.1 Sactipeptides: I33_RS18040_sactipeptideNC_017743.1 Sactipeptides: MY9_RS18920_sactipeptideNC_019896.1 Sactipeptides: A7A1_RS01935_sactipeptideNC_020244.1 Sactipeptides: C663_RS18295_sactipeptideNZ_BDDH01000003.1 Sactipeptides: A7P71_RS10610_sactipeptideNZ_CABIVP010000002.1 Sactipeptides: FY199_RS09010_sactipeptideNZ_CP007409.1 Sactipeptides: Q433_RS18950_sactipeptideNZ_CP009796.1 Sactipeptides: OB04_RS19085_sactipeptideNZ_CP011101.1 Sactipeptides: bslm_RS18365_sactipeptideNZ_CP011534.1 Sactipeptides: ABA10_RS18725_sactipeptideNZ_CP011802.1 Sactipeptides: D068_RS17505_sactipeptideNZ_CP016767.1 Sactipeptides: BCV50_RS14935_sactipeptideNZ_CP017072.1 Sactipeptides: BGM23_RS02945_sactipeptideNZ_CP017112.1 Sactipeptides: BS16045_RS19810_sactipeptideNZ_CP017313.1 Sactipeptides: BH660_RS14630_sactipeptideNZ_CP017314.1 Sactipeptides: BSBS38_RS19215_sactipeptideNZ_CP017676.1 Sactipeptides: BKN48_RS08085_sactipeptideNZ_CP018173.1 Sactipeptides: BAX60_RS03615_sactipeptideNZ_CP020367.1 Sactipeptides: BSK2_RS19060_sactipeptideNZ_CP020722.1 Sactipeptides: B7470_RS09560_sactipeptideNZ_CP020915.1 Sactipeptides: B9L64_RS11255_sactipeptideNZ_CP021169.1 Sactipeptides: B9N48_RS18685_sactipeptideNZ_CP021498.1 Sactipeptides: S101444_RS19170_sactipeptideNZ_CP021892.1 Sactipeptides: S100333_RS19720_sactipeptideNZ_CP021903.1 Sactipeptides: CD007_RS18975_sactipeptideNZ_CP021911.1 Sactipeptides: CDO84_RS18225_sactipeptideNZ_CP021921.1 Sactipeptides: S101392_RS19440_sactipeptideNZ_CP022391.1 Sactipeptides: CFK25_RS18875_sactipeptideNZ_CP022890.1 Sactipeptides: CJZ70_RS01210_sactipeptideNZ_CP023257.1 Sactipeptides: CLD04_RS19470_sactipeptideNZ_CP023409.1 Sactipeptides: Bateq7PJ16_RS20450_sactipeptideNZ_CP025941.1 Sactipeptides: C0W65_RS07300_sactipeptideNZ_CP026010.1 Sactipeptides: BS11774_RS03710_sactipeptideNZ_CP026030.1 Sactipeptides: C2H91_RS12110_sactipeptideNZ_CP026035.1 Sactipeptides: C2H96_RS13375_sactipeptideNZ_CP026036.1 Sactipeptides: C2H93_RS16885_sactipeptideNZ_CP026521.1 Sactipeptides: C1T29_RS22385_sactipeptideNZ_CP028201.1 Sactipeptides: C7M16_RS17535_sactipeptideNZ_CP028202.1 Sactipeptides: C7M17_RS17600_sactipeptideNZ_CP028217.1 Sactipeptides: C7M29_RS06900_sactipeptideNZ_CP028218.1 Sactipeptides: C7M30_RS12605_sactipeptideNZ_CP028812.1 Sactipeptides: DAE22_RS20770_sactipeptideNZ_CP029364.1 Sactipeptides: DIC78_RS12275_sactipeptideNZ_CP029461.1 Sactipeptides: DJ572_RS18795_sactipeptideNZ_CP029465.1 Sactipeptides: DKG76_RS19825_sactipeptideNZ_CP029609.1 Sactipeptides: DL538_RS20030_sactipeptideNZ_CP031675.1 Sactipeptides: DYS67_RS19275_sactipeptideNZ_CP031783.1 Sactipeptides: D0808_RS00710_sactipeptideNZ_CP031784.1 Sactipeptides: D0819_RS14700_sactipeptideNZ_CP032853.1 Sactipeptides: D9C10_RS17955_sactipeptideNZ_CP032855.1 Sactipeptides: D9C11_RS09165_sactipeptideNZ_CP035161.1 Sactipeptides: EQH88_RS19675_sactipeptideNZ_CP035167.1 Sactipeptides: EQJ08_RS19095_sactipeptideNZ_CP035226.1 Sactipeptides: EQW70_RS20085_sactipeptideNZ_CP035231.1 Sactipeptides: EQZ01_RS19685_sactipeptideNZ_CP035391.1 Sactipeptides: ES965_RS19370_sactipeptideNZ_CP035395.1 Sactipeptides: ES968_RS19740_sactipeptideNZ_CP035401.1 Sactipeptides: ETA19_RS19595_sactipeptideNZ_CP035402.1 Sactipeptides: ES969_RS19660_sactipeptideNZ_CP035403.1 Sactipeptides: ETA15_RS19805_sactipeptideNZ_CP035406.1 Sactipeptides: ETK61_RS20735_sactipeptideNZ_CP035413.1 Sactipeptides: ETL58_RS19505_sactipeptideNZ_CP039935.1 Sactipeptides: FCJ76_RS19255_sactipeptideNZ_CP045006.1 Sactipeptides: F9B13_RS01950_sactipeptideNZ_CP045425.1 Sactipeptides: GCU76_RS20710_sactipeptideNZ_CP045816.1 Sactipeptides: GII86_RS19920_sactipeptideNZ_CP045824.1 Sactipeptides: GII78_RS20125_sactipeptideNZ_CP046591.1 Sactipeptides: GO004_RS15965_sactipeptideNZ_CP046860.1 Sactipeptides: GPJ55_RS11605_sactipeptideNZ_CP047645.1 Sactipeptides: GSN02_RS19265_sactipeptideNZ_CP049924.1 Sactipeptides: G4G26_RS18960_sactipeptideNZ_CP050705.1 Sactipeptides: HCU65_RS18920_sactipeptideNZ_CP051462.1 Sactipeptides: HC662_RS19240_sactipeptideNZ_CP051464.1 Sactipeptides: HC660_RS18970_sactipeptideNZ_CP054050.1 Sactipeptides: HNV25_RS02005_sactipeptideNZ_CP054177.1 Sactipeptides: HR084_RS18935_sactipeptideNZ_CP054584.1 Sactipeptides: HT135_RS19775_sactipeptideNZ_CP060193.1 Sactipeptides: H7F27_RS02180_sactipeptideNZ_CP060417.1 Sactipeptides: H8S71_RS18495_sactipeptideNZ_CP061284.1 Sactipeptides: ICJ61_RS19715_sactipeptideNZ_CP061870.1 Sactipeptides: IE382_RS22305_sactipeptideNZ_CP062497.1 Sactipeptides: IHV08_RS19770_sactipeptideNZ_CP063276.1 Sactipeptides: IM743_RS18070_sactipeptideNZ_CP065858.1 Sactipeptides: I7X10_RS03370_sactipeptideNZ_CP069789.1 Sactipeptides: JR441_RS19085_sactipeptideNZ_CP070483.1 Sactipeptides: JQX68_RS19175_sactipeptideNZ_CP070976.1 Sactipeptides: JYG31_RS19675_sactipeptideNZ_CP071043.1 Sactipeptides: JS609_RS19245_sactipeptideNZ_CP073265.1 Sactipeptides: KCX77_RS18900_sactipeptideNZ_CP075344.1 Sactipeptides: KIL00_RS20100_sactipeptideNZ_CP076083.1 Sactipeptides: KFF76_RS18635_sactipeptideNZ_CP079759.1 Sactipeptides: KXZ66_RS19695_sactipeptideNZ_CP080508.1 Sactipeptides: K0V03_RS08595_sactipeptideNZ_CP089148.1 Sactipeptides: LRO88_RS20980_sactipeptideNZ_CP090125.1 Sactipeptides: LXE94_RS19505_sactipeptideNZ_CP093289.1 Sactipeptides: MNG38_RS19730_sactipeptideNZ_CP093546.1 Sactipeptides: MOW04_RS19180_sactipeptideNZ_CP095736.1 Sactipeptides: MX663_RS20090_sactipeptideNZ_CP096590.1 Sactipeptides: M0696_RS18995_sactipeptideNZ_CP096889.1 Sactipeptides: EFK13_RS19225_sactipeptideNZ_CP098738.1 Sactipeptides: NDR85_RS18965_sactipeptideNZ_CP100651.1 Sactipeptides: NLW79_RS19990_sactipeptideNZ_CP100752.1 Sactipeptides: NLV76_RS19060_sactipeptideNZ_CP101718.1 Sactipeptides: NPA28_RS19075_sactipeptideNZ_CP101936.1 Sactipeptides: NP434_RS18980_sactipeptideNZ_CP103352.1 Sactipeptides: NX823_RS19780_sactipeptideNZ_CP104878.1 Sactipeptides: N8A75_RS20105_sactipeptideNZ_CP107539.1 Sactipeptides: OEG95_RS19105_sactipeptideNZ_CP110264.1 Sactipeptides: OMK57_RS18975_sactipeptideNZ_CP114899.1 Sactipeptides: O6U12_RS19480_sactipeptideNZ_CP116773.1 Sactipeptides: PNF29_RS01990_sactipeptideNZ_FTMW01000001.1 Sactipeptides: BW968_RS02045_sactipeptideNZ_JAAUXF010000005.1 Sactipeptides: HC742_RS19325_sactipeptideNZ_JABRUZ010000003.1 Sactipeptides: HRF55_RS03085_sactipeptideNZ_JABRVH010000018.1 Sactipeptides: HRF53_RS09100_sactipeptideNZ_JABUKD010000002.1 Sactipeptides: HRW04_RS09345_sactipeptideNZ_JAEACL010000001.1 Sactipeptides: I5F14_RS00800_sactipeptideNZ_JAHVOC010000002.1 Sactipeptides: KXD37_RS07830_sactipeptideNZ_JAJFDG010000003.1 Sactipeptides: LJF29_RS11575_sactipeptideNZ_JAJHUI010000011.1 Sactipeptides: LK399_RS16325_sactipeptideNZ_JALAJC010000012.1 Sactipeptides: MOB18_RS16080_sactipeptideNZ_JALAKW010000005.1 Sactipeptides: MOB93_RS12665_sactipeptideNZ_JALAKZ010000001.1 Sactipeptides: MOB76_RS02240_sactipeptideNZ_JALALA010000011.1 Sactipeptides: MOB82_RS15020_sactipeptideNZ_JALALE010000020.1 Sactipeptides: MOB33_RS20855_sactipeptideNZ_JALALO010000006.1 Sactipeptides: MOB75_RS09230_sactipeptideNZ_JALAMD010000002.1 Sactipeptides: MOB22_RS02315_sactipeptideNZ_JALAME010000005.1 Sactipeptides: MOC02_RS13805_sactipeptideNZ_JALAMJ010000012.1 Sactipeptides: MOB80_RS16635_sactipeptideNZ_JALAMO010000007.1 Sactipeptides: MOB98_RS08535_sactipeptideNZ_JALAMR010000019.1 Sactipeptides: MOC09_RS17975_sactipeptideNZ_JALAMZ010000002.1 Sactipeptides: MOC43_RS01370_sactipeptideNZ_JALANN010000012.1 Sactipeptides: MOC49_RS18290_sactipeptideNZ_JALANX010000001.1 Sactipeptides: MOC25_RS03365_sactipeptideNZ_JALAPT010000001.1 Sactipeptides: MOC95_RS01580_sactipeptideNZ_JALAPV010000005.1 Sactipeptides: MOC91_RS13515_sactipeptideNZ_JALAPW010000003.1 Sactipeptides: MOD18_RS06235_sactipeptideNZ_JALAPX010000003.1 Sactipeptides: MOC97_RS06805_sactipeptideNZ_JALAPZ010000002.1 Sactipeptides: MOC81_RS03830_sactipeptideNZ_JALAQA010000008.1 Sactipeptides: MOD07_RS14955_sactipeptideNZ_JALAQC010000001.1 Sactipeptides: MOD00_RS01290_sactipeptideNZ_JALAQD010000002.1 Sactipeptides: MOD08_RS05770_sactipeptideNZ_JALAQE010000002.1 Sactipeptides: MOD19_RS04725_sactipeptideNZ_JALASB010000002.1 Sactipeptides: MOD42_RS03685_sactipeptideNZ_JALASC010000024.1 Sactipeptides: MOD69_RS20580_sactipeptideNZ_JALASM010000006.1 Sactipeptides: MOD51_RS10970_sactipeptideNZ_JALASR010000006.1 Sactipeptides: MOD87_RS10780_sactipeptideNZ_JALAST010000011.1 Sactipeptides: MOE17_RS14670_sactipeptideNZ_JALASW010000005.1 Sactipeptides: MOE15_RS06925_sactipeptideNZ_JALATC010000001.1 Sactipeptides: MOD56_RS03380_sactipeptideNZ_JALATD010000001.1 Sactipeptides: MOE02_RS03350_sactipeptideNZ_JALATE010000006.1 Sactipeptides: MOD98_RS11440_sactipeptideNZ_JALATF010000003.1 Sactipeptides: MOD44_RS09960_sactipeptideNZ_JALATG010000002.1 Sactipeptides: MOE16_RS03490_sactipeptideNZ_JALATJ010000007.1 Sactipeptides: MOD90_RS15770_sactipeptideNZ_JALATU010000001.1 Sactipeptides: MOE27_RS01985_sactipeptideNZ_JALATV010000005.1 Sactipeptides: MOD97_RS07020_sactipeptideNZ_JALAUA010000008.1 Sactipeptides: MOD32_RS16030_sactipeptideNZ_JALAUD010000001.1 Sactipeptides: MOE28_RS03345_sactipeptideNZ_JALAUJ010000006.1 Sactipeptides: MOE37_RS12685_sactipeptideNZ_JALAUK010000012.1 Sactipeptides: MOE38_RS11825_sactipeptideNZ_JALAUV010000003.1 Sactipeptides: MOE71_RS06545_sactipeptideNZ_JALAUW010000015.1 Sactipeptides: MOE83_RS13210_sactipeptideNZ_JALAVA010000002.1 Sactipeptides: MOE81_RS02625_sactipeptideNZ_JALAVE010000001.1 Sactipeptides: MOE67_RS03645_sactipeptideNZ_JALAVI010000011.1 Sactipeptides: MOE80_RS14660_sactipeptideNZ_JALAVK010000006.1 Sactipeptides: MOE96_RS10120_sactipeptideNZ_JALAVL010000002.1 Sactipeptides: MOE60_RS03290_sactipeptideNZ_JALAVM010000009.1 Sactipeptides: MOE49_RS16195_sactipeptideNZ_JALAVO010000008.1 Sactipeptides: MOE63_RS14665_sactipeptideNZ_JALAVQ010000003.1 Sactipeptides: MOE59_RS02420_sactipeptideNZ_JALAVS010000002.1 Sactipeptides: MOE46_RS02250_sactipeptideNZ_JALAVT010000005.1 Sactipeptides: MOF25_RS08325_sactipeptideNZ_JALAVU010000004.1 Sactipeptides: MOE78_RS09660_sactipeptideNZ_JALAVV010000004.1 Sactipeptides: MOE66_RS02855_sactipeptideNZ_JALAVW010000001.1 Sactipeptides: MOE86_RS01005_sactipeptideNZ_JALAVX010000009.1 Sactipeptides: MOE40_RS07525_sactipeptideNZ_JALAVZ010000002.1 Sactipeptides: MOF00_RS02525_sactipeptideNZ_JALAWB010000008.1 Sactipeptides: MOE87_RS15020_sactipeptideNZ_JALAWK010000002.1 Sactipeptides: MOF06_RS12140_sactipeptideNZ_JALAWW010000010.1 Sactipeptides: MOF23_RS17300_sactipeptideNZ_JALAXQ010000012.1 Sactipeptides: MOF24_RS14120_sactipeptideNZ_JALAXV010000001.1 Sactipeptides: MOF15_RS00375_sactipeptideNZ_JALAYA010000016.1 Sactipeptides: MOF34_RS08915_sactipeptideNZ_JALAYD010000019.1 Sactipeptides: MOF39_RS20725_sactipeptideNZ_JALNTO010000006.1 Sactipeptides: MTN95_RS11045_sactipeptideNZ_JAMDFN010000008.1 Sactipeptides: M3M31_RS18245_sactipeptideNZ_JAMYDW010000003.1 Sactipeptides: NHM07_RS10830_sactipeptideNZ_JANBMP010000002.1 Sactipeptides: NL430_RS07940_sactipeptideNZ_JANDGG010000001.1 Sactipeptides: NKU38_RS03365_sactipeptideNZ_JANFAP010000001.1 Sactipeptides: NEC81_RS02065_sactipeptideNZ_JAQFFE010000015.1 Sactipeptides: PG051_RS13540_sactipeptideNZ_JAQOXM010000001.1 Sactipeptides: PO770_RS01950_sactipeptideNZ_JH600279.1 Sactipeptides: GYU_RS0104160_sactipeptideNZ_JXHL01000020.1 Sactipeptides: B4069_RS07025_sactipeptideNZ_JXHP01000031.1 Sactipeptides: B4073_RS09425_sactipeptideNZ_JXHR01000010.1 Sactipeptides: B4146_RS06925_sactipeptideNZ_KZ848487.1 Sactipeptides: DSL71_RS14015_sactipeptideNZ_LPVE01000021.1 Sactipeptides: AU385_RS06600_sactipeptideNZ_LSBB01000001.1 Sactipeptides: AXI57_RS01770_sactipeptideNZ_LUUT01000004.1 Sactipeptides: A6751_RS18460_sactipeptideNZ_MOEO01000004.1 Sactipeptides: BLL41_RS09830_sactipeptideNZ_MUXL01000002.1 Sactipeptides: B0W20_RS08845_sactipeptideNZ_MZZI01000001.1 Sactipeptides: B2G85_RS18515_sactipeptideNZ_NBBO01000003.1 Sactipeptides: B6K89_RS01830_sactipeptideNZ_NERK01000024.1 Sactipeptides: B9T64_RS18540_sactipeptideNZ_NJRD01000003.1 Sactipeptides: CE053_RS09115_sactipeptideNZ_NJRE01000002.1 Sactipeptides: CE047_RS07205_sactipeptideNZ_NKAK01000003.1 Sactipeptides: CE489_RS10400_sactipeptideNZ_NMOM01000004.1 Sactipeptides: CFI07_RS07245_sactipeptideNZ_PHIE01000002.1 Sactipeptides: CVV77_RS10760_sactipeptideNZ_PJCT01000002.1 Sactipeptides: CW370_RS11825_sactipeptideNZ_PVQM01000002.1 Sactipeptides: C6W22_RS11490_sactipeptideNZ_PVQN01000002.1 Sactipeptides: C6W23_RS05885_sactipeptideNZ_PVRK01000001.1 Sactipeptides: C6350_RS02025_sactipeptideNZ_PVWC01000004.1 Sactipeptides: C6372_RS11675_sactipeptideNZ_QRFZ01000012.1 Sactipeptides: DXT72_RS19010_sactipeptideNZ_SDKE01000003.1 Sactipeptides: EUA35_RS12130_sactipeptideNZ_SHOB01000002.1 Sactipeptides: ES060_RS14270_sactipeptideNZ_SIRN01000006.1 Sactipeptides: EYH65_RS15720_sactipeptideNZ_SNWK01000001.1 Sactipeptides: DFO69_RS02055_sactipeptideNZ_SOBO01000012.1 Sactipeptides: DFO78_RS18210_sactipeptideNZ_SORJ01000001.1 Sactipeptides: BJ795_RS03350_sactipeptideNZ_VBRP01000025.1 Sactipeptides: FE220_RS07065_sactipeptideNZ_VFNF01000001.1 Sactipeptides: FB592_RS03405_sactipeptideNZ_VIOH01000001.1 Sactipeptides: FLN47_RS01935_sactipeptideNZ_VLJK01000012.1 Sactipeptides: L605_RS10195_sactipeptideNZ_VLJL01000006.1 Sactipeptides: L604_RS05585_sactipeptideNZ_VLJX01000001.1 Sactipeptides: L609_RS01950_sactipeptideNZ_VTEK01000003.1 Sactipeptides: FZC71_RS10310_sactipeptideNZ_WTKJ01000004.1 Sactipeptides: NWT17_RS06185_sactipeptide

Sactipeptides: BSU_37350_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

97.0% NZ_CP092751.1: Sactipeptides: MKF32_RS18515_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GCATCSIGA CLVDGPIPDFEIAGATGLFGLWG

1

GCATCSIGAVCLVDGPIPDFEIAGATGLFGLWG

33

93.9% NZ_CP048852.1: Sactipeptides: G4P54_RS19300_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GCATCSIGA CLVDGPIPDFE+AGATGLFGLWG

1

GCATCSIGAVCLVDGPIPDFEVAGATGLFGLWG

33

with 15 more sequence matches

90.9% NZ_JALAKO010000018.1and 1 other:

NZ_JALAOG010000035.1 Sactipeptides: MOC96_RS18415_sactipeptide

Sactipeptides: MOB26_RS11095_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GCATCSIGA CLVDGPIPDFEI G TGLFGLWG

1

GCATCSIGAVCLVDGPIPDFEIGGVTGLFGLWG

33

87.9% NZ_CP026362.1and 3 others:

NZ_CP033052.1 Sactipeptides: D9779_RS19215_sactipeptideNZ_JALAPG010000031.1 Sactipeptides: MOC70_RS13155_sactipeptideNZ_JALAQI010000016.1 Sactipeptides: MOD13_RS11485_sactipeptide

Sactipeptides: BV11031_RS20865_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GCATCSIGA CLVDG IPDFEI G TGLFGLWG

1

GCATCSIGAVCLVDGFIPDFEIGGVTGLFGLWG

33

78.8% NZ_NXEM01000021.1: Sactipeptides: CPT06_RS05595_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GC TCSIGA CLV+GPIPDF+ G TGLFGLWG

1

GCTTCSIGAVCLVNGPIPDFKTGGVTGLFGLWG

33

72.7% NC_014925.1and 17 others:

NZ_ANOI01000001.1 Sactipeptides: F779_RS13290_sactipeptideNZ_CP031604.1 Sactipeptides: DNJ55_RS07055_sactipeptideNZ_CP031605.1 Sactipeptides: DRC71_RS00165_sactipeptideNZ_CP035741.1 Sactipeptides: EW136_RS01865_sactipeptideNZ_CP039747.1 Sactipeptides: EFT29_RS00935_sactipeptideNZ_CP054206.2 Sactipeptides: HP560_RS11995_sactipeptideNZ_CP060700.1 Sactipeptides: H9Q12_RS10940_sactipeptideNZ_CP065920.1 Sactipeptides: JC281_RS11580_sactipeptideNZ_CP076465.1 Sactipeptides: KDE16_RS00560_sactipeptideNZ_JANPRJ010000013.1 Sactipeptides: NVR03_RS10250_sactipeptideNZ_JANPRN010000039.1 Sactipeptides: NVR04_RS07875_sactipeptideNZ_JTKO01000012.1 Sactipeptides: NO87_RS10650_sactipeptideNZ_LR134267.1 Sactipeptides: EL085_RS11430_sactipeptideNZ_MQMO01000006.1 Sactipeptides: BSR38_RS07375_sactipeptideNZ_MQNF01000024.1 Sactipeptides: BSR36_RS12515_sactipeptideNZ_QQPJ01000025.1 Sactipeptides: DV949_RS11300_sactipeptideNZ_SEZW01000001.1 Sactipeptides: EWV33_RS08610_sactipeptide

Sactipeptides: SPSINT_RS00615_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGL

31

GC+TCSIGAACL+DGP+PDFE+ G TG+FGL

1

GCSTCSIGAACLIDGPLPDFEVMGITGIFGL

31

69.7% NZ_CP027770.1: Sactipeptides: C7J90_RS04260_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGL

31

GC+ CSIGAACL+DGP PDFE+ G TG FGL

1

GCSACSIGAACLIDGPFPDFEVMGITGTFGL

31

69.7% NZ_CP066885.1: Sactipeptides: JGZ27_RS11325_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGL

31

GC+TCSIG ACL+DGP+PDFE+ G TG+FGL

1

GCSTCSIGVACLIDGPLPDFEVMGITGIFGL

31

69.7% NZ_CP094808.1and 3 others:

NZ_CP094809.1 Sactipeptides: MUA95_RS01320_sactipeptideNZ_CP094813.1 Sactipeptides: MUA84_RS01300_sactipeptideNZ_VKCY01000004.1 Sactipeptides: FNK43_RS05155_sactipeptide

Sactipeptides: MUA11_RS01375_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGL

31

GC+ C+IGAACL DGPIPDFE+AG TG FG+

1

GCSACAIGAACLADGPIPDFEVAGITGTFGI

31

66.7% NZ_ATDF02000020.1and 1 other:

NZ_KV827785.1 Sactipeptides: HMPREF2580_RS10900_sactipeptide

Sactipeptides: M462_RS08950_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGL

31

GC+ C++GAACL DGPIPDFE+AG TG FG+

1

GCSACAVGAACLADGPIPDFEVAGITGTFGM

31

63.6% NC_022584.1and 2 others:

NZ_CP047883.1 Sactipeptides: M594_RS05585_sactipeptideNZ_KV802690.1 Sactipeptides: HMPREF2764_RS03300_sactipeptide

Sactipeptides: N596_RS03165_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GC+ C+IGA CL DGPIPDFEIAG + +F +G

1

GCSVCAIGAVCLADGPIPDFEIAGVSAVFTAFG

33

63.6% NZ_CP063367.1and 1 other:

NZ_LR134263.1 Sactipeptides: EL101_RS12790_sactipeptide

Sactipeptides: IPU22_RS12430_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGL

31

GC+ C++GA CL DGPIPDFE+AG TG FG+

1

GCSACAVGAVCLADGPIPDFEVAGITGTFGI

31

60.6% NZ_LGRV01000006.1: Sactipeptides: AEA09_RS16245_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GC+ CSIGA CL+ GP+PDFE+A +G+F +WG

1

GCSACSIGAICLITGPVPDFEVASISGIFSVWG

33

54.5% NZ_CP066713.1: Sactipeptides: JGZ50_RS11620_sactipeptide

2

CATCSIGAACLVDGPIPDFEIAGATGLF

29

C+TCSIGAACL+DGP+PDF G F

1

CSTCSIGAACLIDGPLPDFRSHGNYWNF

28

42.4% NZ_PIZD01000012.1: Sactipeptides: allorf_25390_25524_sactipeptide

2

CATCSIGAACLVDGPIPDFEIAGATGLFGLW

32

C+ C++GA CL DGP PD E+ G + G +

3

CSFCAVGAGCLADGPFPDAEVVGVALIAGAF

33

18.2% NZ_CP016898.1: Lassopeptides: BEN76_RS17395_lassopeptide

14

DGPIPDFEIAGATGLF

29

GP+P++ + G G F

3

KGPLPEYFLMGGGGNF

18

17.1% NC_017030.1: Lanthipeptides: allorf_07530736_07530897_lanthipeptide

1

GCATCSIGAACLVDGPI

17

G +I C VDGP+

11

GVLRPAIARPCFVDGPV

27

Sactipeptides

Core peptide predictions

ctg22_242: Putative sactipeptide; RODEO score: 33.0; Core sequence, approximate: GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

gnlProkkaDCGKMBIL_26 - Region 1 - terpene

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Location: 1 - 14,150 nt. (total: 14,150 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaDCGKMBIL_35 - Region 1 - terpene

Download region GenBank file

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Location: 52,051 - 72,854 nt. (total: 20,804 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaDCGKMBIL_36 - Region 1 - NRPS

Download region GenBank file

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Location: 115,459 - 180,847 nt. (total: 65,389 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 115458 - 180847:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Glu - Leu - D-Leu) + (Val - Asp - D-Leu) + (Leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg32_150

Search NORINE for peptide: strict or relaxed

AMP-binding (469..867): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGCVFK
Nearest Stachelhaus code(s):: Leu DAFFLGCVFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg32_151

Search NORINE for peptide: strict or relaxed

AMP-binding (470..864): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWIGGTFK
Nearest Stachelhaus code(s):: Val DAFWIGGTFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1501..1904): Asp

nrpys: Asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asp (Asp)

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHIGK
Nearest Stachelhaus code(s):: Asp DLTKVGHIGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (2546..2933): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code(s):: Leu DAWFLGNVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg32_152

Search NORINE for peptide: strict or relaxed

AMP-binding (466..867): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: gln (Gln)

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDLGVVDK
Nearest Stachelhaus code(s):: Glu DAKDLGVVDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1510..1908): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFMMGMVFK
Nearest Stachelhaus code(s):: Leu DAFMMGMVFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (2550..2938): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code(s):: Leu DAWFLGNVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaDCGKMBIL_37 - Region 1 - NRPS,betalactone

Download region GenBank file

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Location: 35,098 - 97,485 nt. (total: 62,388 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

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Similar known gene clusters from MIBiG 3.1

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 35097 - 97485:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Glu - D-Orn) + (Tyr - D-Thr) + (Glu - D-Val) + (Pro - Glu - D-Tyr) + (Ile)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg33_58

AMP-binding (13..445): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: -GLHIAAPVK
Nearest Stachelhaus code(s):: Z-ahmohOrn FGLHIASTCK (56% 8Å match); Ile DGLFIGIPVK (32% 8Å match)
Stachelhaus code match:: 60% (weak)

ctg33_62

Search NORINE for peptide: strict or relaxed

AMP-binding (474..867): Ile

nrpys: Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: ile (Ile)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFYGITFK
Nearest Stachelhaus code(s):: Ile DAFFYGITFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg33_63

Search NORINE for peptide: strict or relaxed

AMP-binding (469..866): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
Small clusters prediction:: pro (Pro)
Single AA prediction:: pro (Pro)

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code(s):: Pro DVQFIAHVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1500..1901): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: glu (Glu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGSVEK
Nearest Stachelhaus code(s):: Glu DAWHFGSVEK (97% 8Å match); Gln DAWHFGSVEK (91% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (2539..2933): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: Polar aromatic ring (Tyr, bOH-Tyr)
Single AA prediction:: tyr (Tyr)

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code(s):: Tyr DGTITAEVAK (97% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg33_64

Search NORINE for peptide: strict or relaxed

AMP-binding (469..870): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: glu (Glu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGVDK
Nearest Stachelhaus code(s):: Glu DAWHFGGVDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1510..1903): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: DVFWIGGTFK
Nearest Stachelhaus code(s):: Val DVFWIGGTFK (100% 8Å match); Ala or Val DVFWIGGTFK (91% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg33_65

Search NORINE for peptide: strict or relaxed

AMP-binding (474..865): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: Polar aromatic ring (Tyr, bOH-Tyr)
Single AA prediction:: tyr (Tyr)

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code(s):: Tyr DGTITAEVAK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1505..1903): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code(s):: Thr DFWNIGMVHK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg33_66

Search NORINE for peptide: strict or relaxed

AMP-binding (463..864): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: glu (Glu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGVDK
Nearest Stachelhaus code(s):: Glu DAWHFGGVDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1503..1908): Orn

nrpys: Orn

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Long positively charged side chain (Orn, Lys, Arg)
Small clusters prediction:: Orn and hydroxy-Orn specific (Orn, OH-Orn)
Single AA prediction:: orn (Orn)

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEIGSIDK
Nearest Stachelhaus code(s):: Orn DVGEIGSIDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)