LOCUS       c00103_gnlPro..        15061 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GBFELEPG_202.
ACCESSION   c00103_gnlPro..
VERSION     c00103_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 10:17:03
            Original ID  :: gnl|Prokka|GBFELEPG_202
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15061
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15061
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1847:5061]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1848..5061
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..15061
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15061
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(9..1175)
                     /locus_tag="ctg103_1"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIEYAFLKDSDLTTDSNFMTRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQK
                     IPVANLAPFSEKFYRHYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHTDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGSMAAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLSCMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             complement(1295..1831)
                     /locus_tag="ctg103_2"
                     /transl_table=11
                     /translation="MNIFQEGNLQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNKGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             complement(1848..2189)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_3"
                     /sec_met_domain="AA_kinase (E-value: 2.8e-19, bitscore:
                     60.0, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGVAGVIDKDFSAAKLAEDIQADELVILTTVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDFVEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             complement(2358..2780)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_4"
                     /sec_met_domain="AA_kinase (E-value: 5.9e-13, bitscore:
                     39.3, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVALGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNPAMPLDTVVAMTQGSIGYWMQKALDDQFKHTNYPH
                     QAVALITQIIVNANDPTFKNPTKPIGPFYTFNEMQR"
     CDS             complement(2783..2914)
                     /locus_tag="ctg103_5"
                     /transl_table=11
                     /translation="MKSLTLNTLGKFTEAENRLHSIKAIMAATLGNLFIPSVDEGSK"
     CDS             complement(2874..3584)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_6"
                     /sec_met_domain="OTCace (E-value: 1.1e-41, bitscore: 133.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 7.6e-25, bitscore:
                     78.1, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDGIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPIQMLADFMTIKEKFGHLKGLTLAYVGDGRDNVADSLLVAGSMLGV
                     NVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIEQGVKGANIIYTDVWVSMGEND
                     WSERIKLLKPYTVTMKMMYMTGTPDDQLIFMHCLPAFHDRTTKVGKEIYEKYGLSEVEV
                     TDEVFNSQYAWQIY"
     CDS             complement(3832..4386)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_7"
                     /sec_met_domain="Amidinotransf (E-value: 1.2e-52, bitscore:
                     169.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLAIGISQRTSAAAITDLAHSLFGHSSYDTILAIKIPHNHAMMH
                     LDTVFTMINYDQCTVHPFILDKSGKIDIYVLEQDDHGEIKITPETDLIKVLKNYLHLSE
                     IDLIPTGGGDAIAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGILVHEIHSS
                     ELSRGRGGPRCMSCPLVREDL"
     CDS             complement(4334..4744)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_8"
                     /sec_met_domain="Amidinotransf (E-value: 9.8e-28, bitscore:
                     87.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLIAMPVNEMVKQIIAGIRKNEIQNATPSLADLAEDPDYPFYL
                     DPMPNVYFTRDQQAAIGNGMTINRMTFRARRRESLFMETVLKHHPDFKNANIPIWRDRY
                     THGRLEGGDELILNNHVFSNRYFSKNFRCRNH"
     CDS             complement(4876..5061)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_9"
                     /sec_met_domain="Amidinotransf (E-value: 1.6e-11, bitscore:
                     34.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEK"
     CDS             complement(5134..5988)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     73.6; E-value: 3.1e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg103_10"
                     /sec_met_domain="LysR_substrate (E-value: 2.3e-30,
                     bitscore: 95.9, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1e-23, bitscore: 73.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAEEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKFKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKHSNWITHLQLVWRKDQKVTPLMKRIIDS
                     LSR"
     CDS             6117..8390
                     /locus_tag="ctg103_11"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKENGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFTLSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSDLSDLPDKDVLALAGSATDKRNAGII
                     DIAIDEYLKENNIPVMDVEHFTPFTSDIGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIIKILDAGHRVYQRMTTWSLTK
                     LARTAELNMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFVSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(8458..8955)
                     /locus_tag="ctg103_12"
                     /transl_table=11
                     /translation="MRKQIISAAGIMLAVIGLGAATTQSVDAAVTNPVRQGKRLNLTRN
                     ATVYNRHGVKVGHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKSTVKVVN
                     RIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTVT
                     NH"
     CDS             9110..10600
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_13"
                     /sec_met_domain="PLDc_2 (E-value: 3.6e-27, bitscore: 85.3,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILTWDIIRRTIEVLWIINIAFAIWTVFRSRRSVVATWAWMLVLT
                     VLPGIGFILYLFFGRQLSHDEIFAIQEEQKKVQRHYLAEQRDMLKEHDLLPEKERLPRV
                     RMLSELNLNNDDAILTFDNQVKVFISGPELFDQMITDIKNAKKSVSLEFYTFYSNQLGH
                     RVLKALEEAAANGAKVRVIYDASGSRGTKASFFDHLRELGGEAQPFISTSKKHWFTTPR
                     LNYHLHRKLVIIDHHIGYIGGFNIGDQYVNKSPKFGHWRDTHLRVIGQSPILMEVRFAM
                     DWNTSIRRTNLPKFELKELKPFTVNRKDINDNKNVAMQIVSSGPDNQHYGIRRGYEGII
                     AGAKKYIYIQTPYLIPEESILEALIIAANSGIDVRIMVPCMPDHPFVYRATEYYAKYLV
                     AHGVKVYKYNDGFIHAKTMVSGSNISSVGSANQDFRSYTLNFEVNSFNYNPALTQELKK
                     IFEKDLDKCTLLTNDYFAQQSSWLKFKQYFSRLLSPIF"
     CDS             10730..11524
                     /locus_tag="ctg103_14"
                     /transl_table=11
                     /translation="LANRVKIGVLNLMHDKLDTQQRFARVLPDADLTFFYPRMHYQNRP
                     VPPEVAKTSQPLDLNQIKEFDGFIITGAPLDHLDFDQVTYIEEVRCLLQLLDKYKLQQL
                     YFCWGAMAALDYFYNIQKRILSKKIFGVFPHLIIEPHPLLNGLSQGFIAPHARYAEMDK
                     TQIMQDPRLTINSVDDNGHLFMVSSLEKPEQNFIFSHIEYGRKGLKKEYEREIAAHPER
                     HYKKPENYSLSNLLFQWKDTQKTFFNNWLTQVKKSKLVLLDK"
     CDS             11540..12469
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_15"
                     /sec_met_domain="PALP (E-value: 6e-70, bitscore: 226.3,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIYNSVTELIGNTPLLKLNRVVPDDAADVYVKLEFENPAGSIK
                     DRIALAMIEKAEREGNLKPGGTIVEPTSGNTGIGLAMVAAAKGYHIIIVMPETMSVERR
                     KLMKGYGAELILTPGADGMKGSIAKAEELVKEKGYFMPMQFENTENPNIHELTTGPEII
                     AAMNGIGKSVDAFVAGVGTGGTLSGIGHALRRENPSTKIFALEPTESPLLKDGKTGKHG
                     IQGIAAGFIPKNLDKDIYDDIITVSTDEAMATAREVAKNEGFLPGISAGANIHGAIEIA
                     KKLGKGHAVVTVVPDGGHRYLSTALFNA"
     CDS             complement(12613..13140)
                     /locus_tag="ctg103_16"
                     /transl_table=11
                     /translation="MAIDFSKYIASVKDFPNKGIVFRDITPILQDGELYRAATHELAEY
                     AKSRKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEYGSNSLE
                     MHKDAIKPGQRVVLCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLKGREKLPD
                     VDIYSLVQYHGA"
ORIGIN
        1 accttcttct aaaaataatc ataaaatgag actttacctt ttacaaagtc caacttttta
       61 attcgataat ctgtgatcaa accaagttta attgcggatt ccatagttaa acgtcctaat
      121 aagatttgag tccatgttgt aattggacca gagaaatcaa ctagttcatc ttcttttcgt
      181 tcacacttaa cttggtgatc ataattagtt aattgccaaa cgccaatatt ccatggacac
      241 tgatcatcat aattaacttc gatgttaaaa gtaccctctt gcaatgggcg catgcatgac
      301 aagacttttt ggaaatcaat aattctactc atcatatatg gatgaagttg aatatccaat
      361 tcattttgct ctggaaaaag ttcagccaat aaagacttct caggcaatgt catacaaaac
      421 tctttaattg accctatatg agctgccata gagcctaata tgcttaataa tccttgaggc
      481 gtaattgaat ataattcatc agccataaaa cagttatcaa ttatgcgata aatcaagtag
      541 ctcatcggcc gaccagcttc atcgaagtaa acagcaatct ctcgatgatg ataataatca
      601 tctaatctat tccaccacca agcttctctg atgatcgtat ttctttcatc gtcagtatgc
      661 aactgacgtt catataattg aatcacacca ttttgaacaa tcaaatcatt ccattttcca
      721 cgaattatct tacctttgcg tggtaatctg aaagaagcaa gtgcagcccc cgaaaagcga
      781 tattcttttt ggtaaatact attgctaaaa ccataatgac gataaaattt ttctgaaaat
      841 ggagctagat ttgcaactgg gattttttga tcatgcaaat caaaaagaat ttctttcatt
      901 aatttagata tatgtccacg tcctctgtat tcaggatatg atgccacata accaatacct
      961 gccagtggaa catgatgacc aaatatctca gctttaaact tattgaccat catataactg
     1021 gtcaattttt cttgatcaaa atatccatat ccatcactat gatcatatcg ggtcataaag
     1081 ttactatctg tagtcaaatc agaatctttt aaaaaagcat attcaatcaa tgaagcaatt
     1141 tgttttaaat tgtcttggtt tttctttaat ttcatagttt tccttacaat atatattcat
     1201 aactttactt atattttaga acattttatg tatttttcgt tagctttttt aagatttaaa
     1261 tgaaaaaacg ggatgattag cctcccatcc cgttttaatt atttacatac ttcgcatata
     1321 aactagaaat gtatctttgc atctcttcta ctgagtgtcg ccgtgatcga gcacactctt
     1381 tagcagggcg attgcataaa tagcagcggc gactagagta ttcaagctct tggcgtgaaa
     1441 gtgcagtttt ccctttaatt aatacatcgg catcaaataa tcgtcctatt ttattatttt
     1501 cttcaaataa aattgtagat aatttaacta ctttgctaga ttctcgcaaa acatagaaat
     1561 tttcacatcc agcatcatta tttaatgctt ttactaattt atagtcatat cccttattct
     1621 gccatatttc ttctaattgt ttaattccgt aatcaaataa tttgattaaa tatcgattat
     1681 ttttaattgg ccccgggata tttaagttta tatcaaccaa agtcgcatca ggatactttt
     1741 taaaaatagc ttgctgcaaa gctacacgat aatcttttcc agctaatacc tgagcaatat
     1801 tttgcagatt tccttcttga aaaatgttca tttatatctc accgcagtta attataaaca
     1861 attgtaccta ctccatcatc aagtttactt gcatttctta aagaagtaat aattgcagtc
     1921 tttcctgttt tctctacgaa atcaatgaca gcttcaattt ttggcttcat gctgcctgcg
     1981 gcaaattggc cagcttctag atacttcttt aattgatcaa tctttatttt tccaatagga
     2041 gcttgatcag gttgattata gttcacgtag gcattgtcaa cagtagttag aataactaat
     2101 tcatctgctt gaatatcttc agctagtttt gcggcactga agtctttatc aattactcct
     2161 gctacgccct gcaaactatc gtctttcact acgacaggaa ttccaccacc tccggcagca
     2221 ataggaacaa acttgctctt tagtaaagtg tcaatgactg gtgcattaat aattttaacg
     2281 ggctttggag aagaaactac ttgacgatag cctcgacctg catcttgctt ataagtatat
     2341 tcaggatgat agatttttta cctctgcatt tcgttaaatg tataaaatgg gccaattggt
     2401 ttagttggat tcttaaaagt tggatcattc gcattaacta ttatctgagt aattaaagca
     2461 acagcttgat gtggataatt tgtatgttta aattgatcgt ctaaggcctt ttgcatccaa
     2521 tagccgatac tgccttgagt cattgctact actgtatcaa gcggcatagc gggattatct
     2581 ttacttgaac ctttgtattg ttgcaaaagc aaattaccaa cctgcgggcc attaccatga
     2641 acaatcgcta cctgatcacc attttcaatc attttagcaa caaccttcat tgtcttttta
     2701 acctgctttt cttgggcagc tgcactatta tcacctgctt caatagcatt gccacccaaa
     2761 gctacaacta ttcttttcat ctttatttac ttccttcatc aactgacgga ataaacaaat
     2821 tgcccaaagt agcggccatt attgctttga tagaatgcaa tctattttcc gcttcagtaa
     2881 atttgccaag cgtattgaga gttaaagact tcatctgtaa cttccacttc acttagacca
     2941 tatttttcat aaatttcttt gccaacttta gtagtgcgat catgaaacgc aggcaaacag
     3001 tgcataaaga ttagttgatc atccggggtg cctgtcatat acatcatctt cattgtaacc
     3061 gtgtaaggct ttaacaattt gattctctca ctccagtcat tttcacccat tgatacccag
     3121 acatcagtat aaataatatt tgcaccttta acgccttgtt caatgtcatc agtaatcaaa
     3181 tttcttgatc cagaatcttt ggcaaaacct tctgcaattt tttgtacatc agggtgagtg
     3241 aataaaggct ttggcgtaac tatgtgtaca ttaactccaa gcatgctgcc agccactaaa
     3301 agactgtcgg caacattatc acgtccatcg cctacataag ctaaagtaag tccctttaaa
     3361 tgtccaaact tttctttaat agtcataaag tcagccaaca tttggatcgg atgccattta
     3421 tctgttaaac cattccaaac agggacacca gaatatttag ccaaatcttc tacatctttt
     3481 tgagcaaaac cgcgatattc aatgccatca aacatactgc ccaaaacctt tgcagtatct
     3541 tcaatacttt cctttttacc taaatgaatt tcaccagcac ccatatattc aggatttgcg
     3601 cctaaatcat tgcatgcaac tacaaaggct gaacgtgttc ttgttgaaga tttttcaaat
     3661 aaaagagcta tattctttcc ttttaaatat tcatgcggaa tattttcttt agttccttca
     3721 aatgaagtgc gaaatcaatt agatagttaa gctccgctgg agtatagtct ttgcatttta
     3781 ataaacttct gccttgaaac acattttgta aatatttcat tttgacgcct cttacaaatc
     3841 ttcacgaaca agtggacatg acatacatct tggacctcca cggccacgag aaagctcact
     3901 tgaatgaatt tcatgaacta aaatgccatg ctttcttaac aaatcatttg atacataatt
     3961 acgatcatat gtaacgactt cacctggcgc aatagccaaa gtattcgagc catcattcca
     4021 ctgctctctt ggggctgcaa ttgcatcccc acctccggtt ggaattaggt caatctccga
     4081 taagtgcaaa taattcttta acactttgat caaatcagtt tctggggtaa ttttaatctc
     4141 accatgatca tcttgctcta aaacataaat atcaatcttt cctgatttgt ctaaaataaa
     4201 aggatgaacg gtacactgat cataattaat cattgtaaag actgtatcca gatgcatcat
     4261 ggcatgatta tgtggtattt taattgctaa aattgtgtca taactagaat gaccaaacag
     4321 gctatgagca aggtcagtga ttgcggcagc ggaagttctt tgagaaatac cgattgctaa
     4381 aaacatgatt gtttaaaatc agctcatcgc caccttctaa acgtccatga gtgtaacgat
     4441 cacgccaaat aggaatattg gcatttttaa agtcgggatg atgctttaaa acggtttcca
     4501 taaataatga ctcacgtctt ctagctctaa acgtcattct attaatagtc atgccattac
     4561 caatagctgc ttgttgatca cgagtaaaat acacatttgg cattggatcc aaataaaatg
     4621 gataatctgg atcttcagct agatcggcta atgaaggagt tgcattttgt atttcatttt
     4681 ttctaatacc agcaattatt tgcttaacca tttcatttac tggcattgct attaaatagt
     4741 ccatcagtaa ttgatgtaat ggatcttctt ttttatattg gattcttcta ataattgatc
     4801 tacaaatttt gtacggacat cttcattagt caaagagtga gctaataaat cttctaaata
     4861 aacgacatga actccctatt tttccaaagt gtgggcaaaa tagtcatgct ctttttgagc
     4921 tatttttaaa tatggaatat cgtcaattaa cattcgattt aagatatccg gtgaaagatt
     4981 ttctaattct cttcccggtc gatgcagcat aactgtttct aatttgccaa tttcggaata
     5041 aacatgaatt aagtcagtca ttatagcgcc tcctaattca aattatgtat ctgcttacaa
     5101 taattatgga tcaattaggt agaagttaca atcttaacgg cttagtgaat ctattattct
     5161 tttcattaaa ggcgtcacct tttgatcctt gcgccacact aattgcaaat gcgtaatcca
     5221 attactatgt ttaataggaa taagatcatc aggtgcatac gtagaagcaa tagattcagg
     5281 aacaagagca atccccattt ttctcttcgc ccaagtaatc gctgttctag aatcatcaca
     5341 tttaacagca taaaatggct taatcccatg atgagcaaaa gtctggttaa aaatttcttc
     5401 aaatcttcga taaataatga ggggctgctc atttagatct ttaatcctta attccgtctt
     5461 atccttaaat ttgggatcaa cagtaactgc catcattctt tcagtagtta aagtttttgc
     5521 atttaagcca ttacgattat aaggcgtacg cacaattcct aaatcgattg tcttcttttc
     5581 caatttatcg ataatgccaa aggtattatc ttcataaata tcaaagttga tttccggata
     5641 aaacttagtt aaatcttgaa aacttttcat aggaattagt ccagttgatg atgaagccat
     5701 gcctattgca atcgtgccta gttcacctga aacagtttta tgaacctgat ttttcacgct
     5761 ttctgataaa gagagaattt cactagcata gctctgcaaa atttgtccag catctgttaa
     5821 ttcaattcca tgagcagtac gcttaaataa ttgtgctcct agttctattt ctagttgctt
     5881 taattgataa ctcagcggcg gttgtgcaat gtatagtctt ttagctgctg aagtgatttg
     5941 cttttcttca gctactacta aaaagtagcg taattgttta atattcatta ataatctatc
     6001 ctttttattt tagttgtatc tcttattaaa aatttctata tcttatattt taatttagta
     6061 ttttcattca aacaacatat gtgctacttt attaaggtag atttggaggg aataaaatgt
     6121 ctgaaaaatt tcatggctta actcaagccg aagcagataa gagacttaaa gaaaatgggt
     6181 taaacgaagt acctgaaccc gaatacaact tttttaagga atttctatca aaattatgga
     6241 atctttctgc ctggattcta gaaggtgcct taatcctcga atgtatctta ggcaaatgga
     6301 ttcaatcttt gttcgtcttg ttgatgcttc tttttgcggc ttttaacggt gcatccaaga
     6361 agaaacagtc acggcgggta ttaaatacca tttcacataa gctaacccct aaggtagctg
     6421 tagaacgcga tggtaagtgg atcaaaattg actctaagca attagttaga ggcgacttaa
     6481 tctcacttca acgtggagat gtacttgcag ccgatgtaaa aatggttagc ggtaagatcg
     6541 cctgtgatga aagctcaatt accggtgaat ccaagcccgt taaaaagaac attgatgaca
     6601 cagcttatgc tggtactact gttgttgaag gcgatggatt agcaattgtt actgcaactg
     6661 gtaaagattc aagaagtggt aagaccatta acttgatcaa caattcagct gcacctggtc
     6721 acttgcaaca acttttaact aagattattt actacctttg cctacttgac ggtgtactta
     6781 ccttagttat tatcattgct tcattcttta agggtggtaa ttttgatacg tttatcaaca
     6841 tgttgccatt cttagccatg atgttcatcg cttcaattcc ggttgcgatg ccgtcaacct
     6901 ttacattgtc caattcattt gaagcaaccc gtttaagtaa agaaggcgtc ttaacagctg
     6961 atttaactgg tatccaagat gcagctaact taaacttgct tttacttgat aagacgggaa
     7021 caatcactga aaacaaaact gcagttgcta gttggagcga tttaagcgat ttgccagata
     7081 aagatgtact tgctttagcc ggtagtgcaa ctgataagcg caatgcaggt atcattgata
     7141 tcgccattga tgaatactta aaagaaaaca atatccctgt catggacgtt gaacacttta
     7201 ccccatttac ttctgacatt ggctattcta tggctgaagt agatggtcac aatgttaagt
     7261 taggttcatt taagcaactt tcattaatcg ataagaatgc aaatgaagca gttgaaggca
     7321 tcaattttaa agctggacgc tcagttgccg tgttaattga tgacaaactt gcgggagtat
     7381 ttatcttaca agataaagta agaaaggact ctaaggctgc tttagcagaa cttaaaaaac
     7441 ggggcgtacg tccaatcatg ttaactggtg ataatcaaag aactgccgca gcagtcgctg
     7501 aacaagttga tttaactggt aacgttatct ctattcatga ctttgatgaa agcaccgata
     7561 ttgatgaatt agcagggatt gccgatgttt tacctgaaga taaacttaag atggttaaat
     7621 tcttccaaga aaaaggttat atcgttggta tgactggtga tggtgttaac gactctcctg
     7681 ctttaaagca agctgaagtt ggtattgctg tttctaacgc tgccgatgtt gccaagcgtt
     7741 caagtaagat ggtgcttcta gatgatggct taagctctat tattaaaatt cttgatgctg
     7801 gtcaccgtgt atatcaacga atgactactt ggtcacttac taagctcgcc agaaccgccg
     7861 aattaaatat gcttttaacc ttcggctatc tcttcttcaa ctatattcca atggcattaa
     7921 atgctatggt tatttacaca atcatgaata acatggttac catgatgatt ggtaccgacc
     7981 gtacccatat tacttacaaa ccagaaaatt ggaatatggc aaggttagcc aaaatcgcat
     8041 tctctcttgc tgcaggttgg acagttatcg gtatcgcttt tgtcagctac ctcaacatgc
     8101 atggctggag tcacaattct atctctacca tggtctatgt ttacttagtt ctaagtgcaa
     8161 tgttaattgt attaattact agaactcgta aatacttctg gcaagattac ccatctaaac
     8221 ttgtaggtat tgttcaaatt gccgatgtcg cattaacctt tattttagct ttatgcggtt
     8281 tagcaatggc tcaaattagt tggcaaaact tattaattac cgttgtggtt gcattaattg
     8341 cagcaattat tattgatttg atttatcaac cagtaatgaa aaacagataa ttaacttaaa
     8401 acaaaaacac tctgaaaact acattactac aatgtagttt tcagagtgtt tttttgatta
     8461 atgattagta actgtagtca aggcattcaa agccttaaca tattcaccat cagcaatttt
     8521 gataaatggt ttttcattaa tttctttatg gcctaaatag ttaaccttag caccacgctt
     8581 taaaaatttg cctgggattt tttcaccatt ctcatcataa acaaaggaat gctttttgat
     8641 tctattaact acttttacag tagacttcat atatggcaag aaggcttctt ccttaacaaa
     8701 tctattttta cgaatcttta cataagtatt accattaatt acttttatgg cacgtacttt
     8761 gtaaagcttt ccctttctta aatgtccaac tttaacacca tgtctattat aaacagtagc
     8821 atttctagtt agatttaatc tcttaccttg tctaactgga ttagtaacag ctgcatcaac
     8881 gctttgtgta gttgctgcgc ctaatccaat aactgctaac attatacctg cagcagaaat
     8941 aatttgtttt ctcatcataa tccacccccg tagtgtttat accattctcc atcccttatt
     9001 ttatcaaaaa ttatcgaatt ggaagcattt tttactcatc tgttttataa ctatttgctt
     9061 aattctgcta aaattattta taacactact tacaagggag taattattca tgattttaac
     9121 ttgggatata atccgtagga ctatcgaagt cttatggatt atcaatattg cgtttgctat
     9181 atggacggtc tttagaagtc gccgcagcgt tgttgcaact tgggcatgga tgcttgtatt
     9241 aaccgttctg cccggtatcg gttttatcct atatcttttc tttggtcgtc agctttcaca
     9301 tgatgaaatc tttgctattc aagaagagca aaaaaaggta caaagacatt atttagctga
     9361 gcaacgcgac atgcttaaag agcacgatct tctacctgaa aaagagcgtc ttccacgagt
     9421 aagaatgctt tcggaactaa atcttaacaa cgatgatgcg attttaactt ttgataatca
     9481 ggtcaaagta tttatttctg gaccagaact ttttgaccaa atgattactg atatcaaaaa
     9541 tgccaaaaaa tctgtcagct tagaatttta tactttttat tctaaccaat tagggcatcg
     9601 tgttttaaaa gccttggaag aggctgcagc taatggtgct aaggtaagag taatttatga
     9661 tgcctctgga tcaagaggca ctaaggcaag cttttttgac catttaagag aattgggcgg
     9721 cgaagctcag ccatttattt ccacttcaaa aaagcactgg tttactaccc cacgactcaa
     9781 ttaccactta catagaaaat tagttattat tgaccaccat attggctata ttggcggatt
     9841 taatattgga gatcaatatg tcaataaatc accaaaattc ggtcattggc gggataccca
     9901 tttacgtgta attgggcaat caccaattct aatggaggtc cggtttgcaa tggactggaa
     9961 cacgtcaatc agaagaacaa atttacctaa atttgaatta aaggaactta aaccatttac
    10021 tgtcaatcga aaagatatca atgataataa aaatgtcgct atgcaaattg tttcctcagg
    10081 acctgataat caacattacg gcatcagacg aggctatgag ggaattattg caggagctaa
    10141 aaaatacatt tatattcaaa cgccttattt aattcccgaa gaatcaattc ttgaagcctt
    10201 aattatcgct gctaacagcg gtattgatgt tcgaattatg gttccttgca tgcccgatca
    10261 tccatttgtt tatcgtgcta cagaatacta tgctaagtat ttagtagccc atggcgttaa
    10321 agtatacaaa tataatgatg gttttattca tgcaaaaact atggttagcg gttctaatat
    10381 ttcttcagtt ggttccgcca atcaagattt ccgaagctat acattaaact ttgaggtaaa
    10441 ctcattcaac tacaaccctg ctttaactca agaattaaag aaaatttttg agaaggactt
    10501 agataaatgt acccttttaa ctaatgacta ctttgctcaa caatcatcat ggttaaaatt
    10561 taagcaatac ttctcaagat tattatcacc tattttttaa tgaaaagccc tctatcggtc
    10621 tatccgatgg gggttttact ttgtatttta aaaatgcagt tttatttctt tacttatttt
    10681 tataagttat ataataatga taactattaa aaagtaagga ggataaaact tggctaatag
    10741 agtaaaaata ggcgttttga atttaatgca cgataagtta gatactcaac aaagatttgc
    10801 acgcgttttg ccagatgcag acctgacttt cttttatcca cgtatgcatt atcaaaatcg
    10861 tcctgtccca cctgaagttg caaaaacttc ccagccatta gatcttaatc aaatcaaaga
    10921 gtttgatggc tttatcatta cgggcgcacc tttagatcat cttgattttg atcaagttac
    10981 ctacatcgag gaagtccgat gtttgctcca actattagat aaatacaagt tgcagcaatt
    11041 atatttttgc tggggtgcaa tggccgcttt agattatttt tacaatattc aaaaaagaat
    11101 tttatcgaaa aaaatctttg gtgtttttcc tcatttaatt atcgaaccac atcctttatt
    11161 aaatggactc agccaaggat ttatcgctcc acatgctcgt tacgctgaaa tggataaaac
    11221 acagattatg caagatccac gattaaccat taattcagtt gacgataatg ggcatctatt
    11281 tatggtctct tctttagaaa agcctgagca aaattttatt ttctctcata tcgaatatgg
    11341 ccgaaaaggc cttaaaaaag aatatgaaag agagattgct gcacatccag agcgacatta
    11401 taagaagcca gaaaattatt cattatcaaa tctattgttt caatggaaag atactcagaa
    11461 aacatttttc aataactggc taactcaagt taaaaaaagc aaattagtat tattagataa
    11521 ataaaacgag gtatacatta tgtctacaat ttataattca gttacagaac ttatcggcaa
    11581 cactccatta cttaagttga atcgcgttgt acctgacgac gcggcagatg tctatgtaaa
    11641 gttggaattt gaaaacccag ctggttcaat taaagacaga attgctttag ctatgatcga
    11701 aaaagctgaa cgtgaaggca acttaaagcc aggtggcaca attgtagaac ctacttcagg
    11761 caataccggt atcggtttag ccatggttgc tgcagctaag ggctatcaca ttattattgt
    11821 tatgccagaa actatgagcg ttgagcgtcg taaattaatg aagggctatg gtgctgaact
    11881 tattttgaca ccaggtgcag acggtatgaa gggttcaatt gctaaggccg aagaattagt
    11941 taaagaaaaa ggctacttca tgccaatgca atttgaaaat acagaaaatc ctaatattca
    12001 tgaattaact actggtccag aaattattgc cgcaatgaat ggtatcggca aatccgttga
    12061 tgcctttgtt gctggtgttg gtactggtgg tactttatca ggaattggac atgcacttag
    12121 gcgtgaaaat ccatccacta agatatttgc acttgagcca actgaatctc cactcttaaa
    12181 agatggaaaa acaggtaaac atggtatcca aggtattgcc gcaggtttca tccctaagaa
    12241 tttagataag gatatctacg atgatataat tacagtttct actgatgaag caatggctac
    12301 agctcgtgaa gtagctaaaa acgaaggctt cttacctggt atttcagctg gtgcaaacat
    12361 ccatggtgca atcgaaattg ctaaaaagtt aggcaaggga catgctgtgg ttactgtagt
    12421 tccagacggc ggtcatcgtt acctttcaac tgcattattt aatgcttaaa acttaatttc
    12481 tgtaaacaaa tactcctaag taaaatttcc ttaggagtat tatttttatt tctgttgatt
    12541 gtgcaccagt caatgctggt acaacacttt tagtataatg acctttacta attagatcaa
    12601 tattgaattt atttaagcac catgatattg cactaagctg taaatatcaa catcaggcaa
    12661 cttttctcta ccctttaaat caggcaattc aatgtaaaat gcagcaccta caagcttacc
    12721 accaagattt tcaattaatt ccttagaagc tcttaaagta cctgcagtag ccattaaatc
    12781 gtcacagaga acaactcttt ggccaggctt aattgcatct ttatgcattt caaggctatt
    12841 tgaaccgtat tccaagtcat atgaagcacg ttcaacttct cttggcaact tatgtggctt
    12901 tcttgctgga acaaaaccta agcctaactc agttgcaaca ggacagccta caataaagcc
    12961 acgtgcttca ggacctacga ttacatctgc ctttctactc tttgcatatt ctgccaattc
    13021 atgagtagca gcacgataca attcaccatc ttgcaaaata ggtgtaatat cgcgaaagac
    13081 aattccctta ttaggaaagt ccttaacact tgcaatatat ttactaaaat caatcgccat
    13141 aagaagaaaa acctccataa ttctgtgcgt ttgtattcaa acacttttga cttgtatatt
    13201 ttaccaaaga tttgttataa aagtactgaa atcttgatat ttatctatct ttttaccaaa
    13261 ttattaacat atgtaattaa tttttgagta ggcatcgttc ttagttgatt aataaattta
    13321 atttgtgaac tcgttgccat taaatattta gaagctgtca atggttgctt ctttggatta
    13381 gactcaccaa ctaatttttg atcgtctaat ttaacaaaac ctaattcaaa gaatactcgc
    13441 aaaataaaca atacactatc ataatccaaa cctagatatg gtgctacagt gcgatagtct
    13501 tcaggcttta atgctggatg ggcataaata tactttaaca cttttccgaa ataactcttt
    13561 gctggaattt gttcaacagg taactgatct aataaaaagc gtaaataaat ttgttgataa
    13621 tctttttcta aagctgcatt taattccact tgattgcgag gcacatcaag caaagctact
    13681 gtttcacccg attgatcata atctttaacc aagctaattt tatcatcatc aatttgaagg
    13741 cgattcttaa caattggaat attctttttg tcaaaaagca aataacgatc tgcaaggccc
    13801 atgacaaatt tctcttgtct taaatcaatt actgatgttg gcacagctaa ttttggggat
    13861 gcaaaggcta ttccttccat gatgccttgc aaagatactt gtttgcgata agtattcaaa
    13921 gagagagtaa caaagatttt tgaaataaat ggtaacaaat tattattcaa ataatcctta
    13981 ttaaatccca caattgctaa attgccgtct tttttattag ctgttaattt aacatgattc
    14041 ttatcttttc ctattttgaa aaagtgtgta atagttggat ccgaaatact aaaaattggc
    14101 tgcggatcac cagtaccaaa tggtcccact tgattaattt gagccaaagt ttgaggtgat
    14161 aagtcatgca taggcaattc catatcgtac tctttagtct ctaaaccacc gtcaacatga
    14221 aaatcggctt caaacttttt ccgtaggtca tttactttat cttcttccat ggataaacca
    14281 caagcaaaat catgacctcc aaatttggtc aatagacttt cttttaacgg attaagagca
    14341 tcaaataagt taaaaccaat gaatgaacga cctgatccct taatctcccc ttcatcgttt
    14401 ttagttaaaa caattgttgg tttatgcaat ttttccacta tcttgttagc aacaagcccc
    14461 aaaactcctt catgaaaatc aggatcatat aaaactaaag tattttgctt ttgccaacta
    14521 ttttcacgaa ctaattccat gcagcgatcg taaacctcag tagttagctc tttacgctta
    14581 ttatttaagt cttcaatctg atctgcgatc ttctgtgcct caagatcatc atcactaagc
    14641 aaaagctcta ctgccagatt agcattagcc aaacgtccaa cagcattaag tctaggagca
    14701 atattaaagc ctacatctgt ctcattgatc gtttctagcg ttaaaccggc atttttgata
    14761 agcgctctta agcccggtcg ttcggtttga ttaagaacat ctaacccacg ttttacaata
    14821 atatggcctt caccagtaac tttaaccatg tcaccaatag taccgatcat tgctaaatct
    14881 agcaattctg gtacaggatc ctgcataagc tcacgacaaa tcgtataagc tacacctgca
    14941 ccacaataat catcaaaagg atattcttga ccaggataat tacagtgaac aattgcataa
    15001 gcatctggct tattttcttg aaaagtatgg tgatccgtaa taatagtatc aacgccatat
    15061 t
//
