LOCUS       c00076_gnlPro..        16018 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AAINNGGK_158.
ACCESSION   c00076_gnlPro..
VERSION     c00076_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 10:27:42
            Original ID  :: gnl|Prokka|AAINNGGK_158
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16018
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16018
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3160:6018]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3161..6018
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..16018
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16018
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(41..460)
                     /locus_tag="ctg76_1"
                     /transl_table=11
                     /translation="MLERKLLPLLAMVLALGLSGLTTHVKAADTTYGNGNGAVVTVPKK
                     MQGTWYSYDSNAHSGRKITFTAHTVNGKIIYTQDKSIISDYFNGNIQDQAGFDRATKNW
                     MSGQTTKMKNNLFYEINPWISFENWSLYRVMPLTI"
     CDS             complement(537..1142)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_2"
                     /sec_met_domain="LysR_substrate (E-value: 8.9e-19,
                     bitscore: 58.2, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEEAVIKDFILLAKKVY"
     CDS             complement(1145..1306)
                     /locus_tag="ctg76_3"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLSVVVSGINVVISLLIMFNKYQIRKDKKQIADE
                     GHAPLDEN"
     CDS             complement(1322..2488)
                     /locus_tag="ctg76_4"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIEYAFLKDSDLTTDSNFMTRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQK
                     IPVANLAPFSEKFYRHYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHTDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGSMAAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLSCMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             complement(2608..3144)
                     /locus_tag="ctg76_5"
                     /transl_table=11
                     /translation="MNIFQEGNLQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNKGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             complement(3161..3502)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_6"
                     /sec_met_domain="AA_kinase (E-value: 3.1e-19, bitscore:
                     60.0, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGVAGVIDKDFSAAKLAEDIQADELVILTTVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDFVEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             complement(3671..4093)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_7"
                     /sec_met_domain="AA_kinase (E-value: 6.3e-13, bitscore:
                     39.3, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVALGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNPAMPLDTVVAMTQGSIGYWMQKVLDDQFKHTNYPH
                     QAVALITQIIVNANDPTFKNPTKPIGPFYTFNEMQR"
     CDS             complement(4096..4896)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_8"
                     /sec_met_domain="OTCace (E-value: 4.8e-51, bitscore: 163.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 1e-24, bitscore: 77.8,
                     seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDGIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPIQMLADFMTIKEKFGHLKGLTLAYVGDGRDNVADSLLVAGSMLGV
                     NVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIEQGVKGANIIYTDVWVSMGEND
                     WSERIKLLKPYTVTMKMMYMTGTPDDQLIFMHCLPAFHDRTTKVGKEIYEKYGLSEVEV
                     TDEVFNSQYAWQFTEAENRLHSIKAIMAATLGNLFIPSVDEGSK"
     CDS             complement(5144..5698)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_9"
                     /sec_met_domain="Amidinotransf (E-value: 1.3e-52, bitscore:
                     169.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLAIGISQRTSAAAITDLAHSLFGHSSYDTILAIKIPHNHAMMH
                     LDTVFTMINYDQCTVHPFILDKSGKIDIYVLEQDDHGEIKITPETDLIKVLKNYLHLSE
                     IDLIPTGGGDAIAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGILVHEIHSS
                     ELSRGRGGPRCMSCPLVREDL"
     CDS             complement(5646..5864)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_10"
                     /sec_met_domain="Amidinotransf (E-value: 7.1e-14, bitscore:
                     42.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINRMTFRARRRESLFMETVLKHHPDFKNANIPIWRDRYTHGRL
                     EGGDELILNNHVFSNRYFSKNFRCRNH"
     CDS             complement(5854..6018)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_11"
                     /sec_met_domain="Amidinotransf (E-value: 3.3e-09, bitscore:
                     26.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDY"
     CDS             complement(6091..6945)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     73.6; E-value: 3.1e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg76_12"
                     /sec_met_domain="LysR_substrate (E-value: 3.2e-30,
                     bitscore: 95.6, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.1e-23, bitscore: 73.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAEEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKFKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYVPDDLIPIKHSNWITHLQLVWRKDQKVTPLMKRIIDS
                     LSR"
     CDS             7074..9347
                     /locus_tag="ctg76_13"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKENGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFTLSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSDLSDLPDKDVLALAGSATDKRNAGII
                     DIAIDEYLKENNIPVMDVEHFTPFTSDIGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIIKILDAGHRVYQRMTTWSLTK
                     LARTAELNMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFVSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(9415..9912)
                     /locus_tag="ctg76_14"
                     /transl_table=11
                     /translation="MRKQIISAAGIMLAVIGLGAATTQSVDAAVTNPVRQGKRLNLTRN
                     ATVYNRHGVKVGHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKSTVKVVN
                     RIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTVT
                     NH"
     CDS             10067..11557
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_15"
                     /sec_met_domain="PLDc_2 (E-value: 4e-27, bitscore: 85.3,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILTWDIIRRTIEVLWIINIAFAIWTVFRSRRSVVATWAWMLVLT
                     VLPGIGFILYLFFGRQLSHDEIFAIQEEQKKVQRHYLAEQRDMLKEHDLLPEKERLPRV
                     RMLSELNLNNDDAILTFDNQVKVFISGPELFDQMITDIKNAKKSVSLEFYTFYSNQLGH
                     RVLKALEEAAANGAKVRVIYDASGSRGTKASFFDHLRELGGEAQPFISTSKKHWFTTPR
                     LNYHLHRKLVIIDHHIGYIGGFNIGDQYVNKSPKFGHWRDTHLRVIGQSPILMEVRFAM
                     DWNTSIRRTNLPKFELKELKPFTVNRKDINDNKNVAMQIVSSGPDNQHYGIRRGYEGII
                     AGAKKYIYIQTPYLIPEESILEALIIAANSGIDVRIMVPCMPDHPFVYRATEYYAKYLV
                     AHGVKVYKYNDGFIHAKTMVSGSNISSVGSANQDFRSYTLNFEVNSFNYNPALTQELKK
                     IFEKDLDKCTLLTNDYFAQQSSWLKFKQYFSRLLSPIF"
     CDS             11687..12481
                     /locus_tag="ctg76_16"
                     /transl_table=11
                     /translation="LANRVKIGVLNLMHDKLDTQQRFARVLPDADLTFFYPRMHYQNRP
                     VPPEVAKTSQPLDLNQIKEFDGFIITGAPLDHLDFDQVTYIEEVRCLLQLLDKYKLQQL
                     YFCWGAMAALDYFYNIQKRILSKKIFGVFPHLIIEPHPLLNGLSQGFIAPHARYAEMDK
                     TQIMQDPRLTINSVDDNGHLFMVSSLEKPEQNFIFSHIEYGRKGLKKEYEREIAAHPER
                     HYKKPENYSLSNLLFQWKDTQKTFFNNWLTQVKKSKLVLLDK"
     CDS             12497..13426
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_17"
                     /sec_met_domain="PALP (E-value: 6.6e-70, bitscore: 226.3,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIYNSVTELIGNTPLLKLNRVVPDDAADVYVKLEFENPAGSIK
                     DRIALAMIEKAEREGNLKPGGTIVEPTSGNTGIGLAMVAAAKGYHIIIVMPETMSVERR
                     KLMKGYGAELILTPGADGMKGSIAKAEELVKEKGYFMPMQFENTENPNIHELTTGPEII
                     AAMNGIGKSVDAFVAGVGTGGTLSGIGHALRRENPSTKIFALEPTESPLLKDGKTGKHG
                     IQGIAAGFIPKNLDKDIYDDIITVSTDEAMATAREVAKNEGFLPGISAGANIHGAIEIA
                     KKLGKGHAVVTVVPDGGHRYLSTALFNA"
     CDS             complement(13570..14097)
                     /locus_tag="ctg76_18"
                     /transl_table=11
                     /translation="MAIDFSKYIASVKDFPNKGIVFRDITPILQDGELYRAATHELAEY
                     AKSRKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEYGSNSLE
                     MHKDAIKPGQRVVLCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLKGREKLPD
                     VDIYSLVQYHGA"
ORIGIN
        1 tttagtgctt gcagaagata cattaagttc agagttaaac ttatattgta agaggcatta
       61 ctctatatag actccaattt tcaaaactaa tccatggatt aatctcataa aatagattat
      121 ttttcatctt agttgtttga cctgacatcc aatttttggt agctcgatca aaaccagcct
      181 gatcttgaat attgccatta aagtaatcgc taataattga tttgtcttga gtgtaaatga
      241 tttttccatt aaccgtatgc gcagtaaaag taatttttct accgctatgt gcattactat
      301 catatgagta ccatgtcccc tgcatcttct taggcacagt cacaaccgct ccgttaccat
      361 taccataagt ggtgtcagcc gcctttacat gcgttgttaa tccgctcaag cctaaagcca
      421 gtaccatggc taacaaaggc aataattttc tctctagcat aaaatcatct ccagttgtaa
      481 aattatggat tcgctttcat tgttaatttt acagtatttt gctgttccaa gatagattaa
      541 tatacttttt tagctaacaa aataaaatct ttaattactg cctcttcatt ggtataaaaa
      601 gctgcaatct tttgccacat ttgttgtcca ttagacaata aaaacaatcg ttgtaaagta
      661 tcattactaa ttaaactggc ggttgcttca ttcattaaaa aatatcctga tccagaagct
      721 actaacaatg ctgcctcttc tacggaattt gaagcaatga atgggcttct aatctgataa
      781 atatctttaa ataaatggag ttctgcagcc tcttcttcag gcttagctac aataaaacag
      841 gttaaatcag ctagatcatc tttattgatc atctgaacac cgctaggata actacccttt
      901 tgcaaaatag ccattactgc ttcctgacct aagatttctt tcttaaaatc gagctgatca
      961 tcgcgcaaat cactaatcgc taaatcaact tcatttttgg ctaatttatc aaaagcttca
     1021 tcgtgtccca ttccaattaa ttcaatttct acatcagaat gtttttgctt aaattggtct
     1081 acaattcgat ctaattgtct tctaccaagt tggttaaagt atgctattct caattttttc
     1141 atagttaatt ttcatccaat ggggcatgac cttcatctgc tatttgtttt ttatcttttc
     1201 taatttgata tttgttgaac ataatcaata gcgaaataac cacatttatt ccactaacta
     1261 ccacgcttaa aaattttagt aatctaactt tcttttgctt actcattttg gataccttct
     1321 tctaaaaata atcataaaat gagactttac cttttacaaa gtccaacttt ttaattcgat
     1381 aatctgtgat caaaccaagt ttaattgcgg attccatagt taaacgtcct aataagattt
     1441 gagtccatgt tgtaattgga ccagagaaat caactagttc atcttctttt cgttcacact
     1501 taacttggtg atcataatta gttaattgcc aaacgccaat attccatgga cactgatcat
     1561 cataattaac ttcgatgtta aaagtaccct cttgcaatgg gcgcatgcat gacaagactt
     1621 tttggaaatc aataattcta ctcatcatat atggatgaag ttgaatatcc aattcatttt
     1681 gctctggaaa aagttcagcc aataaagact tctcaggcaa tgtcatacaa aactctttaa
     1741 ttgaccctat atgagctgcc atagagccta atatgcttaa taatccttga ggcgtaattg
     1801 aatataattc atcagccata aaacagttat caattatgcg ataaatcaag tagctcatcg
     1861 gccgaccagc ttcatcgaag taaacagcaa tctctcgatg atgataataa tcatctaatc
     1921 tattccacca ccaagcttct ctgatgatcg tatttctttc atcgtcagta tgcaactgac
     1981 gttcatataa ttgaatcaca ccattttgaa caatcaaatc attccatttt ccacgaatta
     2041 tcttaccttt gcgtggtaat ctgaaagaag caagtgcagc ccccgaaaag cgatattctt
     2101 tttggtaaat gctattgcta aaaccataat gacgataaaa tttttctgaa aatggagcta
     2161 gatttgcaac tgggattttt tgatcatgca aatcaaaaag aatttctttc attaatttag
     2221 atatatgtcc acgtcctctg tattcaggat atgatgccac ataaccaata cctgccagtg
     2281 gaacatgatg accaaatatc tcagctttaa acttattgac catcatataa ctggtcaatt
     2341 tttcttgatc aaaatatcca tatccatcac tatgatcata tcgggtcata aagttactat
     2401 ctgtagtcaa atcagaatct tttaaaaaag catattcaat caatgaagca atttgtttta
     2461 aattgtcttg gtttttcttt aatttcatag ttttccttac aatatatatt cataacttta
     2521 cttatatttt agaacatttt atgtattttt cgttagcttt tttaagattt aaatgaaaaa
     2581 gcgggatgat tagcctccca tcccgtttta attatttaca tacttcgcat ataaactaga
     2641 aatgtatctt tgcatctctt ctactgagtg tcgccgtgat cgagcacact ctttagcagg
     2701 gcgattgcat aaatagcagc ggcgactaga gtattcaagc tcttggcgtg aaagtgcagt
     2761 tttcccttta attaatacat cggcatcaaa taatcgtcct attttattat tttcttcaaa
     2821 taaaattgta gataatttaa ctactttgct agattctcgc aaaacataga aattttcaca
     2881 tccagcatca ttatttaatg cttttactaa tttataatca tatcccttat tctgccatat
     2941 ttcttctaat tgtttaattc cgtaatcaaa taatttgatt aaatatcgat tatttttaat
     3001 tggccccggg atatttaagt ttatatcaac caaagtcgca tcaggatact ttttaaaaat
     3061 agcttgctgc aaagctacac gataatcttt tccagctaat acctgagcaa tattttgcag
     3121 atttccttct tgaaaaatgt tcatttatat ctcaccgcag ttaattataa acaattgtac
     3181 ctactccatc atcaagttta cttgcatttc ttaaagaagt aataattgca gtctttcctg
     3241 ttttctctac gaaatcaatg acagcttcaa tttttggctt catgctgcct gcggcaaatt
     3301 ggccagcttc tagatacttc tttaattgat caatctttat ttttccaata ggagcttgat
     3361 caggttgatt atagttcacg taggcattgt caacagtagt tagaataact aattcatctg
     3421 cttgaatatc ttcagctagt tttgcggcac tgaagtcttt atcaattact cctgctacgc
     3481 cctgcaaact atcgtctttc actacgacag gaattccacc acctccggca gcaataggaa
     3541 caaacttgct ctttagtaaa gtgtcaatga ctggtgcatt aataatttta acgggctttg
     3601 gagaagaaac tacttgacga tagcctcgac ctgcatcttg cttataagta tattcaggat
     3661 gatagatttt ttacctctgc atttcgttaa atgtataaaa tgggccaatt ggtttagttg
     3721 gattcttaaa agttggatca ttcgcattaa ctattatctg agtaattaaa gcaacagctt
     3781 gatgtggata atttgtatgt ttaaattgat cgtctaagac cttttgcatc caatagccga
     3841 tactgccttg agtcattgct actactgtat caagcggcat agcgggatta tctttacttg
     3901 aacctttgta ttgttgcaaa agcaaattac caacctgcgg gccattacca tgaacaatcg
     3961 ctacctgatc accattttca atcattttag caacaacctt cattgtcttt ttaacctgct
     4021 tttcttgggc agctgcacta ttatcacctg cttcaatagc attgccaccc aaagctacaa
     4081 ctattctttt catctttatt tacttccttc atcaactgac ggaataaaca aattgcccaa
     4141 agtagcggcc attattgctt tgatagaatg caatctattt tccgcttcag taaattgcca
     4201 agcgtattga gagttaaaga cttcatctgt aacttccact tcacttagac catatttttc
     4261 ataaatttct ttgccaactt tagtagtgcg atcatgaaac gcaggcaaac agtgcataaa
     4321 gattagttga tcatccgggg tgcctgtcat atacatcatc ttcattgtaa ccgtgtaagg
     4381 ctttaacaat ttgattctct cactccagtc attttcaccc attgataccc agacatcagt
     4441 ataaataata tttgcacctt taacgccttg ttcaatgtca tcagtaatca aatttcttga
     4501 tccagaatct ttggcaaaac cttctgcaat tttttgtaca tcagggtgag tgaataaagg
     4561 ctttggcgta actatgtgta cattaactcc aagcatgctg ccagccacta aaagactgtc
     4621 ggcaacatta tcacgtccat cgcctacata agctaaagta agtcccttta aatgtccaaa
     4681 cttttcttta atagtcataa agtcagccaa catttggatc ggatgccatt tatctgttaa
     4741 accattccaa acagggacac cagaatattt agccaaatct tctacatctt tttgagcaaa
     4801 accgcgatat tcaatgccat caaacatact gcccaaaacc tttgcagtat cttcaatact
     4861 ttccttttta cctaaatgaa tttcaccagc acccatatat tcaggatttg cgcctaaatc
     4921 attgcatgca actacaaagg ctgaacgtgt tcttgttgaa gatttttcaa ataaaagagc
     4981 tatattcttt ccttttaaat attcatgcgg aatattttct ttagttcctt caaatgaagt
     5041 gcgaaatcaa ttagatagtt aagctccgct ggagtatagt ctttgcattt taataaactt
     5101 ctgccttgaa acacattttg taaatatttc attttgacgc ctcttacaaa tcttcacgaa
     5161 caagtggaca tgacatacat cttggacctc cacggccacg agaaagctca cttgaatgaa
     5221 tttcatgaac taaaatgcca tgctttctta acaaatcatt tgatacataa ttacgatcat
     5281 atgtaacgac ttcacctggc gcaatagcca aagtattcga gccatcattc cactgctctc
     5341 ttggggctgc aattgcatcc ccacctccgg ttggaattag gtcaatctcc gataagtgca
     5401 aataattctt taacactttg atcaaatcag tttctggggt aattttaatc tcaccatgat
     5461 catcttgctc taaaacataa atatcaatct ttcctgattt gtctaaaata aaaggatgaa
     5521 cggtacactg atcataatta atcattgtaa agactgtatc cagatgcatc atggcatgat
     5581 tatgtggtat tttaattgct aaaattgtgt cataactaga atgaccaaac aggctatgag
     5641 caaggtcagt gattgcggca gcggaagttc tttgagaaat accgattgct aaaaacatga
     5701 ttgtttaaaa tcagctcatc gccaccttct aaacgtccat gagtgtaacg atcacgccaa
     5761 ataggaatat tggcattttt aaagtcggga tgatgcttta aaacggtttc cataaataat
     5821 gactcacgtc ttctagctct aaacgtcatt ctattaatag tcatgctctt tttgagctat
     5881 ttttaaatat ggaatatcgt caattaacat tcgatttaag atatccggtg aaagattttc
     5941 taattctctt cccggtcgat gcagcataac tgtttctaat ttgccaattt cggaataaac
     6001 atgaattaag tcagtcatta tagcgcctcc taattcaaat tatgtattcg cttacaataa
     6061 ttatggatca attaggtaga agttacaatc ttaacggctt agtgaatcta ttattctttt
     6121 cattaaaggc gtcacctttt gatccttgcg ccacactaat tgcaaatgcg taatccaatt
     6181 actatgttta ataggaataa gatcatcagg tacatacgta gaagcaatag attcaggaac
     6241 aagagcaatc cccatttttc tcttcgccca agtaatcgct gttctagaat catcacattt
     6301 aacagcataa aacggcttaa tcccatgatg agcaaaagtc tggttaaaaa tttcttcaaa
     6361 tcttcgataa ataatgaggg gctgctcatt tagatcttta atccttaatt ccgtcttatc
     6421 cttaaatttg ggatcaacag taactgccat cattctttca gtagttaaag tttttgcatt
     6481 taagccatta cgattataag gcgtacgcac aattcctaaa tcgattgtct tcttttccaa
     6541 tttatcgata atgccaaagg tattatcttc ataaatatca aagttgattt ccggataaaa
     6601 cttagttaaa tcttgaaaac ttttcatagg aattagtcca gttgatgatg aagccatgcc
     6661 tattgcaatc gtgcctagtt cacctgaaac agttttatga acctgatttt tcacgctttc
     6721 tgataaagag agaatttcac tagcatagct ctgcaaaatt tgtccagcat ctgttaattc
     6781 aattccatga gcagtacgct taaataattg tgctcctagt tctatttcta gttgctttaa
     6841 ttgataactc agcggcggtt gtgcaatgta tagtctttta gctgctgaag tgatttgctt
     6901 ttcttcagct actactaaaa agtagcgtaa ttgtttaata ttcattaata atctatcctt
     6961 tttattttag ttgtatctct tattaaaaat ttctatatct tatattttaa tttagtattt
     7021 tcattcaaac aacatatgtg ctactttatt aaggtagatt tggagggaat aaaatgtctg
     7081 aaaaatttca tggcttaact caagccgaag cagataagag acttaaagaa aatgggttaa
     7141 acgaagtacc tgaacccgaa tacaactttt ttaaggaatt tctatcaaaa ttatggaatc
     7201 tttctgcctg gattctagaa ggtgccttaa tcctcgaatg tatcttaggc aaatggattc
     7261 aatctttgtt cgtcttgttg atgcttcttt ttgcggcttt taacggtgca tccaagaaga
     7321 aacagtcacg gcgggtatta aataccattt cacataagct aacccctaag gtagctgtag
     7381 aacgcgatgg taagtggatc aaaattgact ctaagcaatt agttagaggc gacttaatct
     7441 cacttcaacg tggagatgta cttgcagccg atgtaaaaat ggttagcggt aagatcgcct
     7501 gtgatgaaag ctcaattacc ggtgaatcca agcccgttaa aaagaacatt gatgacacag
     7561 cttatgctgg tactactgtt gttgaaggcg atggattagc aattgttact gcaactggta
     7621 aagattcaag aagtggtaag accattaact tgatcaacaa ttcagctgca cctggtcact
     7681 tgcaacaact tttaactaag attatttact acctttgcct acttgacggt gtacttacct
     7741 tagttattat cattgcttca ttctttaagg gtggtaattt tgatacgttt atcaacatgt
     7801 tgccattctt agccatgatg ttcatcgctt caattccggt tgcgatgccg tcaaccttta
     7861 cattgtccaa ttcatttgaa gcaacccgtt taagtaaaga aggcgtctta acagctgatt
     7921 taactggtat ccaagatgca gctaacttaa acttgctttt acttgataag acgggaacaa
     7981 tcactgaaaa caaaactgca gttgctagtt ggagcgattt aagcgatttg ccagataaag
     8041 atgtacttgc tttagccggt agtgcaactg ataagcgcaa tgcaggtatc attgatatcg
     8101 ccattgatga atacttaaaa gaaaacaata tccctgtcat ggacgttgaa cactttaccc
     8161 catttacttc tgacattggc tattctatgg ctgaagtaga tggtcacaat gttaagttag
     8221 gttcatttaa gcaactttca ttaatcgata agaatgcaaa tgaagcagtt gaaggcatca
     8281 attttaaagc tggacgctca gttgccgtgt taattgatga caaacttgcg ggagtattta
     8341 tcttacaaga taaagtaaga aaggactcta aggctgcttt agcagaactt aaaaaacggg
     8401 gcgtacgtcc aatcatgtta actggtgata atcaaagaac tgccgcagca gtcgctgaac
     8461 aagttgattt aactggtaac gttatctcta ttcatgactt tgatgaaagc accgatattg
     8521 atgaattagc agggattgcc gatgttttac ctgaagataa acttaagatg gttaaattct
     8581 tccaagaaaa aggttatatc gttggtatga ctggtgatgg tgttaacgac tctcctgctt
     8641 taaagcaagc tgaagttggt attgctgttt ctaacgctgc cgatgttgcc aagcgttcaa
     8701 gtaagatggt gcttctagat gatggcttaa gctctattat taaaattctt gatgctggtc
     8761 accgtgtata tcaacgaatg actacttggt cacttactaa gctcgccaga accgccgaat
     8821 taaatatgct tttaaccttc ggctatctct tcttcaacta tattccaatg gcattaaatg
     8881 ctatggttat ttacacaatc atgaataaca tggttaccat gatgattggt accgaccgta
     8941 cccatattac ttacaaacca gaaaattgga atatggcaag gttagccaaa atcgcattct
     9001 ctcttgctgc aggttggaca gttatcggta tcgcttttgt cagctacctc aacatgcatg
     9061 gctggagtca caattctatc tctaccatgg tctatgttta cttagttcta agtgcaatgt
     9121 taattgtatt aattactaga actcgtaaat acttctggca agattaccca tctaaacttg
     9181 taggtattgt tcaaattgcc gatgtcgcat taacctttat tttagcttta tgcggtttag
     9241 caatggctca aattagttgg caaaacttat taattaccgt tgtggttgca ttaattgcag
     9301 caattattat tgatttgatt tatcaaccag taatgaaaaa cagataatta acttaaaaca
     9361 aaaacactct gaaaactaca ttactacaat gtagttttca gagtgttttt ttgattaatg
     9421 attagtaact gtagtcaagg cattcaaagc cttaacatat tcaccatcag caattttgat
     9481 aaatggtttt tcattaattt ctttatggcc taaatagtta accttagcac cacgctttaa
     9541 aaatttgcct gggatttttt caccattctc atcataaaca aaggaatgct ttttgattct
     9601 attaactact tttacagtag acttcatata tggcaagaag gcttcttcct taacaaatct
     9661 atttttacga atctttacat aagtattacc attaattact tttatggcac gtactttgta
     9721 aagctttccc tttcttaaat gtccaacttt aacaccatgt ctattataaa cagtagcatt
     9781 tctagttaga tttaatctct taccttgtct aactggatta gtaacagctg catcaacgct
     9841 ttgtgtagtt gctgcgccta atccaataac tgctaacatt atacctgcag cagaaataat
     9901 ttgttttctc atcataatcc acccccgtag tgtttatacc attctccatc ccttatttta
     9961 tcaaaaatta tcgaattgga agcatttttt actcatctgt tttataacta tttgcttaat
    10021 tctgctaaaa ttatttataa cactacttac aagggagtaa ttattcatga ttttaacttg
    10081 ggatataatc cgtaggacta tcgaagtctt atggattatc aatattgcgt ttgctatatg
    10141 gacggtcttt agaagtcgcc gcagcgttgt tgcaacttgg gcatggatgc ttgtattaac
    10201 cgttctgccc ggtatcggtt ttatcctata tcttttcttt ggtcgtcagc tttcacatga
    10261 tgaaatcttt gctattcaag aagagcaaaa aaaggtacaa agacattatt tagctgagca
    10321 acgcgacatg cttaaagagc acgatcttct acctgaaaaa gagcgtcttc cacgagtaag
    10381 aatgctttcg gaactaaatc ttaacaacga tgatgcgatt ttaacttttg ataatcaggt
    10441 caaagtattt atttctggac cagaactttt tgaccaaatg attactgata tcaaaaatgc
    10501 caaaaaatct gtcagcttag aattttatac tttttattct aaccaattag ggcatcgtgt
    10561 tttaaaagcc ttggaagagg ctgcagctaa tggtgctaag gtaagagtaa tttatgatgc
    10621 ctctggatca agaggcacta aggcaagctt ttttgaccat ttaagagaat tgggcggcga
    10681 agctcagcca tttatttcca cttcaaaaaa gcactggttt actaccccac gactcaatta
    10741 ccacttacat agaaaattag ttattattga ccaccatatt ggctatattg gcggatttaa
    10801 tattggagat caatatgtca ataaatcacc aaaattcggt cattggcggg atacccattt
    10861 acgtgtaatt gggcaatcac caattctaat ggaggtccgg tttgcaatgg actggaacac
    10921 gtcaatcaga agaacaaatt tacctaaatt tgaattaaag gaacttaaac catttactgt
    10981 caatcgaaaa gatatcaatg ataataaaaa tgtcgctatg caaattgttt cctcaggacc
    11041 tgataatcaa cattacggca tcagacgagg ctatgaggga attattgcag gagctaaaaa
    11101 atacatttat attcaaacgc cttatttaat tcccgaagaa tcaattcttg aagccttaat
    11161 tatcgctgct aacagcggta ttgatgttcg aattatggtt ccttgcatgc ccgatcatcc
    11221 atttgtttat cgtgctacag aatactatgc taagtattta gtagcccatg gcgttaaagt
    11281 atacaaatat aatgatggtt ttattcatgc aaaaactatg gttagcggtt ctaatatttc
    11341 ttcagttggt tccgccaatc aagatttccg aagctataca ttaaactttg aggtaaactc
    11401 attcaactac aaccctgctt taactcaaga attaaagaaa atttttgaga aggacttaga
    11461 taaatgtacc cttttaacta atgactactt tgctcaacaa tcatcatggt taaaatttaa
    11521 gcaatacttc tcaagattat tatcacctat tttttaatga aaagccctct atcggtctat
    11581 ccgatggggg ttttactttg tattttaaaa atgcagtttt atttctttac ttatttttat
    11641 aagttatata ataatgataa ctattaaaaa gtaaggagga taaaacttgg ctaatagagt
    11701 aaaaataggc gttttgaatt taatgcacga taagttagat actcaacaaa gatttgcacg
    11761 cgttttgcca gatgcagacc tgactttctt ttatccacgt atgcattatc aaaatcgtcc
    11821 tgtcccacct gaagttgcaa aaacttccca gccattagat cttaatcaaa tcaaagagtt
    11881 tgatggcttt atcattacgg gcgcaccttt agatcatctt gattttgatc aagttaccta
    11941 catcgaggaa gtccgatgtt tgctccaact attagataaa tacaagttgc agcaattata
    12001 tttttgctgg ggtgcaatgg ccgctttaga ttatttttac aatattcaaa aaagaatttt
    12061 atcgaaaaaa atctttggtg tttttcctca tttaattatc gaaccacatc ctttattaaa
    12121 tggactcagc caaggattta tcgctccaca tgctcgttac gctgaaatgg ataaaacaca
    12181 gattatgcaa gatccacgat taaccattaa ttcagttgac gataatgggc atctatttat
    12241 ggtctcttct ttagaaaagc ctgagcaaaa ttttattttc tctcatatcg aatatggccg
    12301 aaaaggcctt aaaaaagaat atgaaagaga gattgctgca catccagagc gacattataa
    12361 gaagccagaa aattattcat tatcaaatct attgtttcaa tggaaagata ctcagaaaac
    12421 atttttcaat aactggctaa ctcaagttaa aaaaagcaaa ttagtattat tagataaata
    12481 aaacgaggta tacattatgt ctacaattta taattcagtt acagaactta tcggcaacac
    12541 tccattactt aagttgaatc gcgttgtacc tgacgacgcg gcagatgtct atgtaaagtt
    12601 ggaatttgaa aacccagctg gttcaattaa agacagaatt gctttagcta tgatcgaaaa
    12661 agctgaacgt gaaggcaact taaagccagg tggcacaatt gtagaaccta cttcaggcaa
    12721 taccggtatc ggtttagcca tggttgctgc agctaagggc tatcacatta ttattgttat
    12781 gccagaaact atgagcgttg agcgtcgtaa attaatgaag ggctatggtg ctgaacttat
    12841 tttgacacca ggtgcagacg gtatgaaggg ttcaattgct aaggccgaag aattagttaa
    12901 agaaaaaggc tacttcatgc caatgcaatt tgaaaataca gaaaatccta atattcatga
    12961 attaactact ggtccagaaa ttattgccgc aatgaatggt atcggcaaat ccgttgatgc
    13021 ctttgttgct ggtgttggta ctggtggtac tttatcagga attggacatg cacttaggcg
    13081 tgaaaatcca tccactaaga tatttgcact tgagccaact gaatctccac tcttaaaaga
    13141 tggaaaaaca ggtaaacatg gtatccaagg tattgccgca ggtttcatcc ctaagaattt
    13201 agataaggat atctacgatg atataattac agtttctact gatgaagcaa tggctacagc
    13261 tcgtgaagta gctaaaaacg aaggcttctt acctggtatt tcagctggtg caaacatcca
    13321 tggtgcaatc gaaattgcta aaaagttagg caagggacat gctgtggtta ctgtagttcc
    13381 agacggcggt catcgttacc tttcaactgc attatttaat gcttaaaact taatttctgt
    13441 aaacaaatac tcctaagtaa aatttcctta ggagtattat ttttatttct gttgattgtg
    13501 caccagtcaa tgctggtaca acacttttag tataatgacc tttactaatt agatcaatat
    13561 tgaatttatt taagcaccat gatattgcac taagctgtaa atatcaacat caggcaactt
    13621 ttctctaccc tttaaatcag gcaattcaat gtaaaatgca gcacctacaa gcttaccacc
    13681 aagattttca attaattcct tagaagctct taaagtacct gcagtagcca ttaaatcgtc
    13741 acagagaaca actctttggc caggcttaat tgcatcttta tgcatttcaa ggctatttga
    13801 accgtattcc aagtcatatg aagcacgttc aacttctctt ggcaacttat gtggctttct
    13861 tgctggaaca aaacctaagc ctaactcagt tgcaacagga cagcctacaa taaagccacg
    13921 tgcttcagga cctacgatta catctgcctt tctactcttt gcatattctg ccaattcatg
    13981 agtagcagca cgatacaatt caccatcttg caaaataggt gtaatatcgc gaaagacaat
    14041 tcccttatta ggaaagtcct taacacttgc aatatattta ctaaaatcaa tcgccataag
    14101 aagaaaaacc tccataattc tgtgcgtttg tattcaaaca cttttgactt gtatatttta
    14161 ccaaagattt gttataaaag tactgaaatc ttgatattta tctatctttt taccaaatta
    14221 ttaacatatg taattaattt ttgagtaggc atcgttctta gttgattaat aaatttaatt
    14281 tgtgaactcg ttgccattaa atatttagaa gctgtcaatg gttgcttctt tggattagac
    14341 tcaccaacta atttttgatc gtctaattta acaaaaccta attcaaagaa tactcgcaaa
    14401 ataaacaata cactatcata atccaaacct agatatggtg ctacagtgcg atagtcttca
    14461 ggctttaatg ctggatgggc ataaatatac tttaacactt ttccgaaata actctttgct
    14521 ggaatttgtt caacaggtaa ctgatctaat aaaaagcgta aataaatttg ttgataatct
    14581 ttttctaaag ctgcatttaa ttccacttga ttgcgaggca catcaagcaa agctactgtt
    14641 tcacccgatt gatcataatc tttaaccaag ctaattttat catcatcaat ttgaaggcga
    14701 ttcttaacaa ttggaatatt ctttttgtca aaaagcaaat aacgatctgc aaggcccatg
    14761 acaaatttct cttgtcttaa atcaattact gatgttggca cagctaattt tggggatgca
    14821 aaggctattc cttccatgat gccttgcaaa gatacttgtt tgcgataagt attcaaagag
    14881 agagtaacaa agatttttga aataaatggt aacaaattat tattcaaata atccttatta
    14941 aatcccacaa ttgctaaatt gccgtctttt ttattagctg ttaatttaac atgattctta
    15001 tcttttccta ttttgaaaaa gtgtgtaata gttggatccg aaatactaaa aattggctgc
    15061 ggatcaccag taccaaatgg tcccacttga ttaatttgag ccaaagtttg aggtgataag
    15121 tcatgcatag gcaattccat atcgtactct ttagtctcta aaccaccgtc aacatgaaaa
    15181 tcggcttcaa actttttccg taggtcattt actttatctt cttccatgga taaaccacaa
    15241 gcaaaatcat gacctccaaa tttggtcaat agactttctt ttaacggatt aagagcatca
    15301 aataagttaa aaccaatgaa tgaacgacct gatcccttaa tctccccttc atcgttttta
    15361 gttaaaacaa ttgttggttt atgcaatttt tccactatct tgttagcaac aagccccaaa
    15421 actccttcat gaaaatcagg atcatataaa actaaagtat tttgcttttg ccaactattt
    15481 tcacgaacta attccatgca gcgatcgtaa acctcagtag ttagctcttt acgcttatta
    15541 tttaagtctt caatctgatc tgcgatcttc tgtgcctcaa gatcatcatc actaagcaaa
    15601 agctctactg ccagattagc attagccaaa cgtccaacag cattaagtct aggagcaata
    15661 ttaaagccta catctgtctc attgatcgtt tctagcgtta aaccggcatt tttgataagc
    15721 gctcttaagc ccggtcgttc ggtttgatta agaacatcta acccacgttt tacaataata
    15781 tggccttcac cagtaacttt aaccatgtca ccaatagtac cgatcattgc taaatctagc
    15841 aattctggta caggatcctg cataagctca cgacaaatcg tataagctac acctgcacca
    15901 caataatcat caaaaggata ttcttgacca ggataattac agtgaacaat tgcataagca
    15961 tctggcttat tttcttgaaa agtatggtga tccgtaataa tagtatcaac gccatgtt
//
