LOCUS       c00047_gnlPro..        13317 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ELHEFKHK_118.
ACCESSION   c00047_gnlPro..
VERSION     c00047_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 10:28:23
            Original ID  :: gnl|Prokka|ELHEFKHK_118
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13317
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13317
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7350:10572]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7351..10572
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..13317
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13317
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(164..1390)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_1"
                     /sec_met_domain="PLDc_2 (E-value: 4.6e-27, bitscore: 84.7,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKEHDLLPEKERLPRVRMLSELNLNNDDAILTFDNQVKVFISGP
                     ELFDQMITDIKNAKKSVSLEFYTFYSNQLGHRVLKALEEAAANGAKVRVIYDTSGSRGT
                     KPSFFDHLRELGGEAQPFISTSKKHWFTTPRLNYHLHRKLVIIDHHIGYIGGFNIGDQY
                     VNKSPKFGHWRDTHLRVIGQSPILMEVRFAMDWNTSIRRTNLPKFELKELKPFTVNRKD
                     INDNKNVAMQLFPQDLIINITASDEAEGIIAGAKKYIYIQTPYLIPEESILEALIIAAN
                     SGIDVRIMVPCMPDHPFVYRATEYYAKYLVAHGVKVYKYNDGFIHAKTMVSGSNISSVG
                     SANQDFRSYTLNFEVNSFNYNPALTQELKKIFEKALDKCTLLTNDYFAQQSLWLKFKQY
                     FSRLLSPIF"
     CDS             complement(1405..1650)
                     /locus_tag="ctg47_2"
                     /transl_table=11
                     /translation="MILTWNIIRRTIEVLWIINIAFAVWTVFRSRRSVVATWAWMLVLT
                     VLPGIGFILYLFFGRQLSHDEIFAIQEEQKRYKDII"
     CDS             1792..2289
                     /locus_tag="ctg47_3"
                     /transl_table=11
                     /translation="MRKQIISAAGIMLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTRN
                     ATVYNRHGVKVGHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVVN
                     RIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTVT
                     NY"
     CDS             3143..3949
                     /locus_tag="ctg47_4"
                     /transl_table=11
                     /translation="MKNGQLKPGYNIQAATTDQYVVGFALYPNPTDFKTLEPFLKQMPI
                     LDKFDKIVADAGYGSEYNYSMLEKEYPDKKYYIPYTMYEKEKTRKYRNDPTKLANWFYD
                     EKDDYYLDQNGVRFNFKYYSQRKDRSTGQVRDFKVYEADEFQLTPELERLAKTKSGRQR
                     QVRYNPNWQYLKEKAKEVLQSPEGRHIYSMRKYDVEPFFGHLKNVFGTRRTHLRGKKKV
                     ETDVGIAFMMMNLSKYWNRRWSKDQFSLFKNKNREKKTTNQTQIKS"
     CDS             complement(4021..6294)
                     /locus_tag="ctg47_5"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEAPEPEYNFFKEFLSKLWNLSA
                     WVLEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRWVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVESDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSDLSDLPDKDVLALAGSATDKRNAGII
                     DIAIDEYLKENNIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYFFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFFSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             6423..7277
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     73.6; E-value: 3.1e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg47_6"
                     /sec_met_domain="LysR_substrate (E-value: 4.4e-31,
                     bitscore: 98.0, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 8.6e-24, bitscore: 73.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAEEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKLKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKHSNWITHLQLVWRKDQKVTPLMKRIIDS
                     LSR"
     CDS             7351..7536
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_7"
                     /sec_met_domain="Amidinotransf (E-value: 1.4e-11, bitscore:
                     34.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEK"
     CDS             7668..8087
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_8"
                     /sec_met_domain="Amidinotransf (E-value: 3.7e-25, bitscore:
                     78.8, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLIAMPVNEMVKQIIAGIRKNEIQNATPSLADLAEDPDYSFYS
                     FYLDPMLNVYFTRDQQAVIGNGMTINRMTSRARRRESLFMETVLKHHPDFKNANIPIWR
                     DRYTHGRLEGGDELILNNHVFSNRYFSNNFRCRNH"
     CDS             8035..8589
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_9"
                     /sec_met_domain="Amidinotransf (E-value: 5.4e-49, bitscore:
                     157.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLAIGIFQITSAAAITDLAHSLFGHSSYDTILAIKIPHNHAMMH
                     LDTVFTMINYDQCTVHPFILDKSGKIDIYVLEQDDHGEIKITPETDLIKVLKNYLHLSE
                     IDLIPTGGGDAIAAPREQWNNGSNTLAIAPGEVVTYDRNYVSNDLLRKHGILVHEIHSS
                     ELSRGRGGPRCMSCPLVREDL"
     CDS             8601..8738
                     /locus_tag="ctg47_10"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSLLKCKDYTPTELNYLIDFALHLKELKKIFRMNI
                     "
     CDS             8837..9445
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_11"
                     /sec_met_domain="OTCace (E-value: 4.3e-37, bitscore: 117.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 9.8e-25, bitscore:
                     77.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDDIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPTQMLADFMTIKEKFGHLKVLILAYVGDGRDNVADSLLVAGSMLGV
                     NVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIEQGVKGANIIYTDVWVSMGEND
                     WSERIKLLKPYTVTMNMMYMTGTPDDQLIFMHCLPAFHD"
     CDS             9640..10062
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_12"
                     /sec_met_domain="AA_kinase (E-value: 5.6e-13, bitscore:
                     39.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVALGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNLAMPLDTVVSMTQGSIGYWMQKALDDQFKHTNYPH
                     QAVALITQIIVNANDPTFKNPTKPIGPFYTFNEMQR"
     CDS             10231..10572
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_13"
                     /sec_met_domain="AA_kinase (E-value: 2.4e-19, bitscore:
                     60.0, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGVAGVIDKDFSAAKLAEDIQADELVILTTVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDFVEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             10589..11125
                     /locus_tag="ctg47_14"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNKGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             11246..12412
                     /locus_tag="ctg47_15"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIEYAFLKDSDLTTDSNFMPRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEIIFDLHDQK
                     IPVANLAPFSEKFYRHYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHIDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMAAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLSCMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             12428..12589
                     /locus_tag="ctg47_16"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLNVVVSGINVVISLLIMFNKYQIRKDKKQISDE
                     GHAPLDEN"
     CDS             12592..13197
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_17"
                     /sec_met_domain="LysR_substrate (E-value: 7.1e-19,
                     bitscore: 58.1, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLANGQQMWQKIAAFYTNEDVVIKDFILLAKKVY"
ORIGIN
        1 ttctattgaa tactacaact tgagtctagt tcgattggac ttttttatta actaaaatga
       61 tttaactagc accacgcgta taaaaaataa gtaaagaaat agaactgcat ttttaaaata
      121 caaagtaaaa cccctatcgg ataaaccgat agagggcttt tcattaaaaa ataggtgata
      181 ataatcttga gaagtattgc ttaaatttta accataatga ttgttgagca aagtagtcat
      241 tagttaaaag ggtacattta tctaaggcct tctcaaaaat tttctttaat tcttgagtta
      301 aagcagggtt gtagttgaat gagtttacct caaagtttaa tgtatagctt cggaaatctt
      361 gattggcgga accaactgaa gaaatattag aaccgctaac catagttttt gcatgaataa
      421 aaccatcatt atatttgtat actttaacgc catgggctac taaatactta gcatagtatt
      481 ctgtagcacg ataaacaaat ggatgatcgg gcatgcaagg aaccataatt cgaacatcaa
      541 taccgctgtt agcagcgata attaaggctt caagaattga ttcttcggga attaaataag
      601 gcgtttgaat ataaatgtat tttttagctc ctgcaataat tccctcagcc tcgtctgatg
      661 ccgtaatgtt gattatcagg tcctgaggaa acaattgcat agcgacattt ttattatcat
      721 tgatatcttt tcgattgaca gtaaatggtt taagttcctt taattcaaat ttaggtaaat
      781 ttgttcttct gattgacgtg ttccagtcca ttgcaaaccg gacctccatt agaattggtg
      841 attgcccaat tacacgtaaa tgggtatccc gccaatgacc gaattttggt gatttattga
      901 catattgatc tccaatatta aatccgccaa tatagccaat atggtggtca ataataacta
      961 attttctatg taagtggtaa ttgagtcgtg gggtagtaaa ccagtgcttt tttgaagtgg
     1021 aaataaatgg ctgagcttcg ccccccaatt ctcttaaatg gtcaaaaaag cttggcttag
     1081 tgcctcttga tccagaggta tcataaatta ctcttacctt agcaccatta gctgcagcct
     1141 cttccaaggc ttttaaaaca cgatgcccta attggttaga ataaaaagta taaaattcta
     1201 agctgacaga ttttttggca tttttgatat cagtaatcat ttggtcaaaa agttctggtc
     1261 cagaaataaa tactttgacc tgattatcaa aagttaaaat cgcatcatcg ttgttaagat
     1321 ttagttccga aagcattctt actcgtggaa gacgctcttt ttcaggtaga agatcgtgct
     1381 ctttaagcat gtcgcgttgc tcagctaaat aatgtctttg tacctttttt gctcttcttg
     1441 aatagcaaag atttcatcat gtgaaagctg acgaccaaag aaaagatata ggataaaacc
     1501 gataccgggc agaacggtta atacaagcat ccatgcccaa gttgcaacaa cgctgcggcg
     1561 acttctaaag accgtccata cagcaaacgc aatattgata atccataaga cttcgatagt
     1621 cctacggatt atattccaag ttaaaatcat gaattaagta gtgttataaa taattttagc
     1681 agaattaagc aaatagttat aaaacagatg agtaaaaaat gcttccaatt cgataatttt
     1741 tgataaaata agggatggag aatagtataa acactacggg ggtggattat gatgagaaaa
     1801 caaattattt ctgctgcagg tataatgtta gcagttattg gattaggcgc agcaactaca
     1861 caaagcgttg atgcagttgt tactaatcca gttagacaag gtaagagatt aaatctaact
     1921 agaaatgcta ctgtttataa tagacatggt gttaaagttg gacatttaag aaagggaaag
     1981 ctttacaaag tacgtgccat aaaagtaatt aatggtaata cttatgtaaa gattcgtaaa
     2041 aatagatttg ttaaggaaga agccttcttg ccatatatga agactactgt aaaagtagtt
     2101 aatagaatca aaaagcattc ctttgtttat gatgagaatg gtgaaaaaat cccaggcaaa
     2161 tttttaaagc gtggtgctaa ggttaactat ttaggccata aagaaattaa tgaaaaacca
     2221 tttatcaaaa ttgctgatgg tgaatatgtt aaggctttga atgccttgac tacagttact
     2281 aattattaat caaaaaaaca ctctgaagtg tctgggaaat aactaattct cggacatgaa
     2341 aaaagaacga tgatttccta tcggatttca tcgttctttt tctatactnn nnnnnnnnnn
     2401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2461 nncggaagat gttttgctgg gtgataccgc taaaactgga cggcctgctt atcatccagc
     2521 tatgatgctt aagattttgc tttttgcata ttccagaaga gtattttcag gcagaaagat
     2581 tgaattatgc tggaagaaaa cctgcctatg atggtattgg cagagcacca aaagatttca
     2641 tatcatacca tcaataactt taggtctnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngc
     2761 ttttgtttgg cgcaaggcag ctgaaaagtt ccatgaaaag ctcaaaggcc aagcagttga
     2821 actttatgat gaactgattg ccaaagaagt agtcaaagca atggctcaag aaaaggtaca
     2881 aaccagtcaa ggtttagaag aactagcgca agaaacagaa gatgagatat tgaaaagctg
     2941 actaaagaaa ttgagcaaga acctaaggcg attcctggcg gctcgcttag aaaagcaaga
     3001 agacgtggtc ttaaaaagct gcttcatagg ctaaaaaaag actatgttcc tcgcatgaag
     3061 aaatatgaag aagcagaaga aatctttgct ggacgcaaca gctattccaa gactgatcat
     3121 gatgcatatg aaggaagacc atatgaagaa tggtcagctg aagccaggct acaatattca
     3181 agccgctaca acggatcaat atgtagtcgg ctttgccttg taccctaacc caactgactt
     3241 taagacatta gaaccatttt taaagcagat gccaatatta gataagttcg ataagattgt
     3301 cgccgatgct ggttatggca gcgagtacaa ctattctatg ctagagaaag aatatccaga
     3361 caagaagtac tatattccct acactatgta tgaaaaggaa aagaccagaa aatatcgcaa
     3421 cgatccgact aagctggcta actggttcta tgatgaaaaa gatgattact atcttgatca
     3481 aaatggcgtc aggttcaact ttaagtatta tagtcagcgt aaagaccgct cgactggtca
     3541 ggttcgcgat tttaaggtct atgaagcaga tgaattccaa ctaacgccag aattagaacg
     3601 cctagccaaa accaaaagtg gtcgtcaacg ccaagtacgc tataatccta actggcagta
     3661 tttaaaggaa aaagccaaag aagttcttca gagtcctgaa ggcaggcaca tctacagcat
     3721 gagaaagtat gatgtggagc cattttttgg acatttgaag aacgtttttg gcacgcgtcg
     3781 aactcattta agaggcaaaa agaaggttga aactgatgtt ggcatagcct tcatgatgat
     3841 gaatttaagc aaatattgga acagaagatg gtcaaaagac caattttctt tgttcaaaaa
     3901 taaaaataga gagaaaaaaa cgaccaatca aactcaaatt aagagttgaa ttgatcgttt
     3961 ttcggtatct aagggttggt tatttcccag acacttcaga gtgtttttgt tttaagttaa
     4021 ttatctgttt ttcattactg gttgataaat caaatcaata ataattgctg caattaatgc
     4081 aaccacaacg gtaattaata agttttgcca actaatttga gccattgcta aaccgcataa
     4141 agctaaaata aaggttaatg cgacatcggc aatttgaaca atacctacaa gtttagatgg
     4201 gtaatcttgc cagaagtatt tacgagttct agtaattaat acaattaaca ttgcacttag
     4261 aactaagtaa acatagacca tggtagagat agaattgtga ctccagccat gcatgttgag
     4321 gtagctgaaa aaagcgatac cgataactgt ccaacctgca gcaagagaga atgcgatttt
     4381 ggctaacctt gccatattcc aattttctgg tttgtaagta atatgggtac ggtcggtacc
     4441 aatcatcatg gtaaccatgt tattcatgat tgtgtaaata accatagcat ttaatgccat
     4501 tggaatatag ttgaagaaga aatagccgaa ggttaaaagc atagttaatt cggcggttct
     4561 ggcgagctta gcaagtgacc aagtagtcat tcgttgatat acacggtgac cagcatcaag
     4621 aattttaaca atagagctta agccatcatc tagaagcacc atcttacttg aacgcttggc
     4681 aacatcggca gcgttagaaa cagcaatacc aacttcagct tgctttaaag caggagagtc
     4741 gttaacacca tcaccagtca taccaacgat ataacctttt tcttggaaga atttaaccat
     4801 cttaagttta tcttcaggta aaacatcggc aattcctgct aattcatcaa tatcggtgct
     4861 ttcatcaaag tcatgaatag agataacgtt accagttaaa tcaacttgtt cagcgactgc
     4921 tgcggcagtt ctttgattat caccagttaa catgattgga cgtacgcccc gttttttaag
     4981 ttctgctaaa gcagccttag agtcctttct tactttatct tgtaagataa atactcccgc
     5041 aagtttgtca tcaattaaca cggcaactga gcgtccagct ttaaaattga tgccttcaac
     5101 tgcttcattt gcattcttat cgattaatga aagttgctta aatgaaccta acttaacatt
     5161 gtgaccatct acttcagcca tagaatagcc agtgtcagaa gtaaatgggg taaagtgttc
     5221 aacgtccatg acagggatat tgttttcttt taagtattca tcaatggcga tatcaatgat
     5281 acctgcattg cgcttatcag ttgcactacc ggctaaagca agtacatctt tatctggcaa
     5341 atcgcttaaa tcgctccaac tagcaactgc agttttgttt tcagtgattg ttcccgtctt
     5401 atcaagtaaa agcaagttta agttagctgc atcttggata ccagttaaat cagctgttaa
     5461 gacgccttct ttacttaaac gggttgcttc aaatgaattg gacaatgcaa aggttgacgg
     5521 cattgcaacc ggaattgaag cgatgaacat catggctaag aatggcaaca tgttgataaa
     5581 cgtatcaaaa ttaccaccct taaagaatga agcaatgata ataactaagg taagtacacc
     5641 gtcaagtagg caaaggtagt aaataatctt agttaaaagt tgttgcaagt gaccaggtgc
     5701 agctgaattg ttgatcaagt taatggtctt accacttctt gaatctttac cagttgcagt
     5761 aacaattgct aatccatcgc tttcaacaac agtagtacca gcataagctg tgtcatcaat
     5821 gttcttttta acgggcttag attcaccggt aattgagctt tcatcacagg caatcttacc
     5881 gctaaccatt tttacatcgg ctgcaagtac atctccacgt tgaagtgaga ttaagtcgcc
     5941 tctaactaat tgcttagagt caattttgat ccacttacca tcgcgttcta cagccacctt
     6001 aggggttagc ttatgtgaaa tggtatttaa tacccaccgt gactgtttct tcttggatgc
     6061 accgttaaaa gccgcaaaaa gaagcatcaa caagacgaac aaagattgaa tccatttgcc
     6121 taagatacat tcgaggatta aggcaccttc tagaacccag gcagaaagat tccataattt
     6181 tgatagaaat tccttaaaaa agttgtattc aggttcaggt gcttcgttta acccatcttc
     6241 cttaagtctc ttatctgctt cggcttgagt taagccatga aatttttcag acattttatt
     6301 ccctccaaat ctaccttaat aaagtagcac atatgttgtt tgaatgaaaa tactaaatta
     6361 aaatataaga tatagaattt tttaataaga gatacaacta aaataaaaaa gatagattat
     6421 taatgaatat taaacaatta cgctactttt tagtagtagc cgaagaaaag caaatcactt
     6481 cagcagctaa aagactatac attgcacaac cgccgcttag ttatcaatta aagcaactag
     6541 aaatagaact aggagcacaa ttatttaagc gtactgctca cggaattgaa ttaacagatg
     6601 ctggacaaat tttgcagagc tatgctagtg aaattctctc tttatcagaa agcgtgaaaa
     6661 atcaggttca taaaactgtt tcaggtgaac taggcacgat tgcaataggc atggcttcat
     6721 catcaactgg actaattcct atgaaaagtt ttcaagattt aactaagttt tatccggaaa
     6781 tcaactttga tatttatgaa gataatacct ttggcattat cgataaattg gaaaagaaga
     6841 caatcgattt aggaattgtg cgtacgcctt ataatcgtaa tggcttaaat gcaaaaactt
     6901 taactactga aagaatgatg gcagttactg ttgatcccaa attaaaggat aagacggaat
     6961 taaggattaa agatctaaat gagcagcccc tcattattta tcgaagattt gaagaaattt
     7021 ttaaccagac ttttgctcat catgggatta agccgtttta tgctgttaaa tgtgatgatt
     7081 ctagaacagc gattacttgg gcgaagagaa aaatggggat tgctcttgtt cctgaatcta
     7141 ttgcttctac gtatgcacct gatgatctta ttcctattaa acatagtaat tggattacgc
     7201 atttgcaatt agtgtggcgc aaggatcaaa aggtgacgcc tttaatgaaa agaataatag
     7261 attcactaag ccgttaagat tgtaacttct acctaattga tccataatta ttgtaagcgg
     7321 atacataatt ttgaattagg agacgctata atgactgact taattcatgt ttattccgaa
     7381 attggcaaat tagaaacagt tatgctgcat cgaccgggaa gagaattaga aaatctttca
     7441 ccggatatct taaatcgaat gttaattgac gatattccat atttaaaaat agctcaaaaa
     7501 gagcatgact attttgccca cactttggaa aaatagggag ttcatgtcgt ttatctagaa
     7561 gatttattag ctcactattt gactaatgaa gatgtccgta caaaatttgt agatcaatta
     7621 ttagaagaat ccaatataaa aaagaagatc cattacatca attactgatg gactatttaa
     7681 tagcaatgcc agtaaatgaa atggttaagc aaataattgc tggtattaga aaaaatgaaa
     7741 tacaaaatgc aactccttca ttagccgatc tagctgaaga tccagattat tcattttatt
     7801 cattttattt ggatccaatg ctaaatgtgt attttactcg tgatcaacaa gcagttattg
     7861 gtaatggcat gactattaat agaatgacgt ctagagctag aagacgtgag tcattattta
     7921 tggaaaccgt tttaaagcat catcccgact ttaaaaatgc caatattcct atttggcgtg
     7981 atcgttacac tcatggacgt ttagagggtg gcgatgagct gattttaaac aatcatgttt
     8041 ttagcaatcg gtatttttca aataacttcc gctgccgcaa tcactgacct tgctcatagc
     8101 ctgtttggtc attctagtta tgacacaatt ttagcaatta aaataccaca taatcatgcc
     8161 atgatgcatc tggatacagt ctttacaatg attaattatg atcagtgtac cgttcatcct
     8221 tttattttag acaaatcagg aaagattgat atttatgttt tagagcaaga tgatcatggt
     8281 gagattaaaa ttaccccaga aactgatttg atcaaagtgt taaagaatta tttgcactta
     8341 tcggagattg acctaattcc aaccggaggt ggggatgcaa ttgcagcccc aagagagcag
     8401 tggaataatg gctcgaatac tttggctatt gcgccaggtg aagtcgttac atatgatcgt
     8461 aattatgtat caaatgattt gttaagaaag catggcattt tagttcatga aattcattca
     8521 agtgagcttt ctcgtggccg tggaggtcca agatgtatgt catgtccact tgttcgtgaa
     8581 gatttgtaag aggcgtcaaa atgaaatatt tacaaaatgt gtttcaaggc agaagtttat
     8641 taaaatgcaa agactatact ccaacggagc ttaactatct aattgatttt gcacttcatt
     8701 tgaaggaact aaagaaaata ttccgcatga atatttaaaa ggaaagaata tagctctttt
     8761 atttgaaaaa tcttcaacaa gaacacgttc agcctttgta gttgcatgca atgatttagg
     8821 cgcaaatcct gaatatatgg gtgctggtga aattcattta ggtaaaaagg aaagtattga
     8881 agatactgcc aaggttttgg gcagtatgtt tgatgacatt gaatatcgcg gttttgctca
     8941 aaaagatgta gaagatttgg ctaaatattc tggtgtccct gtttggaatg gtttaacaga
     9001 taaatggcat ccgacccaaa tgttggctga ctttatgact attaaagaaa agtttggaca
     9061 tttaaaggta cttattttag cttatgtagg cgatggacgt gataatgttg ccgacagtct
     9121 tttagtggct ggcagcatgc ttggagttaa tgtacacata gttacgccaa agcctttatt
     9181 cactcaccct gatgtacaaa aaattgcaga aggttttgcc aaagattctg gatcaagaaa
     9241 tttgattact gatgacattg aacaaggcgt taaaggtgca aatattattt atactgatgt
     9301 ctgggtatca atgggtgaaa atgactggag tgagagaatc aaattgttaa agccttacac
     9361 ggttacaatg aatatgatgt atatgacagg caccccggat gatcaactaa tctttatgca
     9421 ctgtttgcct gcgtttcatg attgaactgc taaagttggc aaagaaattt atgaaaaata
     9481 tggtctaagt gaagtggaag ttacagatga agtctttaac tctcaatacg cttggcaatt
     9541 tactgaagcg gaaaatagat tgcattctat caaagcaata atggccgcta ctttgggcaa
     9601 tttgtttatt ccgtcagttg atgaaggaag taaataaaga tgaaaagaat agttgtagct
     9661 ttgggtggca atgctattga agcaggtgat aatagtgcag ctgcccaaga aaagcaggtt
     9721 aaaaagacaa tgaaggttgt tgctaaaatg attgaaaatg gtgatcaggt agcgattgtt
     9781 catggtaatg gcccgcaggt tggtaatttg cttttgcaac aatacaaagg ttcaagtaaa
     9841 gataatctcg ctatgccgct tgatacagta gtatcaatga ctcaaggcag tatcggctat
     9901 tggatgcaaa aggccttaga cgatcaattt aaacatacaa attatccaca tcaagctgtt
     9961 gctttaatta ctcagataat agttaatgcg aatgatccaa cttttaagaa tccaactaaa
    10021 ccaattggcc cattttatac atttaacgaa atgcagaggt aaaaaatcta tcatcctgaa
    10081 tatacttata agcaagatac aggtcgaggc tatcgtcaag tagtttcttc tccaaagccc
    10141 gttaaaatta ttaatgcacc aggcattgac actttactaa agagcaagtt tgttcctatt
    10201 gctgccggag gtggtggaat tcctgttgta gtgaaagacg atagtttgca aggcgtagca
    10261 ggagtaattg ataaagactt cagtgccgca aaactagctg aagatattca agcagatgaa
    10321 ttagttattc taactaccgt tgacaatgcc tacgtgaact ataatcaacc tgatcaagct
    10381 cctattggaa aaataaagat tgatcaatta aagaagtatc tagaagctgg ccaatttgct
    10441 gcaggcagca tgaagccaaa aattgaagct gtcattgatt tcgtagagaa aacaggaaag
    10501 actgcaatta ttacttcttt aagaaatgca agtaaacttg atgatggagt aggtacaatt
    10561 gtttataatt aactgcggtg agatataaat gaacattttt caagaaggaa atccgcaaaa
    10621 tattgctcag gtattagctg gaaaagatta tcgtgtagct ttgcagcaag ctatttttaa
    10681 aaagtatcct gatgcgactt tggttgatat aaacttaaat atcccggggc caattaaaaa
    10741 taatcgatat ttaatcaaat tatttgatta cggaattaaa caattagaag aaatatggca
    10801 gaataaggga tatgactata aattagtaaa agcattaaat aatgatgctg gatgtgaaaa
    10861 tttctatgtt ttgcgagaat ctagcaaagt agttaaatta tctacaattt tatttgaaga
    10921 aaataataaa ataggacgat tatttgatgc cgatgtatta attaaaggga aaactgcact
    10981 ttcacgccaa gagcttgaat actctagtcg ccgctgctat ttatgcaatc gccctgctaa
    11041 agagtgtgct cgatcacggc gacactcagt agaagagatg caaagataca tttctagttt
    11101 atatgcgaag tatgtaaata attaaaacgg gatgggaggc taatcatccc gttttttcat
    11161 ttaaatctta aaaaaagcta acgaaaaata cataaaatgt tctaaaatat aagtaaagtt
    11221 atgaatatat attgtaagga aaactatgaa attaaagaaa aaccaagaca atttaaaaca
    11281 aattgcttca ttgattgaat atgctttttt aaaagattct gatttgacta cagatagtaa
    11341 ctttatgccc cgatatgatc atagtgatgg atatggatat tttgatcaag aaaaattgac
    11401 cagttatatg atggtcaata agtttaaagc tgagatattt ggtcatcatg ttccactggc
    11461 aggtattggt tatgtggcat catatcctga atacagagga cgtggacata tatctaaatt
    11521 aatgaaagaa attatttttg atttgcatga tcaaaaaatc ccagttgcaa atctagctcc
    11581 attttcagaa aaattttatc gtcattatgg ttttagcaat agtatttacc aaaaagaata
    11641 tcgcttttcg ggggctgcac ttgcttcttt cagattacca cgcaaaggta agataattcg
    11701 tggaaaatgg aatgatttga ttgttcaaaa tggtgtgatt caattatatg aacgtcagtt
    11761 gcatattgac gatgaaagaa atacgatcat cagagaagct tggtggtgga atagattaga
    11821 tgattattat catcatcgag agattgctgt ttacttcgat gaagctggtc ggccgatgag
    11881 ctacttgatt tatcgcataa ttgataactg ttttatggct gatgaattat attcaattac
    11941 gcctcaagga ttattaagca tattaggctt tatggcagct catatagggt caattaaaga
    12001 gttttgtatg acattgcctg agaagtcttt attggctgaa ctttttccag agcaaaatga
    12061 attggatatt caacttcatc catatatgat gagtagaatt attgatttcc aaaaagtctt
    12121 gtcatgcatg cgcccattgc aagagggtac ttttaacatc gaagttaatt atgatgatca
    12181 gtgtccatgg aatatcggcg tttggcaatt aactaattat gatcaccaag ttaagtgtga
    12241 acgaaaagaa gatgaactag ttgatttctc tggtccaatt acaacatgga ctcaaatctt
    12301 attaggacgt ttaactatgg aatccgcaat taaacttggt ttgatcacag attatagaat
    12361 taaaaagttg gactttgtaa aaggtaaagt ctcattttat gattattttt agaagaaggt
    12421 atccaaaatg agtaagcaaa agaaagttag attactaaaa tttttaaacg tggtagttag
    12481 tggaataaat gtggttattt cgctattgat tatgttcaac aaatatcaaa ttagaaaaga
    12541 taaaaaacaa atatcagatg aaggtcatgc cccattggat gaaaattaac tatgaaaaaa
    12601 ttgagaatag catactttaa ccaacttggt agaagacaat tagatcgaat tgtagaccaa
    12661 tttaagcaaa aacattctga tgtagaaatt gaattaattg gaatgggaca cgatgaagct
    12721 tttgataaat tagccaaaaa tgaagttgat ttagcgatta gtgatttgcg cgatgatcag
    12781 ctcgatttta agaaagaaat cttaggtcag gaagcagtaa tggctatttt gcaaaagggt
    12841 agttatccta gcggtgttca gatgatcaat aaagatgatc tagctgattt aacctgtttt
    12901 attgtagcta agcctgaaga agaggctgca gaactccatt tatttaaaga tatttatcag
    12961 attagaagcc cattcattgc ttcaaattcc gtagaagagg cagcattgtt agtagcttct
    13021 ggatcaggat attttttaat gaatgaagca accgccagtt taattagtaa tgatacttta
    13081 caacgattgt ttttattggc taatggacaa caaatgtggc aaaagattgc agctttttat
    13141 accaatgaag atgtagtaat taaagatttt attttgttag ctaaaaaagt atattaatct
    13201 atcttggaac agcaaaatac tgtaaaaata aaaatgcgct gattgtaaaa ttaaattgaa
    13261 cacttgataa aaaataaaaa gtccattcgg acctgtttga tagaatgtag ttaccac
//
