## Fri May 2 01:47:44 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_013281055.1/GCA_013281055.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_013281055.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_013281055.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs CAFIFDFH_00001 405566.lhv_1214 4.53e-113 325.0 COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes,4HDFS@91061|Bacilli,3F3TA@33958|Lactobacillaceae 91061|Bacilli H Site-specific DNA-methyltransferase (adenine-specific) dpnM - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 CAFIFDFH_00003 405566.lhv_1216 7.85e-151 423.0 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4IEJ7@91061|Bacilli,3F4SP@33958|Lactobacillaceae 91061|Bacilli L Integrase - - - - - - - - - - - - Phage_integrase CAFIFDFH_00005 326425.lhe_1109 0.0 885.0 COG1249@1|root,COG1249@2|Bacteria,1TS0Z@1239|Firmicutes,4HBYB@91061|Bacilli,3F3K2@33958|Lactobacillaceae 91061|Bacilli C Glutathione reductase gshR3 - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim CAFIFDFH_00006 326425.lhe_1110 2.62e-121 346.0 COG0454@1|root,COG0456@2|Bacteria,1V6Z8@1239|Firmicutes,4HMP7@91061|Bacilli,3F6WQ@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 CAFIFDFH_00007 1033837.WANG_1266 3.18e-76 234.0 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 CAFIFDFH_00008 1423814.HMPREF0549_0425 6.36e-49 162.0 COG1073@1|root,COG1073@2|Bacteria,1TPW7@1239|Firmicutes,4HEFQ@91061|Bacilli,3F5IC@33958|Lactobacillaceae 91061|Bacilli S Hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - AXE1,DLH,Peptidase_S15 CAFIFDFH_00009 405566.lhv_1222 2.32e-184 512.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,3F4IY@33958|Lactobacillaceae 91061|Bacilli C nitroreductase nfrA - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase CAFIFDFH_00010 326425.lhe_1113 2.32e-62 192.0 COG3830@1|root,COG3830@2|Bacteria 2|Bacteria T phosphoserine phosphatase activity - - 1.1.1.3 ko:K00003,ko:K07166 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT_6 CAFIFDFH_00011 326425.lhe_1114 4.8e-109 314.0 COG1309@1|root,COG1309@2|Bacteria,1V6JC@1239|Firmicutes,4IF0F@91061|Bacilli,3F58C@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CAFIFDFH_00012 405566.lhv_1224 6.75e-138 390.0 COG0846@1|root,COG0846@2|Bacteria,1V192@1239|Firmicutes,4IJ3S@91061|Bacilli,3F5GG@33958|Lactobacillaceae 91061|Bacilli K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - ko:K09705 - - - - ko00000 - - - - CAFIFDFH_00013 525365.HMPREF0548_1143 5.4e-121 358.0 COG0846@1|root,COG0846@2|Bacteria,1V192@1239|Firmicutes,4IJ3S@91061|Bacilli,3F5GG@33958|Lactobacillaceae 91061|Bacilli K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - - - - - - - - - - - CAFIFDFH_00014 405566.lhv_1226 1.04e-138 395.0 COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,4HAQT@91061|Bacilli,3F4Q7@33958|Lactobacillaceae 91061|Bacilli K COG COG0846 NAD-dependent protein deacetylases, SIR2 family - - - - - - - - - - - - SIR2 CAFIFDFH_00015 326425.lhe_1116 1.12e-36 130.0 COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,4HAQT@91061|Bacilli,3F4Q7@33958|Lactobacillaceae 91061|Bacilli K COG COG0846 NAD-dependent protein deacetylases, SIR2 family - - - - - - - - - - - - SIR2 CAFIFDFH_00016 326425.lhe_1117 1.3e-121 347.0 COG0454@1|root,COG0456@2|Bacteria,1V5SA@1239|Firmicutes,4ISZX@91061|Bacilli,3FBU8@33958|Lactobacillaceae 91061|Bacilli K acetyltransferase - - - - - - - - - - - - Acetyltransf_1 CAFIFDFH_00017 326425.lhe_1118 1.39e-110 317.0 COG0783@1|root,COG0783@2|Bacteria,1VCVJ@1239|Firmicutes,4HMBD@91061|Bacilli,3F5WI@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin CAFIFDFH_00018 1423748.BALB01000017_gene1505 3.26e-227 660.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,3F52K@33958|Lactobacillaceae 91061|Bacilli KL domain protein snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM CAFIFDFH_00019 1423748.BALB01000017_gene1505 2.31e-21 92.4 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,3F52K@33958|Lactobacillaceae 91061|Bacilli KL domain protein snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM CAFIFDFH_00020 405566.lhv_1231 2.5e-139 394.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,3F543@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf CAFIFDFH_00021 326425.lhe_1121 0.0 1235.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,3F430@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim CAFIFDFH_00022 405566.lhv_1233 0.0 1591.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,3F3MJ@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV CAFIFDFH_00023 326425.lhe_1123 1.47e-218 603.0 COG0583@1|root,COG0583@2|Bacteria,1UYS5@1239|Firmicutes,4HF07@91061|Bacilli,3F48B@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate CAFIFDFH_00024 326425.lhe_1124 6.05e-221 609.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,3F3PJ@33958|Lactobacillaceae 91061|Bacilli C inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 CAFIFDFH_00025 326425.lhe_1125 2.19e-142 401.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,3F3TI@33958|Lactobacillaceae 91061|Bacilli G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Hydrolase_3,Pro_isomerase CAFIFDFH_00026 326425.lhe_1126 2.23e-73 220.0 COG1396@1|root,COG1396@2|Bacteria,1UUUD@1239|Firmicutes,4I3X4@91061|Bacilli,3F8QF@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3,HTH_31 CAFIFDFH_00027 326425.lhe_1127 1.62e-30 112.0 COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,4HM4F@91061|Bacilli,3F5F5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 CAFIFDFH_00028 326425.lhe_1127 1.7e-79 239.0 COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,4HM4F@91061|Bacilli,3F5F5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 CAFIFDFH_00029 1423748.BALB01000007_gene908 8.71e-45 145.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc CAFIFDFH_00030 891391.LAC30SC_06090 8.21e-32 121.0 COG3757@1|root,COG3757@2|Bacteria,1VF8D@1239|Firmicutes,4HX0U@91061|Bacilli,3F4U9@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,LysM,SH3_5,SLAP CAFIFDFH_00031 1423748.BALB01000007_gene907 1.36e-58 191.0 COG3757@1|root,COG3757@2|Bacteria,1VF8D@1239|Firmicutes,4HX0U@91061|Bacilli,3F4U9@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,LysM,SH3_5,SLAP CAFIFDFH_00032 1423748.BALB01000007_gene907 6.85e-56 184.0 COG3757@1|root,COG3757@2|Bacteria,1VF8D@1239|Firmicutes,4HX0U@91061|Bacilli,3F4U9@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,LysM,SH3_5,SLAP CAFIFDFH_00033 1423748.BALB01000007_gene907 8.73e-34 125.0 COG3757@1|root,COG3757@2|Bacteria,1VF8D@1239|Firmicutes,4HX0U@91061|Bacilli,3F4U9@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,LysM,SH3_5,SLAP CAFIFDFH_00034 405566.lhv_2516 4.02e-71 215.0 2DINK@1|root,303QK@2|Bacteria,1TV1H@1239|Firmicutes,4HYBN@91061|Bacilli,3F7U7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00035 326425.lhe_1131 1.35e-140 397.0 29N5D@1|root,30939@2|Bacteria,1V5Q4@1239|Firmicutes,4HHUF@91061|Bacilli,3F5S8@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF5052) XK27_00160 - - - - - - - - - - - DUF5052 CAFIFDFH_00036 405566.lhv_2517 2.1e-49 160.0 COG0563@1|root,COG0563@2|Bacteria,1V7AW@1239|Firmicutes,4HH8A@91061|Bacilli,3F6PA@33958|Lactobacillaceae 91061|Bacilli F topology modulation protein flaR - - - - - - - - - - - - CAFIFDFH_00037 405566.lhv_1250 7.91e-59 184.0 29EME@1|root,301JC@2|Bacteria,1U5N3@1239|Firmicutes,4IFCU@91061|Bacilli,3F67R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00038 405566.lhv_1250 1.17e-31 113.0 29EME@1|root,301JC@2|Bacteria,1U5N3@1239|Firmicutes,4IFCU@91061|Bacilli,3F67R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00039 326425.lhe_1133 5.71e-262 717.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HANE@91061|Bacilli,3F3P9@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family xerS - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase CAFIFDFH_00040 326425.lhe_1134 1.52e-205 569.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,3F40W@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family - - - - - - - - - - - - DegV CAFIFDFH_00041 326425.lhe_1135 5.69e-86 254.0 29P8Y@1|root,30A72@2|Bacteria,1U6A0@1239|Firmicutes,4IG18@91061|Bacilli,3F7ER@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_24,MarR_2 CAFIFDFH_00042 405566.lhv_1255 0.0 1107.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,3F3PS@33958|Lactobacillaceae 91061|Bacilli K Fibronectin-binding protein FbpA - - - - - - - - - - - DUF814,FbpA CAFIFDFH_00043 326425.lhe_1137 0.0 2063.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB1 - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS CAFIFDFH_00044 326425.lhe_1138 5.87e-255 699.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,3F43R@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase CAFIFDFH_00045 405566.lhv_1258 8.92e-219 603.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,3F3P6@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 CAFIFDFH_00046 326425.lhe_1140 1.1e-102 297.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,3F66R@33958|Lactobacillaceae 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 CAFIFDFH_00047 326425.lhe_1141 0.0 1082.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,3F3U6@33958|Lactobacillaceae 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS CAFIFDFH_00048 1423748.BALB01000007_gene894 8.11e-44 144.0 29PP8@1|root,30AME@2|Bacteria,1U6UZ@1239|Firmicutes,4IGNU@91061|Bacilli,3F8IU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00049 1423748.BALB01000007_gene893 2.92e-67 215.0 COG1409@1|root,COG1409@2|Bacteria,1UQCQ@1239|Firmicutes,4HG8Z@91061|Bacilli,3F483@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase cpdA - - - - - - - - - - - Metallophos CAFIFDFH_00050 1423748.BALB01000007_gene893 1.81e-34 130.0 COG1409@1|root,COG1409@2|Bacteria,1UQCQ@1239|Firmicutes,4HG8Z@91061|Bacilli,3F483@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase cpdA - - - - - - - - - - - Metallophos CAFIFDFH_00051 1423748.BALB01000007_gene893 5.39e-14 70.5 COG1409@1|root,COG1409@2|Bacteria,1UQCQ@1239|Firmicutes,4HG8Z@91061|Bacilli,3F483@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase cpdA - - - - - - - - - - - Metallophos CAFIFDFH_00052 326425.lhe_1143 4.31e-280 764.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,3F3NZ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 CAFIFDFH_00053 405566.lhv_1264 1.29e-91 268.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli,3F6VZ@33958|Lactobacillaceae 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA CAFIFDFH_00054 326425.lhe_1145 3.95e-138 390.0 COG4474@1|root,COG4474@2|Bacteria,1V6SM@1239|Firmicutes,4HJGM@91061|Bacilli,3F4MR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0398 family ypsA - - - - - - - - - - - DUF1273 CAFIFDFH_00055 326425.lhe_1146 9.14e-152 426.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,3F4DG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU CAFIFDFH_00056 326425.lhe_1147 0.0 1389.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F424@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein 1A ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 CAFIFDFH_00057 326425.lhe_1148 1.46e-146 412.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,3F42U@33958|Lactobacillaceae 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD CAFIFDFH_00058 326425.lhe_1149 5.68e-148 417.0 COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,3F4FF@33958|Lactobacillaceae 91061|Bacilli L DnaD domain protein dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 CAFIFDFH_00059 326425.lhe_1150 0.0 902.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,3F4EK@33958|Lactobacillaceae 91061|Bacilli J Asparaginyl-tRNA synthetase asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon CAFIFDFH_00060 326425.lhe_1151 6.04e-117 334.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,3F4MM@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria ypmB - - - - - - - - - - - PepSY CAFIFDFH_00061 326425.lhe_1152 0.0 1818.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,3F4KA@33958|Lactobacillaceae 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII CAFIFDFH_00062 326425.lhe_1153 0.0 2336.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,3F3Z0@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C CAFIFDFH_00063 326425.lhe_1154 0.0 2262.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HK67@91061|Bacilli,3FCA9@33958|Lactobacillaceae 91061|Bacilli L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity rexB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 CAFIFDFH_00064 326425.lhe_1155 6.51e-216 596.0 COG1577@1|root,COG1577@2|Bacteria,1UFCB@1239|Firmicutes,4HG49@91061|Bacilli,3FBNI@33958|Lactobacillaceae 91061|Bacilli I GHMP kinases N terminal domain mvk - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N CAFIFDFH_00065 326425.lhe_1156 1.06e-230 635.0 COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli,3F4B5@33958|Lactobacillaceae 91061|Bacilli I diphosphomevalonate decarboxylase mvaD - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N CAFIFDFH_00066 405566.lhv_1277 1.15e-261 716.0 COG1577@1|root,COG1577@2|Bacteria,1TPKP@1239|Firmicutes,4HC93@91061|Bacilli,3F3RZ@33958|Lactobacillaceae 91061|Bacilli I phosphomevalonate kinase mvaK2 - 2.7.4.2 ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R03245 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N CAFIFDFH_00067 326425.lhe_1158 4.36e-239 657.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,3F3UY@33958|Lactobacillaceae 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh CAFIFDFH_00068 326425.lhe_1159 0.0 914.0 COG0144@1|root,COG0144@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli,3F492@33958|Lactobacillaceae 91061|Bacilli J NOL1 NOP2 sun family protein rsmF - - - - - - - - - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI CAFIFDFH_00069 405566.lhv_1280 3.68e-230 634.0 2EPHD@1|root,33H40@2|Bacteria,1VNCY@1239|Firmicutes,4HYY7@91061|Bacilli,3F495@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - MacB_PCD CAFIFDFH_00070 405566.lhv_1281 3.03e-179 499.0 2E39Q@1|root,32Y99@2|Bacteria,1VQQ8@1239|Firmicutes,4HRY1@91061|Bacilli,3F4UX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00071 326425.lhe_1162 1.48e-133 378.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4IR1W@91061|Bacilli,3FBKY@33958|Lactobacillaceae 91061|Bacilli U Peptidase S24-like - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 CAFIFDFH_00072 1423748.BALB01000007_gene870 7.83e-38 126.0 29PI4@1|root,30AG9@2|Bacteria,1U6MC@1239|Firmicutes,4IGE7@91061|Bacilli,3F858@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00073 405566.lhv_1284 9.06e-137 397.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3NB@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N CAFIFDFH_00074 405566.lhv_1284 2.19e-41 147.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3NB@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N CAFIFDFH_00075 326425.lhe_1165 1.2e-30 115.0 2DKIE@1|root,309JQ@2|Bacteria,1U58N@1239|Firmicutes,4IEZY@91061|Bacilli,3F55M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00076 405566.lhv_0236 2.97e-116 341.0 2DKPF@1|root,30A7K@2|Bacteria,1U6AS@1239|Firmicutes,4IG26@91061|Bacilli,3F7GS@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP CAFIFDFH_00077 405566.lhv_0235 0.0 876.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,3F4I3@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase CAFIFDFH_00078 405566.lhv_0234 8.69e-192 533.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,3F3NH@33958|Lactobacillaceae 91061|Bacilli F pur operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N CAFIFDFH_00079 748671.LCRIS_00221 2.02e-52 165.0 COG4466@1|root,COG4466@2|Bacteria,1VEQM@1239|Firmicutes,4HKF8@91061|Bacilli,3F7D3@33958|Lactobacillaceae 91061|Bacilli S Biofilm formation stimulator VEG veg - - - - - - - - - - - VEG CAFIFDFH_00080 405566.lhv_0232 3.45e-207 573.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,3F3VC@33958|Lactobacillaceae 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD CAFIFDFH_00081 326425.lhe_1856 3.64e-129 367.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,3F64F@33958|Lactobacillaceae 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 CAFIFDFH_00082 405566.lhv_0230 9.48e-190 526.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,3F3N2@33958|Lactobacillaceae 91061|Bacilli L hydrolase, TatD family tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase CAFIFDFH_00083 405566.lhv_0229 0.0 1321.0 COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,3F3XR@33958|Lactobacillaceae 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind CAFIFDFH_00084 326425.lhe_1859 0.0 1670.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HBQJ@91061|Bacilli,3F4E0@33958|Lactobacillaceae 91061|Bacilli P COG0474 Cation transport ATPase mgtA - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase CAFIFDFH_00085 405566.lhv_0227 3.91e-139 394.0 COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4HJVB@91061|Bacilli,3F5HD@33958|Lactobacillaceae 91061|Bacilli S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase CAFIFDFH_00086 326425.lhe_1861 1.09e-118 338.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HEJU@91061|Bacilli,3FC8D@33958|Lactobacillaceae 91061|Bacilli F MafB19-like deaminase comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 CAFIFDFH_00087 1423748.BALB01000008_gene948 2.86e-245 673.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,3F3V6@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b CAFIFDFH_00088 326425.lhe_1863 1.08e-149 420.0 COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HHE2@91061|Bacilli,3F5AJ@33958|Lactobacillaceae 91061|Bacilli E Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP CAFIFDFH_00090 326425.lhe_1865 6.33e-148 417.0 2BFBV@1|root,3294Z@2|Bacteria,1UG72@1239|Firmicutes,4IF41@91061|Bacilli,3F5KI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Abi CAFIFDFH_00091 405566.lhv_0223 2.07e-102 296.0 COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,4HW8H@91061|Bacilli,3F6ZK@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N CAFIFDFH_00092 326425.lhe_1867 8.64e-79 236.0 COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HIUZ@91061|Bacilli,3FB63@33958|Lactobacillaceae 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family hsp - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 CAFIFDFH_00093 405566.lhv_0221 0.0 886.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F3QA@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepE - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 CAFIFDFH_00094 405566.lhv_0216 1.03e-265 728.0 COG0516@1|root,COG0516@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,3F3XN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH CAFIFDFH_00095 326425.lhe_1876 1.2e-153 431.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,3F3PN@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. ypgQ - - ko:K06950 - - - - ko00000 - - - HD CAFIFDFH_00096 405566.lhv_0212 0.0 882.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F3QA@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepC1 - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 CAFIFDFH_00098 405566.lhv_0209 1.33e-70 213.0 2BZTJ@1|root,30A3I@2|Bacteria,1U655@1239|Firmicutes,4IFUX@91061|Bacilli,3F72R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00099 405566.lhv_0208 2.19e-310 845.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,3F48J@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b CAFIFDFH_00100 326425.lhe_1881 0.0 917.0 2A3XC@1|root,30SFQ@2|Bacteria,1UGQV@1239|Firmicutes,4IF8A@91061|Bacilli,3F5YM@33958|Lactobacillaceae 91061|Bacilli S Fibronectin type III domain - - - - - - - - - - - - fn3 CAFIFDFH_00101 405566.lhv_0206 0.0 1907.0 COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,4HBY6@91061|Bacilli,3F3NY@33958|Lactobacillaceae 91061|Bacilli M Sulfatase XK27_08315 - - - - - - - - - - - Sulfatase CAFIFDFH_00102 405566.lhv_0205 2.73e-146 412.0 COG0344@1|root,COG0344@2|Bacteria,1VAFC@1239|Firmicutes,4HMJZ@91061|Bacilli,3F5HQ@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY1 - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf CAFIFDFH_00103 405566.lhv_0204 1.01e-255 702.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr CAFIFDFH_00104 405566.lhv_0203 4.62e-131 372.0 COG2017@1|root,COG2017@2|Bacteria,1U5EB@1239|Firmicutes,4IF5R@91061|Bacilli,3F5Q4@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase - - - - - - - - - - - - Aldose_epim CAFIFDFH_00105 405566.lhv_0202 3.47e-142 401.0 COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,4HCIJ@91061|Bacilli,3F46I@33958|Lactobacillaceae 91061|Bacilli O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 CAFIFDFH_00106 1423748.BALB01000008_gene931 1.57e-171 478.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,3F3SK@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 CAFIFDFH_00107 326425.lhe_1888 1.43e-150 425.0 2E0R1@1|root,32W9E@2|Bacteria,1U59S@1239|Firmicutes,4IF1B@91061|Bacilli,3F5B0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00108 405566.lhv_1154 0.0 1065.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli,3F4HM@33958|Lactobacillaceae 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase CAFIFDFH_00109 326425.lhe_0639 1.99e-235 647.0 COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,4HB4T@91061|Bacilli,3F455@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid ykpB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C CAFIFDFH_00110 326425.lhe_0638 1.31e-290 792.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,3F4TW@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase mtnE - - ko:K08969 ko00270,ko01100,map00270,map01100 M00034 R07396 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CAFIFDFH_00111 405566.lhv_0568 2.72e-193 535.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,3F4ND@33958|Lactobacillaceae 91061|Bacilli S Carbon-nitrogen hydrolase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase CAFIFDFH_00112 405566.lhv_0569 9.77e-48 154.0 COG0516@1|root,COG0516@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,3F3XN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH CAFIFDFH_00113 1423767.BALU01000001_gene1588 4.19e-13 68.6 COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,4HCSJ@91061|Bacilli,3F51K@33958|Lactobacillaceae 91061|Bacilli S cog cog1373 - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CAFIFDFH_00114 326425.lhe_1910 4.64e-171 478.0 COG0789@1|root,COG0789@2|Bacteria,1V05W@1239|Firmicutes,4HSX6@91061|Bacilli,3F4R7@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 CAFIFDFH_00115 326425.lhe_1911 3.82e-294 805.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,3F44D@33958|Lactobacillaceae 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease CAFIFDFH_00116 1033837.WANG_1752 2.73e-71 225.0 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli,3F6CN@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 CAFIFDFH_00117 1423748.BALB01000025_gene1786 2.57e-20 90.5 COG1201@1|root,COG1201@2|Bacteria,1UHYQ@1239|Firmicutes,4HD4E@91061|Bacilli,3F42E@33958|Lactobacillaceae 91061|Bacilli L DEAD DEAH box helicase - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C CAFIFDFH_00118 326425.lhe_0509 3.9e-79 235.0 29P2Q@1|root,30A0W@2|Bacteria,1U61M@1239|Firmicutes,4IFQH@91061|Bacilli,3F6U2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00119 326425.lhe_0510 2.93e-181 504.0 COG4295@1|root,COG4295@2|Bacteria,1TSFT@1239|Firmicutes,4HGDA@91061|Bacilli,3F6RG@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2263) - - - - - - - - - - - - DUF2263 CAFIFDFH_00120 1033837.WANG_1181 3.85e-62 200.0 COG5464@1|root,COG5464@2|Bacteria,1V1A7@1239|Firmicutes,4HG0B@91061|Bacilli,3F655@33958|Lactobacillaceae 91061|Bacilli S PD-(D/E)XK nuclease family transposase - - - - - - - - - - - - PDDEXK_2 CAFIFDFH_00123 405566.lhv_0263 9.98e-91 275.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,3F4RA@33958|Lactobacillaceae 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut CAFIFDFH_00124 326425.lhe_0566 7.86e-207 571.0 COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,4HCHJ@91061|Bacilli,3F52H@33958|Lactobacillaceae 91061|Bacilli S Phospholipase, patatin family - - - - - - - - - - - - Patatin CAFIFDFH_00125 326425.lhe_0565 0.0 1669.0 COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,4HC2J@91061|Bacilli,3F3TZ@33958|Lactobacillaceae 91061|Bacilli G Phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N CAFIFDFH_00126 405566.lhv_1685 1.06e-57 178.0 2DKPI@1|root,30A82@2|Bacteria,1U6BA@1239|Firmicutes,4IG2X@91061|Bacilli,3F7I5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00127 405566.lhv_1684 1.19e-44 145.0 COG2337@1|root,COG2337@2|Bacteria,1U642@1239|Firmicutes,4IFTM@91061|Bacilli,3F6ZN@33958|Lactobacillaceae 91061|Bacilli T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin CAFIFDFH_00128 525365.HMPREF0548_0311 8.65e-310 845.0 COG0675@1|root,COG0675@2|Bacteria,1TQAH@1239|Firmicutes,4IRBD@91061|Bacilli,3FBNH@33958|Lactobacillaceae 91061|Bacilli L Probable transposase - - - - - - - - - - - - OrfB_IS605,OrfB_Zn_ribbon CAFIFDFH_00129 1423754.BALY01000020_gene763 5.43e-18 82.0 COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,4HFD7@91061|Bacilli,3F4I5@33958|Lactobacillaceae 91061|Bacilli S Fic/DOC family - - - - - - - - - - - - Fic,HTH_17 CAFIFDFH_00130 1033837.WANG_1127 1.19e-91 281.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli,3F4RB@33958|Lactobacillaceae 91061|Bacilli L PFAM Transposase, IS204 IS1001 IS1096 IS1165 tnp2 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 CAFIFDFH_00131 1033837.WANG_1126 7.28e-42 137.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3F7FW@33958|Lactobacillaceae 91061|Bacilli K Cold shock protein cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD CAFIFDFH_00136 1033837.WANG_1117 3.41e-35 131.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator qacA - - - - - - - - - - - MFS_1 CAFIFDFH_00137 1033837.WANG_1117 2.98e-14 72.4 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator qacA - - - - - - - - - - - MFS_1 CAFIFDFH_00138 1033837.WANG_1117 1.33e-44 158.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator qacA - - - - - - - - - - - MFS_1 CAFIFDFH_00139 1423767.BALU01000002_gene1646 3.04e-73 232.0 COG1455@1|root,COG1455@2|Bacteria,1VTVX@1239|Firmicutes,4HFKM@91061|Bacilli,3FC6X@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts23C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC CAFIFDFH_00140 326425.lhe_0890 4.15e-172 480.0 COG2188@1|root,COG2188@2|Bacteria,1V0UW@1239|Firmicutes,4HD10@91061|Bacilli,3FC8M@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03492 - - - - ko00000,ko03000 - - - GntR,UTRA CAFIFDFH_00141 891391.LAC30SC_04440 5.36e-145 421.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 CAFIFDFH_00142 405566.lhv_0934 6.09e-162 454.0 COG1051@1|root,COG4111@1|root,COG1051@2|Bacteria,COG4111@2|Bacteria,1TST7@1239|Firmicutes,4HEFP@91061|Bacilli,3F54T@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX CAFIFDFH_00143 326425.lhe_1185 2.32e-197 547.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,3F3WK@33958|Lactobacillaceae 91061|Bacilli F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase CAFIFDFH_00144 326425.lhe_1186 5.68e-67 204.0 2DVJ8@1|root,33W59@2|Bacteria,1UI90@1239|Firmicutes,4HD3X@91061|Bacilli,3F5JD@33958|Lactobacillaceae 91061|Bacilli S Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 CAFIFDFH_00145 326425.lhe_1243 1.07e-209 579.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,3F3PH@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 yitT - - - - - - - - - - - DUF2179,YitT_membrane CAFIFDFH_00146 405566.lhv_2522 1.32e-86 256.0 29TNS@1|root,30EWM@2|Bacteria,1U551@1239|Firmicutes,4IEWA@91061|Bacilli,3F4Q6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00147 405566.lhv_1158 0.0 1991.0 COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4HB5A@91061|Bacilli,3F50Q@33958|Lactobacillaceae 91061|Bacilli V Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoR124_C,HSDR_N,ResIII CAFIFDFH_00148 405566.lhv_1918 3.79e-125 357.0 COG0503@1|root,COG0503@2|Bacteria,1V9BZ@1239|Firmicutes,4IQPM@91061|Bacilli,3FBI8@33958|Lactobacillaceae 91061|Bacilli F Phosphoribosyl transferase domain - - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran CAFIFDFH_00149 405566.lhv_1917 2.2e-233 645.0 COG0659@1|root,COG0659@2|Bacteria,1UY33@1239|Firmicutes,4HDN5@91061|Bacilli,3F41X@33958|Lactobacillaceae 91061|Bacilli P secondary active sulfate transmembrane transporter activity - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease CAFIFDFH_00150 405566.lhv_1916 3.59e-136 385.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve CAFIFDFH_00151 326425.lhe_0298 3.05e-160 448.0 COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,4HBVI@91061|Bacilli,3F59R@33958|Lactobacillaceae 91061|Bacilli C Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR CAFIFDFH_00152 326425.lhe_0299 0.0 1528.0 COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli,3F3VW@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 CAFIFDFH_00153 326425.lhe_0300 2.49e-114 327.0 COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,3F4W2@33958|Lactobacillaceae 91061|Bacilli H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS CAFIFDFH_00154 405566.lhv_1911 5.51e-156 441.0 COG1396@1|root,COG1396@2|Bacteria,1VD8E@1239|Firmicutes,4HMD2@91061|Bacilli,3F61C@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator ywdE - - ko:K20375 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 CAFIFDFH_00155 405566.lhv_1910 1.57e-280 769.0 COG0477@1|root,COG0477@2|Bacteria,1UI8U@1239|Firmicutes,4ISG9@91061|Bacilli,3FBSV@33958|Lactobacillaceae 91061|Bacilli EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 CAFIFDFH_00156 405566.lhv_1909 2.28e-149 424.0 COG1396@1|root,COG1396@2|Bacteria,1VD8E@1239|Firmicutes,4HMD2@91061|Bacilli,3F61C@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator ywdE - - ko:K20375 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 CAFIFDFH_00159 326425.lhe_0317 4.24e-217 599.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,3F4VD@33958|Lactobacillaceae 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family mccA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00609 R00897,R03601,R04859,R10305 RC00020,RC00069,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02385 PALP CAFIFDFH_00160 326425.lhe_0318 7.19e-280 765.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,3F3Y2@33958|Lactobacillaceae 91061|Bacilli E cystathionine mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP CAFIFDFH_00161 326425.lhe_0319 5.17e-123 351.0 COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli,3F63E@33958|Lactobacillaceae 91061|Bacilli E Bacterial transferase hexapeptide (six repeats) cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,SATase_N CAFIFDFH_00162 1400520.LFAB_16000 1.53e-18 83.2 COG1028@1|root,COG1028@2|Bacteria,1TRQC@1239|Firmicutes,4HD7P@91061|Bacilli,3F4FH@33958|Lactobacillaceae 91061|Bacilli IQ reductase dar - 1.1.1.304,1.1.1.76 ko:K03366 ko00650,map00650 - R02855,R02946,R03707,R09078,R10505 RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 CAFIFDFH_00163 405566.lhv_1900 4.39e-250 685.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,3F3P1@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm CAFIFDFH_00164 1033837.WANG_1755 1.39e-96 281.0 COG1780@1|root,COG1780@2|Bacteria 2|Bacteria F Probably involved in ribonucleotide reductase function nrdI GO:0000166,GO:0003674,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0019538,GO:0032553,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI CAFIFDFH_00165 326425.lhe_0323 0.0 1409.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,3F3XG@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN CAFIFDFH_00166 1033837.WANG_1757 1.96e-54 170.0 29P3Y@1|root,30A25@2|Bacteria,1U639@1239|Firmicutes,4IFSM@91061|Bacilli,3F6XR@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun CAFIFDFH_00167 1033837.WANG_0325 7.05e-76 239.0 COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,4HBFK@91061|Bacilli,3F53D@33958|Lactobacillaceae 91061|Bacilli S ABC transporter yjcA - - ko:K19350 ko02010,map02010 - - - ko00000,ko00001,ko01504,ko02000 3.A.1.121 - - ABC_tran,ABC_tran_Xtn CAFIFDFH_00169 1033837.WANG_0327 0.0 1483.0 COG0476@1|root,COG0476@2|Bacteria,1V9AZ@1239|Firmicutes,4HIYB@91061|Bacilli 91061|Bacilli H ThiF family - - - - - - - - - - - - ThiF CAFIFDFH_00170 1033837.WANG_0328 0.0 997.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HIAU@91061|Bacilli,3F3JJ@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran CAFIFDFH_00171 1033837.WANG_0329 3.04e-93 280.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HAYI@91061|Bacilli,3FB5V@33958|Lactobacillaceae 91061|Bacilli L COG2826 Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve CAFIFDFH_00172 1033837.WANG_1282 4.53e-191 535.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,3F4RA@33958|Lactobacillaceae 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut CAFIFDFH_00173 405566.lhv_1245 6.12e-46 157.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,3F4RA@33958|Lactobacillaceae 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut CAFIFDFH_00175 326425.lhe_0012 3e-220 618.0 COG1132@1|root,COG1132@2|Bacteria,1UV7Z@1239|Firmicutes,4I2UY@91061|Bacilli,3F5Y3@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran CAFIFDFH_00176 326425.lhe_0015 1.41e-111 348.0 COG0515@1|root,COG0515@2|Bacteria,1TSH3@1239|Firmicutes,4HGIJ@91061|Bacilli,3F7MT@33958|Lactobacillaceae 91061|Bacilli KLT Protein kinase domain - - - - - - - - - - - - LANC_like,Pkinase CAFIFDFH_00179 326425.lhe_1830 0.0 1045.0 COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,3F3NV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase CAFIFDFH_00181 405566.lhv_1361 1.25e-41 147.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 CAFIFDFH_00182 326425.lhe_0269 0.0 887.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HBZF@91061|Bacilli,3FC6T@33958|Lactobacillaceae 91061|Bacilli C Pyridine nucleotide-disulfide oxidoreductase - - 1.8.1.7 ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim CAFIFDFH_00183 326425.lhe_1083 4.45e-208 579.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase flp - - - - - - - - - - - Beta-lactamase,SLH CAFIFDFH_00184 326425.lhe_1082 0.0 943.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,3F3UV@33958|Lactobacillaceae 91061|Bacilli E dipeptidase PepV pepV - 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CAFIFDFH_00185 326425.lhe_0400 2.74e-196 547.0 COG0791@1|root,COG0791@2|Bacteria,1V5H7@1239|Firmicutes,4HMYU@91061|Bacilli,3FBE5@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 CAFIFDFH_00187 525365.HMPREF0548_0222 7.59e-260 715.0 COG2271@1|root,COG2271@2|Bacteria,1TPJB@1239|Firmicutes,4HEY7@91061|Bacilli,3F4VX@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CAFIFDFH_00188 525365.HMPREF0548_0221 2.04e-59 183.0 2DN64@1|root,32VRU@2|Bacteria,1UPY3@1239|Firmicutes,4IVD5@91061|Bacilli,3FC0U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00189 525365.HMPREF0548_0220 9.6e-35 119.0 29PJD@1|root,30AHI@2|Bacteria,1VC64@1239|Firmicutes 1239|Firmicutes S Domain of unknown function (DUF4160) - - - - - - - - - - - - DUF4160 CAFIFDFH_00190 326425.lhe_1654 1.25e-147 415.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,3F3KD@33958|Lactobacillaceae 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like CAFIFDFH_00191 326425.lhe_1655 2.92e-190 528.0 COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli,3F446@33958|Lactobacillaceae 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race CAFIFDFH_00192 1423748.BALB01000002_gene203 3.63e-91 266.0 COG1719@1|root,COG1719@2|Bacteria,1VD7N@1239|Firmicutes,4HKV3@91061|Bacilli,3F7ZI@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2507) yslB - - - - - - - - - - - DUF2507 CAFIFDFH_00193 326425.lhe_0514 1.98e-100 295.0 COG2188@1|root,COG2188@2|Bacteria,1UYYY@1239|Firmicutes,4HGI6@91061|Bacilli,3F5F4@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA CAFIFDFH_00194 326425.lhe_0515 1.16e-289 789.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,3F40F@33958|Lactobacillaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 CAFIFDFH_00195 326425.lhe_1912 4.08e-306 835.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,3F3X1@33958|Lactobacillaceae 91061|Bacilli P ammonium transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp CAFIFDFH_00196 405566.lhv_0265 6.23e-19 85.1 2DNGW@1|root,32XFG@2|Bacteria,1TZ4U@1239|Firmicutes,4IGM1@91061|Bacilli,3F8G9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00197 326425.lhe_1825 6.9e-298 812.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,3F4C1@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT CAFIFDFH_00198 1033837.WANG_0930 2.75e-136 399.0 COG0531@1|root,COG0531@2|Bacteria,1VT70@1239|Firmicutes,4HUMC@91061|Bacilli,3FCAG@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 CAFIFDFH_00199 1033837.WANG_0930 1.79e-171 491.0 COG0531@1|root,COG0531@2|Bacteria,1VT70@1239|Firmicutes,4HUMC@91061|Bacilli,3FCAG@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 CAFIFDFH_00200 748671.LCRIS_00733 1.32e-20 90.1 COG0531@1|root,COG0531@2|Bacteria,1VT70@1239|Firmicutes,4HUMC@91061|Bacilli,3FCAG@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 CAFIFDFH_00201 326425.lhe_0733 1.03e-236 650.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,Hydrolase_4 CAFIFDFH_00202 1423748.BALB01000001_gene134 9.84e-149 429.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 CAFIFDFH_00203 1423748.BALB01000001_gene134 5.27e-160 458.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 CAFIFDFH_00204 1423748.BALB01000001_gene134 8.68e-28 111.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 CAFIFDFH_00205 326425.lhe_0731 0.0 1155.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts33BCA - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC CAFIFDFH_00206 1423748.BALB01000001_gene136 7.38e-81 245.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,3F4SJ@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain bglG5 - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD CAFIFDFH_00207 1423748.BALB01000001_gene136 2.28e-81 247.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,3F4SJ@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain bglG5 - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD CAFIFDFH_00208 405566.lhv_0764 2.29e-263 722.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,4HA91@91061|Bacilli,3F3V2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase CAFIFDFH_00209 326425.lhe_0728 2.06e-112 322.0 COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli,3F74A@33958|Lactobacillaceae 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family ptpA - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc CAFIFDFH_00210 405566.lhv_0762 1.86e-153 432.0 29NKW@1|root,309IV@2|Bacteria,1U56K@1239|Firmicutes,4IEXT@91061|Bacilli,3F4Y0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00211 326425.lhe_0726 2.8e-190 528.0 COG0561@1|root,COG0561@2|Bacteria,1U3W2@1239|Firmicutes,4HM9S@91061|Bacilli,3FC85@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 CAFIFDFH_00212 326425.lhe_0725 2.06e-192 534.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,3F55S@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - - - - - - - - - - - Hydrolase_3 CAFIFDFH_00213 326425.lhe_0724 0.0 887.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,3F3W5@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV CAFIFDFH_00214 405566.lhv_0758 5.29e-218 603.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,3F41C@33958|Lactobacillaceae 91061|Bacilli S YbbR-like protein ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR CAFIFDFH_00215 326425.lhe_0722 8.69e-194 538.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,3F4N3@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N CAFIFDFH_00216 326425.lhe_0721 6.98e-266 727.0 COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli,3F3W1@33958|Lactobacillaceae 91061|Bacilli P ABC transporter potD - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSB619.SA_RS05395 SBP_bac_8 CAFIFDFH_00217 326425.lhe_0720 1.31e-179 501.0 COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli,3F3ZN@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease potC - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 CAFIFDFH_00218 405566.lhv_0754 6.45e-175 489.0 COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,4HAYS@91061|Bacilli,3F4CM@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease potB - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 CAFIFDFH_00219 326425.lhe_0718 4.51e-262 718.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,3F40H@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 - iSB619.SA_RS05380 ABC_tran,TOBE_2 CAFIFDFH_00220 405566.lhv_0752 1.47e-210 582.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,3F40T@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C CAFIFDFH_00221 1423748.BALB01000001_gene151 7.47e-128 363.0 COG0847@1|root,COG0847@2|Bacteria,1V57H@1239|Firmicutes,4HI1V@91061|Bacilli,3F42Z@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T CAFIFDFH_00222 326425.lhe_0715 1.87e-118 338.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,3F3MR@33958|Lactobacillaceae 91061|Bacilli O Hydrolase, P-loop family ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE CAFIFDFH_00223 326425.lhe_0714 3.84e-233 642.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,3F3MW@33958|Lactobacillaceae 91061|Bacilli C phosphate acetyltransferase pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB CAFIFDFH_00224 326425.lhe_0713 2.33e-174 485.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,3F3W0@33958|Lactobacillaceae 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG CAFIFDFH_00225 326425.lhe_0712 1.52e-205 569.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,3F58Y@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase ycsE - - - - - - - - - - - Hydrolase_3 CAFIFDFH_00226 326425.lhe_0711 4.35e-125 355.0 29NVF@1|root,309TI@2|Bacteria,1U5NS@1239|Firmicutes,4IFDC@91061|Bacilli,3F68I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00227 405566.lhv_0745 1.91e-183 509.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,3F494@33958|Lactobacillaceae 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM CAFIFDFH_00228 326425.lhe_0709 6.01e-288 786.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,3F3SC@33958|Lactobacillaceae 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK CAFIFDFH_00229 1423748.BALB01000001_gene161 2.86e-244 671.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,3F3JS@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N CAFIFDFH_00230 326425.lhe_0707 1.11e-239 659.0 COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,3F53Y@33958|Lactobacillaceae 91061|Bacilli K Putative sugar-binding domain cggR - - ko:K05311 - - - - ko00000,ko03000 - - - Sugar-bind CAFIFDFH_00247 405566.lhv_0475 6.22e-86 259.0 COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,4ISD2@91061|Bacilli,3F53H@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC CAFIFDFH_00248 405566.lhv_0475 3.19e-60 192.0 COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,4ISD2@91061|Bacilli,3F53H@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC CAFIFDFH_00249 748671.LCRIS_01512 4.26e-56 184.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,3F4UD@33958|Lactobacillaceae 91061|Bacilli G invertase sacA - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 iYO844.BSU38040 Glyco_hydro_32C,Glyco_hydro_32N CAFIFDFH_00250 405566.lhv_1082 2.61e-195 541.0 COG4974@1|root,COG4974@2|Bacteria,1UFH8@1239|Firmicutes,4IES1@91061|Bacilli,3F3KV@33958|Lactobacillaceae 91061|Bacilli L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Phage_int_SAM_1 CAFIFDFH_00251 931276.Cspa_c45520 1.3e-13 71.6 COG0438@1|root,COG0438@2|Bacteria,1UTTV@1239|Firmicutes,25GKM@186801|Clostridia 186801|Clostridia M Glycosyltransferase WbsX - - - - - - - - - - - - Glyco_tran_WbsX CAFIFDFH_00252 545696.HOLDEFILI_02049 1.01e-26 117.0 COG0438@1|root,COG0438@2|Bacteria,1TRRW@1239|Firmicutes 1239|Firmicutes M Spore coat protein cotSA GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K06338 - - - - ko00000 - - - Glyco_transf_4,Glycos_transf_1 CAFIFDFH_00253 1033837.WANG_p1012 8.53e-64 206.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 CAFIFDFH_00254 405566.lhv_0447 0.0 931.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,3FCFA@33958|Lactobacillaceae 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 CAFIFDFH_00255 1423748.BALB01000010_gene1069 1.47e-32 124.0 COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,3F4M8@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DUF772 CAFIFDFH_00257 1423754.BALY01000067_gene768 6.31e-60 197.0 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli,3F6CN@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 CAFIFDFH_00258 1211035.CD30_07100 0.00042 46.6 2DR4Q@1|root,33A5I@2|Bacteria,1V7AE@1239|Firmicutes,4HKQS@91061|Bacilli 91061|Bacilli S EpsG family - - - - - - - - - - - - EpsG CAFIFDFH_00259 405566.lhv_0021 8.33e-227 624.0 COG1307@1|root,COG1307@2|Bacteria,1V289@1239|Firmicutes,4I3AR@91061|Bacilli,3F4D9@33958|Lactobacillaceae 91061|Bacilli S DegV family degV1 - - - - - - - - - - - DegV CAFIFDFH_00261 97137.C821_00801 3.16e-32 122.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HBZF@91061|Bacilli,3FC6T@33958|Lactobacillaceae 91061|Bacilli C Pyridine nucleotide-disulfide oxidoreductase - - 1.8.1.7 ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim CAFIFDFH_00262 353496.LBU_0210 5.16e-311 846.0 COG3410@1|root,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,4HBI0@91061|Bacilli,3F47M@33958|Lactobacillaceae 91061|Bacilli N Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075,GIY-YIG CAFIFDFH_00263 525365.HMPREF0548_1074 5.94e-42 149.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,3F4BG@33958|Lactobacillaceae 91061|Bacilli E amino acid ybgF - - ko:K02205,ko:K03293,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - - AA_permease CAFIFDFH_00264 353496.LBU_0209 4.95e-247 679.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,3F4BG@33958|Lactobacillaceae 91061|Bacilli E amino acid ybgF - - ko:K02205,ko:K03293,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - - AA_permease CAFIFDFH_00265 405566.lhv_1172 5.7e-202 561.0 COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli,3F4UT@33958|Lactobacillaceae 91061|Bacilli H homocysteine S-methyltransferase mmuM - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans CAFIFDFH_00266 405566.lhv_1171 3.12e-295 804.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,3FC42@33958|Lactobacillaceae 91061|Bacilli E Peptidase family M20/M25/M40 amd - - - - - - - - - - - M20_dimer,Peptidase_M20 CAFIFDFH_00267 326425.lhe_1069 5.29e-300 820.0 COG0531@1|root,COG0531@2|Bacteria,1TQ48@1239|Firmicutes,4HBGT@91061|Bacilli,3F3YJ@33958|Lactobacillaceae 91061|Bacilli E amino acid steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 CAFIFDFH_00268 353496.LBU_0205 4.09e-80 238.0 COG3576@1|root,COG3576@2|Bacteria,1VW4G@1239|Firmicutes,4HW37@91061|Bacilli,3F6IW@33958|Lactobacillaceae 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx CAFIFDFH_00269 326425.lhe_1067 0.0 1303.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F4CX@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N CAFIFDFH_00270 326425.lhe_1066 1.74e-196 547.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase CAFIFDFH_00271 326425.lhe_1065 0.0 1040.0 2BW99@1|root,2Z7PD@2|Bacteria,1TQFA@1239|Firmicutes,4HC1J@91061|Bacilli,3F4D7@33958|Lactobacillaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score XK27_11280 - - - - - - - - - - - - CAFIFDFH_00273 1033837.WANG_1868 3.66e-229 638.0 COG0226@1|root,COG0226@2|Bacteria,1V2DG@1239|Firmicutes,4HFZU@91061|Bacilli,3F623@33958|Lactobacillaceae 91061|Bacilli P T5orf172 yeeC - - - - - - - - - - - T5orf172 CAFIFDFH_00274 713605.ADHG01000001_gene218 0.0 1159.0 COG1061@1|root,COG1061@2|Bacteria,1TQUR@1239|Firmicutes,4HDB4@91061|Bacilli,3F4UP@33958|Lactobacillaceae 91061|Bacilli L DEAD-like helicases superfamily - - - - - - - - - - - - Helicase_C,ResIII CAFIFDFH_00275 713605.ADHG01000001_gene219 2.83e-150 424.0 28PY0@1|root,32Q2K@2|Bacteria,1U8E2@1239|Firmicutes,4IIC0@91061|Bacilli,3FAVV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00276 1033837.WANG_1865 0.0 1321.0 COG1002@1|root,COG1002@2|Bacteria,1TRZH@1239|Firmicutes,4HE9W@91061|Bacilli,3F4XU@33958|Lactobacillaceae 91061|Bacilli V Type II restriction enzyme, methylase subunits yeeA - - - - - - - - - - - N6_Mtase CAFIFDFH_00277 326425.lhe_1062 0.0 913.0 COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,4HF7F@91061|Bacilli,3F57U@33958|Lactobacillaceae 91061|Bacilli S Archaea bacterial proteins of unknown function - - - ko:K06921 - - - - ko00000 - - - ATPase_2,DUF234 CAFIFDFH_00278 326425.lhe_1061 1.83e-40 135.0 2ACE2@1|root,311ZJ@2|Bacteria,1U5CK@1239|Firmicutes,4IF3R@91061|Bacilli,3F5IZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF4767 CAFIFDFH_00279 97137.C821_00150 1.3e-84 261.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F55P@33958|Lactobacillaceae 91061|Bacilli L transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon CAFIFDFH_00280 257314.LJ_0692 1.13e-21 94.7 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F55P@33958|Lactobacillaceae 91061|Bacilli L transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon CAFIFDFH_00281 257314.LJ_0692 1.26e-76 242.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F55P@33958|Lactobacillaceae 91061|Bacilli L transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon CAFIFDFH_00282 353496.LBU_0896 2.02e-107 310.0 2B1UF@1|root,31UAF@2|Bacteria,1V4WF@1239|Firmicutes,4HI2Y@91061|Bacilli,3F5V0@33958|Lactobacillaceae 91061|Bacilli S An automated process has identified a potential problem with this gene model - - - - - - - - - - - - - CAFIFDFH_00283 405566.lhv_1162 2.86e-179 501.0 arCOG09719@1|root,2Z7NA@2|Bacteria,1TSE4@1239|Firmicutes,4HE46@91061|Bacilli,3F5Z4@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3100) - - - - - - - - - - - - DUF3100 CAFIFDFH_00284 353496.LBU_0898 7.39e-314 853.0 COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HE6F@91061|Bacilli,3F5DP@33958|Lactobacillaceae 91061|Bacilli S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 CAFIFDFH_00285 1423748.BALB01000016_gene1461 2.01e-14 70.5 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4IQ8I@91061|Bacilli,3FBH0@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA CAFIFDFH_00286 326425.lhe_0514 9.16e-17 76.6 COG2188@1|root,COG2188@2|Bacteria,1UYYY@1239|Firmicutes,4HGI6@91061|Bacilli,3F5F4@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA CAFIFDFH_00287 326425.lhe_1658 3.11e-71 214.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F6Y3@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin CAFIFDFH_00288 326425.lhe_1657 8.79e-67 204.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,3F6YZ@33958|Lactobacillaceae 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL CAFIFDFH_00289 891391.LAC30SC_10640 5.05e-168 477.0 COG3547@1|root,COG3547@2|Bacteria,1TP4A@1239|Firmicutes,4HDAB@91061|Bacilli,3F40X@33958|Lactobacillaceae 91061|Bacilli L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 CAFIFDFH_00290 405566.lhv_0570 2.91e-147 415.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli,3F4DZ@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair - - - - - - - - - - - - HTH_38,rve CAFIFDFH_00291 525365.HMPREF0548_0610 6.8e-46 156.0 2CJHH@1|root,32SA1@2|Bacteria,1V6G9@1239|Firmicutes,4HIZ6@91061|Bacilli,3F5FF@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 CAFIFDFH_00292 326425.lhe_0439 1.15e-125 357.0 2A3Q0@1|root,30S7H@2|Bacteria,1U63K@1239|Firmicutes,4IFT0@91061|Bacilli,3F6YD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00293 405566.lhv_0237 6.87e-61 198.0 2DKIG@1|root,309K1@2|Bacteria,1U593@1239|Firmicutes,4IF0E@91061|Bacilli,3F586@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - SLAP CAFIFDFH_00294 326425.lhe_0931 1.04e-125 357.0 COG1881@1|root,COG1881@2|Bacteria,1VJEE@1239|Firmicutes,4IRQB@91061|Bacilli,3FBPI@33958|Lactobacillaceae 91061|Bacilli S Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP CAFIFDFH_00295 326425.lhe_0930 9.28e-317 864.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,4HU4D@91061|Bacilli,3F4FR@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE,ThrE_2 CAFIFDFH_00296 326425.lhe_0929 8.03e-229 630.0 COG2390@1|root,COG2390@2|Bacteria,1VSYQ@1239|Firmicutes,4HU6A@91061|Bacilli,3FCBZ@33958|Lactobacillaceae 91061|Bacilli K Putative sugar-binding domain citR - - - - - - - - - - - Sugar-bind CAFIFDFH_00297 326425.lhe_0928 3.15e-22 85.9 29PV8@1|root,30ATG@2|Bacteria,1U734@1239|Firmicutes,4IGXN@91061|Bacilli,3F8WW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00298 405566.lhv_1001 6.67e-86 253.0 29PNX@1|root,30AM4@2|Bacteria,1U6UG@1239|Firmicutes,4IGNA@91061|Bacilli,3F8I6@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function DUF1828 - - - - - - - - - - - - DUF1828 CAFIFDFH_00299 326425.lhe_0926 3.66e-115 331.0 COG4720@1|root,COG4720@2|Bacteria,1V1GT@1239|Firmicutes,4HGAE@91061|Bacilli,3F5A7@33958|Lactobacillaceae 91061|Bacilli S UPF0397 protein - - - ko:K16924 - M00582 - - ko00000,ko00002,ko02000 3.A.1.29 - - ECF-ribofla_trS CAFIFDFH_00300 326425.lhe_0925 1.09e-185 528.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,3F4XP@33958|Lactobacillaceae 91061|Bacilli P ABC transporter, ATP-binding protein ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 CAFIFDFH_00301 326425.lhe_0924 1.37e-185 525.0 COG0619@1|root,COG0619@2|Bacteria,1TPMV@1239|Firmicutes,4HBTW@91061|Bacilli,3F3Y9@33958|Lactobacillaceae 91061|Bacilli P cobalt transport cbiQ - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iSB619.SA_RS14165 CbiQ CAFIFDFH_00302 326425.lhe_0923 1.44e-24 92.4 29PJU@1|root,30AHZ@2|Bacteria,1U6Q0@1239|Firmicutes,4IGGY@91061|Bacilli,3F8A1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00303 326425.lhe_0922 7.19e-93 272.0 COG2707@1|root,COG2707@2|Bacteria,1V7JN@1239|Firmicutes,4HINS@91061|Bacilli,3F68U@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF441) ytwI - - - - - - - - - - - DUF441 CAFIFDFH_00304 405566.lhv_1245 9.12e-282 770.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,3F4RA@33958|Lactobacillaceae 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut CAFIFDFH_00305 326425.lhe_0921 3e-168 471.0 2DBU6@1|root,2ZB4C@2|Bacteria,1VNWP@1239|Firmicutes,4HRN6@91061|Bacilli,3F51G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Gram_pos_anchor CAFIFDFH_00306 326425.lhe_0920 0.0 991.0 COG3051@1|root,COG3051@2|Bacteria,1TPN3@1239|Firmicutes,4HAE1@91061|Bacilli,3F4EA@33958|Lactobacillaceae 91061|Bacilli H Citrate (pro-3S)-lyase alpha chain citF - 2.8.3.10 ko:K01643 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - CitF CAFIFDFH_00307 1423748.BALB01000010_gene1076 3.09e-215 594.0 COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,4HD40@91061|Bacilli,3F47Q@33958|Lactobacillaceae 91061|Bacilli G Belongs to the HpcH HpaI aldolase family citE - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI CAFIFDFH_00308 326425.lhe_0918 2.27e-59 183.0 COG3052@1|root,COG3052@2|Bacteria,1VEZZ@1239|Firmicutes,4HNXD@91061|Bacilli,3F7FR@33958|Lactobacillaceae 91061|Bacilli C Covalent carrier of the coenzyme of citrate lyase citD - - ko:K01646 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001 - - - ACP CAFIFDFH_00309 405566.lhv_0987 3.37e-249 684.0 COG3053@1|root,COG3053@2|Bacteria,1TSGQ@1239|Firmicutes,4HC6Q@91061|Bacilli,3F4H7@33958|Lactobacillaceae 91061|Bacilli H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase citC - 6.2.1.22 ko:K01910 ko02020,map02020 - R04449 RC00012,RC00039 ko00000,ko00001,ko01000 - - - Acetyltransf_10,Citrate_ly_lig CAFIFDFH_00310 326425.lhe_0916 2.53e-198 548.0 COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,4HMJ7@91061|Bacilli,3F4FI@33958|Lactobacillaceae 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 CAFIFDFH_00311 326425.lhe_0915 0.0 948.0 COG0471@1|root,COG0471@2|Bacteria,1TSGE@1239|Firmicutes,4HDE4@91061|Bacilli,3F4RH@33958|Lactobacillaceae 91061|Bacilli P Sodium:sulfate symporter transmembrane region citP - - ko:K03319 - - - - ko00000 2.A.47 - - Na_sulph_symp CAFIFDFH_00312 326425.lhe_0914 0.0 889.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F5DQ@33958|Lactobacillaceae 91061|Bacilli E Peptidase C1-like family pepC4 - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 CAFIFDFH_00313 405566.lhv_0980 2.46e-85 254.0 29X4C@1|root,30IT6@2|Bacteria,1UJGB@1239|Firmicutes,4IT92@91061|Bacilli,3F6JZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00314 1033837.WANG_0753 1.7e-51 176.0 29X4C@1|root,30IT6@2|Bacteria,1UJGB@1239|Firmicutes,4IT92@91061|Bacilli,3F6JZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00315 272621.LBA1634 4.61e-83 293.0 COG2373@1|root,COG3064@1|root,COG2373@2|Bacteria,COG3064@2|Bacteria,1UHXY@1239|Firmicutes,4ISAC@91061|Bacilli,3F52E@33958|Lactobacillaceae 91061|Bacilli M Rib/alpha-like repeat - - - - - - - - - - - - Gram_pos_anchor,Rib,YSIRK_signal CAFIFDFH_00316 405566.lhv_0978 2.85e-213 590.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F3RM@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N CAFIFDFH_00318 1033837.WANG_0179 1.75e-26 122.0 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal CAFIFDFH_00321 1033837.WANG_0179 1.14e-65 227.0 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal CAFIFDFH_00323 326425.lhe_1522 7.79e-56 178.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX CAFIFDFH_00326 891391.LAC30SC_02360 8.64e-56 186.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,3FCFA@33958|Lactobacillaceae 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 CAFIFDFH_00327 405566.lhv_0414 6.28e-99 297.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 CAFIFDFH_00328 748671.LCRIS_01642 1.18e-27 108.0 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,3F42G@33958|Lactobacillaceae 91061|Bacilli K rpiR family - - - - - - - - - - - - HTH_6,SIS CAFIFDFH_00329 891391.LAC30SC_02360 2.34e-57 190.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,3FCFA@33958|Lactobacillaceae 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 CAFIFDFH_00330 405566.lhv_0608 4.07e-54 182.0 29X5X@1|root,30IV1@2|Bacteria,1U48G@1239|Firmicutes,4I46R@91061|Bacilli,3F84J@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00331 1033837.WANG_1855 5.85e-167 476.0 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli,3F6CN@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 CAFIFDFH_00332 326425.lhe_0344 4.73e-286 784.0 COG2271@1|root,COG2271@2|Bacteria,1TS33@1239|Firmicutes,4HBVJ@91061|Bacilli,3F4E6@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator Superfamily - - - ko:K02445 - - - - ko00000,ko02000 2.A.1.4.3 - - MFS_1 CAFIFDFH_00333 326425.lhe_0345 8.37e-126 358.0 COG0431@1|root,COG0431@2|Bacteria,1VI8F@1239|Firmicutes,4HPT0@91061|Bacilli,3FCC2@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase azo1 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0052873,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.5.1.36,1.7.1.6 ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 - R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 - - - FMN_red CAFIFDFH_00334 326425.lhe_0346 5.21e-126 358.0 COG0431@1|root,COG0431@2|Bacteria,1TT2S@1239|Firmicutes,4HBQI@91061|Bacilli,3F544@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase azr - 1.5.1.36 ko:K22394 ko00740,ko01100,map00740,map01100 - R05705,R09748,R09750 RC00126 ko00000,ko00001,ko01000 - - - FMN_red CAFIFDFH_00335 405566.lhv_1870 7.79e-193 534.0 COG2365@1|root,COG2365@2|Bacteria,1VA24@1239|Firmicutes,4IQXZ@91061|Bacilli,3F4H4@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 CAFIFDFH_00336 326425.lhe_0348 3.16e-231 635.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HHVC@91061|Bacilli,3F3QR@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE CAFIFDFH_00337 326425.lhe_0349 1.28e-115 332.0 COG1286@1|root,COG1286@2|Bacteria,1U58E@1239|Firmicutes,4IEZI@91061|Bacilli,3F552@33958|Lactobacillaceae 91061|Bacilli S Colicin V production protein cvpA - - - - - - - - - - - Colicin_V CAFIFDFH_00338 326425.lhe_0350 9.37e-169 471.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,3F3ZX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB CAFIFDFH_00339 326425.lhe_0351 3.28e-193 536.0 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,3F4RU@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc CAFIFDFH_00340 326425.lhe_0352 1.43e-177 495.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,3F4AE@33958|Lactobacillaceae 91061|Bacilli D Sporulation initiation inhibitor soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 CAFIFDFH_00341 326425.lhe_0353 1.61e-196 546.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,3F47R@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc CAFIFDFH_00342 326425.lhe_0354 6.38e-59 181.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli,3F823@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF951) yyzM - - - - - - - - - - - DUF951 CAFIFDFH_00343 326425.lhe_0355 4.85e-257 705.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,3F3TK@33958|Lactobacillaceae 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C CAFIFDFH_00344 326425.lhe_0356 2.76e-177 494.0 COG4858@1|root,COG4858@2|Bacteria,1VF5N@1239|Firmicutes,4HH7B@91061|Bacilli,3F4JS@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1129) - - - - - - - - - - - - DUF1129 CAFIFDFH_00345 326425.lhe_0357 0.0 1048.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran CAFIFDFH_00346 326425.lhe_0358 0.0 1169.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter ndvA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran CAFIFDFH_00347 326425.lhe_0359 2.9e-157 441.0 COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,3F3Y0@33958|Lactobacillaceae 91061|Bacilli K response regulator vanR - - - - - - - - - - - Response_reg,Trans_reg_C CAFIFDFH_00348 326425.lhe_0360 5.13e-267 732.0 COG5002@1|root,COG5002@2|Bacteria,1TRZ0@1239|Firmicutes,4H9U1@91061|Bacilli,3FC2N@33958|Lactobacillaceae 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA CAFIFDFH_00349 326425.lhe_0361 0.0 1045.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,3F3UE@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 - R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M CAFIFDFH_00350 405566.lhv_1852 3.86e-186 516.0 COG1794@1|root,COG1794@2|Bacteria,1TQ6M@1239|Firmicutes,4HR12@91061|Bacilli,3FCEP@33958|Lactobacillaceae 91061|Bacilli M Belongs to the aspartate glutamate racemases family racD - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race CAFIFDFH_00351 1033837.WANG_1166 1.26e-104 316.0 COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,4HF7F@91061|Bacilli,3F57U@33958|Lactobacillaceae 91061|Bacilli S Archaea bacterial proteins of unknown function - - - ko:K06921 - - - - ko00000 - - - ATPase_2,DUF234 CAFIFDFH_00352 326425.lhe_0364 3.2e-21 85.9 29P5G@1|root,30A3N@2|Bacteria,1U65A@1239|Firmicutes,4IFV3@91061|Bacilli,3F737@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun CAFIFDFH_00353 405566.lhv_1850 2.01e-70 213.0 29P5G@1|root,30A3N@2|Bacteria,1U65A@1239|Firmicutes,4IFV3@91061|Bacilli,3F737@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun CAFIFDFH_00354 405566.lhv_1849 8.68e-46 147.0 COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,4HPRB@91061|Bacilli,3F802@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 CAFIFDFH_00355 326425.lhe_0366 8.68e-44 142.0 2AS5U@1|root,31HIR@2|Bacteria,1U6VJ@1239|Firmicutes,4IGPG@91061|Bacilli,3F8JX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00356 326425.lhe_0367 5.7e-36 122.0 2B46M@1|root,31WXN@2|Bacteria,1U6SR@1239|Firmicutes,4IGKA@91061|Bacilli,3F8F7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00359 405566.lhv_1846 8.47e-181 504.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli,3F3JB@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR CAFIFDFH_00360 405566.lhv_1845 4.4e-215 594.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,3F3SG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB CAFIFDFH_00361 405566.lhv_1151 5.29e-165 470.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F55P@33958|Lactobacillaceae 91061|Bacilli L transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon CAFIFDFH_00362 891391.LAC30SC_02360 2.34e-57 190.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,3FCFA@33958|Lactobacillaceae 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 CAFIFDFH_00363 1033837.WANG_1265 1.86e-51 173.0 COG0675@1|root,COG0675@2|Bacteria,1TQI8@1239|Firmicutes,4HI2X@91061|Bacilli,3F547@33958|Lactobacillaceae 91061|Bacilli L TIGRFAM transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - OrfB_IS605,OrfB_Zn_ribbon CAFIFDFH_00364 891391.LAC30SC_05415 4.44e-64 208.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,3FCFA@33958|Lactobacillaceae 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 CAFIFDFH_00365 40041.SZO_18960 3.78e-13 69.7 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,1M93B@119603|Streptococcus dysgalactiae group 91061|Bacilli V ABC transporter (Permease) - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CAFIFDFH_00366 405566.lhv_2093 5.18e-291 797.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,3F44D@33958|Lactobacillaceae 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease CAFIFDFH_00367 326425.lhe_1914 4.12e-47 151.0 29PJ2@1|root,30AH7@2|Bacteria,1U6NN@1239|Firmicutes,4IGFM@91061|Bacilli,3F87H@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00368 326425.lhe_1915 2.87e-101 293.0 COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,4HP8S@91061|Bacilli,3FBNQ@33958|Lactobacillaceae 91061|Bacilli K Penicillinase repressor atkY - - ko:K02171 ko01501,map01501 M00627 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Penicillinase_R CAFIFDFH_00369 326425.lhe_1916 8.46e-84 247.0 COG4633@1|root,COG4633@2|Bacteria,1TQ02@1239|Firmicutes,4IRVT@91061|Bacilli,3FBQA@33958|Lactobacillaceae 91061|Bacilli S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 CAFIFDFH_00370 326425.lhe_1917 1.81e-64 196.0 COG4633@1|root,COG4633@2|Bacteria,1U632@1239|Firmicutes,4IFSB@91061|Bacilli,3F6XB@33958|Lactobacillaceae 91061|Bacilli S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 CAFIFDFH_00371 405566.lhv_2097 0.0 1189.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,3F4IX@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase copA - 3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54 ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5,3.A.3.6 - - Cupredoxin_1,E1-E2_ATPase,Hydrolase CAFIFDFH_00372 1423748.BALB01000021_gene1650 1.33e-45 159.0 COG0477@1|root,COG0477@2|Bacteria,1UHPS@1239|Firmicutes,4HD28@91061|Bacilli,3FBSX@33958|Lactobacillaceae 91061|Bacilli EGP Sugar (and other) transporter - - - ko:K08368 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr CAFIFDFH_00373 1423748.BALB01000021_gene1650 1.06e-196 555.0 COG0477@1|root,COG0477@2|Bacteria,1UHPS@1239|Firmicutes,4HD28@91061|Bacilli,3FBSX@33958|Lactobacillaceae 91061|Bacilli EGP Sugar (and other) transporter - - - ko:K08368 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr CAFIFDFH_00374 1033837.WANG_1480 6.46e-27 98.2 29PGF@1|root,30AEK@2|Bacteria,1U6JH@1239|Firmicutes,4IGBZ@91061|Bacilli,3F819@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00375 326425.lhe_1921 7.04e-271 740.0 29NJT@1|root,309HR@2|Bacteria,1U547@1239|Firmicutes,4IEVJ@91061|Bacilli,3F4IW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00376 326425.lhe_1922 0.0 996.0 COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F3MU@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC CAFIFDFH_00377 326425.lhe_1923 0.0 947.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,3F3S8@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 CAFIFDFH_00378 326425.lhe_1924 0.0 1251.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,3F454@33958|Lactobacillaceae 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc CAFIFDFH_00379 405566.lhv_2104 0.0 884.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,3F3WA@33958|Lactobacillaceae 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N CAFIFDFH_00380 405566.lhv_2105 5.58e-191 532.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,3F3SD@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP CAFIFDFH_00381 326425.lhe_1927 1.31e-81 241.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,3F6GS@33958|Lactobacillaceae 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P CAFIFDFH_00382 1033837.WANG_1471 3.26e-23 88.6 COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,3F81W@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 CAFIFDFH_00383 326425.lhe_0001 0.0 898.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,3F3YA@33958|Lactobacillaceae 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N CAFIFDFH_00384 405566.lhv_0002 4.3e-256 704.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,3F3ZQ@33958|Lactobacillaceae 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 CAFIFDFH_00385 326425.lhe_0003 4.08e-47 150.0 COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,4HNMC@91061|Bacilli,3F803@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein YaaA yaaA - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 CAFIFDFH_00386 1423748.BALB01000029_gene1863 2.09e-267 732.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,3F3Q1@33958|Lactobacillaceae 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N CAFIFDFH_00387 405566.lhv_0005 0.0 1288.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,3F48M@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim CAFIFDFH_00388 326425.lhe_0006 0.0 1593.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,3F3YM@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV CAFIFDFH_00389 405566.lhv_0007 1.93e-65 199.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HP6B@91061|Bacilli,3FCDH@33958|Lactobacillaceae 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 CAFIFDFH_00390 326425.lhe_0008 2.06e-109 316.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,3F66N@33958|Lactobacillaceae 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB CAFIFDFH_00391 326425.lhe_0009 6.64e-45 145.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,3F7CY@33958|Lactobacillaceae 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 CAFIFDFH_00392 405566.lhv_0288 3.54e-166 464.0 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,3F3JY@33958|Lactobacillaceae 91061|Bacilli S (CBS) domain - - - - - - - - - - - - CBS CAFIFDFH_00393 326425.lhe_1813 2.81e-232 639.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F3RM@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N CAFIFDFH_00394 405566.lhv_0290 1.28e-132 375.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,3F3VZ@33958|Lactobacillaceae 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro CAFIFDFH_00395 326425.lhe_1811 0.0 2246.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,3F4KU@33958|Lactobacillaceae 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF CAFIFDFH_00396 326425.lhe_1810 1.26e-46 150.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,3F7JX@33958|Lactobacillaceae 91061|Bacilli J S4 domain protein yabO - - - - - - - - - - - S4 CAFIFDFH_00397 326425.lhe_1809 1.52e-77 231.0 COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli,3F76Z@33958|Lactobacillaceae 91061|Bacilli D Septum formation initiator divIC - - ko:K13052 - - - - ko00000,ko03036 - - - DivIC CAFIFDFH_00398 326425.lhe_1808 4.62e-81 240.0 COG1098@1|root,COG1098@2|Bacteria,1UI95@1239|Firmicutes,4ISGM@91061|Bacilli,3F6P8@33958|Lactobacillaceae 91061|Bacilli J S1 RNA binding domain - - - ko:K07571 - - - - ko00000 - - - S1 CAFIFDFH_00399 326425.lhe_1807 4.41e-309 841.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,3F4GY@33958|Lactobacillaceae 91061|Bacilli J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C CAFIFDFH_00400 326425.lhe_1806 0.0 1342.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,3F49Z@33958|Lactobacillaceae 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 CAFIFDFH_00401 326425.lhe_1805 1.53e-211 584.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,3F42B@33958|Lactobacillaceae 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 CAFIFDFH_00402 326425.lhe_1804 8.27e-250 685.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,3F4C6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus CAFIFDFH_00403 326425.lhe_1803 0.0 1035.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,3F439@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon CAFIFDFH_00405 326425.lhe_1801 1.77e-103 300.0 2APNN@1|root,31ES7@2|Bacteria,1V7W5@1239|Firmicutes,4HJDN@91061|Bacilli,3F70U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00408 326425.lhe_1798 7.84e-106 305.0 COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,3F6NT@33958|Lactobacillaceae 91061|Bacilli T GAF domain-containing protein ytsP - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 CAFIFDFH_00409 326425.lhe_1797 0.0 1553.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3F3RV@33958|Lactobacillaceae 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR CAFIFDFH_00410 326425.lhe_1796 0.0 2394.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,3F4ET@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 CAFIFDFH_00411 326425.lhe_1795 0.0 2412.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,3F3KF@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 CAFIFDFH_00412 1423748.BALB01000006_gene823 1.56e-116 335.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,3F3YX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase CAFIFDFH_00413 326425.lhe_0111 5.01e-276 757.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,3F45X@33958|Lactobacillaceae 91061|Bacilli O serine protease htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 CAFIFDFH_00414 405566.lhv_0099 8.73e-191 529.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,3F3S4@33958|Lactobacillaceae 91061|Bacilli S domain protein vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 CAFIFDFH_00415 326425.lhe_0109 1.83e-192 534.0 COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,3F3PV@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycI - - - - - - - - - - - YycI CAFIFDFH_00416 326425.lhe_0108 4e-314 857.0 COG4863@1|root,COG4863@2|Bacteria,1V32Y@1239|Firmicutes,4HG2Q@91061|Bacilli,3F4HR@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycH - - - - - - - - - - - YycH CAFIFDFH_00417 405566.lhv_0096 0.0 1151.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,3F45G@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 CAFIFDFH_00418 405566.lhv_0095 2.8e-169 473.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,3F4FB@33958|Lactobacillaceae 91061|Bacilli K response regulator yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C CAFIFDFH_00420 1423767.BALU01000010_gene388 4.3e-44 143.0 2930D@1|root,3270J@2|Bacteria,1USWD@1239|Firmicutes,4IG6X@91061|Bacilli,3F7S4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00423 405566.lhv_0092 3.45e-213 589.0 29V6Q@1|root,30B1T@2|Bacteria,1U7E0@1239|Firmicutes,4IH9W@91061|Bacilli,3F9G3@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP CAFIFDFH_00424 326425.lhe_0100 3.53e-171 478.0 2DKJ7@1|root,309P1@2|Bacteria,1U5EX@1239|Firmicutes,4IF6H@91061|Bacilli,3F5TG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - SLAP CAFIFDFH_00425 405566.lhv_0088 3.5e-254 699.0 29DXA@1|root,300V7@2|Bacteria,1U59E@1239|Firmicutes,4IF0P@91061|Bacilli,3F59A@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP CAFIFDFH_00426 525365.HMPREF0548_1861 2.67e-197 551.0 29NJD@1|root,309JD@2|Bacteria,1U580@1239|Firmicutes,4IEZA@91061|Bacilli,3F53B@33958|Lactobacillaceae 91061|Bacilli S Bacteriocin helveticin-J - - - - - - - - - - - - Helveticin_J CAFIFDFH_00427 1423748.BALB01000047_gene2059 2.24e-66 202.0 29P23@1|root,30A09@2|Bacteria,1U60S@1239|Firmicutes,4IFPI@91061|Bacilli,3F6ST@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00428 1423748.BALB01000047_gene2060 1.42e-81 241.0 COG1396@1|root,COG1396@2|Bacteria,1VEP9@1239|Firmicutes,4HPCR@91061|Bacilli,3F871@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_26,HTH_3 CAFIFDFH_00429 1423767.BALU01000019_gene1990 3.16e-102 295.0 COG2856@1|root,COG2856@2|Bacteria,1W1K0@1239|Firmicutes,4IGCD@91061|Bacilli,3F81Z@33958|Lactobacillaceae 91061|Bacilli E Zn peptidase - - - - - - - - - - - - Peptidase_M48,Peptidase_M78 CAFIFDFH_00430 891391.LAC30SC_00325 1.32e-146 414.0 29NRE@1|root,309PD@2|Bacteria,1U5FQ@1239|Firmicutes,4IF74@91061|Bacilli,3F5V7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00431 326425.lhe_0098 3.57e-188 521.0 COG0204@1|root,COG0204@2|Bacteria,1V9P5@1239|Firmicutes,4IPQB@91061|Bacilli,3F4RC@33958|Lactobacillaceae 91061|Bacilli I Acyl-transferase - - - - - - - - - - - - Acyltransferase CAFIFDFH_00432 326425.lhe_0097 2.49e-87 256.0 29NRE@1|root,309M2@2|Bacteria,1U5B0@1239|Firmicutes,4IF2D@91061|Bacilli,3F5ES@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00433 891391.LAC30SC_00315 8.43e-19 82.8 29NRE@1|root,309M2@2|Bacteria,1U5B0@1239|Firmicutes,4IF2D@91061|Bacilli,3F5ES@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00434 405566.lhv_0078 2.05e-112 327.0 29NJE@1|root,30GYN@2|Bacteria,1UGVU@1239|Firmicutes,4IF93@91061|Bacilli,3F60Q@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 CAFIFDFH_00435 405566.lhv_0078 1.46e-53 174.0 29NJE@1|root,30GYN@2|Bacteria,1UGVU@1239|Firmicutes,4IF93@91061|Bacilli,3F60Q@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 CAFIFDFH_00436 326425.lhe_0094 7.53e-203 561.0 COG1442@1|root,COG1442@2|Bacteria,1UY4M@1239|Firmicutes,4IEY6@91061|Bacilli,3F4YZ@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 8 arbx - - - - - - - - - - - Glyco_transf_8 CAFIFDFH_00437 405566.lhv_0076 3.73e-239 656.0 COG1442@1|root,COG1442@2|Bacteria,1VGDI@1239|Firmicutes,4I0ZW@91061|Bacilli,3FCDT@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 CAFIFDFH_00438 525365.HMPREF0548_1834 3.41e-13 68.2 COG1442@1|root,COG1442@2|Bacteria,1VGDI@1239|Firmicutes,4IPQC@91061|Bacilli,3FBE4@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 CAFIFDFH_00439 405566.lhv_0075 2.17e-205 567.0 COG1442@1|root,COG1442@2|Bacteria,1VGDI@1239|Firmicutes,4IPQC@91061|Bacilli,3FBE4@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 CAFIFDFH_00440 326425.lhe_0091 1.6e-214 591.0 COG0204@1|root,COG0204@2|Bacteria,1V2F4@1239|Firmicutes,4IF2T@91061|Bacilli,3F5FU@33958|Lactobacillaceae 91061|Bacilli I Phosphate acyltransferases arbZ - - - - - - - - - - - Acyltransferase CAFIFDFH_00441 405566.lhv_2203 5.04e-47 150.0 COG4892@1|root,COG4892@2|Bacteria,1V64Y@1239|Firmicutes 1239|Firmicutes S Cytochrome b5 - - - - - - - - - - - - Cyt-b5 CAFIFDFH_00442 405566.lhv_0073 2.72e-137 390.0 COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HFSV@91061|Bacilli,3F48I@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate CAFIFDFH_00443 1423748.BALB01000037_gene1992 1.48e-10 60.8 COG0583@1|root,COG0583@2|Bacteria,1V3HS@1239|Firmicutes,4IQPW@91061|Bacilli,3F4HP@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CAFIFDFH_00444 1423748.BALB01000037_gene1992 2.82e-80 245.0 COG0583@1|root,COG0583@2|Bacteria,1V3HS@1239|Firmicutes,4IQPW@91061|Bacilli,3F4HP@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CAFIFDFH_00445 1423748.BALB01000037_gene1992 2.32e-51 170.0 COG0583@1|root,COG0583@2|Bacteria,1V3HS@1239|Firmicutes,4IQPW@91061|Bacilli,3F4HP@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CAFIFDFH_00446 405566.lhv_0516 7.81e-08 52.8 COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,3F4M8@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DUF772 CAFIFDFH_00447 326425.lhe_0465 8.83e-204 563.0 COG0846@1|root,COG0846@2|Bacteria,1V192@1239|Firmicutes,4IQTP@91061|Bacilli,3F52D@33958|Lactobacillaceae 91061|Bacilli K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - - - - - - - - - - SIR2 CAFIFDFH_00448 405566.lhv_1753 9.23e-219 604.0 COG2176@1|root,COG2176@2|Bacteria,1TRS5@1239|Firmicutes,4HFJA@91061|Bacilli,3F546@33958|Lactobacillaceae 91061|Bacilli L EXOIII - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - BRCT,RNase_T CAFIFDFH_00449 326425.lhe_0467 6.94e-202 559.0 COG2169@1|root,COG2169@2|Bacteria,1V4X2@1239|Firmicutes,4HIF5@91061|Bacilli,3F3Y8@33958|Lactobacillaceae 91061|Bacilli F DNA RNA non-specific endonuclease endA - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 CAFIFDFH_00450 326425.lhe_0468 0.0 967.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD1 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 CAFIFDFH_00451 326425.lhe_0469 1.15e-257 706.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HBKK@91061|Bacilli,3FC3J@33958|Lactobacillaceae 91061|Bacilli P ATPases associated with a variety of cellular activities malK - - ko:K10112,ko:K17240 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00599,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.38 - - ABC_tran,TOBE_2 CAFIFDFH_00452 405566.lhv_1749 1.4e-203 563.0 COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,4HCD0@91061|Bacilli,3F464@33958|Lactobacillaceae 91061|Bacilli P ABC-type sugar transport systems, permease components - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 CAFIFDFH_00453 326425.lhe_0471 1.96e-187 521.0 COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,4HBK1@91061|Bacilli,3FC8G@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 CAFIFDFH_00454 405566.lhv_1747 0.0 874.0 COG0595@1|root,COG0595@2|Bacteria,1UDEF@1239|Firmicutes,4HIN2@91061|Bacilli,3F4WJ@33958|Lactobacillaceae 91061|Bacilli S Zn-dependent metallo-hydrolase RNA specificity domain - - - - - - - - - - - - Lactamase_B_2,RMMBL CAFIFDFH_00455 326425.lhe_0473 1.43e-308 841.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HEKH@91061|Bacilli,3F4P5@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 CAFIFDFH_00456 405566.lhv_1744 2.02e-216 597.0 COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,4HAPC@91061|Bacilli,3FCA3@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein corA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - iYO844.BSU08000 CorA CAFIFDFH_00457 326425.lhe_0475 1.97e-208 578.0 COG2367@1|root,COG2367@2|Bacteria,1U564@1239|Firmicutes,4IEXG@91061|Bacilli,3F4WE@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 CAFIFDFH_00458 326425.lhe_0476 2.86e-127 362.0 COG1309@1|root,COG1309@2|Bacteria,1V1DM@1239|Firmicutes,4HG0Y@91061|Bacilli,3F5CS@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family yobS GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N,WHG CAFIFDFH_00459 326425.lhe_0477 0.0 1451.0 COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4HBM6@91061|Bacilli,3FCCY@33958|Lactobacillaceae 91061|Bacilli S MMPL family ydgH - - ko:K06994 - - - - ko00000 - - - MMPL CAFIFDFH_00460 326425.lhe_0478 6.3e-203 566.0 29NMZ@1|root,309JX@2|Bacteria,1U58Z@1239|Firmicutes,4IF0A@91061|Bacilli,3F573@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - zf-ribbon_3 CAFIFDFH_00461 326425.lhe_0479 0.0 903.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CAFIFDFH_00462 326425.lhe_0480 4.14e-164 459.0 COG1396@1|root,COG1396@2|Bacteria,1VBK2@1239|Firmicutes,4HCZ9@91061|Bacilli,3FBE7@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix plcR - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,TPR_12,TPR_8 CAFIFDFH_00463 1423748.BALB01000026_gene1812 1e-09 58.2 COG1396@1|root,COG1396@2|Bacteria,1VBK2@1239|Firmicutes,4HCZ9@91061|Bacilli,3FBE7@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix plcR - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,TPR_12,TPR_8 CAFIFDFH_00464 405566.lhv_1737 7.24e-199 550.0 COG0657@1|root,COG0657@2|Bacteria,1VEC5@1239|Firmicutes,4HKY6@91061|Bacilli,3F50A@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 CAFIFDFH_00465 405566.lhv_1736 4.04e-142 401.0 COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,4HIU5@91061|Bacilli,3F3SV@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc CAFIFDFH_00466 405566.lhv_1735 4.81e-127 361.0 COG1670@1|root,COG1670@2|Bacteria,1V49W@1239|Firmicutes,4HHAP@91061|Bacilli,3F5A6@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain yjcK - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 CAFIFDFH_00467 326425.lhe_0484 0.0 867.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,3F3M6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b CAFIFDFH_00468 525365.HMPREF0548_1798 5.55e-30 114.0 COG3405@1|root,COG3405@2|Bacteria,1VCBY@1239|Firmicutes,4HTF0@91061|Bacilli,3F595@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 8 - - - - - - - - - - - - Glyco_hydro_8 CAFIFDFH_00469 1423767.BALU01000010_gene363 5.67e-84 251.0 COG3405@1|root,COG3405@2|Bacteria,1VCBY@1239|Firmicutes,4HTF0@91061|Bacilli,3F595@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 8 - - - - - - - - - - - - Glyco_hydro_8 CAFIFDFH_00470 1033837.WANG_1234 2.16e-25 100.0 COG3212@1|root,COG3212@2|Bacteria,1VEU1@1239|Firmicutes,4HPJK@91061|Bacilli,3F6RU@33958|Lactobacillaceae 91061|Bacilli S Peptidase propeptide and YPEB domain ykoJ - - - - - - - - - - - PepSY CAFIFDFH_00472 405566.lhv_0120 6.43e-159 444.0 COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,4HA8H@91061|Bacilli,3F4RZ@33958|Lactobacillaceae 91061|Bacilli S HD containing hydrolase-like enzyme yfbR - - ko:K07023 - - - - ko00000 - - - HD_2 CAFIFDFH_00473 326425.lhe_0130 2.34e-204 565.0 COG1403@1|root,COG1403@2|Bacteria,1V4V2@1239|Firmicutes,4HI4X@91061|Bacilli,3F4P0@33958|Lactobacillaceae 91061|Bacilli L HNH nucleases - - - - - - - - - - - - HNH,HNH_5 CAFIFDFH_00474 326425.lhe_0131 2.21e-177 494.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - - ko:K17076 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.20 - - ABC_tran CAFIFDFH_00475 326425.lhe_0132 0.0 1030.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease XK27_05795 - - ko:K17073,ko:K17074 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.20 - - BPD_transp_1,SBP_bac_3 CAFIFDFH_00476 326425.lhe_0133 6.21e-159 444.0 COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HG5E@91061|Bacilli,3F59D@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA glycosylase MPG family yxlJ GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco CAFIFDFH_00477 326425.lhe_0134 1.61e-81 241.0 COG3189@1|root,COG3189@2|Bacteria,1VABH@1239|Firmicutes,4HKI2@91061|Bacilli,3F715@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function, DUF488 yeaO - - - - - - - - - - - DUF488 CAFIFDFH_00478 405566.lhv_0126 3.66e-161 454.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,3FB68@33958|Lactobacillaceae 91061|Bacilli P Integral membrane protein TerC family terC - - - - - - - - - - - TerC CAFIFDFH_00479 326425.lhe_0136 6.44e-122 347.0 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,3F4TG@33958|Lactobacillaceae 91061|Bacilli L 6-O-methylguanine DNA methyltransferase, DNA binding domain adaB GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,Methyltransf_1N CAFIFDFH_00480 405566.lhv_0128 1.45e-169 473.0 COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HC4I@91061|Bacilli,3F4WS@33958|Lactobacillaceae 91061|Bacilli K SIR2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 CAFIFDFH_00481 405566.lhv_0129 1.14e-111 320.0 2CCJZ@1|root,303JM@2|Bacteria,1U58T@1239|Firmicutes,4IF00@91061|Bacilli,3F565@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00482 405566.lhv_0130 0.0 980.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N CAFIFDFH_00483 326425.lhe_0140 1.97e-229 630.0 COG4814@1|root,COG4814@2|Bacteria,1UY1T@1239|Firmicutes,4I2Y3@91061|Bacilli,3F5D8@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 CAFIFDFH_00484 326425.lhe_0141 8.42e-187 518.0 COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1V4A0@1239|Firmicutes,4HHJ9@91061|Bacilli,3F3RG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - Cauli_VI,RNase_H CAFIFDFH_00485 326425.lhe_0142 1.04e-186 523.0 COG4086@1|root,COG4086@2|Bacteria,1UY79@1239|Firmicutes,4HAZ5@91061|Bacilli,3F416@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1002) - - - - - - - - - - - - DUF1002 CAFIFDFH_00486 326425.lhe_0143 5.32e-204 563.0 COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HNAP@91061|Bacilli,3F52I@33958|Lactobacillaceae 91061|Bacilli S glycosyl transferase family 2 epsV - - - - - - - - - - - Glycos_transf_2 CAFIFDFH_00487 326425.lhe_0144 2.62e-164 458.0 COG0596@1|root,COG0596@2|Bacteria,1TSFW@1239|Firmicutes,4HI0M@91061|Bacilli,3F5BW@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 CAFIFDFH_00488 326425.lhe_0145 1.2e-148 418.0 COG0702@1|root,COG0702@2|Bacteria,1UJSC@1239|Firmicutes,4HCVT@91061|Bacilli,3F4ZZ@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 CAFIFDFH_00489 326425.lhe_0146 6.78e-85 251.0 29PF3@1|root,30AD9@2|Bacteria,1U6HK@1239|Firmicutes,4IG9W@91061|Bacilli,3F7XT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00490 326425.lhe_0147 1.69e-231 637.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3V8@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs2 - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N CAFIFDFH_00491 405566.lhv_0138 4.46e-156 438.0 COG1309@1|root,COG1309@2|Bacteria,1VZKY@1239|Firmicutes,4HM1C@91061|Bacilli,3F43G@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CAFIFDFH_00492 326425.lhe_0149 1.97e-171 481.0 2CCK0@1|root,309GI@2|Bacteria,1U516@1239|Firmicutes,4IESZ@91061|Bacilli,3F3YE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00493 326425.lhe_0150 0.0 909.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnPH2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1,SBP_bac_3 CAFIFDFH_00494 326425.lhe_0151 5.22e-173 483.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran CAFIFDFH_00495 326425.lhe_0152 4.54e-283 775.0 COG2340@1|root,COG2340@2|Bacteria,1V1IM@1239|Firmicutes,4HRX1@91061|Bacilli,3F3QG@33958|Lactobacillaceae 91061|Bacilli S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP,SLH CAFIFDFH_00496 326425.lhe_0153 1.03e-264 724.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,3F41Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N CAFIFDFH_00497 405566.lhv_0144 5.96e-143 407.0 2EIZT@1|root,33CQY@2|Bacteria,1VN62@1239|Firmicutes,4HRPP@91061|Bacilli,3F5GU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - MerR_1 CAFIFDFH_00498 405566.lhv_0145 5.65e-257 706.0 COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,4HCP3@91061|Bacilli,3F3M9@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibE - - - - - - - - - - - YibE_F CAFIFDFH_00499 326425.lhe_0156 4.71e-168 471.0 COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,4HBKX@91061|Bacilli,3F3S6@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibF - - - - - - - - - - - YibE_F CAFIFDFH_00500 326425.lhe_0157 6.21e-204 563.0 COG0657@1|root,COG0657@2|Bacteria,1V212@1239|Firmicutes,4HGWT@91061|Bacilli,3FBE2@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 CAFIFDFH_00501 1423748.BALB01000006_gene770 3.08e-43 140.0 2DKRT@1|root,30AIP@2|Bacteria,1U6R2@1239|Firmicutes,4IGIC@91061|Bacilli,3F8CA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00502 326425.lhe_0159 0.0 2031.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HEJM@91061|Bacilli,3FC1B@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 31 family - - - - - - - - - - - - DUF5110,F5_F8_type_C,Glyco_hydro_31 CAFIFDFH_00503 405566.lhv_0153 8.67e-111 318.0 COG3613@1|root,COG3613@2|Bacteria,1VY4Q@1239|Firmicutes,4HXB4@91061|Bacilli,3F5CB@33958|Lactobacillaceae 91061|Bacilli F Nucleoside ntd - 2.4.2.6 ko:K08728 ko00240,map00240 - R02806 RC00063 ko00000,ko00001,ko01000 - - - Nuc_deoxyrib_tr CAFIFDFH_00504 405566.lhv_0154 5.57e-115 329.0 COG1762@1|root,COG1762@2|Bacteria,1V8H9@1239|Firmicutes,4HK36@91061|Bacilli,3F4A7@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.200,2.7.1.204 ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279,M00807 R05570,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5,4.A.5.1 - - PTS_EIIA_2 CAFIFDFH_00505 326425.lhe_0162 1.69e-189 526.0 COG2365@1|root,COG2365@2|Bacteria,1V851@1239|Firmicutes,4HJB2@91061|Bacilli,3F55V@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 CAFIFDFH_00506 326425.lhe_0163 6.8e-115 329.0 COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,4HNHG@91061|Bacilli,3F4Z0@33958|Lactobacillaceae 91061|Bacilli T universal stress protein usp5 - - - - - - - - - - - Usp CAFIFDFH_00507 326425.lhe_0164 2.28e-200 557.0 COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,3F3KK@33958|Lactobacillaceae 91061|Bacilli P Phosphonate ABC transporter phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd CAFIFDFH_00508 326425.lhe_0165 6.34e-180 501.0 COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,4HC3N@91061|Bacilli,3F3SJ@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC GO:0006810,GO:0008150,GO:0015716,GO:0051179,GO:0051234,GO:0071702 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran CAFIFDFH_00509 326425.lhe_0166 3.86e-169 474.0 COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,4HBT8@91061|Bacilli,3F58M@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component phnB - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 CAFIFDFH_00510 326425.lhe_0167 2.22e-191 531.0 COG3639@1|root,COG3639@2|Bacteria,1V15B@1239|Firmicutes,4IQWU@91061|Bacilli,3F4TN@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 CAFIFDFH_00511 405566.lhv_0161 3.65e-139 392.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,3F5KA@33958|Lactobacillaceae 91061|Bacilli L glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco CAFIFDFH_00512 326425.lhe_0169 1.05e-108 313.0 2CCK1@1|root,309S4@2|Bacteria,1U5KG@1239|Firmicutes,4IFBA@91061|Bacilli,3F64Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00513 405566.lhv_0163 0.0 947.0 2EQYH@1|root,33II5@2|Bacteria,1VMH1@1239|Firmicutes,4HUIK@91061|Bacilli,3F5E7@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos CAFIFDFH_00514 326425.lhe_0171 0.0 1323.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HA44@91061|Bacilli,3FB65@33958|Lactobacillaceae 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 CAFIFDFH_00515 326425.lhe_0172 0.0 885.0 COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,4HAB0@91061|Bacilli,3F3S7@33958|Lactobacillaceae 91061|Bacilli S ATP-grasp enzyme yxbA - 6.3.1.12 ko:K17810 - - - - ko00000,ko01000 - - - CPSase_L_D2,Dala_Dala_lig_C CAFIFDFH_00518 326425.lhe_0174 0.0 1543.0 COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,4HBIY@91061|Bacilli,3F435@33958|Lactobacillaceae 91061|Bacilli F Ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD CAFIFDFH_00519 326425.lhe_0175 1.35e-180 501.0 COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HGJ9@91061|Bacilli,3F46H@33958|Lactobacillaceae 91061|Bacilli O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM CAFIFDFH_00520 326425.lhe_0176 4.58e-128 364.0 COG2151@1|root,COG2461@1|root,COG2151@2|Bacteria,COG2461@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,3F7D5@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein yitW - - - - - - - - - - - DUF1858,FeS_assembly_P CAFIFDFH_00521 326425.lhe_0177 7.07e-293 798.0 COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli,3F45M@33958|Lactobacillaceae 91061|Bacilli S PAS domain XK27_04775 - - ko:K09155 - - - - ko00000 - - - DUF438,Hemerythrin,PAS_10 CAFIFDFH_00522 405566.lhv_0173 7.66e-292 796.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,3F4F9@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator yttB - - - - - - - - - - - MFS_1 CAFIFDFH_00523 326425.lhe_0179 0.0 1302.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F4CX@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N CAFIFDFH_00524 405566.lhv_0176 0.0 1302.0 COG3158@1|root,COG3158@2|Bacteria,1TRUQ@1239|Firmicutes,4HA8Z@91061|Bacilli,3F4CU@33958|Lactobacillaceae 91061|Bacilli P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans CAFIFDFH_00525 405566.lhv_0177 1.13e-97 284.0 29NU4@1|root,309S8@2|Bacteria,1U5KK@1239|Firmicutes,4IFBH@91061|Bacilli,3F65J@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00526 405566.lhv_0181 5.5e-16 77.0 2AR9J@1|root,31GJF@2|Bacteria,1U6R9@1239|Firmicutes,4IGIM@91061|Bacilli,3F8CR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00527 405566.lhv_0182 2.09e-41 136.0 2AQKB@1|root,31FT9@2|Bacteria,1U6IH@1239|Firmicutes,4IGAU@91061|Bacilli,3F7ZB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00528 1033837.WANG_1801 3.28e-211 597.0 2DHS4@1|root,300QQ@2|Bacteria,1U572@1239|Firmicutes,4IEYM@91061|Bacilli,3F4ZW@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP CAFIFDFH_00530 257314.LJ_1020 4.39e-12 64.7 COG1595@1|root,COG1595@2|Bacteria,1U6KG@1239|Firmicutes,4IGD9@91061|Bacilli,3F83H@33958|Lactobacillaceae 91061|Bacilli K DNA-templated transcription, initiation - - - - - - - - - - - - Sigma70_r4 CAFIFDFH_00531 748671.LCRIS_00174 1.89e-35 125.0 COG1595@1|root,COG1595@2|Bacteria,1U6KG@1239|Firmicutes,4IGD9@91061|Bacilli,3F83H@33958|Lactobacillaceae 91061|Bacilli K DNA-templated transcription, initiation - - - - - - - - - - - - Sigma70_r4 CAFIFDFH_00532 405566.lhv_0190 2.75e-286 783.0 COG1705@1|root,COG1705@2|Bacteria,1TVPT@1239|Firmicutes,4HC0X@91061|Bacilli,3F4I7@33958|Lactobacillaceae 91061|Bacilli NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - - - - - - - - - - Glucosaminidase,SLAP CAFIFDFH_00533 326425.lhe_0190 9.56e-267 729.0 COG5632@1|root,COG5632@2|Bacteria,1V3MY@1239|Firmicutes,4HBWG@91061|Bacilli,3F4BU@33958|Lactobacillaceae 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase - - 3.2.1.96,3.5.1.28 ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 - R04112 RC00064,RC00141 ko00000,ko00001,ko01000 - GH73 - Amidase_2,Glucosaminidase,SH3_8,SLAP CAFIFDFH_00534 405566.lhv_0192 0.0 1124.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,4H9Q5@91061|Bacilli,3F4AZ@33958|Lactobacillaceae 91061|Bacilli P TrkA C-terminal domain protein yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N CAFIFDFH_00535 405566.lhv_0193 8.6e-171 478.0 COG2944@1|root,COG3600@1|root,COG2944@2|Bacteria,COG3600@2|Bacteria,1UK2I@1239|Firmicutes,4ITGB@91061|Bacilli,3F4EH@33958|Lactobacillaceae 91061|Bacilli K Protein of unknown function (DUF4065) - - - - - - - - - - - - DUF4065,HTH_3 CAFIFDFH_00536 405566.lhv_0195 1.9e-229 632.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HV6B@91061|Bacilli,3FCE9@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CAFIFDFH_00537 405566.lhv_0196 1.1e-155 437.0 29NPN@1|root,309MJ@2|Bacteria,1U5C8@1239|Firmicutes,4IF3G@91061|Bacilli,3F5HZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00538 405566.lhv_0512 1.21e-16 78.6 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli,3F6CN@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 CAFIFDFH_00539 405566.lhv_1515 7.59e-247 679.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,3F3MZ@33958|Lactobacillaceae 91061|Bacilli S ABC transporter substrate-binding protein PnrA-like tcsA - - ko:K02058,ko:K07335 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp CAFIFDFH_00540 326425.lhe_1419 0.0 979.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,3F50N@33958|Lactobacillaceae 91061|Bacilli S ABC transporter mglA - 3.6.3.17 ko:K02056,ko:K06400 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran CAFIFDFH_00541 326425.lhe_1420 9.63e-270 739.0 COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli,3F59X@33958|Lactobacillaceae 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family mglC - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 CAFIFDFH_00542 326425.lhe_1421 1.48e-220 609.0 COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli,3F4AJ@33958|Lactobacillaceae 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufQ - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 CAFIFDFH_00543 405566.lhv_1519 1.67e-186 520.0 COG1737@1|root,COG1737@2|Bacteria,1UYAM@1239|Firmicutes,4HVUK@91061|Bacilli,3FC4F@33958|Lactobacillaceae 91061|Bacilli K SIS domain - - - - - - - - - - - - HTH_6,SIS CAFIFDFH_00544 326425.lhe_1423 2.66e-310 844.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,3F4Z8@33958|Lactobacillaceae 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N CAFIFDFH_00545 326425.lhe_1424 0.0 1402.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,3F4FD@33958|Lactobacillaceae 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS CAFIFDFH_00546 326425.lhe_1425 4.12e-254 696.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,3F4RT@33958|Lactobacillaceae 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C CAFIFDFH_00547 326425.lhe_1426 0.0 949.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,3F3U7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran CAFIFDFH_00548 326425.lhe_1427 0.0 1489.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,3F4IQ@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C CAFIFDFH_00549 326425.lhe_1428 4.51e-163 456.0 COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,3F48D@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 CAFIFDFH_00550 1033837.WANG_1540 1.01e-51 163.0 COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,3F81F@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU06460 PurS CAFIFDFH_00551 405566.lhv_1532 2.92e-171 478.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli,3F44Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt CAFIFDFH_00552 326425.lhe_1431 4.64e-277 757.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,3F3YV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp CAFIFDFH_00553 1033837.WANG_1537 4.1e-111 319.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,3F6P0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC CAFIFDFH_00554 326425.lhe_1433 0.0 1094.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,3F3U6@33958|Lactobacillaceae 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS CAFIFDFH_00555 326425.lhe_1434 1.33e-174 487.0 COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,4HDMG@91061|Bacilli,3F4TX@33958|Lactobacillaceae 91061|Bacilli E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate aroD - 4.2.1.10 ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I CAFIFDFH_00556 326425.lhe_1435 2.23e-102 305.0 COG2271@1|root,COG2271@2|Bacteria,1UI3V@1239|Firmicutes,4ISEV@91061|Bacilli,3F3ZF@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CAFIFDFH_00557 326425.lhe_1436 9.93e-198 550.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,3F4WM@33958|Lactobacillaceae 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N CAFIFDFH_00558 326425.lhe_1746 1.22e-139 394.0 COG0693@1|root,COG0693@2|Bacteria,1V3UV@1239|Firmicutes,4IQYM@91061|Bacilli,3F3T7@33958|Lactobacillaceae 91061|Bacilli S DJ-1/PfpI family - - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI CAFIFDFH_00559 405566.lhv_0347 6.45e-91 266.0 COG3152@1|root,COG3152@2|Bacteria,1VDSW@1239|Firmicutes,4HMMJ@91061|Bacilli,3F4C0@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF805) yhaH - - - - - - - - - - - DUF805 CAFIFDFH_00560 1423748.BALB01000002_gene295 1.01e-87 258.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,3F656@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 CAFIFDFH_00561 326425.lhe_1758 2.27e-103 298.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,3F696@33958|Lactobacillaceae 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 CAFIFDFH_00562 405566.lhv_0342 3.86e-193 535.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,3F4KC@33958|Lactobacillaceae 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 CAFIFDFH_00563 405566.lhv_0341 3.84e-181 505.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,3F3UW@33958|Lactobacillaceae 91061|Bacilli U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ CAFIFDFH_00564 326425.lhe_1761 1.58e-194 540.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,3F48E@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran CAFIFDFH_00565 326425.lhe_1762 1.19e-198 551.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,3F3VD@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran CAFIFDFH_00566 1423748.BALB01000002_gene302 3.16e-80 238.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli,3F6GJ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 CAFIFDFH_00567 326425.lhe_1764 1.04e-217 601.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,3F3W6@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L CAFIFDFH_00568 1033837.WANG_0019 3.82e-82 243.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,3F67D@33958|Lactobacillaceae 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 CAFIFDFH_00569 1423748.BALB01000002_gene305 1.46e-73 221.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,3F6GN@33958|Lactobacillaceae 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 CAFIFDFH_00570 1423748.BALB01000002_gene306 3.15e-20 80.5 COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4HR2X@91061|Bacilli,3F8TC@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 CAFIFDFH_00571 1293597.BN147_06990 3.13e-46 148.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,3F7CW@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a CAFIFDFH_00572 405566.lhv_0333 2.61e-155 436.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,3F3KB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid CAFIFDFH_00573 326425.lhe_1769 5.1e-301 822.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,3F4FV@33958|Lactobacillaceae 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY CAFIFDFH_00574 1423748.BALB01000002_gene310 1.73e-93 273.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,3F675@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A CAFIFDFH_00575 326425.lhe_1771 2.22e-34 117.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli,3F7ZU@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 CAFIFDFH_00576 1423748.BALB01000002_gene312 2.63e-110 318.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,3F3VY@33958|Lactobacillaceae 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C CAFIFDFH_00577 326425.lhe_1773 5.21e-73 219.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,3F6KN@33958|Lactobacillaceae 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p CAFIFDFH_00578 326425.lhe_1774 5.05e-121 345.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,3F4G5@33958|Lactobacillaceae 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 CAFIFDFH_00579 1423748.BALB01000002_gene315 2.28e-89 262.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,3F64E@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 CAFIFDFH_00580 1423748.BALB01000002_gene316 1e-39 131.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli,3FB5M@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 CAFIFDFH_00581 326425.lhe_1777 3.53e-123 351.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,3F3Q7@33958|Lactobacillaceae 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C CAFIFDFH_00582 1423748.BALB01000002_gene318 6.92e-45 145.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,3F6X5@33958|Lactobacillaceae 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 CAFIFDFH_00583 326425.lhe_1779 2.55e-79 236.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli,3F6GT@33958|Lactobacillaceae 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 CAFIFDFH_00584 326425.lhe_1780 6.37e-55 171.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,3F7FX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 CAFIFDFH_00585 405566.lhv_0320 1.45e-34 118.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,3F82Z@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 CAFIFDFH_00586 1423748.BALB01000002_gene322 1.66e-100 291.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,3F653@33958|Lactobacillaceae 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 CAFIFDFH_00587 326425.lhe_1783 6.12e-157 440.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,3F3Q8@33958|Lactobacillaceae 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C CAFIFDFH_00588 1423767.BALU01000004_gene1270 9.07e-73 219.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,3F6K6@33958|Lactobacillaceae 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 CAFIFDFH_00589 326425.lhe_1785 4.33e-62 190.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,3F6XP@33958|Lactobacillaceae 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 CAFIFDFH_00590 326425.lhe_1786 5.7e-198 548.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,3F3XI@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C CAFIFDFH_00591 326425.lhe_1787 4.67e-63 193.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli,3F6Z2@33958|Lactobacillaceae 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 CAFIFDFH_00592 326425.lhe_1788 3.85e-137 389.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,3F3QD@33958|Lactobacillaceae 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 CAFIFDFH_00593 1423748.BALB01000002_gene329 3.29e-146 412.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli,3F45I@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 CAFIFDFH_00594 1033837.WANG_1903 6.34e-66 200.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,3F6KC@33958|Lactobacillaceae 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 CAFIFDFH_00595 326425.lhe_1791 0.0 1367.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,3F3JR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 CAFIFDFH_00596 326425.lhe_1792 1.39e-106 307.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,3F3RX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 CAFIFDFH_00597 405566.lhv_0308 7.28e-92 268.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli,3F64B@33958|Lactobacillaceae 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 CAFIFDFH_00598 326425.lhe_1794 1.69e-156 440.0 COG1989@1|root,COG1989@2|Bacteria,1W118@1239|Firmicutes,4HZ6B@91061|Bacilli,3F863@33958|Lactobacillaceae 91061|Bacilli NOU Bacterial Peptidase A24 N-terminal domain comC - 3.4.23.43 ko:K02236 - M00429 - - ko00000,ko00002,ko01000,ko02044 - - - DiS_P_DiS,Peptidase_A24 CAFIFDFH_00599 405566.lhv_0563 0.0 880.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F41R@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_2 - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr CAFIFDFH_00600 405566.lhv_0562 5.45e-312 852.0 COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,4HA18@91061|Bacilli,3F3VX@33958|Lactobacillaceae 91061|Bacilli C Na H antiporter NhaC nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter CAFIFDFH_00601 1033837.WANG_1131 3.08e-64 197.0 2BQGU@1|root,32JC9@2|Bacteria,1UQJZ@1239|Firmicutes,4IFJT@91061|Bacilli,3F6M4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00602 1033837.WANG_1132 7.31e-154 433.0 COG0670@1|root,COG0670@2|Bacteria,1V779@1239|Firmicutes,4HIX1@91061|Bacilli,3F3QH@33958|Lactobacillaceae 91061|Bacilli S Belongs to the BI1 family ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I CAFIFDFH_00603 1033837.WANG_1133 1.12e-146 415.0 COG3548@1|root,COG3548@2|Bacteria,1VNI3@1239|Firmicutes,4HSHZ@91061|Bacilli,3F5J9@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) ybbB - - - - - - - - - - - DUF1211 CAFIFDFH_00604 326425.lhe_0552 3.23e-218 602.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,3F447@33958|Lactobacillaceae 91061|Bacilli G Lipid kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat CAFIFDFH_00605 326425.lhe_0551 0.0 957.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,3F44H@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey CAFIFDFH_00606 326425.lhe_0550 0.0 934.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,3F4BK@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase CAFIFDFH_00607 405566.lhv_0553 2.94e-66 201.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,3F7XB@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln CAFIFDFH_00608 326425.lhe_0548 3.77e-269 737.0 COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,3F3KI@33958|Lactobacillaceae 91061|Bacilli S sex pheromone camS - - - - - - - - - - - CamS CAFIFDFH_00609 326425.lhe_0547 0.0 1312.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,3F43C@33958|Lactobacillaceae 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 CAFIFDFH_00610 405566.lhv_0550 0.0 1463.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3F400@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C CAFIFDFH_00611 326425.lhe_0545 1.18e-142 403.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIY4@91061|Bacilli,3F584@33958|Lactobacillaceae 91061|Bacilli NU mannosyl-glycoprotein acmA - 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,SH3_8,YceG CAFIFDFH_00613 326425.lhe_0543 8.06e-115 328.0 COG3091@1|root,COG3091@2|Bacteria,1V6NU@1239|Firmicutes,4HIHY@91061|Bacilli,3F703@33958|Lactobacillaceae 91061|Bacilli S Belongs to the SprT family ydcK - - ko:K03095 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT CAFIFDFH_00614 326425.lhe_0542 4.18e-177 492.0 COG3774@1|root,COG3774@2|Bacteria,1V9J7@1239|Firmicutes,4HIAM@91061|Bacilli,3F4U2@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase sugar-binding region containing DXD motif - - - - - - - - - - - - Caps_synth,Gly_transf_sug CAFIFDFH_00615 326425.lhe_0541 0.0 907.0 COG2244@1|root,COG2244@2|Bacteria,1TRTX@1239|Firmicutes,4HDWM@91061|Bacilli,3FB7P@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein epsU - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C CAFIFDFH_00616 405566.lhv_0546 3.66e-287 783.0 COG1887@1|root,COG1887@2|Bacteria,1VD8C@1239|Firmicutes,4HI8C@91061|Bacilli,3F52X@33958|Lactobacillaceae 91061|Bacilli M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - - - - - - - - - - Glyphos_transf CAFIFDFH_00617 1423748.BALB01000004_gene503 1.42e-65 219.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase CAFIFDFH_00618 1423748.BALB01000004_gene503 5.34e-120 368.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase CAFIFDFH_00619 1423748.BALB01000004_gene503 3.35e-250 709.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase CAFIFDFH_00620 1423748.BALB01000004_gene503 2.13e-68 229.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase CAFIFDFH_00621 405566.lhv_1625 4.49e-168 469.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,3F4Z8@33958|Lactobacillaceae 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N CAFIFDFH_00622 1069534.LRC_10250 1.08e-52 178.0 COG1583@1|root,COG1583@2|Bacteria,1U7RP@1239|Firmicutes,4IHP0@91061|Bacilli,3FA2Q@33958|Lactobacillaceae 91061|Bacilli L CRISPR associated protein Cas6 - - - ko:K19091 - - - - ko00000,ko01000,ko02048 - - - Cas_Cas6 CAFIFDFH_00623 1069534.LRC_10240 1.67e-127 393.0 28HTI@1|root,2Z80D@2|Bacteria,1TPRZ@1239|Firmicutes,4HCA6@91061|Bacilli,3F9R1@33958|Lactobacillaceae 91061|Bacilli S CRISPR-associated protein (Cas_CXXC_CXXC) - - - ko:K19088 - - - - ko00000,ko02048 - - - Cas_CXXC_CXXC CAFIFDFH_00624 1069534.LRC_10230 1.12e-131 382.0 COG1857@1|root,COG1857@2|Bacteria,1TRGS@1239|Firmicutes,4HEVR@91061|Bacilli,3F9XP@33958|Lactobacillaceae 91061|Bacilli L CRISPR-associated negative auto-regulator DevR/Csa2 - - - ko:K19075 - - - - ko00000,ko02048 - - - DevR CAFIFDFH_00625 1423806.JCM15457_530 2.46e-83 256.0 COG1688@1|root,COG1688@2|Bacteria,1UYJD@1239|Firmicutes,4HGCF@91061|Bacilli,3F9RR@33958|Lactobacillaceae 91061|Bacilli L CRISPR-associated protein Cas5 - - - ko:K19090 - - - - ko00000,ko02048 - - - Cas_Cas5d CAFIFDFH_00626 1069534.LRC_10210 1.89e-217 639.0 COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,4HAH7@91061|Bacilli,3F4VV@33958|Lactobacillaceae 91061|Bacilli L CRISPR-associated helicase cas3 - - - ko:K07012 - - - - ko00000,ko01000,ko02048 - - - DEAD,HD,Helicase_C CAFIFDFH_00627 1069534.LRC_10200 1.46e-63 199.0 COG1468@1|root,COG1468@2|Bacteria,1V781@1239|Firmicutes,4IHG2@91061|Bacilli,3F9SX@33958|Lactobacillaceae 91061|Bacilli L Domain of unknown function DUF83 - - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - Cas_Cas4 CAFIFDFH_00628 1069534.LRC_10190 1.79e-155 445.0 COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,4HDKV@91061|Bacilli,3FBCR@33958|Lactobacillaceae 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1 CAFIFDFH_00629 1423806.JCM15457_525 9.43e-39 131.0 COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,4HKKP@91061|Bacilli 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas2 - - ko:K09951 - - - - ko00000,ko02048 - - - CRISPR_Cas2 CAFIFDFH_00630 405566.lhv_1617 0.0 1719.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,3F3ZA@33958|Lactobacillaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A CAFIFDFH_00631 326425.lhe_1494 6.45e-203 561.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,3F43E@33958|Lactobacillaceae 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS CAFIFDFH_00632 326425.lhe_1493 1.52e-136 387.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,3F6WF@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE CAFIFDFH_00633 326425.lhe_1492 3.16e-107 309.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,3F65S@33958|Lactobacillaceae 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone CAFIFDFH_00634 326425.lhe_1491 0.0 865.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4HE63@91061|Bacilli,3FB6I@33958|Lactobacillaceae 91061|Bacilli L Replication initiation and membrane attachment dnaB2 - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 CAFIFDFH_00635 326425.lhe_1490 1.08e-214 593.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,3F4JK@33958|Lactobacillaceae 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 CAFIFDFH_00636 326425.lhe_1489 0.0 1282.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,3F3TC@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD CAFIFDFH_00637 326425.lhe_1488 7.8e-119 340.0 29NRA@1|root,30A5W@2|Bacteria,1U68M@1239|Firmicutes,4IFZH@91061|Bacilli,3F7B3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00638 326425.lhe_1487 4.51e-124 353.0 29NRA@1|root,309P8@2|Bacteria,1U5FC@1239|Firmicutes,4IF6Y@91061|Bacilli,3F5US@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00640 326425.lhe_1523 0.0 904.0 29PCB@1|root,30AAJ@2|Bacteria,1V4H2@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - CAFIFDFH_00641 326425.lhe_1524 3.06e-157 440.0 COG0073@1|root,COG0073@2|Bacteria,1V7QA@1239|Firmicutes,4HJBD@91061|Bacilli,3FBJ0@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily XK27_10290 - - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind CAFIFDFH_00642 326425.lhe_1525 1.64e-72 217.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,3F72K@33958|Lactobacillaceae 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin CAFIFDFH_00643 405566.lhv_1653 7.82e-161 449.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,3F3QM@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 CAFIFDFH_00644 326425.lhe_1527 1.32e-271 744.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,3F4HH@33958|Lactobacillaceae 91061|Bacilli U ABC transporter ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB CAFIFDFH_00645 326425.lhe_1528 2.59e-174 486.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,3F444@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CAFIFDFH_00646 326425.lhe_1529 4.8e-72 216.0 COG3093@1|root,COG3093@2|Bacteria,1U65V@1239|Firmicutes,4IFVU@91061|Bacilli,3F752@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 CAFIFDFH_00647 405566.lhv_1658 1.33e-46 150.0 COG3549@1|root,COG3549@2|Bacteria,1U5QE@1239|Firmicutes,4IG85@91061|Bacilli,3F7U8@33958|Lactobacillaceae 91061|Bacilli S Plasmid maintenance system killer - - - - - - - - - - - - HigB-like_toxin CAFIFDFH_00648 1423748.BALB01000005_gene721 1.67e-104 301.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HJ19@91061|Bacilli,3FCD7@33958|Lactobacillaceae 91061|Bacilli FG Scavenger mRNA decapping enzyme C-term binding hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT CAFIFDFH_00649 326425.lhe_1532 6.03e-57 178.0 29P5R@1|root,30A3W@2|Bacteria,1U65N@1239|Firmicutes,4IFVH@91061|Bacilli,3F74E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - YtxH CAFIFDFH_00650 326425.lhe_1533 8.01e-200 555.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,3FB3Y@33958|Lactobacillaceae 91061|Bacilli M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 CAFIFDFH_00651 326425.lhe_1534 6.37e-102 294.0 COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli,3F45M@33958|Lactobacillaceae 91061|Bacilli S PAS domain XK27_04775 - - ko:K09155 - - - - ko00000 - - - DUF438,Hemerythrin,PAS_10 CAFIFDFH_00652 326425.lhe_1535 2.85e-242 664.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,3F4SF@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon CAFIFDFH_00653 326425.lhe_1536 0.0 1412.0 COG0419@1|root,COG4717@1|root,COG0419@2|Bacteria,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,3F3PF@33958|Lactobacillaceae 91061|Bacilli L AAA domain yhaN - - - - - - - - - - - AAA_27 CAFIFDFH_00654 326425.lhe_1537 6.08e-294 802.0 COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,3F3PX@33958|Lactobacillaceae 91061|Bacilli L Ser Thr phosphatase family protein yhaO - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,Metallophos_2 CAFIFDFH_00655 405566.lhv_1666 2.07e-73 220.0 COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HKKC@91061|Bacilli,3F822@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0342 family yheA - - - - - - - - - - - Com_YlbF CAFIFDFH_00656 326425.lhe_1539 0.0 1360.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F49Q@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein pbp2A - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase CAFIFDFH_00657 405566.lhv_1668 2.09e-208 575.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,3F50K@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 CAFIFDFH_00658 326425.lhe_1540 3.51e-30 106.0 COG2723@1|root,COG2723@2|Bacteria 2|Bacteria G beta-glucosidase activity bglH - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 CAFIFDFH_00659 1423748.BALB01000005_gene707 3.87e-12 65.5 COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,4HJM8@91061|Bacilli,3F577@33958|Lactobacillaceae 91061|Bacilli C FMN-dependent dehydrogenase - - - - - - - - - - - - FMN_dh CAFIFDFH_00660 326425.lhe_1542 2.48e-175 489.0 COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,4HC2G@91061|Bacilli,3FB84@33958|Lactobacillaceae 91061|Bacilli S MgtC family mgtC3 - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC CAFIFDFH_00661 326425.lhe_1543 3.69e-180 501.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,3F4J6@33958|Lactobacillaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP CAFIFDFH_00662 326425.lhe_1544 7.15e-73 218.0 2AE03@1|root,313SN@2|Bacteria,1U624@1239|Firmicutes,4IFR4@91061|Bacilli,3F6UV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00663 326425.lhe_1545 1.29e-191 532.0 COG1767@1|root,COG1767@2|Bacteria,1TQGQ@1239|Firmicutes,4HGCS@91061|Bacilli,3F4SU@33958|Lactobacillaceae 91061|Bacilli H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase citG - 2.4.2.52 ko:K05966 ko02020,map02020 - R09675 RC00049,RC00063 ko00000,ko00001,ko01000 - - - CitG,CitX CAFIFDFH_00665 326425.lhe_1549 1.3e-199 553.0 COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,4HC4E@91061|Bacilli,3FBEP@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family yitS - - - - - - - - - - - DegV CAFIFDFH_00666 326425.lhe_1550 3.65e-109 314.0 COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes,4HPH8@91061|Bacilli,3F6W4@33958|Lactobacillaceae 91061|Bacilli K Domain of unknown function (DUF1836) - - - - - - - - - - - - DUF1836 CAFIFDFH_00667 405566.lhv_1602 3.05e-244 677.0 COG1808@1|root,COG1808@2|Bacteria,1TRFZ@1239|Firmicutes,4HEZ0@91061|Bacilli,3F4KN@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF389) - - - - - - - - - - - - DUF389 CAFIFDFH_00668 1423748.BALB01000003_gene394 1.3e-296 815.0 28MBK@1|root,2ZAQ1@2|Bacteria,1TSWC@1239|Firmicutes,4HCSW@91061|Bacilli,3F50E@33958|Lactobacillaceae 91061|Bacilli M Arylsulfotransferase Ig-like domain astA - 2.8.2.22 ko:K01023 - - - - ko00000,ko01000 - - - Arylsulfotran_N,Arylsulfotrans CAFIFDFH_00669 326425.lhe_1481 1.44e-74 223.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,3F4MS@33958|Lactobacillaceae 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N CAFIFDFH_00670 326425.lhe_1480 9.64e-38 126.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,3F7CQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p CAFIFDFH_00671 1423767.BALU01000009_gene397 1.23e-75 226.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,3F6HZ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 CAFIFDFH_00672 405566.lhv_1595 1.51e-121 347.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,3F46V@33958|Lactobacillaceae 91061|Bacilli S HAD phosphatase, family IIIA yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase CAFIFDFH_00673 405566.lhv_1594 4.97e-272 743.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,3F4JU@33958|Lactobacillaceae 91061|Bacilli S Ribosome biogenesis GTPase YqeH yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 CAFIFDFH_00674 326425.lhe_1476 3.17e-156 438.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,3F4D6@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like CAFIFDFH_00675 326425.lhe_1475 1.59e-141 399.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,3F47C@33958|Lactobacillaceae 91061|Bacilli H Hydrolase, HD family yqeK - - - - - - - - - - - HD CAFIFDFH_00676 326425.lhe_1474 2.08e-77 230.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,3F7QN@33958|Lactobacillaceae 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS CAFIFDFH_00677 405566.lhv_1590 3.81e-274 750.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,3F3QC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 CAFIFDFH_00678 405566.lhv_1589 2.03e-124 355.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,3F61Z@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized ACR, COG1399 ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 CAFIFDFH_00679 326425.lhe_1471 2.12e-164 460.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,3F421@33958|Lactobacillaceae 91061|Bacilli K response regulator csrR - - - - - - - - - - - Response_reg,Trans_reg_C CAFIFDFH_00680 326425.lhe_1470 0.0 967.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,3F3NU@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA CAFIFDFH_00681 326425.lhe_1469 1.67e-110 318.0 COG3760@1|root,COG3760@2|Bacteria,1V29H@1239|Firmicutes,4HP8F@91061|Bacilli,3F6ZD@33958|Lactobacillaceae 91061|Bacilli S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit CAFIFDFH_00682 405566.lhv_1585 3e-205 570.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli,3F3P3@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP CAFIFDFH_00683 326425.lhe_1467 3.23e-58 180.0 COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,4HNN7@91061|Bacilli,3F81R@33958|Lactobacillaceae 91061|Bacilli C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020 Acylphosphatase CAFIFDFH_00684 326425.lhe_1466 1.05e-177 495.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,3F3NF@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind CAFIFDFH_00685 326425.lhe_1465 1.26e-43 143.0 COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,3F7FK@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, HxlR family yodB GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HxlR CAFIFDFH_00686 405566.lhv_1581 1.1e-258 708.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,3F4NT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d CAFIFDFH_00687 326425.lhe_1463 0.0 1599.0 COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,3F3V3@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind CAFIFDFH_00688 326425.lhe_1462 2.74e-89 264.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,3F4ZF@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N CAFIFDFH_00689 326425.lhe_1461 1.79e-214 592.0 COG0039@1|root,COG0039@2|Bacteria,1TQIV@1239|Firmicutes,4IQTH@91061|Bacilli,3FBIV@33958|Lactobacillaceae 91061|Bacilli C lactate/malate dehydrogenase, alpha/beta C-terminal domain ldh3 - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N CAFIFDFH_00690 326425.lhe_1460 2.97e-76 227.0 COG4679@1|root,COG4679@2|Bacteria,1VB8K@1239|Firmicutes,4HKT7@91061|Bacilli,3F7HF@33958|Lactobacillaceae 91061|Bacilli S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 CAFIFDFH_00691 326425.lhe_1459 5.83e-52 164.0 COG3620@1|root,COG3620@2|Bacteria,1UJGN@1239|Firmicutes,4IT9F@91061|Bacilli,3FBV2@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 CAFIFDFH_00692 1033837.WANG_0855 8.55e-47 153.0 2BT6P@1|root,32NBV@2|Bacteria,1TU7K@1239|Firmicutes,4II8D@91061|Bacilli,3FARS@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K19167 - - - - ko00000,ko02048 - - - - CAFIFDFH_00693 1033837.WANG_p1103 9.33e-310 845.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F55P@33958|Lactobacillaceae 91061|Bacilli L transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon CAFIFDFH_00694 326425.lhe_0809 5.59e-220 607.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,3FBT4@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 yfdH - - ko:K12999,ko:K20534 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 CAFIFDFH_00695 1033837.WANG_0858 1.2e-87 258.0 COG2246@1|root,COG2246@2|Bacteria,1VP71@1239|Firmicutes,4HSE0@91061|Bacilli,3F73E@33958|Lactobacillaceae 91061|Bacilli S GtrA-like protein - - - - - - - - - - - - GtrA CAFIFDFH_00696 1033837.WANG_0859 7.94e-176 494.0 COG0584@1|root,COG0584@2|Bacteria,1V3Z1@1239|Firmicutes,4IEZK@91061|Bacilli,3F555@33958|Lactobacillaceae 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family - - - - - - - - - - - - GDPD CAFIFDFH_00697 1033837.WANG_0859 1.28e-68 216.0 COG0584@1|root,COG0584@2|Bacteria,1V3Z1@1239|Firmicutes,4IEZK@91061|Bacilli,3F555@33958|Lactobacillaceae 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family - - - - - - - - - - - - GDPD CAFIFDFH_00698 1033837.WANG_0860 3.07e-32 112.0 2BN97@1|root,32GWQ@2|Bacteria,1U7X0@1239|Firmicutes,4IHUC@91061|Bacilli,3FA9Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00699 1033837.WANG_1282 4.34e-217 603.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,3F4RA@33958|Lactobacillaceae 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut CAFIFDFH_00700 1033837.WANG_1269 4.68e-24 99.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,3F4RA@33958|Lactobacillaceae 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut CAFIFDFH_00701 1423748.BALB01000001_gene75 5.9e-71 216.0 29NJE@1|root,30B6P@2|Bacteria,1U7MU@1239|Firmicutes,4IHJ3@91061|Bacilli,3F9XA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00702 326425.lhe_0802 3.15e-53 175.0 29NJE@1|root,309HA@2|Bacteria,1U53D@1239|Firmicutes,4IEUP@91061|Bacilli,3F4BT@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19 CAFIFDFH_00703 405566.lhv_0833 4.46e-165 462.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,3F41G@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 CAFIFDFH_00704 1033837.WANG_0330 1.97e-20 88.6 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,3F4RA@33958|Lactobacillaceae 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut CAFIFDFH_00705 1423790.BN53_00815 7.8e-49 165.0 COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,4HEX8@91061|Bacilli,3F5HS@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_5,DDE_Tnp_1 CAFIFDFH_00706 525365.HMPREF0548_1647 5.52e-36 127.0 COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,4HEX8@91061|Bacilli,3F5HS@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_5,DDE_Tnp_1 CAFIFDFH_00707 405566.lhv_0829 1.9e-190 528.0 29NJE@1|root,309TC@2|Bacteria,1U5NC@1239|Firmicutes,4IFD2@91061|Bacilli,3F67W@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_3 CAFIFDFH_00709 405566.lhv_0826 4.35e-173 485.0 29NJE@1|root,30ACF@2|Bacteria,1U6GH@1239|Firmicutes,4IG8N@91061|Bacilli,3F7VG@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 CAFIFDFH_00710 405566.lhv_0825 2.5e-192 533.0 29NJE@1|root,309HA@2|Bacteria,1U53D@1239|Firmicutes,4IEUP@91061|Bacilli,3F4BT@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19 CAFIFDFH_00711 405566.lhv_0824 4.31e-123 351.0 29PIE@1|root,30AGJ@2|Bacteria,1U6MT@1239|Firmicutes,4IGEK@91061|Bacilli,3F85X@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3232) - - - - - - - - - - - - DUF3232 CAFIFDFH_00712 525365.HMPREF0548_0178 1.19e-17 80.5 29NJE@1|root,30A94@2|Bacteria,1U6CJ@1239|Firmicutes,4IG48@91061|Bacilli,3F7KV@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 CAFIFDFH_00713 405566.lhv_0823 1.13e-293 801.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,3F3N0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI CAFIFDFH_00714 405566.lhv_0822 5.46e-280 765.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,3F4CD@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 CAFIFDFH_00715 326425.lhe_0793 0.0 1012.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,3F47K@33958|Lactobacillaceae 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA CAFIFDFH_00716 326425.lhe_0792 1.52e-142 402.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,3F3P0@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 CAFIFDFH_00717 326425.lhe_0791 1.83e-106 307.0 COG5506@1|root,COG5506@2|Bacteria,1V8ID@1239|Firmicutes,4HJTQ@91061|Bacilli,3FCEV@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1694) - - - - - - - - - - - - DUF1694 CAFIFDFH_00718 326425.lhe_0790 6.82e-309 842.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3WF@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N CAFIFDFH_00719 405566.lhv_2404 4.53e-55 172.0 29P9A@1|root,30A7E@2|Bacteria,1U6AF@1239|Firmicutes,4IG1T@91061|Bacilli,3F7FU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00720 326425.lhe_0789 1.34e-103 300.0 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,3F68T@33958|Lactobacillaceae 91061|Bacilli T universal stress protein uspA - - - - - - - - - - - Usp CAFIFDFH_00721 748671.LCRIS_01512 2.88e-18 84.7 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,3F4UD@33958|Lactobacillaceae 91061|Bacilli G invertase sacA - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 iYO844.BSU38040 Glyco_hydro_32C,Glyco_hydro_32N CAFIFDFH_00722 748671.LCRIS_01510 9.74e-84 265.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system scrA5 - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC CAFIFDFH_00723 748671.LCRIS_01510 1.62e-18 86.7 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system scrA5 - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC CAFIFDFH_00724 748671.LCRIS_01509 1.47e-76 249.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,3F3RU@33958|Lactobacillaceae 91061|Bacilli G alpha-galactosidase melA - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase CAFIFDFH_00725 405566.lhv_0480 3.73e-239 657.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4HTTA@91061|Bacilli,3FC7R@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component manL - 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man,PTSIIB_sorb CAFIFDFH_00726 326425.lhe_0492 1.04e-180 504.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli,3F3V5@33958|Lactobacillaceae 91061|Bacilli G PTS system manY - - ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277 R02630,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.4 - - EII-Sor CAFIFDFH_00727 326425.lhe_0493 3.51e-222 612.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component manN - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA CAFIFDFH_00728 326425.lhe_0494 2.76e-83 246.0 COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes,4HX8Z@91061|Bacilli,3FB56@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF956) - - - - - - - - - - - - DUF956 CAFIFDFH_00729 326425.lhe_0495 4.31e-192 533.0 COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HAZB@91061|Bacilli,3F3VP@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate CAFIFDFH_00730 405566.lhv_0486 2.32e-110 318.0 COG0110@1|root,COG0110@2|Bacteria,1TSQQ@1239|Firmicutes,4HJJ7@91061|Bacilli,3F73Z@33958|Lactobacillaceae 91061|Bacilli S transferase hexapeptide repeat - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2 CAFIFDFH_00731 326425.lhe_0497 1.32e-307 841.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease cycA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease CAFIFDFH_00732 326425.lhe_0498 0.0 1726.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli,3F3RN@33958|Lactobacillaceae 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH CAFIFDFH_00733 326425.lhe_0499 0.0 1179.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,3F467@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS CAFIFDFH_00734 326425.lhe_0500 7.04e-63 192.0 29Q9E@1|root,30B8I@2|Bacteria,1U7QQ@1239|Firmicutes,4IHN0@91061|Bacilli,3FA10@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00735 405566.lhv_0493 3.03e-60 189.0 COG0531@1|root,COG0531@2|Bacteria,1UZNT@1239|Firmicutes,4HFMI@91061|Bacilli,3F3SX@33958|Lactobacillaceae 91061|Bacilli E amino acid - - - - - - - - - - - - AA_permease_2 CAFIFDFH_00736 405566.lhv_0493 1.55e-58 185.0 COG0531@1|root,COG0531@2|Bacteria,1UZNT@1239|Firmicutes,4HFMI@91061|Bacilli,3F3SX@33958|Lactobacillaceae 91061|Bacilli E amino acid - - - - - - - - - - - - AA_permease_2 CAFIFDFH_00737 405566.lhv_0494 1.83e-93 273.0 2DIUI@1|root,3045J@2|Bacteria,1U78P@1239|Firmicutes,4IH3J@91061|Bacilli,3F94E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Gram_pos_anchor CAFIFDFH_00738 405566.lhv_0496 2.61e-124 363.0 2BJNP@1|root,32E07@2|Bacteria,1U7M2@1239|Firmicutes,4IHI5@91061|Bacilli,3F9W4@33958|Lactobacillaceae 91061|Bacilli S LPXTG cell wall anchor motif - - - - - - - - - - - - Gram_pos_anchor CAFIFDFH_00739 405566.lhv_0497 6.84e-277 758.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase CAFIFDFH_00740 326425.lhe_0504 2.05e-42 144.0 COG0599@1|root,COG0599@2|Bacteria,1TQGP@1239|Firmicutes,4HH3D@91061|Bacilli,3FBCM@33958|Lactobacillaceae 91061|Bacilli S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD CAFIFDFH_00741 326425.lhe_0504 3.02e-81 245.0 COG0599@1|root,COG0599@2|Bacteria,1TQGP@1239|Firmicutes,4HH3D@91061|Bacilli,3FBCM@33958|Lactobacillaceae 91061|Bacilli S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD CAFIFDFH_00742 1423748.BALB01000025_gene1778 2.25e-49 156.0 29PH8@1|root,30A80@2|Bacteria,1U6B8@1239|Firmicutes,4IG2S@91061|Bacilli,3F7HY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00743 1423748.BALB01000025_gene1779 2.27e-81 242.0 COG1051@1|root,COG1051@2|Bacteria,1VAMK@1239|Firmicutes,4HKCB@91061|Bacilli,3F6NU@33958|Lactobacillaceae 91061|Bacilli F Nudix hydrolase apfA - 3.6.1.61 ko:K18445 ko00230,map00230 - R00184 RC00002 ko00000,ko00001,ko01000 - - - NUDIX CAFIFDFH_00744 1033837.WANG_1191 2.19e-15 74.7 COG1866@1|root,COG1866@2|Bacteria,1TPXB@1239|Firmicutes,4IS6N@91061|Bacilli,3F4N4@33958|Lactobacillaceae 91061|Bacilli H Phosphoenolpyruvate carboxykinase pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP CAFIFDFH_00745 1033837.WANG_1191 5.29e-17 80.5 COG1866@1|root,COG1866@2|Bacteria,1TPXB@1239|Firmicutes,4IS6N@91061|Bacilli,3F4N4@33958|Lactobacillaceae 91061|Bacilli H Phosphoenolpyruvate carboxykinase pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP CAFIFDFH_00746 1033837.WANG_1191 6.68e-33 125.0 COG1866@1|root,COG1866@2|Bacteria,1TPXB@1239|Firmicutes,4IS6N@91061|Bacilli,3F4N4@33958|Lactobacillaceae 91061|Bacilli H Phosphoenolpyruvate carboxykinase pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP CAFIFDFH_00747 1423748.BALB01000025_gene1782 4.53e-64 209.0 COG1866@1|root,COG1866@2|Bacteria,1TPXB@1239|Firmicutes,4IS6N@91061|Bacilli,3F4N4@33958|Lactobacillaceae 91061|Bacilli H Phosphoenolpyruvate carboxykinase pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP CAFIFDFH_00748 1423748.BALB01000025_gene1782 2.35e-70 226.0 COG1866@1|root,COG1866@2|Bacteria,1TPXB@1239|Firmicutes,4IS6N@91061|Bacilli,3F4N4@33958|Lactobacillaceae 91061|Bacilli H Phosphoenolpyruvate carboxykinase pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP CAFIFDFH_00749 1423748.BALB01000025_gene1782 5.01e-36 134.0 COG1866@1|root,COG1866@2|Bacteria,1TPXB@1239|Firmicutes,4IS6N@91061|Bacilli,3F4N4@33958|Lactobacillaceae 91061|Bacilli H Phosphoenolpyruvate carboxykinase pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP CAFIFDFH_00750 1423748.BALB01000004_gene529 1.94e-71 222.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4H9XJ@91061|Bacilli,3FB4Q@33958|Lactobacillaceae 91061|Bacilli S reductase - - 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red CAFIFDFH_00751 1423748.BALB01000004_gene529 7.14e-61 194.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4H9XJ@91061|Bacilli,3FB4Q@33958|Lactobacillaceae 91061|Bacilli S reductase - - 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red CAFIFDFH_00752 326425.lhe_0623 1.6e-305 834.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,3F3UJ@33958|Lactobacillaceae 91061|Bacilli F Permease pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease CAFIFDFH_00753 326425.lhe_0622 1.62e-117 337.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,3F4MT@33958|Lactobacillaceae 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran CAFIFDFH_00754 326425.lhe_0621 0.0 904.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator qacA - - - - - - - - - - - MFS_1 CAFIFDFH_00755 405566.lhv_0584 1.07e-96 291.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9UE@91061|Bacilli,3FCA7@33958|Lactobacillaceae 91061|Bacilli EGP MFS_1 like family pmrA - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr CAFIFDFH_00756 326425.lhe_0620 2.15e-152 436.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9UE@91061|Bacilli,3FCA7@33958|Lactobacillaceae 91061|Bacilli EGP MFS_1 like family pmrA - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr CAFIFDFH_00757 326425.lhe_0619 1.25e-265 726.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,3F55I@33958|Lactobacillaceae 91061|Bacilli E M42 glutamyl aminopeptidase pepA - - - - - - - - - - - Peptidase_M42 CAFIFDFH_00758 326425.lhe_0618 0.0 1065.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,3F3ZJ@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn CAFIFDFH_00759 405566.lhv_0587 1.18e-14 71.2 29NJ9@1|root,309H6@2|Bacteria,1U538@1239|Firmicutes,4IEUK@91061|Bacilli,3F4AG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00760 405566.lhv_0587 4.35e-159 447.0 29NJ9@1|root,309H6@2|Bacteria,1U538@1239|Firmicutes,4IEUK@91061|Bacilli,3F4AG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00761 326425.lhe_0616 6.17e-165 460.0 COG0518@1|root,COG0518@2|Bacteria,1UAH0@1239|Firmicutes,4HHTX@91061|Bacilli,3F4AV@33958|Lactobacillaceae 91061|Bacilli F glutamine amidotransferase - - - - - - - - - - - - GATase CAFIFDFH_00762 326425.lhe_0615 1.06e-190 530.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HBM1@91061|Bacilli,3FC55@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter peb1A - - ko:K10039 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 CAFIFDFH_00763 326425.lhe_0614 7.56e-106 305.0 COG1846@1|root,COG1846@2|Bacteria,1VF1A@1239|Firmicutes,4HH6N@91061|Bacilli,3F705@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, MarR family - - - - - - - - - - - - HTH_27,MarR_2 CAFIFDFH_00764 326425.lhe_0613 0.0 1048.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein XK27_09600 - - ko:K06147,ko:K18891 ko02010,map02010 M00708 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 - - ABC_membrane,ABC_tran CAFIFDFH_00765 326425.lhe_0612 0.0 1113.0 COG1132@1|root,COG1132@2|Bacteria,1UNRI@1239|Firmicutes,4HFD4@91061|Bacilli,3FC4R@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region XK27_09605 - - ko:K18892 ko02010,map02010 M00708 - - ko00000,ko00001,ko00002,ko02000 3.A.1.135 - - ABC_membrane,ABC_tran CAFIFDFH_00766 326425.lhe_0611 6.25e-132 374.0 COG4721@1|root,COG4721@2|Bacteria,1V39N@1239|Firmicutes,4HF32@91061|Bacilli,3F4QM@33958|Lactobacillaceae 91061|Bacilli S ABC-type cobalt transport system, permease component ykoE - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt CAFIFDFH_00767 326425.lhe_0610 5.64e-173 483.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - - ko:K10041 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran CAFIFDFH_00768 326425.lhe_0609 5.69e-195 540.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli,3F4GG@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein glnH - - ko:K10039 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 CAFIFDFH_00769 326425.lhe_0608 3.66e-139 394.0 COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HFBH@91061|Bacilli,3F3XW@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnM GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 CAFIFDFH_00770 326425.lhe_0607 1.27e-141 401.0 COG0765@1|root,COG0765@2|Bacteria,1UJM4@1239|Firmicutes,4HBAS@91061|Bacilli,3F3WJ@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 CAFIFDFH_00771 405566.lhv_0602 2.52e-81 241.0 2CJHH@1|root,32SA1@2|Bacteria,1V6G9@1239|Firmicutes,4HIZ6@91061|Bacilli,3F5FF@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 CAFIFDFH_00772 1423748.BALB01000002_gene238 1.47e-06 48.9 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HF5U@91061|Bacilli,3FCCC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC CAFIFDFH_00773 326425.lhe_1694 7.41e-255 700.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,3F4AX@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 CAFIFDFH_00774 326425.lhe_1695 3.93e-134 380.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,3F522@33958|Lactobacillaceae 91061|Bacilli K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 CAFIFDFH_00775 405566.lhv_0411 5.64e-172 480.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,3F3WV@33958|Lactobacillaceae 91061|Bacilli O Universal bacterial protein YeaZ yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 CAFIFDFH_00776 405566.lhv_0410 1.06e-111 322.0 2DNHW@1|root,32XKY@2|Bacteria,1VGAX@1239|Firmicutes,4ISA7@91061|Bacilli,3FBRP@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt CAFIFDFH_00777 326425.lhe_1698 1.91e-179 499.0 COG3884@1|root,COG3884@2|Bacteria,1V3RB@1239|Firmicutes,4HHJ4@91061|Bacilli,3F41B@33958|Lactobacillaceae 91061|Bacilli I Acyl-ACP thioesterase fat - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE CAFIFDFH_00778 326425.lhe_1699 8.11e-201 556.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,3F4AI@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase CAFIFDFH_00779 326425.lhe_1700 1.99e-80 238.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli,3F864@33958|Lactobacillaceae 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB CAFIFDFH_00780 326425.lhe_1701 6.9e-198 549.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,3F50D@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C CAFIFDFH_00781 405566.lhv_0405 1.52e-68 207.0 COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,3F6VW@33958|Lactobacillaceae 91061|Bacilli S Cyclic-di-AMP receptor yaaQ - - - - - - - - - - - CdAMP_rec CAFIFDFH_00782 326425.lhe_1703 8.42e-149 419.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,3F4JR@33958|Lactobacillaceae 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin CAFIFDFH_00783 326425.lhe_1704 3.33e-47 151.0 29PC5@1|root,30AAD@2|Bacteria,1U6E6@1239|Firmicutes,4IG5Y@91061|Bacilli,3F7PR@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2508) - - - - - - - - - - - - DUF2508 CAFIFDFH_00784 326425.lhe_1705 6.48e-142 400.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,3F4JQ@33958|Lactobacillaceae 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 CAFIFDFH_00785 1423748.BALB01000002_gene252 6.03e-57 178.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,3F7F3@33958|Lactobacillaceae 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd CAFIFDFH_00786 405566.lhv_0400 0.0 1125.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,3F3P2@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 CAFIFDFH_00787 326425.lhe_1708 9.21e-120 342.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,3F6IS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam CAFIFDFH_00788 326425.lhe_1709 9.5e-149 418.0 COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HHCA@91061|Bacilli,3F4NU@33958|Lactobacillaceae 91061|Bacilli J Methyltransferase rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS CAFIFDFH_00789 1423748.BALB01000002_gene255 4.28e-111 333.0 COG1340@1|root,COG2813@1|root,COG1340@2|Bacteria,COG2813@2|Bacteria,1UI94@1239|Firmicutes,4HFS7@91061|Bacilli,3FBT5@33958|Lactobacillaceae 91061|Bacilli J Ion channel - - 2.1.1.172 ko:K00564,ko:K10716 - - R07234 RC00003 ko00000,ko01000,ko02000,ko03009 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2 CAFIFDFH_00790 1423748.BALB01000002_gene256 1.61e-72 218.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,3F6YA@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N CAFIFDFH_00791 326425.lhe_1712 3.72e-111 320.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,3F4S4@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 CAFIFDFH_00792 1423748.BALB01000002_gene258 1.04e-201 561.0 COG0679@1|root,COG0679@2|Bacteria,1VDS9@1239|Firmicutes,4HQT5@91061|Bacilli,3F5JF@33958|Lactobacillaceae 91061|Bacilli S Membrane transport protein ywkB - - ko:K07088 - - - - ko00000 - - - Mem_trans CAFIFDFH_00793 272621.LBA0367 1.88e-34 127.0 COG0679@1|root,COG0679@2|Bacteria,1VDS9@1239|Firmicutes,4HQT5@91061|Bacilli,3F5JF@33958|Lactobacillaceae 91061|Bacilli S Membrane transport protein ywkB - - ko:K07088 - - - - ko00000 - - - Mem_trans CAFIFDFH_00794 326425.lhe_1714 6.81e-150 422.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,3F46W@33958|Lactobacillaceae 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU CAFIFDFH_00795 326425.lhe_1715 2.31e-179 499.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB1 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran CAFIFDFH_00796 326425.lhe_1716 1.5e-186 518.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB2 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran CAFIFDFH_00797 326425.lhe_1717 9.02e-199 552.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,3F412@33958|Lactobacillaceae 91061|Bacilli P Phosphate transport system permease protein PstA pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 CAFIFDFH_00798 326425.lhe_1718 1.41e-220 610.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,3F3NI@33958|Lactobacillaceae 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 CAFIFDFH_00799 405566.lhv_0387 2.71e-201 558.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 CAFIFDFH_00800 272621.LBA1377 1.21e-50 185.0 29WY6@1|root,30IKC@2|Bacteria,1V8N3@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - CW_binding_1,NPCBM CAFIFDFH_00802 326425.lhe_1358 1.82e-194 540.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,3F4K2@33958|Lactobacillaceae 91061|Bacilli U sugar transport - - - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport CAFIFDFH_00803 326425.lhe_1357 1.9e-65 198.0 2DKNK@1|root,30A2I@2|Bacteria,1U63R@1239|Firmicutes,4IFT6@91061|Bacilli,3F6YT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00804 326425.lhe_1356 5.88e-103 297.0 COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,4HGWN@91061|Bacilli,3F6H4@33958|Lactobacillaceae 91061|Bacilli O peptide methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR CAFIFDFH_00805 405566.lhv_1436 0.0 1612.0 COG2936@1|root,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4IRQ0@91061|Bacilli,3FCF2@33958|Lactobacillaceae 91061|Bacilli E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline pepX - 3.4.14.11 ko:K01281 - - - - ko00000,ko01000,ko01002 - - - PepX_C,PepX_N,Peptidase_S15 CAFIFDFH_00806 748671.LCRIS_01361 4.97e-30 108.0 2DKR3@1|root,30AEW@2|Bacteria,1U6JT@1239|Firmicutes,4IGCA@91061|Bacilli,3F81U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00807 405566.lhv_1435 6.33e-87 254.0 COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli,3F72U@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ArsC family yusI - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin CAFIFDFH_00808 326425.lhe_1352 2.59e-229 629.0 COG0657@1|root,COG0657@2|Bacteria,1V2AW@1239|Firmicutes,4HU2V@91061|Bacilli,3F3N7@33958|Lactobacillaceae 91061|Bacilli I Carboxylesterase family lipA - - - - - - - - - - - Abhydrolase_3 CAFIFDFH_00810 405566.lhv_1433 2.05e-275 755.0 COG3757@1|root,COG3757@2|Bacteria,1VF8D@1239|Firmicutes,4HX0U@91061|Bacilli,3F4U9@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,LysM,SH3_5,SLAP CAFIFDFH_00811 405566.lhv_1432 0.0 1090.0 COG4907@1|root,COG4907@2|Bacteria,1TS3Q@1239|Firmicutes,4HF7D@91061|Bacilli,3F4AT@33958|Lactobacillaceae 91061|Bacilli S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 CAFIFDFH_00812 1033837.WANG_0371 3.45e-37 124.0 COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli,3F83T@33958|Lactobacillaceae 91061|Bacilli G Belongs to the 4-oxalocrotonate tautomerase family dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase CAFIFDFH_00813 326425.lhe_1347 1.35e-165 462.0 2E7EK@1|root,331XM@2|Bacteria,1VBTT@1239|Firmicutes,4HMT5@91061|Bacilli,3F4W0@33958|Lactobacillaceae 91061|Bacilli S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) - - - - - - - - - - - - G6PD_bact CAFIFDFH_00814 326425.lhe_1346 1.97e-257 704.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli,3F4BD@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 CAFIFDFH_00815 326425.lhe_1345 0.0 880.0 2EM25@1|root,33ERN@2|Bacteria,1VK4A@1239|Firmicutes,4HRGD@91061|Bacilli,3F53P@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2325) - - - - - - - - - - - - DUF2325 CAFIFDFH_00816 1423748.BALB01000011_gene1170 6.82e-66 200.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,3F6WT@33958|Lactobacillaceae 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p CAFIFDFH_00817 326425.lhe_1343 1.6e-63 194.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,3F6WU@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 CAFIFDFH_00818 326425.lhe_1342 6.85e-143 409.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,3F4DR@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 CAFIFDFH_00819 326425.lhe_1341 1.04e-133 379.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F422@33958|Lactobacillaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C CAFIFDFH_00820 326425.lhe_1340 6.6e-91 266.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,3F71X@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function WQ51_04310 - - ko:K10947 - - - - ko00000,ko03000 - - - Asp23 CAFIFDFH_00821 326425.lhe_1339 1.28e-85 252.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,3F7KW@33958|Lactobacillaceae 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB CAFIFDFH_00822 326425.lhe_1337 1e-155 439.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,3F46A@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C CAFIFDFH_00823 326425.lhe_1336 2.23e-226 633.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,3F4RE@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 CAFIFDFH_00824 326425.lhe_1335 7.59e-48 153.0 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,3F81K@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S CAFIFDFH_00825 326425.lhe_1334 6.71e-207 572.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,3F436@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt CAFIFDFH_00826 326425.lhe_1333 8.78e-198 547.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,3F45T@33958|Lactobacillaceae 91061|Bacilli J Ribosomal RNA large subunit methyltransferase J rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 CAFIFDFH_00827 326425.lhe_1332 0.0 1056.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,3F43U@33958|Lactobacillaceae 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N CAFIFDFH_00828 405566.lhv_1409 3.93e-28 104.0 COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli,3F7EV@33958|Lactobacillaceae 91061|Bacilli S ASCH - - - - - - - - - - - - ASCH CAFIFDFH_00829 405566.lhv_1409 6.84e-57 178.0 COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli,3F7EV@33958|Lactobacillaceae 91061|Bacilli S ASCH - - - - - - - - - - - - ASCH CAFIFDFH_00830 326425.lhe_1330 7.26e-146 410.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,3F3X9@33958|Lactobacillaceae 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin CAFIFDFH_00831 1423748.BALB01000011_gene1155 5.6e-45 145.0 COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4HNHS@91061|Bacilli,3F81N@33958|Lactobacillaceae 91061|Bacilli K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 CAFIFDFH_00832 405566.lhv_1406 0.0 1571.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,3F3N8@33958|Lactobacillaceae 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII CAFIFDFH_00833 326425.lhe_1327 1.87e-221 611.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,3F4N7@33958|Lactobacillaceae 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N CAFIFDFH_00834 405566.lhv_1404 4.49e-315 859.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,3F45F@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB CAFIFDFH_00835 326425.lhe_1325 8.11e-190 527.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,3F4UI@33958|Lactobacillaceae 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 CAFIFDFH_00836 326425.lhe_1324 0.0 1224.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase CAFIFDFH_00837 405566.lhv_1401 5.56e-214 590.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,3F3XH@33958|Lactobacillaceae 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N CAFIFDFH_00838 326425.lhe_1322 2.51e-152 428.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,3F4KX@33958|Lactobacillaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim CAFIFDFH_00839 405566.lhv_1399 8.07e-164 458.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,3F4N8@33958|Lactobacillaceae 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic CAFIFDFH_00840 326425.lhe_1320 1.06e-68 207.0 2AE84@1|root,31424@2|Bacteria,1U65W@1239|Firmicutes,4IFVX@91061|Bacilli,3F756@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00841 326425.lhe_1319 1.33e-35 120.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli,3F7ZN@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 CAFIFDFH_00842 1423748.BALB01000011_gene1141 1.67e-74 223.0 COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,3F72W@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function yloU - - - - - - - - - - - Asp23 CAFIFDFH_00843 326425.lhe_1317 0.0 1061.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,3F3X0@33958|Lactobacillaceae 91061|Bacilli S DAK2 domain fusion protein YloV yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 CAFIFDFH_00844 326425.lhe_1316 0.0 1313.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,3F3JW@33958|Lactobacillaceae 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge CAFIFDFH_00845 405566.lhv_1393 3.69e-233 642.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,3F4N9@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis CAFIFDFH_00846 326425.lhe_1314 5.34e-48 153.0 COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,3F7F4@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CAFIFDFH_00847 405566.lhv_1391 6.3e-251 688.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3F41T@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY CAFIFDFH_00848 326425.lhe_1312 3.56e-233 642.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,3F4GM@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY CAFIFDFH_00849 1033837.WANG_0407 7.39e-226 622.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,3FCCU@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease oppB - - ko:K02033,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 CAFIFDFH_00850 326425.lhe_1310 2.89e-202 562.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HDIR@91061|Bacilli,3FCB7@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component oppC5 - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N CAFIFDFH_00851 326425.lhe_1309 0.0 1161.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 CAFIFDFH_00852 326425.lhe_1308 0.0 1037.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 CAFIFDFH_00853 326425.lhe_1307 1.56e-161 452.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,3F564@33958|Lactobacillaceae 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm CAFIFDFH_00854 405566.lhv_1379 0.0 1732.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,3F478@33958|Lactobacillaceae 91061|Bacilli D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge CAFIFDFH_00855 326425.lhe_1305 3.45e-234 653.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,3F3YC@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N CAFIFDFH_00856 326425.lhe_1304 0.0 1001.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD2 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 CAFIFDFH_00857 326425.lhe_1303 1.38e-59 184.0 29P84@1|root,30A66@2|Bacteria,1U68Z@1239|Firmicutes,4IG04@91061|Bacilli,3F7C1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00858 326425.lhe_1302 0.0 900.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA32@91061|Bacilli,3FCAJ@33958|Lactobacillaceae 91061|Bacilli E amino acid ctrA - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 CAFIFDFH_00859 405566.lhv_1374 5.47e-164 459.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve CAFIFDFH_00860 326425.lhe_1301 1.17e-73 221.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli,3F7FG@33958|Lactobacillaceae 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 CAFIFDFH_00861 326425.lhe_1300 9.42e-290 797.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,3F40R@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB CAFIFDFH_00862 1033837.WANG_0417 2.36e-60 185.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 CAFIFDFH_00863 326425.lhe_1298 4.2e-122 348.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,3F74P@33958|Lactobacillaceae 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM CAFIFDFH_00864 405566.lhv_1369 2.41e-175 488.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,3F3NP@33958|Lactobacillaceae 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT CAFIFDFH_00865 1423748.BALB01000030_gene1896 2.28e-74 223.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,3F6K4@33958|Lactobacillaceae 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 CAFIFDFH_00866 405566.lhv_1366 3.71e-57 182.0 COG1573@1|root,COG1573@2|Bacteria,1V4M9@1239|Firmicutes,4HHJN@91061|Bacilli,3F4GW@33958|Lactobacillaceae 91061|Bacilli L Uracil-DNA glycosylase ung2 - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG CAFIFDFH_00867 326425.lhe_1294 3.86e-192 532.0 COG2755@1|root,COG2755@2|Bacteria,1V4VT@1239|Firmicutes,4HXCK@91061|Bacilli,3F4P8@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 CAFIFDFH_00868 405566.lhv_1364 2.07e-147 415.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,3F3JG@33958|Lactobacillaceae 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 CAFIFDFH_00869 326425.lhe_1292 3.19e-50 159.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,3F87S@33958|Lactobacillaceae 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 CAFIFDFH_00870 326425.lhe_1291 3.18e-41 135.0 COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,4HKMJ@91061|Bacilli,3F809@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0154) XK26_06720 - - ko:K09976 - - - - ko00000 - - - UPF0154 CAFIFDFH_00871 405566.lhv_1310 1.64e-136 387.0 COG0583@1|root,COG0583@2|Bacteria,1TT5B@1239|Firmicutes,4HK1M@91061|Bacilli,3F6BZ@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - LysR_substrate CAFIFDFH_00872 326425.lhe_1247 7.88e-27 98.2 2CETM@1|root,30AF4@2|Bacteria,1U6K3@1239|Firmicutes,4IGCS@91061|Bacilli,3F82Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00873 326425.lhe_1248 6.39e-280 765.0 COG4552@1|root,COG4552@2|Bacteria,1V7PR@1239|Firmicutes,4HV9V@91061|Bacilli,3FBA9@33958|Lactobacillaceae 91061|Bacilli S Sterol carrier protein domain - - - - - - - - - - - - Acetyltransf_9,SCP2_2 CAFIFDFH_00874 326425.lhe_1249 2.22e-125 357.0 COG3697@1|root,COG3697@2|Bacteria,1VB3E@1239|Firmicutes,4HMZ5@91061|Bacilli,3F74S@33958|Lactobacillaceae 91061|Bacilli HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase citX - 2.7.7.61 ko:K05964 ko02020,map02020 - R10706 - ko00000,ko00001,ko01000 - - - CitX CAFIFDFH_00875 1423748.BALB01000013_gene1303 5.35e-66 208.0 COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,4H9QD@91061|Bacilli,3F3T4@33958|Lactobacillaceae 91061|Bacilli E Belongs to the carbamate kinase family arcC - 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 - R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 - - - AA_kinase CAFIFDFH_00876 1423748.BALB01000013_gene1303 1.64e-44 152.0 COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,4H9QD@91061|Bacilli,3F3T4@33958|Lactobacillaceae 91061|Bacilli E Belongs to the carbamate kinase family arcC - 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 - R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 - - - AA_kinase CAFIFDFH_00877 1423748.BALB01000013_gene1302 2.33e-139 396.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,3F48K@33958|Lactobacillaceae 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N CAFIFDFH_00878 1033837.WANG_0462 4.02e-17 79.3 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,3F48K@33958|Lactobacillaceae 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N CAFIFDFH_00879 748671.LCRIS_01250 3.28e-111 330.0 COG2235@1|root,COG2235@2|Bacteria,1TQWS@1239|Firmicutes,4HCMG@91061|Bacilli,3F4VJ@33958|Lactobacillaceae 91061|Bacilli E Arginine arcA - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf CAFIFDFH_00880 1423748.BALB01000013_gene1301 1.99e-68 217.0 COG2235@1|root,COG2235@2|Bacteria,1TQWS@1239|Firmicutes,4HCMG@91061|Bacilli,3F4VJ@33958|Lactobacillaceae 91061|Bacilli E Arginine arcA - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf CAFIFDFH_00881 1423748.BALB01000013_gene1301 1.32e-33 124.0 COG2235@1|root,COG2235@2|Bacteria,1TQWS@1239|Firmicutes,4HCMG@91061|Bacilli,3F4VJ@33958|Lactobacillaceae 91061|Bacilli E Arginine arcA - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf CAFIFDFH_00882 405566.lhv_1322 3.44e-202 560.0 COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,4HBNZ@91061|Bacilli,3F4XG@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain lysR5 - - - - - - - - - - - HTH_1,LysR_substrate CAFIFDFH_00883 405566.lhv_1323 0.0 1431.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HVA4@91061|Bacilli,3F55J@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus - - - - - - - - - - - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase CAFIFDFH_00884 326425.lhe_1255 7.61e-111 319.0 29NWN@1|root,309UR@2|Bacteria,1U5RD@1239|Firmicutes,4IFFJ@91061|Bacilli,3F6D7@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - SLAP CAFIFDFH_00885 1423748.BALB01000013_gene1297 2.03e-41 145.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N CAFIFDFH_00886 405566.lhv_1325 1.55e-280 773.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N CAFIFDFH_00887 326425.lhe_1257 2.62e-196 543.0 COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli,3F5CA@33958|Lactobacillaceae 91061|Bacilli E Transfers an acetyl group from acetyl-CoA to metA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS CAFIFDFH_00888 405566.lhv_1327 3.35e-217 600.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,3F4VD@33958|Lactobacillaceae 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP CAFIFDFH_00889 326425.lhe_1259 2.41e-123 351.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli,3F4DB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran CAFIFDFH_00890 326425.lhe_1260 0.0 1514.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,3F42C@33958|Lactobacillaceae 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C CAFIFDFH_00891 326425.lhe_1261 2.47e-154 434.0 COG3764@1|root,COG3764@2|Bacteria,1V83Z@1239|Firmicutes,4HJV9@91061|Bacilli,3F54V@33958|Lactobacillaceae 91061|Bacilli M sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase CAFIFDFH_00892 326425.lhe_1262 0.0 1206.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,3F3Z1@33958|Lactobacillaceae 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C CAFIFDFH_00893 891391.LAC30SC_01195 1.29e-21 87.4 28QH1@1|root,2ZCZ3@2|Bacteria,1W1MV@1239|Firmicutes,4IG80@91061|Bacilli,3F7TZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00894 405566.lhv_0446 8.02e-30 112.0 COG3039@1|root,COG3039@2|Bacteria,1UZVA@1239|Firmicutes,4HH09@91061|Bacilli,3F4KP@33958|Lactobacillaceae 91061|Bacilli L An automated process has identified a potential problem with this gene model - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_3 CAFIFDFH_00895 525365.HMPREF0548_0665 3.83e-24 99.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,Hydrolase_4 CAFIFDFH_00896 326425.lhe_0593 1.62e-62 191.0 29PCT@1|root,30AB1@2|Bacteria,1U6EZ@1239|Firmicutes,4IG6T@91061|Bacilli,3F7RU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00897 405566.lhv_0663 2.81e-278 761.0 COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli,3F425@33958|Lactobacillaceae 91061|Bacilli I Hydroxymethylglutaryl-CoA synthase mvaS - 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 - - - HMG_CoA_synt_C,HMG_CoA_synt_N CAFIFDFH_00898 326425.lhe_0591 2.8e-277 759.0 COG1257@1|root,COG1257@2|Bacteria,1TPNY@1239|Firmicutes,4HBQ3@91061|Bacilli,3F3YY@33958|Lactobacillaceae 91061|Bacilli C Belongs to the HMG-CoA reductase family mvaA - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red CAFIFDFH_00899 326425.lhe_0590 6.11e-277 757.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,3F3Q5@33958|Lactobacillaceae 91061|Bacilli I Belongs to the thiolase family atoB - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red,Thiolase_C,Thiolase_N CAFIFDFH_00900 1033837.WANG_1686 2.99e-278 765.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F55P@33958|Lactobacillaceae 91061|Bacilli L transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon CAFIFDFH_00901 326425.lhe_0589 2.1e-215 594.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,3F45A@33958|Lactobacillaceae 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CAFIFDFH_00902 326425.lhe_0588 3.77e-197 549.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,3F4TC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0761 family rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB CAFIFDFH_00903 326425.lhe_0587 1.72e-211 582.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,3F3MK@33958|Lactobacillaceae 91061|Bacilli E Methionine Aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 CAFIFDFH_00904 326425.lhe_0586 3.48e-103 298.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli,3F6HY@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin ykuP - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 CAFIFDFH_00905 405566.lhv_0653 2.9e-117 336.0 COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,4HNK7@91061|Bacilli,3F4GH@33958|Lactobacillaceae 91061|Bacilli S Teichoic acid glycosylation protein gtcA1 - - - - - - - - - - - GtrA CAFIFDFH_00906 326425.lhe_0584 4.46e-276 754.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,3F3KQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 CAFIFDFH_00907 326425.lhe_0583 2.14e-35 120.0 29PJM@1|root,30AHS@2|Bacteria,1U6PN@1239|Firmicutes,4IGGM@91061|Bacilli,3F89D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00909 326425.lhe_0581 9.42e-314 855.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F4VG@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane chbC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC CAFIFDFH_00910 405566.lhv_0650 8.18e-269 739.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,3F4K8@33958|Lactobacillaceae 91061|Bacilli L DEAD DEAH box helicase yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C CAFIFDFH_00911 326425.lhe_0579 5.44e-165 461.0 COG3757@1|root,COG3757@2|Bacteria,1V484@1239|Firmicutes,4HQWA@91061|Bacilli,3F4K0@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 lys - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25 CAFIFDFH_00912 326425.lhe_0578 3.42e-297 813.0 COG0531@1|root,COG0531@2|Bacteria,1TQ48@1239|Firmicutes,4HBGT@91061|Bacilli,3F3YJ@33958|Lactobacillaceae 91061|Bacilli E amino acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 CAFIFDFH_00913 326425.lhe_0577 6.05e-133 377.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,3F56C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran CAFIFDFH_00914 326425.lhe_0576 0.0 866.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3TX@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain yhdP - - - - - - - - - - - CBS,CorC_HlyC,DUF21 CAFIFDFH_00915 1423748.BALB01000004_gene580 9.34e-65 201.0 COG0778@1|root,COG0778@2|Bacteria,1V6AG@1239|Firmicutes,4HN5N@91061|Bacilli,3F6YM@33958|Lactobacillaceae 91061|Bacilli C nitroreductase - - - - - - - - - - - - Nitroreductase CAFIFDFH_00916 1423748.BALB01000004_gene580 3.42e-19 82.8 COG0778@1|root,COG0778@2|Bacteria,1V6AG@1239|Firmicutes,4HN5N@91061|Bacilli,3F6YM@33958|Lactobacillaceae 91061|Bacilli C nitroreductase - - - - - - - - - - - - Nitroreductase CAFIFDFH_00917 405566.lhv_2311 1.36e-44 145.0 29PEW@1|root,30AD2@2|Bacteria,1U6H9@1239|Firmicutes,4IG9K@91061|Bacilli,3F7X8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00918 1423754.BALY01000006_gene1368 4.58e-32 119.0 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,4HD6M@91061|Bacilli,3F43M@33958|Lactobacillaceae 91061|Bacilli L hmm pf00665 - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 CAFIFDFH_00919 1423754.BALY01000006_gene1368 5.33e-183 512.0 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,4HD6M@91061|Bacilli,3F43M@33958|Lactobacillaceae 91061|Bacilli L hmm pf00665 - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 CAFIFDFH_00920 525365.HMPREF0548_1650 7.34e-55 177.0 COG2963@1|root,COG2963@2|Bacteria,1V1QC@1239|Firmicutes,4HH7E@91061|Bacilli,3F5BG@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain - - - - - - - - - - - - HTH_28,HTH_Tnp_1 CAFIFDFH_00921 525365.HMPREF0548_1650 1.31e-71 220.0 COG2963@1|root,COG2963@2|Bacteria,1V1QC@1239|Firmicutes,4HH7E@91061|Bacilli,3F5BG@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain - - - - - - - - - - - - HTH_28,HTH_Tnp_1 CAFIFDFH_00922 326425.lhe_1105 3.07e-206 570.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HFBQ@91061|Bacilli,3F54P@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein cjaA - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 CAFIFDFH_00923 326425.lhe_1104 1.39e-173 484.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4HDK7@91061|Bacilli,3FC3P@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran CAFIFDFH_00924 326425.lhe_1103 1.39e-121 351.0 COG0765@1|root,COG0765@2|Bacteria,1TR7R@1239|Firmicutes,4HGVA@91061|Bacilli,3F45E@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnP7 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 CAFIFDFH_00925 1033837.WANG_1274 1.32e-144 409.0 COG0765@1|root,COG0765@2|Bacteria,1TRU3@1239|Firmicutes,4HGE1@91061|Bacilli,3F3XD@33958|Lactobacillaceae 91061|Bacilli P ABC transporter, permease protein glnP9 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 CAFIFDFH_00926 326425.lhe_1101 2.09e-91 267.0 COG0789@1|root,COG0789@2|Bacteria,1VAAP@1239|Firmicutes,4HKZ9@91061|Bacilli,3F6JI@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance adhR - - ko:K21745 - - - - ko00000,ko03000 - - - MerR,MerR_1 CAFIFDFH_00927 1033837.WANG_1276 2.03e-34 119.0 COG4334@1|root,COG4334@2|Bacteria,1VBEN@1239|Firmicutes,4HM8H@91061|Bacilli,3F75W@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2255) - - - - - - - - - - - - DUF2255 CAFIFDFH_00928 326425.lhe_1099 6.99e-99 286.0 COG3741@1|root,COG3741@2|Bacteria,1V6B3@1239|Firmicutes,4HQ4E@91061|Bacilli,3F6V6@33958|Lactobacillaceae 91061|Bacilli E N-formylglutamate amidohydrolase hutG - 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - FGase CAFIFDFH_00929 326425.lhe_1098 2.7e-126 359.0 COG1051@1|root,COG1051@2|Bacteria,1VFNI@1239|Firmicutes,4HQPJ@91061|Bacilli,3F4CG@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - 3.6.1.67 ko:K19965 ko00790,map00790 M00126 R04638 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NUDIX CAFIFDFH_00930 326425.lhe_1097 5.22e-255 700.0 COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,3F4SS@33958|Lactobacillaceae 91061|Bacilli H dihydropteroate synthase folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind CAFIFDFH_00931 353496.LBU_0194 1.87e-316 862.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,3F3ZR@33958|Lactobacillaceae 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M CAFIFDFH_00932 353496.LBU_0193 2.51e-259 710.0 COG0302@1|root,COG0801@1|root,COG0302@2|Bacteria,COG0801@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli,3F4A0@33958|Lactobacillaceae 91061|Bacilli F GTP cyclohydrolase 1 folE - 2.7.6.3,3.5.4.16 ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R03503,R04639,R05046,R05048 RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI,HPPK CAFIFDFH_00933 326425.lhe_1094 8.76e-75 224.0 COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli,3F7N6@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB CAFIFDFH_00934 326425.lhe_1092 1.35e-161 451.0 COG2231@1|root,COG2231@2|Bacteria,1V4SG@1239|Firmicutes,4HI5U@91061|Bacilli,3F62T@33958|Lactobacillaceae 91061|Bacilli L Base excision DNA repair protein, HhH-GPD family nth2 - - ko:K07457 - - - - ko00000 - - - HhH-GPD CAFIFDFH_00935 326425.lhe_1091 1.42e-57 178.0 29PX4@1|root,30AVF@2|Bacteria,1U75H@1239|Firmicutes,4IH06@91061|Bacilli,3F907@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00936 326425.lhe_1090 7.65e-101 292.0 COG3279@1|root,COG3279@2|Bacteria,1U5WZ@1239|Firmicutes,4IFKG@91061|Bacilli,3F6MT@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR CAFIFDFH_00937 326425.lhe_1089 7.5e-86 253.0 29P3F@1|root,30A1N@2|Bacteria,1U62T@1239|Firmicutes,4IFRY@91061|Bacilli,3F6WA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 CAFIFDFH_00938 405566.lhv_1196 2.76e-115 330.0 COG0454@1|root,COG0454@2|Bacteria,1UHPQ@1239|Firmicutes,4IS5I@91061|Bacilli,3FBT6@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 CAFIFDFH_00939 405566.lhv_1195 7.54e-174 496.0 2A8RI@1|root,30XU8@2|Bacteria,1VQ4B@1239|Firmicutes,4IJHJ@91061|Bacilli,3F4H8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00940 405566.lhv_1195 9.52e-58 192.0 2A8RI@1|root,30XU8@2|Bacteria,1VQ4B@1239|Firmicutes,4IJHJ@91061|Bacilli,3F4H8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00941 405566.lhv_1193 0.0 1744.0 COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli,3F4BB@33958|Lactobacillaceae 91061|Bacilli H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase CAFIFDFH_00942 326425.lhe_0065 1.51e-176 491.0 COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,3F4NI@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase ysaA - 3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 - - - HAD_2 CAFIFDFH_00943 326425.lhe_0064 3.66e-227 627.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F462@33958|Lactobacillaceae 91061|Bacilli S ABC transporter ABC-SBP - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind CAFIFDFH_00944 1033837.WANG_1617 1.12e-166 471.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,3F40J@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family XK27_08840 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 CAFIFDFH_00945 326425.lhe_0062 4.47e-178 496.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,3F3NW@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein XK27_08845 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran CAFIFDFH_00946 1033837.WANG_1572 5.9e-69 209.0 2BZTJ@1|root,30A2T@2|Bacteria,1U644@1239|Firmicutes,4IFTP@91061|Bacilli,3F6ZQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00947 326425.lhe_0060 4.09e-23 89.4 2AR30@1|root,30ATE@2|Bacteria,1U731@1239|Firmicutes,4IGXJ@91061|Bacilli,3F8WS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00948 326425.lhe_0059 7.94e-134 379.0 COG2755@1|root,COG2755@2|Bacteria,1VAT2@1239|Firmicutes,4HKYJ@91061|Bacilli,3F5TI@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2 CAFIFDFH_00949 405566.lhv_0043 8.49e-224 619.0 COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,3F46E@33958|Lactobacillaceae 91061|Bacilli K AI-2E family transporter ydbI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport CAFIFDFH_00950 326425.lhe_0057 0.0 1503.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,4HFF1@91061|Bacilli,3F3VU@33958|Lactobacillaceae 91061|Bacilli F ribonucleoside-triphosphate reductase activity rtpR - 1.17.4.2 ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02014,R02020,R02022,R02023,R04315 RC00013,RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC CAFIFDFH_00951 326425.lhe_0056 8.34e-77 230.0 2DNM7@1|root,32Y2X@2|Bacteria,1VF26@1239|Firmicutes,4HP82@91061|Bacilli,3F6AM@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4430) - - - - - - - - - - - - DUF4430 CAFIFDFH_00952 326425.lhe_0055 9.05e-114 327.0 COG4720@1|root,COG4720@2|Bacteria,1V5GD@1239|Firmicutes,4HI8Y@91061|Bacilli,3F5H7@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF-ribofla_trS,ECF_trnsprt CAFIFDFH_00953 326425.lhe_0054 1.55e-129 368.0 COG2096@1|root,COG2096@2|Bacteria,1UZ2W@1239|Firmicutes,4HF48@91061|Bacilli,3F6MY@33958|Lactobacillaceae 91061|Bacilli S Cob(I)alamin adenosyltransferase - - - - - - - - - - - - Cob_adeno_trans CAFIFDFH_00954 405566.lhv_0038 4.51e-189 524.0 COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,4HK25@91061|Bacilli,3F3MV@33958|Lactobacillaceae 91061|Bacilli S Putative ABC-transporter type IV - - - - - - - - - - - - ABC_trans_CmpB CAFIFDFH_00955 326425.lhe_0051 2.26e-305 835.0 29P37@1|root,30A1D@2|Bacteria,1U62D@1239|Firmicutes,4IFRD@91061|Bacilli,3F6V7@33958|Lactobacillaceae 91061|Bacilli S LPXTG cell wall anchor motif - - - - - - - - - - - - Gram_pos_anchor CAFIFDFH_00956 525365.HMPREF0548_1318 2.75e-194 548.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase - - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 CAFIFDFH_00957 525365.HMPREF0548_1318 2.54e-48 166.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase - - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 CAFIFDFH_00958 405566.lhv_0031 0.0 880.0 COG1715@1|root,COG1715@2|Bacteria,1VI0R@1239|Firmicutes,4HPTI@91061|Bacilli,3F8WY@33958|Lactobacillaceae 91061|Bacilli V Restriction endonuclease - - - - - - - - - - - - Mrr_cat CAFIFDFH_00959 326425.lhe_0048 1.04e-136 387.0 COG1309@1|root,COG1309@2|Bacteria,1V6JC@1239|Firmicutes,4IF0F@91061|Bacilli,3F58C@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CAFIFDFH_00960 525365.HMPREF0548_1143 1.37e-28 112.0 COG0846@1|root,COG0846@2|Bacteria,1V192@1239|Firmicutes,4IJ3S@91061|Bacilli,3F5GG@33958|Lactobacillaceae 91061|Bacilli K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - - - - - - - - - - - CAFIFDFH_00961 326425.lhe_0046 5.41e-100 296.0 COG0846@1|root,COG0846@2|Bacteria,1V192@1239|Firmicutes,4IJ3S@91061|Bacilli,3F5GG@33958|Lactobacillaceae 91061|Bacilli K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - ko:K09705 - - - - ko00000 - - - - CAFIFDFH_00962 326425.lhe_0046 4.86e-86 258.0 COG0846@1|root,COG0846@2|Bacteria,1V192@1239|Firmicutes,4IJ3S@91061|Bacilli,3F5GG@33958|Lactobacillaceae 91061|Bacilli K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - ko:K09705 - - - - ko00000 - - - - CAFIFDFH_00963 326425.lhe_1165 2.32e-103 302.0 2DKIE@1|root,309JQ@2|Bacteria,1U58N@1239|Firmicutes,4IEZY@91061|Bacilli,3F55M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00964 405566.lhv_1287 2e-182 509.0 29NT4@1|root,30GID@2|Bacteria,1UG47@1239|Firmicutes,4IF33@91061|Bacilli,3F5H9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00965 405566.lhv_1288 8.63e-190 528.0 29NT4@1|root,309R6@2|Bacteria,1U5IX@1239|Firmicutes,4HZ1H@91061|Bacilli,3F624@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00966 326425.lhe_1168 3.65e-159 447.0 COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HG6U@91061|Bacilli,3F4GA@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CAFIFDFH_00967 326425.lhe_1169 7.06e-81 239.0 COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,4HPK4@91061|Bacilli,3F6GC@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, GntR family lexA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR CAFIFDFH_00968 326425.lhe_1170 2.1e-309 842.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,3F45V@33958|Lactobacillaceae 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M42 CAFIFDFH_00969 326425.lhe_1171 4.9e-197 545.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,3F3ZD@33958|Lactobacillaceae 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 CAFIFDFH_00970 405566.lhv_1293 3.68e-160 449.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,3F4GT@33958|Lactobacillaceae 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK CAFIFDFH_00971 525365.HMPREF0548_0065 2.69e-40 136.0 COG1051@1|root,COG1051@2|Bacteria,1V6PF@1239|Firmicutes,4HKTF@91061|Bacilli,3F66W@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX CAFIFDFH_00972 326425.lhe_1174 1.99e-159 446.0 2DVJ8@1|root,33W59@2|Bacteria,1UI90@1239|Firmicutes,4HD3X@91061|Bacilli,3F3K4@33958|Lactobacillaceae 91061|Bacilli S Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 CAFIFDFH_00973 326425.lhe_1175 8.62e-253 695.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,3F4CF@33958|Lactobacillaceae 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 CAFIFDFH_00974 326425.lhe_1176 0.0 1203.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,3F3N1@33958|Lactobacillaceae 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 CAFIFDFH_00975 326425.lhe_1177 0.0 1330.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,3F4G8@33958|Lactobacillaceae 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f CAFIFDFH_00976 326425.lhe_1178 2.22e-229 630.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,3F3T8@33958|Lactobacillaceae 91061|Bacilli J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e CAFIFDFH_00977 326425.lhe_1179 1.62e-174 487.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,3F56P@33958|Lactobacillaceae 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N CAFIFDFH_00978 326425.lhe_1180 6.28e-218 601.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,3F3WQ@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 CAFIFDFH_00979 326425.lhe_1181 2.62e-131 371.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,3F516@33958|Lactobacillaceae 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 CAFIFDFH_00980 326425.lhe_1182 2.03e-223 616.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,3F4E7@33958|Lactobacillaceae 91061|Bacilli T phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH CAFIFDFH_00981 326425.lhe_1183 5.12e-91 267.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,3F6I0@33958|Lactobacillaceae 91061|Bacilli S YqeY-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY CAFIFDFH_00982 1033837.WANG_0480 4.83e-30 106.0 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli,3F81Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 CAFIFDFH_00983 1408303.JNJJ01000011_gene1460 9.8e-51 178.0 COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HCW0@91061|Bacilli,1ZFI5@1386|Bacillus 91061|Bacilli S COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 CAFIFDFH_00984 525365.HMPREF0548_1894 1.41e-51 171.0 COG3547@1|root,COG3547@2|Bacteria,1TP4A@1239|Firmicutes,4HDAB@91061|Bacilli,3F40X@33958|Lactobacillaceae 91061|Bacilli L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 CAFIFDFH_00985 1423754.BALY01000060_gene694 1.68e-09 57.4 COG3547@1|root,COG3547@2|Bacteria,1TP4A@1239|Firmicutes,4HDAB@91061|Bacilli,3F40X@33958|Lactobacillaceae 91061|Bacilli L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 CAFIFDFH_00986 862517.HMPREF9225_0211 5.17e-142 434.0 COG3344@1|root,COG3344@2|Bacteria 2|Bacteria L reverse transcriptase - - - - - - - - - - - - RVT_1 CAFIFDFH_00987 525365.HMPREF0548_1925 3.17e-34 124.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,3F45A@33958|Lactobacillaceae 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CAFIFDFH_00989 525365.HMPREF0548_1642 3.29e-279 763.0 COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,4ISNQ@91061|Bacilli,3F5ZT@33958|Lactobacillaceae 91061|Bacilli KQ helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1,Methyltransf_11,Methyltransf_25,TipAS CAFIFDFH_00990 326425.lhe_0427 2.33e-267 729.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,3F3R6@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd CAFIFDFH_00991 326425.lhe_0428 1.31e-211 584.0 COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli,3F4F8@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CAFIFDFH_00992 748671.LCRIS_01734 1.93e-149 419.0 COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,4HFQB@91061|Bacilli,3F4FN@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom CAFIFDFH_00993 326425.lhe_0430 1.53e-243 668.0 COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,3F4QS@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind CAFIFDFH_00994 326425.lhe_0435 6.38e-08 55.5 29QEJ@1|root,30BDX@2|Bacteria,1U7Z5@1239|Firmicutes,4IHWH@91061|Bacilli,3FACF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_00995 405566.lhv_1786 0.0 956.0 COG0531@1|root,COG0531@2|Bacteria,1UYSD@1239|Firmicutes,4IPMN@91061|Bacilli,3F48U@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 CAFIFDFH_00996 326425.lhe_0437 0.0 1421.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,3F3TV@33958|Lactobacillaceae 91061|Bacilli E Orn/Lys/Arg decarboxylase, C-terminal domain speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.17,4.1.1.18,4.1.1.19 ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 M00133,M00134 R00462,R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C CAFIFDFH_00997 326425.lhe_0438 1.21e-211 584.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,3F45A@33958|Lactobacillaceae 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CAFIFDFH_00998 272621.LBA1391 4.75e-67 212.0 COG5549@1|root,COG5549@2|Bacteria,1U6CU@1239|Firmicutes,4IG4J@91061|Bacilli,3F7MF@33958|Lactobacillaceae 91061|Bacilli O Matrixin - - - - - - - - - - - - Peptidase_M10 CAFIFDFH_00999 525365.HMPREF0548_0217 1.89e-208 583.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F587@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC CAFIFDFH_01000 525365.HMPREF0548_0217 2.21e-52 176.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F587@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC CAFIFDFH_01001 326425.lhe_1371 0.0 1585.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase yoaB - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 CAFIFDFH_01002 1423748.BALB01000022_gene1702 2.41e-144 412.0 COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli,3F4AJ@33958|Lactobacillaceae 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufQ - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 CAFIFDFH_01003 525365.HMPREF0548_0252 5.91e-39 139.0 COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli,3F4AJ@33958|Lactobacillaceae 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufQ - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 CAFIFDFH_01004 1423748.BALB01000022_gene1701 4.45e-73 231.0 COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli,3F59X@33958|Lactobacillaceae 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family mglC - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 CAFIFDFH_01006 1033837.WANG_0225 8.52e-29 104.0 2DKPC@1|root,30A7C@2|Bacteria,1U6AB@1239|Firmicutes,4IG1M@91061|Bacilli,3F7FJ@33958|Lactobacillaceae 91061|Bacilli S RelB antitoxin - - - ko:K18918 - - - - ko00000,ko02048,ko03000 - - - RelB CAFIFDFH_01007 326425.lhe_1368 2.34e-148 417.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,3F487@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran CAFIFDFH_01008 326425.lhe_1367 2.69e-165 462.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,3F47Y@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase CAFIFDFH_01009 405566.lhv_2937 3.21e-214 592.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,3F4PJ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh CAFIFDFH_01010 405566.lhv_1447 3.53e-123 351.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,3F4SR@33958|Lactobacillaceae 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran CAFIFDFH_01011 405566.lhv_1446 3.68e-230 633.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,3F4BQ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N CAFIFDFH_01012 405566.lhv_1445 2.9e-313 852.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,3F3S3@33958|Lactobacillaceae 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 CAFIFDFH_01013 353496.LBU_1726 1.21e-268 734.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,3F43R@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase CAFIFDFH_01014 353496.LBU_1725 0.0 2081.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS CAFIFDFH_01015 326425.lhe_0295 4.63e-119 341.0 COG1268@1|root,COG1268@2|Bacteria,1V9T0@1239|Firmicutes,4HK0R@91061|Bacilli,3FBMX@33958|Lactobacillaceae 91061|Bacilli S BioY family bioY - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY CAFIFDFH_01016 326425.lhe_0294 1.3e-240 660.0 COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,3F5HY@33958|Lactobacillaceae 91061|Bacilli H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 CAFIFDFH_01017 405566.lhv_1922 2.68e-174 486.0 COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,3F4AQ@33958|Lactobacillaceae 91061|Bacilli I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CAFIFDFH_01018 405566.lhv_1923 2.6e-183 509.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,3F496@33958|Lactobacillaceae 91061|Bacilli I alpha subunit accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA CAFIFDFH_01019 405566.lhv_1924 1.78e-202 560.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,3F3T6@33958|Lactobacillaceae 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans CAFIFDFH_01020 326425.lhe_0290 0.0 908.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,3F3PT@33958|Lactobacillaceae 91061|Bacilli I Acetyl-CoA carboxylase biotin carboxylase subunit accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 CAFIFDFH_01021 326425.lhe_0289 6.93e-96 279.0 COG0764@1|root,COG0764@2|Bacteria,1VXBZ@1239|Firmicutes,4HXVK@91061|Bacilli,3F6TF@33958|Lactobacillaceae 91061|Bacilli I FabA-like domain fabZ2 - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA CAFIFDFH_01022 405566.lhv_1927 5.23e-102 296.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,3F7M1@33958|Lactobacillaceae 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl CAFIFDFH_01023 326425.lhe_0287 7.69e-294 802.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,3F51H@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt CAFIFDFH_01024 405566.lhv_1929 5.38e-165 462.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,3F4RI@33958|Lactobacillaceae 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 CAFIFDFH_01025 405566.lhv_1930 1.22e-217 600.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,3F3W9@33958|Lactobacillaceae 91061|Bacilli I Malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 CAFIFDFH_01026 326425.lhe_0284 6.25e-47 150.0 COG0236@1|root,COG0236@2|Bacteria,1VGIY@1239|Firmicutes,4HP0V@91061|Bacilli,3F7ZJ@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CAFIFDFH_01027 326425.lhe_0283 3.15e-231 637.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,3F3XP@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C CAFIFDFH_01028 326425.lhe_0282 3.55e-104 301.0 COG1846@1|root,COG1846@2|Bacteria,1VCUU@1239|Firmicutes,4HIUM@91061|Bacilli,3FC7K@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 CAFIFDFH_01029 1033837.WANG_1763 5.77e-102 295.0 COG0764@1|root,COG0764@2|Bacteria,1V3UN@1239|Firmicutes,4HHYD@91061|Bacilli,3FCD6@33958|Lactobacillaceae 91061|Bacilli I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA CAFIFDFH_01030 326425.lhe_0280 1.55e-99 296.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,3F45P@33958|Lactobacillaceae 91061|Bacilli F pyrimidine-nucleoside phosphorylase pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C CAFIFDFH_01031 1033837.WANG_1761 5.83e-121 357.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,3F45P@33958|Lactobacillaceae 91061|Bacilli F pyrimidine-nucleoside phosphorylase pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C CAFIFDFH_01032 1033837.WANG_1747 3.73e-40 134.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc CAFIFDFH_01033 326425.lhe_0278 1.08e-130 371.0 COG1961@1|root,COG1961@2|Bacteria,1V51N@1239|Firmicutes,4HDX2@91061|Bacilli,3F51V@33958|Lactobacillaceae 91061|Bacilli L Resolvase, N terminal domain - GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - - - - - - - - - - Resolvase CAFIFDFH_01034 1423732.BALS01000152_gene507 8.38e-83 254.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 CAFIFDFH_01035 405566.lhv_1940 2.07e-204 566.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,3F4K2@33958|Lactobacillaceae 91061|Bacilli U sugar transport glcU GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659 - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport CAFIFDFH_01036 1033837.WANG_0179 2e-78 266.0 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal CAFIFDFH_01037 405566.lhv_0973 8.63e-175 493.0 29W6X@1|root,30HS4@2|Bacteria,1UHXX@1239|Firmicutes,4ISAB@91061|Bacilli,3F8TA@33958|Lactobacillaceae 91061|Bacilli S YSIRK type signal peptide - - - - - - - - - - - - YSIRK_signal CAFIFDFH_01038 272621.LBA0909 4.72e-16 77.4 COG4932@1|root,COG4932@2|Bacteria,1UJ2C@1239|Firmicutes,4ISZG@91061|Bacilli,3FBTV@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - - CAFIFDFH_01040 272621.LBA0909 4.04e-70 229.0 COG4932@1|root,COG4932@2|Bacteria,1UJ2C@1239|Firmicutes,4ISZG@91061|Bacilli,3FBTV@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - - CAFIFDFH_01042 326425.lhe_0911 0.0 907.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,3F3KJ@33958|Lactobacillaceae 91061|Bacilli C FAD binding domain frdA - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2 CAFIFDFH_01043 405566.lhv_0968 0.0 919.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,3F3K0@33958|Lactobacillaceae 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 CAFIFDFH_01044 326425.lhe_0909 4.08e-47 150.0 29PZQ@1|root,30AY5@2|Bacteria,1U797@1239|Firmicutes,4IH43@91061|Bacilli,3F957@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01045 525365.HMPREF0548_1721 6.98e-82 248.0 COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,4HCSJ@91061|Bacilli,3F51K@33958|Lactobacillaceae 91061|Bacilli S cog cog1373 - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CAFIFDFH_01046 1423767.BALU01000004_gene1377 8.07e-123 362.0 COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,4HCSJ@91061|Bacilli,3F51K@33958|Lactobacillaceae 91061|Bacilli S cog cog1373 - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CAFIFDFH_01047 326425.lhe_0907 4.88e-131 375.0 COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,4HBEV@91061|Bacilli,3F48A@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 CAFIFDFH_01048 326425.lhe_0906 2.94e-240 662.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,3F3U5@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL CAFIFDFH_01049 405566.lhv_0960 5.32e-207 572.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3F3WP@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 CAFIFDFH_01050 326425.lhe_0904 0.0 907.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9ZI@91061|Bacilli,3F4Y1@33958|Lactobacillaceae 91061|Bacilli P E1-E2 ATPase aha1 - - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase CAFIFDFH_01051 326425.lhe_0904 2.46e-174 509.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9ZI@91061|Bacilli,3F4Y1@33958|Lactobacillaceae 91061|Bacilli P E1-E2 ATPase aha1 - - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase CAFIFDFH_01052 1423748.BALB01000023_gene1731 8.41e-21 85.9 COG2944@1|root,COG2944@2|Bacteria 2|Bacteria K sequence-specific DNA binding ps301 - - - - - - - - - - - DUF4065,HTH_3,MqsA_antitoxin CAFIFDFH_01053 326425.lhe_0901 6.83e-236 656.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,3F3SB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt CAFIFDFH_01055 326425.lhe_0788 8.71e-278 760.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,3F4J4@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE CAFIFDFH_01056 326425.lhe_0787 8.85e-47 150.0 29FEW@1|root,302CK@2|Bacteria,1U6BQ@1239|Firmicutes,4IG3B@91061|Bacilli,3F7J3@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2969) - - - - - - - - - - - - DUF2969 CAFIFDFH_01057 405566.lhv_2403 1.12e-68 207.0 COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli,3F7H1@33958|Lactobacillaceae 91061|Bacilli S Could be involved in insertion of integral membrane proteins into the membrane ytjA - - ko:K08998 - - - - ko00000 - - - Haemolytic CAFIFDFH_01058 326425.lhe_0785 7.12e-229 631.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F463@33958|Lactobacillaceae 91061|Bacilli D Cell shape determining protein MreB Mrl mbl - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl CAFIFDFH_01059 405566.lhv_2402 4.22e-41 135.0 COG4836@1|root,COG4836@2|Bacteria,1U2FQ@1239|Firmicutes,4HNZX@91061|Bacilli,3F831@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1146) - - - - - - - - - - - - DUF1146 CAFIFDFH_01060 326425.lhe_0783 1.21e-93 274.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,3F6I6@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N CAFIFDFH_01061 326425.lhe_0782 0.0 889.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,3F3TF@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N CAFIFDFH_01062 326425.lhe_0781 6.03e-221 610.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,3F40E@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt CAFIFDFH_01063 405566.lhv_0810 0.0 975.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,3F3R4@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N CAFIFDFH_01064 326425.lhe_0779 4.8e-122 348.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,3F5TZ@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP CAFIFDFH_01065 1423748.BALB01000001_gene98 7.87e-92 271.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,3F5M8@33958|Lactobacillaceae 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B CAFIFDFH_01066 326425.lhe_0777 2.16e-39 131.0 COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli,3F82A@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C CAFIFDFH_01067 326425.lhe_0776 2.91e-166 465.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,3F3RE@33958|Lactobacillaceae 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A CAFIFDFH_01068 326425.lhe_0775 1.3e-146 413.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,3F4M0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase CAFIFDFH_01069 326425.lhe_0774 1.07e-241 664.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,3F3T1@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC CAFIFDFH_01070 326425.lhe_0773 1.03e-201 558.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,3F460@33958|Lactobacillaceae 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS CAFIFDFH_01071 326425.lhe_0772 5.18e-234 647.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,3F3Q0@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 CAFIFDFH_01072 326425.lhe_0771 1.21e-146 412.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,3F4UE@33958|Lactobacillaceae 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK CAFIFDFH_01073 405566.lhv_0800 0.0 897.0 COG0770@1|root,COG0770@2|Bacteria,1TRG9@1239|Firmicutes,4HAMY@91061|Bacilli,3FBS5@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF1727) murE2 - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - DUF1727,Mur_ligase_M CAFIFDFH_01076 326425.lhe_0757 1.22e-249 684.0 COG1680@1|root,COG1680@2|Bacteria,1TNZX@1239|Firmicutes,4IPJT@91061|Bacilli,3F3WZ@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase ampC - - - - - - - - - - - Beta-lactamase CAFIFDFH_01077 326425.lhe_0818 1.09e-18 77.0 29GVY@1|root,303TQ@2|Bacteria,1TV7P@1239|Firmicutes,4I8MD@91061|Bacilli,3F8AT@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF4044) - - - - - - - - - - - - DUF4044 CAFIFDFH_01078 326425.lhe_0819 4.46e-72 216.0 2A5PG@1|root,30UEB@2|Bacteria,1U6DY@1239|Firmicutes,4IG5S@91061|Bacilli,3F7PE@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3397) - - - - - - - - - - - - DUF3397 CAFIFDFH_01079 326425.lhe_0820 6.32e-99 287.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,3F6K3@33958|Lactobacillaceae 91061|Bacilli K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ CAFIFDFH_01080 326425.lhe_0821 1.7e-234 645.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,3F3MF@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 CAFIFDFH_01081 326425.lhe_0822 3.79e-71 215.0 COG4839@1|root,COG4839@2|Bacteria,1VCE5@1239|Firmicutes,4HM4W@91061|Bacilli,3F6KG@33958|Lactobacillaceae 91061|Bacilli D Cell division protein FtsL ftsL - - - - - - - - - - - DivIC CAFIFDFH_01082 272621.LBA0805 0.0 1083.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,3F47N@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase CAFIFDFH_01083 1423748.BALB01000001_gene45 1.67e-57 194.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,3F47N@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase CAFIFDFH_01084 405566.lhv_0854 3.96e-227 626.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,3F3YP@33958|Lactobacillaceae 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 CAFIFDFH_01085 326425.lhe_0825 0.0 900.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,3F49W@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M CAFIFDFH_01086 405566.lhv_0856 6e-268 733.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,3F4FW@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 CAFIFDFH_01087 405566.lhv_0857 1.28e-193 538.0 COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,3F406@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 CAFIFDFH_01088 405566.lhv_0858 1.14e-299 820.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,3F413@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA CAFIFDFH_01089 326425.lhe_0829 6.3e-267 736.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,3F4V1@33958|Lactobacillaceae 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin CAFIFDFH_01090 326425.lhe_0830 2.88e-96 280.0 COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,4HKIC@91061|Bacilli,3F7MQ@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF CAFIFDFH_01091 326425.lhe_0831 5.07e-62 190.0 COG0762@1|root,COG0762@2|Bacteria,1U6JG@1239|Firmicutes,4IGBY@91061|Bacilli,3F818@33958|Lactobacillaceae 91061|Bacilli S YGGT family yggT - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT CAFIFDFH_01092 326425.lhe_0832 4.01e-192 533.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,3F48W@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein ylmH - - - - - - - - - - - S4 CAFIFDFH_01093 326425.lhe_0833 2.28e-161 455.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,3F4IN@33958|Lactobacillaceae 91061|Bacilli D DivIVA domain protein divIVA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA CAFIFDFH_01094 405566.lhv_0863 0.0 1896.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,3F3X4@33958|Lactobacillaceae 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS CAFIFDFH_01095 1423748.BALB01000001_gene32 1.15e-43 141.0 COG1278@1|root,COG1278@2|Bacteria,1U6DB@1239|Firmicutes,4IG52@91061|Bacilli,3F7NC@33958|Lactobacillaceae 91061|Bacilli K 'Cold-shock' DNA-binding domain cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD CAFIFDFH_01096 326425.lhe_0836 6.29e-135 382.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,3F53J@33958|Lactobacillaceae 91061|Bacilli L ADP-ribose pyrophosphatase nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX CAFIFDFH_01097 326425.lhe_0837 9.02e-57 177.0 2B5KT@1|root,31YFV@2|Bacteria,1U6T4@1239|Firmicutes,4IGKV@91061|Bacilli,3F8FY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01098 326425.lhe_0838 2.8e-161 452.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,3F4HE@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 CAFIFDFH_01099 326425.lhe_0839 5.65e-277 757.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,3F3RF@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 CAFIFDFH_01100 326425.lhe_0840 2.01e-74 223.0 2DHWG@1|root,32U9W@2|Bacteria,1VDSF@1239|Firmicutes,4HP9N@91061|Bacilli,3F7E3@33958|Lactobacillaceae 91061|Bacilli S Putative amino acid metabolism XK27_04120 - - - - - - - - - - - DUF1831 CAFIFDFH_01101 326425.lhe_0841 1.14e-280 766.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,3F4N5@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans CAFIFDFH_01102 326425.lhe_0842 5.5e-162 452.0 COG0406@1|root,COG0406@2|Bacteria,1V7EZ@1239|Firmicutes,4HJCK@91061|Bacilli,3FBD9@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family pgm - - - - - - - - - - - His_Phos_1 CAFIFDFH_01103 405566.lhv_0872 4.48e-145 409.0 COG0457@1|root,COG0457@2|Bacteria,1VFGR@1239|Firmicutes,4IBSH@91061|Bacilli,3F4MD@33958|Lactobacillaceae 91061|Bacilli S repeat protein - - - - - - - - - - - - TPR_12,TPR_16,TPR_19,TPR_2,TPR_8 CAFIFDFH_01104 326425.lhe_0844 0.0 1512.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,3F44X@33958|Lactobacillaceae 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 CAFIFDFH_01105 1423748.BALB01000001_gene22 4.67e-105 310.0 COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,4HBUD@91061|Bacilli,3F5GQ@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat CAFIFDFH_01107 1423748.BALB01000001_gene22 1.83e-37 134.0 COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,4HBUD@91061|Bacilli,3F5GQ@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat CAFIFDFH_01108 326425.lhe_0846 0.0 1099.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3TT@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL CAFIFDFH_01109 1033837.WANG_0819 9e-46 147.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,3F807@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 CAFIFDFH_01110 326425.lhe_0848 1.96e-131 372.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HH0G@91061|Bacilli,3F3YH@33958|Lactobacillaceae 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase CAFIFDFH_01111 326425.lhe_0849 0.0 1209.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,3F3UK@33958|Lactobacillaceae 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 CAFIFDFH_01112 326425.lhe_0850 1.16e-264 727.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,3F4IK@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE CAFIFDFH_01113 326425.lhe_0851 1.72e-71 215.0 COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli,3F70V@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2129) ylbG - - - - - - - - - - - DUF2129 CAFIFDFH_01114 326425.lhe_0852 6.08e-125 356.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,3F505@33958|Lactobacillaceae 91061|Bacilli L RNA methyltransferase, RsmD family rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 CAFIFDFH_01115 326425.lhe_0853 3.35e-111 320.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,3FCD3@33958|Lactobacillaceae 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like CAFIFDFH_01116 405566.lhv_0887 6.48e-244 670.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,3F4KY@33958|Lactobacillaceae 91061|Bacilli T Belongs to the peptidase S16 family lon - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 CAFIFDFH_01117 326425.lhe_0855 5.44e-127 365.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,3F7NP@33958|Lactobacillaceae 91061|Bacilli L Competence protein ComEA comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB CAFIFDFH_01118 326425.lhe_0856 0.0 1484.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,3F3VT@33958|Lactobacillaceae 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B CAFIFDFH_01119 326425.lhe_0857 2.46e-224 619.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,3F3TP@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta CAFIFDFH_01120 272621.LBA0841 4.42e-47 151.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,3F7D8@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p CAFIFDFH_01121 1423748.BALB01000001_gene8 1.48e-57 178.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,3F7DV@33958|Lactobacillaceae 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 CAFIFDFH_01122 405566.lhv_0893 0.0 1113.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3U9@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL CAFIFDFH_01123 405566.lhv_0894 1.69e-194 540.0 2CC00@1|root,30489@2|Bacteria,1TW9B@1239|Firmicutes,4I50I@91061|Bacilli,3F52A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - TPR_19 CAFIFDFH_01124 326425.lhe_0862 2.35e-286 782.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,3F3ZP@33958|Lactobacillaceae 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - ko:K02358,ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 CAFIFDFH_01125 326425.lhe_0863 5.6e-279 767.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,3F40B@33958|Lactobacillaceae 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N CAFIFDFH_01126 326425.lhe_0864 1.71e-300 820.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,3F41K@33958|Lactobacillaceae 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX CAFIFDFH_01127 405566.lhv_0898 7.88e-137 387.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,3F44G@33958|Lactobacillaceae 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 CAFIFDFH_01128 1423748.BALB01000001_gene1 9.95e-56 186.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HA0N@91061|Bacilli,3F4J0@33958|Lactobacillaceae 91061|Bacilli E Amino Acid potE - - - - - - - - - - - AA_permease_2 CAFIFDFH_01129 891391.LAC30SC_04260 8.3e-227 633.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HA0N@91061|Bacilli,3F4J0@33958|Lactobacillaceae 91061|Bacilli E Amino Acid potE - - - - - - - - - - - AA_permease_2 CAFIFDFH_01130 405566.lhv_0902 1.26e-245 674.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,3F4F7@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase CAFIFDFH_01131 326425.lhe_0868 0.0 909.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,3F48V@33958|Lactobacillaceae 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 CAFIFDFH_01132 405566.lhv_0905 0.0 867.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,3F3VJ@33958|Lactobacillaceae 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC CAFIFDFH_01133 326425.lhe_0870 4.85e-107 315.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,3F3U0@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep CAFIFDFH_01134 405566.lhv_0907 3.84e-279 763.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,3F419@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CAFIFDFH_01135 405566.lhv_0908 2.68e-224 618.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,3F4UH@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CAFIFDFH_01136 326425.lhe_0873 5.66e-184 511.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,3F3MA@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N CAFIFDFH_01137 326425.lhe_0874 1.76e-277 759.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspC - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CAFIFDFH_01138 405566.lhv_0911 3.67e-254 697.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,3F4S9@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC CAFIFDFH_01139 405566.lhv_0912 9.93e-266 727.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX1 - - - - - - - - - - - Beta-lactamase,SLH CAFIFDFH_01140 326425.lhe_0877 4.28e-136 384.0 COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,4HHQT@91061|Bacilli,3F4BS@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain yjhB - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,Nudix_N CAFIFDFH_01141 326425.lhe_0878 0.0 1036.0 COG2267@1|root,COG2267@2|Bacteria,1UHVZ@1239|Firmicutes,4ISGG@91061|Bacilli,3F5G1@33958|Lactobacillaceae 91061|Bacilli I Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974,DUF308 CAFIFDFH_01142 326425.lhe_1390 1.59e-64 196.0 29P3D@1|root,30A1J@2|Bacteria,1U62Q@1239|Firmicutes,4IFRV@91061|Bacilli,3F6W2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01143 326425.lhe_1391 1.1e-62 192.0 2CE9Z@1|root,33CNB@2|Bacteria,1VNIV@1239|Firmicutes,4HRR9@91061|Bacilli,3F7UX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01144 405566.lhv_1460 1.4e-160 449.0 COG1760@1|root,COG1760@2|Bacteria,1V8XQ@1239|Firmicutes,4HJWN@91061|Bacilli,3FC4T@33958|Lactobacillaceae 91061|Bacilli E Serine dehydratase beta chain - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_beta CAFIFDFH_01145 405566.lhv_1461 3.13e-196 545.0 COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli,3F3X8@33958|Lactobacillaceae 91061|Bacilli E L-serine dehydratase, iron-sulfur-dependent, alpha subunit sdaAA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha CAFIFDFH_01146 405566.lhv_1462 5.32e-73 219.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,3F7D5@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein yitW - - - - - - - - - - - FeS_assembly_P CAFIFDFH_01147 405566.lhv_1463 4.29e-88 258.0 29QAG@1|root,30B9M@2|Bacteria,1U7SC@1239|Firmicutes,4IHPQ@91061|Bacilli,3FA3U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01148 1423734.JCM14202_3406 5.9e-05 44.3 2BHN3@1|root,32BQX@2|Bacteria,1U791@1239|Firmicutes,4IH3V@91061|Bacilli,3F94X@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01149 525365.HMPREF0548_1866 2.36e-61 192.0 29PYK@1|root,30AX1@2|Bacteria,1U77U@1239|Firmicutes,4IH2M@91061|Bacilli,3F933@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01150 1423748.BALB01000003_gene495 1.97e-30 117.0 COG0791@1|root,COG0791@2|Bacteria,1VB5V@1239|Firmicutes,4HN9W@91061|Bacilli,3F3P4@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family - - - - - - - - - - - - NLPC_P60,PG_binding_1,SLAP CAFIFDFH_01151 405566.lhv_1473 1.51e-281 769.0 29V6Q@1|root,30GKE@2|Bacteria,1UG8H@1239|Firmicutes,4IF4J@91061|Bacilli,3F5M6@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP CAFIFDFH_01152 405566.lhv_1475 1.29e-299 817.0 29XAY@1|root,30J0K@2|Bacteria,1UK2K@1239|Firmicutes,4ITGE@91061|Bacilli,3F5Q0@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF3883) - - - - - - - - - - - - DUF3883 CAFIFDFH_01154 395494.Galf_2918 3.13e-66 221.0 COG0732@1|root,COG0732@2|Bacteria,1MXVH@1224|Proteobacteria,2VM15@28216|Betaproteobacteria,44WNN@713636|Nitrosomonadales 28216|Betaproteobacteria L PFAM restriction modification system DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S CAFIFDFH_01155 908339.HMPREF9265_0776 3.04e-59 201.0 COG0732@1|root,COG0732@2|Bacteria,1TT1D@1239|Firmicutes,4HTQA@91061|Bacilli,3F6TD@33958|Lactobacillaceae 91061|Bacilli V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S CAFIFDFH_01156 405566.lhv_1480 0.0 972.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli,3F4HM@33958|Lactobacillaceae 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase CAFIFDFH_01157 405566.lhv_1481 0.0 2107.0 COG4096@1|root,COG4096@2|Bacteria,1UI7V@1239|Firmicutes,4HA94@91061|Bacilli,3F4JF@33958|Lactobacillaceae 91061|Bacilli L DEAD/DEAH box helicase hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF4145,EcoEI_R_C,HSDR_N,Helicase_C,ResIII CAFIFDFH_01158 405566.lhv_1873 3.66e-144 407.0 COG1309@1|root,COG1309@2|Bacteria,1U9UE@1239|Firmicutes,4HM7U@91061|Bacilli,3F403@33958|Lactobacillaceae 91061|Bacilli K WHG domain - - - - - - - - - - - - TetR_N,WHG CAFIFDFH_01159 326425.lhe_0342 1.16e-51 162.0 2A5EV@1|root,30U4Q@2|Bacteria,1U6B2@1239|Firmicutes,4IG2J@91061|Bacilli,3F7HR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01160 405566.lhv_1877 0.0 956.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD4 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 CAFIFDFH_01161 326425.lhe_0340 3.4e-154 433.0 COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli,3F4RP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CAFIFDFH_01162 405566.lhv_1879 1.67e-230 637.0 COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,3F3K5@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease yxeA - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CAFIFDFH_01163 405566.lhv_1880 8.42e-124 352.0 COG1309@1|root,COG1309@2|Bacteria,1V4D3@1239|Firmicutes,4HJ8Z@91061|Bacilli,3F6ZM@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CAFIFDFH_01164 326425.lhe_0337 4.23e-145 408.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F5SD@33958|Lactobacillaceae 91061|Bacilli G phosphoglycerate mutase - - - - - - - - - - - - His_Phos_1 CAFIFDFH_01165 326425.lhe_0336 7.18e-183 508.0 COG1073@1|root,COG1073@2|Bacteria,1V43W@1239|Firmicutes,4HNBU@91061|Bacilli,3F4SI@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase family - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 CAFIFDFH_01166 326425.lhe_0335 1.06e-185 515.0 COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,4HFN2@91061|Bacilli,3F4KR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0246 family XK27_08125 - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD CAFIFDFH_01167 326425.lhe_0334 2.33e-156 438.0 2CBCD@1|root,309KB@2|Bacteria,1U59M@1239|Firmicutes,4IF11@91061|Bacilli,3F5A8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01168 326425.lhe_0333 1.59e-65 201.0 COG1085@1|root,COG1085@2|Bacteria,1TSNU@1239|Firmicutes,4H9TY@91061|Bacilli,3F3JH@33958|Lactobacillaceae 91061|Bacilli C Domain of unknown function (DUF4931) - - - - - - - - - - - - DUF4931 CAFIFDFH_01169 1033837.WANG_0317 9.06e-36 131.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F55P@33958|Lactobacillaceae 91061|Bacilli L transposase, IS605 OrfB family - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon CAFIFDFH_01170 326425.lhe_0332 1.23e-179 503.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,3F4WU@33958|Lactobacillaceae 91061|Bacilli U amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 CAFIFDFH_01171 405566.lhv_1886 0.0 1691.0 COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli,3F3UH@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 CAFIFDFH_01172 326425.lhe_0329 4.12e-79 235.0 COG1388@1|root,COG1388@2|Bacteria,1U5V5@1239|Firmicutes,4IFIT@91061|Bacilli,3F6J1@33958|Lactobacillaceae 91061|Bacilli M LysM domain lysM - - - - - - - - - - - - CAFIFDFH_01173 326425.lhe_0328 8.59e-224 618.0 29NN9@1|root,309K7@2|Bacteria,1U59F@1239|Firmicutes,4IF0Q@91061|Bacilli,3F59C@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01174 1423748.BALB01000035_gene1973 3.23e-289 791.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,3F3T5@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein mdtG2 - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,Sugar_tr CAFIFDFH_01175 326425.lhe_1834 7.09e-135 383.0 COG1476@1|root,COG1476@2|Bacteria,1V36C@1239|Firmicutes,4IT3D@91061|Bacilli,3F65G@33958|Lactobacillaceae 91061|Bacilli K DNA-binding helix-turn-helix protein - - - - - - - - - - - - HTH_3 CAFIFDFH_01176 405566.lhv_0253 1.66e-136 386.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,3F49S@33958|Lactobacillaceae 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran CAFIFDFH_01177 405566.lhv_0252 3.77e-288 789.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,3F3Y7@33958|Lactobacillaceae 91061|Bacilli F xanthine permease pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16169 - - - - ko00000,ko02000 2.A.40,2.A.40.3.1 - iSB619.SA_RS02140 Xan_ur_permease CAFIFDFH_01178 326425.lhe_1837 4.05e-205 566.0 COG2207@1|root,COG2207@2|Bacteria,1V8G6@1239|Firmicutes,4HIF6@91061|Bacilli,3FBER@33958|Lactobacillaceae 91061|Bacilli K AraC-like ligand binding domain msmR - - - - - - - - - - - AraC_binding,HTH_18 CAFIFDFH_01179 405566.lhv_0250 0.0 981.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepDA - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 CAFIFDFH_01180 405566.lhv_0249 2.1e-63 194.0 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli,3F8H8@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 CAFIFDFH_01181 1423748.BALB01000008_gene975 3.64e-41 140.0 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli,3F8H8@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 CAFIFDFH_01182 405566.lhv_0248 2.47e-308 840.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,3F3P8@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase CAFIFDFH_01183 326425.lhe_1841 0.0 1077.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,3F42X@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase CAFIFDFH_01184 326425.lhe_1842 1.25e-114 330.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,3F55D@33958|Lactobacillaceae 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE - - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH CAFIFDFH_01185 326425.lhe_1843 2.02e-88 259.0 29P4Y@1|root,30A35@2|Bacteria,1U64K@1239|Firmicutes,4IFU4@91061|Bacilli,3F712@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1934) - - - - - - - - - - - - DUF1934 CAFIFDFH_01186 326425.lhe_1844 0.0 926.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4IQRC@91061|Bacilli,3FC99@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K06885 - - - - ko00000 - - - HD CAFIFDFH_01187 326425.lhe_1845 5.78e-57 177.0 29PEC@1|root,30ACI@2|Bacteria,1U6GK@1239|Firmicutes,4IG8S@91061|Bacilli,3F7VQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01188 1423748.BALB01000008_gene964 4.7e-87 263.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,4HE30@91061|Bacilli,3F3ZI@33958|Lactobacillaceae 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK CAFIFDFH_01189 748671.LCRIS_00227 2.84e-68 215.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,4HE30@91061|Bacilli,3F3ZI@33958|Lactobacillaceae 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK CAFIFDFH_01190 326425.lhe_1847 1.55e-225 622.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3U2@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N CAFIFDFH_01191 326425.lhe_1848 7.46e-241 668.0 2DKI3@1|root,309IT@2|Bacteria,1U56A@1239|Firmicutes,4IEXK@91061|Bacilli,3F4WY@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - FIVAR,SLAP CAFIFDFH_01192 326425.lhe_1891 0.0 1149.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4JI@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - - - - - - - - - - - E1-E2_ATPase,Hydrolase CAFIFDFH_01193 326425.lhe_1892 2.23e-260 716.0 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HP0X@91061|Bacilli,3FCEG@33958|Lactobacillaceae 91061|Bacilli P Sodium/hydrogen exchanger family napA - - - - - - - - - - - Na_H_Exchanger,Usp CAFIFDFH_01194 1423748.BALB01000014_gene1354 9e-66 200.0 COG2161@1|root,COG2161@2|Bacteria,1U6UC@1239|Firmicutes,4IGN6@91061|Bacilli,3F8I1@33958|Lactobacillaceae 91061|Bacilli D Antitoxin component of a toxin-antitoxin (TA) module - - - ko:K19159 - - - - ko00000,ko02048 - - - PhdYeFM_antitox CAFIFDFH_01195 405566.lhv_2907 1.37e-63 193.0 COG4115@1|root,COG4115@2|Bacteria,1VEN0@1239|Firmicutes,4HRVW@91061|Bacilli,3F80N@33958|Lactobacillaceae 91061|Bacilli S YoeB-like toxin of bacterial type II toxin-antitoxin system yoeB - - ko:K19158 - - - - ko00000,ko01000,ko02048 - - - YoeB_toxin CAFIFDFH_01196 405566.lhv_2067 0.0 972.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HIAU@91061|Bacilli,3F3JJ@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran CAFIFDFH_01197 405566.lhv_2068 3.09e-113 328.0 COG3595@1|root,COG3595@2|Bacteria,1VKFR@1239|Firmicutes,4HKWD@91061|Bacilli,3F701@33958|Lactobacillaceae 91061|Bacilli S Putative adhesin - - - - - - - - - - - - DUF4097 CAFIFDFH_01198 326425.lhe_1896 2.98e-205 568.0 COG1396@1|root,COG1396@2|Bacteria,1U54X@1239|Firmicutes,4IEW2@91061|Bacilli,3F4P7@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins mutR - - - - - - - - - - - HTH_3 CAFIFDFH_01199 326425.lhe_1897 7.47e-63 192.0 2BRU7@1|root,32KUC@2|Bacteria,1U6UW@1239|Firmicutes,4IGNS@91061|Bacilli,3F8IR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01200 326425.lhe_1898 3.04e-154 433.0 COG1266@1|root,COG1266@2|Bacteria,1VFRX@1239|Firmicutes,4HRQQ@91061|Bacilli,3F4Q0@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi CAFIFDFH_01201 405566.lhv_2072 1.79e-248 684.0 COG1434@1|root,COG1434@2|Bacteria,1V8H4@1239|Firmicutes,4HI4B@91061|Bacilli,3FC81@33958|Lactobacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 CAFIFDFH_01202 1423748.BALB01000021_gene1667 4e-16 76.6 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F44P@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD CAFIFDFH_01203 1423748.BALB01000021_gene1667 7.4e-118 359.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F44P@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD CAFIFDFH_01204 1423748.BALB01000021_gene1667 2.3e-80 259.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F44P@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD CAFIFDFH_01205 1423748.BALB01000021_gene1667 4.09e-203 583.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F44P@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD CAFIFDFH_01206 1423748.BALB01000021_gene1667 5.87e-21 91.3 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F44P@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD CAFIFDFH_01207 326425.lhe_1901 2.97e-124 355.0 COG4684@1|root,COG4684@2|Bacteria,1VB4T@1239|Firmicutes,4HMUC@91061|Bacilli,3F497@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt CAFIFDFH_01208 326425.lhe_1902 7.57e-207 571.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HU74@91061|Bacilli,3FB4R@33958|Lactobacillaceae 91061|Bacilli S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red CAFIFDFH_01209 326425.lhe_1903 2.7e-172 480.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,3F3NR@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso CAFIFDFH_01210 326425.lhe_1521 0.0 3036.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,3F3M5@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase S8 family prtB - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - Inhibitor_I9,PA,Peptidase_S8,SLAP,fn3_5 CAFIFDFH_01211 634994.GCWU000323_00921 2.36e-05 46.6 COG4185@1|root,COG4185@2|Bacteria,37BTD@32066|Fusobacteria 32066|Fusobacteria S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - Zeta_toxin CAFIFDFH_01212 405566.lhv_2802 5.04e-100 290.0 COG4185@1|root,COG4185@2|Bacteria,1V1UB@1239|Firmicutes 1239|Firmicutes S Psort location Cytoplasmic, score - - - - - - - - - - - - Zeta_toxin CAFIFDFH_01213 405566.lhv_1636 0.0 876.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,3F49J@33958|Lactobacillaceae 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CAFIFDFH_01214 326425.lhe_1516 2.89e-226 624.0 29NRF@1|root,309PE@2|Bacteria,1U5FS@1239|Firmicutes,4IF75@91061|Bacilli,3F5V8@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP CAFIFDFH_01215 405566.lhv_1633 0.0 993.0 COG0308@1|root,COG0308@2|Bacteria,1U6PC@1239|Firmicutes,4HDA6@91061|Bacilli,3F557@33958|Lactobacillaceae 91061|Bacilli M Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 CAFIFDFH_01216 326425.lhe_1514 5.35e-247 676.0 29NJD@1|root,309H9@2|Bacteria,1U53C@1239|Firmicutes,4IEUN@91061|Bacilli,3F4BP@33958|Lactobacillaceae 91061|Bacilli S Bacteriocin helveticin-J - - - - - - - - - - - - Helveticin_J CAFIFDFH_01217 326425.lhe_1513 3.05e-21 83.2 29PRW@1|root,30AQ3@2|Bacteria,1U6Z1@1239|Firmicutes,4IGTB@91061|Bacilli,3F8R7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01218 405566.lhv_1631 1.87e-68 207.0 COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,4HR7A@91061|Bacilli,3F6PK@33958|Lactobacillaceae 91061|Bacilli L RelB antitoxin - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB CAFIFDFH_01219 326425.lhe_1511 9.65e-193 536.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli,3F4HV@33958|Lactobacillaceae 91061|Bacilli O prohibitin homologues hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 CAFIFDFH_01220 326425.lhe_1510 6.63e-88 261.0 COG0716@1|root,COG0716@2|Bacteria,1V45R@1239|Firmicutes,4HQY8@91061|Bacilli,3F7P2@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin - - - - - - - - - - - - Flavodoxin_4 CAFIFDFH_01221 326425.lhe_1510 1.97e-21 89.0 COG0716@1|root,COG0716@2|Bacteria,1V45R@1239|Firmicutes,4HQY8@91061|Bacilli,3F7P2@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin - - - - - - - - - - - - Flavodoxin_4 CAFIFDFH_01222 326425.lhe_0081 7.23e-93 271.0 COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,4HISW@91061|Bacilli,3F6ZA@33958|Lactobacillaceae 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins def2 - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase CAFIFDFH_01223 326425.lhe_0078 5.59e-250 685.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX1 - - - - - - - - - - - Beta-lactamase,SLH CAFIFDFH_01224 326425.lhe_0077 0.0 1879.0 COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,3F3YQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII CAFIFDFH_01225 1423748.BALB01000018_gene1516 2.46e-32 123.0 COG0531@1|root,COG0531@2|Bacteria,1TRUM@1239|Firmicutes,4HE3V@91061|Bacilli,3F3Y1@33958|Lactobacillaceae 91061|Bacilli E amino acid - - - ko:K20265 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 - - AA_permease_2 CAFIFDFH_01226 1423748.BALB01000018_gene1516 1.13e-115 345.0 COG0531@1|root,COG0531@2|Bacteria,1TRUM@1239|Firmicutes,4HE3V@91061|Bacilli,3F3Y1@33958|Lactobacillaceae 91061|Bacilli E amino acid - - - ko:K20265 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 - - AA_permease_2 CAFIFDFH_01227 326425.lhe_0075 1.25e-204 565.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli,3F4GK@33958|Lactobacillaceae 91061|Bacilli L exodeoxyribonuclease III xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos CAFIFDFH_01228 326425.lhe_0074 5.57e-215 592.0 COG3001@1|root,COG3001@2|Bacteria,1U79A@1239|Firmicutes,4HAZS@91061|Bacilli,3F3RK@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase enzyme family - - - - - - - - - - - - Fructosamin_kin CAFIFDFH_01229 326425.lhe_0073 1.86e-244 671.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HH0S@91061|Bacilli,3FB6C@33958|Lactobacillaceae 91061|Bacilli C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhA - 1.1.1.28 ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 M00651 R00704 RC00044 ko00000,ko00001,ko00002,ko01000,ko01504 - - - 2-Hacid_dh,2-Hacid_dh_C CAFIFDFH_01230 1033837.WANG_1623 4.36e-185 515.0 COG0561@1|root,COG0561@2|Bacteria,1U5C1@1239|Firmicutes,4IF34@91061|Bacilli,3F5HG@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 CAFIFDFH_01231 405566.lhv_0061 0.0 1274.0 COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,4HAS9@91061|Bacilli,3F4B4@33958|Lactobacillaceae 91061|Bacilli J elongation factor G fusA1 - - - - - - - - - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU CAFIFDFH_01232 326425.lhe_0069 2.1e-211 583.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,3F3PW@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase yvgN - - - - - - - - - - - Aldo_ket_red CAFIFDFH_01233 1033837.WANG_1620 1.84e-100 300.0 29DXA@1|root,300V7@2|Bacteria,1U59E@1239|Firmicutes,4IF0P@91061|Bacilli,3F59A@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - - CAFIFDFH_01234 1033837.WANG_1620 1.83e-102 306.0 29DXA@1|root,300V7@2|Bacteria,1U59E@1239|Firmicutes,4IF0P@91061|Bacilli,3F59A@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - - CAFIFDFH_01235 405566.lhv_2023 5.61e-108 311.0 COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HZ6Z@91061|Bacilli,3FC1P@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 CAFIFDFH_01236 326425.lhe_0240 1.27e-119 345.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA CAFIFDFH_01237 326425.lhe_0240 2.08e-38 135.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA CAFIFDFH_01238 326425.lhe_0239 1.44e-141 400.0 2A5BR@1|root,30U1B@2|Bacteria,1UQ43@1239|Firmicutes,4IFET@91061|Bacilli,3F6BQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01239 326425.lhe_0238 1.35e-102 298.0 29NPC@1|root,309M9@2|Bacteria,1U5BC@1239|Firmicutes,4IF2P@91061|Bacilli,3F5FH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01240 326425.lhe_0237 3.02e-225 622.0 COG1434@1|root,COG1434@2|Bacteria,1UR34@1239|Firmicutes,4HDF2@91061|Bacilli,3F4J5@33958|Lactobacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 CAFIFDFH_01241 748671.LCRIS_01927 1.39e-108 328.0 COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli,3F4UR@33958|Lactobacillaceae 91061|Bacilli S ATPases associated with a variety of cellular activities yheS_2 - - ko:K18231,ko:K19349 ko02010,map02010 - - - br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121.1,3.A.1.121.2,3.A.1.121.3 - - ABC_tran,ABC_tran_Xtn CAFIFDFH_01242 326425.lhe_0235 1.18e-113 325.0 2DKKP@1|root,309U8@2|Bacteria,1U5Q4@1239|Firmicutes,4IFEC@91061|Bacilli,3F6AJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01243 326425.lhe_0234 7.09e-76 227.0 29NYM@1|root,309WQ@2|Bacteria,1U5UZ@1239|Firmicutes,4IFIM@91061|Bacilli,3F6IU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01244 405566.lhv_2029 7.13e-313 852.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,3F48P@33958|Lactobacillaceae 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 CAFIFDFH_01245 326425.lhe_0232 9.69e-317 861.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,3F3RQ@33958|Lactobacillaceae 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt CAFIFDFH_01246 405566.lhv_2031 3.17e-234 644.0 COG0516@1|root,COG0516@2|Bacteria,1TNYF@1239|Firmicutes,4HA55@91061|Bacilli,3F45K@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaC - 1.7.1.7 ko:K00364 ko00230,map00230 - R01134 RC00457 ko00000,ko00001,ko01000 - - iSB619.SA_RS06660 IMPDH CAFIFDFH_01249 326425.lhe_0228 9.06e-259 708.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4HAHJ@91061|Bacilli,3FB4D@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) - - 4.2.1.126 ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - DUF871 CAFIFDFH_01250 326425.lhe_0227 4.08e-248 680.0 COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,4HAEC@91061|Bacilli,3F40A@33958|Lactobacillaceae 91061|Bacilli F aspartate--ammonia ligase asnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 - R00483 RC00010 ko00000,ko00001,ko01000 - - - AsnA CAFIFDFH_01251 748671.LCRIS_01937 1.16e-118 347.0 2EHRA@1|root,30AZX@2|Bacteria,1U7BN@1239|Firmicutes,4IH6T@91061|Bacilli,3F9AB@33958|Lactobacillaceae 91061|Bacilli S YcaO cyclodehydratase, ATP-ad Mg2+-binding - - - - - - - - - - - - - CAFIFDFH_01252 1423748.BALB01000005_gene644 3.11e-98 309.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,3F3M5@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase S8 family prtB - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - Inhibitor_I9,PA,Peptidase_S8,SLAP,fn3_5 CAFIFDFH_01253 1423748.BALB01000005_gene644 2.97e-89 281.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,3F3M5@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase S8 family prtB - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - Inhibitor_I9,PA,Peptidase_S8,SLAP,fn3_5 CAFIFDFH_01254 324831.LGAS_0045 1.19e-32 129.0 COG0810@1|root,COG3266@1|root,COG4932@1|root,COG0810@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal CAFIFDFH_01255 324831.LGAS_0045 2.25e-39 153.0 COG0810@1|root,COG3266@1|root,COG4932@1|root,COG0810@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal CAFIFDFH_01256 349123.Lreu23DRAFT_4946 2e-49 180.0 COG0810@1|root,COG3266@1|root,COG4932@1|root,COG0810@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - Gram_pos_anchor,MucBP,YSIRK_signal CAFIFDFH_01257 1423748.BALB01000005_gene651 8.87e-35 135.0 COG3266@1|root,COG3266@2|Bacteria,1VSP5@1239|Firmicutes,4HUK1@91061|Bacilli,3F4FY@33958|Lactobacillaceae 91061|Bacilli M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal CAFIFDFH_01258 405566.lhv_1715 6.7e-77 229.0 COG0526@1|root,COG0526@2|Bacteria,1U6PP@1239|Firmicutes,4IGGN@91061|Bacilli,3F89E@33958|Lactobacillaceae 91061|Bacilli CO Thioredoxin - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin CAFIFDFH_01259 405566.lhv_1714 2.51e-152 428.0 COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1V2NW@1239|Firmicutes,4HGAA@91061|Bacilli,3F6DW@33958|Lactobacillaceae 91061|Bacilli K Rhodanese Homology Domain - - - - - - - - - - - - HTH_20,HTH_5,Rhodanese CAFIFDFH_01260 326425.lhe_1578 3.8e-222 612.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,3F411@33958|Lactobacillaceae 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 CAFIFDFH_01261 1423748.BALB01000005_gene656 2.03e-30 112.0 COG2761@1|root,COG2761@2|Bacteria,1TZ1N@1239|Firmicutes,4HEBF@91061|Bacilli,3F5IF@33958|Lactobacillaceae 91061|Bacilli Q DSBA-like thioredoxin domain frnE - 5.3.4.1 ko:K01829 - - - - ko00000,ko01000 - - - DSBA CAFIFDFH_01262 1423748.BALB01000005_gene656 4.14e-60 190.0 COG2761@1|root,COG2761@2|Bacteria,1TZ1N@1239|Firmicutes,4HEBF@91061|Bacilli,3F5IF@33958|Lactobacillaceae 91061|Bacilli Q DSBA-like thioredoxin domain frnE - 5.3.4.1 ko:K01829 - - - - ko00000,ko01000 - - - DSBA CAFIFDFH_01263 1033837.WANG_1181 5.82e-36 130.0 COG5464@1|root,COG5464@2|Bacteria,1V1A7@1239|Firmicutes,4HG0B@91061|Bacilli,3F655@33958|Lactobacillaceae 91061|Bacilli S PD-(D/E)XK nuclease family transposase - - - - - - - - - - - - PDDEXK_2 CAFIFDFH_01264 1423748.BALB01000005_gene660 1.26e-215 601.0 COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,4HB6I@91061|Bacilli,3F5QB@33958|Lactobacillaceae 91061|Bacilli I Belongs to the phosphatidylserine decarboxylase family psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase CAFIFDFH_01265 405566.lhv_1708 7.82e-50 158.0 COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,4HB6I@91061|Bacilli,3F5QB@33958|Lactobacillaceae 91061|Bacilli I Belongs to the phosphatidylserine decarboxylase family psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase CAFIFDFH_01266 326425.lhe_1574 7.41e-65 197.0 COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,4HRGW@91061|Bacilli,3F87Y@33958|Lactobacillaceae 91061|Bacilli KT PspC domain pspC - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC CAFIFDFH_01268 326425.lhe_1572 6.06e-309 842.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,3F43S@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 CAFIFDFH_01269 405566.lhv_1705 1.83e-196 545.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,3F480@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N CAFIFDFH_01270 326425.lhe_1570 9.06e-159 445.0 COG1376@1|root,COG1376@2|Bacteria,1V4KP@1239|Firmicutes,4HIBF@91061|Bacilli,3F6PH@33958|Lactobacillaceae 91061|Bacilli M ErfK YbiS YcfS YnhG - - - - - - - - - - - - Rib,YkuD CAFIFDFH_01271 405566.lhv_0791 0.0 936.0 COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4IS6U@91061|Bacilli,3FBSR@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA CAFIFDFH_01272 405566.lhv_0790 4.46e-167 467.0 COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,3FC92@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C CAFIFDFH_01273 326425.lhe_0750 1.3e-78 234.0 COG5658@1|root,2ZY3R@2|Bacteria,1VKM4@1239|Firmicutes,4I0CM@91061|Bacilli,3F6IB@33958|Lactobacillaceae 91061|Bacilli S SdpI/YhfL protein family - - - - - - - - - - - - SdpI CAFIFDFH_01274 326425.lhe_0749 1.08e-219 607.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,3F40I@33958|Lactobacillaceae 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI CAFIFDFH_01275 405566.lhv_0788 2.84e-286 781.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CAFIFDFH_01276 748671.LCRIS_00747 5.04e-48 159.0 COG5434@1|root,COG5434@2|Bacteria,1TQXN@1239|Firmicutes,4HBHT@91061|Bacilli,3F4Y5@33958|Lactobacillaceae 91061|Bacilli M Protein of unknown function (DUF3737) - - - - - - - - - - - - DUF3737 CAFIFDFH_01277 1545701.LACWKB10_0536 1.32e-50 169.0 COG5434@1|root,COG5434@2|Bacteria,1TQXN@1239|Firmicutes,4HBHT@91061|Bacilli,3F4Y5@33958|Lactobacillaceae 91061|Bacilli M Protein of unknown function (DUF3737) - - - - - - - - - - - - DUF3737 CAFIFDFH_01279 326425.lhe_0745 3.88e-284 776.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase CAFIFDFH_01280 326425.lhe_0744 2.53e-240 660.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli,3F4CI@33958|Lactobacillaceae 91061|Bacilli L N-6 DNA Methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase CAFIFDFH_01281 326425.lhe_0743 8.83e-108 311.0 COG4940@1|root,COG4940@2|Bacteria,1U6NI@1239|Firmicutes,4IGFH@91061|Bacilli,3F87B@33958|Lactobacillaceae 91061|Bacilli U Putative Competence protein ComGF - - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF CAFIFDFH_01282 326425.lhe_0742 1.18e-55 173.0 2BS3U@1|root,32M4K@2|Bacteria,1U6G6@1239|Firmicutes,4IG89@91061|Bacilli,3F7UI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01283 326425.lhe_0741 2.04e-95 278.0 29ZCH@1|root,30MB3@2|Bacteria,1U645@1239|Firmicutes,4IFTR@91061|Bacilli,3F6ZT@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K02246 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl CAFIFDFH_01284 326425.lhe_0740 6.15e-66 201.0 COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli,3F7ZC@33958|Lactobacillaceae 91061|Bacilli U competence protein ComGC comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl CAFIFDFH_01285 326425.lhe_0739 5.57e-224 619.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,3F3S9@33958|Lactobacillaceae 91061|Bacilli NU type II secretion system comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF CAFIFDFH_01286 326425.lhe_0738 8.35e-230 633.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,3F4HY@33958|Lactobacillaceae 91061|Bacilli NU Type II IV secretion system protein comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE CAFIFDFH_01287 326425.lhe_0737 1.09e-168 471.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,3F4WF@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg CAFIFDFH_01288 326425.lhe_0736 5.73e-120 342.0 COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,4HMDE@91061|Bacilli,3F57S@33958|Lactobacillaceae 91061|Bacilli S VanZ like family - - - - - - - - - - - - VanZ CAFIFDFH_01289 326425.lhe_1734 5.04e-71 213.0 2BRXH@1|root,32KXS@2|Bacteria,1U6EY@1239|Firmicutes,4IG6S@91061|Bacilli,3F7RT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01290 326425.lhe_1733 7.71e-133 376.0 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli,3F65D@33958|Lactobacillaceae 91061|Bacilli F dUTP diphosphatase dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase CAFIFDFH_01291 326425.lhe_1732 0.0 886.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,3F3W8@33958|Lactobacillaceae 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI CAFIFDFH_01292 405566.lhv_0369 0.0 1004.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,3F3PR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c CAFIFDFH_01293 405566.lhv_0370 0.0 957.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,3F4K7@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g CAFIFDFH_01294 326425.lhe_1729 2.1e-99 288.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,3F6HS@33958|Lactobacillaceae 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 CAFIFDFH_01295 405566.lhv_0372 1.76e-178 497.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,3F3TD@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind CAFIFDFH_01296 326425.lhe_1727 8.62e-120 343.0 COG1595@1|root,COG1595@2|Bacteria,1VG7U@1239|Firmicutes,4HNKD@91061|Bacilli,3F8D5@33958|Lactobacillaceae 91061|Bacilli K Belongs to the sigma-70 factor family comX - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CAFIFDFH_01297 272621.LBA0352 2.41e-45 146.0 29PH8@1|root,30AFD@2|Bacteria,1U6KC@1239|Firmicutes,4IGD6@91061|Bacilli,3F83D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01298 405566.lhv_0375 0.0 969.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,3F4R2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N CAFIFDFH_01299 1423748.BALB01000002_gene270 5.66e-109 329.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,3F4RN@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C CAFIFDFH_01300 1423748.BALB01000002_gene270 1.2e-282 780.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,3F4RN@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C CAFIFDFH_01301 326425.lhe_1723 8.53e-34 115.0 COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4HR1W@91061|Bacilli,3F86Y@33958|Lactobacillaceae 91061|Bacilli U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE CAFIFDFH_01302 326425.lhe_1722 5.2e-132 374.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,3F55W@33958|Lactobacillaceae 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG CAFIFDFH_01303 326425.lhe_1721 7.71e-90 264.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,3F64I@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N CAFIFDFH_01304 326425.lhe_1720 3.02e-160 449.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,3F3VQ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 CAFIFDFH_01305 405566.lhv_0685 5.25e-37 124.0 29PIA@1|root,30AGF@2|Bacteria,1U6MM@1239|Firmicutes,4IGEE@91061|Bacilli,3F85J@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01306 326425.lhe_0656 1.83e-54 170.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,3F6XQ@33958|Lactobacillaceae 91061|Bacilli G phosphocarrier protein HPR ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr CAFIFDFH_01307 326425.lhe_0657 0.0 1083.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,3F3MS@33958|Lactobacillaceae 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C CAFIFDFH_01308 326425.lhe_0658 1.54e-87 257.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F6HJ@33958|Lactobacillaceae 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC CAFIFDFH_01309 326425.lhe_0659 5.25e-178 495.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HID6@91061|Bacilli,3F5G4@33958|Lactobacillaceae 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K16511 - - - - ko00000 - - - MecA CAFIFDFH_01310 405566.lhv_0690 6.26e-158 445.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,3F4BZ@33958|Lactobacillaceae 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA CAFIFDFH_01311 405566.lhv_0691 2.25e-145 409.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,3F6QR@33958|Lactobacillaceae 91061|Bacilli Q Thioredoxin yjbH - - - - - - - - - - - Thioredoxin_5 CAFIFDFH_01312 326425.lhe_0662 7.26e-146 410.0 COG4116@1|root,COG4116@2|Bacteria,1TTVM@1239|Firmicutes,4I4A3@91061|Bacilli,3F4YS@33958|Lactobacillaceae 91061|Bacilli S CYTH - - - - - - - - - - - - CYTH CAFIFDFH_01313 326425.lhe_0663 4.88e-147 414.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,3F452@33958|Lactobacillaceae 91061|Bacilli S RelA SpoT domain protein yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT CAFIFDFH_01314 405566.lhv_0694 2.07e-196 544.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,3F45D@33958|Lactobacillaceae 91061|Bacilli F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase CAFIFDFH_01315 326425.lhe_0665 4.97e-218 601.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3F46Z@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD2 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 CAFIFDFH_01316 326425.lhe_0666 8.64e-40 145.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,4HAYH@91061|Bacilli,3F3QX@33958|Lactobacillaceae 91061|Bacilli S Myosin-crossreactive antigen mycA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046983,GO:0048037,GO:0050151,GO:0050660,GO:0050662,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA CAFIFDFH_01317 1423748.BALB01000004_gene622 1.01e-267 741.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,4HAYH@91061|Bacilli,3F3QX@33958|Lactobacillaceae 91061|Bacilli S Myosin-crossreactive antigen mycA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046983,GO:0048037,GO:0050151,GO:0050660,GO:0050662,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA CAFIFDFH_01318 326425.lhe_0666 5.81e-70 226.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,4HAYH@91061|Bacilli,3F3QX@33958|Lactobacillaceae 91061|Bacilli S Myosin-crossreactive antigen mycA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046983,GO:0048037,GO:0050151,GO:0050660,GO:0050662,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA CAFIFDFH_01319 405566.lhv_0699 1.48e-151 427.0 COG0398@1|root,COG0398@2|Bacteria,1V6V7@1239|Firmicutes,4HITM@91061|Bacilli,3F417@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc CAFIFDFH_01320 405566.lhv_0700 1.5e-257 704.0 COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,3F3RC@33958|Lactobacillaceae 91061|Bacilli G Lactonase, 7-bladed beta-propeller pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase CAFIFDFH_01321 326425.lhe_0669 0.0 1749.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HTQ4@91061|Bacilli,3FC0Z@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus pacL - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 CAFIFDFH_01322 1423748.BALB01000004_gene626 4.91e-37 126.0 COG3731@1|root,COG3731@2|Bacteria,1VGKB@1239|Firmicutes,4HNJN@91061|Bacilli,3F8EZ@33958|Lactobacillaceae 91061|Bacilli G PTS system glucitol/sorbitol-specific IIA component srlB - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA CAFIFDFH_01323 1423748.BALB01000004_gene626 1.12e-30 110.0 COG3731@1|root,COG3731@2|Bacteria,1VGKB@1239|Firmicutes,4HNJN@91061|Bacilli,3F8EZ@33958|Lactobacillaceae 91061|Bacilli G PTS system glucitol/sorbitol-specific IIA component srlB - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA CAFIFDFH_01324 326425.lhe_0671 8.55e-270 740.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3F418@33958|Lactobacillaceae 91061|Bacilli S AI-2E family transporter XK27_05220 - - - - - - - - - - - AI-2E_transport CAFIFDFH_01325 1423748.BALB01000004_gene628 1.23e-135 383.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,3F42Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase CAFIFDFH_01326 326425.lhe_0673 4.46e-90 263.0 COG4835@1|root,COG4835@2|Bacteria,1VHA6@1239|Firmicutes,4HPTC@91061|Bacilli,3FCDF@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1149) WQ51_03320 - - - - - - - - - - - DUF1149 CAFIFDFH_01327 326425.lhe_0674 0.0 1455.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,3F3JZ@33958|Lactobacillaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma CAFIFDFH_01328 326425.lhe_0675 8.89e-290 791.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,3F3SA@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 inactive domain protein ymfF - - - - - - - - - - - Peptidase_M16_C CAFIFDFH_01329 405566.lhv_0709 2.62e-301 822.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,3F4MU@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C CAFIFDFH_01330 326425.lhe_0677 3.27e-170 475.0 COG1028@1|root,COG1028@2|Bacteria,1V0YW@1239|Firmicutes,4ISGK@91061|Bacilli,3FBEA@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 CAFIFDFH_01331 326425.lhe_0678 1.3e-189 535.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,3F3SM@33958|Lactobacillaceae 91061|Bacilli S Helix-turn-helix domain ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 CAFIFDFH_01332 326425.lhe_0679 1.22e-126 360.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,3F4BI@33958|Lactobacillaceae 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf CAFIFDFH_01333 326425.lhe_0680 2.66e-249 686.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA CAFIFDFH_01334 326425.lhe_0681 1.01e-291 808.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,3F3WX@33958|Lactobacillaceae 91061|Bacilli S Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 CAFIFDFH_01335 405566.lhv_0715 2.26e-267 733.0 COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli,3F4JV@33958|Lactobacillaceae 91061|Bacilli M transferase tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 CAFIFDFH_01336 326425.lhe_0683 2.4e-152 428.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli,3F3SQ@33958|Lactobacillaceae 91061|Bacilli S YigZ family yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 CAFIFDFH_01337 326425.lhe_0684 4.28e-312 850.0 COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli,3F3TQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K02240 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1 - - DEAD,Helicase_C,ResIII CAFIFDFH_01338 326425.lhe_0685 7.21e-173 481.0 COG1040@1|root,COG1040@2|Bacteria,1V73S@1239|Firmicutes,4HJ6R@91061|Bacilli,3F714@33958|Lactobacillaceae 91061|Bacilli S Competence protein comFC - - ko:K02242 - M00429 - - ko00000,ko00002,ko02044 - - - Pribosyltran CAFIFDFH_01339 326425.lhe_0686 5.41e-123 351.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,3F40M@33958|Lactobacillaceae 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE CAFIFDFH_01340 405566.lhv_0720 0.0 1562.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,3F4DH@33958|Lactobacillaceae 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SecA_DEAD,SecA_PP_bind,SecA_SW CAFIFDFH_01341 326425.lhe_0688 3.57e-237 652.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,3F3SN@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 CAFIFDFH_01342 405566.lhv_0722 1.19e-43 143.0 29P93@1|root,30A77@2|Bacteria,1U6A5@1239|Firmicutes,4IG1D@91061|Bacilli,3F7F0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01343 326425.lhe_0690 3.54e-230 634.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,3F3Z3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N CAFIFDFH_01344 1423748.BALB01000001_gene178 1.35e-201 558.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,3F42N@33958|Lactobacillaceae 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT CAFIFDFH_01345 326425.lhe_0692 3.46e-241 663.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,3F4C8@33958|Lactobacillaceae 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N CAFIFDFH_01346 405566.lhv_0727 7.7e-80 238.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,3F4IA@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase CAFIFDFH_01347 405566.lhv_0728 0.0 1143.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,3F457@33958|Lactobacillaceae 91061|Bacilli G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV CAFIFDFH_01348 326425.lhe_0695 0.0 1325.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,3F3XM@33958|Lactobacillaceae 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB CAFIFDFH_01349 326425.lhe_0696 0.0 1875.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,3F4TZ@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran CAFIFDFH_01350 405566.lhv_0731 4.38e-108 313.0 COG3247@1|root,COG3247@2|Bacteria,1V759@1239|Firmicutes,4HK5F@91061|Bacilli,3F58J@33958|Lactobacillaceae 91061|Bacilli S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 CAFIFDFH_01351 405566.lhv_0732 2.97e-211 583.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,3F4NY@33958|Lactobacillaceae 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 CAFIFDFH_01352 326425.lhe_0699 4.42e-248 681.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,3F4D5@33958|Lactobacillaceae 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 CAFIFDFH_01353 326425.lhe_0700 8.23e-219 604.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,3F4AB@33958|Lactobacillaceae 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N CAFIFDFH_01354 326425.lhe_0701 1.16e-128 366.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,3F3M0@33958|Lactobacillaceae 91061|Bacilli O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease CAFIFDFH_01355 326425.lhe_0702 0.0 1092.0 2FIUN@1|root,34AK2@2|Bacteria,1W1FZ@1239|Firmicutes,4HYXZ@91061|Bacilli,3F4QV@33958|Lactobacillaceae 91061|Bacilli S SH3-like domain - - - - - - - - - - - - Big_3,SH3_8 CAFIFDFH_01356 326425.lhe_0534 4.14e-81 241.0 COG0615@1|root,COG0615@2|Bacteria,1V3KY@1239|Firmicutes,4HGWZ@91061|Bacilli,3F65R@33958|Lactobacillaceae 91061|Bacilli IM Glycerol-3-phosphate cytidylyltransferase tagD - 2.7.7.39 ko:K00980 ko00564,map00564 - R00856 RC00002 ko00000,ko00001,ko01000 - - - CTP_transf_like CAFIFDFH_01357 326425.lhe_0533 4.41e-158 444.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4IPQD@91061|Bacilli,3FC8N@33958|Lactobacillaceae 91061|Bacilli K UTRA gntR1 - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA CAFIFDFH_01358 326425.lhe_0532 1.43e-272 745.0 29NKT@1|root,309IS@2|Bacteria,1U569@1239|Firmicutes,4IEXJ@91061|Bacilli,3F4WR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01361 405566.lhv_0532 8.6e-121 345.0 28WK8@1|root,2ZIK8@2|Bacteria,1W6IZ@1239|Firmicutes,4I01D@91061|Bacilli,3F68J@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01362 326425.lhe_0529 2.27e-131 375.0 2DKHC@1|root,309G6@2|Bacteria,1U50G@1239|Firmicutes,4IESF@91061|Bacilli,3F3S2@33958|Lactobacillaceae 91061|Bacilli S SLAP domain slpX - - - - - - - - - - - SLAP CAFIFDFH_01363 891391.LAC30SC_02640 6.7e-19 85.5 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC4N@91061|Bacilli,3FCB3@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase system, EIIC pfoSR - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 CAFIFDFH_01364 272621.LBA0510 1.52e-96 291.0 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC4N@91061|Bacilli,3FCB3@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase system, EIIC pfoSR - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 CAFIFDFH_01365 891391.LAC30SC_02640 4.12e-24 99.4 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC4N@91061|Bacilli,3FCB3@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase system, EIIC pfoSR - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 CAFIFDFH_01366 1423748.BALB01000016_gene1433 2.13e-147 430.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase CAFIFDFH_01367 97137.C821_01847 1.75e-30 117.0 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HM8Q@91061|Bacilli 91061|Bacilli K Transcriptional regulator ansR - - - - - - - - - - - HTH_3 CAFIFDFH_01368 1545701.LACWKB10_1765 6.14e-21 84.3 29PW2@1|root,30AUC@2|Bacteria,1U748@1239|Firmicutes,4IGYU@91061|Bacilli,3F8Y9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_3 CAFIFDFH_01370 272621.LBA0760 9.99e-59 185.0 2BF94@1|root,3291Z@2|Bacteria,1U8BZ@1239|Firmicutes,4II9Y@91061|Bacilli,3FATG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01372 1423748.BALB01000016_gene1437 2.45e-44 146.0 2DKPJ@1|root,30A83@2|Bacteria,1U6BB@1239|Firmicutes,4IG2Y@91061|Bacilli,3F7I8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01373 97137.C821_01854 2.18e-61 208.0 COG2946@1|root,COG2946@2|Bacteria,1VMP1@1239|Firmicutes,4HSQH@91061|Bacilli,3F7FS@33958|Lactobacillaceae 91061|Bacilli L Replication initiation factor - - - - - - - - - - - - Rep_trans CAFIFDFH_01376 797515.HMPREF9103_02281 2.47e-24 103.0 COG4886@1|root,COG4886@2|Bacteria,1UYD7@1239|Firmicutes,4HHUD@91061|Bacilli,3F5NI@33958|Lactobacillaceae 91061|Bacilli NU Mycoplasma protein of unknown function, DUF285 - - - - - - - - - - - - Big_3,DUF285,LRR_5,MucBP,SLAP,WxL CAFIFDFH_01377 405566.lhv_1948 1.84e-159 449.0 2EGNI@1|root,33AEP@2|Bacteria,1U6HF@1239|Firmicutes,4IG9S@91061|Bacilli,3F7XJ@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4430) - - - - - - - - - - - - DUF4430 CAFIFDFH_01378 405566.lhv_1951 5.25e-236 650.0 COG5066@1|root,COG5066@2|Bacteria,1W217@1239|Firmicutes,4I1VH@91061|Bacilli,3F596@33958|Lactobacillaceae 91061|Bacilli U FFAT motif binding - - - - - - - - - - - - - CAFIFDFH_01379 1033837.WANG_1500 0.0 1008.0 2EGNI@1|root,33AEP@2|Bacteria,1VQKC@1239|Firmicutes,4HP40@91061|Bacilli,3F4VE@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4430) - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - DUF1542,DUF4430 CAFIFDFH_01380 405566.lhv_1953 0.0 907.0 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 CAFIFDFH_01382 405566.lhv_1954 5.88e-201 558.0 COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,4HDM2@91061|Bacilli,3F5CF@33958|Lactobacillaceae 91061|Bacilli P ABC-type cobalt transport system permease component CbiQ and related transporters - - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ CAFIFDFH_01383 405566.lhv_1955 0.0 1072.0 COG3845@1|root,COG3845@2|Bacteria,1UI2B@1239|Firmicutes,4ISBR@91061|Bacilli,3FBVX@33958|Lactobacillaceae 91061|Bacilli S AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,CbiQ CAFIFDFH_01384 405566.lhv_1956 1.01e-161 453.0 COG4720@1|root,COG4720@2|Bacteria,1V2DR@1239|Firmicutes,4HFXY@91061|Bacilli,3F4W4@33958|Lactobacillaceae 91061|Bacilli S ECF-type riboflavin transporter, S component - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF-ribofla_trS,ECF_trnsprt CAFIFDFH_01385 1033837.WANG_1510 2.34e-165 469.0 COG5066@1|root,COG5066@2|Bacteria,1W217@1239|Firmicutes,4ITF7@91061|Bacilli,3F5DS@33958|Lactobacillaceae 91061|Bacilli U FFAT motif binding - - - - - - - - - - - - - CAFIFDFH_01386 1033837.WANG_1509 1.55e-70 214.0 COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,4HJN3@91061|Bacilli,3F7NM@33958|Lactobacillaceae 91061|Bacilli E Ethanolamine utilisation - propanediol utilisation eutP - - ko:K04029 - - - - ko00000 - - - PduV-EutP CAFIFDFH_01387 1423748.BALB01000015_gene1399 1.08e-57 185.0 2DKHZ@1|root,309I2@2|Bacteria,1U54Y@1239|Firmicutes,4IEW4@91061|Bacilli,3F4PH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01388 1423748.BALB01000015_gene1399 5.29e-51 169.0 2DKHZ@1|root,309I2@2|Bacteria,1U54Y@1239|Firmicutes,4IEW4@91061|Bacilli,3F4PH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01389 405566.lhv_1777 5.75e-242 664.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4HD98@91061|Bacilli,3FCC6@33958|Lactobacillaceae 91061|Bacilli EJ L-asparaginase, type I ansA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase CAFIFDFH_01390 405566.lhv_2920 7.24e-22 85.1 29PT6@1|root,30ARD@2|Bacteria,1U70J@1239|Firmicutes,4IGUW@91061|Bacilli,3F8TF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01391 326425.lhe_0445 6.41e-163 455.0 29NN1@1|root,309JZ@2|Bacteria,1U591@1239|Firmicutes,4IF0C@91061|Bacilli,3F57G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF4145 CAFIFDFH_01392 326425.lhe_0446 1.08e-307 838.0 COG4640@1|root,COG4640@2|Bacteria,1V6D3@1239|Firmicutes,4IPQE@91061|Bacilli,3F4ZG@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic - - - - - - - - - - - - zf-ribbon_3 CAFIFDFH_01393 405566.lhv_1774 1.23e-173 484.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3F3MG@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein cysA - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CAFIFDFH_01394 405566.lhv_1773 2.28e-250 699.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4HAZG@91061|Bacilli,3F45H@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX CAFIFDFH_01395 405566.lhv_1773 7.72e-129 382.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4HAZG@91061|Bacilli,3F45H@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX CAFIFDFH_01396 405566.lhv_1772 4.36e-162 452.0 COG0406@1|root,COG0406@2|Bacteria,1TQWQ@1239|Firmicutes,4HF2N@91061|Bacilli,3F524@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpm2 - - - - - - - - - - - His_Phos_1 CAFIFDFH_01397 326425.lhe_0448 1.1e-161 452.0 COG5549@1|root,COG5549@2|Bacteria,1VW9X@1239|Firmicutes,4HWF8@91061|Bacilli,3F60X@33958|Lactobacillaceae 91061|Bacilli O PFAM peptidase M10A and M12B, matrixin and adamalysin XK27_08875 - - - - - - - - - - - Peptidase_M10 CAFIFDFH_01398 405566.lhv_1770 0.0 1503.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,3F486@33958|Lactobacillaceae 91061|Bacilli L DNA helicase helD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 CAFIFDFH_01399 405566.lhv_0453 1.98e-196 545.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,3F49U@33958|Lactobacillaceae 91061|Bacilli M mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel CAFIFDFH_01400 1423748.BALB01000002_gene199 3.11e-28 108.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,3F6KB@33958|Lactobacillaceae 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 CAFIFDFH_01401 326425.lhe_1651 1.63e-62 193.0 29P3Z@1|root,30A26@2|Bacteria,1U63A@1239|Firmicutes,4IFSN@91061|Bacilli,3F6XS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01402 326425.lhe_1650 2.89e-275 751.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,3F3X5@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 CAFIFDFH_01403 326425.lhe_1649 4.13e-230 634.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,3F4AA@33958|Lactobacillaceae 91061|Bacilli K catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 CAFIFDFH_01404 405566.lhv_0458 0.0 922.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,3F4E3@33958|Lactobacillaceae 91061|Bacilli C glycerophosphoryl diester phosphodiesterase - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD CAFIFDFH_01405 405566.lhv_0459 2.42e-74 222.0 2C26E@1|root,3424N@2|Bacteria,1VX4A@1239|Firmicutes,4HXT9@91061|Bacilli,3F70Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01406 326425.lhe_1646 0.0 947.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli,3FC1D@33958|Lactobacillaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family sasH - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,Metallophos,SLH CAFIFDFH_01407 405566.lhv_0461 5.15e-127 363.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli,3F66P@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1027) yutD - - - - - - - - - - - DUF1027 CAFIFDFH_01408 326425.lhe_1644 1.24e-187 521.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,3F49D@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like CAFIFDFH_01409 326425.lhe_1643 7.12e-111 322.0 COG4478@1|root,COG4478@2|Bacteria,1V7UW@1239|Firmicutes,4HHH4@91061|Bacilli,3F4YP@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1461) - - - - - - - - - - - - DUF1461 CAFIFDFH_01410 326425.lhe_1642 5.67e-149 419.0 COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,4HG3F@91061|Bacilli,3F4KG@33958|Lactobacillaceae 91061|Bacilli S SNARE-like domain protein dedA - - ko:K03975 - - - - ko00000 - - - SNARE_assoc CAFIFDFH_01411 326425.lhe_1641 3.89e-195 541.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,3F3NQ@33958|Lactobacillaceae 91061|Bacilli C Ferredoxin--NADP reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 CAFIFDFH_01412 405566.lhv_1808 1.06e-281 772.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,3F4B2@33958|Lactobacillaceae 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 CAFIFDFH_01413 326425.lhe_0403 4.51e-239 659.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr CAFIFDFH_01414 405566.lhv_1806 2.95e-188 525.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,3F4M5@33958|Lactobacillaceae 91061|Bacilli M biosynthesis protein epsB - - - - - - - - - - - GNVR,Wzz CAFIFDFH_01415 326425.lhe_0405 3.79e-159 449.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,3F4BM@33958|Lactobacillaceae 91061|Bacilli D Capsular exopolysaccharide family ywqD - - - - - - - - - - - AAA_31,ParA CAFIFDFH_01416 326425.lhe_0406 1.34e-185 515.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,3F3RT@33958|Lactobacillaceae 91061|Bacilli GM PHP domain protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - CAFIFDFH_01417 585524.HMPREF0493_1458 1.12e-124 358.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HCBG@91061|Bacilli,3F51J@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase rfbP - - ko:K13012,ko:K19428 - - - - ko00000,ko01000,ko01005 - - - Bac_transf CAFIFDFH_01418 1536774.H70357_32340 5.09e-55 188.0 COG1216@1|root,COG1216@2|Bacteria,1V3IY@1239|Firmicutes,4ISXW@91061|Bacilli 91061|Bacilli S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 CAFIFDFH_01419 748671.LCRIS_01757 1.12e-24 100.0 COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,4HEJ1@91061|Bacilli,3F7X4@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 galnac-T15 - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2 CAFIFDFH_01420 747365.Thena_0394 8.65e-72 231.0 COG0463@1|root,COG0463@2|Bacteria,1V2EP@1239|Firmicutes,24GAY@186801|Clostridia 186801|Clostridia M group 2 family protein - - - - - - - - - - - - Glycos_transf_2 CAFIFDFH_01421 1449338.JQLU01000005_gene2993 3.81e-20 98.2 2BIRY@1|root,32CZI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CAFIFDFH_01422 585394.RHOM_12275 1.16e-15 76.6 COG2244@1|root,COG2244@2|Bacteria,1TRRI@1239|Firmicutes,24EFD@186801|Clostridia 186801|Clostridia S membrane protein involved in the export of O-antigen and teichoic acid - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C CAFIFDFH_01423 97139.C824_05430 1.08e-40 150.0 COG2244@1|root,COG2244@2|Bacteria,1TRRI@1239|Firmicutes,24EFD@186801|Clostridia,36VW7@31979|Clostridiaceae 186801|Clostridia S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C CAFIFDFH_01424 1423748.BALB01000004_gene561 2.79e-97 286.0 COG2188@1|root,COG2188@2|Bacteria,1TTCD@1239|Firmicutes,4HEXQ@91061|Bacilli,3F4DA@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein gntR - - - - - - - - - - - GntR,UTRA CAFIFDFH_01425 1423748.BALB01000004_gene561 9.58e-28 105.0 COG2188@1|root,COG2188@2|Bacteria,1TTCD@1239|Firmicutes,4HEXQ@91061|Bacilli,3F4DA@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein gntR - - - - - - - - - - - GntR,UTRA CAFIFDFH_01426 326425.lhe_0599 6.08e-224 617.0 COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,4HB17@91061|Bacilli,3F4T0@33958|Lactobacillaceae 91061|Bacilli F Nucleoside rihC - 3.2.2.1 ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro CAFIFDFH_01427 326425.lhe_0600 0.0 1285.0 COG3158@1|root,COG3158@2|Bacteria,1TRUQ@1239|Firmicutes,4HA8Z@91061|Bacilli,3F4CU@33958|Lactobacillaceae 91061|Bacilli P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans CAFIFDFH_01428 326425.lhe_0601 2.22e-162 454.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,3F43N@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A CAFIFDFH_01429 326425.lhe_0602 4.22e-215 594.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HA87@91061|Bacilli,3F3S5@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB,Rib_5-P_isom_A CAFIFDFH_01430 405566.lhv_0609 5.05e-204 563.0 COG1085@1|root,COG1085@2|Bacteria,1TSNU@1239|Firmicutes,4H9TY@91061|Bacilli,3F3JH@33958|Lactobacillaceae 91061|Bacilli C Domain of unknown function (DUF4931) - - - - - - - - - - - - DUF4931 CAFIFDFH_01431 405566.lhv_0443 0.0 888.0 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli,3F54U@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 CAFIFDFH_01432 1071400.LBUCD034_0849 4.82e-55 172.0 COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,4HNJ4@91061|Bacilli,3F811@33958|Lactobacillaceae 91061|Bacilli T Belongs to the UPF0237 family XK27_08630 - - ko:K07166 - - - - ko00000 - - - ACT_6 CAFIFDFH_01433 326425.lhe_0605 1.7e-314 857.0 COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,4HBTU@91061|Bacilli,3F4H2@33958|Lactobacillaceae 91061|Bacilli S UPF0210 protein XK27_08635 - - ko:K09157 - - - - ko00000 - - - DUF711 CAFIFDFH_01434 405566.lhv_0605 2.12e-310 846.0 COG1653@1|root,COG1653@2|Bacteria,1UNFN@1239|Firmicutes,4HCSA@91061|Bacilli,3FBF0@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein srrA1 - - ko:K02027,ko:K17244 ko02010,map02010 M00207,M00601 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.40 - - SBP_bac_1,SBP_bac_8 CAFIFDFH_01435 326425.lhe_0389 1.11e-158 446.0 COG4990@1|root,COG4990@2|Bacteria,1V3XE@1239|Firmicutes,4HJBT@91061|Bacilli,3F4HZ@33958|Lactobacillaceae 91061|Bacilli S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 CAFIFDFH_01436 326425.lhe_0388 3.65e-109 314.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,3F63I@33958|Lactobacillaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 CAFIFDFH_01437 326425.lhe_0387 2.79e-178 497.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,3F4XE@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE CAFIFDFH_01438 326425.lhe_0386 0.0 1004.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,3FC7X@33958|Lactobacillaceae 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn CAFIFDFH_01439 891391.LAC30SC_09505 9.54e-74 222.0 29NYN@1|root,309WR@2|Bacteria,1U5V0@1239|Firmicutes,4IFIN@91061|Bacilli,3F6IV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01440 326425.lhe_0384 1.07e-111 322.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,3F6YW@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain rimL - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 CAFIFDFH_01441 1423748.BALB01000012_gene1196 2.43e-65 204.0 COG1811@1|root,COG1811@2|Bacteria,1U5PM@1239|Firmicutes,4HEHT@91061|Bacilli,3F56J@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF554) - - - ko:K07150 - - - - ko00000 - - - DUF554 CAFIFDFH_01442 405566.lhv_1834 9.25e-288 787.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr CAFIFDFH_01443 326425.lhe_0381 0.0 1192.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,3F4E5@33958|Lactobacillaceae 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N CAFIFDFH_01444 525365.HMPREF0548_1576 2.06e-12 65.5 COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,4HGN9@91061|Bacilli 91061|Bacilli S Fic/DOC family - - - - - - - - - - - - Fic CAFIFDFH_01445 525365.HMPREF0548_1576 8.26e-54 176.0 COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,4HGN9@91061|Bacilli 91061|Bacilli S Fic/DOC family - - - - - - - - - - - - Fic CAFIFDFH_01446 326425.lhe_0379 2.66e-57 177.0 29PFZ@1|root,30AE4@2|Bacteria,1U6IT@1239|Firmicutes,4IGB6@91061|Bacilli,3F800@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun CAFIFDFH_01447 1423748.BALB01000012_gene1200 4e-47 164.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,3F4EG@33958|Lactobacillaceae 91061|Bacilli C L-lactate permease lctP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm CAFIFDFH_01448 1423748.BALB01000012_gene1200 9.79e-111 333.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,3F4EG@33958|Lactobacillaceae 91061|Bacilli C L-lactate permease lctP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm CAFIFDFH_01449 1423748.BALB01000012_gene1200 1e-28 113.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,3F4EG@33958|Lactobacillaceae 91061|Bacilli C L-lactate permease lctP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm CAFIFDFH_01450 405566.lhv_1767 5.84e-134 379.0 COG2755@1|root,COG2755@2|Bacteria,1VB88@1239|Firmicutes,4IPQF@91061|Bacilli,3F5AR@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 CAFIFDFH_01451 326425.lhe_0455 4.75e-220 607.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli,3F42Q@33958|Lactobacillaceae 91061|Bacilli F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK CAFIFDFH_01452 326425.lhe_0456 3.93e-134 380.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F4EW@33958|Lactobacillaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C CAFIFDFH_01453 405566.lhv_1764 9.4e-314 854.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HEKH@91061|Bacilli,3F4P5@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 CAFIFDFH_01454 326425.lhe_0458 1.81e-88 260.0 COG3212@1|root,COG3212@2|Bacteria,1U5TJ@1239|Firmicutes,4IFHH@91061|Bacilli,3F6H2@33958|Lactobacillaceae 91061|Bacilli S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY CAFIFDFH_01456 326425.lhe_0459 2.18e-122 348.0 COG3613@1|root,COG3613@2|Bacteria,1V8XI@1239|Firmicutes,4HJ7M@91061|Bacilli,3FBAU@33958|Lactobacillaceae 91061|Bacilli F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr CAFIFDFH_01457 326425.lhe_0460 1.78e-240 660.0 COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,4HCES@91061|Bacilli,3F5RC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism add - 3.5.4.2,3.5.4.4 ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 M00236 R01244,R01560,R02556 RC00477 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - A_deaminase CAFIFDFH_01458 1423748.BALB01000015_gene1369 1.19e-228 628.0 COG2267@1|root,COG2267@2|Bacteria,1UEDT@1239|Firmicutes,4HF61@91061|Bacilli,3F47H@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepR - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 CAFIFDFH_01459 405566.lhv_1758 0.0 985.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HIAU@91061|Bacilli,3F3JJ@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran CAFIFDFH_01460 405566.lhv_1757 5.69e-182 505.0 COG3201@1|root,COG3201@2|Bacteria,1VE5T@1239|Firmicutes,4HMNW@91061|Bacilli,3F3MB@33958|Lactobacillaceae 91061|Bacilli H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter CAFIFDFH_01461 748671.LCRIS_01678 5.84e-16 73.2 2C9NT@1|root,32ZGB@2|Bacteria,1VG8C@1239|Firmicutes,4HN0V@91061|Bacilli,3F749@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3290) - - - - - - - - - - - - DUF3290 CAFIFDFH_01462 405566.lhv_1756 6.63e-56 176.0 2C9NT@1|root,32ZGB@2|Bacteria,1VG8C@1239|Firmicutes,4HN0V@91061|Bacilli,3F749@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3290) - - - - - - - - - - - - DUF3290 CAFIFDFH_01463 326425.lhe_1603 4.52e-101 293.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,3F65B@33958|Lactobacillaceae 91061|Bacilli J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB CAFIFDFH_01464 326425.lhe_1604 0.0 1495.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,3F4EC@33958|Lactobacillaceae 91061|Bacilli J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 CAFIFDFH_01465 326425.lhe_1605 1.3e-40 134.0 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli,3F7IQ@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG CAFIFDFH_01466 326425.lhe_1606 0.0 1347.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase CAFIFDFH_01467 405566.lhv_0469 1.87e-225 623.0 COG0392@1|root,COG0392@2|Bacteria,1TR9T@1239|Firmicutes,4IQVI@91061|Bacilli,3FBJD@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM CAFIFDFH_01468 326425.lhe_1608 5.23e-256 701.0 COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HB9F@91061|Bacilli,3F47X@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 2.4.1.208 ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 - R05164,R10865 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 CAFIFDFH_01469 326425.lhe_1609 1.19e-279 764.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4IPQK@91061|Bacilli,3FC1E@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase 4-like domain - - 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 CAFIFDFH_01479 405566.lhv_1542 4.58e-117 342.0 COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,4HARI@91061|Bacilli,3F3PC@33958|Lactobacillaceae 91061|Bacilli G -beta-galactosidase lacZ - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M CAFIFDFH_01480 405566.lhv_1542 4.28e-99 295.0 COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,4HARI@91061|Bacilli,3F3PC@33958|Lactobacillaceae 91061|Bacilli G -beta-galactosidase lacZ - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M CAFIFDFH_01481 405566.lhv_1543 0.0 1216.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli,3F3P7@33958|Lactobacillaceae 91061|Bacilli G Transporter lacS - - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 CAFIFDFH_01482 405566.lhv_1543 1.44e-41 153.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli,3F3P7@33958|Lactobacillaceae 91061|Bacilli G Transporter lacS - - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 CAFIFDFH_01483 257314.LJ_0857 3.8e-84 267.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli,3F3P7@33958|Lactobacillaceae 91061|Bacilli G Transporter lacS - - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 CAFIFDFH_01484 525365.HMPREF0548_0295 2.5e-59 199.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli,3F3P7@33958|Lactobacillaceae 91061|Bacilli G Transporter lacS - - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 CAFIFDFH_01485 326425.lhe_1439 1.3e-28 114.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli,3F3P7@33958|Lactobacillaceae 91061|Bacilli G Transporter lacS - - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 CAFIFDFH_01486 405566.lhv_1547 4.7e-237 652.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,3F3PB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator lacR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 CAFIFDFH_01487 405566.lhv_1549 0.0 1319.0 COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,4HANW@91061|Bacilli,3F4EI@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 2 family lacL - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N CAFIFDFH_01488 326425.lhe_1443 3.88e-241 661.0 COG3250@1|root,COG3250@2|Bacteria,1TRVA@1239|Firmicutes,4HFMH@91061|Bacilli,3F51Z@33958|Lactobacillaceae 91061|Bacilli G beta-galactosidase lacM - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N CAFIFDFH_01489 326425.lhe_1444 6.23e-244 669.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,3F3YF@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd CAFIFDFH_01490 405566.lhv_1079 4.46e-226 621.0 COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,4HA4J@91061|Bacilli,3F3KT@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase lacX - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim CAFIFDFH_01491 326425.lhe_0984 3.83e-312 853.0 COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,3F3WB@33958|Lactobacillaceae 91061|Bacilli O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small CAFIFDFH_01492 326425.lhe_0983 5.68e-117 335.0 COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,3F4HS@33958|Lactobacillaceae 91061|Bacilli O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome CAFIFDFH_01493 326425.lhe_0982 1.67e-218 602.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4IQMI@91061|Bacilli,3FBHU@33958|Lactobacillaceae 91061|Bacilli D Phage integrase, N-terminal SAM-like domain xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase CAFIFDFH_01494 326425.lhe_0981 0.0 865.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,3F3WW@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA CAFIFDFH_01495 326425.lhe_0980 0.0 1352.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,3F3VS@33958|Lactobacillaceae 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom CAFIFDFH_01496 326425.lhe_0979 9.46e-199 551.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,3F41U@33958|Lactobacillaceae 91061|Bacilli LU DNA protecting protein DprA dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A CAFIFDFH_01497 326425.lhe_0978 7.68e-173 483.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,3F3JC@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII CAFIFDFH_01498 405566.lhv_1071 6.7e-204 564.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,3F3MI@33958|Lactobacillaceae 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 CAFIFDFH_01499 405566.lhv_1070 0.0 957.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter nhaP4 - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger CAFIFDFH_01500 326425.lhe_0975 9.85e-49 155.0 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli,3F7ZP@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like CAFIFDFH_01501 326425.lhe_0974 2.03e-191 532.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,3FC90@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 degV3 - - - - - - - - - - - DegV CAFIFDFH_01502 326425.lhe_0973 2.1e-151 427.0 COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,3F578@33958|Lactobacillaceae 91061|Bacilli S protein, hemolysin III hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII CAFIFDFH_01503 405566.lhv_1066 1.26e-287 785.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,3F3VH@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 CAFIFDFH_01504 326425.lhe_0971 3.81e-73 226.0 COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli,3FC4M@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 XK27_10395 - - - - - - - - - - - DUF2179,YitT_membrane CAFIFDFH_01505 405566.lhv_1064 2.59e-295 806.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,3F3ND@33958|Lactobacillaceae 91061|Bacilli S Tetratricopeptide repeat protein XK27_05225 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 CAFIFDFH_01506 405566.lhv_1063 8.21e-57 176.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,3F6YN@33958|Lactobacillaceae 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding CAFIFDFH_01507 326425.lhe_0968 7.41e-312 850.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,3F4V0@33958|Lactobacillaceae 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 CAFIFDFH_01508 1423748.BALB01000009_gene1001 1.89e-275 755.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,3F4DQ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 CAFIFDFH_01509 326425.lhe_0966 3.65e-149 421.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,3F3W4@33958|Lactobacillaceae 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin CAFIFDFH_01510 405566.lhv_1059 1.03e-57 185.0 COG1388@1|root,COG1388@2|Bacteria,1W2PN@1239|Firmicutes,4I0F8@91061|Bacilli,3F6G9@33958|Lactobacillaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM CAFIFDFH_01511 405566.lhv_1057 4.7e-143 405.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,3F4HD@33958|Lactobacillaceae 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt CAFIFDFH_01512 326425.lhe_0963 1.1e-166 466.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,3F402@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 CAFIFDFH_01513 405566.lhv_1055 2.85e-135 383.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,3F5RN@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB CAFIFDFH_01514 326425.lhe_0961 3.36e-165 463.0 COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,3F4FS@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA CAFIFDFH_01515 326425.lhe_0960 1.62e-80 238.0 COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,3F7QC@33958|Lactobacillaceae 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ribT - - ko:K02859 - - - - ko00000 - - - Acetyltransf_1,Acetyltransf_10 CAFIFDFH_01516 326425.lhe_0959 1.48e-216 597.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae 91061|Bacilli D recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase CAFIFDFH_01517 405566.lhv_1051 4.41e-216 596.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli,3F44W@33958|Lactobacillaceae 91061|Bacilli S S1 domain yitL - - ko:K00243 - - - - ko00000 - - - S1_2 CAFIFDFH_01518 326425.lhe_0957 0.0 1134.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,3F3JU@33958|Lactobacillaceae 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C CAFIFDFH_01519 405566.lhv_1049 9.45e-234 642.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,3F4CC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iYO844.BSU29190 PFK CAFIFDFH_01520 326425.lhe_0955 0.0 2020.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,3F4AM@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon CAFIFDFH_01521 326425.lhe_0954 1.11e-41 137.0 29PGH@1|root,30AEN@2|Bacteria,1U6JJ@1239|Firmicutes,4IGC1@91061|Bacilli,3F81E@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2929) - - - - - - - - - - - - DUF2929 CAFIFDFH_01522 326425.lhe_0953 0.0 1051.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HC2M@91061|Bacilli,3F45U@33958|Lactobacillaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family yfkN - 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 - R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos CAFIFDFH_01523 1423748.BALB01000010_gene1125 3.62e-38 127.0 COG0333@1|root,COG0333@2|Bacteria,1VKMZ@1239|Firmicutes,4HR2Q@91061|Bacilli,3F7ZT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p CAFIFDFH_01524 326425.lhe_0951 2.25e-34 119.0 COG5416@1|root,COG5416@2|Bacteria,1VIG5@1239|Firmicutes,4HP5V@91061|Bacilli,3F7IW@33958|Lactobacillaceae 91061|Bacilli S Lipopolysaccharide assembly protein A domain - - - - - - - - - - - - LapA_dom CAFIFDFH_01525 405566.lhv_1044 5.86e-184 512.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HI3D@91061|Bacilli,3F41Y@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short CAFIFDFH_01526 326425.lhe_0949 1.05e-226 624.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,3F4F1@33958|Lactobacillaceae 91061|Bacilli J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 CAFIFDFH_01527 405566.lhv_1042 0.0 1202.0 COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,3F3WT@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase oatA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - - - - - - - - - - Acyl_transf_3 CAFIFDFH_01528 326425.lhe_0947 1.55e-308 841.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,3F4ZA@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 CAFIFDFH_01529 326425.lhe_0946 0.0 1191.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,3F3MY@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N CAFIFDFH_01530 1423748.BALB01000010_gene1118 2.26e-70 216.0 COG0586@1|root,COG0586@2|Bacteria,1V2XQ@1239|Firmicutes,4IPZ1@91061|Bacilli,3FBF1@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein yngC - - - - - - - - - - - SNARE_assoc CAFIFDFH_01531 405566.lhv_1029 1.73e-40 138.0 COG0586@1|root,COG0586@2|Bacteria,1V2XQ@1239|Firmicutes,4IPZ1@91061|Bacilli,3FBF1@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein yngC - - - - - - - - - - - SNARE_assoc CAFIFDFH_01532 405566.lhv_1028 0.0 870.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid yhdG - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 CAFIFDFH_01533 1423748.BALB01000010_gene1116 1.35e-54 173.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,3F4Z6@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gyaR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 - R00465,R00717,R01388,R01392,R01739 RC00031,RC00042,RC00084 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C CAFIFDFH_01534 525365.HMPREF0548_0990 1.91e-95 286.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HUAD@91061|Bacilli,3FB6D@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family gyaR - 1.1.1.26,1.1.1.399,1.1.1.95 ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00020 R00717,R01388,R01513 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C CAFIFDFH_01535 1423748.BALB01000010_gene1114 4.08e-106 311.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,3F55S@33958|Lactobacillaceae 91061|Bacilli S hydrolase yxeH - - - - - - - - - - - Hydrolase_3 CAFIFDFH_01536 405566.lhv_1020 1.46e-131 377.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HAG6@91061|Bacilli,3FB4S@33958|Lactobacillaceae 91061|Bacilli S reductase - - - - - - - - - - - - Aldo_ket_red CAFIFDFH_01537 326425.lhe_0941 1.78e-57 184.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HAG6@91061|Bacilli,3FB4S@33958|Lactobacillaceae 91061|Bacilli S reductase - - - - - - - - - - - - Aldo_ket_red CAFIFDFH_01538 326425.lhe_0940 3.7e-279 764.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,3F3XX@33958|Lactobacillaceae 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein CAFIFDFH_01539 326425.lhe_0126 1.33e-145 414.0 2F08C@1|root,33TBR@2|Bacteria,1VR8Q@1239|Firmicutes,4HTKM@91061|Bacilli,3F6XD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01540 1033837.WANG_1665 9.69e-25 92.4 29PIJ@1|root,30AGQ@2|Bacteria,1U6MZ@1239|Firmicutes,4IGEU@91061|Bacilli,3F868@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01541 1033837.WANG_1664 5.56e-21 91.3 COG0584@1|root,COG4781@1|root,COG0584@2|Bacteria,COG4781@2|Bacteria,1UGF1@1239|Firmicutes,4HBM4@91061|Bacilli,3FC1C@33958|Lactobacillaceae 91061|Bacilli C Membrane domain of glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,GPDPase_memb CAFIFDFH_01542 326425.lhe_0123 1.36e-91 268.0 2F916@1|root,341CT@2|Bacteria,1VY7K@1239|Firmicutes,4HX4B@91061|Bacilli,3F70S@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn CAFIFDFH_01543 405566.lhv_0110 1.94e-248 684.0 COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,4HEW7@91061|Bacilli,3F4CJ@33958|Lactobacillaceae 91061|Bacilli P Citrate transporter ysdE - - - - - - - - - - - CitMHS CAFIFDFH_01544 405566.lhv_0109 2.03e-125 357.0 COG1704@1|root,COG1704@2|Bacteria,1V4SV@1239|Firmicutes,4IR1I@91061|Bacilli,3FBKP@33958|Lactobacillaceae 91061|Bacilli S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA CAFIFDFH_01545 405566.lhv_0108 1.92e-206 572.0 COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli,3F40Z@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 CAFIFDFH_01546 1423754.BALY01000006_gene1343 6.02e-85 256.0 COG2963@1|root,COG2963@2|Bacteria,1V1QC@1239|Firmicutes,4HH7E@91061|Bacilli,3F65F@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain - - - - - - - - - - - - HTH_28,HTH_Tnp_1 CAFIFDFH_01547 1423754.BALY01000006_gene1344 2.95e-24 98.2 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,4HD6M@91061|Bacilli,3F43M@33958|Lactobacillaceae 91061|Bacilli L hmm pf00665 - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 CAFIFDFH_01548 1423754.BALY01000006_gene1344 1.25e-10 60.5 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,4HD6M@91061|Bacilli,3F43M@33958|Lactobacillaceae 91061|Bacilli L hmm pf00665 - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 CAFIFDFH_01549 1423754.BALY01000006_gene1344 4.39e-75 233.0 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,4HD6M@91061|Bacilli,3F43M@33958|Lactobacillaceae 91061|Bacilli L hmm pf00665 - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 CAFIFDFH_01550 326425.lhe_0118 1.22e-221 611.0 COG2207@1|root,COG2207@2|Bacteria,1VCUV@1239|Firmicutes,4HGUV@91061|Bacilli,3F48T@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CAFIFDFH_01551 326425.lhe_0117 0.0 882.0 COG0488@1|root,COG0488@2|Bacteria,1UI2R@1239|Firmicutes,4ISG8@91061|Bacilli,3F3WM@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran CAFIFDFH_01552 405566.lhv_0103 1.49e-124 358.0 COG0619@1|root,COG0619@2|Bacteria,1V2VE@1239|Firmicutes,4IPQA@91061|Bacilli,3FBE3@33958|Lactobacillaceae 91061|Bacilli P Cobalt transport protein - - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ CAFIFDFH_01553 326425.lhe_0115 1.75e-225 619.0 COG2267@1|root,COG2267@2|Bacteria,1TRMT@1239|Firmicutes,4HE23@91061|Bacilli,3F40N@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepI - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 CAFIFDFH_01554 326425.lhe_0214 9.89e-159 446.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,3F3YU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CAFIFDFH_01555 891391.LAC30SC_10340 6.79e-137 413.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,3F4HF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease ylbB - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CAFIFDFH_01556 1423748.BALB01000014_gene1333 2.01e-66 214.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,3F4HF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease ylbB - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CAFIFDFH_01557 1423748.BALB01000014_gene1334 1.71e-122 353.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,3F4HF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease ylbB - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CAFIFDFH_01558 326425.lhe_0212 4.81e-50 158.0 2C9N2@1|root,30A73@2|Bacteria,1U6A1@1239|Firmicutes,4IG19@91061|Bacilli,3F7ES@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01559 326425.lhe_0211 0.0 995.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,3F404@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C CAFIFDFH_01560 326425.lhe_0210 1.32e-186 520.0 COG3757@1|root,COG3757@2|Bacteria,1VF8D@1239|Firmicutes,4HX0U@91061|Bacilli,3F4U9@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 lysA2 - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,LysM,SH3_5,SLAP CAFIFDFH_01561 326425.lhe_0209 1.63e-32 117.0 COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,4HPG8@91061|Bacilli,3FBKG@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF975) - - - - - - - - - - - - DUF975 CAFIFDFH_01562 326425.lhe_0209 5.99e-107 311.0 COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,4HPG8@91061|Bacilli,3FBKG@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF975) - - - - - - - - - - - - DUF975 CAFIFDFH_01563 326425.lhe_0208 2.81e-22 86.7 29PVC@1|root,30ATK@2|Bacteria,1U737@1239|Firmicutes,4IGXS@91061|Bacilli,3F8X4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01564 326425.lhe_0207 2.87e-65 200.0 29PJF@1|root,30AHK@2|Bacteria,1U6PF@1239|Firmicutes,4IGGE@91061|Bacilli,3F894@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01565 326425.lhe_0206 1.01e-23 90.5 2CHFN@1|root,30A3Z@2|Bacteria,1U65S@1239|Firmicutes,4IFVM@91061|Bacilli,3F74U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01567 326425.lhe_0205 2.39e-164 460.0 COG1266@1|root,COG1266@2|Bacteria,1VNA9@1239|Firmicutes,4HRMP@91061|Bacilli,3F5T9@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi CAFIFDFH_01568 405566.lhv_0512 3.16e-77 242.0 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli,3F6CN@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 CAFIFDFH_01569 326425.lhe_0939 1.65e-285 780.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspC - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CAFIFDFH_01570 326425.lhe_0938 0.0 1249.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,3F4PE@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon CAFIFDFH_01571 405566.lhv_1013 1.82e-313 853.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,3F3M3@33958|Lactobacillaceae 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His CAFIFDFH_01572 326425.lhe_0936 4.26e-98 285.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,3F6GK@33958|Lactobacillaceae 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase CAFIFDFH_01573 326425.lhe_0935 0.0 1473.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS CAFIFDFH_01574 326425.lhe_0934 2.02e-53 169.0 29PCU@1|root,30AB2@2|Bacteria,1U6F0@1239|Firmicutes,4IG6U@91061|Bacilli,3F7RV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01575 405566.lhv_1009 5.81e-221 610.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,3F47Z@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA CAFIFDFH_01576 326425.lhe_0932 3.74e-115 330.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HHVB@91061|Bacilli,3F5H1@33958|Lactobacillaceae 91061|Bacilli S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit CAFIFDFH_01577 1423748.BALB01000004_gene601 1.25e-102 300.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,Hydrolase_4 CAFIFDFH_01578 326425.lhe_0647 0.0 900.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F4GQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr CAFIFDFH_01579 405566.lhv_0678 5.43e-188 523.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,3F4BY@33958|Lactobacillaceae 91061|Bacilli S Regulatory protein RecX recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX CAFIFDFH_01580 326425.lhe_0649 1.05e-112 323.0 29NVN@1|root,309TR@2|Bacteria,1U5P0@1239|Firmicutes,4IFDJ@91061|Bacilli,3F693@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01581 326425.lhe_0650 2.6e-96 281.0 2C070@1|root,300GJ@2|Bacteria,1U5U1@1239|Firmicutes,4IFHZ@91061|Bacilli,3F6I5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01582 326425.lhe_0651 1.78e-207 573.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3KG@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain hlyX - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 CAFIFDFH_01583 326425.lhe_0652 0.0 1048.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,3F489@33958|Lactobacillaceae 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C CAFIFDFH_01584 326425.lhe_0653 4.17e-60 185.0 2EBZ8@1|root,335YI@2|Bacteria,1VFRS@1239|Firmicutes,4HNUK@91061|Bacilli,3F70G@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1827) XK27_09445 - - - - - - - - - - - DUF1827 CAFIFDFH_01585 405566.lhv_0683 0.0 1360.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F3K9@33958|Lactobacillaceae 91061|Bacilli O Belongs to the ClpA ClpB family clpE - - ko:K03697 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR CAFIFDFH_01586 326425.lhe_0887 0.0 936.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP nadC2 - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase CAFIFDFH_01587 326425.lhe_0886 1.97e-140 395.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli,3F41F@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family pncA - - - - - - - - - - - Isochorismatase CAFIFDFH_01588 1423790.BN53_02275 5.29e-94 289.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,3F4AD@33958|Lactobacillaceae 91061|Bacilli C FAD linked oxidases, C-terminal domain glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 CAFIFDFH_01589 748671.LCRIS_01831 3.71e-137 400.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,3F4AD@33958|Lactobacillaceae 91061|Bacilli C FAD linked oxidases, C-terminal domain glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 CAFIFDFH_01590 1033837.WANG_0698 2.03e-25 103.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 CAFIFDFH_01592 405566.lhv_0924 5.95e-44 147.0 COG2188@1|root,COG2188@2|Bacteria,1V0UW@1239|Firmicutes,4HI7E@91061|Bacilli,3F4BH@33958|Lactobacillaceae 91061|Bacilli K UTRA domain - - - ko:K03492 - - - - ko00000,ko03000 - - - GntR,UTRA CAFIFDFH_01593 326425.lhe_0884 9.39e-94 276.0 COG2188@1|root,COG2188@2|Bacteria,1V0UW@1239|Firmicutes,4HI7E@91061|Bacilli,3F4BH@33958|Lactobacillaceae 91061|Bacilli K UTRA domain - - - ko:K03492 - - - - ko00000,ko03000 - - - GntR,UTRA CAFIFDFH_01594 1423748.BALB01000019_gene1571 0.0 968.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family pbg4 - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 CAFIFDFH_01595 326425.lhe_0882 1.64e-202 561.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,3F4U1@33958|Lactobacillaceae 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red CAFIFDFH_01596 405566.lhv_0918 3.39e-226 622.0 COG1957@1|root,COG1957@2|Bacteria,1TRGU@1239|Firmicutes,4H9TZ@91061|Bacilli,3F3V1@33958|Lactobacillaceae 91061|Bacilli F inosine-uridine preferring nucleoside hydrolase iunH - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro CAFIFDFH_01597 326425.lhe_0880 8.69e-106 306.0 2F7PX@1|root,34049@2|Bacteria,1UFVR@1239|Firmicutes,4IEZD@91061|Bacilli,3F548@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01598 272621.LBA0861 2.17e-05 43.9 COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,4IT3F@91061|Bacilli,3F7II@33958|Lactobacillaceae 91061|Bacilli C FMN_bind - - - - - - - - - - - - FMN_bind CAFIFDFH_01599 405566.lhv_2039 1.76e-312 853.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yifK - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease CAFIFDFH_01600 326425.lhe_0220 1.95e-307 840.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease aapA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease CAFIFDFH_01601 326425.lhe_0219 3.59e-164 461.0 29V9A@1|root,30GPA@2|Bacteria,1UGDF@1239|Firmicutes,4IF6B@91061|Bacilli,3F5SI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01602 326425.lhe_0218 2.07e-154 433.0 COG0681@1|root,COG0681@2|Bacteria,1TRAV@1239|Firmicutes,4HCTU@91061|Bacilli,3FBKX@33958|Lactobacillaceae 91061|Bacilli U Belongs to the peptidase S26 family sipS3 - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 CAFIFDFH_01603 326425.lhe_0217 0.0 1346.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F5GX@33958|Lactobacillaceae 91061|Bacilli O AAA domain (Cdc48 subfamily) clpE - - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR CAFIFDFH_01604 326425.lhe_0216 1.22e-218 603.0 COG4814@1|root,COG4814@2|Bacteria,1V8NG@1239|Firmicutes,4HJ22@91061|Bacilli,3F41V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 CAFIFDFH_01605 326425.lhe_0215 4.63e-277 760.0 COG1455@1|root,COG1455@2|Bacteria,1V5SI@1239|Firmicutes,4HJTK@91061|Bacilli,3F3Z5@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts13C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC CAFIFDFH_01606 1423790.BN53_01845 3.22e-169 485.0 COG1455@1|root,COG1455@2|Bacteria,1VTVX@1239|Firmicutes,4HFKM@91061|Bacilli,3FC6X@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts23C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC CAFIFDFH_01607 326425.lhe_0892 3.85e-237 656.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HDER@91061|Bacilli,3FC7C@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family pbg6 - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 CAFIFDFH_01608 326425.lhe_0892 2.57e-102 307.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HDER@91061|Bacilli,3FC7C@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family pbg6 - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 CAFIFDFH_01609 1423748.BALB01000019_gene1559 3.58e-101 299.0 COG1940@1|root,COG1940@2|Bacteria,1UZ80@1239|Firmicutes,4HD5J@91061|Bacilli,3FBD4@33958|Lactobacillaceae 91061|Bacilli GK ROK family ypbG - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK CAFIFDFH_01610 1423748.BALB01000019_gene1559 5.95e-14 70.1 COG1940@1|root,COG1940@2|Bacteria,1UZ80@1239|Firmicutes,4HD5J@91061|Bacilli,3FBD4@33958|Lactobacillaceae 91061|Bacilli GK ROK family ypbG - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK CAFIFDFH_01611 405566.lhv_0943 8.27e-111 318.0 COG0778@1|root,COG0778@2|Bacteria,1UYXM@1239|Firmicutes,4HD96@91061|Bacilli,3F667@33958|Lactobacillaceae 91061|Bacilli C nitroreductase yfhC - - - - - - - - - - - Nitroreductase CAFIFDFH_01612 326425.lhe_0895 1.98e-101 297.0 29W71@1|root,30HS8@2|Bacteria,1VZSI@1239|Firmicutes,4IFNQ@91061|Bacilli,3F6RP@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4767) - - - - - - - - - - - - DUF4767 CAFIFDFH_01613 326425.lhe_0896 6.08e-312 849.0 COG0148@1|root,COG0148@2|Bacteria,1V12I@1239|Firmicutes,4HTD2@91061|Bacilli,3FCCA@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0043236,GO:0050840 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N CAFIFDFH_01614 748671.LCRIS_00904 1.26e-166 469.0 COG1307@1|root,COG1307@2|Bacteria,1V0RC@1239|Firmicutes,4HBSA@91061|Bacilli,3F4PM@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 - - - - - - - - - - - - DegV CAFIFDFH_01615 405566.lhv_0949 1.08e-127 363.0 COG0671@1|root,COG0671@2|Bacteria,1U506@1239|Firmicutes,4IES2@91061|Bacilli,3F3M2@33958|Lactobacillaceae 91061|Bacilli I PAP2 superfamily - - - - - - - - - - - - PAP2 CAFIFDFH_01616 891391.LAC30SC_04505 6.49e-147 419.0 COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,4HC4Y@91061|Bacilli,3F4NH@33958|Lactobacillaceae 91061|Bacilli M Linear amide C-N hydrolase, choloylglycine hydrolase family protein cbh - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH CAFIFDFH_01617 405566.lhv_0628 1.42e-170 477.0 COG1349@1|root,COG1349@2|Bacteria,1V1VH@1239|Firmicutes,4HG12@91061|Bacilli,3F3UT@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR CAFIFDFH_01618 326425.lhe_0563 5.17e-83 245.0 29P3Y@1|root,30A25@2|Bacteria,1U639@1239|Firmicutes,4IFSM@91061|Bacilli,3F6XR@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun CAFIFDFH_01619 405566.lhv_0626 8.76e-73 218.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,3F7D5@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein yitW - - - - - - - - - - - FeS_assembly_P CAFIFDFH_01620 326425.lhe_0561 0.0 937.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,3F44I@33958|Lactobacillaceae 91061|Bacilli O assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 CAFIFDFH_01621 326425.lhe_0560 1.29e-105 305.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,3F6WP@33958|Lactobacillaceae 91061|Bacilli C SUF system FeS assembly protein, NifU family nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N CAFIFDFH_01622 405566.lhv_0623 3.17e-299 816.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,3F3UP@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 CAFIFDFH_01623 326425.lhe_0558 1.21e-305 833.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,3F4BR@33958|Lactobacillaceae 91061|Bacilli O FeS assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 CAFIFDFH_01624 405566.lhv_0621 1.5e-186 518.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,3F3XT@33958|Lactobacillaceae 91061|Bacilli O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran CAFIFDFH_01625 405566.lhv_0620 1.82e-29 108.0 COG3039@1|root,COG3039@2|Bacteria,1UZVA@1239|Firmicutes,4HH09@91061|Bacilli,3F4KP@33958|Lactobacillaceae 91061|Bacilli L An automated process has identified a potential problem with this gene model - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_3 CAFIFDFH_01626 405566.lhv_0620 2.36e-51 166.0 COG3039@1|root,COG3039@2|Bacteria,1UZVA@1239|Firmicutes,4HH09@91061|Bacilli,3F4KP@33958|Lactobacillaceae 91061|Bacilli L An automated process has identified a potential problem with this gene model - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_3 CAFIFDFH_01627 326425.lhe_0595 7.22e-198 548.0 COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,4HWAW@91061|Bacilli,3F3Z7@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 CAFIFDFH_01628 405566.lhv_0617 1.84e-63 194.0 COG2746@1|root,COG2746@2|Bacteria,1V2QD@1239|Firmicutes,4HC3S@91061|Bacilli,3F635@33958|Lactobacillaceae 91061|Bacilli V Aminoglycoside 3-N-acetyltransferase - - 2.3.1.81 ko:K00662 - - - - ko00000,ko01000,ko01504 - - - Antibiotic_NAT CAFIFDFH_01629 326425.lhe_1458 1.22e-218 603.0 COG2971@1|root,COG2971@2|Bacteria,1V38W@1239|Firmicutes,4HGPI@91061|Bacilli,3F5MG@33958|Lactobacillaceae 91061|Bacilli G BadF/BadG/BcrA/BcrD ATPase family - - - - - - - - - - - - BcrAD_BadFG CAFIFDFH_01630 326425.lhe_1457 0.0 1640.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HBW6@91061|Bacilli,3F49G@33958|Lactobacillaceae 91061|Bacilli S membrane - - - - - - - - - - - - YfhO CAFIFDFH_01631 326425.lhe_1456 0.0 1365.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,3F3KH@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbp2b - - ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase CAFIFDFH_01632 1423748.BALB01000003_gene424 6.25e-29 103.0 COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,4HNIM@91061|Bacilli,3F828@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 CAFIFDFH_01633 326425.lhe_1454 3.12e-129 367.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HKQI@91061|Bacilli,3FC8W@33958|Lactobacillaceae 91061|Bacilli H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family fthC - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig CAFIFDFH_01634 405566.lhv_1567 3.26e-153 431.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,3FC8V@33958|Lactobacillaceae 91061|Bacilli S Rhomboid family gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 CAFIFDFH_01635 326425.lhe_1452 7.03e-44 142.0 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli,3F83I@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF910) yqgQ - - - - - - - - - - - DUF910 CAFIFDFH_01636 326425.lhe_1451 1.26e-91 268.0 COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,3F67E@33958|Lactobacillaceae 91061|Bacilli P Rhodanese-like protein yqhL - - - - - - - - - - - Rhodanese CAFIFDFH_01637 326425.lhe_1450 1.17e-220 608.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,3F3XS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT CAFIFDFH_01638 326425.lhe_0817 1.97e-124 354.0 29NQT@1|root,309NS@2|Bacteria,1U5E6@1239|Firmicutes,4IF5G@91061|Bacilli,3F5PM@33958|Lactobacillaceae 91061|Bacilli - - mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD CAFIFDFH_01639 405566.lhv_0846 1.74e-190 530.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,3F3MC@33958|Lactobacillaceae 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC CAFIFDFH_01640 326425.lhe_0815 2.12e-228 630.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F3ZV@33958|Lactobacillaceae 91061|Bacilli D cell shape determining protein MreB mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl CAFIFDFH_01641 326425.lhe_0814 3.32e-148 417.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,3F5IM@33958|Lactobacillaceae 91061|Bacilli L DNA repair protein radC - - ko:K03630 - - - - ko00000 - - - RadC CAFIFDFH_01642 326425.lhe_0813 1.29e-163 457.0 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli,3F56K@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 CAFIFDFH_01643 326425.lhe_0812 2.64e-304 830.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,3F498@33958|Lactobacillaceae 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M CAFIFDFH_01644 326425.lhe_0811 0.0 1811.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,3F3RB@33958|Lactobacillaceae 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 CAFIFDFH_01645 405566.lhv_0986 1.46e-46 161.0 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli,3F6CN@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 CAFIFDFH_01646 1033837.WANG_0664 2.52e-73 232.0 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli,3F54U@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 CAFIFDFH_01647 326425.lhe_0988 7.18e-86 253.0 COG0239@1|root,COG0239@2|Bacteria,1U4G6@1239|Firmicutes,4IE88@91061|Bacilli,3F6R4@33958|Lactobacillaceae 91061|Bacilli U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB1 - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB CAFIFDFH_01648 326425.lhe_0989 2.08e-84 249.0 COG0239@1|root,COG0239@2|Bacteria,1VM30@1239|Firmicutes,4HRC4@91061|Bacilli,3F8A8@33958|Lactobacillaceae 91061|Bacilli U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB CAFIFDFH_01649 1423748.BALB01000009_gene1032 9.88e-39 133.0 COG5015@1|root,COG5015@2|Bacteria,1TR2Q@1239|Firmicutes,4HHXT@91061|Bacilli,3F66T@33958|Lactobacillaceae 91061|Bacilli C Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Fer4,Putative_PNPOx CAFIFDFH_01650 1423748.BALB01000009_gene1032 4.53e-57 180.0 COG5015@1|root,COG5015@2|Bacteria,1TR2Q@1239|Firmicutes,4HHXT@91061|Bacilli,3F66T@33958|Lactobacillaceae 91061|Bacilli C Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Fer4,Putative_PNPOx CAFIFDFH_01651 1423748.BALB01000009_gene1033 9.4e-235 652.0 COG0531@1|root,COG0531@2|Bacteria,1UYSD@1239|Firmicutes,4IPMN@91061|Bacilli,3F48U@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 CAFIFDFH_01652 405566.lhv_1093 0.0 1399.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,3F3TV@33958|Lactobacillaceae 91061|Bacilli E Orn/Lys/Arg decarboxylase, C-terminal domain speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.17,4.1.1.18,4.1.1.19 ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 M00133,M00134 R00462,R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C CAFIFDFH_01653 326425.lhe_0997 1.27e-313 853.0 COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,3F3PU@33958|Lactobacillaceae 91061|Bacilli P aluminum resistance ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - - - - - - - - - - Met_gamma_lyase CAFIFDFH_01654 326425.lhe_0998 0.0 1168.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3F4PY@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind CAFIFDFH_01655 326425.lhe_0999 2.35e-106 306.0 COG0716@1|root,COG0716@2|Bacteria,1V465@1239|Firmicutes,4HN5X@91061|Bacilli,3F7H7@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin - - - - - - - - - - - - Flavodoxin_4 CAFIFDFH_01656 326425.lhe_1000 2.32e-145 410.0 COG0671@1|root,COG0671@2|Bacteria,1V7XD@1239|Firmicutes,4IPZ9@91061|Bacilli,3FBEV@33958|Lactobacillaceae 91061|Bacilli I Acid phosphatase homologues - - - - - - - - - - - - PAP2 CAFIFDFH_01657 326425.lhe_1001 1.46e-145 410.0 COG0110@1|root,COG0110@2|Bacteria,1V06U@1239|Firmicutes,4IPZB@91061|Bacilli,3FBEW@33958|Lactobacillaceae 91061|Bacilli S transferase hexapeptide repeat maa3 - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac CAFIFDFH_01658 405566.lhv_1103 6.46e-266 728.0 COG1680@1|root,COG1680@2|Bacteria,1U52D@1239|Firmicutes,4IETU@91061|Bacilli,3F440@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CAFIFDFH_01659 405566.lhv_1104 3.17e-193 536.0 COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli,3F3V7@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin CAFIFDFH_01660 405566.lhv_1105 2.46e-121 347.0 COG4720@1|root,COG4720@2|Bacteria,1V52B@1239|Firmicutes,4HKM2@91061|Bacilli,3F4W9@33958|Lactobacillaceae 91061|Bacilli S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS CAFIFDFH_01661 405566.lhv_1106 1.01e-294 803.0 COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,4HDTN@91061|Bacilli,3F3QW@33958|Lactobacillaceae 91061|Bacilli S Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_4,YkuD CAFIFDFH_01662 405566.lhv_1107 6.97e-301 823.0 COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,4HEHY@91061|Bacilli,3F3KX@33958|Lactobacillaceae 91061|Bacilli V MATE efflux family protein mepA - - ko:K18908 - M00705 - - ko00000,ko00002,ko01504,ko02000 2.A.66.1.13 - - MatE CAFIFDFH_01663 326425.lhe_1007 0.0 887.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,3F45V@33958|Lactobacillaceae 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CAFIFDFH_01664 326425.lhe_1008 3.36e-46 148.0 2AR8Z@1|root,31GIU@2|Bacteria,1U6P4@1239|Firmicutes,4IGG4@91061|Bacilli,3F88G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_26 CAFIFDFH_01665 1423748.BALB01000009_gene1051 4.31e-40 137.0 COG2184@1|root,COG2184@2|Bacteria,1VK13@1239|Firmicutes,4IQYB@91061|Bacilli,3F711@33958|Lactobacillaceae 91061|Bacilli D Fic/DOC family - - - ko:K04095 - - - - ko00000,ko03036 - - - Fic CAFIFDFH_01666 1423748.BALB01000009_gene1052 4.01e-80 237.0 29P12@1|root,309Z7@2|Bacteria,1U5Z5@1239|Firmicutes,4IFN5@91061|Bacilli,3F6QZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01667 405566.lhv_1111 0.0 1011.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F514@33958|Lactobacillaceae 91061|Bacilli P ABC transporter - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran CAFIFDFH_01668 405566.lhv_1112 0.0 1015.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F46B@33958|Lactobacillaceae 91061|Bacilli V ABC-type multidrug transport system, ATPase and permease components - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran CAFIFDFH_01669 405566.lhv_1113 1.18e-126 365.0 COG3595@1|root,COG3595@2|Bacteria,1VKFR@1239|Firmicutes,4HRQ4@91061|Bacilli,3F4TV@33958|Lactobacillaceae 91061|Bacilli S Putative adhesin - - - ko:K11621 ko02020,map02020 - - - ko00000,ko00001 - - - DUF4097 CAFIFDFH_01670 405566.lhv_1114 2.68e-53 169.0 COG3759@1|root,COG3759@2|Bacteria,1VAVU@1239|Firmicutes,4HQHN@91061|Bacilli,3F7NA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1304) - - - ko:K08987 - - - - ko00000 - - - DUF1304 CAFIFDFH_01671 326425.lhe_1011 4.77e-118 338.0 2C5CP@1|root,30ANW@2|Bacteria,1U6XC@1239|Firmicutes,4IGRM@91061|Bacilli,3F8NS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01672 326425.lhe_1012 4.35e-88 260.0 29NX2@1|root,309V6@2|Bacteria,1U5S0@1239|Firmicutes,4IFGA@91061|Bacilli,3F6ET@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01673 326425.lhe_1013 1.54e-141 399.0 COG3177@1|root,COG3177@2|Bacteria,1V3AX@1239|Firmicutes,4HVK3@91061|Bacilli,3F4YX@33958|Lactobacillaceae 91061|Bacilli S Fic/DOC family - - - - - - - - - - - - Fic CAFIFDFH_01674 326425.lhe_1014 4.75e-132 375.0 2A1GN@1|root,30PQ9@2|Bacteria,1U5RF@1239|Firmicutes,4IFFK@91061|Bacilli,3F6DA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01675 326425.lhe_1015 1.19e-120 353.0 COG0477@1|root,COG2814@2|Bacteria,1W01A@1239|Firmicutes,4HZ1U@91061|Bacilli,3F4S8@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CAFIFDFH_01676 405566.lhv_1119 3.48e-56 185.0 COG0477@1|root,COG2814@2|Bacteria,1W01A@1239|Firmicutes,4HZ1U@91061|Bacilli,3F4S8@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CAFIFDFH_01677 405566.lhv_1120 1.24e-171 478.0 2C6BP@1|root,32SQP@2|Bacteria,1VDYG@1239|Firmicutes,4HS7C@91061|Bacilli,3F5TH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01678 326425.lhe_1017 2.08e-59 184.0 29P75@1|root,30A58@2|Bacteria,1U67S@1239|Firmicutes,4IFYB@91061|Bacilli,3F79M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01679 326425.lhe_1018 3.71e-105 303.0 COG0454@1|root,COG0456@2|Bacteria,1V125@1239|Firmicutes,4HFVJ@91061|Bacilli,3F5TK@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10,Acetyltransf_7 CAFIFDFH_01681 405566.lhv_1123 9.45e-99 286.0 COG0295@1|root,COG0295@2|Bacteria,1V7IK@1239|Firmicutes,4HMND@91061|Bacilli,3FC88@33958|Lactobacillaceae 91061|Bacilli F Cytidine and deoxycytidylate deaminase zinc-binding region codA - - - - - - - - - - - dCMP_cyt_deam_1 CAFIFDFH_01682 405566.lhv_1124 1.51e-185 515.0 COG2820@1|root,COG2820@2|Bacteria,1TQ71@1239|Firmicutes,4IRA8@91061|Bacilli,3F3UX@33958|Lactobacillaceae 91061|Bacilli F Phosphorylase superfamily - - - - - - - - - - - - PNP_UDP_1 CAFIFDFH_01683 405566.lhv_1125 1.58e-40 135.0 29PM0@1|root,30AJ6@2|Bacteria,1U6RS@1239|Firmicutes,4IGJ8@91061|Bacilli,3F8DP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01684 326425.lhe_1027 2.73e-60 185.0 COG2161@1|root,COG2161@2|Bacteria,1U6CD@1239|Firmicutes,4IG41@91061|Bacilli,3F7KJ@33958|Lactobacillaceae 91061|Bacilli D Antitoxin component of a toxin-antitoxin (TA) module - - - ko:K19159 - - - - ko00000,ko02048 - - - PhdYeFM_antitox CAFIFDFH_01685 326425.lhe_1028 1.3e-80 238.0 COG3041@1|root,COG3041@2|Bacteria,1U6BU@1239|Firmicutes,4IG3F@91061|Bacilli,3F7JG@33958|Lactobacillaceae 91061|Bacilli S Bacterial toxin of type II toxin-antitoxin system, YafQ - - - - - - - - - - - - YafQ_toxin CAFIFDFH_01688 525365.HMPREF0548_1209 1.25e-149 426.0 COG0789@1|root,COG0789@2|Bacteria,1TS86@1239|Firmicutes,4HJAU@91061|Bacilli,3F6G4@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 CAFIFDFH_01689 326425.lhe_1031 5.75e-124 352.0 COG0454@1|root,COG0456@2|Bacteria,1V6YX@1239|Firmicutes,4IQXU@91061|Bacilli,3F6BG@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 CAFIFDFH_01690 326425.lhe_1032 0.0 1658.0 COG0178@1|root,COG0178@2|Bacteria,1TP0A@1239|Firmicutes,4HTDZ@91061|Bacilli,3F3V4@33958|Lactobacillaceae 91061|Bacilli L excinuclease ABC, A subunit uvrA2 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - AAA_21,ABC_tran CAFIFDFH_01691 525318.HMPREF0497_1541 6.28e-08 52.4 29PWG@1|root,30AUU@2|Bacteria,1U74Q@1239|Firmicutes,4IGZC@91061|Bacilli,3F8Z1@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3923) - - - - - - - - - - - - DUF3923 CAFIFDFH_01693 405566.lhv_1133 1.1e-136 387.0 COG0127@1|root,COG0127@2|Bacteria,1U7FQ@1239|Firmicutes,4IHBR@91061|Bacilli,3F9JR@33958|Lactobacillaceae 91061|Bacilli F Ham1 family - - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like CAFIFDFH_01694 326425.lhe_1036 1.96e-98 286.0 COG3279@1|root,COG3279@2|Bacteria,1VD10@1239|Firmicutes,4HMF3@91061|Bacilli,3F6QC@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR CAFIFDFH_01695 326425.lhe_1037 9.74e-98 284.0 2A0WQ@1|root,30P1T@2|Bacteria,1U66T@1239|Firmicutes,4IFX9@91061|Bacilli,3F77R@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 CAFIFDFH_01696 1423748.BALB01000031_gene1923 0.0 922.0 COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,4HBFK@91061|Bacilli,3F53D@33958|Lactobacillaceae 91061|Bacilli S ABC transporter yjcA - - ko:K19350 ko02010,map02010 - - - ko00000,ko00001,ko01504,ko02000 3.A.1.121 - - ABC_tran,ABC_tran_Xtn CAFIFDFH_01697 1033837.WANG_1559 1.25e-293 808.0 COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,3FBEE@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic tcaA - - ko:K21463 - - - - ko00000 - - - zf-ribbon_3,zinc_ribbon_2 CAFIFDFH_01698 405566.lhv_1483 3.09e-118 338.0 29NJI@1|root,309HE@2|Bacteria,1U53J@1239|Firmicutes,4IEUW@91061|Bacilli,3F4CT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01699 525365.HMPREF0548_0256 2.37e-148 434.0 2FIUN@1|root,34AK2@2|Bacteria,1W1FZ@1239|Firmicutes,4HYXZ@91061|Bacilli,3F4EU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Big_3,SH3_8 CAFIFDFH_01700 405566.lhv_1486 1.6e-138 395.0 29NM6@1|root,309J4@2|Bacteria,1U575@1239|Firmicutes,4IEYP@91061|Bacilli,3F507@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01701 326425.lhe_1401 9.3e-162 453.0 COG0656@1|root,COG0656@2|Bacteria,1U59X@1239|Firmicutes,4IF1F@91061|Bacilli,3F5BI@33958|Lactobacillaceae 91061|Bacilli S L-ascorbic acid biosynthetic process - - - - - - - - - - - - Aldo_ket_red CAFIFDFH_01702 326425.lhe_1402 1.07e-93 273.0 COG1765@1|root,COG1765@2|Bacteria,1VN90@1239|Firmicutes,4HRIC@91061|Bacilli,3F6MQ@33958|Lactobacillaceae 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC CAFIFDFH_01703 405566.lhv_1489 6.45e-265 727.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HX8J@91061|Bacilli,3F43Q@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CAFIFDFH_01704 1423748.BALB01000003_gene466 2.42e-148 427.0 COG0642@1|root,COG0642@2|Bacteria,1UHQH@1239|Firmicutes,4HAHG@91061|Bacilli,3F4JY@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase sptS - - - - - - - - - - - HATPase_c,HisKA CAFIFDFH_01705 1423748.BALB01000003_gene466 1.81e-42 149.0 COG0642@1|root,COG0642@2|Bacteria,1UHQH@1239|Firmicutes,4HAHG@91061|Bacilli,3F4JY@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase sptS - - - - - - - - - - - HATPase_c,HisKA CAFIFDFH_01706 1423748.BALB01000003_gene465 1.02e-43 147.0 COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,4HG2E@91061|Bacilli,3F53G@33958|Lactobacillaceae 91061|Bacilli K response regulator dltr - - - - - - - - - - - Response_reg,Trans_reg_C CAFIFDFH_01707 326425.lhe_0196 4.13e-35 119.0 COG0517@1|root,COG0517@2|Bacteria 2|Bacteria S IMP dehydrogenase activity ykuL - - - - - - - - - - - CBS CAFIFDFH_01708 326425.lhe_0197 1.89e-276 755.0 COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,4HITC@91061|Bacilli,3F50M@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - CAFIFDFH_01709 326425.lhe_0198 9.91e-68 204.0 29P6X@1|root,30A50@2|Bacteria,1U67F@1239|Firmicutes,4IFXY@91061|Bacilli,3F78Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01710 525365.HMPREF0548_1419 6.46e-27 98.2 2DKQV@1|root,30ADX@2|Bacteria,1U6IK@1239|Firmicutes,4IGAZ@91061|Bacilli,3F7ZM@33958|Lactobacillaceae 91061|Bacilli S D-Ala-teichoic acid biosynthesis protein - - - - - - - - - - - - DUF3687 CAFIFDFH_01711 405566.lhv_2060 0.0 1019.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,3F49R@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - AMP-binding,AMP-binding_C CAFIFDFH_01712 405566.lhv_2059 1.12e-308 840.0 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,3F4KK@33958|Lactobacillaceae 91061|Bacilli M MBOAT, membrane-bound O-acyltransferase family dltB - - ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - MBOAT CAFIFDFH_01713 326425.lhe_0202 2.46e-48 154.0 COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli,3F7Q1@33958|Lactobacillaceae 91061|Bacilli J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding CAFIFDFH_01714 326425.lhe_0203 9.71e-317 862.0 COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli,3F3WE@33958|Lactobacillaceae 91061|Bacilli M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) dltD - - ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - DltD CAFIFDFH_01715 1423748.BALB01000014_gene1342 1.38e-223 616.0 COG1680@1|root,COG1680@2|Bacteria,1V0GX@1239|Firmicutes,4HCXH@91061|Bacilli,3F4TH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX2 - - - - - - - - - - - Beta-lactamase CAFIFDFH_01716 326425.lhe_0516 2.03e-92 270.0 2F916@1|root,309SE@2|Bacteria,1U5KS@1239|Firmicutes,4IFBR@91061|Bacilli,3F65Y@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn CAFIFDFH_01717 326425.lhe_0517 1.52e-43 141.0 2C7HR@1|root,30AK4@2|Bacteria,1U6T5@1239|Firmicutes,4IGKW@91061|Bacilli,3F8FZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01718 405566.lhv_0520 1.09e-86 255.0 2C7EH@1|root,30A2S@2|Bacteria,1U643@1239|Firmicutes,4IFTN@91061|Bacilli,3F6ZP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01719 1423748.BALB01000016_gene1455 2.07e-37 133.0 COG0639@1|root,COG0639@2|Bacteria,1V1HN@1239|Firmicutes,4HF40@91061|Bacilli,3F401@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase pphA - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos CAFIFDFH_01720 1423748.BALB01000016_gene1455 2.31e-61 195.0 COG0639@1|root,COG0639@2|Bacteria,1V1HN@1239|Firmicutes,4HF40@91061|Bacilli,3F401@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase pphA - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos CAFIFDFH_01721 1423748.BALB01000016_gene1455 4e-32 119.0 COG0639@1|root,COG0639@2|Bacteria,1V1HN@1239|Firmicutes,4HF40@91061|Bacilli,3F401@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase pphA - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos CAFIFDFH_01722 1423748.BALB01000016_gene1454 5.26e-19 77.4 29PR7@1|root,30APF@2|Bacteria,1U6Y4@1239|Firmicutes,4IGSA@91061|Bacilli,3F8PS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01723 405566.lhv_0523 7.95e-136 387.0 COG1388@1|root,COG1388@2|Bacteria,1V773@1239|Firmicutes,4HIJG@91061|Bacilli,3F3JQ@33958|Lactobacillaceae 91061|Bacilli M LysM domain protein - - - - - - - - - - - - LysM,SLAP CAFIFDFH_01724 405566.lhv_0524 7.08e-250 686.0 COG1196@1|root,COG1196@2|Bacteria,1U570@1239|Firmicutes,4IEYI@91061|Bacilli,3F4ZJ@33958|Lactobacillaceae 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - - CAFIFDFH_01725 405566.lhv_0525 3.79e-142 400.0 COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli,3F4JB@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 CAFIFDFH_01726 405566.lhv_0526 7.66e-292 796.0 COG0406@1|root,COG1359@1|root,COG0406@2|Bacteria,COG1359@2|Bacteria,1VVR5@1239|Firmicutes,4HWFJ@91061|Bacilli,3F5NS@33958|Lactobacillaceae 91061|Bacilli G Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM,His_Phos_1 CAFIFDFH_01727 326425.lhe_0525 1.45e-172 480.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,3F4E3@33958|Lactobacillaceae 91061|Bacilli C glycerophosphoryl diester phosphodiesterase glpQ1 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD CAFIFDFH_01728 1033837.WANG_1781 2.93e-196 544.0 COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,4HB46@91061|Bacilli,3F58H@33958|Lactobacillaceae 91061|Bacilli H Quinolinate phosphoribosyl transferase, C-terminal domain nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N CAFIFDFH_01729 1033837.WANG_1782 3.43e-267 733.0 COG0477@1|root,COG2814@2|Bacteria,1TQM0@1239|Firmicutes,4HATA@91061|Bacilli,3F3SE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator yceI - - ko:K08369 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr CAFIFDFH_01730 387344.LVIS_0121 7.67e-223 614.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve CAFIFDFH_01731 1140001.I571_02837 1.31e-287 786.0 COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli,4AZGP@81852|Enterococcaceae 91061|Bacilli P Major Facilitator Superfamily oxlT - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 CAFIFDFH_01732 1123359.AUIQ01000085_gene536 1.31e-29 110.0 COG2963@1|root,COG2963@2|Bacteria,1V35U@1239|Firmicutes,4HHRN@91061|Bacilli,4B6SW@81852|Enterococcaceae 91061|Bacilli L Helix-turn-helix domain - - - ko:K07483,ko:K07497 - - - - ko00000 - - - HTH_28,HTH_Tnp_1 CAFIFDFH_01733 326425.lhe_0246 1.15e-224 620.0 COG1609@1|root,COG1609@2|Bacteria,1U6Z4@1239|Firmicutes,4HC2A@91061|Bacilli,3F3ZC@33958|Lactobacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor yvdE - - - - - - - - - - - LacI,Peripla_BP_3 CAFIFDFH_01734 326425.lhe_0025 4.24e-216 595.0 COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,4HA1C@91061|Bacilli,3F3K8@33958|Lactobacillaceae 91061|Bacilli GK ROK family scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK CAFIFDFH_01735 326425.lhe_0026 0.000255 41.6 29PGN@1|root,30AET@2|Bacteria,1U6JR@1239|Firmicutes,4IGC8@91061|Bacilli,3F81J@33958|Lactobacillaceae 91061|Bacilli S CsbD-like - - - - - - - - - - - - CsbD CAFIFDFH_01736 1423767.BALU01000001_gene1631 1.31e-35 122.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc CAFIFDFH_01737 405566.lhv_0025 4.52e-302 823.0 COG2267@1|root,COG2267@2|Bacteria,1UHVZ@1239|Firmicutes,4ISGG@91061|Bacilli,3F3SU@33958|Lactobacillaceae 91061|Bacilli I Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 CAFIFDFH_01738 405566.lhv_0026 2.28e-157 442.0 COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,4HK8H@91061|Bacilli,3F3QE@33958|Lactobacillaceae 91061|Bacilli S MgtC family - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC CAFIFDFH_01740 326425.lhe_0041 5.23e-45 145.0 29P9K@1|root,30A7Q@2|Bacteria,1U6AW@1239|Firmicutes,4IG2B@91061|Bacilli,3F7H3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01742 326425.lhe_0043 1.21e-40 134.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli,3F85E@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 CAFIFDFH_01743 326425.lhe_0044 1.34e-145 410.0 COG4619@1|root,COG4619@2|Bacteria,1V3DQ@1239|Firmicutes,4HHGU@91061|Bacilli,3F4UY@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ybbL - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran CAFIFDFH_01744 326425.lhe_0045 1.36e-167 469.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,3F4P1@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0014) ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 CAFIFDFH_01745 326425.lhe_0372 6.73e-302 834.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F44C@33958|Lactobacillaceae 91061|Bacilli GT Phosphotransferase System fruA - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB CAFIFDFH_01746 326425.lhe_0373 2.19e-56 175.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,3F72A@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 CAFIFDFH_01747 405566.lhv_1842 5.71e-218 603.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli,3F4B9@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA CAFIFDFH_01748 405566.lhv_1841 4.01e-153 430.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,3F49M@33958|Lactobacillaceae 91061|Bacilli P ABC transporter adcC - - ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 M00242,M00244,M00319 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU02860 ABC_tran CAFIFDFH_01749 326425.lhe_0376 5.54e-173 484.0 COG1108@1|root,COG1108@2|Bacteria,1V0SX@1239|Firmicutes,4HE09@91061|Bacilli,3F4BC@33958|Lactobacillaceae 91061|Bacilli U ABC 3 transport family znuB - - ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 CAFIFDFH_01750 405566.lhv_1839 6.92e-304 832.0 COG1823@1|root,COG1823@2|Bacteria,1UPUK@1239|Firmicutes,4HAJY@91061|Bacilli,3FB7M@33958|Lactobacillaceae 91061|Bacilli U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family tcyP - - ko:K06956 - - - - ko00000 - - - SDF CAFIFDFH_01751 353496.LBU_0390 6.71e-152 429.0 COG3548@1|root,COG3548@2|Bacteria,1VNI3@1239|Firmicutes,4HSHZ@91061|Bacilli,3F5J9@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) ybbB - - - - - - - - - - - DUF1211 CAFIFDFH_01752 353496.LBU_0391 2.61e-288 790.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F41R@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_2 - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr CAFIFDFH_01753 405566.lhv_1978 1.63e-94 280.0 COG1715@1|root,COG1715@2|Bacteria,1V7W8@1239|Firmicutes,4HHU7@91061|Bacilli,3F4T4@33958|Lactobacillaceae 91061|Bacilli L restriction endonuclease - - - ko:K07448 - - - - ko00000,ko02048 - - - Mrr_N,Mrr_cat CAFIFDFH_01754 334390.LAF_1160 4e-84 252.0 COG3338@1|root,COG3338@2|Bacteria,1V16J@1239|Firmicutes,4HA62@91061|Bacilli,3F60I@33958|Lactobacillaceae 91061|Bacilli P Eukaryotic-type carbonic anhydrase - - 4.2.1.1 ko:K01674 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Carb_anhydrase CAFIFDFH_01755 334390.LAF_1161 4.94e-241 682.0 COG0458@1|root,COG0458@2|Bacteria,1VRNP@1239|Firmicutes,4HTJU@91061|Bacilli,3FC3W@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3 CAFIFDFH_01756 405566.lhv_1974 1.33e-212 589.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HAYI@91061|Bacilli,3FB5V@33958|Lactobacillaceae 91061|Bacilli L COG2826 Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve CAFIFDFH_01757 326425.lhe_1815 9.33e-119 340.0 COG1309@1|root,COG1309@2|Bacteria,1U689@1239|Firmicutes,4IFZ0@91061|Bacilli,3F7AB@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator - - - - - - - - - - - - TetR_N CAFIFDFH_01758 326425.lhe_1816 1.33e-275 753.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,3F3X2@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N CAFIFDFH_01759 326425.lhe_1817 7.73e-79 234.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,3F6HC@33958|Lactobacillaceae 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS CAFIFDFH_01760 326425.lhe_1818 0.0 896.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,3F46Q@33958|Lactobacillaceae 91061|Bacilli F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C CAFIFDFH_01761 326425.lhe_1819 0.0 914.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,3F4SK@33958|Lactobacillaceae 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CAFIFDFH_01762 326425.lhe_1820 5.28e-53 166.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli,3FCDM@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L31 rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 CAFIFDFH_01763 326425.lhe_1821 1.46e-199 552.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,3F5C1@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase yhaX - - - - - - - - - - - Hydrolase_3 CAFIFDFH_01764 326425.lhe_1738 0.0 1689.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HBQJ@91061|Bacilli,3F4E0@33958|Lactobacillaceae 91061|Bacilli P COG0474 Cation transport ATPase mgtA - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 CAFIFDFH_01765 405566.lhv_0361 1.32e-34 120.0 2DS5S@1|root,33ENY@2|Bacteria,1VKTU@1239|Firmicutes,4HSXX@91061|Bacilli,3F6MW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01766 1033837.WANG_0042 2.98e-185 516.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,3F4K2@33958|Lactobacillaceae 91061|Bacilli U sugar transport - - - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport CAFIFDFH_01767 405566.lhv_0363 0.0 909.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F49B@33958|Lactobacillaceae 91061|Bacilli E Peptidase C1-like family pepC - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 CAFIFDFH_01768 405566.lhv_0277 9.13e-245 673.0 2DKJ8@1|root,309P7@2|Bacteria,1U5FB@1239|Firmicutes,4IF6X@91061|Bacilli,3F5UP@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP CAFIFDFH_01769 326425.lhe_1823 3.12e-208 577.0 29NJD@1|root,309H9@2|Bacteria,1U53C@1239|Firmicutes,4IEUN@91061|Bacilli,3F4BP@33958|Lactobacillaceae 91061|Bacilli S Bacteriocin helveticin-J - - - - - - - - - - - - Helveticin_J CAFIFDFH_01770 326425.lhe_1823 1.98e-18 82.4 29NJD@1|root,309H9@2|Bacteria,1U53C@1239|Firmicutes,4IEUN@91061|Bacilli,3F4BP@33958|Lactobacillaceae 91061|Bacilli S Bacteriocin helveticin-J - - - - - - - - - - - - Helveticin_J CAFIFDFH_01771 405566.lhv_0273 9.89e-206 569.0 2DI1S@1|root,301QZ@2|Bacteria,1U5TY@1239|Firmicutes,4IFHX@91061|Bacilli,3F6I2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - HTH_3 CAFIFDFH_01772 1423767.BALU01000001_gene1438 4.74e-29 112.0 COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,3F4M8@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 CAFIFDFH_01773 748671.LCRIS_00250 1.35e-106 326.0 COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,3F4M8@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 CAFIFDFH_01774 1423748.BALB01000010_gene1069 5.5e-31 119.0 COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,3F4M8@33958|Lactobacillaceae 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DUF772 CAFIFDFH_01775 405566.lhv_0268 7.67e-85 261.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 CAFIFDFH_01776 525365.HMPREF0548_2137 1.2e-31 116.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HF5U@91061|Bacilli,3FCCC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC CAFIFDFH_01777 326425.lhe_1692 1.19e-233 642.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HV6B@91061|Bacilli,3F4U8@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CAFIFDFH_01778 326425.lhe_1691 3.33e-162 455.0 COG2188@1|root,COG2188@2|Bacteria,1TVMZ@1239|Firmicutes,4H9TD@91061|Bacilli,3F66Q@33958|Lactobacillaceae 91061|Bacilli K UTRA frlR1 - - ko:K03710,ko:K10711 - - - - ko00000,ko03000 - - - GntR,UTRA CAFIFDFH_01779 1262915.BN574_00204 5.42e-12 67.8 28N73@1|root,2ZBBV@2|Bacteria,1UYD3@1239|Firmicutes 1239|Firmicutes S Toxin ToxN, type III toxin-antitoxin system - - - - - - - - - - - - ToxN_toxin CAFIFDFH_01780 326425.lhe_1690 2.01e-40 143.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli,3F4GS@33958|Lactobacillaceae 91061|Bacilli C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate bbsF_1 - 2.8.3.19 ko:K18702 - - - - ko00000,ko01000 - - - CoA_transf_3 CAFIFDFH_01781 326425.lhe_1690 2.17e-80 248.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli,3F4GS@33958|Lactobacillaceae 91061|Bacilli C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate bbsF_1 - 2.8.3.19 ko:K18702 - - - - ko00000,ko01000 - - - CoA_transf_3 CAFIFDFH_01782 326425.lhe_1690 1.26e-98 296.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli,3F4GS@33958|Lactobacillaceae 91061|Bacilli C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate bbsF_1 - 2.8.3.19 ko:K18702 - - - - ko00000,ko01000 - - - CoA_transf_3 CAFIFDFH_01783 891391.LAC30SC_01955 1.01e-138 405.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli,3F4GS@33958|Lactobacillaceae 91061|Bacilli C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate frc - 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 CAFIFDFH_01784 525365.HMPREF0548_2147 5.99e-70 226.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family spxB - 1.2.3.3,1.2.5.1,2.2.1.6,4.1.1.8 ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00207,R00226,R01908,R03050,R03145,R04672,R04673,R08648 RC00027,RC00106,RC00620,RC00860,RC01192,RC02744,RC02745,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CAFIFDFH_01785 525365.HMPREF0548_2147 4.92e-185 528.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family spxB - 1.2.3.3,1.2.5.1,2.2.1.6,4.1.1.8 ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00207,R00226,R01908,R03050,R03145,R04672,R04673,R08648 RC00027,RC00106,RC00620,RC00860,RC01192,RC02744,RC02745,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CAFIFDFH_01786 525365.HMPREF0548_2147 1.78e-17 80.9 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family spxB - 1.2.3.3,1.2.5.1,2.2.1.6,4.1.1.8 ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00207,R00226,R01908,R03050,R03145,R04672,R04673,R08648 RC00027,RC00106,RC00620,RC00860,RC01192,RC02744,RC02745,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CAFIFDFH_01787 326425.lhe_1687 0.0 1177.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,3F3QI@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn CAFIFDFH_01788 326425.lhe_1686 4.32e-148 417.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,3F40G@33958|Lactobacillaceae 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N CAFIFDFH_01789 405566.lhv_0417 1.11e-101 295.0 COG3279@1|root,COG3279@2|Bacteria,1VBF7@1239|Firmicutes,4IPQI@91061|Bacilli,3F7K4@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR CAFIFDFH_01790 326425.lhe_1684 1.53e-162 456.0 COG4758@1|root,COG4758@2|Bacteria,1V7WJ@1239|Firmicutes,4HR21@91061|Bacilli,3F6JJ@33958|Lactobacillaceae 91061|Bacilli S membrane - - - - - - - - - - - - DUF2154 CAFIFDFH_01791 1423748.BALB01000002_gene229 4.09e-117 342.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli,3F4JE@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family scrR - - ko:K02529,ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 CAFIFDFH_01792 1423748.BALB01000002_gene229 2.98e-29 112.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli,3F4JE@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family scrR - - ko:K02529,ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 CAFIFDFH_01793 891391.LAC30SC_01990 1.52e-131 390.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system scrA - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC CAFIFDFH_01794 326425.lhe_1681 6.11e-59 182.0 2DN64@1|root,32VRU@2|Bacteria,1UPY3@1239|Firmicutes,4IVD5@91061|Bacilli,3FC0U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01795 326425.lhe_1679 1.18e-114 329.0 2CHFM@1|root,301I5@2|Bacteria,1U5M7@1239|Firmicutes,4IFC0@91061|Bacilli,3F66G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01796 326425.lhe_1674 9.06e-60 184.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,3F7CZ@33958|Lactobacillaceae 91061|Bacilli O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 CAFIFDFH_01797 326425.lhe_1673 0.0 1013.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,3F3MM@33958|Lactobacillaceae 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 CAFIFDFH_01798 326425.lhe_1672 0.0 1692.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,3F4A5@33958|Lactobacillaceae 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V CAFIFDFH_01799 326425.lhe_1671 2.41e-116 352.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,3F3PK@33958|Lactobacillaceae 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C CAFIFDFH_01800 326425.lhe_1671 1.6e-304 839.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,3F3PK@33958|Lactobacillaceae 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C CAFIFDFH_01801 326425.lhe_1670 2.53e-133 378.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,3F42W@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N CAFIFDFH_01802 326425.lhe_1669 5.3e-240 660.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,3F47S@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N CAFIFDFH_01803 326425.lhe_1668 6.55e-82 244.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,3F7EY@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC CAFIFDFH_01804 326425.lhe_1667 0.0 996.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,3F48G@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N CAFIFDFH_01805 326425.lhe_1666 2.47e-274 749.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,3F44N@33958|Lactobacillaceae 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH CAFIFDFH_01806 326425.lhe_1665 1.63e-233 642.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F4FC@33958|Lactobacillaceae 91061|Bacilli S DHHA1 domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 CAFIFDFH_01807 326425.lhe_1664 3.67e-316 862.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,3F4FQ@33958|Lactobacillaceae 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C CAFIFDFH_01808 326425.lhe_1663 0.0 1753.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,3F3QS@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD CAFIFDFH_01809 1033837.WANG_0122 5.32e-57 176.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,3F7EG@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 CAFIFDFH_01810 326425.lhe_1661 6.59e-96 279.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,3F6NI@33958|Lactobacillaceae 91061|Bacilli J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX CAFIFDFH_01811 326425.lhe_1660 6.82e-66 200.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,3F6X3@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 CAFIFDFH_01812 326425.lhe_1659 0.0 1353.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,3F4DX@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr CAFIFDFH_01813 326425.lhe_0390 3.7e-99 290.0 29V33@1|root,30GGE@2|Bacteria,1UFZH@1239|Firmicutes,4IF1H@91061|Bacilli,3F5BQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01814 326425.lhe_0391 4.91e-62 191.0 2BZTJ@1|root,30A2T@2|Bacteria,1U644@1239|Firmicutes,4IFTP@91061|Bacilli,3F6ZQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01815 326425.lhe_0393 7.86e-134 382.0 29DQI@1|root,300NC@2|Bacteria,1U55V@1239|Firmicutes,4IEX6@91061|Bacilli,3F4UQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01816 326425.lhe_0394 0.0 961.0 2EZVI@1|root,33T01@2|Bacteria,1V7RP@1239|Firmicutes,4IEWB@91061|Bacilli,3F4QD@33958|Lactobacillaceae 91061|Bacilli S O-antigen ligase like membrane protein - - - - - - - - - - - - O-antigen_lig CAFIFDFH_01817 1423748.BALB01000044_gene2050 1.07e-49 159.0 2DKPT@1|root,30A91@2|Bacteria,1U6CF@1239|Firmicutes,4IG44@91061|Bacilli,3F7KP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF2187 CAFIFDFH_01818 326425.lhe_0396 1.2e-122 350.0 COG0194@1|root,COG0194@2|Bacteria,1VGNR@1239|Firmicutes,4IRT6@91061|Bacilli,3FBPU@33958|Lactobacillaceae 91061|Bacilli F Guanylate kinase homologues. gmk2 - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin CAFIFDFH_01819 326425.lhe_0397 7.91e-117 335.0 COG0791@1|root,COG0791@2|Bacteria,1V5H7@1239|Firmicutes,4IEXC@91061|Bacilli,3F4VI@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 CAFIFDFH_01820 525365.HMPREF0548_1594 2.54e-38 139.0 COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,4HF7F@91061|Bacilli,3F57U@33958|Lactobacillaceae 91061|Bacilli S Archaea bacterial proteins of unknown function - - - ko:K06921 - - - - ko00000 - - - ATPase_2,DUF234 CAFIFDFH_01821 326425.lhe_0753 0.0 1409.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase CAFIFDFH_01822 326425.lhe_0754 4.52e-140 396.0 COG4767@1|root,COG4767@2|Bacteria,1VK3A@1239|Firmicutes,4HPCD@91061|Bacilli,3F5EN@33958|Lactobacillaceae 91061|Bacilli V VanZ like family vanZ - - - - - - - - - - - VanZ CAFIFDFH_01823 326425.lhe_0755 0.0 903.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,3F3XK@33958|Lactobacillaceae 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI CAFIFDFH_01824 1423748.BALB01000001_gene109 2.92e-38 138.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 CAFIFDFH_01825 1423748.BALB01000001_gene109 1.16e-91 280.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 CAFIFDFH_01826 1423748.BALB01000001_gene109 1.02e-17 82.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 CAFIFDFH_01827 326425.lhe_0538 1.34e-195 542.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,3F43Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase CAFIFDFH_01828 326425.lhe_0537 0.0 971.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase CAFIFDFH_01829 326425.lhe_0536 5.95e-263 720.0 COG0438@1|root,COG0438@2|Bacteria,1UHSF@1239|Firmicutes,4HB04@91061|Bacilli,3F428@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 CAFIFDFH_01830 326425.lhe_0535 2.05e-173 483.0 COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,4HH6B@91061|Bacilli,3F4WB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid tagA - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB CAFIFDFH_01831 326425.lhe_1569 1.11e-67 207.0 COG1695@1|root,COG1695@2|Bacteria,1V6TJ@1239|Firmicutes,4HKXY@91061|Bacilli,3F70A@33958|Lactobacillaceae 91061|Bacilli K Virulence activator alpha C-term padR - - - - - - - - - - - PadR,Vir_act_alpha_C CAFIFDFH_01832 326425.lhe_1568 5.94e-133 375.0 COG3479@1|root,COG3479@2|Bacteria,1UY0X@1239|Firmicutes,4HAN3@91061|Bacilli,3F4P4@33958|Lactobacillaceae 91061|Bacilli Q Phenolic acid decarboxylase padC - - ko:K13727 - - - - ko00000,ko01000 - - - PA_decarbox CAFIFDFH_01833 326425.lhe_1567 3.17e-141 399.0 COG5464@1|root,COG5464@2|Bacteria,1V1A7@1239|Firmicutes,4HG0B@91061|Bacilli,3F655@33958|Lactobacillaceae 91061|Bacilli S PD-(D/E)XK nuclease family transposase - - - - - - - - - - - - PDDEXK_2 CAFIFDFH_01835 405566.lhv_1699 0.0 1117.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,3F4DE@33958|Lactobacillaceae 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d CAFIFDFH_01836 326425.lhe_1565 5.16e-218 601.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,3F4EF@33958|Lactobacillaceae 91061|Bacilli G Fructose-1,6-bisphosphate aldolase, class II fba - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase CAFIFDFH_01837 326425.lhe_1564 4.18e-118 338.0 COG0494@1|root,COG0494@2|Bacteria,1V55F@1239|Firmicutes,4HJEI@91061|Bacilli,3F50F@33958|Lactobacillaceae 91061|Bacilli L NUDIX domain - - - - - - - - - - - - NUDIX CAFIFDFH_01838 326425.lhe_1563 3.27e-53 167.0 2ETIJ@1|root,33M2D@2|Bacteria,1W6M0@1239|Firmicutes,4IFY8@91061|Bacilli,3F79G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01839 326425.lhe_1562 1.5e-42 139.0 29QS7@1|root,30BS2@2|Bacteria,1U8JH@1239|Firmicutes,4IIHG@91061|Bacilli,3FB1X@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01840 326425.lhe_1587 0.0 1020.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,3F404@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C CAFIFDFH_01841 326425.lhe_1588 0.0 1679.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,3F46M@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 CAFIFDFH_01842 326425.lhe_1589 4.15e-153 430.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,3F5CM@33958|Lactobacillaceae 91061|Bacilli I Acid phosphatase homologues yodM - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 CAFIFDFH_01843 1423748.BALB01000034_gene1968 6.71e-55 179.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,3F4GC@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt CAFIFDFH_01844 1423748.BALB01000003_gene458 2.64e-212 593.0 29NRF@1|root,30B3D@2|Bacteria,1U7GM@1239|Firmicutes,4IHCZ@91061|Bacilli,3F9MT@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP CAFIFDFH_01845 1423748.BALB01000003_gene458 1.14e-29 116.0 29NRF@1|root,30B3D@2|Bacteria,1U7GM@1239|Firmicutes,4IHCZ@91061|Bacilli,3F9MT@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP CAFIFDFH_01846 405566.lhv_1499 3.11e-249 682.0 COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,4HADZ@91061|Bacilli,3F48R@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of alpha and beta anomers of maltose galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim CAFIFDFH_01847 405566.lhv_1500 0.0 986.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli,3F4D8@33958|Lactobacillaceae 91061|Bacilli G UDP-glucose--hexose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf CAFIFDFH_01848 405566.lhv_1501 1.15e-282 772.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli,3F3Q9@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg CAFIFDFH_01850 748671.LCRIS_01642 3.42e-24 99.4 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,3F42G@33958|Lactobacillaceae 91061|Bacilli K rpiR family - - - - - - - - - - - - HTH_6,SIS CAFIFDFH_01851 326425.lhe_1905 5.47e-151 424.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,3F488@33958|Lactobacillaceae 91061|Bacilli F deoxynucleoside kinase dak - 2.7.1.76 ko:K10353 ko00230,ko01100,map00230,map01100 - R02089 RC00002,RC00017 ko00000,ko00001,ko01000 - - - dNK CAFIFDFH_01852 326425.lhe_1906 4.37e-156 438.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,3F488@33958|Lactobacillaceae 91061|Bacilli F deoxynucleoside kinase dgk2 - 2.7.1.76 ko:K10353 ko00230,ko01100,map00230,map01100 - R02089 RC00002,RC00017 ko00000,ko00001,ko01000 - - - dNK CAFIFDFH_01853 326425.lhe_1907 9.06e-189 524.0 COG0561@1|root,COG0561@2|Bacteria,1TSGF@1239|Firmicutes,4HHWU@91061|Bacilli,3F57T@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 CAFIFDFH_01854 405566.lhv_2082 2.96e-279 766.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,3F44D@33958|Lactobacillaceae 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease CAFIFDFH_01855 748671.LCRIS_01995 5.03e-219 609.0 COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,4HCSJ@91061|Bacilli,3F51K@33958|Lactobacillaceae 91061|Bacilli S cog cog1373 - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CAFIFDFH_01856 405566.lhv_1189 8.57e-314 857.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans CAFIFDFH_01857 326425.lhe_1080 2.03e-73 220.0 2BN3Q@1|root,32GQJ@2|Bacteria,1U7WD@1239|Firmicutes,4IHTS@91061|Bacilli,3FA99@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01858 1423748.BALB01000033_gene1956 2.73e-114 333.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CAFIFDFH_01859 525365.HMPREF0548_1061 4.93e-68 217.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CAFIFDFH_01860 1423748.BALB01000033_gene1959 8.9e-51 160.0 29PA0@1|root,30A85@2|Bacteria,1U6BF@1239|Firmicutes,4IG31@91061|Bacilli,3F7IE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01861 326425.lhe_1077 3.67e-131 372.0 COG1988@1|root,COG1988@2|Bacteria,1TV5H@1239|Firmicutes,4ICPV@91061|Bacilli,3F689@33958|Lactobacillaceae 91061|Bacilli S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM CAFIFDFH_01862 326425.lhe_1075 1.34e-121 347.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,3F3K3@33958|Lactobacillaceae 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran CAFIFDFH_01864 405566.lhv_1541 1.61e-70 223.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,3FCFA@33958|Lactobacillaceae 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 CAFIFDFH_01865 326425.lhe_1383 1.55e-24 92.4 29PZS@1|root,30AY7@2|Bacteria,1U799@1239|Firmicutes,4IH45@91061|Bacilli,3F959@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01866 326425.lhe_1384 0.0 1164.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 CAFIFDFH_01868 1423748.BALB01000022_gene1690 1.38e-121 359.0 29V6Q@1|root,30GKE@2|Bacteria,1UG8H@1239|Firmicutes,4IF4J@91061|Bacilli,3F5M6@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP CAFIFDFH_01869 1423748.BALB01000022_gene1690 4.08e-69 222.0 29V6Q@1|root,30GKE@2|Bacteria,1UG8H@1239|Firmicutes,4IF4J@91061|Bacilli,3F5M6@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP CAFIFDFH_01870 405566.lhv_0672 2.02e-29 108.0 COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,4IR8Z@91061|Bacilli,3F6Q9@33958|Lactobacillaceae 91061|Bacilli L IS66 Orf2 like protein - - - ko:K07484 - - - - ko00000 - - - TnpB_IS66 CAFIFDFH_01871 353496.LBU_1508 2.68e-264 726.0 COG2271@1|root,COG2271@2|Bacteria,1TPJB@1239|Firmicutes,4HEY7@91061|Bacilli,3F4VX@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CAFIFDFH_01872 1423748.BALB01000003_gene430 6.71e-26 104.0 COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,3F3PU@33958|Lactobacillaceae 91061|Bacilli P aluminum resistance ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - - - - - - - - - - Met_gamma_lyase CAFIFDFH_01873 1423748.BALB01000003_gene430 2.46e-69 220.0 COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,3F3PU@33958|Lactobacillaceae 91061|Bacilli P aluminum resistance ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - - - - - - - - - - Met_gamma_lyase CAFIFDFH_01874 326425.lhe_1448 0.0 909.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,3F41A@33958|Lactobacillaceae 91061|Bacilli E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N CAFIFDFH_01875 326425.lhe_1447 1.39e-174 486.0 2ACE2@1|root,311ZJ@2|Bacteria,1U5CK@1239|Firmicutes,4IF3R@91061|Bacilli,3F5IZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF4767 CAFIFDFH_01876 405566.lhv_1556 1.85e-210 582.0 2ACE2@1|root,309I3@2|Bacteria,1U54Z@1239|Firmicutes,4IEW5@91061|Bacilli,3F4PW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01877 326425.lhe_1445 7.78e-203 565.0 2ACE2@1|root,309NT@2|Bacteria,1U5E7@1239|Firmicutes,4IF5H@91061|Bacilli,3F5PN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01878 326425.lhe_1264 1.54e-269 738.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,3F490@33958|Lactobacillaceae 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG CAFIFDFH_01879 326425.lhe_1265 0.0 1160.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,3F48C@33958|Lactobacillaceae 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 CAFIFDFH_01880 326425.lhe_1266 6.14e-115 333.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,3F4DY@33958|Lactobacillaceae 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE CAFIFDFH_01881 326425.lhe_1267 2.99e-247 679.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,3F3ST@33958|Lactobacillaceae 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg CAFIFDFH_01882 326425.lhe_1268 2.23e-232 639.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,3F3TG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase CAFIFDFH_01883 405566.lhv_1340 5.76e-212 585.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,3F3NX@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N CAFIFDFH_01884 326425.lhe_1270 1.37e-78 234.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,3F6WZ@33958|Lactobacillaceae 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA CAFIFDFH_01885 405566.lhv_1342 0.0 1536.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,3F3JV@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N CAFIFDFH_01886 326425.lhe_1272 1.32e-63 194.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,3F7ZK@33958|Lactobacillaceae 91061|Bacilli J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae CAFIFDFH_01887 405566.lhv_1344 2.64e-63 193.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,3F7E2@33958|Lactobacillaceae 91061|Bacilli K Protein of unknown function (DUF448) ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 CAFIFDFH_01888 326425.lhe_1274 3.24e-271 743.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,3F3KZ@33958|Lactobacillaceae 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 CAFIFDFH_01889 326425.lhe_1275 1.18e-108 313.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,3F6GZ@33958|Lactobacillaceae 91061|Bacilli J Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C CAFIFDFH_01890 326425.lhe_1276 0.0 2881.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,3F4AN@33958|Lactobacillaceae 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon CAFIFDFH_01891 326425.lhe_1277 0.0 1117.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,3F44A@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit CAFIFDFH_01892 326425.lhe_1278 1.57e-254 703.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,3F3TM@33958|Lactobacillaceae 91061|Bacilli M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 CAFIFDFH_01893 326425.lhe_1279 1.62e-189 526.0 COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,4IV81@91061|Bacilli,3F4AF@33958|Lactobacillaceae 91061|Bacilli I Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 CAFIFDFH_01894 326425.lhe_1280 1.91e-179 499.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,3F42M@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf CAFIFDFH_01895 326425.lhe_1281 8.57e-122 348.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,3F4X2@33958|Lactobacillaceae 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF CAFIFDFH_01896 326425.lhe_1282 5.02e-169 472.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,3F42J@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase CAFIFDFH_01897 326425.lhe_1283 1.84e-237 654.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,3F459@33958|Lactobacillaceae 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS CAFIFDFH_01898 326425.lhe_1284 2.21e-180 502.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,3F3M1@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 CAFIFDFH_01899 326425.lhe_1285 2.69e-256 701.0 COG2827@1|root,COG4123@1|root,COG2827@2|Bacteria,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,3F4C5@33958|Lactobacillaceae 91061|Bacilli L Methyltransferase small domain yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS CAFIFDFH_01900 326425.lhe_1286 2.26e-149 419.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,3F4QB@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase CAFIFDFH_01901 353496.LBU_1254 4.43e-294 801.0 COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,4HDKI@91061|Bacilli,3F3PA@33958|Lactobacillaceae 91061|Bacilli M cyclopropane-fatty-acyl-phospholipid synthase cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS CAFIFDFH_01902 326425.lhe_1288 0.0 1302.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F4CX@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N CAFIFDFH_01903 748671.LCRIS_01290 0.0 940.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran CAFIFDFH_01904 748671.LCRIS_01291 1.12e-152 445.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran CAFIFDFH_01905 748671.LCRIS_01291 7.19e-192 546.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran CAFIFDFH_01906 326425.lhe_0020 0.0 885.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,3F4MW@33958|Lactobacillaceae 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C CAFIFDFH_01907 326425.lhe_0019 9.88e-100 290.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,3F68P@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N CAFIFDFH_01908 326425.lhe_0018 0.0 1287.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,3F3TY@33958|Lactobacillaceae 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 CAFIFDFH_01909 326425.lhe_0017 1.54e-84 249.0 29DXA@1|root,300V7@2|Bacteria,1U59E@1239|Firmicutes,4IF0P@91061|Bacilli,3F59A@33958|Lactobacillaceae 91061|Bacilli S SLAP domain - - - - - - - - - - - - SLAP CAFIFDFH_01910 1033837.WANG_0315 0.0 1051.0 2FIUN@1|root,34AK2@2|Bacteria,1W1FZ@1239|Firmicutes,4HYXZ@91061|Bacilli,3F4QI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - SH3_8 CAFIFDFH_01911 1033837.WANG_0316 7.07e-106 305.0 28WWC@1|root,2ZIVN@2|Bacteria,1W4GP@1239|Firmicutes,4I0DB@91061|Bacilli,3F5SC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01912 326425.lhe_1046 1.49e-142 401.0 COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,3F3YI@33958|Lactobacillaceae 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR CAFIFDFH_01913 405566.lhv_2509 5.54e-88 258.0 2DYG7@1|root,349JS@2|Bacteria,1W0V5@1239|Firmicutes,4HYMX@91061|Bacilli,3FC0P@33958|Lactobacillaceae 91061|Bacilli S ASCH domain - - - - - - - - - - - - ASCH CAFIFDFH_01914 405566.lhv_1152 8.86e-214 590.0 COG1715@1|root,COG1715@2|Bacteria,1V7W8@1239|Firmicutes,4HHU7@91061|Bacilli,3F4T4@33958|Lactobacillaceae 91061|Bacilli L restriction endonuclease - - - ko:K07448 - - - - ko00000,ko02048 - - - Mrr_N,Mrr_cat CAFIFDFH_01915 405566.lhv_1153 1.88e-183 511.0 COG4889@1|root,COG4889@2|Bacteria,1UJIG@1239|Firmicutes,4ITGD@91061|Bacilli,3F5WY@33958|Lactobacillaceae 91061|Bacilli L helicase - - - - - - - - - - - - - CAFIFDFH_01916 1423767.BALU01000011_gene215 9.88e-87 265.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,3F4GC@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt CAFIFDFH_01917 326425.lhe_1591 0.0 912.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator mdr - - - - - - - - - - - MFS_1 CAFIFDFH_01918 326425.lhe_1592 3.04e-279 764.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,3F3T0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N CAFIFDFH_01921 326425.lhe_1595 2.49e-227 625.0 COG0803@1|root,COG0803@2|Bacteria,1V110@1239|Firmicutes,4HE71@91061|Bacilli,3FC74@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA CAFIFDFH_01924 326425.lhe_1739 3.29e-234 643.0 COG4639@1|root,COG4639@2|Bacteria,1TQKR@1239|Firmicutes,4HF9B@91061|Bacilli,3F51A@33958|Lactobacillaceae 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_33,Metallophos,RNA_lig_T4_1 CAFIFDFH_01925 326425.lhe_1740 2.41e-164 459.0 COG0588@1|root,COG0588@2|Bacteria,1V2UT@1239|Firmicutes,4HGRK@91061|Bacilli,3F443@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA1 - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 CAFIFDFH_01926 326425.lhe_1741 1.16e-31 110.0 29PJE@1|root,30AHJ@2|Bacteria,1U6P8@1239|Firmicutes,4IGG9@91061|Bacilli,3F88U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CAFIFDFH_01927 405566.lhv_0353 1.52e-208 577.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,3F4KJ@33958|Lactobacillaceae 91061|Bacilli P cation diffusion facilitator family transporter - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer CAFIFDFH_01928 326425.lhe_1743 8.07e-163 455.0 COG0406@1|root,COG0406@2|Bacteria,1TQF1@1239|Firmicutes,4I2XH@91061|Bacilli,3F4RY@33958|Lactobacillaceae 91061|Bacilli G Belongs to the phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 CAFIFDFH_01929 405566.lhv_0350 3.13e-173 484.0 COG0730@1|root,COG0730@2|Bacteria,1VR9G@1239|Firmicutes,4HV4W@91061|Bacilli,3F3TR@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE CAFIFDFH_01930 1423748.BALB01000002_gene293 2.01e-18 80.9 COG0546@1|root,COG0546@2|Bacteria,1UMZH@1239|Firmicutes,4IU43@91061|Bacilli,3FBY3@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 CAFIFDFH_01931 1423748.BALB01000002_gene293 1.53e-78 238.0 COG0546@1|root,COG0546@2|Bacteria,1UMZH@1239|Firmicutes,4IU43@91061|Bacilli,3FBY3@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 CAFIFDFH_01932 748671.LCRIS_00061 4.33e-103 299.0 2DPM9@1|root,332MQ@2|Bacteria,1VGFB@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - CAFIFDFH_01935 748671.LCRIS_00063 1.76e-109 315.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - CAFIFDFH_01936 326425.lhe_0271 4.71e-124 353.0 COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HGYP@91061|Bacilli,3FCDX@33958|Lactobacillaceae 91061|Bacilli M acetyltransferase (GNAT) family - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_4 CAFIFDFH_01937 326425.lhe_0272 6.37e-23 87.4 COG3682@1|root,COG3682@2|Bacteria,1U8JF@1239|Firmicutes,4IIHE@91061|Bacilli,3FB1V@33958|Lactobacillaceae 91061|Bacilli K Penicillinase repressor - - - - - - - - - - - - Penicillinase_R CAFIFDFH_01938 326425.lhe_0273 0.0 1283.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,3F4IX@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase copB - 3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54 ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5,3.A.3.6 - - E1-E2_ATPase,Hydrolase CAFIFDFH_01939 218140.BPSY_0287 4.96e-93 274.0 COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4D02G@85004|Bifidobacteriales 201174|Actinobacteria EGP Transmembrane secretion effector - - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1,MFS_3 CAFIFDFH_01940 1122149.BACN01000101_gene1967 2.01e-44 154.0 COG0477@1|root,COG2814@2|Bacteria,1TRZB@1239|Firmicutes,4HBXV@91061|Bacilli,3F5A0@33958|Lactobacillaceae 91061|Bacilli EGP Transmembrane secretion effector mdt(A) - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1,MFS_2,MFS_3 CAFIFDFH_01941 326425.lhe_1389 2.84e-150 422.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F5SD@33958|Lactobacillaceae 91061|Bacilli G phosphoglycerate mutase pgm1 - - - - - - - - - - - His_Phos_1 CAFIFDFH_01942 405566.lhv_0048 2.5e-263 721.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,3F4IU@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 CAFIFDFH_01943 326425.lhe_1387 1.83e-279 764.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,3F4JJ@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT_4 CAFIFDFH_01944 797515.HMPREF9103_01981 3.98e-39 132.0 COG2076@1|root,COG2076@2|Bacteria,1VEZX@1239|Firmicutes,4HKXB@91061|Bacilli,3F7D6@33958|Lactobacillaceae 91061|Bacilli U Multidrug resistance protein sugE - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res CAFIFDFH_01945 1423748.BALB01000009_gene1024 2.1e-53 174.0 COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,4HEX8@91061|Bacilli,3F5HS@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_5,DDE_Tnp_1 CAFIFDFH_01946 326425.lhe_0242 1.57e-170 475.0 COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,4HD1P@91061|Bacilli,3F4CH@33958|Lactobacillaceae 91061|Bacilli S glutamine amidotransferase cobQ - - ko:K07009 - - - - ko00000 - - - GATase_3 CAFIFDFH_01948 326425.lhe_0243 2.42e-195 541.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,3F3NA@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin CAFIFDFH_01949 1423767.BALU01000001_gene1512 1.67e-103 312.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,3F3WI@33958|Lactobacillaceae 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N CAFIFDFH_01950 1423748.BALB01000024_gene1758 3.04e-206 580.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,3F3WI@33958|Lactobacillaceae 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N CAFIFDFH_01951 405566.lhv_2006 7.79e-190 526.0 COG2365@1|root,COG2365@2|Bacteria,1W78R@1239|Firmicutes,4IEVA@91061|Bacilli,3F4QQ@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 CAFIFDFH_01952 1033837.WANG_1499 5.59e-30 116.0 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli,3F6CN@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 CAFIFDFH_01953 1033837.WANG_1286 6.84e-174 503.0 COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,4HC84@91061|Bacilli,3F48Q@33958|Lactobacillaceae 91061|Bacilli S Membrane protein involved in the export of O-antigen and teichoic acid - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C CAFIFDFH_01955 1005704.HMPREF9968_0009 3.21e-17 80.9 COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HCW0@91061|Bacilli,1WPSV@1303|Streptococcus oralis 91061|Bacilli S Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glycos_transf_2 CAFIFDFH_01957 405566.lhv_1507 0.0 1243.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,3F4S2@33958|Lactobacillaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family XK27_00340 - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,Metallophos CAFIFDFH_01958 405566.lhv_1508 5.45e-278 762.0 COG0477@1|root,COG2814@2|Bacteria,1TQM0@1239|Firmicutes,4HATA@91061|Bacilli,3F3SE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - ko:K08196 - - - - ko00000,ko02000 2.A.1.15 - - MFS_1,Sugar_tr ## 1845 queries scanned ## Total time (seconds): 1.5344161987304688 ## Rate: 1202.41 q/s