LOCUS       c00057_gnlPro..        16017 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CAFIFDFH_161.
ACCESSION   c00057_gnlPro..
VERSION     c00057_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 10:45:31
            Original ID  :: gnl|Prokka|CAFIFDFH_161
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16017
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16017
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2739:6017]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2740..6017
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..16017
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16017
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(115..720)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_1"
                     /sec_met_domain="LysR_substrate (E-value: 1.1e-18,
                     bitscore: 58.1, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEDVVIKDFILLAKKVY"
     CDS             complement(723..884)
                     /locus_tag="ctg57_2"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLNVVVSGINVVISLLIMFNKYQIRKDKKQISDE
                     GHAPLDEN"
     CDS             complement(900..2066)
                     /locus_tag="ctg57_3"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIEYAFLKDSDLTTDSNFMPRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQK
                     IPVANLAPFSEKFYRHYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHIDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMAAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLSCMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             complement(2187..2723)
                     /locus_tag="ctg57_4"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNKGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             complement(2740..3081)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_5"
                     /sec_met_domain="AA_kinase (E-value: 5.2e-19, bitscore:
                     59.4, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGVAGVIDKDFSAAKLAEDIQADELVILTTVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFVAGSMKPKIEAVIDFVEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             complement(3393..3674)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_6"
                     /sec_met_domain="AA_kinase (E-value: 1.6e-11, bitscore:
                     34.9, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVVLGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNLAMPLDTVVSMTQGSISAIGCKRP"
     CDS             complement(3869..4477)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_7"
                     /sec_met_domain="OTCace (E-value: 6.3e-37, bitscore: 117.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 1.4e-24, bitscore:
                     77.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDDIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPTQMLADFMTIKEKFGHLKVLILAYVGDGRDNVADSLLVAGSMLGV
                     NVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIEQGVKGANIIYTDVWVSMGEND
                     WSERIKLLKPYTVTMNMMYMTGTPDDQLIFMHCLPAFHD"
     CDS             complement(4725..5279)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_8"
                     /sec_met_domain="Amidinotransf (E-value: 1.9e-49, bitscore:
                     159.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLAIGISQITSAAAITDLAHSLFGHSSYDTILAIKIPHNHAMMH
                     LDTVFTMINYDQCTVHPFILDKSGKIDIYVLEQDDHGEIKITPETDLIKVLKNYLHLSE
                     IDLIPTGGGDAIAAPREQWNNGSNTLAIAPGEVVTYDRNYVSNDLLRKHGILVHEIHSS
                     ELSRGRGGPRCMSCPLVREDL"
     CDS             complement(5227..5646)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_9"
                     /sec_met_domain="Amidinotransf (E-value: 5.5e-25, bitscore:
                     78.8, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLIAMPVNEMVKQIIAGIRKNEIQNATPSLADLAEDPDYSFYS
                     FYLDPMLNVYFTRDQQAVIGNGMTINRMTSRARRRESLFMETVLKHHPDFKNANIPIWR
                     DRYTHGRLEGGDELILNNHVFSNRYFSNNFRCRNH"
     CDS             complement(5778..6017)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_10"
                     /sec_met_domain="Amidinotransf (E-value: 4.1e-11, bitscore:
                     33.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LINNYCKRIHNFELGDAIMTDLIHVYSEIGKLETVMLHRPGRELE
                     NLSPDILNRMLIDDIPYLKIAQKEHDYFAHTLEK"
     CDS             complement(6037..6891)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     73.6; E-value: 3.1e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg57_11"
                     /sec_met_domain="LysR_substrate (E-value: 6.5e-31,
                     bitscore: 98.0, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.3e-23, bitscore: 73.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAEEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKLKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKHSNWITHLQLVWRKDQKVTPLMKRIIDS
                     LSR"
     CDS             7020..9293
                     /locus_tag="ctg57_12"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEAPEPEYNFFKEFLSKLWNLSA
                     WVLEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRWVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSDLSDLPDKDVLALAGSATDKRNAGII
                     DIAIDEYLKENNIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYFFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTYITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFFSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(9361..9825)
                     /locus_tag="ctg57_13"
                     /transl_table=11
                     /translation="MLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTRNATVYNRHGVKV
                     GHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVVNRIKKHSFVYDE
                     NGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTVTNY"
     CDS             10000..10245
                     /locus_tag="ctg57_14"
                     /transl_table=11
                     /translation="MILTWNIIRRTIEVLWIINIAFAVWTVFRSRRSVVATWAWMLVLT
                     VLPGIGFILYLFFGRQLSHDEIFAIQEEQKRYKDII"
     CDS             10260..11486
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_15"
                     /sec_met_domain="PLDc_2 (E-value: 3.4e-27, bitscore: 85.7,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKEHDLLPEKEHLPRVRMLSELNLNNDDAILTFDNQVKVFISGP
                     ELFDQMITDIKNAKKSVSLEFYTFYSNQLGHLVLKALEEAAANGAKVRVIYDTSGSRGT
                     KPSFFDHLRELGGEAQPFISTSKKHWFTTPRLNYHLHRKLVIIDHHIGYIGGFNIGDQY
                     VNKSPKFGHWRDTHLRVIGQSPILMEVRFAMDWNTSIRRTNLPKFELKELKPFTVNRKD
                     INDNKNVAMQLFPQDLIINITASDEAEGIIAGAKKYIYIQTPYLIPEESILEALIIAAN
                     SGIDVRIMVPCMPDHPFVYRATEYYAKYLVAHGVKVYKYNDGFIHAKTMVSGSNISSVG
                     SANQDFRSYTLNFEVNSFNYNPALTQELKKIFEKDLDKCTLLTNDYFAQQSLWLKFKQY
                     FSRLLSPIF"
     CDS             11614..12408
                     /locus_tag="ctg57_16"
                     /transl_table=11
                     /translation="LANRVKIGVLNLMHDKLDTQQRFARVLPDADLTFFYPRMHYQNRP
                     VPPEVAKTSQPLDLNQIKEFDGFIITGAPLDHLDFDQVTYIEEVRCLLQLLDKYKLQQL
                     YFCWGAMAALDYFYNIQKRILSKKIFGVFPHLIIEPHPLLNGLSKGFIAPHARYAEMDK
                     TQIMQDPRLTINSVDDNGHLFMVSSLEKPEQNFIFSHIEYGRKGLKKEYEREIAAHPER
                     HYKKPENYSLSNLLFQWKDTQKTFFNNWLTQVKKSKLVLLDK"
     CDS             12424..13353
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_17"
                     /sec_met_domain="PALP (E-value: 6.4e-69, bitscore: 223.2,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIYNSVTELIGNTPLLKLNRVVPDDAADVYVKLEFENPAGSIK
                     DRIALAMIEKAEREGNLKPGGTIVEPTSGNTGIGLAMVAAAKDYHIIIVMPETMSVERR
                     KLMKGYGAELILTPGADGMKGSIAKAEELVKEKGYFMPMQFENTENPNIHELTTGPEII
                     AAMNGIGKSVDAFVAGVGTGGTLSGIGHALRRENPSTKIFALEPTESPLLKDGKTGKHG
                     IQGIAAGFIPKNLDKDIYDDIITVSTDEAMATAREVAKNEGFLPGISAGANIHGAIEIA
                     KKLGKGHAVVTVVPDGGDRYLSTALFNA"
     CDS             complement(13497..14042)
                     /locus_tag="ctg57_18"
                     /transl_table=11
                     /translation="MEVFLLMAIDFSKYIASVKDFPNKGIVFRDITPILQDGELYRIAT
                     HELAEYAKSRKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEY
                     GSNSLEMHKDAIKPGQRVVLCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLKG
                     REKLPDVDIYSLVQYHGA"
ORIGIN
        1 actacattct atcaaacagg tccgaatgga ctttttattt tttatcaagt gttcaattta
       61 attttacaat cagcgcattt ttatttttac agtattttgc tgttccaaga tagattaata
      121 tactttttta gctaacaaaa taaaatcttt aattactaca tcttcattgg tataaaaagc
      181 tgcaatcttt tgccacattt gttgtccatt agacaataaa aacaatcgtt gtaaagtatc
      241 attactaatt aaactggcgg ttgcttcatt cattaaaaaa tatcctgatc cagaagctac
      301 taacaatgct gcctcttcta cggaatttga agcaatgaat gggcttctaa tctgataaat
      361 atctttaaat aaatggagtt ctgcagcctc ttcttcaggc ttagctacaa taaaacaggt
      421 taaatcagct agatcatctt tattgatcat ctgaacaccg ctaggataac tacccttttg
      481 caaaatagcc attactgctt cctgacctaa gatttctttc ttaaaatcga gctgatcatc
      541 gcgcaaatca ctaatcgcta aatcaacttc atttttggct aatttatcaa aagcttcatc
      601 gtgtcccatt ccaattaatt caatttctac atcagaatgt ttttgcttaa attggtctac
      661 aattcgatct aattgtcttc taccaagttg gttaaagtat gctattctca attttttcat
      721 agttaatttt catccaatgg ggcatgacct tcatctgata tttgtttttt atcttttcta
      781 atttgatatt tgttgaacat aatcaatagc gaaataacca catttattcc actaactacc
      841 acgtttaaaa attttagtaa tctaactttc ttttgcttac tcattttgga taccttcttc
      901 taaaaataat cataaaatga gactttacct tttacaaagt ccaacttttt aattctataa
      961 tctgtgatca aaccaagttt aattgcggat tccatagtta aacgtcctaa taagatttga
     1021 gtccatgttg taattggacc agagaaatca actagttcat cttcttttcg ttcacactta
     1081 acttggtgat cataattagt taattgccaa acgccgatat tccatggaca ctgatcatca
     1141 taattaactt cgatgttaaa agtaccctct tgcaatgggc gcatgcatga caagactttt
     1201 tggaaatcaa taattctact catcatatat ggatgaagtt gaatatccaa ttcattttgc
     1261 tctggaaaaa gttcagccaa taaagacttc tcaggcaatg tcatacaaaa ctctttaatt
     1321 gaccctatat gagctgccat aaagcctaat atgcttaata atccttgagg cgtaattgaa
     1381 tataattcat cagccataaa acagttatca attatgcgat aaatcaagta gctcatcggc
     1441 cgaccagctt catcgaagta aacagcaatc tctcgatgat gataataatc atctaatcta
     1501 ttccaccacc aagcttctct gatgatcgta tttctttcat cgtcaatatg caactgacgt
     1561 tcatataatt gaatcacacc attttgaaca atcaaatcat tccattttcc acgaattatc
     1621 ttacctttgc gtggtaatct gaaagaagca agtgcagctc ccgaaaagcg atattctttt
     1681 tggtaaatac tattgctaaa accataatga cgataaaatt tttctgaaaa tggagctaga
     1741 ttggcaactg ggattttttg atcatgcaaa tcaaaaagaa tttctttcat taatttagat
     1801 atatgtccac gtcctctgta ttcaggatat gatgccacat aaccaatacc tgccagtgga
     1861 acatgatgac caaatatctc agctttaaac ttattgacca tcatataact ggtcaatttt
     1921 tcttgatcaa aatatccata tccatcacta tgatcatatc ggggcataaa gttactatct
     1981 gtagtcaaat cagaatcttt taaaaaagca tattcaatca atgaagcaat ttgttttaaa
     2041 ttgtcttggt ttttctttaa tttcatagtt ttccttacaa tatatattca taactttact
     2101 tatattttag aacattttat gtatttttcg ttagcttttt ttaagattta aatgaaaaaa
     2161 cgggatgatt agcctcccat cccgttttaa ttatttacat acttcgcata taaactagaa
     2221 atgtatcttt gcatctcttc tactgagtgt cgccgtgatc gagcacactc tttagcaggg
     2281 cgattgcata aatagcagcg gcgactagag tattcaagct cttggcgtga aagtgcagtt
     2341 ttccctttaa ttaatacatc ggcatcaaat aatcgtccta ttttattatt ttcttcaaat
     2401 aaaattgtag ataatttaac tactttgcta gattctcgca aaacatagaa attttcacat
     2461 ccagcatcat tatttaatgc ttttactaat ttatagtcat atcccttatt ctgccatatt
     2521 tcttctaatt gtttaattcc gtaatcaaat aatttgatta aatatcgatt atttttaatt
     2581 ggccccggga tatttaagtt tatatcaacc aaagtcgcat caggatactt tttaaaaata
     2641 gcttgctgca aagctacacg ataatctttt ccagctaata cctgagcaat attttgcgga
     2701 tttccttctt gaaaaatgtt catttatatc tcaccgcagt taattataaa caattgtacc
     2761 tactccatca tcaagtttac ttgcatttct taaagaagta ataattgcag tctttcctgt
     2821 tttctctacg aaatcaatga cagcttcaat ttttggcttc atgctgcctg caacaaattg
     2881 gccagcttct agatacttct ttaattgatc aatctttatt tttccaatag gagcttgatc
     2941 aggttgatta tagttcacgt aggcattgtc aacggtagtt agaataacta attcatctgc
     3001 ttgaatatct tcagctagtt ttgcggcact gaagtcttta tcaattactc ctgctacgcc
     3061 ttgcaaacta tcgtctttca ctacaacagg aattccacca cctccggcag caataggaac
     3121 aaacttgctc tttagtaaag tgtcaatgcc tggtgcatta ataattttaa cgagctttgg
     3181 agaagaaact acttgacgat agcctcgacc tgtatcttgc ttataagtat attcaggatg
     3241 atagattttt tacctctgca tttcgttaaa tgtataaaat gggccaattg gtttagttgg
     3301 attcttaaaa gttggatcat tcgcattaac tattatctga gtaattaaag caacagcttg
     3361 atgtggataa tttgtatgtt taaattgatc gtctaaggcc ttttgcatcc aatagccgat
     3421 atactgcctt gagtcattga tactactgta tcaagcggca tagcgagatt atctttactt
     3481 gaacctttgt attgttgcaa aagcaaatta ccaacctgcg ggccattacc atgaacaatc
     3541 gctacctgat caccattttc aatcatttta gcaacaacct tcattgtctt tttaacctgc
     3601 ttttcttggg cagctgcact attatcacct gcttcaatag cattgccacc caaaaccaca
     3661 actattcttt tcatctttat ttacttcctt catcaactga cggaataaac aaattgccca
     3721 aagtagcggc cattattgct ttgatagaat gcaatctatt ttccgcttca gtaaattgcc
     3781 aagcgtattg agagttaaag acttcatctg taacttccac ttcacttaga ccatattttt
     3841 cataaatttc tttgccaact ttagcagttc aatcatgaaa cgcaggcaaa cagtgcataa
     3901 agattagttg atcatccggg gtgcctgtca tatacatcat attcattgta accgtgtaag
     3961 gctttaacaa tttgattctc tcactccagt cattttcacc cattgatacc cagacatcag
     4021 tataaataat atttgcacct ttaacgcctt gttcaatgtc atcagtaatc aaatttcttg
     4081 atccagaatc tttggcaaaa ccttctgcaa ttttttgtac atcagggtga gtgaataaag
     4141 gctttggcgt aactatgtgt acattaactc caagcatgct gccagccact aaaagactgt
     4201 cggcaacatt atcacgtcca tcgcctacat aagctaaaat aagtaccttt aaatgtccaa
     4261 acttttcttt aatagtcata aagtcagcca acatttgggt cggatgccat ttatctgtta
     4321 aaccattcca aacagggaca ccagaatatt tagccaaatc ttctacatct ttttgagcaa
     4381 aaccgcgata ttcaatgtca tcaaacatac tgcccaaaac cttggcagta tcttcaatac
     4441 tttccttttt acctaaatga atttcaccag cacccatata ttcaggattt gcgcctaaat
     4501 cattgcatgc aactacaaag gctgaacgtg ttcttgttga agatttttca aataaaagag
     4561 ctatattctt tccttttaaa tattcatgcg gaatattttc tttagttcct tcaaatgaag
     4621 tgcaaaatca attagatagt taagctccgt tggagtatag tctttgcatt ttaataaact
     4681 tctgccttga aacacatttt gtaaatattt cattttgacg cctcttacaa atcttcacga
     4741 acaagtggac atgacataca tcttggacct ccacggccac gagaaagctc acttgaatga
     4801 atttcatgaa ctaaaatgcc atgctttctt aacaaatcat ttgatacata attacgatca
     4861 tatgtaacga cttcacctgg cgcaatagcc aaagtattcg agccattatt ccactgctct
     4921 cttggggctg caattgcatc cccacctccg gttggaatta ggtcaatctc cgataagtgc
     4981 aaataattct ttaacacttt gatcaaatca gtttctgggg taattttaat ctcaccatga
     5041 tcatcttgct ctaaaacata aatatcaatc tttcctgatt tgtctaaaat aaaaggatga
     5101 acggtacact gatcataatt aatcattgta aagactgtat ccagatgcat catggcatga
     5161 ttatgtggta ttttaattgc taaaattgtg tcataactag aatgaccaaa caggctatga
     5221 gcaaggtcag tgattgcggc agcggaagtt atttgagaaa taccgattgc taaaaacatg
     5281 attgtttaaa atcagctcat cgccaccctc taaacgtcca tgagtgtaac gatcacgcca
     5341 aataggaata ttggcatttt taaagtcggg atgatgcttt aaaacggttt ccataaataa
     5401 tgactcacgt cttctagctc tagacgtcat tctattaata gtcatgccat taccaataac
     5461 tgcttgttga tcacgagtaa aatacacatt tagcattgga tccaaataaa atgaataaaa
     5521 tgaataatct ggatcttcag ctagatcggc taatgaagga gttgcatttt gtatttcatt
     5581 ttttctaata ccagcaatta tttgcttaac catttcattt actggcattg ctattaaata
     5641 gtccatcagt aattgatgta atggatcttc ttttttatat tggattcttc taataattga
     5701 tctacaaatt ttgtacggac atcttcatta gtcaaagagt gagctaataa atcttctaga
     5761 taaacgacat gaactcccta tttttccaaa gtgtgggcaa aatagtcatg ctctttttga
     5821 gctattttta aatatggaat atcgtcaatt aacattcgat ttaagatatc cggtgaaaga
     5881 ttttctaatt ctcttcccgg tcgatgcagc ataactgttt ctaatttgcc aatttcggaa
     5941 taaacatgaa ttaagtcagt cattatagcg tctcctaatt caaaattatg tatccgctta
     6001 caataattat tgatcaatta ggtagaagtt acaatcttaa cggcttagtg aatctattat
     6061 tcttttcatt aaaggcgtca ccttttgatc cttgcgccac actaattgca aatgcgtaat
     6121 ccaattacta tgtttaatag gaataagatc atcaggtgca tacgtagaag caatagattc
     6181 aggaacaaga gcaatcccca tttttctctt cgcccaagta atcgctgttc tagaatcatc
     6241 acatttaaca gcataaaacg gcttaatccc atgatgagca aaagtctggt taaaaatttc
     6301 ttcaaatctt cgataaataa tgaggggctg ctcatttaga tctttaatcc ttaattccgt
     6361 cttatccttt aatttgggat caacagtaac tgccatcatt ctttcagtag ttaaagtttt
     6421 tgcatttaag ccattacgat tataaggcgt acgcacaatt cctaaatcga ttgtcttctt
     6481 ttccaattta tcgataatgc caaaggtatt atcttcataa atatcaaagt tgatttccgg
     6541 ataaaactta gttaaatctt gaaaactttt cataggaatt agtccagttg atgatgaagc
     6601 catgcctatt gcaatcgtgc ctagttcacc tgaaacagtt ttatgaacct gatttttcac
     6661 gctttctgat aaagagagaa tttcactagc atagctctgc aaaatttgtc cagcatctgt
     6721 taattcaatt ccgtgagcag tacgcttaaa taattgtgct cctagttcta tttctagttg
     6781 ctttaattga taactcagcg gcggttgtgc aatgtatagt cttttagctg ctgaagtgat
     6841 ttgcttttct tcggctacta ctaaaaagta gcgtaattgt ttaatattca ttaataatct
     6901 atctttttta ttttagttgt atctcttatt aaaaaattct atatcttata ttttaattta
     6961 gtattttcat tcaaacaaca tatgtgctac tttattaagg tagatttgga gggaataaaa
     7021 tgtctgaaaa atttcatggc ttaactcaag ccgaagcaga taagagactt aaggaagatg
     7081 ggttaaacga agcacctgaa cccgaataca acttttttaa ggaatttcta tcaaaattat
     7141 ggaatctttc tgcctgggtt ctagaaggtg ccttaatcct cgaatgtatc ttaggcaaat
     7201 ggattcaatc tttgttcgtc ttgttgatgc ttctttttgc ggcttttaac ggtgcatcca
     7261 agaagaaaca gtcacggtgg gtattaaata ccatttcaca taagctaacc cctaaggtgg
     7321 ctgtagaacg cgatggtaag tggatcaaaa ttgactctaa gcaattagtt agaggcgact
     7381 taatctcact tcaacgtgga gatgtacttg cagccgatgt aaaaatggtt agcggtaaga
     7441 tcgcctgtga tgaaagctca attaccggtg aatctaagcc cgttaaaaag aacattgatg
     7501 acacagctta tgctggtact actgttgttg aaggcgatgg attagcaatt gttactgcaa
     7561 ctggtaaaga ttcaagaagt ggtaagacca ttaacttgat caacaattca gctgcacctg
     7621 gtcacttgca acaactttta actaagatta tttactacct ttgcctactt gacggtgtac
     7681 ttaccttagt tattatcatt gcttcattct ttaagggtgg taattttgat acgtttatca
     7741 acatgttgcc attcttagcc atgatgttca tcgcttcaat tccggttgcg atgccgtcaa
     7801 cctttgcatt gtccaattca tttgaagcaa cccgtttaag taaagaaggc gtcttaacag
     7861 ctgatttaac tggtatccaa gatgcagcta acttaaactt gcttttactt gataagacgg
     7921 gaacaatcac tgaaaacaaa actgcagttg ctagttggag cgatttaagc gatttgccag
     7981 ataaagatgt acttgcttta gccggtagtg caactgataa gcgcaatgca ggtatcattg
     8041 atatcgccat tgatgaatac ttaaaagaaa acaatatccc tgtcatggac gttgaacact
     8101 ttaccccatt tacttctgac actggctatt ctatggctga agtagatggt cacaatgtta
     8161 agttaggttc atttaagcaa ctttcgttaa tcgataagaa tgcaaatgaa gcagttgaag
     8221 gcatcaattt taaagctgga cgctcagttg ccgtgttaat tgatgacaaa cttgcgggag
     8281 tatttatctt acaagataaa gtaagaaagg actctaaggc tgctttagca gaacttaaaa
     8341 aacggggcgt acgtccaatc atgttaactg gtgataatca aagaactgcc gcagcagtcg
     8401 ctgaacaagt tgatttaact ggtaacgtta tctctattca tgactttgat gaaagcaccg
     8461 atattgatga attagcagga attgccgatg ttttacctga agataaactt aagatggtta
     8521 aattcttcca agaaaaaggt tatatcgttg gtatgactgg tgatggtgtt aacgactctc
     8581 ctgctttaaa gcaagctgaa gttggtattg ctgtttctaa cgctgccgat gttgccaagc
     8641 gttcaagtaa gatggtgctt ctagatgatg gcttaagctc tattgttaaa attcttgatg
     8701 ctggtcaccg tgtatatcaa cgaatgacta cttggtcact tgctaagctc gccagaaccg
     8761 ccgaattaac tatgctttta accttcggct atttcttctt caactatatt ccaatggcat
     8821 taaatgctat ggttatttac acaatcatga ataacatggt taccatgatg attggtaccg
     8881 accgtaccta tattacttac aaaccagaaa attggaatat ggcaaggtta gccaaaatcg
     8941 cattctctct tgctgcaggt tggacagtta tcggtatcgc ttttttcagc tacctcaaca
     9001 tgcatggctg gagtcacaat tctatctcta ccatggtcta tgtttactta gttctaagtg
     9061 caatgttaat tgtattaatt actagaactc gtaaatactt ctggcaagat tacccatcta
     9121 aacttgtagg tattgttcaa attgccgatg tcgcattaac ctttatttta gctttatgcg
     9181 gtttagcaat ggctcaaatt agttggcaaa acttattaat taccgttgtg gttgcattaa
     9241 ttgcagcaat tattattgat ttgatttatc aaccagtaat gaaaaacaga taattaactt
     9301 aaaacaaaaa cactctgaaa actacattac tacaatgtag ttttcagagt gtttttttga
     9361 ttaataatta gtaactgtag tcaaggcatt caaagcctta acatattcac catcagcaat
     9421 tttgataaat ggtttttcat taatttcttt atggcctaaa tagttaacct tagcaccacg
     9481 ctttaaaaat ttgcctggga ttttttcacc attctcatca taaacaaagg aatgcttttt
     9541 gattctatta actactttta cagtagtctt catatatggc aagaaggctt cttccttaac
     9601 aaatctattt ttacgaatct ttacataagt attaccatta attactttta tggcacgtac
     9661 tttgtaaagc tttccctttc ttaaatgtcc aactttaaca ccatgtctat tataaacagt
     9721 agcatttcta gttagattta atctcttacc ttgtctaact ggattagtaa caactgcatc
     9781 aacgctttgt gtagttgctg cgcctaatcc aataactgct aacattatac ctgcagcaga
     9841 aataatttgt tttctcatca taatccaccc ccgtagtgtt tataccattc tccatccctt
     9901 attttatcaa aaattatcga attggaagca ttttttactc atctgtttta taactatttg
     9961 cttaattctg ctaaaattat ttataatact acttaattca tgattttaac ttggaatata
    10021 atccgtagga ctatcgaagt cttatggatt atcaatattg cgtttgctgt atggacggtc
    10081 tttagaagtc gccgcagcgt tgttgcaact tgggcatgga tgcttgtatt aaccgttctg
    10141 cccggtatcg gttttatcct atatcttttc tttggtcgtc agctttcaca tgatgaaatc
    10201 tttgctattc aagaagagca aaaaaggtac aaagacatta tttagctgag caacgcaaca
    10261 tgcttaaaga gcacgatctt ctacctgaaa aagagcatct tccacgagta agaatgcttt
    10321 cggaactaaa tcttaacaac gatgatgcga ttttaacttt tgataatcag gtcaaagtat
    10381 ttatttctgg accagaactt tttgaccaaa tgattactga tatcaaaaat gccaaaaaat
    10441 ctgtcagctt agaattttat actttttatt ctaaccaatt agggcatctt gttttaaaag
    10501 ccttggaaga ggctgcagct aatggtgcta aggtaagagt aatttatgat acctctggat
    10561 caagaggcac taagccaagc ttttttgacc atttaagaga attgggcggc gaagctcagc
    10621 catttatttc cacttcaaaa aagcactggt ttactacccc acgactcaat taccacttac
    10681 atagaaaatt agttattatt gaccaccata ttggctatat tggcggattt aatattggag
    10741 atcaatatgt caataaatca ccaaaattcg gtcattggcg ggatacccat ttacgtgtaa
    10801 ttgggcaatc accaattcta atggaggtcc ggtttgcaat ggactggaac acgtcaatca
    10861 gaagaacaaa tttacctaaa tttgaattaa aggaacttaa accatttact gtcaatcgaa
    10921 aagatatcaa tgataataaa aatgtcgcta tgcaattgtt tcctcaggac ctgataatca
    10981 acattacggc atcagacgag gctgagggaa ttattgcagg agctaaaaaa tacatttata
    11041 ttcaaacgcc ttatttaatt cccgaagaat caattcttga agccttaatt atcgctgcta
    11101 acagcggtat tgatgttcga attatggttc cttgcatgcc cgatcatcca tttgtttatc
    11161 gtgctacaga atactatgct aagtatttag tagcccatgg cgttaaagta tacaaatata
    11221 atgatggttt tattcatgca aaaactatgg ttagcggttc taatatttct tcagttggtt
    11281 ccgccaatca agatttccga agctatacat taaactttga ggtaaactca ttcaactaca
    11341 accctgcttt aactcaagaa ttaaagaaaa tttttgagaa ggacttagat aaatgtaccc
    11401 ttttaactaa tgactacttt gctcaacaat cattatggtt aaaatttaag caatacttct
    11461 caagattatt atcacctatt ttttaatgaa aagccctcta tcggtttatc cgataggggt
    11521 tttactttgt attttaaaaa tgcagtttta tttctttact tattttttat aggttatata
    11581 atgataacta ttaaaaagta aggaggataa aacttggcta atagagtaaa aataggcgtt
    11641 ttgaatttaa tgcacgataa gttagatact caacaaagat ttgcacgcgt tttgccagat
    11701 gcagacctga ctttctttta tccacgtatg cattatcaaa atcgtcctgt cccacctgaa
    11761 gttgcaaaaa cttcccagcc attagatctt aatcaaatca aagagtttga tggctttatc
    11821 attacgggcg cacctttaga tcatcttgat tttgatcaag ttacctacat cgaggaagtc
    11881 cgatgtttgc tccaactatt agataaatac aagttgcagc aattatattt ttgctggggt
    11941 gcaatggccg ctttagatta tttttacaat attcaaaaaa gaattttatc gaaaaaaatc
    12001 tttggtgttt ttcctcattt aattatcgaa ccacatcctt tattaaatgg actcagcaaa
    12061 ggatttatcg ctccacatgc tcgttacgct gaaatggata aaacacagat tatgcaagat
    12121 ccacgattaa ccattaattc agttgacgat aatgggcatc tatttatggt ctcttcttta
    12181 gaaaagcctg agcaaaattt tattttctct catatcgaat atggccgaaa aggccttaaa
    12241 aaagaatatg aaagagagat tgctgcacat ccagagcgac attataagaa gccagaaaat
    12301 tattcattat caaatctatt gtttcaatgg aaagatactc agaaaacatt tttcaataac
    12361 tggctaactc aagttaaaaa aagcaaatta gtattattag ataaataaaa cgaggcatac
    12421 attatgtcta caatttataa ttcagttaca gaacttatcg gcaacactcc attacttaag
    12481 ttgaatcgcg ttgtacctga cgacgcggca gatgtctatg taaagttaga atttgaaaac
    12541 ccagctggtt caattaaaga cagaattgct ttagctatga tcgaaaaagc tgaacgtgaa
    12601 ggcaacctaa agccaggtgg cacaattgta gaacctactt caggcaatac cggtatcggt
    12661 ttagccatgg ttgctgcagc taaggactat cacattatta ttgttatgcc agaaactatg
    12721 agcgttgagc gtcgtaaatt aatgaagggc tatggtgctg aacttatttt gacaccaggt
    12781 gcagacggta tgaaaggttc aattgctaag gccgaagaat tagttaaaga aaaaggctac
    12841 ttcatgccaa tgcaatttga aaatacagaa aatcctaata ttcatgaatt aactactggt
    12901 ccagaaatta ttgccgcaat gaatggtatc ggcaaatccg ttgatgcctt tgttgctggt
    12961 gttggtactg gtggtacttt atcaggaatt ggacatgcac ttaggcgtga aaatccatcc
    13021 actaagatat ttgcacttga gccaactgaa tctccactct taaaagatgg aaaaacaggt
    13081 aaacatggta tccaaggtat tgccgcaggt ttcatcccta agaatttaga taaggatatc
    13141 tacgatgata taattacagt ttctactgat gaagcaatgg ctacagctcg tgaagtagct
    13201 aaaaacgaag gcttcttacc tggtatttca gctggtgcaa acatccatgg tgcaatcgaa
    13261 attgctaaaa agttaggcaa gggacatgct gtggttactg tagttccaga cggcggtgat
    13321 cgttaccttt caactgcatt atttaatgct taaaacttaa tttctgtaaa caaatactcc
    13381 taagtaaaat ttccttagga gtattatttt tatttctgtt gattgtgcac cagtcaatgt
    13441 tggtacaaca cttttagtat aatgaccttt actaattaga tcaatattga atttatttaa
    13501 gccccatgat attgcactaa gctgtaaata tcaacatcag gcaacttttc tctacccttt
    13561 aaatcaggca attcaatgta aaatgcagca cctacaagct taccaccaag attttcaatt
    13621 aattccttag aagctcttaa agtacctgca gtagccatta aatcgtcaca gagaacaact
    13681 ctttggccag gcttaattgc atctttatgc atttcaaggc tatttgaacc gtattccaag
    13741 tcatatgaag cacgttcaac ttctcttggc aacttatgtg gctttcttgc tggaacaaaa
    13801 cctaagccta actcagttgc aacaggacag cctacaataa agccacgtgc ttcaggacct
    13861 acgattacat ctgcctttct actctttgca tattctgcca attcatgagt agcaatacga
    13921 tacaattcac catcttgcaa aataggtgta atatcgcgaa agacaattcc cttattagga
    13981 aagtccttaa cacttgcaat atatttacta aaatcaatcg ccataagaag aaaaacctcc
    14041 ataattctgt gcgtttgtat tcaaacactt ttgacttgta tattttacca aagatttgtt
    14101 ataaaagtac tgaaatcttg atatttatct atctttttac caaattatta acatatgtaa
    14161 ttaatttttg agtaggcatc gttcttagtt gattaataaa tttaatttgt gaactcgttg
    14221 ccattaaata tttagaagct gtcaatggtt gcttctttgg attagactca ccaactaatt
    14281 tttgatcgtc taatttaaca aaacctaatt caaagaatac tcgcaaaata aacaatacac
    14341 tatcataatc caaacctaga tatggtgcta cagtgcgata gtcttcaggc tttaatgctg
    14401 gatgggcata aatatacttt aacacttttc cgaaataact ctttgctgga atttgttcaa
    14461 caggtaactg atctaataaa aagcataaat aaatttgttg ataatctttt tttaaagctg
    14521 catttaattc cacttgattg cgaggcacat caagcaaagc tactgtttca cccgattgat
    14581 cataatcttt aaccaagcta attttatcat catcaatttg aaggcgattc ttaacaattg
    14641 gaatattctt tttgtcaaaa agcaaataac gatctgcaag gcccatgaca aatttctctt
    14701 gtcttaaatc aattactgat gttggcacag ctaattttgg ggatgcaaag gctattcctt
    14761 ccatgatgcc ttgcaaagat acttgtttgc gataagtatt caaagaaaga gtaacaaaga
    14821 tttttgaaat aaatggtaac aaattattat tcaaataatc cttattaaat cccacaattg
    14881 ctaaattgcc gtctttttta ttagctgtta atttaacatg attcttatct tttcctattt
    14941 tgaaaaagtg tgtaatagtt ggatccgaaa tactaaaaat tggctgcgga tcaccagtac
    15001 caaatggtcc cacttgatta atttgagcca aagtttgagg tgataggtca tgcataggca
    15061 attccatatc gtactcttta gtctctaaac caccgtcaac atgaaaatcg gcttcaaact
    15121 ttttccgtag gtcatttact ttgtcttctt ccatggataa accacaagca aaatcatgac
    15181 ctccaaattt ggtcaataga ctttctttta acggattaag agcatcaaat aagttaaaac
    15241 cactgaatga acgacctgat cccttaatct ccccttcatc gtttttagtt aaaacaattg
    15301 ttggtttatg cagtttttcc actatcttgt tagcaacaag ccccaaaact ccttcatgaa
    15361 aatcaggatc atataaaact aaagtatttt gcttttgcca actattttca cgaactaatt
    15421 ccatgcagcg atcgtaaacc tcagtagtta gctctttacg cttattattt aagtcttcaa
    15481 tctgatctgc gatcttctgt gcctcaagat catcatcact aagcaaaagc tctactgcca
    15541 gattagcatt agccaaacgt ccaacagcat taagtctagg agcaatatta aagcctacat
    15601 ctgtctcatt aatcgtttct agcgttaaac cggcattttt gataagcgct cttaagcccg
    15661 gtcgttcggt ttgattaaga acatctaacc cacgttttac aataatatgg ccttcaccag
    15721 taactttaac catgtcacca atagtaccga tcattgctaa atctagcaat tctggtacag
    15781 gatcctgcat aagctcacga caaattgtat aagctacacc tgcaccacaa taatcatcaa
    15841 aaggatattc ttgaccagga taattacagt gaacaattgc ataagcatct ggcttatttt
    15901 cttgaaaagt atggtgatcc gtaataatag tatcaacgcc atgttcttta gcgtattcaa
    15961 cttcttcaat ccccgttaca ccattatcta cggtaataat taactttgtg ccatcag
//
