LOCUS       c00078_gnlPro..        17113 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FBDIMLML_160.
ACCESSION   c00078_gnlPro..
VERSION     c00078_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 10:54:42
            Original ID  :: gnl|Prokka|FBDIMLML_160
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17113
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17113
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8897:11755]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8898..11755
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..17113
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17113
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             1966..2205
                     /locus_tag="ctg78_1"
                     /transl_table=11
                     /translation="MSWLHNSDEVKALTSRQVGWLMKGFSIDPKIKNLKTVSVLQILRR
                     LLDTFNYMTFTIERTAFGYSDTLSTGFLEKEPEY"
     CDS             2234..2323
                     /locus_tag="ctg78_2"
                     /transl_table=11
                     /translation="MSKVLDSHHITTKTVISQYTHLHDTYNKS"
     CDS             complement(2404..3984)
                     /locus_tag="ctg78_3"
                     /transl_table=11
                     /translation="MMDIQNKQKNIFFRNVINRIGKLRVLILILLVFLGYLLYYCQPYF
                     ISNLFYNKDTNKNILNFIGLGITLLVTPMINILNNNYVQAIRVYSKKELWEKVSNEEYS
                     YFLDSTIGKIQSYINEVSFACREIEQNSLLQMIKLFAMLFLYTIMLIKLNIMLGIIYLV
                     IFVCYMILSTKMANINRMRIAQSLSKTSKINENMQDYYQNIEVILSSNSQKFEDKKIDH
                     TLNDEKEVYYHVQQVTNFNTLVQQFIVIALAAIICIFGMYTLHAKNLFSVILILLYSVL
                     NLASFGMQYLAFRELSDRISSGLKVLKYDVNLKKKKENFVYNDSQNSIQLQNLSFKYSN
                     KKKVFSNLSGSFPKAKMSAIIGENGRGKSTLLKIIMNFYPLRYGTIIFPYKDPLIVYIP
                     QNAPLFNRSIYENISYPGKKISVDFIMKLVTEIGLDSLIKSKKDLKNKKPGDFKNSISG
                     GERQKILFLRAIVSKPDILLLDEITSNLDEKTVTLLYRLIRKYLKNTTIIGITHRQEEL
                     KYYDYIFRL"
     CDS             complement(3965..5413)
                     /locus_tag="ctg78_4"
                     /transl_table=11
                     /translation="VVNGGYGTPIVFKNLVFCLNSFDSIAAYNKNNGKYLFNRKFDDRI
                     RSSMNVIDGYIWFSHTSHLIALDENGKIIHDFHVPNAFLYGTVSKYQDELIIIGTKYIQ
                     DENTSNKFIWAIDKKNGNKLFEVNLGVGSIISTDISGFWFQKGYIYASNNDKIFKISAQ
                     NGKIVWQRKVNGNVHRHTVIADSQAVYYTTLKGEFGSLKLKNGTVNWKVNIEEGIITPP
                     TVINGSLLIIGDSSIYVVDKKEGLIYQKIPTGHSPYSAATIFRNRVFLGAGEPPINGLL
                     FCFEFNQGVNNNLEISQDFYVGNTLNSKKLQLTIETKNNWDEVIIDPSVLSDAAEIKGQ
                     KIGNNIFVFQIPLKNTNINSWYTLSIKLKEKRQIKIVTTAIKIRRTDQLPRKVTLSNFN
                     KIANESTPFNSGSALTQMIEEEYGKKISQEDFRDIIDYLKKTSKWKDADFQTWRLLLKR
                     ALSSPAKDLNEFIKLEDENDGHPE"
     CDS             complement(5756..6103)
                     /locus_tag="ctg78_5"
                     /transl_table=11
                     /translation="MVAADTTYGNGNGAVVTVPKKMQGTWYSYDSNAHSGRKITFTAHT
                     VNGKIIYTQDKSIISDYFNGNIQDQAGFDRATKNWMSGQTTKMKNNLFYEINPWISFEN
                     WSLYRVMPLTI"
     CDS             complement(6090..6197)
                     /locus_tag="ctg78_6"
                     /transl_table=11
                     /translation="MLERKLLPLLAMVLALGLSGLTTHVKAADTTYGSG"
     CDS             complement(6274..6879)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_7"
                     /sec_met_domain="LysR_substrate (E-value: 8.1e-19,
                     bitscore: 58.2, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEEAVIKDFILLAKKVY"
     CDS             complement(6882..7043)
                     /locus_tag="ctg78_8"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLSVVVSGINVVISLLIMFNKYQIRKDKKQIADE
                     GHAPLDEN"
     CDS             complement(7059..8225)
                     /locus_tag="ctg78_9"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIEYAFLKDSDLTTDSNFMPRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQK
                     IPVANLAPFLEKFYRHYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHTDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMAAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLSCMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             complement(8345..8881)
                     /locus_tag="ctg78_10"
                     /transl_table=11
                     /translation="MNIFQEGNLQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNKGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTAFSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             complement(8898..9239)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_11"
                     /sec_met_domain="AA_kinase (E-value: 4.4e-19, bitscore:
                     59.4, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGLAGVIDKDFSAAKLAEDIQADELVILTAVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDFIEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             complement(9408..9830)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_12"
                     /sec_met_domain="AA_kinase (E-value: 5.9e-13, bitscore:
                     39.3, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVALGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNPAMPLDTVVAMTQGSIGYWMQKALDDQFKHTNYPH
                     QAVALITQIIVNANDPTFKNPTKPIGPFYTFNEMQR"
     CDS             complement(9833..10633)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_13"
                     /sec_met_domain="OTCace (E-value: 2.3e-50, bitscore: 161.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 1.7e-25, bitscore:
                     80.2, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDGIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPTQMLADFMTIKEKFGHLKGLTLAYVGDGRDNVADSLLVSGSMLGV
                     NVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIEQGVKGANIIYTDVWVSMGEND
                     WSERIKLLKPYTVTMKMMYMTGTPDDQLIFMHCLPAFHDRTTKVGKEIYEKYGLSEVEV
                     TDEVFNSQYAWQFTEAENRLHSIKAIMAAALGNLFIPSVDEGSK"
     CDS             complement(10881..11435)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_14"
                     /sec_met_domain="Amidinotransf (E-value: 1.2e-52, bitscore:
                     169.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLAIGISQRTSAAAITDLAHSLFGHSSYDTILAIKIPHNHAMMH
                     LDTVFTMINYDQCTVHPFILDKSGKIDIYVLEQDDHGEIKITPETDLIKVLKNYLHLSE
                     IDLIPTGGGDAIAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGILVHEIHSS
                     ELSRGRGGPRCMSCPLVREDL"
     CDS             complement(11383..11601)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_15"
                     /sec_met_domain="Amidinotransf (E-value: 6.4e-14, bitscore:
                     42.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINRMTFRARRRESLFMETVLKHHPDFKNANIPIWRDRYTHGRL
                     EGGDELILNNHVFSNRYFSKNFRCRNH"
     CDS             complement(11591..11755)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_16"
                     /sec_met_domain="Amidinotransf (E-value: 3e-09, bitscore:
                     26.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDY"
     CDS             complement(11828..12682)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     73.6; E-value: 3.1e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg78_17"
                     /sec_met_domain="LysR_substrate (E-value: 2.9e-30,
                     bitscore: 95.6, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1e-23, bitscore: 73.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAEEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESLKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKFKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYVPDDLIPIKHSNWITHLQLVWRKDQKVTPLMKRIIDS
                     LSR"
     CDS             12811..15084
                     /locus_tag="ctg78_18"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKENGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKNNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDAFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSDLSDLPDKDVLALAGSATDKRNAGII
                     DIAIDEYLKENNIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMT
                     RLAKIAFSLAAGWTVIGIAFVSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(15152..15649)
                     /locus_tag="ctg78_19"
                     /transl_table=11
                     /translation="MRKQIISAAGIMLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTRN
                     ATVYNRHGVKVGHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKSTVKVVN
                     RIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTAVT
                     NH"
     CDS             15791..16798
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_20"
                     /sec_met_domain="PLDc_2 (E-value: 2.4e-17, bitscore: 53.5,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILTWDIIRRTIEVLWIINIAFAVWTVFRSRRSVIATWAWMLVLT
                     VLPGIGFILYLFFGRQLSHDEIFAIQEEQKKVQRHYLAEQRDMLKEHDLLPEKERLPRV
                     KMLSELNLNNDDAILTFDNQVKVFISGPELFDQMITDIKNAKKSVSLEFYTFYSNQLGH
                     RVLKALEEAAANGAKVRVIYDTSGSRGTKPSFFDHLRELGGEAQPFISTSKKHWFTTPR
                     LNYHLHRKLVIIDHHIGYIGGFNIGDQYVNKSPKFGHWRDTHLRVIGQSPILMEVRFAM
                     DWNTSIRRTNLPKFELKELKPFTVNRKDINDNKNVAMQMVSSGPDNQHYGIRRG"
ORIGIN
        1 cgaccgccag ctgcacttta tctgcttgga tggcgataat catcaggtcg ttcagattct
       61 tagaactcgc tacaagaaga ctttgcttaa gtattttggg cgtttctcgc ctcaagctag
      121 agctaatgtt aaaacggtca cgatggatct taatttttac tatcaagata tcgtcagagc
      181 ttgttttccc aatgctcaga ttgtcatcga tcgttttcat atgatccaaa tgcttacccg
      241 atcattcaat tcgttgagag tccaggtcat gaagaccttc gacaagaaat cacggcaata
      301 tcagctgctt aagtctcctt gaaaattata cttgaagaag ttcaatgagc tcgaaaaggt
      361 tcatcctcgc tataattggc attataaaga ctgcttaact caagcccaag tagtcacaga
      421 aggcatcagt gccaatactg ctttagagaa ttcatataac ctgatgcagg actttattca
      481 agccattgaa actggcaata ctcaaaagct taaatcatta atcaactgca aagatcaaat
      541 tggaactcta atgcataaan nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      661 nnnnnnnnnn nnggcagtgc ttaatggagc agagctagct tattctaatg gctgtcttga
      721 aggcttcaac cgcaaaatca aacaaatcga acgaacagct ttcggctatt ccaattttat
      781 caatctatta accagaattc gtttggaaga agatctgtac aaagaaaaag aaccaaacag
      841 ccttttaatg actgcctgat tctattcatt tactctctat caacaggatt tgacaaagag
      901 ccgaaaaaac tcagaaattg aaaaatccta ctaaatcttg gtgttaacaa accttgattt
      961 agtaggattc ttgttttaag ctaaagtcta aaattaatta aaaatagact ttttccccag
     1021 acacttctac ttgtaaattt attcagaatt atcccaattg ctttcaccat caaagagtta
     1081 cgttcttctt gtgctaggct atcctcttat tcgatcgctg atgttaaagc ttgctcggct
     1141 ttgcctgtcc acaagatctc tcggggtaag acattcatct ttggctttcc actgcctcct
     1201 ggtttaccgt cttggcttta cgtttgtcat taggacttcg acttgtcaag cagtcttatc
     1261 cgccatttgg cctgaccagg tttctttacg tagactcgga gaactcgcta gccacttcct
     1321 tcacccatag cgtcaccgct accggcttgt ggttcactac acttggcgac actacccatg
     1381 atccaaactt tcattgaact agataaatgt catgctcgac acacttgaaa aggcatcgct
     1441 taattgcaaa ataattaagc gatgcctttt ttgctttcta tttgcagatt gtctgaacgg
     1501 taagcgcact ataaccaagt gtcttctata gtcccatctt ttcagttcat caacttaagg
     1561 aggcaaagaa aatacttaaa aaacaaccaa tcgtagcact ggatcaccca gtcagaacta
     1621 agaagatgcg gccaccacgc aatactctgc tgctcagcct gaaaaagaaa gatttagaat
     1681 caaatttcta cagcagctta gaccctaaac taatgaataa gttgttagaa aaggttctat
     1741 cacgatcaag ctgagcgatc tgggacaagt ttatatcgtt tgcggcaaaa tcgacctgtg
     1801 caaaggcatt gatggcttgg ctgctttagt ccaagagcag tttgatcttg atccatttag
     1861 cggaaaattt tttctctttt gtggtggtaa gcaagatcgc gtcaaagctc tctattggga
     1921 cggtcaaggg ttctggcgct ctataaaaga tttgaaaacg gcaagatgag ctggctgcat
     1981 aattcagatg aggtcaaagc ccttacttca aggcaggttg gctggttaat gaagggcttc
     2041 tcaatcgacc ctaaaatcaa gaacttaaaa accgtctcag tattacaaat actgaggcga
     2101 cttttagata cattcaatta tatgacattt acaattgagc gtacagcttt tggctattca
     2161 gatactctat caacaggatt tcttgaaaaa gagccagaat attgaaatat agttttaaat
     2221 agagcaatat aatatgtcca aagttttaga ttcacaccat attacaacta aaacggtaat
     2281 ttctcaatat actcatttac atgacactta taataaatct tgatttaaca tctatataaa
     2341 tcagccgcta gcactatttt attaagttag tattttttag tacactatca ttaaatattt
     2401 tgattacagt ctaaatatat agtcataata cttaagttct tcttgcctat gtgtaattcc
     2461 tattattgta gtatttttca aatattttct aattaaccta taaagcagcg ttacagtttt
     2521 ctcatctaaa ttacttgtta tttcatcaag caacagaata tctggttttg acacgattgc
     2581 tcgtaaaaat aagatttttt gtctttctcc accagatatt gaatttttaa aatctcctgg
     2641 ctttttattt tttaaatcct ttttactttt tattaatgaa tcaagtccta tttcagtaac
     2701 taatttcatt ataaaatcta cagatatctt cttacctgga taactaatat tttcataaat
     2761 agaccgatta aataatggag cattttgcgg aatatatact atcagaggat ctttatatgg
     2821 aaaaattatc gttccatatc tcagaggata aaaattcatt attattttta ataaagtact
     2881 ttttcctctt ccattttctc caatgatggc tgacatcttt gcttttggaa aagatccact
     2941 taaattggag aatactttct ttttattcga atatttgaaa gataaatttt gtagttgaat
     3001 actattttgt gaatcattat acacaaagtt ttcttttttc tttttcaaat tcacatcata
     3061 tttgagaact tttaatcccg aacttattcg atcgcttagt tccctaaaag ctaagtactg
     3121 catgccaaaa ctagctaaat ttaaaacaga atacaataat attaaaatta ctgaaaaaag
     3181 atttttggca tgtaatgtgt acatgccaaa aatacatatt atagcagcta aagcaataac
     3241 tatgaattgc tgaactagag tattaaaatt agtaacttgt tgcacatgat aataaacttc
     3301 tttttcatca tttagagtat ggtcaatttt tttatcctcg aatttttgtg aattagatga
     3361 taaaattacc tcaatatttt gataataatc ctgcatattt tcattaatct ttgatgtttt
     3421 acttaaagat tgcgcaattc tcattcgatt aatattagcc atcttagttg acaaaatcat
     3481 ataacataca aaaataacta aatatattat tcctagcatg atattaagtt ttataagcat
     3541 gattgtatat aaaaataaca ttgcaaataa tttaatcatt tgcaacaaac tattttgttc
     3601 aatttctcta cacgcaaatg atacctcatt aatataactt tgtattttgc caattgtaga
     3661 atctaagaaa taactatatt cttcattact cactttctcc cacaattctt ttttagaata
     3721 aactcttatt gcttgtacat aattattgtt taaaatatta atcattggtg tcactagtaa
     3781 tgtgattccc aatccaataa aattcaatat atttttgttt gtatctttat tataaaaaag
     3841 attcgaaata aaataaggct gacaataata taaaagatat cctagaaaaa ctaatagaat
     3901 taatattaaa acccttagtt ttcctattct gttaatcaca tttctaaaaa aaatgttttt
     3961 ttgtttattc tggatgtcca tcattttcat cttctagttt tataaattca tttaaatctt
     4021 tagctggact actcaacgca cgcttaagta ataatctcca tgtctggaaa tctgcatctt
     4081 tccatttgct agtctttttt aagtaatcaa taatatctct aaaatcttct tgagaaatct
     4141 tcttaccata ttcttcctcg atcatctgtg ttaaagctga gccactatta aaaggcgtac
     4201 tttcattagc tattttatta aaattagata atgttacttt acgtggtaat tgatctgtcc
     4261 tacgaatttt tattgctgtg gttactatct ttatttgtct tttttctttt aactttattg
     4321 atagcgtata ccaactattt atattagtgt tttttaaagg aatctgaaat acaaatatat
     4381 tattgcctat cttttgtcct tttatttcag cagcatcact taaaacagat gggtctatta
     4441 ttacttcatc ccaattattt tttgtttcaa ttgttagttg gagtttttta ctattcagtg
     4501 tattaccaac gtaaaaatct tgtgagatct caagattatt atttacacct tgattgaatt
     4561 caaagcaaaa taataatcca ttaattggag gctcacctgc gcctagaaat actctgtttc
     4621 taaaaatggt cgccgcacta taaggtgaat gcccagttgg aattttttga tatattaatc
     4681 cttctttctt atctacaaca tatattgaag aatccccaat tatcaataaa ctaccattaa
     4741 ttacagttgg cggtgttatt attccttctt ctatattaac tttccagttt actgttccat
     4801 ttttcaactt taaggatcca aattctccct ttaaagtagt atagtaaaca gcttggctat
     4861 ctgcaattac agtatgacga tggacgtttc cattgacttt tctttgccat acaattttgc
     4921 cattttgagc agatatctta aagattttat cattattaga agcatatata tatccctttt
     4981 gaaaccaaaa accagatata tctgtactaa ttatagatcc aacacctaaa tttacttcaa
     5041 ataatttatt accattcttc ttatcaattg cccatataaa cttattggaa gtattttcat
     5101 cttgaatata tttagtacct ataataataa gttcatcctg atatttggag acagttccat
     5161 acaaaaaagc atttggaaca tgaaaatcat gaataatttt accattttca tctaaggcaa
     5221 ttaaatgact ggtatgactg aaccaaatat agccatcgat tacattcata gacgatctaa
     5281 ttcgatcatc aaactttcta ttaaataaat actttccatt atttttatta tatgcagcta
     5341 tagaatcaaa actatttaaa caaaaaacca aatttttaaa tacaatcggt gtaccataac
     5401 ctccatttac cacatgggtt tgccatttaa tatctccagt gatttgatta aatttagtta
     5461 aaatatattc ttgttttttt cagaataggc ttctacatac gctgaagtat catcctcata
     5521 atcaaagaat acagtacgta tcagccatgg atacttcttt atccatttga ttgacaatga
     5581 aactagatca gaatgactta tatgaaccaa attttttcta aacatataac ttacactttc
     5641 taaaaaacac ttggatattt catccaagtg ttttaaaaat taatgtccct ctgaaatttc
     5701 tttttcttcg cttgttttag tgcttgcaga agatacatta agttcagagt taaacttata
     5761 ttgtaagagg cattactcta tatagactcc aattttcaaa actaatccat ggattaatct
     5821 cataaaatag attatttttc atcttagttg tttgacctga catccaattt ttggtagctc
     5881 gatcaaaacc agcctgatct tgaatattgc cattaaagta atcgctaata attgatttgt
     5941 cttgagtgta aatgattttt ccattaaccg tatgcgcagt aaaagtaatt tttctaccgc
     6001 tatgtgcatt actatcatat gagtaccatg tcccctgcat cttcttaggc acagtcacaa
     6061 ccgctccgtt accattacca taagtggtgt cagccgctac cataagtggt gtcagccgcc
     6121 tttacatgcg ttgttaatcc gctcaagcct aaagccagta ccatggctaa caaaggcaat
     6181 aattttctct ctagcataaa atcatctcca gttgtaaaat tatggattcg ctttcattgt
     6241 taattttaca ttattttgct gttccaagat agattaatat acttttttag ctaacaaaat
     6301 aaaatcttta attactgcct cttcattggt ataaaaagct gcaatctttt gccacatttg
     6361 ttgtccatta gacaataaaa acaatcgttg taaagtatca ttactaatta aactggcggt
     6421 tgcttcattc attaaaaaat atcctgatcc agaagctact aacaatgctg cctcttctac
     6481 ggaatttgaa gcaatgaatg ggcttctaat ctgataaata tctttaaata aatggagttc
     6541 tgcagcctct tcttcaggct tagctacaat aaaacaggtt aaatcagcta gatcatcttt
     6601 attgatcatc tgaacaccgc taggataact acccttttgc aaaatagcca ttactgcttc
     6661 ctgacctaag atttctttct taaaatcgag ctgatcatcg cgcaaatcac taatcgctaa
     6721 atcaacttca tttttggcta atttatcaaa agcttcatcg tgtcccattc caattaattc
     6781 aatttctaca tcagaatgtt tttgcttaaa ttggtctaca attcgatcta attgtcttct
     6841 accaagttgg ttaaagtatg ctattctcaa ttttttcata gttaattttc atccaatggg
     6901 gcatgacctt catctgctat ttgtttttta tcttttctaa tttgatattt gttgaacata
     6961 atcaatagcg aaataaccac atttattcca ctaactacca cgcttaaaaa ttttagtaat
     7021 ctaactttct tttgcttact cattttggat accttcttct aaaaataatc ataaaatgag
     7081 actttacctt ttacaaagtc caacttttta attcgataat ctgtgatcaa accaagttta
     7141 attgcggatt ccatagttaa acgtcctaat aagatttgag tccatgttgt aattggacca
     7201 gagaaatcaa ctagttcatc ttcttttcgt tcacacttaa cttggtgatc ataattagtt
     7261 aattgccaaa cgccaatatt ccatggacac tgatcatcat aattaacttc gatgttaaaa
     7321 gtaccctctt gcaatgggcg catgcatgac aagacttttt ggaaatcaat aattctactc
     7381 atcatatatg gatgaagttg aatatccaat tcattttgct ctggaaaaag ttcagccaat
     7441 aaagacttct caggcaatgt catacaaaac tctttaattg accctatatg agctgccata
     7501 aagcctaata tgcttaataa tccttgaggc gtaattgaat ataattcatc agccataaaa
     7561 cagttatcaa ttatgcgata aatcaagtag ctcatcggcc gaccagcttc atcgaagtaa
     7621 acagcaatct ctcgatgatg ataataatca tctaatctat tccaccacca agcttctctg
     7681 atgatcgtat ttctttcatc gtcagtatgc aactgacgtt catataattg aatcacacca
     7741 ttttgaacaa tcaaatcatt ccattttcca cgaattatct tacctttgcg tggtaatctg
     7801 aaagaagcaa gtgcagcccc cgaaaagcga tattcttttt ggtaaatact attgctaaaa
     7861 ccataatgac gataaaattt ttctaaaaat ggagctagat ttgcaactgg gattttttga
     7921 tcatgcaaat caaaaagaat ttctttcatt aatttagata tatgtccacg tcctctgtat
     7981 tcaggatatg atgccacata accaatacct gccagtggaa catgatgacc aaatatctca
     8041 gctttaaact tattgaccat catataactg gtcaattttt cttgatcaaa atatccatat
     8101 ccatcactat gatcatatcg gggcataaag ttactatctg tagtcaaatc agaatctttt
     8161 aaaaaagcat attcaatcaa tgaagcaatt tgttttaaat tgtcttggtt tttctttaat
     8221 ttcatagttt tccttacaat atatattcat aactttactt atattttaga acattttatg
     8281 tatttttcgt tagctttttt aagatttaaa tgaaaaaacg ggatgattag cctcccatcc
     8341 cgttttaatt atttacatac ttcgcatata aactagaaat gtatctttgc atctcttcta
     8401 ctgagtgtcg ccgtgatcga gcacactctt tagcagggcg attgcataaa tagcagcggc
     8461 gactagagta ttcaagctct tggcgtgaaa atgcagtttt ccctttaatt aatacatcgg
     8521 catcaaataa tcgtcctatt ttattatttt cttcaaataa aattgtagat aatttaacta
     8581 ctttgctaga ttctcgcaaa acatagaaat tttcacatcc agcatcatta tttaatgctt
     8641 ttactaattt atagtcatat cccttattct gccatatttc ttctaattgt ttaattccgt
     8701 aatcaaataa tttgattaaa tatcgattat ttttaattgg ccccgggata tttaagttta
     8761 tatcaaccaa agtcgcatca ggatactttt taaaaatagc ttgctgcaaa gctacacgat
     8821 aatctttccc agctaatacc tgagcaatat tttgcagatt tccttcttga aaaatgttca
     8881 tttatatctc accgcagtta attataaaca attgtaccta ctccatcatc aagtttactt
     8941 gcatttctta aagaagtaat aattgcagtc tttcctgttt tctctatgaa atcaatgaca
     9001 gcttcaattt ttggcttcat gctgcctgca gcaaattggc cagcttctag atacttcttt
     9061 aattgatcaa tctttatttt tccaatagga gcttgatcag gttgattata gttcacgtag
     9121 gcattgtcaa cagcagttag aataactaat tcatctgctt gaatatcttc agctagtttt
     9181 gcggcactga agtctttatc aattactcct gctaagcctt gcaaactatc gtctttcact
     9241 acaacaggaa ttccaccacc tccggcagca ataggaacaa acttgctctt tagtaaagtg
     9301 tcaatgcctg gtgcattaat aattttaacg ggctttggag aagaaactac ttgacgatag
     9361 cctcgacctg catcttgctt ataagtatat tcaggatgat agatttttta cctctgcatt
     9421 tcgttaaatg tataaaatgg gccaattggt ttagttggat tcttaaaagt tggatcattc
     9481 gcattaacta ttatctgagt aattaaagca acagcttgat gtggataatt tgtatgttta
     9541 aattggtcgt ctaaggcctt ttgcatccaa tagccgatac tgccttgagt cattgctact
     9601 actgtatcaa gcggcatagc gggattatct ttacttgaac ctttgtattg ttgcaaaagc
     9661 aaattaccaa cctgcgggcc attaccatga acaatcgcta cctgatcacc attttcaatc
     9721 attttagcaa caaccttcat tgtcttttta acctgctttt cttgggcagc tgcactatta
     9781 tcacctgctt caatagcatt gccacccaaa gctacaacta ttcttttcat ctttatttac
     9841 ttccttcatc aactgacgga ataaacaaat tgcccaaagc agcggccatt attgctttga
     9901 tagaatgcaa tctattttcc gcttcagtaa attgccaagc gtattgagag ttaaagactt
     9961 catctgtaac ttccacttca cttagaccat atttttcata aatttctttg ccaactttag
    10021 tagtgcgatc atgaaacgca ggcaaacagt gcataaagat tagttgatca tccggggtgc
    10081 ctgtcatata catcatcttc attgtaaccg tgtaaggctt taacaatttg attctctcac
    10141 tccagtcatt ttcacccatt gatacccaga catcagtata aataatattt gcacctttaa
    10201 cgccttgttc aatgtcatca gtaatcaaat ttcttgatcc agaatctttg gcaaaacctt
    10261 ctgcaatttt ttgtacatca gggtgagtga ataaaggctt tggcgtaact atgtgtacat
    10321 taactccaag catgctgcca gacactaaaa gactgtcggc aacattatca cgtccatcgc
    10381 ctacataagc taaagtaagt ccctttaaat gtccaaactt ttctttaata gtcataaagt
    10441 cagccaacat ttgggtcgga tgccatttat ctgttaaacc attccaaaca gggacaccag
    10501 aatatttagc caaatcttct acatcttttt gagcaaaacc gcgatattca atgccatcaa
    10561 acatactgcc caaaaccttt gcagtatctt caatactttc ctttttacct aaatgaattt
    10621 caccagcacc catatattca ggatttgcgc ctaaatcatt gcatgcaact acaaaggctg
    10681 aacgtgttct tgttgaagat ttttcaaata aaagagctat attctttcct tttaaatatt
    10741 catgcggaat attttcttta gttccttcaa atgaagtgcg aaatcaatta gatagttaag
    10801 ctccgctgga gtatagtctt tgcattttaa taaacttctg ccttgaaaca cattttgtaa
    10861 atatttcatt ttgacgcctc ttacaaatct tcacgaacaa gtggacatga catacatctt
    10921 ggacctccac gtccacgaga aagctcactt gaatgaattt catgaactaa aatgccatgc
    10981 tttcttaaca aatcatttga tacataatta cgatcatatg taacgacttc acctggcgca
    11041 atagccaaag tattcgagcc atcattccac tgctctcttg gggctgcaat tgcatcccca
    11101 cctccggttg gaattaggtc aatctccgat aagtgcaaat aattctttaa cactttgatc
    11161 aaatcagttt ctggggtaat tttaatctca ccatgatcat cttgctctaa aacataaata
    11221 tcaatctttc ctgatttgtc taaaataaaa ggatgaacgg tacactgatc ataattaatc
    11281 attgtaaaga ctgtatccag atgcatcatg gcatgattat gtggtatttt aattgctaaa
    11341 attgtgtcat aactagaatg accaaacagg ctatgagcaa ggtcagtgat tgcggcagcg
    11401 gaagttcttt gagaaatacc gattgctaaa aacatgattg tttaaaatca gctcatcgcc
    11461 accttctaaa cgtccatgag tgtaacgatc acgccaaata ggaatattgg catttttaaa
    11521 gtcgggatga tgctttaaaa cggtttccat aaataatgac tcacgtcttc tagctctaaa
    11581 cgtcattcta ttaatagtca tgctcttttt gagctatttt taaatatgga atatcgtcaa
    11641 ttaacattcg atttaagata tccggtgaaa gattttctaa ttctcttccc ggtcgatgca
    11701 gcataactgt ttctaatttg ccaatttcgg aataaacatg aattaagtca gtcattatag
    11761 cgcctcctaa ttcaaattat gtattcgctt acaataatta tggatcaatt aggtagaagt
    11821 tacaatctta acggcttagt gaatctatta ttcttttcat taaaggcgtc accttttgat
    11881 ccttgcgcca cactaattgc aaatgcgtaa tccaattact atgtttaata ggaataagat
    11941 catcaggtac atacgtagaa gcaatagatt caggaacaag agcaatcccc atttttctct
    12001 tcgcccaagt aatcgctgtt ctagaatcat cacatttaac agcataaaac ggcttaatcc
    12061 catgatgagc aaaagtctgg ttaaaaattt cttcaaatct tcgataaata atgaggggct
    12121 gctcatttag atctttaatc cttaattccg tcttatcctt aaatttggga tcaacagtaa
    12181 ctgccatcat tctttcagta gttaaagttt ttgcatttaa gccattacga ttataaggcg
    12241 tacgcacaat tcctaaatcg attgtcttct tttccaattt atcgataatg ccaaaggtat
    12301 tatcttcata aatatcaaag ttgatttccg gataaaactt agttaaatct tgaaaacttt
    12361 tcataggaat tagtccagtt gatgatgaag ccatgcctat tgcaatcgtg cctagttcac
    12421 ctgaaacagt tttatgaacc tgatttttca ggctttctga taaagagaga atttcactag
    12481 catagctctg caaaatttgt ccagcatctg ttaattcaat tccatgagca gtacgcttaa
    12541 ataattgtgc tcctagttct atttctagtt gctttaattg ataactcagc ggcggttgtg
    12601 caatgtatag tcttttagct gctgaagtga tttgcttttc ttcagctact actaaaaagt
    12661 agcgtaattg tttaatattc attaataatc tatccttttt attttagttg tatctcttat
    12721 taaaaatttc tatatcttat attttaattt agtattttca ttcaaacaac atatgtgcta
    12781 ctttattaag gtagatttgg agggaataaa atgtctgaaa aatttcatgg cttaactcaa
    12841 gccgaagcag ataagagact taaagaaaat gggttaaacg aagtacctga acccgaatac
    12901 aactttttta aggaatttct atcaaaatta tggaatcttt ctgcctggat tctagaaggt
    12961 gccttaatcc tcgaatgtat cttaggcaaa tggattcaat ctttgttcgt cttgttgatg
    13021 cttctttttg cggcttttaa cggtgcatcc aagaaaaaac agtcacggcg ggtattaaat
    13081 accatttcac ataagctaac ccctaaggtg gctgtagaac gcgatggtaa gtggatcaaa
    13141 attgactcta aacaattagt tagaggcgac ttaatctcac ttcaacgtgg agatgtactt
    13201 gcagccgatg taaaaatggt tagcggtaag atcgcctgtg atgaaagctc aattaccggt
    13261 gaatccaagc ccgttaaaaa taacattgat gacacagctt atgctggtac tactgttgtt
    13321 gaaggcgatg gattagcaat tgttactgca actggtaaag attcaagaag tggtaagacc
    13381 attaacttga tcaacaattc agctgcacct ggtcacttgc aacaactttt aactaagatt
    13441 atttactacc tttgcctact tgacggtgta cttaccttag ttattatcat tgcttcattc
    13501 tttaagggtg gtaattttga tgcgtttatc aacatgttgc cattcttagc catgatgttc
    13561 atcgcttcaa ttccggttgc gatgccgtca acctttgcat tgtccaattc atttgaagca
    13621 acccgtttaa gtaaagaagg cgtcttaaca gctgatttaa ctggtatcca agatgcagct
    13681 aacttaaact tgcttttact tgataagacg ggaacaatca ctgaaaacaa aactgcagtt
    13741 gctagttgga gcgatttaag cgatttgcca gataaagatg tacttgcttt agccggtagt
    13801 gcaactgata agcgcaatgc aggtatcatt gatatcgcca ttgatgaata cttaaaagaa
    13861 aacaatatcc ctgtcatgga cgttgaacac tttaccccat ttacttctga cactggctat
    13921 tctatggctg aagtagatgg tcacaatgtt aagttaggtt catttaagca actttcatta
    13981 atcgataaga atgcaaatga agcagttgaa ggcatcaatt ttaaagctgg acgctcagtt
    14041 gccgtgttaa ttgatgacaa acttgcggga gtatttatct tacaagataa agtaagaaag
    14101 gactctaagg ctgctttagc agaacttaaa aaacggggcg tacgtccaat catgttaact
    14161 ggtgataatc aaagaactgc cgcagcagtc gctgaacaag ttgatttaac tggtaacgtt
    14221 atctctattc atgactttga tgaaagcacc gatattgatg aattagcagg gattgccgat
    14281 gttttacctg aagataaact taagatggtt aaattcttcc aagaaaaagg ttatatcgtt
    14341 ggtatgactg gtgatggtgt taacgactct cctgctttaa agcaagctga agttggtatt
    14401 gctgtttcta acgctgccga tgttgccaag cgttcaagta agatggtgct tctagatgat
    14461 ggcttaagct ctattgttaa aattcttgat gctggtcacc gtgtatatca acgaatgact
    14521 acttggtcac ttactaagct cgccagaacc gccgaattaa ctatgctttt aaccttcggc
    14581 tatctcttct tcaactatat tccaatggca ttaaatgcta tggttattta cacaatcatg
    14641 aataacatgg ttaccatgat gattggtacc gaccgtaccc atattactta caaaccagaa
    14701 aattggaata tgacaaggtt agccaaaatc gcattctctc ttgctgcagg ttggacagtt
    14761 atcggtatcg cttttgtcag ctacctcaat atgcatggct ggagtcacaa ttctatctct
    14821 accatggtct atgtttactt agttctaagt gcaatgttaa ttgtattaat tactagaact
    14881 cgtaaatact tctggcaaga ttacccatct aaacttgtag gtattgttca aattgccgat
    14941 gtcgcattaa cctttatttt agctttatgc ggtttagcaa tggctcaaat tagttggcaa
    15001 aacttattaa ttaccgttgt ggttgcatta attgcagcaa ttattattga tttgatttat
    15061 caaccagtaa tgaaaaacag ataattaact taaaacaaaa acactctgaa aactacatta
    15121 ctacaatgta gttttcagag tgtttttttg attaatgatt agtaactgca gtcaaggcat
    15181 tcaaagcctt aacatattca ccatcagcaa ttttgataaa tggtttttca ttaatttctt
    15241 tatggcctaa atagttaacc ttagcaccac gctttaaaaa tttgcctggg attttttcgc
    15301 cattctcatc ataaacaaag gaatgctttt tgattctatt aactactttt acagtagact
    15361 tcatatatgg caagaaggct tcttccttaa caaatctatt tttacgaatc tttacataag
    15421 tattaccatt aattactttt atggcacgta ctttgtaaag ctttcccttt cttaaatgtc
    15481 caactttaac accatgtcta ttataaacag tagcatttct agttagattt aatctcttac
    15541 cttgtctaac tggattagta acaactgcat caacgctttg tgtagttgct gcgcctaatc
    15601 caataactgc taacattata cctgcagcag aaataatttg ttttctcatc ataatccacc
    15661 cccgtagtgt ttataccatt ctccatccct tattttatca aaaattatcg aattagaagc
    15721 attttttact catctgtttt ataactattt gcttaattct gctaaaatta tttataacac
    15781 tacttaattc atgattttaa cttgggatat aatccgtagg actatcgaag tcttatggat
    15841 tatcaatatt gcgtttgctg tatggacggt ctttagaagt cgccgcagcg ttattgcaac
    15901 ttgggcatgg atgcttgtat taaccgttct gcccggtatc ggttttatcc tatatctttt
    15961 ctttggtcgt cagctttcac atgatgaaat ctttgctatt caagaagagc aaaaaaaggt
    16021 acaaagacat tatttagctg agcaacgcga catgcttaaa gagcacgatc ttctacctga
    16081 aaaagagcgt cttccacgag taaaaatgct ttcggaacta aatcttaaca acgatgatgc
    16141 gattttaact tttgataatc aggtcaaagt atttatttct ggaccagaac tttttgacca
    16201 aatgattact gatatcaaaa atgccaaaaa atctgtcagc ttagaatttt atacttttta
    16261 ttctaaccaa ttagggcatc gtgttttaaa agccttggaa gaggctgcag ctaatggtgc
    16321 taaggtaaga gtaatttatg atacctctgg atcaagaggc actaaaccaa gcttttttga
    16381 ccatttaaga gaattgggcg gcgaagctca gccatttatt tccacttcaa aaaagcactg
    16441 gtttactacc ccacgactca attaccactt acatagaaaa ttagttatta ttgaccacca
    16501 tattggctat attggcggat ttaatattgg agatcaatat gtcaataaat caccaaaatt
    16561 cggtcattgg cgggataccc atttacgtgt aattgggcaa tcaccaattc taatggaggt
    16621 ccggtttgca atggactgga acacgtcaat cagaagaaca aatttaccta aatttgaatt
    16681 aaaggaactt aaaccattta ctgtcaatcg aaaagatatc aatgataata aaaatgtcgc
    16741 tatgcaaatg gtttcctcag gacctgataa tcaacattac ggcatcagac gaggctgagg
    16801 gaattattgc aggagctaaa aaatacattt atattcaaac gccttattta attcccgaag
    16861 aatcaattct tgaagcctta attatcgctg ctaacagcgg tattgatgtt cgaattatgg
    16921 ttccttgcat gcccgatcat ccatttgttt atcgtgctac agaatactat gctaagtatt
    16981 tagtagtcca tggcgttaaa gtatacaaat ataatgatgg ttttattcat gcaaaaacta
    17041 tggttagcgg ttctaatatt tcgagaccgt aaaatagttt gtgtaaggat gaatgattcc
    17101 ttaatttaat ttc
//
