LOCUS       c00208_gnlPro..        12489 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AJFBEHNI_287.
ACCESSION   c00208_gnlPro..
VERSION     c00208_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 03:49:29
            Original ID  :: gnl|Prokka|AJFBEHNI_287
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12489
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12489
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[137:8384]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      138..8384
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..12489
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12489
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(74..199)
                     /locus_tag="ctg208_1"
                     /transl_table=11
                     /translation="MPMTPNTEQDWKAWRNLMWSEILTESVKSYMDCKCLNAISI"
     CDS             complement(138..1655)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg208_2"
                     /sec_met_domain="Fer4_7 (E-value: 1.2e-11, bitscore: 35.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.4e-11, bitscore: 33.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.5e-06, bitscore: 16.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGLYSSKTEIRHKIFTEIARMAYEGQSPEMLEELPYKIVPGEIA
                     TYRDSIFLERAVVGERLRVAMGMSLRKVTEHAPISKGVEASVIEEKYYEPPLINVIKFA
                     CNSCPEKRVMITEGCQGCLEHPCVEVCPKKAVHMEGGRSHIDEDACIKCGKCLEACPYN
                     AIIKQERPCSKACGMNAIGSDEYGRAEIDQDKCVSCGQCLVSCPFSAIVDKGQIFQTIM
                     ALKSETPVYAIVAPAIAGQFPGMENNKIRGAFQALGFTDVREVAVGADLCTVEEAKDFL
                     EEVPEKLPFMATSCCPSWSMMAKKLFPEQAKCISMALTPMVLTARLIKQKEPDCKIVFV
                     GPCAAKKLEASRKSIRSYVDFVLTFEEVAGMFDAKGVDWKDIPEGEPLFHASADGRGFA
                     VSGGVAEAVVHAVKRIDPDREVKVMNAEGLQNCKKMLQMAKIGKYNGYLLEGMACPGGC
                     VAGAGTIQTVKKAAAALEKMKKEASFTDAYDSKYRARLESLEKFDVE"
     CDS             complement(1921..2685)
                     /locus_tag="ctg208_3"
                     /transl_table=11
                     /translation="MIFTKKYRTGQIVLTACIAAVCMFSDVHGAEVAGPPAPKSKSALT
                     QKPEATPIPASTPTPEQETETDKQNPADQGTLSKPDHPDTISADKLVFIGDSRTEGLRD
                     AVNDDSIWSCLSSMGYDWMVSTGVPQVEDQIEDNTAVIILMGVNDLYHVNDYISYINSK
                     AAEWGNRGAQTYFVSVGPVQNDPYCSNAEIESFNAAMQASLSGVTYIDVYSHLVSEGFS
                     TVDGTHYPDSVSVDIYNYILDHLEEQMSGIWG"
     CDS             complement(2663..2791)
                     /locus_tag="ctg208_4"
                     /transl_table=11
                     /translation="MAGYAAWDVSMLLFTATHSRELRYVKSNVSITAEGNDIYEKI"
     CDS             complement(2764..3018)
                     /locus_tag="ctg208_5"
                     /transl_table=11
                     /translation="MRLEKVQEALKTKKIHYEYTEENGCGSIDFMFRGLRFHIWEYEDR
                     VWGAETNVFEAGRSQDIEGDYEEIISGEILSWPDMLPGM"
     CDS             complement(3537..5177)
                     /locus_tag="ctg208_6"
                     /transl_table=11
                     /translation="MKGLLKFITCGSVDDGKSTLIGHILYDAKLLYADQEKALELDSKV
                     GSRGGAIDYSLLLDGLMAEREQGITIDVAYRYFTTDNRSFIVADTPGHEEYTRNMAVGA
                     SFADLAVILVDASQGVLVQTRRHARICALMGIRYFVFAVNKMDLIEYDEKRFRDIENQI
                     AALIEELKLANVTIIPVSATEGDNVTTKSDNMPWYKGEALLSHLETVDIKEDTEKGFYM
                     PVQRVCRPNHEFRGFQGQIENGAIRAGDLVTTLPSKEEAHVKSILVGDKEVQEAVQGQP
                     VTIQLDREVDVSRGCVLTIDSGAVLTDSVEADILWMDDNALTDGKNFFVKIGTKMIPGL
                     VTKINYSVDVNTGEKKSAYTLKKNEIASCTLEFSEKIVVDEFDRHRTLGELILIDRVTN
                     MTSACGVVRKTFVSQDRSQIGKVDEQVRAGLKGQTPVVVEFPIGKEGITLDFVEQVEKG
                     LTVLGKHTYLYHPAASENYAETVRHLKAAGLVVLLVLDENTAKDETLKTLDGFYANWQI
                     DGITVKDAIDFVKKKSAFTVQSVHDGNYI"
     CDS             complement(5179..6297)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAPS_reduct"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg208_7"
                     /sec_met_domain="PAPS_reduct (E-value: 2.2e-65, bitscore:
                     209.7, seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VCLKNALRKMCVTICGRFCSDEGVVAGYDNRIRTKYTAKWGVQIA
                     GMIFQTRSSVFAQVRKDSEYKQTEEDNAMSNLSHLDALEAEAIYIMREVAAECEKPVML
                     YSIGKDSSVMLHLAMKAFYPEKPPFPFLHIDTTWKFHEMIEFRDRIAKKNGIDMLVYTN
                     EEGVKAGINPFDNGSAYTDIMKTQALKQALTKYGFTAAFGGGRRDEEKSRAKERIFSFR
                     NSAQAWDPKNQRPEMWKLYNTKIQKGESMRVFPISNWTEKDIWQYIQRENIEIVPLYFA
                     KERPVIYRDGNIIMVDDDRLKLRPGEKIENKKVRFRTLGCYPLTGGIESEADTLDEIID
                     ETLSAVSSERTSRVIDHEAAGSMERRKREGYF"
     CDS             complement(6328..6642)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg208_8"
                     /sec_met_domain="Fer4_9 (E-value: 1.7e-13, bitscore: 40.4,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.5e-09, bitscore: 26.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIRIQKSKCAGCGRCIEACPGNLIKKDKENKAFIRQVRDCWGCT
                     SCIKECRHDAIRFFLGADVGGRGASMVVSEKPDISTWTVEKPDGTKITIQVNKKDANKY
                     "
     CDS             complement(6639..8384)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 71.4; E-value:
                     2.7e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg208_9"
                     /sec_met_domain="FAD_binding_2 (E-value: 5.6e-23, bitscore:
                     71.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 9.2e-09,
                     bitscore: 25.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTERIRTDVLIIGGGTAGCFAAYVIGKKSGRKVLIAEKANIKRS
                     GCLAAGVNALNAYITEGRVPQDYVDYAKKDAHGIVREDLLLTMSERLNHVTKVMEDLGL
                     VILKDENGKYVARGNRNIKINGENMKPILAKAAAEQENVTVLNHVNITDYKTENKKVTG
                     AVGFSVNEDIFYDIDAKAVLCATGGAAGLYRPNNPGFSRHKMWYPPFNTGAGYAMGLLS
                     GAEMTTFEMRFIALRCKDTIAPTGTIAQGVGARQVNAHGDIYETKYGLTTSQRVYGTVM
                     ENREGNGPCYLRTEGISKEQEQDLYKAYLNMAPSQTLKWMEAGKGPSEENVEIEGTEPY
                     IVGGHTASGYWVDNNRATTIEGLYAAGDVAGGCPQKYVTGALAEGEIAAEAILEYLNGK
                     DDDRIAAENKEEALERGGEQELSQTAIAKKAEYESHLNASRSLMNAEQLEEAMQKIMDQ
                     YAGGIGTDYRYSGMSLAKADEKIAALLPVVDTLAATDTYELMQIYELRERLIVCQAVIA
                     HLAARKETRWHSFGENTDYPQQSEEWMKYVNSRMENGEIKIVYRDLITKENTGLNTAEK
                     GAGER"
     CDS             complement(8496..9554)
                     /locus_tag="ctg208_10"
                     /transl_table=11
                     /translation="MYVELKNINKTYGSYQASRNVNFGIEKGKLIGLLGPSGSGKTTIL
                     RMIAGLETPDSGEVIIDGKVVNDVPASQRGIGFVFQNYALFRYMTVYDNVAFGLKVQKA
                     DKKKIDARVRELIKLVGLEGLEKRYPSQLSGGQRQRVAFARALAPNPQVLLLDEPFAAI
                     DAKIRQELRSWLKEMIGKLGITSIFVTHDQDEAIEVADEIIITNAGRIEQKGTPIGVYR
                     NPETAFAASFFGQPSVLKDADDFHTFAQAEGADKIIVRPEFVKISKLDEVEKFKTSVSR
                     GVVERVSFRGDNLELQVRVNNSVVTARRSLEKADIREGETVNVFLYRIFALRGDSVQLI
                     ENEAVRDDFVII"
     CDS             complement(9556..10380)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 60.2; E-value: 7.1e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg208_11"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.5e-19, bitscore:
                     60.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNNEKTSEKITKCLLVGISVLFLAVMLLLPLITVITEALRSGWK
                     VYAAAVTDEYTIKALLLTVKATLFAVVFNTVFGVFAAWALTKFQFRGKKLLTTLIDLPV
                     TISPVIAGLIFLLIFGRQSPVYFFLMKLGMKVVFSVPGIIIATVFVTFPFISRELIPVL
                     EAEGSDEEEAAALMGAGGWTIFWKITFPHIKWALLYGVVLCTARAMGEFGAVSVLSGHL
                     RGKTNTLPLHVEILFNEFQYVPAFAVSSLLVIMAVIILVVRSLIEYKGKKEA"
     CDS             complement(10380..11216)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 82.9; E-value: 8.1e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg208_12"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.7e-26, bitscore:
                     82.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRNKSVIPGFGLSMGITISILSLVVLIPLASLVVYTAKLSFKD
                     FIETITRARVLASFYTSFVCAFAAAVINGIMGTVLAWVLVKYDFPGKRLMDGMIELPFA
                     LPTAVAGIALTSLTSDSGIVGSFFAGFGIKIAYTRIGITVAMIFVGIPFVVRSVQPVLE
                     KMDNSYSEAAGVLGAKKTTIFWKVIFPELKPAIFAGTGLAFGRCLGEYGSVVFIAGNKP
                     YYTEITPLVIMSELQEFDYSSATAIALVMLAVSFFILFLNSMIQQRNARILRGGNA"
     CDS             complement(11287..12285)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SBP_bac_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1044:Bacterial extracellular solute-binding protein
                     (Score: 56.3; E-value: 1.7e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg208_13"
                     /sec_met_domain="SBP_bac_1 (E-value: 3.6e-18, bitscore:
                     56.3, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRKLFAFGLAVVLALMPVQAFGKTVSVTNVSYDPTREMFEQYNK
                     IFEDHWKEKTGEDVEVIQSHGGSGKQALEVANGLDADVVTLALEYDIESIENAGLIKAG
                     WKDKFDNDSSPYTSTIVFLVKKGNPRDIKDWDDLTKKGVGVVTPNPKTSGGARWNYMAA
                     WAYADKKYGGDEAQMKEFIKKLYRNVVVLDSGARGATTSFVENGQGDVLVAWENEAYLS
                     MRDYPDEYEIVTPSVSILAQPSVAVVDEVVDYRNTRDVATEYLNYLYSDEAQEIAAENY
                     FRPTNEKILKKHSDTFDLNINLANISDYGGWDKVQEKHFTDGGIFDQIYER"
ORIGIN
        1 caccctgaaa aaaggcggta tcccgcctta attcagatgc tctggtaact cagttgccga
       61 gtaattcact ctgctatata ctgattgcat tcaaacactt gcaatccata taggatttca
      121 ctgattcagt cagaatctca ctccacatca aatttctcca ggctttccag tcttgctctg
      181 tatttggagt cataggcatc tgtaaacgaa gcctctttct tcattttttc gagagctgct
      241 gctgcttttt taactgtctg gatagtaccg gcacctgcta cacagccgcc cggacatgcc
      301 attccttcca aaagatatcc attatattta ccaatcttgg ccatctggag catcttctta
      361 cagttctgca gaccttctgc attcattacc tttacttccc gatcaggatc aatacgcttc
      421 accgcatgga caaccgcttc tgccacacca ccgctgactg cgaaacctct tccgtcagca
      481 ctggcatgaa acagtggttc tccttccgga atatctttcc agtccacgcc tttggcatca
      541 aacattcctg ctacttcctc gaaggtcagc acaaaatcca catagctgcg gatactctta
      601 cggctggctt ccagcttctt ggctgcacag ggacctacga aaacgatctt acaatctggt
      661 tccttctgct tgatcagcct tgcagtgaga accataggtg tcagtgccat agagatacat
      721 ttcgcctgtt ccgggaataa tttcttagcc atcatagacc aggacggaca acaggatgta
      781 gccatgaaag gaagtttctc aggaacttct tccaaaaagt cctttgcctc ctccactgtg
      841 cacagatctg caccgacggc aacctctctt acatctgtaa agccaagtgc ctgaaatgct
      901 ccccgtatct tattattctc catacccgga aactggcctg caatggcagg cgccacgatt
      961 gcatacaccg gtgtttcact ttttaatgcc ataatagtct ggaaaatctg tcctttgtct
     1021 acaatagcac tgaacggaca acttaccaga cattgtccgc aggatacaca tttatcctga
     1081 tcaatctctg ctcttccata ttcatcagag ccaatagcat tcataccaca tgcctttgaa
     1141 catggacgtt cctgtttgat gattgcatta tacggacagg cttccagaca ctttccgcat
     1201 ttgatacagg catcttcatc aatatgggat ctgccgcctt ccatatgcac tgctttcttt
     1261 ggacagactt ccacacaggg atgctccagg cacccctgac agccctctgt gatcattacc
     1321 cttttttcag ggcaggaatt acaggcaaac ttgatcacat tgataagcgg cggttcataa
     1381 tacttttcct caataacgct ggcctccaca cctttggaaa ttggcgcatg ctctgtaacc
     1441 tttctcagtg acatccccat tgcaacgcga agtctctcac caactaccgc tctttccaga
     1501 aaaatactgt cacgataagt cgcaatttca ccgggtacga tcttgtaggg aagctcttcc
     1561 agcatctccg gagactggcc ttcatatgcc atcctcgcaa tttctgtaaa aattttgtgt
     1621 ctgatttctg ttttggatga atacagtcct ctcatttttt cctcctgatt ttcgattcgg
     1681 ataactgtac ggcaatccaa tgcagggaca ccgaacaatt tccatttata atttcatcac
     1741 tgctgcaatc agcacactca tttttcctcc tgctgaactt tcagccactt cacagagaaa
     1801 cgaaattccg ctcatttccg tttccttatc tgcatatcat atcaccaaat gcttccaggc
     1861 tcaacacaac atcagaattt tcgctgaatt gtcgcccccg aagttgctgt tcatatgttg
     1921 ttatccccag attccactca tctgttcctc cagatggtcc aagatataat tataaatatc
     1981 tacggacaca ctgtccggat agtgggttcc gtctacggtg gaaaatccct cagataccag
     2041 atgggaatat acgtctatgt aggtaactcc actcaggctt gcctgcattg ccgcgttaaa
     2101 actttcaatc tccgcattac tgcaataggg atcattctgc accggaccta cagacacgaa
     2161 ataagtctgc gctcctctgt tcccccattc agcagctttg gaattaatat aactgatgta
     2221 gtcattgaca tgataaagat cattaacacc catcaggata ataaccgctg tattgtcctc
     2281 aatctgatct tctacctgcg gcactcctgt agataccatc cagtcatatc ccatagaaga
     2341 aagacaggac caaatgctgt catcgtttac cgcatccctc aatccctctg ttctggaatc
     2401 tccgataaat accagtttat ctgcggagat agtgtccgga tggtctggct tgcttaaagt
     2461 tccctggtct gccggattct gtttatctgt ctcagtttcc tgctccggtg ttggagtaga
     2521 tgcaggtatt ggtgttgctt caggtttttg tgtcagtgcc gatttggatt tcggtgccgg
     2581 cggacctgcc acttctgccc catggacatc tgaaaacata cagacagctg caatacatgc
     2641 ggttaatacg atttgtccgg ttctatattt tttcgtaaat atcattccct tctgcagtaa
     2701 tacttacgtt acttttcaca tatctcaact ccctggagtg tgttgctgtg aacagtaaca
     2761 tacttacatc ccaggcagca tatccggcca tgagaggatt tctccggaaa taatttcctc
     2821 gtaatctcct tcaatatcct ggcttctgcc tgcttcgaac acgtttgtct ccgctcccca
     2881 gacacgatct tcatattccc atatatggaa tctcagaccg cgaaacataa agtcgatgct
     2941 tccgcatcca ttttcctctg tatattcata atgaattttc tttgttttta acgcttcctg
     3001 tactttttcc aaacgcataa aatacctcct gattatctgt acagtacctt ctgtaatata
     3061 atacagataa ctttcactgt aaaaaaatgt tctcgtgtac acccatcaaa agtcaaacag
     3121 atattcgcaa tccgcttcgc tacacagctc tacatatgct cttaatcctg acgccattat
     3181 acaaaacgaa ttatatcata ctctgctgca taatatgtaa tctgaatgcc acttcacaat
     3241 tgcccattct acattctgat cgatattcac tcatctttat ttctgtcttt tcttcgttgg
     3301 tatcgccagg atgatgattg tagcaattac aaacaaagtt ccaagcatca tctctttttt
     3361 tggttttgtt tactttcatt gttcgtttgc atatttctgt tatctttcct gtctgtatta
     3421 ttatggattc tgaatatttg aaaataagta taatccgctg taacgacact tgtcaagaaa
     3481 acaaaatacc gcagagactt tctttgtctc tgcggcgatt tatagccctg ttataatcag
     3541 atataatttc catcatgtac actctgcact gtaaatgcag atttcttttt cacgaaatca
     3601 atcgcatctt tcacagtgat tccgtcaatc tgccagttcg catagaaacc atccagagtc
     3661 tttaatgtct cgtcttttgc tgtattttca tcaagaacaa gaagtacgac cagacctgct
     3721 gccttaagat ggcggacagt ttctgcatag ttttcactcg ctgccggatg atacagatag
     3781 gtatgttttc caagtacagt cagtcccttt tctacctgct ctacaaaatc aagagtgatt
     3841 ccttctttac cgatcgggaa ttccactact accggtgtct gacctttcag tcctgcacga
     3901 acctgctcgt ccacttttcc gatctgggat ctatcctgag aaacaaaggt ttttctcaca
     3961 acaccgcatg cagaagtcat atttgtgaca cgatctatca ggatcagctc acccagtgtt
     4021 ctgtgcctgt caaattcgtc tacaacgatc ttctctgaga attccagagt acaggaagca
     4081 atctcatttt tctttaaggt atatgcgctt ttcttttcac ctgtattaac atccacagaa
     4141 taattgatct ttgtaaccag gccggggatc atctttgtac cgatttttac aaagaagttc
     4201 ttgccatccg taagagcatt gtcatccatc cagaggatat ctgcttccac agagtctgta
     4261 agaactgcgc cggaatcaat ggtaagtaca catccgcggg aaacatctac ttctctgtca
     4321 agctggatgg taacaggctg tccctgtacc gcttcctgaa cttctttatc gccaacaaga
     4381 atactcttta catgagcttc ttctttactg ggaagagtag tcacaaggtc gcctgccctg
     4441 atggcaccat tttcaatctg tccctggaat ccgcgaaact catgatttgg tctgcagact
     4501 ctctgtacag gcatatagaa gcccttctct gtatcttcct taatgtctac ggtttccaga
     4561 tgggaaagaa gcgcctcacc tttataccat ggcatattgt cagatttggt tgtaacgtta
     4621 tcaccttctg tggcagatac cggaataata gttacattgg caagtttcag ttcttctatc
     4681 agtgctgcga tctgattctc aatgtcgcgg aaacgttttt catcatattc aataagatcc
     4741 attttgttta ctgcaaatac aaagtaacgg attcccatca atgcgcagat tcttgcatga
     4801 cgtcttgtct gtaccagtac tccctgtgaa gcatccacca ggataactgc cagatctgca
     4861 aaggacgcac ccactgccat gtttcttgta tattcttcat gtccgggtgt atctgcaaca
     4921 atgaagcttc tgttatctgt tgtaaaataa cggtatgcaa catcaatggt aattccctgt
     4981 tcacgctctg ccatcagacc gtccagaaga agagaataat caatggcacc gcctctgctt
     5041 cctactttgg aatccagctc cagagctttc tcctgatctg catagagaag ctttgcatca
     5101 taaagaatat gtccgatcag agtggatttt ccatcatcca cacttccgca tgtaataaat
     5161 ttcaataatc ctttcattct agaaataccc ctctctcttt cttctctcca tgctgcctgc
     5221 tgcctcgtgg tcgatcaccc tgctggtacg ttcagaagaa acagcactta acgtctcatc
     5281 aataatctca tccagagtat ctgcttcaga ttcaatacct ccagtaagcg gatagcaccc
     5341 aagagtacgg aatctgactt ttttgttttc aatcttttca cccggacgga gttttaatct
     5401 gtcatcatcc accataatga tatttccgtc tctgtagatg accggtcttt ctttcgcaaa
     5461 atataacggt acaatttcga tattttcacg ctgaatgtac tgccagatat ccttttctgt
     5521 ccagttggaa attgggaata ctcgcatact ctctcccttc tggatcttag tgttataaag
     5581 cttccacatc tccggtctct ggtttttcgg atcccatgcc tgagctgaat tgcggaaaga
     5641 aaagattctt tcttttgctc tggatttctc ctcgtcacgg cggccgcctc caaatgccgc
     5701 tgtaaatcca tatttggtca gagcctgttt taacgcctgt gttttcatga tatctgtata
     5761 tgcagaacca ttgtcaaatg ggttgattcc tgcctttaca ccctcttcat tggtgtaaac
     5821 cagcatatca attccgtttt tctttgcgat tctgtcgcgg aattcgatca tctcatggaa
     5881 tttccatgta gtatcaatgt gaaggaacgg gaatggaggt ttctccgggt aaaatgcctt
     5941 catcgccaga tggagcataa cggagctgtc ctttcctata gaatagagca taaccggctt
     6001 ttcacactcg gctgctactt ctcgcataat ataaatcgcc tctgcctcaa gcgcatcaag
     6061 atgagataag ttactcattg cattatcctc ctctgtttgt ttatactcgg aatcttttcg
     6121 tacttgagca aatacactag agcgtgtctg aaaaatcatt cccgcaatct gcacgcccca
     6181 ctttgcggta tattttgtcc gaattcggtt gtcgtagccc gctacgacgc cctcatccga
     6241 acaaaatctc ccacaaattg tgacgcacat cttgcgtaaa gcatttttca aacacactct
     6301 aaagactctg agaatacata cttatgttta atatttatta gcgtctttct tattaacctg
     6361 aatagtgatc ttagtgccat ccggcttctc cactgtccat gtggaaatat ccggtttctc
     6421 tgatacaacc atacttgcac ctctgcctcc cacatcagct ccaaggaaaa agcggatggc
     6481 atcatgcctg cattccttaa tacaggaagt acatccccag cagtctctta cctgacggat
     6541 aaaggctttg ttctctttat cctttttgat cagatttccg ggacaggctt cgatacatct
     6601 gccgcatcct gcacatttac ttttctgaat ccgaatgctc atctctcacc tgctcctttc
     6661 tctgctgtat tcaaacctgt attttccttt gtgatcaggt cacgatatac gatcttaatc
     6721 tcgccgtttt ccatacggga gtttacatat ttcatccact cttcgctctg ctgcgggtag
     6781 tctgtattct ctccgaaact atgccatctg gtttcctttc tggctgccaa atgtgcgatc
     6841 actgcctgac acacgatcag tcgttcgcga agttcataaa tctgcatcag ttcataagta
     6901 tctgttgctg ccagagtgtc aactactggc aacaatgctg cgatcttttc atctgccttt
     6961 gcaagactca tcccgctgta tctgtagtct gtaccgattc ctcctgcgta ctgatccatg
     7021 atcttctgca tggcttcctc aagctgctct gcattcatca aagaacggga agcattcaaa
     7081 tgtgattcgt attctgcctt cttagctatt gcagtttgag acagctcctg ttctccgcca
     7141 cgctctaaag cctcttcctt attttccgct gcgatccggt catcatcttt gccattcaga
     7201 tattccaaaa tcgcctctgc tgcgatctca ccttctgcca gtgcgccggt tacatatttc
     7261 tgcggacatc ctcctgctac gtctccggct gcatataaac cttcaatagt tgtagctctg
     7321 ttattatcta cccagtaacc gctggctgta tgtccgccta caatatatgg ttctgtgccc
     7381 tcaatctcta cattctcttc ggatggtcct tttccggctt ccatccattt cagagtctgg
     7441 gacggtgcca tattcaggta agctttataa aggtcctgct cctgttcttt ggaaatgcct
     7501 tccgttctga gataacatgg accgtttcct tctctgttct ccatgactgt accgtaaact
     7561 cgctgggaag ttgtcagacc atattttgtt tcataaatat caccatgtgc attgacctgt
     7621 ctggccccaa caccctgagc aatagttcct gtaggagcaa tcgtgtcctt acatctcaat
     7681 gcaatgaaac gcatctcaaa ggttgtcatc tccgcaccgg aaagaagtcc cattgcatat
     7741 cctgcacctg tgttaaacgg aggataccac atcttatgtc tggaaaatcc cggattattc
     7801 ggtctgtaaa gtcccgctgc accacctgtg gcacaaagaa ctgctttcgc atcaatgtca
     7861 tagaaaatat cctcattaac gctaaatcca actgcgcctg tgactttttt gttttctgtt
     7921 ttataatctg taatatttac atgattgaga accgtaacat tctcctgttc agctgccgcc
     7981 tttgcaagga ttggcttcat attttcgcca ttgatcttga tgtttcggtt tcctctggca
     8041 acatattttc cgttttcgtc cttcaggatg accagcccca gatcttccat cacctttgtc
     8101 acatgattca gtctctctga catggtaaga agaaggtctt ctcttacgat tccatgggca
     8161 tcctttttgg cataatccac ataatcctgc ggcactctgc cttctgtaat atatgcgttc
     8221 aatgcattca cgcccgccgc cagacatccg cttcgcttaa tattcgcttt ctctgcgatc
     8281 agaacttttc tgccgctttt tttgccgatc acataggctg caaagcatcc tgccgtaccg
     8341 ccaccgatga tcagcacatc tgtcctgatt ctctctgttc tcattctctc ttaccctttc
     8401 ctccatacca gtgtgccaac aagttgattt cccgatcagt cttgcgtctg aatttcttat
     8461 ttcttcattg tcgtcagtcg ccgcagccac cgctgtcaga taattacaaa gtcatccctt
     8521 acagcctcat tttcgatcag ctgtacactg tcacctctca gtgcaaaaat cctgtaaagg
     8581 aatacattca cagtctcacc ttcccggata tctgctttct ccagacttct tctggcagtt
     8641 actacggaat tgttgactct cacctgaagt tccagattat ctcccctgaa agaaacccgt
     8701 tcaaccactc cccgggatac ggaagttttg aacttctcca cctcatccag tttggagatt
     8761 tttacaaatt ccgggcggac aatgatcttg tctgctcctt ctgcctgagc aaaggtatgg
     8821 aaatcatccg catctttcaa cacagatggc tgtccgaaga aggacgctgc aaaagctgtc
     8881 tcaggatttc tataaacccc tataggagtt cctttctgtt cgatccgtcc tgcattagtg
     8941 ataataatct catctgctac ttcaatggcc tcatcctgat catgagtaac gaaaatactg
     9001 gtaattccca gcttcccgat catctctttt aaccagcttc gcagttcctg acggattttt
     9061 gcatcaatgg ctgcaaaggg ctcatccaga agcagcacct ggggatttgg agcaagggct
     9121 ctggcaaatg ccaccctttg cctctgaccg ccggataact ggcttggata tcttttttcc
     9181 agtccttcca gccccaccag tttgatcaac tctctgactc tggcatcaat tttcttctta
     9241 tcagccttct gaaccttcaa accaaatgca acgttgtcat aaactgtcat atagcgaaac
     9301 aacgcataat tctgaaatac aaatccaatc ccacgctgac tggccggaac atcatttacc
     9361 acttttccat caataatgac ctctccgctg tccggggttt ccagacctgc gatcattcga
     9421 agaatagttg tttttccgct tccgcttggt cccaacagac caatcagttt acctttctca
     9481 attccgaaat tcacattcct tgatgcctgg taagaaccat atgtcttatt gatatttttt
     9541 aactctacat acatatcagg cttccttctt tcctttatat tcaatcaggc ttctgactac
     9601 cagaatgata accgccatga tcacaagcag tgaagatacg gcaaacgccg gaacatactg
     9661 aaactcatta aacaaaatct ctacatgaag aggaagtgta ttggtctttc ctcttaaatg
     9721 tccggaaagt acagataccg ctccaaactc tcccattgct cttgccgtac agagcacaac
     9781 tccatacagt aatgcccatt tgatatgagg gaatgtgatc ttccagaaaa tggtccatcc
     9841 acctgctccc atcagggctg ccgcttcctc ctcatcgctt ccttctgctt ccagaaccgg
     9901 aatcagttct ctggaaataa aaggaaaggt tacaaataca gttgcaataa tgattcccgg
     9961 tacagagaat acaactttca tccctaactt catgagaaaa aagtaaacag gactctgtcg
    10021 tccgaaaatc agaagaaaga tcaaacctgc aataacaggg gaaatagtaa ccggaagatc
    10081 gatcagggta gtgagaagct ttttacccct gaactgaaac ttcgtcagtg cccaggctgc
    10141 aaaaacacca aaaacagtgt taaaaacaac tgcaaagagt gttgccttca ctgtaagaag
    10201 aagtgctttg atggtgtact catctgtcac tgcagctgca tagaccttcc atccgctccg
    10261 caatgcttct gtgatcacag tgatcagagg aagaaggagc atgactgcca gaaacagaac
    10321 actgatcccg acaagcagac attttgtaat tttctccgaa gtcttttcat tgttgtccat
    10381 caggcatttc ctcctcttaa aattcttgca tttctctgct gtatcatact gttaaggaac
    10441 agaataaaaa atgaaactgc caacatcaca agtgcgattg ccgttgcact tgaataatca
    10501 aattcctgaa gctctgacat aataaccagc ggtgtgattt ctgtataata gggtttattt
    10561 cctgcgataa atacaacact tccatattca cccagacatc ttccgaacgc aagtccggtc
    10621 cctgcaaaga ttgcgggctt cagttccgga aaaatgacct tccagaagat agttgttttc
    10681 tttgctccca acactcctgc tgcctcgctg taagaattat ccatcttttc cagaaccggc
    10741 tgtacacttc gcacaacgaa cggtatccct acaaatatca tggccactgt aatgccgatt
    10801 cttgtgtatg caatcttgat accgaatcct gcaaaaaagc tgcctacaat tccggaatct
    10861 gaggtcaggg atgtcagtgc aatacctgct accgctgtgg gaagagcaaa gggaagttcg
    10921 atcatcccat ccataagtct cttgcccgga aaatcatatt tcacaagcac ccacgcaaga
    10981 acagttccca taattccatt tattactgct gctgcaaaag cacatacaaa actggtataa
    11041 aaggatgcca gcactctggc tcttgtgatg gtttcgataa aatctttaaa actcagcttc
    11101 gctgtgtaga ccaccagact tgccagggga atcagaacta ccagactcaa tatggaaatg
    11161 gtaattccca tggagagccc aaaccctgga atcaccgatt tatttctttt tttcataatc
    11221 aattaccacc tctcctgtct catatattct gtctgtgctt atgctcttgc ttcatcttgt
    11281 cttcctttat ctctcataaa tctgatcgaa aattccgcca tctgtgaaat gtttctcctg
    11341 cactttatcc catccgccat aatcactgat atttgccaga tttatattca gatcaaacgt
    11401 atcactgtgc ttcttcagga ttttctcatt agtggggcgg aaataattct ctgctgcgat
    11461 ctcctgtgct tcgtcggaat acaaataatt caaatactca gttgccacat ctcttgtatt
    11521 tctgtaatcc accacttcat ctaccaccgc cacagaaggc tgtgccagaa tacttacgct
    11581 tggagtaaca atctcatact catccggata atcccgcatg gatagataag cttcattttc
    11641 ccacgcaacc agcacatctc cttgtccgtt ctccacgaaa gaggtcgttg cgcctcttgc
    11701 gcctgagtca agaaccacca cattccggta aagtttcttg ataaattcct tcatctgtgc
    11761 ttcatcgcca ccatactttt tatctgcgta agcccacgct gccatgtagt tccatctggc
    11821 accgccggag gttttcggat ttggtgttac tactcccact ccttttttcg tcagatcgtc
    11881 ccagtctttg atatccctgg gatttccttt cttcaccaga aatacgatag tggatgtata
    11941 aggagaactg tcattgtcaa atttatcttt ccatcctgcc ttgatcagcc ctgcgttttc
    12001 aatagactca atatcatatt ccagtgccag ggttaccaca tctgcatcca gaccattggc
    12061 tacctcaagt gcctgtttcc ctgaaccgcc atgggactgt atcacttcca catcttcccc
    12121 cgtcttctcc ttccagtggt cttcaaatat tttattatac tgttcaaaca tctctctggt
    12181 aggatcatag gaaacattgg tgacagacac cgtttttcca aaagcctgta ccggcatcag
    12241 ggccagtaca actgcaagac caaaggcaaa taattttctg atcatgtttc atctccttta
    12301 aagtaccagt agttttttgc attctctact tttcatagtt attcgatatg ttttatatga
    12361 tattacaaga aatgacagaa tttgtcaata gtgtattaaa ataagtacaa tttatgttgt
    12421 gtagataaga acacaatcac gaccaccggc ttagccggtg gtttgctttg accctataag
    12481 ggtctatta
//
