LOCUS       gnlProkkaJDFNHJKK_110  13887 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JDFNHJKK_110.
ACCESSION   gnlProkkaJDFNHJKK_110
VERSION     gnlProkkaJDFNHJKK_110
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:20:54
            Original ID  :: gnl|Prokka|JDFNHJKK_110
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13887
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13887
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9569:12263]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9570..12263
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..13887
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13887
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             121..1089
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 214.8; E-value: 3.4e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_1"
                     /transl_table=11
                     /translation="MKLGILGAGGIASTMAKTVAGMKDVEAYAVAARDLERARVFAQKY
                     EVKKAYGSYEEMLADDEVGLVYIATPHSHHYLHAKMCLEAGKHVLCEKAFTVNAEQAQK
                     LFDLAKEKKLLITEAIWTRYMPSRKMINDIIESGVIGEVTAVTANLSYTVSHVERIRKP
                     ELAGGALLDVGVYPINFASMVLGDKVKDVKATAIFQNGVDILDSIAMVFEGDRMATLQC
                     GAREISDRMGSIFGTRGYMQVQNINNPEKITVFDTEHKEVASYVVPEQISGYEYEVESC
                     MKAIHEGKTECPEMPHAETIRIMKIMDDIRKSWNYEIPCIE"
     CDS             1284..3965
                     /locus_tag="ctg78_2"
                     /transl_table=11
                     /translation="MKSNYKIFTAVFLSAIMTAAAPLTVCGAEVFSAGESFSDGTGSIP
                     AILTDMVLPDGEIGTEYQVQLEADTDVNWSLEEGSELPAGFTLSSGGVISGMPQEEGSF
                     SFTVQADNGIGVSSQELSLYVAQREQEPVIKQYELTSGTALIDLGIHAEGEQSRKRLFL
                     YNAGTDSLHLSDFPQSRYFDFSYAPIFDTNTDEEMQPGSCAAVDIDDKKNLPAGNYEET
                     VTFETKEGASCKVTLKVIVGASSEKDYELSIETGTEEEFTESDFYDPEFRVEKYVVVRN
                     SGKKETRIRIDTSGLKNFEVDDQMAKWTEDYEEQDSKKLLKPGETLYFYILPKQEYGIY
                     DETFAFLADDGSRYPLHVTMNREKNPTEKKQLEITEKSAGGFPTMQWGYKTLPEAKTYI
                     LKNVTDTDMKLSFNRSKECSVLLSGNAYLAPGESTELRLWPKLGLSVGKYSFQVTVTAK
                     TVAGEHLTTQNLYNSFIVGDRTYQGLADAVAPVTGITNGAEKTADALHLPKSLEVYGAE
                     VNGEKTTFSASVKWDVENCAYDPKSKAAQSFLVNGSLELNEDENNEGLDTAVQIMVQVD
                     AYQTLNRPVIDTRWTRVITNYAMLYLRDLSNEADGYQFVTAKSQKDLKKGNYTAQTKIA
                     NSELNQYPELKYIPEGTHSLYCRAYKENSSHVMEYGEWSDGVPVTVKVKTPDAPVVQKV
                     QVKKNDVRIVLNSKGEEPDGYDVVAARSKNGKEPSDYIKVKSGYSGSSKELILRGVPAG
                     TWYIGVHAYKYLNGSNTKVLSKWAEVRKVTVKTSLVTGKPAVKSAKVSRQGTKRNVTVT
                     FTAPKSCDGTDWVLAKKVSKSDDGSYTGVSSYAYTKKNQTKTTVVFKSVKPGVYYLAGR
                     AYVKGYAKSYTKWSKIKKIVVK"
     CDS             4247..5005
                     /locus_tag="ctg78_3"
                     /transl_table=11
                     /translation="MKQKKIVIIMAGILAAAAAMTGCAEQNKTATQVDYTQNSQGKSEQ
                     TKQKTAEKSQPDKKQVNKSTFDGKENSNQTADKKTKVFASSNNAGDVQNSGNGTDGTAG
                     TDTDDSQTTGVDTSTSEDNGSTGNDGTQSDQRADQAMIYDSEGNGRLISEADDGNWYDS
                     DGNYYGSWEDIEDAMVNENGVTDQDGNKYYWTAPHDASEEVTDPYDLYSWDPGTNSYIP
                     FQAAESDCSPIGRGNGWYYYDEDSGEYVPW"
     CDS             complement(5147..6040)
                     /locus_tag="ctg78_4"
                     /transl_table=11
                     /translation="MTKTEKAVTWAIEIANDPAHGYDQDNRWGPDYDCSSLVISAWQQA
                     GVPVKTKGATYTGNMKSVFLSCGFKDVTSKVNLSTGSGMKRGDVLLNIASHTVMHIGNG
                     QVVSASKNENNGYHGGKPGDQSGKEIKLQNYYNFPWDCVLRYTKDSSTTDPDPEPQPTA
                     GNAKIRKGQGYANKFANAGISITGKRDAATKKAGVKVLQTALNRDYGAGLDVDGIWGTN
                     TDNALGQHYVKNGETQYMVTAAEILLLLRAYDPNGVEIPGTFGSGLLSAVKAFQKAQGL
                     TVSGTCDRNTFLKLIS"
     CDS             complement(6228..6563)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.1; E-value: 6e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg78_5"
                     /transl_table=11
                     /translation="MKNNTIGKRIAEARINKHITQEHLEELSGLSVSTISRIETGKYMP
                     TIENLLKLSEILDVGLDYFLYDLLPHNKDIQSPAIQDAISIMNQMGERQTEYIVKILKI
                     YQASHQD"
     CDS             6682..7236
                     /locus_tag="ctg78_6"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTIREILKKTGKTREDFFPKGYLLGKRIKLTRSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKGDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             7242..7949
                     /locus_tag="ctg78_7"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKDITEQYFAEKNVDCTVTTYQNVEWFLL
                     GLNEEKFDMYILDIRMPGENGIEAAREIRRLYPDPVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKEKLPQAYDALLPGIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTVEKELNTKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGV"
     CDS             7953..9434
                     /locus_tag="ctg78_8"
                     /transl_table=11
                     /translation="MLKVLLYGLATFMETGIGVWIFSQTFSERRILEKKYYVLEWLLYS
                     LIFFGIYNFSVSLWQIDKKIEKYVIKVICIYIIGLIAGIIYDIFFVKKKEMVLRRILYI
                     GMIFWLTAQYWAGYQSLLMIILGSGIIVLYVFCYFDCTFKQAYVWNFFYAVNIGLIKEA
                     YVVYAGVFNHKQWDDFYSYPRGHTYQEVIFWILGCLFIFWIIKFILSVNSIKGILRTRL
                     KELFIIGLLEYVLLIVSIIYKFGTIKKENFVMTACLLAVSNIALIGVYVKFQKKTLEMR
                     NQILDMRCKLMEEEYEELRMSYDRYRCLVHDEKHLLLYIKECLENGELDSCITFLNHYK
                     RESIRYSGVAWTGIPEINFMLNIKVRKMEEKNIFFKVDSKIEKIPMKDIDFVVLLGNLL
                     DNAIEAAEKCEEGKGKITCIFRNINDMFIFKVKNTSIYKPYEKNTKFYTSKKEKDEHGW
                     GIESVKQIVRKYNGEIDFKYDKDFFEVEIIISDNT"
     CDS             9451..9579
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_9"
                     /transl_table=11
                     /translation="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYGTIVCC"
     CDS_motif       9451..9561
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /locus_tag="ctg78_9_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9562..9579
                     /prepeptide="core"
                     /locus_tag="ctg78_9_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="519.7"
                     /monoisotopic_mass="519.2"
                     /core_sequence="TIVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /leader_location="[9450:9561](+)"
     CDS             9570..12263
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     763.1; E-value: 7.2e-231)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_10"
                     /sec_met_domain="DUF4135 (E-value: 6.7e-94, bitscore:
                     304.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.4e-52, bitscore:
                     168.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLKLDYLCRKNRTMFLKILILDVHRQKNFGNLKGSTPKEQYDYY
                     EKKYLNNATYVKSLLQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRK
                     FSGTVGIYMSKGDIHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGIS
                     CRTVQYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAH
                     GEYPVIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNR
                     GVLISAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYT
                     ECIIRGFCRAYMVAMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRE
                     CRKALLNVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLP
                     CTPYESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIY
                     SQIRKIVHRICSRAIIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLH
                     DFEEKNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLT
                     GKRVWMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADME
                     KDLWKKGQETGNGYGWRLKGTDGPLAGMSHGNSGFLMAYAALYECNHKAEYADKIQLLL
                     RYEDSLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLN
                     AADSLFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAK
                     ISGTEYLNLAFMNGISGTGMALMEIL"
     CDS             complement(12316..12840)
                     /locus_tag="ctg78_11"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILRYISENK"
     CDS             13141..13371
                     /locus_tag="ctg78_12"
                     /transl_table=11
                     /translation="METTVMNVAVSQGIWAVLAVFLLIYIVKSNEQRDTKQEEREKNYQ
                     TVIESLTEKFQILNQVQSDLKEIKDNLFNKN"
ORIGIN
        1 ggagagtaca agaacttgtg agtagataga tatttatatc atcaaaagca tactcgttga
       61 agtaggaatg aaacatagaa gtttataact ttttataagt tttcagtaac ggacagtaaa
      121 atgaagttag gtattctggg agcaggaggc attgcttcta ctatggcgaa aacagtggca
      181 ggaatgaaag atgtggaggc gtatgcggtt gctgctcgtg atctggaacg tgcccgggta
      241 tttgcacaga aatatgaagt aaaaaaagca tatggatcct atgaggaaat gctggcagat
      301 gatgaggttg gactggttta tatcgcaact cctcattcac accattatct gcatgcgaaa
      361 atgtgtctgg aagcgggaaa gcatgtgctt tgtgaaaagg catttactgt aaatgcagag
      421 caggcacaaa aattatttga ccttgcaaaa gagaaaaagc ttctgatcac agaagcaatc
      481 tggacaagat atatgccgtc cagaaagatg atcaacgata ttattgaaag tggtgtgatc
      541 ggagaagtta cggcagttac cgcgaatctc agctatacag taagtcatgt ggaacgtatc
      601 cgtaaaccgg agcttgcagg aggtgctctt ctggatgtag gcgtatatcc gatcaatttt
      661 gcctccatgg tgcttggcga taaggtaaag gatgtaaagg ctactgcaat ctttcagaat
      721 ggagtggata ttctggacag cattgccatg gtgtttgagg gagaccgcat ggcaaccctt
      781 cagtgtggag caagagaaat ctcagacaga atgggaagta ttttcggaac cagaggatat
      841 atgcaggtgc agaatatcaa taatccggaa aagattacag tgtttgatac cgaacataaa
      901 gaagtggctt cttatgttgt gccggaacag atctcaggat atgaatatga ggtagaatcc
      961 tgcatgaaag caattcatga gggaaaaacg gagtgtccgg aaatgcctca tgcggaaaca
     1021 ataaggatca tgaaaatcat ggacgacatc cgtaaatcct ggaattatga gattccctgt
     1081 atcgaataaa aagtgtggaa taatcttata aaaaagacca gtaatgtttt tgacatatac
     1141 ccgaaacatt actggctttt ctgatattca tgaccattat acaacatgtc attccgtaat
     1201 tacagaaaca ttcccgtcca gtggtatatt aatattaatt aggtaaattg atacttttat
     1261 attttattat ctggaggaga agaatgaaaa gtaattacaa aatttttaca gcagtttttt
     1321 tatcggcaat tatgacagca gcagctccgt taacagtatg tggggcggaa gttttttcgg
     1381 cgggagaatc tttcagtgat ggaacgggga gtattcctgc catattgaca gatatggttc
     1441 tgccggatgg agagattgga acggaatatc aggtacagct tgaagctgat acagatgtga
     1501 actggagtct ggaagaggga agtgagcttc cggcgggatt tacgttgtct tccgggggag
     1561 tgatcagtgg aatgccacag gaggaaggga gtttcagctt tactgtacag gcggacaatg
     1621 gtattggagt ttcttcacag gaactgagcc tttatgttgc acagcgtgag caggaacctg
     1681 ttataaagca gtatgagctg acatcaggta ctgctttgat cgatctggga attcatgcag
     1741 agggagaaca gtcacgtaag cggttatttc tttataatgc aggaacagat tcgcttcatc
     1801 tctctgattt tccgcagagc agatattttg atttttccta cgcaccgatt ttcgatacaa
     1861 atacggatga agaaatgcag cccggaagtt gtgcggctgt ggacattgat gataagaaga
     1921 atctgcctgc cggaaattat gaagagacag tgacatttga gacaaaagag ggtgcttcct
     1981 gtaaggttac tctgaaagta attgtgggag cttcctctga aaaagattat gagctgagta
     2041 tagaaacagg tacagaagaa gaatttacag aaagcgattt ctatgacccg gaatttcgtg
     2101 tggagaagta tgtagtggtc agaaattcag gaaaaaagga aaccagaata cggatagata
     2161 cttctggtct taagaatttt gaagtggatg accagatggc aaagtggaca gaagattatg
     2221 aggaacagga ttccaaaaag ctgctgaaac cgggagaaac gctttatttt tatatattgc
     2281 cgaagcagga atacggaatt tatgatgaaa cgtttgcatt tctcgcagat gacggaagca
     2341 gatatcctct tcatgttaca atgaacagag agaagaatcc gacagaaaag aagcagctgg
     2401 aaattactga aaagtctgcc gggggttttc cgacaatgca gtggggctat aagacacttc
     2461 cggaagcaaa gacatatatt ctgaaaaatg ttactgatac agatatgaag ctgtctttta
     2521 accgtagtaa agaatgtagt gtgttattat ctggaaatgc ttatctggca cctggggaga
     2581 gcacagaact gagactctgg cccaaactgg ggctttcggt gggaaaatat agttttcagg
     2641 tgactgtgac tgcgaaaaca gtggcaggag aacacctgac aacgcagaat ctgtataatt
     2701 cttttattgt aggagaccgg acttatcagg gactggcaga tgctgttgcg cctgtgaccg
     2761 gaattaccaa tggtgcagaa aaaactgctg atgctttgca tctgccgaag tcgctggaag
     2821 tctatggcgc cgaggtgaat ggagagaaaa caacattttc tgcgtctgtg aagtgggatg
     2881 tggagaattg tgcttatgat ccgaaaagca aggcagctca aagttttctg gtcaacggat
     2941 ctctggaact gaatgaggat gaaaataatg aagggctgga cactgccgta cagataatgg
     3001 tacaggtgga tgcttatcag acattaaaca gaccagttat tgatacgcgg tggaccagag
     3061 tgatcacaaa ttatgcaatg ctttatctga gagatctttc caatgaagcg gacggctatc
     3121 agtttgtgac agcgaaatct cagaaggatc tgaaaaaagg gaattatact gcgcagacaa
     3181 aaattgcaaa ttctgaactg aatcaatatc ctgagctgaa gtatattccg gagggaacac
     3241 atagtcttta ttgcagggca tacaaagaga acagcagcca tgttatggaa tatggggaat
     3301 ggtcagacgg ggttccggtt acggtaaagg taaagactcc ggacgcacct gtggttcaga
     3361 aggtgcaggt gaagaaaaat gatgtcagaa tagtacttaa cagcaagggt gaggaaccgg
     3421 acggttacga tgttgttgct gccagaagta agaacggaaa agaaccatcg gattatataa
     3481 aggtaaagag tgggtattcc ggaagcagta aagagcttat cttacggggt gtaccggcag
     3541 gaacgtggta tattggcgta catgcttata aatatctgaa tgggagcaat accaaagtgc
     3601 tcagtaaatg ggcagaggtc aggaaggtaa ctgtaaaaac aagccttgta acaggaaaac
     3661 ctgctgttaa atcagctaag gtttccagac agggaacaaa aagaaatgta acggtgacgt
     3721 ttactgctcc aaagtcctgt gatggaacag actgggtact ggcaaagaaa gtttccaaat
     3781 ctgatgacgg cagctataca ggtgtaagca gttatgctta tacaaagaaa aatcagacaa
     3841 aaaccacggt ggtctttaaa agtgtgaagc ccggagtcta ctaccttgca ggacgtgcct
     3901 atgtaaaagg ctatgcaaaa agttatacga aatggtcgaa aataaagaaa atagttgtga
     3961 aataagcact gctgtcattt gtttcacaga gatttcactt ttaagaagaa aaatccccct
     4021 tttaccaggc gtttatacct gctttttcct gtaatactca aagtttacgg tactgccact
     4081 tattatactc aaatcttgtc tgaatttgga gataaataat gtccttttta tgacagataa
     4141 gggacatatg aggcatcgaa gcctgtgaag tatgtcataa tgaacaggga aagcacatta
     4201 tgataaaggc agtgacattt ttaacaaatg tagaaaggac aacaaaatga agcagaaaaa
     4261 gattgtaatt attatggcag ggattttagc agcagcggct gctatgacgg gctgcgcgga
     4321 acagaataaa acagcgacac aggttgatta tacgcagaac tcacagggga aatccgaaca
     4381 gacaaaacaa aaaacagcag aaaaatctca gccggataaa aaacaggtaa ataaaagtac
     4441 attcgatgga aaagaaaatt caaatcagac tgcggataag aagacgaaag tatttgcctc
     4501 atccaataat gcgggcgatg tacagaattc agggaatgga acagacggta ctgcgggaac
     4561 tgatacagat gattcccaga ccacaggggt ggacacttct acatctgaag ataatggttc
     4621 aacaggtaat gatggtactc aatctgacca gagggcagat caggcaatga tatatgacag
     4681 tgagggaaat ggaaggctga tttctgaagc tgatgatgga aactggtatg acagtgacgg
     4741 aaattactat ggaagctggg aagatattga agatgctatg gtaaatgaaa atggtgtcac
     4801 agatcaggat ggcaataaat attactggac agcacctcac gatgcatcag aagaggtcac
     4861 agatccgtat gacctgtatt cctgggatcc gggaaccaat tcctatatac cgtttcaggc
     4921 tgcggaatct gactgtagtc ctataggcag aggaaacggc tggtattact atgatgaaga
     4981 cagcggcgaa tatgttccgt ggtaaaaata agaaaacaaa agaaacagtt ttgaaatcat
     5041 tttgatgggt ttcaaaactg tttcttttta tatacaagaa atagtgaagg ggcatatccg
     5101 gcagaatcag tgaaaagaat tctgccggat gtttatctgg taaagatcag ctgatcagtt
     5161 tcaggaaagt atttctgtca caggttccgg aaaccgttaa gccctgtgcc ttctggaatg
     5221 cctttacagc agagagaagt cctgagccaa aggtaccggg aatctctaca ccgtttggat
     5281 cataagcacg taaaagaagg agaatctcag cggcagttac catatattgt gtttcaccat
     5341 tttttacata atgctgtcca agagcattgt ctgtgtttgt tccccagata ccgtctacat
     5401 ccagaccggc accataatcc ctgttcagag ctgtctgaag aactttaacg cctgcttttt
     5461 tggtagcagc gtctcttttt ccggtaatag agattcctgc attggcgaac ttattggcat
     5521 aaccctgacc tttgcggatt tttgcatttc ctgcagttgg ctgaggttca ggatcaggat
     5581 cagtagttga agaatcttta gtataacgga gaacacaatc ccaagggaaa ttgtaataat
     5641 tctgaagttt gatctctttt ccactctgat ctccgggttt accaccatga tatccattat
     5701 tttcattttt gctggcagat accacctgac cattgccaat gtgcattact gtatgacttg
     5761 cgatgtttaa taatacgtca ccacgtttca tgccacttcc tgtgctgaga ttaactttgg
     5821 aagtcacatc cttaaagccg caggacagaa agacggattt catatttcct gtataagtgg
     5881 ctccttttgt ttttacagga acaccagcct gctgccatgc ggagattacc agtgaagaac
     5941 aatcgtagtc cggtccccat ctgttatcct gatcatatcc gtgtgccgga tcgtttgcga
     6001 tttcaattgc ccatgttact gctttttctg tttttgtcat tttttcatcc tcctgaaatt
     6061 tgattattta tttgctcacc ggtgatacat cttataaaga gtgagaaaag ggaaaaatgt
     6121 aaacatgaaa cagaaaaaaa taaaaagcat ttcctgattg ttgcttcgag gtcagaaaaa
     6181 tgcttttcga ggacaaaaac acgaaaattg tcgaattgta attatattta atcctgatga
     6241 gaggcctggt atattttcag tatttttaca atgtattcag tctggcgttc acccatttga
     6301 ttcatgattg aaatcgcatc ctgaatagcc gggctttgaa tatctttatt atgaggaagc
     6361 agatcataaa gaaaatagtc aagtcccaca tcaagaattt cagaaagctt aaggagattt
     6421 tcgatagtag gcatatactt acctgtttca atccggctga tcgtacttac agataaacca
     6481 cttaattctt ccaggtgttc ctgggtaata tgtttattga tccgagcttc tgcaattctt
     6541 tttccgatag tattgttttt cataaataaa aatcctttcc tttgataaag tttatcagac
     6601 ggaattaaat atgtataagg atataaatga caagcgacta atcaaatttg atatgtttta
     6661 tgacaggagg aatataggaa tatggacgaa tatacaaagg atttgtatac catgatgttt
     6721 tctttgcaga ctttgcaaaa tcagggaatt acaatcagag aaactgtata taaaagtctg
     6781 gacaaattac tgttatggaa taaagaatct gaaaacagta aatatctcga attagcgttg
     6841 cttcatatgc aggcttatgc taatatggga tttgctttag atgaagaaaa taagacaata
     6901 cgtgagatat taaaaaagac aggaaagacc agagaagact ttttcccgaa aggatatctt
     6961 cttggaaaga gaattaaact gaccaggtca caggttcgtg gtatgattgg aagatggaga
     7021 ccttccagag acagtccgat gacaatcgga gaactggtgg atgatatcat cagaaaggta
     7081 aaaaaccatg aggaaggcag atacatttat cagtatcaca gaactgatgt gacaaccaaa
     7141 ggggatatcg aggtttatga gctggtcatc aataaggatg aaagttattt ttatgatgtg
     7201 aagaaattca gattttatac attcatggag gaataattgc tatgataaga ataatgattc
     7261 tggatgatga cgaaatgtat ctgaaaaaag aaaaggatat cacagaacag tattttgcag
     7321 agaaaaacgt agattgcacg gtaacgacat accagaatgt ggaatggttt ctgctgggat
     7381 tgaatgaaga aaaattcgat atgtatattc tggatatccg gatgcctgga gaaaacggaa
     7441 tagaggcagc gagggaaatt cgcagacttt atccggatcc ggttattata tttattacaa
     7501 attttgtgga ttatgcaata gaagcatatg aggtaaacac ctatcgttat atccccaaag
     7561 agtgtctgaa ggaaaaactt ccgcaggctt atgatgcgct tcttcctgga attatggaga
     7621 aagaagagcg gtactatatc ataaataaaa gaaatgaagt tgaaaaactg gcatattctg
     7681 atattttcta tatgaaaaaa gaaggaaaat atgtgatttt tgtgcacagg cgtggggaag
     7741 taaagatcag agcaagtctg tcaacagtag aaaaagaact gaatacaaaa gaatttatta
     7801 tatctgacag aggatatctt gcaaacatcc aacatgtgat gaagatgaaa ggaagggatc
     7861 tttatatgcg ggacggtaat attattacag ttggcagaga aagattcaaa ggtgtcagag
     7921 aagcaattct gaattactgg ggggtatgaa gaatgctgaa agttttattg tatggactgg
     7981 caacgtttat ggagacaggg ataggtgtct ggatatttag ccagacgttt tctgaacgaa
     8041 gaatattaga aaaaaaatat tatgttctag aatggctgtt gtattctttg attttttttg
     8101 gaatttataa tttttctgtt tcattatggc agattgataa aaaaatagaa aaatatgtca
     8161 taaaagttat ttgtatatac ataattggat taattgcagg aattatatat gatatttttt
     8221 ttgtaaagaa aaaggagatg gtcttaagaa gaatattata tatcggcatg atattttggt
     8281 taactgctca gtattgggct ggatatcaat cgttgttaat gattattctt gggagtggaa
     8341 taattgtatt atatgttttt tgctactttg attgcacatt taaacaggca tatgtttgga
     8401 attttttcta tgcagttaat ataggattga taaaagaggc ttatgttgta tatgcagggg
     8461 tgtttaacca taaacagtgg gatgattttt attcatatcc gagaggacat acatatcagg
     8521 aagttatatt ttggatttta ggctgtttat tcatattttg gataattaaa tttattttgt
     8581 cagtaaacag tataaaagga atattgcgta cacgtctgaa ggaacttttt attattggat
     8641 tgttagagta tgttttatta atagttagca tcatatacaa atttggtacg attaaaaagg
     8701 aaaattttgt aatgaccgca tgtttattag cagttagtaa tatagcattg attggtgtat
     8761 atgttaagtt tcaaaaaaag accctagaaa tgagaaatca gattttagat atgagatgca
     8821 aattaatgga agaagaatat gaagaattga gaatgtcata tgaccggtat cggtgtttgg
     8881 tgcacgatga aaaacatttg cttttatata taaaagaatg cctggaaaat ggagaactgg
     8941 attcatgtat cacttttttg aatcattaca agagagaaag cattagatat agtggagtag
     9001 cgtggacagg aattccagaa ataaatttta tgttgaatat aaaagtgcga aaaatggaag
     9061 aaaagaatat tttttttaaa gtagattcaa aaatagaaaa aattccgatg aaagacatag
     9121 attttgttgt actcctagga aatcttttgg ataatgcaat agaagctgct gaaaagtgtg
     9181 aagagggaaa aggtaaaatt acgtgtattt ttcgaaatat taatgatatg tttattttta
     9241 aagtaaagaa tacaagcata tataaacctt atgaaaaaaa cactaaattt tatacaagta
     9301 aaaaagagaa agatgagcac ggatggggga ttgaaagtgt caaacaaatt gtaagaaagt
     9361 ataatggtga aatagatttt aaatatgata aagatttttt tgaagtagaa ataataatta
     9421 gcgataatac ataatgggag agtgacggtt atgaacgaaa tgaatgataa aataatagga
     9481 aatgtggaaa aagaattaga tgaaatagag ataatagata cggaaagtat agaagagaaa
     9541 ttgtctttta ttgtatatgg aactatagtg tgttgctgaa attggattat ttatgcagaa
     9601 aaaatcgaac tatgtttctt aaaatattaa tcttagatgt acatcggcag aaaaattttg
     9661 gaaatctaaa aggaagtacg ccaaaagaac aatatgatta ttatgaaaaa aaatatctta
     9721 acaatgcaac atatgtaaaa tctttactgc aggaatatcc cgagttaaaa cgtctgcttg
     9781 aattgaaaaa taactctatc cagagagcag aatgtgaaat caggaaatct ctttatgcag
     9841 aaaaagaaca gatacaaaaa atattctgtg atggaagaaa gttttccggg actgtgggaa
     9901 tttacatgtc gaaaggcgat atacacagag gaggacgaag tgtggcgaag gtagaattgg
     9961 ataatggaac aattctgtac tataagccac atagtcttga taagaatata aaatatcagg
    10021 aactttataa ctatttatgc agaaaaacag gaatttcctg caggacggta caatatttat
    10081 ctcatgattc ctatggatgg gaagaaaaaa ttgagaatat tccctgtaaa aacgaaagtg
    10141 aggtggagca ttattatttc agaatgggca tacatctgtt tttgggatat gccctcggag
    10201 caacagatct tcatggtgaa aatattattg cacatggaga atatcctgtg attatcgata
    10261 tggagacata tccgggatat ttaaaacaac aatcagagaa agacggaagt agtgtagaag
    10321 aaaaaataaa caaaagtaca gagataaaat tggcaaattc ggttatacat acaggaatgc
    10381 ttcctgttct cacatggggc agaggaaaca gaggagttct tataagtgca atgggaacag
    10441 aggaaaagat aaaaacaccg tttaaacttc ctgtggtaaa ggatgataaa acatctgata
    10501 tccacataga atatgaacct gtggaaatgc agataaagga atgcattgta agactaaatg
    10561 atcaggttat caatgcggca gattatacgg aatgcattat cagaggattt tgcagagcgt
    10621 acatggtggc aatggcagat aagaaagtgg aggtgatgtt gtccggcttt tttgacggac
    10681 gttccagagt tgtactgcgg catacccaac agtatgcaat gtatcttatg gcttcgtttc
    10741 atccggatta tatgaagtca agagaatgca ggaaagctct tttgaatgtg attcacaaag
    10801 agggggaatc ttcttttatg aaagagattc atgattatga aattgacagc cttctggaaa
    10861 tggatatacc ctgctttgag attgatgcga acagcagatc tgtttatgat ggaaatggcg
    10921 gagaacataa agaatatctg ccctgtactc cttatgagtc atggcgaatg catatgaagc
    10981 agatgagtta ctctgatatg gaatgtcagt gtgattatat caggctgtcc atggaaatgc
    11041 tgaaggcatc tgatggaaag aaaaagatgt ttccgaccag gataaaggga tatgacacag
    11101 ataaagagcg caaaatatac agtcagatca gaaagatagt tcatcgaatc tgcagcagag
    11161 caattatccg ggaacagagc gccggctggg cgggtctgca attctgggat aatggtcact
    11221 ggaatctcag atcaggtgga atatatttat atgatggaat atccgggata gtcttgtttc
    11281 ttgcaaaata tcttcatgat tttgaagaaa agaatgcaag tgcagaagaa atttatcatc
    11341 ttgctgtttt gagattgaaa gcttatacag atgaaataca caaaaaacag atttatgata
    11401 aaaatcttct gacaggtatt gtaaatggag aaagctcggt ggtatatacc tatctttatc
    11461 tgtttaaact tacaggaaaa agagtgtgga tgatttatgc ggaaaagcat ttcagcatta
    11521 ttgagagggt atggaaagaa gattcacaac tggattatct gagcggaaat gccggagcta
    11581 ttgtagtggc agtgatgtta tataaagaaa ccggaaatct gaaatattat gaaatagcgg
    11641 cagatatgga aaaagatttg tggaagaaag gacaggaaac cggaaatgga tacggatgga
    11701 gattaaaagg aacagacgga ccgctggctg gaatgtctca tggcaacagt ggatttctga
    11761 tggcttatgc agcgttgtat gaatgtaatc ataaagcgga atatgctgat aaaatacagc
    11821 ttttgctgag atatgaggat tctctgtact cagagaaagc cggaaactgg aaggatttac
    11881 gagagagttc aggggaaagc ttcatgaatg catggtgcca tggggcgccg ggaatcctgc
    11941 tttcacgaat gaaactggaa gagctgtttc ctgaggatat gcagattaaa aaagacaggt
    12001 taaatgctgc agactctttg ttttatggag aacaggatga aaaaatttgt ctgtgtcatg
    12061 ggatgtccgg gaatttactt attatgaaga agtaccttcg aaaatatggt aataaaaaaa
    12121 tgaaggagca atatgaggcg ttatgtgact gccttttatt tcaactggat cacccggcaa
    12181 aaatatctgg gacagaatat ctgaatctgg cttttatgaa tggcatttcc ggtacgggaa
    12241 tggcattaat ggaaatttta tgaaaactaa gggaacacct gcagactgta aatttatggt
    12301 cagcaggtgt ttcttttatt tgttttcgga aatatatctg agaattagtt tcttcttcat
    12361 ccgattgacg tactggcggg acagcttcag tttccgggca atctgggcat cgcttttatc
    12421 ctgataaaag tacatggaca gaatttttct ctggacactg tccgaagggt aagagttgat
    12481 atatgcggtt acatcataat aggtgtcatc aaaactgtcg ggagcctgta atgaaacaga
    12541 acaagaatca aaatcatctt tttcaggttc ggaaagacaa ctgcggcaaa gggaacgata
    12601 tctgttttcg acagaggtct gcatgtatct gatacattca ccttctgagg atgaagaact
    12661 taaatatggc aatgtcttta acaaagtaag atacaattcc tgtgtggaat cttcgcgttc
    12721 catgcagtga atccgggatg catatccttt cacaagcggt tccatacgtt tgagaatttc
    12781 actgtctgaa tctgggatac cattttgata attttggata agttctgtca gtgttttcat
    12841 aggtatctac ctccttttta ggggaagtag taagaaaact gctgatcaga aactaaaaaa
    12901 gaaaaaaatt tgtgagttta caaatggaag agaaaaaact ctttattaag tgaggttgca
    12961 aatttagatc agcgatagga gaagaaatac atggtaaaaa gagatttgca aaataattgt
    13021 agagaataga aatatgcttt aaattaaaac ggtaataata agattagaaa agacttttag
    13081 tagacaaaac atagaaaaag tttgcataat aaaagaagat taaggaagga ggcagaaacc
    13141 atggaaacaa cggttatgaa tgtggcagtt tcacagggaa tctgggctgt gcttgcggtt
    13201 tttcttctga tttacattgt gaaatcaaat gaacagaggg atacaaagca ggaagaacga
    13261 gagaaaaatt accagacggt gattgagagt ttaactgaga aatttcagat tctgaatcag
    13321 gttcaaagcg atctgaaaga gattaaggat aatcttttta acaaaaatta aatagggaaa
    13381 agaaaaaagc cttttctgca ggatatattt ttccagcgga gagggcttct gtcattttag
    13441 gtaagaaaat aggttaattt gagaaaaata tgtttactaa aatggtagat gaatataagc
    13501 ataacattcg tgtccattag aatactttta atcccagatt tacagatgtt cgtatagtaa
    13561 atggtatatt atgataataa aacctgactt ttgggtagtg taaaatagat taaaaaaaat
    13621 ggccgcaatc caagtgttta tgcgagggtg taaaaattct tgtgtctatg gaaagtaaat
    13681 ctttctgata agaaatagat atgtaaaatt ttgctgtcga attaatgatt atgcggctgt
    13741 cgaatatatc tttgtactta cagtattgcc atgtaggaaa attatataca tcattttcga
    13801 tttttttgca tgacaagtaa ggcatcatga ttaccttaac ttccaaaaat gagtagccct
    13861 aacgaaaata aaattttaaa aaagccc
//
