LOCUS       gnlProkkaNEMGPHMC_42    7484 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NEMGPHMC_42.
ACCESSION   gnlProkkaNEMGPHMC_42
VERSION     gnlProkkaNEMGPHMC_42
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 01:28:50
            Original ID  :: gnl|Prokka|NEMGPHMC_42
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7484
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7484
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3675:4409]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3676..4409
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..7484
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7484
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             255..1967
                     /locus_tag="ctg42_1"
                     /transl_table=11
                     /translation="MEFSAVNTIWVLVGAALVFFMQAGFAMVETGFTRAKNAGNIIMKN
                     LMDFCIGTPVFWLVGFGLMFGAGNGFIGKIGGIATEAHYGSGMLPDGVPFWAFLIFQTV
                     FCATSATIVSGAMAERTKFLSYCVYSLMISLVVYPVSGHWIWGGGFISQMGFHDFAGSC
                     AVHMVGGVAALIGAIILGPRIGKYTKDGKSKAIPGHNLTVGALGVFILWFCWFGFNGAS
                     TVSMEGDAIVSAGKIFVTTNLAAAVATVTVMIITWVRYKKPDVSMSLNGSLAGLVAITA
                     GCDTVSPTSAAIIGIASGFIVVFGIEFIDKVLKIDDPVGAVGVHGLNGAFGTLAVGLFS
                     DGSGTDWKGLLTGGGFHGFGVQFTGMIITIAWVVVTMTIIFQVIKHTIGLRVSAEEEIA
                     GLDSKEHGLASAYDGFAMAGVPTPMGTSIKAPVVTARPSAPAESVPELPKEGVHKLTKV
                     VIITRQNKLDEFMQAMNEIGVTGITITNVLGCGVQKGAPSYYRGVEMEMNLLPKVKIEI
                     VVSLVPVQKVIETAKAVLHTGQIGDGKVFVYDIENVVKIRTGEEGYLALQDTK"
     CDS             complement(2150..2296)
                     /locus_tag="ctg42_2"
                     /transl_table=11
                     /translation="MEKRKYKVVIAQSGKLDVKEKRNISFSNLNTGSMQRIFPKRLKSG
                     SCT"
     CDS             complement(2306..2512)
                     /locus_tag="ctg42_3"
                     /transl_table=11
                     /translation="MIKIETKVLFQERVMVMALAQATKSHEPTYTINDAMDVLLSRLDE
                     AIDDMESDRVQIVEEAWAEIDAI"
     CDS             complement(2718..3041)
                     /locus_tag="ctg42_4"
                     /transl_table=11
                     /translation="MKYMRKNSFVVCLVISAILLTSSFAMPVLAAENTGIETSSVTRSV
                     PGYYKCTGSDVNIRSGPGTQYTIVGTLNYGTKVYVYSISNGWAKISLGGIYRYVSADYL
                     REL"
     CDS             complement(3078..3461)
                     /locus_tag="ctg42_5"
                     /transl_table=11
                     /translation="MTHKKEVVFSLLFVIMVLCTGCSDKDNGDTSKNNRTSGESFVQEE
                     TIESTDNTDNADGSSAPTPELKTPRTKKELEDALGTVNESGKWTPPAGSHIDPKTGNIL
                     NKDGVVVGTTQEPYSKARPGSQG"
     CDS             complement(3676..4260)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_6"
                     /sec_met_domain="AgrB (E-value: 7.1e-37, bitscore: 115.9,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKCTDTVVNWMIRCNAINEADKELYKYALYSFFLLVSPLILAGV
                     IGFGLGSVKHGVALIFPFVVLRKFSGGYHAKNLHTCILGSGFLLFLCIMLSMHVQCDLK
                     LAIATVIASVSLITFSPIDSENRRLDTNEKRTYKKTTVFFVILFGLLDIALFLLGKYIY
                     TICFSVGILLTAGLQVPCIVKKMCKSTKNRL"
     CDS             complement(4260..4409)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_7"
                     /sec_met_domain="TIGR04223 (E-value: 6.2e-15, bitscore:
                     44.5, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKEVTKSVAKGMKAALDVVLRTEANTASCLIMYQPKAPKELMNY
                     RRNK"
     CDS             4705..5034
                     /locus_tag="ctg42_8"
                     /transl_table=11
                     /translation="MGNRIKIRRKELRIKQAELAERLNISNNHMSSIENGRQKPSLDIF
                     IQICNLLNVTPDYLLLGSMHAYNIPQDIIDKLRLSNQSDIELAGDFIELLVKRNNKATH
                     NEPKL"
     CDS             5126..5833
                     /locus_tag="ctg42_9"
                     /transl_table=11
                     /translation="MRILICDDDTLIIEQLKKYIESYFESNHLKCPELVSFTSGEALLT
                     DKGEKDIVFLDIEMPGMNGIYVGNELKKANRNVIVFVVTSYSEYLDEAMRFHVFRYLSK
                     PLDKQRFFRNLKDALAYYNSITLKIPVETKQAVYSFPASQIIAIEAQGRKVIVHTARQD
                     FDSIHNMNYWLEKLPQNSFFQTHRSFIVNFEHIVDFDHSTVHLSNPQITAYLTRRKYSS
                     FRNAYLLYLESMR"
     CDS             5840..7138
                     /locus_tag="ctg42_10"
                     /transl_table=11
                     /translation="MEYIILLIFSFFTEAVILWQYAASLFSPSHSGKKRLTLLSVLYVL
                     LFFLSLLGQTWLNIISFFVINTVFLYIMFNLKLLLALFHSAILTAIMGISELAVLGMIS
                     RFFPHFLLEASVGLVFYTVFSKITFFAVVYLLSWLFKGNKAAQEPYGHSEILLMFIPLS
                     SILMMFTLLSIGETTAYAPPVDFLVTICAVFLLLVNLLVFGINQYNTKRSQEYADLQLL
                     LQKESDSVEYYEMMLAQNENQSILIHDIKKHLQSIRLLNEKNDSDKINDYIQQLMESSD
                     LKETTKLCDHEMLNSILCRYQRHCNDKHIIFHTDIRSGTVQHIYPRDLTSLFCNLLENA
                     VESAENIPDSFIELTVQKKENSPFLIIILINSCQNTPVYNPEGLPISHKSDNGRHGFGI
                     KSIKKVVKQYHGNLQMYYDNDSGTFHTILTLKQ"
ORIGIN
        1 cctcgcttgc tgccggaggt tcttcgtcta tcacacgata ttttgatgtt cccctgtttt
       61 acatataatt ttgattttaa actgcattgc atacagtcat acgaaatgtc ttttctatta
      121 catcagttat gcaatacact ataaatatgg attttatatt cgcaaaagcg cgatgaactg
      181 gctacatttc caggcatcgc gctttttgca ttttataaaa tatgaggaaa tttttatgag
      241 ggaggaatat tattatggaa ttttccgcag taaacacaat atgggtgctg gtcggcgccg
      301 cgctggtctt ctttatgcag gccggattcg caatggtaga aacaggcttc acacgagcca
      361 aaaacgcagg taacattatt atgaaaaacc tgatggactt ctgtatcgga accccggtct
      421 tctggctggt cggctttggt ctgatgttcg gtgcaggtaa tggatttatc ggaaagatcg
      481 gtggtattgc aacagaagca cactatggtt caggaatgct tcctgacgga gttcccttct
      541 gggcattctt aatcttccag acagtattct gtgcaacatc cgcaacaatt gtttccggtg
      601 caatggcaga acgtaccaag ttcctttcct attgtgtcta cagccttatg atcagtcttg
      661 ttgtatatcc ggtatccgga cactggatct ggggcggtgg atttatcagc cagatgggat
      721 tccacgattt cgcaggttcc tgtgcagtac atatggtagg tggtgtggca gctctgatcg
      781 gtgccatcat ccttggacct cgtatcggta aatatacaaa ggacggcaaa tcaaaagcta
      841 tccctggaca caaccttaca gttggtgctt taggtgtatt tatcctctgg ttctgctggt
      901 tcggatttaa cggtgcttcc acagtcagta tggaaggcga tgcaatcgta agtgcaggta
      961 aaatctttgt tactactaac cttgcagcag ctgttgcaac tgtaactgtt atgatcatca
     1021 catgggtacg ttacaaaaaa ccggatgttt ccatgtctct gaacggttct cttgcaggac
     1081 ttgtagcaat tacggcagga tgcgacacag tttctcctac atccgcagca atcatcggta
     1141 ttgcttccgg ttttatcgta gtatttggta ttgaatttat tgataaggtt ctgaaaatcg
     1201 atgatcctgt tggtgctgtc ggtgttcatg gtttaaacgg tgccttcggt acccttgcag
     1261 ttggtctctt ctccgacggt tcaggcacag actggaaagg acttcttaca ggcggcggct
     1321 tccacggatt tggtgttcag ttcacaggta tgatcatcac aatcgcatgg gttgttgtta
     1381 ctatgacaat tatcttccag gtaatcaaac atacaatcgg acttcgtgtt tcagctgaag
     1441 aagagatcgc aggtcttgac tccaaagaac atggtcttgc aagtgcttat gacggtttcg
     1501 caatggctgg tgttccgact cctatgggaa cttccataaa agctcctgtt gtcacagcca
     1561 gaccttctgc tcctgctgaa tcagttcctg aacttccgaa agaaggcgtt cataagctta
     1621 caaaagttgt tatcatcacc cgtcagaata agcttgatga atttatgcag gcaatgaatg
     1681 agatcggtgt tacaggtatc actattacga acgttctcgg atgcggtgta cagaaaggtg
     1741 ctccatccta ctatcgtggt gttgagatgg aaatgaatct tcttcctaag gtcaaaattg
     1801 agattgttgt aagtctcgta cctgtacaga aagttatcga aactgccaag gcagtcctcc
     1861 ataccggtca gattggtgat ggtaaagtat ttgtatatga cattgaaaat gtcgttaaga
     1921 tccgtacagg cgaagaaggt tatctcgcac tgcaggatac aaagtaaatt atttatcaac
     1981 aatcaggtaa tattaataag agacatcagc gtattgattg ctggtgtctc ttattttaat
     2041 ctttctttct aacaattcca atggcgttaa aaaacaggca gtatatttca tgtaaatatc
     2101 atagccacga tatcggaagc ctattgtatt atatctggta ggaagtgtgt caagtgcaag
     2161 aaccgctttt taatcttttg ggaaaaatcc tctgcatact cccggtattt aaattgctga
     2221 aggatatatt tcttttttcc ttcacatcca gcttgccgct ctgggcaatt acaactttgt
     2281 attttctttt ttccatccgt accccttata ttgcatcaat ttctgcccat gcttcttcca
     2341 ctatctgcac tctgtcactt tccatatcat caatggcttc atccagcctt gacaaaagaa
     2401 catccattgc atcattgatt gtataagttg gttcatggga ttttgttgcc tgtgccaatg
     2461 ccataaccat caccctttct tgaaatagca cttttgtttc tatttttatc ataccacgaa
     2521 ccaccggaaa tatctatata ttttaaattt gtctttataa cccaaacaca gaatactgtt
     2581 tttgggacgt tttttagaat ttgtccattt gtagtttcaa ttaaaaaagt aaataaaagt
     2641 gctgccgcac caaacttttc agtgcggcag cccatacagc tatttaccta tgcctcgttt
     2701 atattaaatg tttttcctta aagctcccga aggtaatcgg cactaacata acggtaaatg
     2761 ccgccaagag aaattttggc ccacccatta ctgatagaat atacatatac ttttgtgcca
     2821 taattcaatg tgcctactat tgtatattgt gttccagggc ctgatctgat atttacatcc
     2881 gaccctgtgc acttgtaata tcccggtacg cttctcgtga cagagcttgt ttcaattcct
     2941 gtattttccg cagcaagcac cggcattgca aatgaacttg tcaaaagaat tgcacttatg
     3001 accaaacaca ctacaaatga gttttttctc atatacttca taatcttttc ctcccataat
     3061 ttttttacac catatcatca tccttgagaa cctggacgtg ctttactata aggttcctgc
     3121 gtagttccaa ccacgacccc atctttattc agtatattac ctgttttggg atctatatga
     3181 gaaccggctg gtggcgtcca ttttcccgac tcattcactg taccaagcgc atcttccaat
     3241 tcctttttcg ttcggggcgt tttcagttct ggcgttggtg ccgagctgcc gtctgcattg
     3301 tctgtattgt cagtactctc aatagtttct tcttgaacaa atgattctcc tgaagtcctg
     3361 ttatttttag acgtatctcc attatcttta tcactgcagc ctgtacataa caccattatt
     3421 acaaacaaca agctaaaaac aacttctttc ttatgtgtca ttttaatctt ttacctccat
     3481 tatgcccgtt taactactcc gaaccgaact actcaattta aagtgataga attctatcat
     3541 tgtcccattg gaatccactc cctttcaatg aacaaactga attaactgta aataaagaac
     3601 tttgatcaaa tcaatgacaa actttattat ctttattttt gccatgattt caaccccttt
     3661 tgcaccaaac gacatttaca gtctgttttt ggtcgattta cacattttct ttacgataca
     3721 aggtacttgt aagcctgctg tcagtaatat cccaacagaa aaacagattg tatagatgta
     3781 ctttcccagc aaaaataaag ctatatctaa cagcccaaac agtatcacga agaacactgt
     3841 tgttttttta tatgtccttt tctcgttagt atcaagtctt ctgttttcac tgtctattgg
     3901 actaaatgta atcaggctca cagacgcaat aactgtagct attgccaact tcaaatcaca
     3961 ttgcacatgc attgataaca ttatgcacag aaacaataga aaaccagatc caagaataca
     4021 agtgtgcaaa ttttttgcat gataaccacc actaaatttt ctcagaacca caaacggaaa
     4081 aataagagca actccgtgtt ttacgcttcc caagccaaag ccaataactc ctgcaaggat
     4141 aagtggtgat accaatagaa aaaaactata taatgcatac ttgtaaagtt ccttatccgc
     4201 ctcgtttatc gcattacacc ggatcatcca atttactact gtatctgtac atttttccat
     4261 tacttgtttc tcctgtagtt cattaattct ttcggtgcct taggctgata catgataaga
     4321 caagaagctg tgttagcttc tgtccgtaac acaacatcta atgctgcttt cattcctttt
     4381 gcaaccgatt tagttacctc tttcttcata atgacctctc tcctttccac taaaatttgt
     4441 cattgatttt cacataagca atcatatacc actttaatca aataaacgac ccctttggaa
     4501 tgaacggaat gattctttac aatattggat aatttccctc ttttctacga aaaataatat
     4561 gtgatacaga attatttata tataaatatc agtttgttta atatattgca gaatagttct
     4621 ttgttacatt cttcttttta tttagttcta ttggtaaaat tctactgaaa gaaggtggga
     4681 taaatagaat ttcaatatga aggtatggga aaccgcatca aaatacgcag aaaagaatta
     4741 cggataaaac aggcagaact tgccgaaaga ttaaatatat ccaataacca tatgtcatca
     4801 atcgaaaacg gaaggcaaaa accaagtctg gatattttca ttcagatttg taatttactc
     4861 aatgttacac ctgactacct tctgctcggc agtatgcacg cttataatat tccacaggat
     4921 attattgata aactacggtt atctaatcaa tccgacatag agcttgccgg agactttatc
     4981 gaactgcttg taaaacgaaa taacaaagca acacataatg aaccaaaatt gtaattaaat
     5041 tgtcttttca tacgcatttt ttgcatttgg aaattctatg tgataagatg tacacataca
     5101 tctatttaga aagtcaggtg aaaaaatgcg tattttaatt tgtgatgatg acactctgat
     5161 cattgaacaa ttgaagaagt atatcgaatc ctactttgag tccaaccatt taaaatgtcc
     5221 tgaattagtt tcttttacca gtggtgaagc tttgttaact gacaaaggtg aaaaggatat
     5281 tgtttttctg gatatcgaaa tgcctggcat gaatggaatc tatgttggga atgaattaaa
     5341 aaaagcaaat agaaatgtga tcgtttttgt tgtcacctct tattctgaat atttggatga
     5401 agcaatgcgt tttcatgtat tccgttacct ttccaaacct ctagataagc agcgtttttt
     5461 ccgaaatctg aaggatgcct tagcttatta caattccatt acactcaaaa ttcctgtgga
     5521 aacaaaacag gcggtatatt cgtttcctgc ttcgcagatt attgccatag aagctcaggg
     5581 gcgaaaagta attgtacata ctgcccgtca ggactttgac tctattcata atatgaatta
     5641 ctggttggaa aagcttcccc aaaacagttt ttttcagaca caccggagct ttattgttaa
     5701 cttcgaacat attgtggact ttgatcactc caccgtacat ttatcaaatc ctcagattac
     5761 cgcttacctg acacgcagga aatacagttc cttcagaaat gcatatctac tatatctgga
     5821 aagcatgagg tgaaaataaa tggaatatat tattttactt atttttagtt tttttacaga
     5881 agcggttatc ttatggcagt acgccgccag ccttttttcc ccttctcata gcggtaaaaa
     5941 gagactgact ctattaagtg ttctttatgt actgttgttt tttctttccc tgcttgggca
     6001 aacatggctg aatattatca gtttttttgt gataaacact gttttcctct atataatgtt
     6061 taacctcaag ttattattgg cactcttcca ttccgctata cttacagcga ttatgggaat
     6121 atctgaactt gcagttttgg ggatgatatc aagattcttt ccccattttc tcttagaagc
     6181 aagtgtcgga cttgtttttt ataccgtatt tagcaaaatt accttttttg cagtcgttta
     6241 cttgttaagt tggctcttca aggggaacaa agcagctcaa gaaccgtacg gtcactccga
     6301 aattctcttg atgttcatcc cgctttcctc tattcttatg atgtttactc ttctttctat
     6361 tggtgaaaca accgcatatg ccccaccggt tgattttcta gtaacaatct gtgccgtttt
     6421 tctgttgctg gtcaacctac ttgtatttgg aatcaaccaa tataacacaa aaagatcaca
     6481 ggaatatgcc gatttgcagt tactgctcca gaaagaatcc gattctgttg aatactatga
     6541 aatgatgctt gcacaaaacg agaaccagag cattttgatc cacgatataa agaaacatct
     6601 tcaatcaatc agattactga acgaaaaaaa tgattccgat aaaataaatg actatataca
     6661 acaactcatg gaatcttccg acttaaagga aaccacaaaa ctctgtgatc atgaaatgct
     6721 aaactccatt ctgtgccgct atcagcgcca ctgcaatgat aagcacatta tttttcacac
     6781 tgacatcaga agcggcacgg tacaacatat atatccgcgc gatttgactt ctttattctg
     6841 taacttattg gagaatgcag tggaatcagc agagaatatt ccagactctt ttattgagct
     6901 caccgtacaa aagaaagaaa attcaccctt tcttattatc atactcatca actcctgcca
     6961 aaatacccct gtatataatc cagagggact tcctatatcc cataaatcag acaatggcag
     7021 acatggattc ggaatcaaaa gcattaaaaa agtcgtaaaa cagtaccatg gaaatttgca
     7081 aatgtattat gataatgatt ccggtacctt ccatacaatc ctaaccttaa agcagtaaat
     7141 attaaaatct ggcaatcgca attttatacg attgcctttt tacatatttc agcatgcatt
     7201 gatgttgttt tatatcacta taaatgagca agttcgtgat tttgcataaa agaaagagat
     7261 cttttcctgt tatgtgtgtc gatggccgat cgagatattt ttcaggcaat gtaaaaaccg
     7321 tctggcactg gatacatacc agatccgttt ctcaaaggaa atacagagat actggctgct
     7381 gatgtcactg gcacattgta tttgtgtcac aggaactggc aaatatcgat cttttcaaga
     7441 tggatatcat cgaatctgta gtgccgttca tcaggaaaag tatc
//
