LOCUS       c00223_gnlPro..        20545 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NEMGPHMC_293.
ACCESSION   c00223_gnlPro..
VERSION     c00223_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 05:47:54
            Original ID  :: gnl|Prokka|NEMGPHMC_293
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 20545
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..105
                     /locus_tag="ctg223_1"
                     /transl_table=11
                     /translation="YPARCFGMNMPKSRDIQAKIPLPQAIWNEFWLRY"
     protocluster    1..20545
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6981:20197]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6982..20197
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     protocluster    1..20545
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6981:17968]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      6982..17968
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="2"
     cand_cluster    1..20545
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="chemical_hybrid"
                     /product="Others_HGD_unassigned"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..20545
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             372..1052
                     /locus_tag="ctg223_2"
                     /transl_table=11
                     /translation="MDTLKILVVDDESRMRKLVKDFLTKKNFQVLEAGNGEEAMDIFYE
                     EKDIALIILDVMMPKMDGWEVCREIRKNSKVPIIMLTARSDERDELLGFDLGVDEYISK
                     PFSPKILVARVEAILRRTGQNNPEDVISAGGIVIDKAAHLATVDGKPMELSFKEFELLT
                     YFLENQGIALSREKILNSVWNYDYFGDARTIDTHVKKLRSKMGDKGEYIKTVWGMGYKF
                     EVDE"
     CDS             1049..2593
                     /locus_tag="ctg223_3"
                     /transl_table=11
                     /translation="MTGTGKTDKKFHTLQHQISVVFICLLLLSIFTITLINGLFLEKYY
                     VSKKVEVLEEAKEVLSQMNLDDILQYDTDIEEDKKGATDEISDEIERSSSRNNLTWIIV
                     NEENSGYYYWGENNMAKMLRSKLFGYINDLDQDMQHSRVLKKTDTCTMWQVHDRFAGME
                     YVECWGQFDNGYYFLIRSPLESIEESASISNSFYFIVGLIIIVISGIVILVMTNRITRP
                     ISELTKLSEKMSDLDFDARYQSRAGNEIDVLGDNFNKMSRKLESTISELKSANNKLQKD
                     IEDKIKIDEMRKEFLDNVSHELKTPIALIQGYAEGLNENISDDPESREFYCEVIMDEAS
                     KMNKLVKNLLTLNQLESGKDAPVMERFDIVSLIRGVLGSMHIMIEQKEAAVIFEETEPV
                     YVWADEFKIEEVVTNYTSNALNHLDGERKVEIKVLQEEDCVKVTVFNTGTPIPEEDIPN
                     LWNKFYKVDKARTREYGGSGIGLSIVKAIIESMNQKYGVCNYDNGVEFWFTLDCRQ"
     CDS             2532..2630
                     /locus_tag="ctg223_4"
                     /transl_table=11
                     /translation="MGYVIMIMAWSSGSLWIAGSDKISGYCERSEQ"
     CDS             2813..3451
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg223_5"
                     /sec_met_domain="GATase (E-value: 6.7e-31, bitscore: 97.8,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAIIDYDAGNIKSVEKALHYLGEETTVTRDPQTLLNADKVILPG
                     VGSFGQAMENLHTYGLVPVIHEIVEKKTPFLGICLGLQLLFESSEETPGVEGLGILKGK
                     IVKIPPAPGLKIPHMGWNSLHFQNNGRLFQGIPEQTYVYFVHSYYLQAEEPEIVKATTE
                     YSTCIHASVEKDNVFACQFHPEKSSKWGLKILENFAAVGKDGNTEKEGK"
     CDS             3453..4211
                     /locus_tag="ctg223_6"
                     /transl_table=11
                     /translation="MFTKRIIPCLDVNNGRVVKGVNFVQLRDAGDPVEIAKAYDAAGAD
                     ELVFLDITASCEQRDTVVDMVRRVAANVFIPFTVGGGIRTVDDFKKLLREGADKISVNS
                     AAIDRPELISEAADKFGSQCVVVAIDAKRREDGGWNIYKHGGRLDTGIDAIEWAKKVEA
                     LGAGEILLTSMDCDGTKAGYDLALTRAIADAVSIPVIASGGAGTLEHFYDALTEGGADA
                     ALAASLFHYKELEISQVKDYLSDRGISVRR"
     CDS             4244..4918
                     /locus_tag="ctg223_7"
                     /transl_table=11
                     /translation="MSAISGDWLEALKGEFHQPYYAKLYKTVMTEYQTRKIFPPADDLF
                     NAFHFTPLNEVKVVILGQDPYHNDGQAHGLCFSVKRGVETPPSLVNIYQELHDDCGCYI
                     PNNGYLEKWAKQGVLLLNTVLTVRAHQANSHRGIGWEQFTDAAIQVLNEQDRPIVFLLW
                     GRPAQMKKSMLNNPKHLILEAPHPSPLSAYRGFFGCKHFSKTNEFLVANGLEPIDWQIE
                     NI"
     CDS             5084..6592
                     /locus_tag="ctg223_8"
                     /transl_table=11
                     /translation="MGYTSLAQNAYMILLMIASFSIPQAVSKLISERIALKDYRNAHKF
                     FKGAMIYAMVIGGVVGLFCLFGAGLIIPQNQKDAIPALQILAPTIFLSGILGVFRGYFQ
                     AYRNMMPTSISQIIEQVFNAAVSLLAAWGFINAFSDGTENSIAKWGAAGSTVGTGAGVV
                     TALAFMLLVYGVNRRKILHRVERDHRHQEESYKEIFRVIILVVSPIILSAFVYNVNAYI
                     NGYLFSDILGRRGGDAAQIGILYAEYATYFMTIINIPLTLSSTAPTSMIPEVSALYATG
                     DIEATRECIDQTVQLSMVVSAPCAMGLAVLAQPIVFLLYGNSTGLAANLLILGSFSILL
                     NGMSNISNGVLQAIGQQRIPVITAAIALVVDIVVVVVLLFTTNLGVYALLIAMVIYSVV
                     VCVLNDRAMKKYLQYKNPWKEGYLYPILASVPMGIVAGCICYGLNIFVKSNFICLIVSI
                     PVAAVVYLFAYLIISKPSESQLRRIPGGSYLIRIAEKLPFWQNN"
     CDS             complement(6982..11223)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg223_9"
                     /sec_met_domain="HGD-D (E-value: 1.3e-63, bitscore: 205.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 2.4e-37, bitscore:
                     119.1, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYKTLGIDIGSTTVKIAILDENENLIFADYKRHFANIQETLADL
                     LQEAFDQYGEMTLHPVITGSGGLTLANHLGVPFTQEVIAVSTSLQKLAPKTDVAIELGG
                     EDAKIIYFENGNVEQRMNGICAGGTGSFIDQMASLLQTDATGLNEYAKDYKALYPIAAR
                     CGVFAKTDIQPLINDGATKPDLSASIFQAVVNQTISGLACGKPIRGHVAFLGGPLHFLS
                     ELRESFIRTLKLDEEHTIIPENSHLFAAIGSALNAKEDNSISLTEMKDRLRNSIKLDFE
                     VERMEPLFASQEEYDAFAKRQSSYKVKTGDLATYKGNCYLGIDAGSTTTKTALVGEDGT
                     LLYSFYSSNNGNPLKTTIRSIKEIYELLPKDAKIAYSCSTGYGEALIKAALLLDEGEVE
                     TVSHYYAAAFFDPEVDCILDIGGQDMKCIKIRNKTVDSVQLNEACSSGCGSFIETFAKS
                     LNYTVQDFAKAAVFAQHPIDLGTRCTVFMNSKVKQAQKEGAEVSDISAGLAYSVIKNAL
                     YKVIKVSDASELGRHIVVQGGTFYNDAVLRSFEKIAGCEAIRPDIAGIMGAFGAALIAR
                     ERHQEGAETTMLSIDKINELKYTTSMANCRGCTNNCRLTINKFSGGRQYVSGNRCERGI
                     GKEKNKDHIPNLYEYKYKRIFSYTPLTADKATRGKVGIPRVLNMFENYPFWYTFFTELK
                     YEVVLSPTSTRKIYELGIESIPSESECYPAKLAHGHVTWLIRNGVKFIFYPCIPYERNE
                     FPDAVNHYNCPIVTSYAENIKNNVDELNDPSITFRNPFLAFTSEEILANRLVEEFKDIP
                     AEEVKAAVHKGWEEMAAARRDVQKKGEETLKYLEDTGRHGIVLAGRPYHIDPEIHHGIP
                     DLINSYGIAVLTEDSISHLAPVERPIRVNDQWMYHSRLYAAANYVKTRDDLDLIQLNSF
                     GCGLDAVTTDEVYEILDGSDKIYTCLKIDEVNNLGAARIRIRSLIAAIRAKKAQGQKRT
                     VKPASIDKVSFTKEMRKDYTILCPQMSPFHFSLLQAAFNSCGYNLEVLPNDNKHAVDVG
                     LKYVNNDACYPSLIVVGQIMDALLSGKYDLNKTAVVMSQTGGGCRASNYIAFIRRALKK
                     AGMEQIPVISVNLSGLESNPGFKLTLPLVKKVAYGAVFGDILMKCVYRMRPYELEEGIV
                     NRKHKIWEQRVISFLSGSSISHSQFKKMCREMVHEFDTIPISDVKKPRVGIVGEILVKF
                     LPAANNHLAELLESEGAEAVVPDLIDFMCYCFYNQNFKVENLGFKKSKATMANWGIKAI
                     EWVRKPASEALAQSRHFAPPADIRNLAKMASPIVSTGNQTGEGWFLTGEMMELIHGDVP
                     NIVCIQPFGCLPNHIVGKGVIKEIRREYPTANIVAIDYDPGASEVNQLNRIKLMLSTAQ
                     KNLKKAEEKNA"
     CDS             11422..12600
                     /locus_tag="ctg223_10"
                     /transl_table=11
                     /translation="VIFIKRREKMAEYKLLKTEGRAKRAEFHTVHGTIQTPVFMNVGTI
                     GAIKGAVSTMDLQQIGTQVELSNTYHLHVRPGDKIVKQLGGLHKFMVWDKPILTDSGGF
                     QVFSLAKLRKIKEEGVYFNSHIDGHKIFMGPEESMQIQSNLASTIAMAFDECPSSVADR
                     DYVQKSVDRTTRWLARCKAEMARLNSLPDTINKEQLLFGINQGAVYEDIRIEHAKAISE
                     MDLDGYAVGGLAVGETHEEMYRILDAVVPYLPQNKPTYLMGVGTPANILEGVERGIDFF
                     DCVYPSRNGRHGHVYTNHGKMNLFNAKYELDTRPIEEGCQCPACQHYSRAYIRHLLKAK
                     EMLGMRLCVLHNLYFYNHMMEEIRDALDAGNFAEYKKMRLEGFEEGKINSKR"
     CDS             12849..13148
                     /locus_tag="ctg223_11"
                     /transl_table=11
                     /translation="MNASSGMGMVGAIVWMVVLFGIMYFLMLRPQKKEQKRLQAMLNDM
                     EVGDSIVTTGGFYGVVIDMTEEDVIVEFGNNKNCRIPMRKQAIAEVEKAGSAAE"
     CDS             13338..14420
                     /locus_tag="ctg223_12"
                     /transl_table=11
                     /translation="MDYKIALIPGDGIGPEIVREAKKVLDKVCEKYGHSFSYSEVLLGG
                     ASIDVHGVPLTDEAIATAKSSDAVLMGSIGGDAKTSPWYKLEPSKRPEAGLLAIRKALN
                     LFANLRPAYLYNELRKACPLRDEIIGDGFDMIIVRELTGGLYFGERQTIEENGVKKAID
                     TLSYNENEIRRIAIKAFEIARKRRNKVTSVDKANVLDSSRLWRKVVEEVAKDYPDVTLE
                     HMLVDNCAMQLVRDPKQFDVILTENMFGDILSDEASMVTGSIGMLSSASLNETKFGLYE
                     PSHGSAPDIAGQDKANPIATILSAAMMLRFSLDMDKEADAVEAAVQKVLTEGYRTGDIM
                     SEGCKLVGTKEMGDLIAAAL"
     CDS             14528..16201
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg223_13"
                     /sec_met_domain="ILVD_EDD (E-value: 4.3e-230, bitscore:
                     754.8, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDAVKTGTQQAPHRSLFNALGMTKEEMDRPLVGIVSSYNEIVP
                     GHMNLDKITQAVKLGVAMAGGTPVMFPAIAVCDGIAMGHVGMKYSLVTRDLIADSTEAM
                     AMAHQFDALVMIPNCDKNVPGLLMAAARLNVPTVFVSGGPMLAGHLNGHKTSLSSMFEA
                     VGAYAAGKLDEDGLTECEMKTCPTCGSCSGMYTANSMNCLTEVLGMGLKGNGTIPAVYS
                     ERIRLAKHAGMQVMEMYRKNIRPRDIMTKEAILNALTVDMALGCSTNSMLHLPAIAHEI
                     GMDFDISFANEISAKTPNLCHLAPAGPTYMEDLNEAGGVYAVMNELNKKGLLHTECMTV
                     TGKTVGENIKDCVNLNPEVIRPIDNPYSQTGGLAVLKGNLAPDGGVVKRSAVVEEMMVH
                     EGPARVFDCEEDAIAAIKGGKIVEGDVVVIRYEGPKGGPGMREMLNPTSAIAGMGLGSS
                     VALITDGRFSGASRGASIGHVSPEAAVGGPIALVEEGDIISINIPELKLEIKVSDEEMQ
                     ARKAKWQPREPKVTTGYLARYAAMVTSGNRGAILEVPKAK"
     CDS             16277..17968
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg223_14"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.4e-55, bitscore:
                     176.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLTGAEIIVECLKEQGVDTVFGYPGGAILNVYDALYEYKDQITH
                     VLTSHEQGASHAADGYARATGKVGVCLATSGPGATNLVTGIATAYMDSVPMVAITCNVG
                     TPLLGKDSFQEVDITGIVMPITKHSFIVKDITTLADTVRRAFYIAKSGRPGPVLVDVTK
                     DVTGAKYEYTACAPAEITPKTDTIKDEDIATAVQMIKEAKRPFIFTGGGTIISEASREV
                     TELAHRIDAPVCDSLMGKGGFSGEDPLYTGMLGMHGTKTSNLGVSGCDLLIVLGARFSD
                     RVTGNTKTFAKNAKILQIDVDAAEINKNIVVDASVVGDEKEVLKRILAEVPEMRHSEWT
                     AHISELKEKYPLRYDHSQLTGPYIIEKLYELTKGDAIITTEVGQNQMWAAQYFKYKEPR
                     TFLSSGGLGTMGYGLGAAIGAKMGRPDKTVVNIAGDGCFRMNMNEIATAVRCGRPLIEI
                     VLNNHVLGMVRQWQTLFYDHRYSHTILNDAVDFVKLAEAMGAKAIRITKMEEVEPALKE
                     ALACPGPIVLDCMIDQDLSVFPMVPAGASIDDIFDEEDMKNNEQSV"
     CDS             17952..19034
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg223_15"
                     /sec_met_domain="Aminotran_5 (E-value: 2.8e-53, bitscore:
                     171.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRVYNFSAGPAVLPEEVLKEVAEEMMDYQGTGMSVMEMSHRSAD
                     FQKIIDEAEQDLRDLMKIPDNYKVLFLQGGASQQFAAIPMNLMKNKVADYIVTGQWAKK
                     AYQEAQKYGKANKIASSEDKTFSYIPDCSDLPISPDADYVYICENNTIYGTKFKKLPNT
                     KGKTLVADVSSCFLSEPVDVSKYGIIYGGVQKNIGPAGMVISIIREDLITDDVLEGTPT
                     MLKFKTQADAGSLYNTPNCYCIYVCGKVFKWLKKMGGLEEMQRRNIEKAKILYDFLDQS
                     KLFKGTVVPEDRSLMNVPFVTGDKDMDAKFVKEAKEAGLVNLKGHRTVGGMRASIYNAM
                     PKEGVEALIAFMKKFEEENA"
     CDS             19034..20197
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: Hacid_dh_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg223_16"
                     /sec_met_domain="Hacid_dh_C (E-value: 4.1e-45, bitscore:
                     143.6, seeds: 144, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQYHCLNPIAEKGLGLFDEEYKKSEDLQECDAVLVRSAKMHDME
                     LPESVKVIARAGAGVNNIPVKDCAEKGVVVFNTPGANANGVKELVLAGMLLASRDIVGG
                     IEWVAKEKDQEDIDKLAEKQKKQFAGCEIMGKKLGIIGLGAIGAMVANAASALGMEVYG
                     YDPYISIDAAWNLSRTIKHIKSLDEIYSQCDYITIHVPLLDSTKEMINKEALDKMKDGV
                     VLLNFARDLLVDEDALIEALDSGKVKKYVTDFANHTVAGHKGILVTPHLGASTEESEEN
                     CAVMAVKEVRDFLENGNIKNSVNFPNCDMGTCVAVGRIAICHKNIPNMISQFTKILGAE
                     GLNIADMTNKSKGEYAYTLIDLESAASREALNELKAIEGVSRVRVVK"
     CDS             complement(20339..20428)
                     /locus_tag="ctg223_17"
                     /transl_table=11
                     /translation="MMKYVALFFAILAGDIVAHYICRWIGSKR"
     CDS             complement(20425..20544)
                     /locus_tag="ctg223_18"
                     /transl_table=11
                     /translation="DIQAKIPLPQAIWNEFWLSYCERSETVTICNLNQKEVNP"
ORIGIN
        1 tatcccgcga ggtgttttgg catgaatatg ccaaaatccc gagacataca agccaaaatt
       61 ccattgccgc aggcaatttg gaatgaattt tggctacgtt actgagaacg gagtgaacag
      121 taacggctat ttggtgttgt gaacagcaat acttataatt tttctgtcat atgttcacaa
      181 atcttacata aatctctgct atagtaacca tatgaaagat aaaatctgtt gctgagggcg
      241 attttcccgg attttgcgct gtggctgtaa aggcgctgaa cagtcgtgga ttttaacaat
      301 actcggaaaa cagtataaat aaaaagtaaa aactgtttcg gaaaataatg aagaaaaacg
      361 gaggggatca aatggataca ttaaaaatcc tggtggtgga tgatgagagc cgcatgagaa
      421 agctggtaaa ggatttcctg acaaagaaga atttccaggt actggaagcc ggtaatggtg
      481 aagaagccat ggatatcttt tatgaggaga aggacatcgc actgatcatt ctggatgtca
      541 tgatgccgaa gatggatgga tgggaagttt gccgtgagat tcgcaagaac tcaaaagttc
      601 cgattattat gctgactgca agaagtgatg agagagatga gcttcttgga tttgatctgg
      661 gggtagatga atacatctcc aaaccattca gtccgaaaat ccttgttgca agagtggagg
      721 caattctgag acgtacaggt cagaataatc cggaagatgt gatttcagca ggcggcattg
      781 ttatagataa agcagcacat ctggctactg tggatggtaa gcctatggaa ctgagcttta
      841 aggaatttga acttctgaca tattttctgg agaatcaggg aatcgcactt tccagagaaa
      901 agatcctgaa ttctgtatgg aattatgact actttggaga tgcccgtacg attgataccc
      961 atgttaagaa gctcagaagt aaaatgggag ataaaggtga atatataaag actgtatggg
     1021 gtatgggata caagtttgag gtagacgaat gacaggaacc ggaaaaacag ataaaaaatt
     1081 tcatactctg caacatcaga tttcagtagt gtttatatgt ctgttactgc tttcgatctt
     1141 taccattact ctgattaatg gtctttttct tgaaaaatat tatgtatcca aaaaagtaga
     1201 agtgctggag gaggcaaaag aagtgttgtc tcagatgaat ctggatgaca tcctgcagta
     1261 tgatacagat atagaagagg acaaaaaagg ggcaacagat gagatttcgg atgagattga
     1321 gaggagcagt tccagaaata accttacctg gatcatagta aatgaggaaa acagcggtta
     1381 ttattactgg ggagagaata atatggcaaa aatgctccgc agtaagctgt ttgggtatat
     1441 taatgatctg gatcaggata tgcagcacag tcgtgtgctt aaaaagacag atacctgtac
     1501 catgtggcag gtgcatgacc gctttgcagg catggagtat gtggaatgct ggggacaatt
     1561 tgataatggt tactatttcc tgatccgttc tcctctggaa agtattgagg aaagtgcatc
     1621 tatttccaac agtttttact tcattgtagg attaatcata attgtgatca gcggtattgt
     1681 gattcttgtg atgacaaatc gtattacccg cccgatcagt gaactgacca aattatcaga
     1741 gaagatgtct gatctggatt ttgatgccag atatcaaagc agggcaggta atgagattga
     1801 tgtacttggc gataacttta acaaaatgtc cagaaaactt gaaagcacga tctcagagtt
     1861 gaaatcggct aataacaagc ttcagaaaga catagaagat aagattaaaa ttgatgagat
     1921 gcgtaaggaa tttcttgata atgtttctca tgagctgaaa actcctattg cattgatcca
     1981 gggatatgca gaggggctga atgaaaatat ttccgatgat ccggaaagca gggaatttta
     2041 ctgtgaagtt attatggatg aggcttcaaa gatgaacaag ctggtcaaaa acctgctgac
     2101 gctgaatcag ctggaatccg gtaaagatgc cccggtgatg gaaagatttg acattgtatc
     2161 tctgatcagg ggtgtacttg gttctatgca tattatgatc gaacagaaag aagcagctgt
     2221 gatttttgaa gaaacagaac ctgtatatgt atgggcggat gagtttaaga ttgaagaggt
     2281 tgtgaccaat tatacaagca atgcactgaa ccatctggac ggagaacgaa aagtagaaat
     2341 taaggttctt caggaagagg actgtgtgaa agtaaccgta tttaatacag gtactccgat
     2401 tccggaagag gatatcccaa atctctggaa taaattctac aaagtagata aggcccggac
     2461 aagagaatat ggcggaagtg gtatcggact ttcaattgtt aaggcaatca ttgagagtat
     2521 gaaccagaaa tatggggtat gtaattatga taatggcgtg gagttctggt tcactctgga
     2581 ttgcaggcag tgataagata tccgggtatt gtgaacggag tgaacagtaa ccggtagtat
     2641 gaccggaata aaaacagaca gaagcaaaga aagcactttg caactgtctg tttttgggtt
     2701 atactgtatt ggagcgtttt gatcggatat tttattccgg tctgacatgt gatccggaaa
     2761 acctttggat taccataatg aggaaaacag ataatgacat caggaggata acatgattgc
     2821 aataattgac tatgatgccg gaaatattaa aagtgtagaa aaagcacttc attatcttgg
     2881 ggaagaaaca acagtaaccc gcgatccgca gactttgtta aatgcggata aagtaatcct
     2941 gccgggcgtg ggaagctttg gacaggcgat ggagaatctt catacatacg gacttgtacc
     3001 tgtgatccac gagattgtag agaagaagac accatttctt ggaatctgcc tgggacttca
     3061 gctccttttt gaaagcagcg aggagacacc gggggtggaa ggccttggaa tcctgaaagg
     3121 gaaaattgtt aagattccgc ctgcgccggg acttaagatt ccacatatgg gatggaattc
     3181 cctgcatttt cagaataatg gcagactgtt tcagggaatc ccggaacaga cctatgtata
     3241 ttttgtgcat tcttattatc tgcaggcaga ggagcctgag attgtaaagg ctactacaga
     3301 atacagcacc tgtattcatg cttccgtaga aaaggacaat gtatttgcct gccagttcca
     3361 tccggaaaag agcagcaaat ggggactgaa gatacttgaa aattttgctg ctgtgggaaa
     3421 agacggcaat actgagaagg agggaaaata aaatgtttac aaagagaatt attccctgcc
     3481 tggatgtaaa taacggacgt gtggtaaagg gcgtaaattt tgtgcagctt cgcgatgcgg
     3541 gtgatccggt ggagattgcc aaagcctatg atgcagcagg agcagatgaa ctggtgtttc
     3601 tcgatattac agcatcctgc gaacagagag atacggtagt tgacatggta agacgggttg
     3661 ctgccaatgt atttatcccg tttacagtag gcggcggtat ccgtactgta gatgatttca
     3721 agaaactgct gagagaagga gcagataaga tttccgtaaa ttctgcagca attgacagac
     3781 cggaactgat cagtgaggcg gctgacaagt ttggaagcca gtgcgtagtt gtggctattg
     3841 atgccaagcg cagagaagac ggcggatgga atatttacaa acatggcgga agactggata
     3901 caggaattga tgccatagag tgggcaaaga aagtggaagc tttgggtgca ggggaaattc
     3961 ttctcaccag tatggactgt gacggaacaa aagcaggata tgacctggct cttaccagag
     4021 caatcgctga tgctgtctcc attcctgtga tcgcatcagg gggtgctggg acactggagc
     4081 atttttatga tgcactgacc gaagggggag cagatgctgc actggctgcg tctttgttcc
     4141 attataaaga actggagatt tctcaggtga aggattatct gtctgacagg ggaatttctg
     4201 tcagacgatg accacgaaaa atataagagg tgaaggataa ggtatgtcag caatttcagg
     4261 tgactggctg gaagccctga agggggagtt tcaccagccg tattatgcaa aattatataa
     4321 aacggtgatg acagaatatc agaccaggaa gatttttcct cctgcggatg atctgtttaa
     4381 tgcatttcat tttacaccgt taaacgaagt gaaggtagtg attctgggcc aggatcccta
     4441 tcataatgac gggcaggctc atgggctttg tttttccgta aagagaggag tggagacgcc
     4501 gccgtccctg gtgaatattt atcaggaact tcatgatgac tgtggatgct atatccccaa
     4561 taacggctat ctggagaagt gggcgaagca gggagtgctt cttctgaaca cagttctgac
     4621 tgtacgcgcc catcaggcaa attcacacag gggaatcggc tgggagcagt ttacggatgc
     4681 tgcgatccag gttctgaatg agcaggaccg tcctattgta tttctgctct ggggacgtcc
     4741 ggcgcagatg aaaaaatcca tgttgaataa tccgaagcat ctgattctgg aggcacctca
     4801 tccaagtcct ctgtctgctt acaggggatt tttcggatgt aaacatttca gtaaaacaaa
     4861 cgaatttctt gttgccaatg gtctggaacc aatcgactgg cagatagaaa atatataaga
     4921 aaagaggtaa tgtgtagtca ggtaaaagac acacagtgat aacatgaatc agaaaaacaa
     4981 tttagtaaaa aatgcatcct ttctgatgat tgcagctatg atctccaagg tgatcggtct
     5041 tctgtacaag agtccccttt ccaatattat aggaagcctt ggaatgggct atacaagcct
     5101 tgcgcagaat gcctatatga tccttctgat gatcgcatcc tttagtattc cacaggcggt
     5161 atccaagctg atctccgagc gtattgctct gaaggattac agaaatgcac ataagttctt
     5221 taagggtgcc atgatctatg ccatggtgat tggcggagtg gtcggtttgt tctgtctctt
     5281 tggagcaggg ctgatcatcc ctcagaatca gaaggatgca attccggcac ttcagatcct
     5341 ggctccgacg atttttttgt ccggtattct tggggtattc agaggatatt ttcaggcata
     5401 cagaaatatg atgccaacat ctatctccca gatcattgag caggtattta atgcggcagt
     5461 cagtcttctg gctgcatggg gattcatcaa tgcattttca gatggaacag agaacagcat
     5521 tgcaaaatgg ggggcagcag gttccacagt aggaaccgga gccggagtgg tgactgcatt
     5581 ggcattcatg cttctggtat atggtgtaaa ccgcagaaaa atcctgcacc gggtagagag
     5641 agatcacaga catcaggaag agtcctacaa agagattttt cgtgtgatca tcctggttgt
     5701 ttcgccgatt attctcagcg cctttgttta taatgtaaat gcttatatca atgggtatct
     5761 tttctcggat attctgggaa gaagaggtgg agatgcggca cagattggta ttttatatgc
     5821 agagtatgct acttacttta tgacaattat taatattcct ctgacgctgt ccagtacggc
     5881 acctacttcc atgattccgg aagtttccgc cctgtatgcc accggagaca ttgaagcgac
     5941 cagagagtgc attgaccaga ccgtacagct ttctatggta gtttccgccc catgtgccat
     6001 gggactggca gtgcttgcac agccgattgt atttttgctt tacggaaatt ccacaggact
     6061 ggcagccaac ctgctgatcc ttggttcttt ttcgatcctg ctcaatggaa tgtcaaatat
     6121 ttccaatgga gttctgcagg caatcggaca gcagaggatt ccggtgatta cggctgcaat
     6181 cgcactggtt gtggacattg tggtagtggt agtgctgctg tttactacaa accttggagt
     6241 ttatgcactg ctgatcgcaa tggtgatcta ttctgtggtt gtatgtgtgt taaatgacag
     6301 agccatgaag aaatatctgc agtataagaa tccatggaaa gaaggatatc tgtatcctat
     6361 tcttgcatct gttcccatgg gaattgttgc aggctgtatc tgctatggac tgaacatttt
     6421 tgtaaaatcc aatttcattt gtctgatcgt ttccattcct gttgctgcgg ttgtttatct
     6481 gtttgcttac ctgatcatca gcaagccgtc agaatcacag cttagaagaa ttccgggtgg
     6541 aagctatctg ataaggattg cagagaaact tccgttctgg cagaataatt aaaaacagaa
     6601 gttataaaaa ataaaagagt tatatttcat ggtttaaatg tatttctgaa atagaaacac
     6661 atttaaaatt tctgaaatat aactcttttt ttgagcgcgt ttgaaaaatg cttttcgcaa
     6721 agcaggatat gtagattgcg ggaatgattt ttcaaatatg ctctagagcg tgtctgaaaa
     6781 atcattcccg caatctgcac gtcccacttt gcggtatatt ttgtccgaat tcggttgtcg
     6841 tagcccgcta cgacgccctc atccgaacaa aatctcccac aaattgtgac gcacatcttg
     6901 cgtaaagcat ttttcagaca cgctctaagg cggatatatt gcaaggtaaa atacattgca
     6961 atatatccat tacggtatta tttatgcatt tttttcttct gcttttttca ggtttttctg
     7021 ggctgtggag agcatcagtt tgattcggtt gagctgattg acttcacttg cacccgggtc
     7081 atagtcgatg gctacaatat tggctgtcgg atattctctg cggatctctt tgataacacc
     7141 cttacctaca atgtggttcg gcagacatcc gaaaggctgg atacaaacaa tattcggaac
     7201 atctccatgg atcagttcca tcatctcacc tgtcaggaac catccctcac ctgtctggtt
     7261 tccggtggaa acgatcggag atgccatttt tgccagattt ctgatatcag caggcggtgc
     7321 aaaatggcgg ctctgtgcaa gagcttcgct tgcaggcttt ctcacccatt cgattgcttt
     7381 gattccccag tttgccatgg ttgccttgga cttcttgaat ccaagatttt ctaccttaaa
     7441 gttctgatta tagaagcagt agcacatgaa atcgatcaga tccggtacaa ctgcctcagc
     7501 gccttcagat tccagaagct ctgccagatg attatttgca gcaggcagga acttgacaag
     7561 gatctcacct acgatgccga cacgaggctt tttcacatca ctgatcggaa tggtatcaaa
     7621 ttcatgaacc atttcgcgac acattttttt aaactggctg tggctgatac tgcttccgct
     7681 taagaaagag atcacacgct gttcccagat tttatgtttc ctgtttacga ttccctcttc
     7741 cagttcataa ggacgcatac gatatacgca tttcatcagg atatctccga atacggcacc
     7801 gtaagcaact ttcttcacta atggaagcgt aagtttgaat ccgggattgc tttccagacc
     7861 gcttaagtta acagagataa ccggaatctg ttccataccg gctttcttta atgcgcgtcg
     7921 tataaatgcg atatagttgg aagcacgaca tccgccacct gtctgtgaca tgacaacggc
     7981 cgttttgttc aggtcatatt taccggaaag cagagcatcc atgatctgtc ccacaacgat
     8041 cagagacgga tagcaggcgt cattgtttac atacttcaga ccaacatcca ctgcatgctt
     8101 attgtcattc ggaagcacct ccaggttgta tccgcaggaa ttgaatgctg cctgcaggag
     8161 gctgaaatgg aacggtgaca tctgcgggca gaggatggta tagtcctttc tcatttcctt
     8221 tgtaaaggat actttatcaa tggaagcagg tttgacagta cgtttctgtc cctgtgcttt
     8281 cttcgcgcgg atcgctgcga tcagggaacg gatacggatt cttgcagcac caaggttatt
     8341 tacctcgtca atctttaagc aggtatagat tttgtcactt ccgtcaagga tttcataaac
     8401 ctcgtctgta gtaactgcat ccagaccaca tccgaaagag ttcagctgga tcagatccag
     8461 atcatcgcgt gtctttacat agtttgcggc agcatacagt ctggagtggt acatccactg
     8521 gtcgttgacg cggatcgggc gttccacagg tgccagatga gagatggaat cctcggtaag
     8581 tacggcaata ccatagctgt tgatcagatc cgggatacca tgatggattt ccgggtcaat
     8641 atggtatggg cgtcctgcaa ggacaatacc atggcgtcct gtatcttcca gatatttcag
     8701 ggtttcttcc ccttttttct gtacatcgcg gcgtgcagca gccatttcct cccagccctt
     8761 atgcacagca gctttgactt cttctgccgg gatatcctta aattcctcta ccagacgatt
     8821 tgccagaatt tcctcagaag taaatgcaag gaacggattg cggaaggtaa tggacggatc
     8881 atttaattcg tctacgttat tcttgatatt ttcggcatat gaggtaacga tcgggcagtt
     8941 atagtgattg actgcatccg ggaactcgtt acgttcatat gggatacatg ggtagaaaat
     9001 aaatttcacg ccattgcgga tcagccaggt tacatggcca tgggcaagtt tggcaggata
     9061 gcattcagat tcacttggaa tggactcaat acccagctca taaatctttc tggtggaagt
     9121 aggagagagc acaacctcat acttcagttc tgtaaagaaa gtataccaga aaggataatt
     9181 ctcaaacatg ttcagaacac gggggatacc tactttacct cgcgttgcct tatcagcagt
     9241 aagcggtgtg taggagaaaa tacgcttata tttatattca taaagattcg gaatatgatc
     9301 tttgttcttt tccttaccga taccgcgttc acagcggtta ccgcttacat actggcggcc
     9361 gccggagaat ttgttgatag tcagacggca gttattggta catccacgac agtttgccat
     9421 agaagttgta tatttcagct cgttaatctt atcaatggag agcatagtcg tttctgcgcc
     9481 ttcctgatgg cgttcacggg caatcagtgc ggcaccgaag gcacccatga ttccggcgat
     9541 atccggacgg atggcttcgc agcctgcaat cttttcgaag cttcgaagaa ccgcatcatt
     9601 gtagaaggta ccaccctgta caacgatgtg tctgccaagt tcggaagcgt cagaaacctt
     9661 aataacctta tagagtgcat ttttgataac agagtaagca agacctgcgg aaatatcgga
     9721 aacctcagct ccctctttct gtgcctgctt taccttggaa ttcatgaaaa cagtacatct
     9781 ggtaccaaga tcaataggat gttgtgcgaa aacagcagct tttgcgaaat cctgtactgt
     9841 ataattcagg gatttggcaa aggtttcaat aaaggaaccg catccggagg agcatgcttc
     9901 atttaactgt acgctgtcaa cggtcttgtt gcggatcttg atacatttca tatcctgtcc
     9961 gccgatatcc aggatacagt ctacctctgg gtcaaagaat gcagctgcat agtaatggga
    10021 tacggtctca acctcgccct catccaggag cagggccgct ttgatcagag cctcgccgta
    10081 acctgtagaa caggaataag cgatctttgc gtctttggga agcagttcat agatttcttt
    10141 aatagaacgg atggtagttt ttaacgggtt tccgttgtta ctgctgtaaa aggaatagag
    10201 aagtgttcca tcttcgccta ccagtgcagt tttggttgtg gtggaacctg catcaatacc
    10261 cagatagcag tttcctttat atgtagccag atctcctgtt tttactttgt aggaactctg
    10321 acgttttgca aatgcatcgt attcttcctg agaagcgaaa agtggttcca tacgttctac
    10381 ttcaaaatcc agcttaatgg aattgcggag tctgtctttc atttctgtca gggaaatgga
    10441 gttgtcttct tttgcattta atgcagaacc gatggctgca aaaagatggg agttctccgg
    10501 aatgatggtg tgttcctcat ccagcttcaa agtacggata aaggattctc tcagctcgga
    10561 caggaagtga agcggaccac ccaggaatgc aacatgtcca cggatgggtt ttccgcaggc
    10621 aagaccggag atggtctggt ttacaactgc ctggaaaata gaagctgaca gatccggttt
    10681 ggttgcaccg tcattgatca gtggctggat atccgttttg gcgaaaacac cgcagcgtgc
    10741 agcaatcggg tagagcgctt tgtaatcttt ggcatattca ttcagacctg tggcatctgt
    10801 ctggagaaga gaagccatct ggtcgatgaa agaaccggta ccgcctgcac agataccgtt
    10861 catacgctgt tctacgtttc cgttttcgaa ataaatgatc ttggcatcct caccgccaag
    10921 ctcgatggca acatctgtct ttggtgccag cttctgcaga gaagtagaaa ctgcaataac
    10981 ctcctgggta aaaggaacgc ccagatggtt ggcaagggtc agaccgccgg aacctgtgat
    11041 cacaggatgg agagtcatct cgccatactg gtcaaaggct tcctgaagaa ggtctgcaag
    11101 ggtttcctga atgttggcga aatggcgctt gtaatctgcg aaaataagat tttcattctc
    11161 gtccagaatc gcgattttta cagtagtgga accaatgtca attccaagtg ttttgtaatt
    11221 cataaagtaa attcaagcct cctctttctg tataaaagaa aaaatattga agtaattctt
    11281 tcctattaaa atatctattt ccagatatga atattccgta atattatacg ctaacggtct
    11341 ggaaaagaca atatgaaact ttaccaatga ttaccttatt tgcagttgaa aattcagcta
    11401 tttcgggata taatagaaaa agtgattttt atcaagagga gagaaaaaat ggcagaatat
    11461 aaacttctta aaacagaagg ccgtgccaaa cgtgcagagt ttcatacagt gcatggtacg
    11521 atccagactc ctgtttttat gaatgtggga acgattggtg cgattaaagg cgctgtatcc
    11581 accatggatt tacagcagat cggaacacag gtagaattat caaatactta tcatcttcat
    11641 gtgcgtccgg gtgataaaat agtaaagcag ttaggcggcc ttcataaatt tatggtatgg
    11701 gacaaaccaa tccttacaga ctcaggcgga ttccaggtat tttcccttgc aaagctgaga
    11761 aagatcaaag aagagggggt ttattttaat tcccatattg acgggcataa gatctttatg
    11821 ggaccggaag agagtatgca gatccagtcc aatcttgcct ccaccattgc catggcattt
    11881 gatgaatgtc ccagcagtgt ggctgacagg gattatgtgc agaaatctgt agacaggacc
    11941 acaagatggc tggcccgctg taaagcggaa atggcgagac tgaacagttt gccggatacc
    12001 attaacaaag aacagcttct gtttggaatc aaccagggtg ctgtttatga agatatccgt
    12061 attgagcatg ccaaagcgat ctctgaaatg gatctggatg gctatgctgt cggcggtctg
    12121 gcagttggag aaacccatga agagatgtac aggatcctgg atgcggtagt cccctatctt
    12181 cctcagaata aacctactta cctgatgggt gtgggaacac cggcaaatat cctggaaggt
    12241 gttgaacgtg gaattgattt ctttgactgc gtatatccaa gccgtaacgg ccgccatgga
    12301 catgtatata ccaatcatgg aaagatgaat ctgttcaatg caaaatatga actggacaca
    12361 cgtcctatcg aagaaggctg tcagtgtcct gcatgccagc attacagcag agcctatatc
    12421 cgtcatcttc tgaaagcaaa ggaaatgctg ggaatgcgtc tctgtgtact tcacaatctg
    12481 tatttctata atcatatgat ggaagagata agagatgctc ttgatgcagg aaactttgca
    12541 gaatataaga aaatgcggct ggaaggcttt gaagagggca aaataaactc gaaaagataa
    12601 tctgtatata aaataattat taaatatgcc aaaaactctt gaagtaaaac ggttttttgt
    12661 gtatgatgtg tagtgacgct ttaatcagat tgttatgcat gaaaacaaga tttcatacag
    12721 aaggtaacgg agattataag tggatcgcaa agcagctctt cagtatgagc agccgtcagg
    12781 acggtctgtg aatacatgat ggactgcaaa tatgcagaat aacaggaaaa gttacaggag
    12841 gaatcaaaat gaacgcatca agcggaatgg gtatggttgg cgctattgtc tggatggtag
    12901 tactgttcgg aattatgtac ttcttaatgc ttcgccctca gaaaaaagag cagaagagac
    12961 ttcaggcaat gttaaatgac atggaggttg gcgacagcat tgttactacc ggcggctttt
    13021 atggagttgt cattgatatg acagaagaag acgtgatcgt agaattcggt aataacaaaa
    13081 actgccgtat tcctatgaga aaacaggcaa tcgctgaagt tgagaaagcc ggaagcgctg
    13141 ccgaataatg aaagagaaat gataaaaagc agaacacata gtcagtgatg actgtggttc
    13201 tgttttttta tttttacagt aaaatctccg gaaaacagca cttttgtatt ttttcacttt
    13261 aataggttga aatctgtcgg aaagtgcgtt attataataa caattacgca attagagtat
    13321 ttttggagga aattattatg gattataaga ttgcattgat ccccggcgac ggaatcggac
    13381 cggaaatcgt aagagaagca aagaaagtac tggacaaggt atgcgagaaa tatggacaca
    13441 gcttttccta ttcagaagtt ctgttaggcg gcgcatccat cgatgtacac ggcgtacccc
    13501 ttactgatga ggcaattgcc actgccaaat catcagacgc cgtactgatg ggctctattg
    13561 gcggagatgc aaaaacttct ccatggtata agcttgagcc gtccaaacgc ccggaagcag
    13621 gacttcttgc aatccgtaag gcattaaatc tttttgcaaa cttaagaccg gcttaccttt
    13681 acaatgagct gagaaaagcg tgccctctcc gcgatgagat catcggagac ggatttgaca
    13741 tgatcattgt acgtgagctt acaggcggcc tgtatttcgg agaacgtcag acaattgaag
    13801 agaatggcgt gaagaaagcg attgatacac tttcctataa cgaaaacgaa atccgccgta
    13861 ttgccatcaa agcatttgag atcgcacgta agagaagaaa taaagtgaca agcgtagata
    13921 aggcaaatgt tctggattct tccagactct ggagaaaagt ggtagaggaa gttgccaaag
    13981 actatccgga tgttacctta gagcatatgc tggttgacaa ctgcgcaatg cagcttgtac
    14041 gtgatccaaa acagttcgat gttatcctga cagagaatat gttcggagat atcctttcag
    14101 acgaggcaag tatggtaaca ggctccatcg gaatgctttc atctgcaagc ttaaatgaga
    14161 caaaattcgg tctctatgag ccaagccatg gttcagcacc tgatattgca ggacaggata
    14221 aggcaaaccc tattgcaacc attctttccg cagcaatgat gcttcgcttc tcccttgata
    14281 tggataaaga agcagatgca gtagaagcag cagtacagaa agtcctgaca gagggatacc
    14341 gcacaggtga tatcatgtca gagggatgca agcttgtagg aacaaaggaa atgggcgatc
    14401 tgatcgcagc agctctgtaa gaattgatat taagaggatt cagccggcgc aggcagatta
    14461 cggagtcagg aatttcggtt gaatcattaa aaataaataa aacagtaaga aaagaggaaa
    14521 taaaacaatg agaagtgatg cagtaaaaac aggcacacag caggcacctc accgttccct
    14581 gtttaatgct cttggaatga caaaagaaga aatggacaga cctctggtag gtatcgtaag
    14641 ttcttacaat gaaatcgtac cgggtcatat gaaccttgac aagatcacac aggcagttaa
    14701 gcttggtgtg gcaatggcag gcggtacacc tgttatgttc ccggcaatcg cagtatgtga
    14761 cggtattgca atgggacacg ttggaatgaa atattctctg gtcaccagag acctgatcgc
    14821 agattccaca gaagccatgg caatggcaca tcagtttgat gcactggtaa tgattcctaa
    14881 ctgtgacaag aatgtacccg gacttctgat ggcagcagcc agactgaatg ttcctactgt
    14941 atttgtaagc ggcggcccaa tgcttgccgg acatctgaac ggacacaaga caagcctttc
    15001 cagtatgttc gaggcagtag gtgcttacgc agcaggcaag cttgatgaag acggactgac
    15061 agaatgcgaa atgaaaacat gccctacatg cggatcctgt tccggtatgt acacagcaaa
    15121 ctccatgaac tgtctgacag aggttcttgg tatgggtctg aaaggaaacg gaaccatccc
    15181 tgctgtatat tccgagcgta tccgtcttgc aaaacatgca ggtatgcagg ttatggaaat
    15241 gtacagaaag aacatccgtc caagagatat catgacaaaa gaagcaatcc tcaatgccct
    15301 gacagtagac atggcactcg gatgctccac aaacagtatg cttcaccttc cggctatcgc
    15361 tcatgagatc ggaatggact ttgatatcag ttttgcaaac gagatcagtg caaagactcc
    15421 aaacctctgc caccttgcac ctgcaggccc tacatacatg gaagacctga acgaagcagg
    15481 cggtgtatac gcagttatga acgaactgaa taagaaggga ctccttcata ctgagtgcat
    15541 gacagtcaca ggcaagacag taggcgagaa catcaaagac tgtgtaaact taaatcctga
    15601 agttatcaga ccgatcgaca atccatacag ccagacaggc ggacttgcag ttcttaaggg
    15661 taaccttgca ccggacggcg gcgttgtaaa acgttctgca gttgtagaag agatgatggt
    15721 ccatgaagga cctgcaagag tctttgactg cgaggaagac gcaatcgcag ctatcaaagg
    15781 cggcaagatc gtagagggtg acgtagtagt tatccgttac gaaggaccga aaggcggccc
    15841 tggtatgaga gaaatgctga accctacatc tgcgatcgca ggtatgggac tgggatcttc
    15901 tgtagcactg atcacagacg gacgtttcag cggtgcatcc agaggagcat ccatcggaca
    15961 cgtatcaccg gaagcagcag tcggcggacc gatcgcactt gttgaagagg gggatatcat
    16021 cagcatcaac attccggaac tgaaactgga gatcaaggtt tctgatgaag aaatgcaggc
    16081 aagaaaagct aaatggcagc ctcgtgagcc aaaggtaaca acaggatatc ttgcaagata
    16141 tgctgctatg gtaacttccg gaaacagagg agcaatcctt gaggtaccaa aagcaaaata
    16201 aagatgaaca agtacccggc gggaattgca gcataacctg tgattcctgc ctgaaaagtt
    16261 aggaggatat gtaaagatgc agcttacagg tgctgaaatc atcgttgaat gtttaaaaga
    16321 acagggcgtt gacactgtat tcggatatcc gggcggtgcc atcctgaatg tatatgacgc
    16381 cctctatgaa tataaagacc agatcacaca tgtactgacc tcccatgagc agggagcatc
    16441 ccatgcagca gacggatacg caagagctac cggtaaagtc ggcgtgtgtc ttgcaacttc
    16501 cggccccgga gctaccaatc tggtaacagg aatcgctacc gcatatatgg attccgtacc
    16561 aatggtggca atcacatgta atgtaggaac accgctgctc ggaaaggatt ctttccagga
    16621 ggttgatatt acaggaattg taatgcctat tacaaagcac agctttatcg taaaagacat
    16681 tactactctg gcagacactg tacgcagagc attctatatt gcaaagagcg gacgtcccgg
    16741 tcctgtgctt gtagatgtga ccaaggatgt gacaggtgcg aaatatgaat atactgcctg
    16801 cgctcctgct gagatcacac cgaaaacaga caccatcaaa gacgaagaca ttgcaactgc
    16861 agtacagatg atcaaagaag cgaagagacc atttattttt acaggcggcg gcacgattat
    16921 ctcagaggca tccagagaag tgacagagct tgctcacaga atcgacgctc ctgtatgtga
    16981 cagtcttatg ggtaaggggg gattttccgg agaagatcct ctgtacacag gaatgcttgg
    17041 aatgcatggg accaaaactt ccaatcttgg tgtctcaggc tgcgatctcc tgatcgtgct
    17101 aggagccaga ttcagtgatc gtgtcacagg aaacacaaag acctttgcaa agaatgcgaa
    17161 gattctccag attgacgtag atgctgcaga gattaacaag aacatcgtag tagatgcaag
    17221 tgtggtagga gatgagaaag aagttctcaa acgtattctg gcagaggttc cagaaatgag
    17281 acattcggaa tggactgcac atatcagtga actgaaggaa aaatatccgt taagatatga
    17341 tcattcccag cttacaggcc catacattat tgaaaagctg tacgaactga caaagggaga
    17401 tgccatcatc acaacagagg ttggacagaa ccagatgtgg gcagctcagt attttaaata
    17461 caaagagcca agaaccttcc tttcttccgg tggcctggga actatgggat atggacttgg
    17521 tgcagccatc ggtgccaaga tgggaagacc ggacaagaca gtggtaaaca ttgcaggtga
    17581 cggctgcttc cgtatgaata tgaatgagat cgcaacagca gtccgctgtg gcagaccttt
    17641 aattgaaatc gtattgaaca atcatgtact gggaatggta cgtcagtggc agaccttgtt
    17701 ctatgaccac agatattccc atacaatttt aaatgatgca gtagattttg tgaaactggc
    17761 agaagccatg ggagcaaaag caatccgtat cacaaagatg gaagaggtag agcctgcatt
    17821 aaaagaggct ctggcatgtc cgggacctat cgtacttgac tgtatgatcg atcaggatct
    17881 cagcgtattc ccgatggtac cggcaggcgc aagcattgat gatatttttg atgaggagga
    17941 tatgaaaaac aatgagcaga gtgtataatt tttccgcagg accggctgta ctgccggaag
    18001 aggtactgaa agaagttgca gaggagatga tggactatca gggaactggt atgtctgtaa
    18061 tggaaatgag ccacagaagt gctgatttcc agaagattat tgacgaagca gaacaggatc
    18121 tccgtgacct gatgaagatt ccggataact ataaggtatt attccttcag ggcggagctt
    18181 cccagcagtt cgcagcaatc cctatgaacc ttatgaagaa caaggtagct gattacattg
    18241 taacaggaca gtgggcaaag aaagcatacc aggaagcaca gaaatatgga aaagcaaaca
    18301 agatcgcttc ttccgaggat aagactttct cctatattcc tgactgcagc gaccttccga
    18361 tcagcccgga tgcagactat gtatacattt gcgaaaacaa cacaatctac ggaacaaaat
    18421 tcaagaagct tcccaacaca aaaggaaaaa ctctggtagc agatgtttcc tcctgcttct
    18481 tatctgagcc tgttgatgta tccaaatatg gcatcatcta tggcggtgta cagaagaata
    18541 tcggacctgc tggtatggta atctccatta tccgcgaaga tctgatcaca gacgatgttc
    18601 tggaaggaac acctactatg ctgaaattca aaacacaggc agacgcaggt tctctttaca
    18661 atactccaaa ctgctactgc atctatgtat gcggtaaggt cttcaaatgg ctgaagaaaa
    18721 tgggcggcct ggaagaaatg cagagacgta acattgagaa agcgaaaatc ctctatgatt
    18781 tccttgatca gagcaagctt ttcaaaggaa ctgttgtacc ggaagaccgt tctctcatga
    18841 atgtaccatt cgtaacaggt gacaaggaca tggatgccaa atttgtaaaa gaagcaaaag
    18901 aggcaggact tgtaaactta aagggacacc gtacagtggg cggtatgcgt gcaagcatct
    18961 acaacgctat gccaaaagaa ggtgtggaag cactgattgc tttcatgaag aagtttgagg
    19021 aggagaatgc ataatgtttc agtatcattg cctgaatccc attgcagaaa aaggtctggg
    19081 attatttgat gaagaatata agaaaagcga agatctgcag gagtgtgatg cagtccttgt
    19141 aagaagtgca aaaatgcatg acatggagct tcctgagagc gtaaaggtaa tcgcacgtgc
    19201 aggtgcaggt gtcaacaata ttcctgtaaa ggactgtgca gaaaaaggtg tggtagtatt
    19261 caatacaccg ggcgccaatg caaacggtgt aaaagagctt gtacttgcag gtatgctcct
    19321 tgcttcccgt gatatcgtag gcggtatcga atgggttgcc aaagagaaag accaggaaga
    19381 catcgataaa cttgctgaga agcagaagaa gcagtttgca ggatgcgaga tcatgggcaa
    19441 gaagctgggt atcatcggtc ttggtgccat cggagcaatg gtggcaaacg ctgcttctgc
    19501 acttggaatg gaagtatacg gatatgaccc atacatttct attgatgctg catggaatct
    19561 ttcccgcacc atcaaacata tcaagagcct ggatgagatt tattcccagt gtgattacat
    19621 caccatccat gtacctcttc ttgacagcac aaaagagatg atcaacaaag aagcattaga
    19681 caagatgaaa gacggcgtag tacttctgaa ctttgcccgt gatcttctgg ttgatgagga
    19741 tgctctgatc gaagcattag acagcggaaa agtaaagaaa tatgtgacag actttgcaaa
    19801 ccatacagta gcaggacata agggaatcct ggtaactcca caccttggag catctacaga
    19861 agaatccgaa gaaaactgtg cggtaatggc tgtaaaagaa gtcagagatt tcctcgagaa
    19921 cggaaatatc aagaactctg taaacttccc gaactgcgac atgggaacct gcgtagcagt
    19981 aggacgtatc gccatctgcc acaaaaatat cccgaacatg atcagccagt tcaccaagat
    20041 ccttggtgca gaaggtctga acattgcaga tatgacaaat aagagcaaag gcgaatacgc
    20101 atatactctc attgatctgg aaagcgcagc atccagagaa gcactgaatg agctgaaagc
    20161 aattgaaggt gtttctaggg tacgtgtggt aaaataatag tcagaccata ttattaacaa
    20221 gataaaaaat ctcctgcttt aatcacatga ttgtaatgag caggagattt tttacattga
    20281 aaccgccgtg tactgaatgg tacgcatggt ggtagtgtgc catgcttgtt tggtttattt
    20341 atcgtttgct gcctatccat cggcagatat aatgtgcaac tatatctccg gcgagaatag
    20401 caaagaagag agcaacatat ttcatcatgg attcacctct ttctgattaa gattacagat
    20461 agttactgtt tcactccgtt cacagtaact tagccaaaat tcattccaga ttgcctgcgg
    20521 caatggaatt ttggcttgta tgtct
//
