LOCUS       c00238_gnlPro..        13199 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NEMGPHMC_308.
ACCESSION   c00238_gnlPro..
VERSION     c00238_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 05:47:54
            Original ID  :: gnl|Prokka|NEMGPHMC_308
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3909
            Orig. end    :: 17108
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13199
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[13909:16853]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12944
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..13199
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13199
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(2209..3372)
                     /locus_tag="ctg238_5"
                     /transl_table=11
                     /translation="MILRLERCGMKFAHIGDLHIGKRVHDFSMLEDQRYILDQMMKIFA
                     EQKVDGVLIAGDVYDKTVPSAEAVQLFDEFITGLAKAEIPVYMISGNHDSAERLSFGAK
                     LFESSDIYISQVYDGEMKRIVLKDQYGSISVYLLPFLKPAAVRHALQRDDINTYEEGVM
                     AALQECEIDTTQRNVLVAHQFVTGADRSDSEETWVGGLDNVSAEVFKDFDYVALGHIHR
                     PQKMGRETLRYSGTPLKYSFSEADHKKSVTIVELLEKGNVRVSTVPLIPRQDMRKLRGT
                     YMDVTAKDHYTAENKMDYLQITLTDEEDVPGALQKLRTVYPNLMRLEYDNKRTRENREV
                     QAVEVQEQKSELELFEEFYELLNNEPMKEEQTEFVEKLIQDLKEVRV"
     CDS             complement(3413..4156)
                     /locus_tag="ctg238_6"
                     /transl_table=11
                     /translation="MLTEQRFDIILKLLEEKKSVTVTELRELLDASESTVRRDITALDK
                     AGKLTKVFGGAVALNHKVTAYEPTVAQKSELNKEEKQKIAKYAASLITPDDFVYLDAGT
                     TTGLMLEYLAGVRAAFVTNAVSHAQTLAKMGIRVYLIGGELKSSTEAVVGSQAMQMIQM
                     YHFTKGFFGTNGITRREGFTTPDTSEAIVKSTAMKQCKDVYILTDKSKFGEVSSVTFGG
                     FTDAKILTEEIPEEYQDSKNILKVK"
     CDS             complement(4451..4708)
                     /locus_tag="ctg238_7"
                     /transl_table=11
                     /translation="MKEFKYVVTDNEGIHARPAGELVKLVKGFESTISIEKEGKKVDCR
                     KLLALMGLGVKKGHEVTFTIEGADEEAAYEAVSKFMQDNL"
     CDS             complement(4768..6681)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg238_8"
                     /sec_met_domain="PTS_EIIC (E-value: 1.2e-20, bitscore:
                     63.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRITDLLDRRSVSLTAAPKTKSETLDMAVDLMVKSEKISNREAYR
                     KQVYLREEESTTGIGEGIAIPHGKCDAVKKPGLAAMVIKNGVEFEALDDEPVTLLFLIA
                     APNTEDNIHLDVLSKLSVMLMDEEFTESLRNASSVDEFMDIIDRADSEKKDIDERLADT
                     GSTEGTQAKILAVTSCPTGIAHTYMAAEGIEKAAKAKNCFIKIETRGSGGAKNVLTDQE
                     IADADCIIVAADAKVPMERFDGKKVIECQVSDGISKADQLIDRAINGDAPVYHAAAGSQ
                     TSSAGNKSGGSVGHKIYMQLMNGVSHMLPLVVGGGILIAIAFLIDGLSVDLSALPADQR
                     ANFGTITPVAALFKGIGGTAFGFMLPILAGFIAMAIGDRPALALGLVGGMMAANGKSGF
                     LGALLAGFAAGYIILGLRKLCDKLPEALEKIAPVLIYPVVGILVMGLLMTFIVEPVMGG
                     INTGLNNALTGMGSSSKVILGIVLGGMMAIDMGGPFNKAAYVFGTAAIAAGNYDIMAAV
                     MIGGMTPPCAIALATLLFKDKFTKEERDAGPTNFIMGLAFITEGAIPFAASDPLRVLPS
                     CIVGSAVAGAISMAFDCTLMAPHGGIFVFPVVGNAVMYLVALVAGTVISAVLLGLLKKK
                     AA"
     CDS             complement(6699..7610)
                     /locus_tag="ctg238_9"
                     /transl_table=11
                     /translation="MIYTVTFNPSLDYIVSVDDFKLGLTNRTSSELMLPGGKGINVSTV
                     LMNLGIENTALGFTAGFVGKEIIRRLHEMGVKSEFIQISEGVSRINLKLKSIDGTEING
                     AGPVISKDKVEELMKKLEELGEGDVLFLAGSIPSSMPDDMYEQIMARLDGKGVMIVVDA
                     TKDLLVNVLKYHPFLVKPNNHELGEIFGIELKTRKDVIPYGKKLQEKGARNVLISMAGE
                     GAVLVAEDGQVFEEPAPKGRLVNGVGAGDSMVAGFVAGWMEKKDYEHAFHMGIAAGSAS
                     AFSENLARKEEIEAVYRQITEK"
     CDS             complement(7922..9337)
                     /locus_tag="ctg238_10"
                     /transl_table=11
                     /translation="MWEAINSFLTTVDNLVWGVPLMVLIMAGGILLTARLGLLQMRRLP
                     LALKWMFKNEEEGDGEISSFAALCTALSATIGTGNIVGVATAVCAGGPGALFWMILAAF
                     FGMATKFSEGLLAVKYRVVAEDGHSLGGPFYYIEKGMGTKWKWLAKIFAFFGVCVGLFG
                     IGTFSQVNGISSAVQNFFDPNKSNCVNIPFLGEYSWAVVISSLILAACVAAILIGGLKR
                     IATVSQIIVPFMAVIYLIFSVALILLNITEIPAAIVTVVKGAFNPSAVTGGVVGTMIVS
                     MQKGVARGIFSNEAGLGSAPIAAAAAQTKEPVRQGLVSMTGTFIDTIVICTMTGLSIVL
                     TGAWQVEGLEGVQVTTYAFQHGLPIPGQISAFVLMICLVFFAFTTILGWDYYSERCLEY
                     LTNGHKKTILTYRWLYILAVFIGPYMTVSAVWTIADIFNGLMAIPNMIALFALSGVIVK
                     ETKAFFAAEKHKM"
     CDS             complement(10001..11680)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg238_11"
                     /sec_met_domain="HGD-D (E-value: 1.6e-17, bitscore: 53.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.1e-65, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPEGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
     CDS             complement(11673..12944)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg238_12"
                     /sec_met_domain="HGD-D (E-value: 2.7e-56, bitscore: 181.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWGAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLWPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERAFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
ORIGIN
        1 cctgtaatac attacaattt tccttttgat tcactgtttc actgctgtga ttctgtgaca
       61 gttccggatc agttttcatt ctctgtctta tatcttcttc atggatccat gtcagtacag
      121 gttcgtccaa ttgattctgc agctgttcct gaatactttc cagctggctc ttcctctttt
      181 caagactgat ctgtaatttc tgaaattctt ttgtatgctg ttctgactgt gtggtgaact
      241 cttccttttt cttcagtaaa tcctgatgag cttttttctg ttttttgagt tcttctaatc
      301 ctgtctgtac gatactttcc tgatttttta caaacaagca taattcatga tcaggaagtt
      361 cctttcgaag tattttttct gcctcctctt gtgacagaaa ctgtgctgca tagtctttaa
      421 ctccttctgt caattcttcc ctgcaacgct tcaccagtcc tgcagtctct cctgcctgca
      481 cgcttgcgtc agatgccgct ttttccgcag cttctgttaa ctttttctgt tttttcagtt
      541 gttcttctgt aggaacttcc ttcggagtct gcgtaagctt tggatgatga acagaaccac
      601 ataccggaca cggcattcca tcctgaagtc ctgctgccaa tatccccgcc tgcccatcca
      661 gataagcctg ttccattttg ttcaggattt cttttatttc tgcccgtttc tgagaagcgg
      721 tcagataagc cttctttttg ctttctgctt tcttttccag atcctgatac cgtttctgct
      781 gatcttctat tttctgtatc tgctgcaaac gtacgaccag gctgttctct ttgatttcca
      841 gattcccacc ggaaacaatt ttctcttcca gatcagttaa atcctttttt atctgtttcg
      901 caaattgttc ttcctgttca gactgtattt tcagttcact gatttttgtc tgaagaaact
      961 caagatttcc gcagttctta taaacccctg cataaagatt atctattttc tctttccgga
     1021 aatctgtttc tgctttttct ttctctgcac tgtctgttgt ctgatattct ttttgttttt
     1081 cttcaagaac aattttcttt tctttctgac gattctgcag tgcaatactg tctgtttcca
     1141 atttttcaat ctgttttgag acattttcta tttctctgag cagattttcc agatttgtat
     1201 aacgcttcag attctctttt tctttctgta tggaaagtat caggcgttgg atctcctctg
     1261 gttcctttgc cccattttct gcatcttttt gtgcctgttc caactgtgga agcaatactt
     1321 ctttctcttg cagaagttgt tccttccttg cctttgcatc tgcttcttta tgagcctttc
     1381 ccaaaagctg atttactttt tcaagttctg tatcattctc tttgatctgc ttatttacag
     1441 ctttcaagtt atccttatct gccttcagaa actgctccag aatttccaga ccttcttcca
     1501 gatttccttc aaagccattc ttctccatca ataaccactg ttgtcccaac tgattttctg
     1561 tagaatatct gacctgttcc gtatactgac ggatacttct cagcagctct ttatacgctt
     1621 tgtccagacc gccggcttcg aattttaatt tttcctgaat taccttataa atatccgtat
     1681 ggaaaagctt tctgaaaata ttgctgcgtt cctctgtatc agccaacagt aattttctga
     1741 aatctccctg tgcaatcatg gcgatctgtg taaactgctt catatccagt ccgatcagct
     1801 cagtaaccgc ctgattcact tcctttagct ttgtcacagg agctcttcca tcagaaaaag
     1861 taagcaacgc ctcccccttc tgggtagtca ttccagtgcc tctggtcttt ggccgctcat
     1921 aatccgggct tcgcttcact gtatacactg catctttata ttcaaaaata tattccgcat
     1981 acgtaggtgt ttccggtttt gcatacttac ttctgagcat ggatgcctcc cggactcctc
     2041 cgcttgtctc cccatacaac gcaaatgtaa tcccatcaaa gatcgtcgtt tttcccgctc
     2101 ccgtatctcc ggtcaccaga aaaaggccct gtcctccaag ctgtgtaaaa tcgatcacag
     2161 tctcatccgc atatggacca aatgcatata atgtcaactt caatggtttc atacgcgcac
     2221 ctccttcaga tcctggatca gtttttccac aaactctgtc tgctcttctt tcataggttc
     2281 attatttaac agctcataaa actcctcaaa cagctccagc tctgactttt gttcctgaac
     2341 ctccactgcc tgaacctccc ggttctcacg tgttcgttta ttgtcatatt ccagacgcat
     2401 cagattggga taaacagtac gcagcttctg gagtgccccc ggcacatctt cctcatctgt
     2461 cagggtaatc tgaagataat ccatcttatt ttcagcagta taatgatcct tcgccgtcac
     2521 atccatatag gttcccctca gcttacgcat atcctgtctg ggaatcaaag gtactgtact
     2581 gaccctcaca tttcccttct ccagaagctc cacaatcgtt accgactttt tatggtctgc
     2641 ttccgaaaaa gaatacttaa gcggcgtccc actgtaacgc aaggtctctc tccccatttt
     2701 ctgaggtctg tggatgtgtc ccagtgccac atagtcaaaa tccttaaata cttccgcact
     2761 gacattgtca agaccgccaa cccatgtttc ttctgagtca cttctgtctg ctccggtcac
     2821 aaactgatgt gccaccagca catttctctg tgtcgtatcg atctcacact cctgcagagc
     2881 agccataaca ccctcttcat aagtattaat gtcatccctc tgcaaagcat ggcgtactgc
     2941 cgcaggtttc aaaaaaggca gaagatatac agatattgat ccatactgat cttttaacac
     3001 aatccttttc atctctccat cataaacctg cgaaatataa atatcactgc tttcaaacag
     3061 ctttgcccca aaggaaagcc tttctgctga atcatgattt ccactgatca tgtacacagg
     3121 aatctcagct ttagccagtc ctgtaataaa ctcatcaaac aactgcactg cctctgccga
     3181 cggcactgtc ttatcataaa catcccctgc gattaaaact ccatccactt tctgttccgc
     3241 aaagattttc atcatctgat ccagaatata cctctgatcc tccagcatgg aaaaatcatg
     3301 cacccttttt ccaatatgca aatccccaat atgcgcaaac ttcatcccac atctctccaa
     3361 tcttaatatc attcctgcct gctctgtctg ccggcggcat actgtcaatt atttatttca
     3421 ccttcagaat atttttgcta tcctgatact cctccggaat ttcttctgta agaattttag
     3481 catctgtaaa cccgccgaat gtcacagaac ttacttcgcc aaactttgac ttatctgtca
     3541 gaatatatac atctttgcac tgcttcattg cagtactctt tacaattgct tcgctggtat
     3601 ccggtgtggt gaagccttct cttctggtga ttccatttgt tccgaaaaat ccctttgtaa
     3661 aatgatacat ctggatcatc tgcattgcct gactgcctac gactgcttct gtggaactct
     3721 tcagttctcc tccgatcaaa taaacccgga ttcccatctt tgccagagtc tgggcgtggg
     3781 atactgcatt ggtgacaaag gcagctctta cacctgccag atattccagc atcaggccag
     3841 tggtggttcc tgcgtccaga taaacaaaat catccggtgt gatcaggctg gctgcatatt
     3901 ttgcgatctt ttgcttttct tctttattta attctgattt ctgcgctact gtcggttcat
     3961 aggcagttac tttatgattt aatgctactg caccgccgaa aaccttggta agttttcctg
     4021 ctttgtccaa tgcagtaatg tctctgcgca ctgtggactc tgatgcatcc agaagttctc
     4081 tcagttctgt tactgtaaca ctcttttttt cttccagaag cttcagaata atatcaaatc
     4141 tctgttctgt aagcatgtac ccctgcctcc attgtatatt tgctttgatt gtttacttct
     4201 gattattttc tccgatatct acgaattgct ccgctgcttc gtagctcccg caattctaca
     4261 aacattcgga atccgcagat ttacttcgta aatcgctact tcctcatgtt tggcgggtcc
     4321 caagttcaaa agtcttatcg tgcaagcacg aacgactttc tgccttttga ccctgatatt
     4381 tcattataac agaaacagga gatgaatgca tcatctcctg tctgtcagtt tcttatttta
     4441 ttccgtaaat ttacaggttg tcctgcatga atttgctcac tgcttcatat gctgcttctt
     4501 catcagcacc ttcgattgtg aatgttactt catgaccttt cttaacgcca agtcccatca
     4561 gtgcaagaag ttttctgcag tctacttttt taccttcttt ttcaatagag attgttgact
     4621 caaatccctt taccagtttt acaagttctc ctgcaggacg tgcgtggatt ccttcgttgt
     4681 ctgtaactac atacttaaat tctttcattt tgatatcctc catgttcttt attttaattt
     4741 tttgttattg cttttttatt tcgctgctta tgctgctttc ttctttaaca gaccaagaag
     4801 aactgcagag attactgttc ccgcaaccag tgcgaccagg tacataactg cgtttccaac
     4861 cacagggaat acgaaaattc caccgtgtgg tgccatcagt gtacagtcga atgccatgga
     4921 aatcgctcct gccaccgcag atcctacgat acaggaagga agtacacgaa gggggtcaga
     4981 tgctgcgaat ggaatcgcac cttctgtgat aaatgcaaga cccatgataa agttggtagg
     5041 acctgcatct ctctcttctt ttgtgaactt atccttaaac agcagtgttg ccagtgcaat
     5101 tgcacaggga ggtgtcatac cgccaatcat aactgctgcc ataatatcat agttacctgc
     5161 tgcaattgca gctgttccga atacatatgc tgctttgttg aacggaccac ccatatcaat
     5221 agccatcatt ccgccaagca caatgccaag tattacttta ctagaacttc ccattcctgt
     5281 caaggcatta ttcagacctg tgttgatacc gcccataacc ggctctacaa taaatgtcat
     5341 caggagtccc ataacaagga ttccaactac aggatagatt aaaacaggag cgatcttttc
     5401 cagggcttcc ggaagtttat cacataattt acgaagtcca agaataatat atccggctgc
     5461 aaagcctgca agcaaagctc caaggaaacc agatttaccg ttggctgcca tcataccgcc
     5521 taccagacca agtgcaagtg ccggtctgtc accgattgcc attgcaataa atccggcaag
     5581 gatcggaagc ataaatccga atgctgtacc accgatgcct ttaaacagag ccgctaccgg
     5641 agtaatggta ccgaagtttg ctctctgatc tgccggaagc gcacttaaat ctacacttaa
     5701 tccatcgatc aggaacgcaa tggcgatcag gataccaccg cctacaacca acggaagcat
     5761 atgagatacg ccattcatca gctgcatata gatcttatgt cctacactgc cgccggattt
     5821 gttaccggca gaagatgtct gggaaccggc tgctgcgtgg tagaccggtg catccccatt
     5881 gattgctctg tcaatgagct gatctgcttt actgattccg tcggatacct gacattcgat
     5941 cactttttta ccatcgaaac gttccatggg aactttggca tctgctgcga caataataca
     6001 gtctgcatca gcaatctcct gatctgtcag cacattcttt gcaccgccgg atccgcgggt
     6061 ttcgatcttt ataaaacagt tctttgcttt tgcagctttt tcaattcctt ctgctgccat
     6121 gtacgtatgt gcgataccgg taggacaaga agtaacagca aggatcttag cctgtgttcc
     6181 ttctgttgat ccggtatctg ccagtctctc atcaatatct ttcttttcac tgtctgccct
     6241 gtcaataata tccataaact catctacaga cgatgcattg cgaagagatt ctgtaaactc
     6301 ctcatccatc agcatcacag agagcttgct gagtacatcc aggtgaatgt tatcctctgt
     6361 attcggcgct gcgatcagga ataataaggt tacaggttca tcatccagtg cctcaaactc
     6421 tacaccattt ttgatgacca ttgccgcaag tcccggcttc ttaactgcat cacatttacc
     6481 atgaggaata gcaattccct cgccaatacc tgttgtgctc tcttcttctc ttaaatatac
     6541 ctgtttacga taagcctcac gattgctgat cttctcactc tttaccatca gatcaactgc
     6601 catatccaga gtttctgact ttgttttcgg agcagctgtt aacgatacgc ttcgtctgtc
     6661 aagcaggtct gttattctca tcttttcttc cccctttatt atttttcggt tatctgacga
     6721 taaaccgctt ctatttcttc ttttcttgca agattttcag aaaatgcact tgcacttcct
     6781 gctgcaattc ccatgtggaa tgcatgttcg taatccttct tctccatcca gcctgcaacg
     6841 aatcctgcta ccatggaatc tcctgcaccc acaccattta ccagcctgcc ttttggtgca
     6901 ggttcttcaa atacctgtcc atcctctgct accagaactg caccttcgcc ggccatggag
     6961 atcagcacat ttcttgcacc tttttcctga agtttctttc cataaggaat tacatctttt
     7021 cttgttttta attctatacc gaagatctcg cccagttcat gattatttgg ttttacaagg
     7081 aacggatgat atttcaggac attgaccaga agatcctttg tggcatcaac tacgatcatc
     7141 acaccttttc catccagcct tgccatgatc tgttcataca tgtcatctgg catagaagat
     7201 ggaatgctgc ctgccaggaa aagtacatcg ccttctccaa gctcttccag tttcttcatc
     7261 agttcctcta ctttatcctt gctgatcacc ggtcctgcac cattgatctc ggttccgtca
     7321 atagatttca gtttcagatt gatccttgaa accccttcac taatctgaat gaactcagat
     7381 ttcactccca tctcatgtaa tctacggata atttctttcc ctacaaaccc tgcagtaaat
     7441 ccaagtgcag tgttctcaat cccaagattc ataaggactg tggaaacatt aattcccttt
     7501 ccccccggaa gcatcagctc tgaacttgtt ctgtttgtca gccccagttt aaaatcatct
     7561 accgaaacga tatagtccag agatggatta aaagtcactg tgtaaatcat ctcttcttgc
     7621 cctcccgttt tatattggta tcctttcgga gtctttattt cactttcacc aaaagattcc
     7681 aaaagtacat attgtcatgt cttttctgca tgttcatgac tgttttttgt ttatgatctt
     7741 agtatactgt catattcatc caaagtcaat caaactaatt cataaaaata atgactgatt
     7801 ttggtttact ttgcacaaaa agtcataatc agtcaaatgc aagcagaaaa aatcctctga
     7861 tcaggattgc tataaattcc ataatcagag gatttactgt tattttatta cttttgattc
     7921 cttacatttt atgcttttct gctgcaaaga acgcttttgt ttcttttacg atcactccac
     7981 ttaatgcgaa caatgcgatc atattcggaa tcgccatcag tccgttgaag atatctgcga
     8041 ttgtccatac agcacttact gtcatgtacg gtccgataaa tactgccaga atgtaaagcc
     8101 agcgatatgt aaggattgtt ttcttatgtc cgtttgtcag atattccaga catctttcac
     8161 tgtaataatc ccatccaaga attgtagtaa atgcaaagaa taccagacag atcattaata
     8221 caaatgcaga aatctgtcca gggatcggaa gtccatgctg gaatgcatag gttgttacct
     8281 gaacaccttc cagaccttct acctgccatg cacctgtcag cacgatggaa aggcctgtca
     8341 ttgtacagat cacgattgta tcaataaatg taccagtcat gcttacaaga ccctgacgta
     8401 caggctcttt tgtctgagct gctgccgctg cgataggtgc gctaccaaga cctgcttcat
     8461 ttgaaaagat accacgagcc acacctttct gcatggatac gatcattgtt cctaccacac
     8521 cgcctgtcac tgctgacgga ttaaaggctc ccttcacaac tgttacgata gctgccggga
     8581 tctctgtaat gtttaaaaga atcagcgcta cactgaagat cagatagatc accgccataa
     8641 acggtacaat aatctggctg actgttgcaa ttcgtttcag accaccgatg aggattgctg
     8701 caacacaggc tgcaagaatc agggaagaaa ttacaactgc ccaggaatac tctccaagga
     8761 acggaatatt tacgcagttt gatttgttcg gatcaaagaa gttctgaact gcactggaaa
     8821 taccatttac ctgactgaat gtaccgattc cgaaaagacc tacacataca ccaaagaatg
     8881 caaagatctt tgcaagccat ttccattttg ttcccatacc tttctcaata taatagaaag
     8941 gaccaccaag gctgtgaccg tcttctgcta ccacacggta tttcactgca agaagacctt
     9001 cggaaaattt tgttgccatt ccgaagaatg ctgccagaat catccagaat aaagctccgg
     9061 gacctccggc acagacagca gttgcaacac cgacgatatt accggttccg attgtggcgc
     9121 tcagtgctgt acataaagct gcaaagctgg aaatctcacc atcgccttct tcttcgttct
     9181 taaacatcca tttcaatgca agagggagtc ttcgcatctg aagaagtcca agtctggcag
     9241 ttaacaggat accacctgcc atgatcagga ccataagggg cacgccccag accagattgt
     9301 ctactgttgt caaaaaagaa ttgatcgctt cccacataat aataaatctc ctttttcttt
     9361 taaaaagtgt aatatattgt acagctggga aacaaagtaa taacagaccg tttcaaaaat
     9421 cagaagttca gaaaatactg ttcatatagt tcatatgaat cagcggggat gataaagcat
     9481 cctctgtcct tttgcctgag agattcaaga cacgaatcag ataaccattt gtgggcagct
     9541 attgataatt cgtgttattt gcaccttcgg cccccgatct aacgggtgtc tccagagaaa
     9601 cgatccattt gcagttcttc cctgcatcca gggaacctga gagttttact ccttcggcgg
     9661 gtatagcctt ttgtgtggct tcctctttcc tgcaaacttc acctcgttaa tttgctgtta
     9721 ctgtgatata ctatagctct taaatttgaa ctcgtcaata gaaaattaaa cttttataaa
     9781 aaaagtataa aaattgttac tgttcactgg taatatccag caaggtattt tttgtgagcg
     9841 aaggtcacag aaaacccgag acatactgcg cgaatttatg cgattagcat aaattaagtt
     9901 tgcgaagcaa tcgatactcc ttgggcattg cacaaggagg ttcatatttc ctgcatcgcg
     9961 aagcgtgttg ctgagaacgg agtgaacagt aactaaaaat ttacacatca gccatatcag
    10021 ccgcaaacag tgctgcgcca agtgcaccgc aaagctgagc cttgtcactg atcaccagct
    10081 ttgttccaag cttctcttcc agtgtcttta ccagaccctt attcttagaa acaccaccgg
    10141 tcatcatata tttctcctca ccgcccacac gtctggtaag ggcggcagtc tttacggcaa
    10201 ccgccttatt caggccatgg acaatatcat ctgttgcctt attctgggcg atcaatgata
    10261 caacttctga ttctgcaaat actgtacaca tactggaaat tgtaatatct tctttgaatt
    10321 ccagcccaca ttcgctcatc tgatccagat tcatttccat ggtacgtgcc atcatttcca
    10381 gaaatcgtcc ggttcctgcc gcacatttgt cattcataac aaagtttgca actgcaccgt
    10441 tctcatccag tcggatcacc ttgctgtcct gtccgccaat atcaataaca gtacggactt
    10501 ccggattcag gaaatgcgca cctcttgcat gacaggtgat ctctgtgata ctcttatcac
    10561 catttttaat agctgtacgt ccgtatccgg tagtaaccag cgcatcaata tcttctctct
    10621 gcaatccggc ctccttcaat gcctctgcaa gggcacggtc tgctccgata gcagctcctg
    10681 ctcctgtagg caggataatg ctggtcacaa tctcatgatc tttatttaaa atcaccacat
    10741 ctgtactggt agaaccactg tcaatccctg cgaaataacc ttttcccatt tttctctctc
    10801 cttttgtgtc tccatctatg gtctgctcca gtgtttcagg ctgaatgctc tctgcaaaag
    10861 cttccagtct ggtaagaagc tgaccgctgc tctgaatagt ataatctgat tcgattttta
    10921 aaagaggtac atctgtatga ttcttgatct cagcatattc gaagctgtaa aaatcacaaa
    10981 acttcactgt atgataaata atccccgcaa cagacggatc attataaagc ttcttacgac
    11041 ctgtcgggtc catcatacgc atacatggaa tctgccccag aatctcacct gcataccagt
    11101 ccatcagctc atcaaaagaa gcaccctccg gtggaagtat atttcccaca gaacggttat
    11161 gcacgcaggt atcattctct acaggaagag gcatagcttt gctggtcatt tcaaataatt
    11221 cctgccccat tctggcgcca agcactgcaa tatgggactt tgtgattttc tcctgtgcat
    11281 ggaaagcagc ccggaatttt ccggcatcaa actctgtgcc tttgtactgt gcataagcct
    11341 tcgccagccc ttttaactgt acagccatac gctctctgct acaggcactg tcacagtgaa
    11401 gcacatccaa aatatagaga aaatccagct tgccgctttc aagcagaatg tcatagacac
    11461 tccggatagt atcacagcag ctcaccagga caagttcctt gattttcccc tccatgactc
    11521 cttccagaag tgtttttcca aaaccgcaga tattgggatg tgaaacctga tcggccaggt
    11581 caaatccctc cggcatatga ttaaagttct cacattcccc gccaagagat tccagaagtt
    11641 caattggggt atatttacag acatagtaag ttttattcat tctcagcacc tcccagcatt
    11701 tccagaaaag ctcccagcct ggtggaagtc tgtccttctc ctccatggct tcgatcacac
    11761 ccgtcaccgt ccaggatcaa aaggggcaga ccggcttcct cgaacttctt ctttgcaagc
    11821 tgtgccgcac caagcgtatg tttacatccc caatgtccaa accacacagc accgtctgct
    11881 cctgcctgtt tcgcatggcg gataccggct tcaatccttc taagggcact tccgttcagt
    11941 gaatgatata ccattctttc tgccattgct tcaaaggggt tctcaggatc aaaatccggc
    12001 tcacaggttt ctgcaagttc acatcctacg atctgggctt tctcactgaa gcaaagctcc
    12061 tggcgcactg catccgacca gaatggaatg gtatgcatcc agtaaatgtg cttccctttc
    12121 gctgccggtg ctttcttaat atcttcaaga agcatctgtg tatacttctc ttcttctgct
    12181 gttcccagaa ggatattgtt tgtcattcct gcatacaagg gtgtgaccag atcagagggc
    12241 acatatctgt ctgcacgcat ctgctgatat tttttgtaat tctccagagt ccgcttactg
    12301 caggcaagac gttcctttaa tctgtcctca gagattgttt ttcctgtatt tttttccaga
    12361 aatattttta aatcctttaa ctgatctgcc acatactgta cattctctgt ggtctgattc
    12421 catggtacat caatggcaaa tacaggtacc tggtaaaaat ctgccagggt acggaaggtg
    12481 agcaggttag catcgcaggt caggttggta taaacaatac atttaggctt tggcagaagt
    12541 cctttctgcg ctgcaccaag aaatgtcttg tgataactgc acagtgtctc tgcaattccc
    12601 tgattctctg cctgctgcaa aaatgccctc tctgctttgc ttgcagaaag atagcaggaa
    12661 aatccttcta cattataggg atgtaatccc acctcctgca tcatttcgca gggtgtaaaa
    12721 atacttacaa taacagaatc ttccggtttc tgaaggggcc acagcatggt atccatcatc
    12781 aggtttgcaa gatgcctgtc tgcaggcatc agtctcttgt cctgcatgta acggaacttc
    12841 agattctgcg ccccccaacc ggtttttaac agccggcggg ctgactgagg ctttttatcc
    12901 gtcagatttt ccacataatg accaaatgtc tcaataatct ccatagtctg tctcttcctc
    12961 attatggtaa taataattta tcaattgtca gtgcacaaat agtgccacgg aatattttaa
    13021 taatatcttt ttgggaagtc aagttgaatt ttcgttactg ttcacacacc actattctgc
    13081 gaggtgtttt ggcatgaata tgccaaaatc ccgagacata caagccaaaa ttccattgcc
    13141 gcaggcaatc tggaatgaat tttggctaag ttactgtgaa cggagtgaac agtaacgaa
//
