Select genomic region:
Overview
14.1
23.1
24.1
28.1
31.1
43.1
47.1
56.1
71.1
89.1
89.2
111.1

### Identified primary metabolite regions

c00014_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_22)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 14.1 | PFOR_II_pathway | SCFA | 19,854 | 43,390 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%

c00023_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_66)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 23.1 | Others_HGD_unassigned | Putative | 86,064 | 108,076 |

c00024_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_67)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 24.1 | Acetyl-CoA_pathway | SCFA | 5,590 | 39,720 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 61%

c00028_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_71)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 28.1 | Rnf_complex | E-MGC | 8,249 | 33,260 | Rnf complex C. sporogenes | RNF | 100%

c00031_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_74)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 31.1 | Fumarate2succinate | SCFA | 32,100 | 55,439 |

c00043_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_86)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 43.1 | Rnf_complex | E-MGC | 12,688 | 36,818 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 14%

c00047_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_90)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 47.1 | GR_eut-pdu-related | Putative | 1 | 24,150 | Trimethylamine synthesis C. sporogenes | TMA | 50%

c00056_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_99)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 56.1 | succinate2propionate | SCFA | 86,235 | 106,231 | Succinate to propionate B. theta | PRO | 33%

c00071_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_114)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 71.1 | Pyruvate2acetate-formate | SCFA | 1 | 12,183 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%

c00089_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_132)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 89.1 | Others_HGD_unassigned,TPP_AA_metabolism | Putative | 1 | 23,738 |
Region 89.2 | Others_HGD_unassigned | Putative | 49,728 | 72,671 |

c00111_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_154)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 111.1 | Putrescine2spermidine | Aliphatic_amine | 46,408 | 69,656 | Putrescine2spermidine E. rectale | SPRM | 100%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 14.1 | PFOR_II_pathway | SCFA | 19,854 | 43,390 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%
Region 23.1 | Others_HGD_unassigned | Putative | 86,064 | 108,076 |
Region 24.1 | Acetyl-CoA_pathway | SCFA | 5,590 | 39,720 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 61%
Region 28.1 | Rnf_complex | E-MGC | 8,249 | 33,260 | Rnf complex C. sporogenes | RNF | 100%
Region 31.1 | Fumarate2succinate | SCFA | 32,100 | 55,439 |
Region 43.1 | Rnf_complex | E-MGC | 12,688 | 36,818 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 14%
Region 47.1 | GR_eut-pdu-related | Putative | 1 | 24,150 | Trimethylamine synthesis C. sporogenes | TMA | 50%
Region 56.1 | succinate2propionate | SCFA | 86,235 | 106,231 | Succinate to propionate B. theta | PRO | 33%
Region 71.1 | Pyruvate2acetate-formate | SCFA | 1 | 12,183 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%
Region 89.1 | Others_HGD_unassigned,TPP_AA_metabolism | Putative | 1 | 23,738 |
Region 89.2 | Others_HGD_unassigned | Putative | 49,728 | 72,671 |
Region 111.1 | Putrescine2spermidine | Aliphatic_amine | 46,408 | 69,656 | Putrescine2spermidine E. rectale | SPRM | 100%

No primary metabolite regions were found in these records:
  c00001_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_1)
  c00002_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_2)
  c00003_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_3)
  c00004_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_4)
  c00005_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_5)
  c00006_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_6)
  c00007_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_7)
  c00008_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_9)
  c00010_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_10)
  c00011_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_11)
  c00012_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_12)
  c00013_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_13)
  c00015_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_33)
  c00016_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_44)
  c00017_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_55)
  c00018_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_61)
  c00019_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_62)
  c00020_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_63)
  c00021_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_64)
  c00022_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_65)
  c00025_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_68)
  c00026_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_69)
  c00027_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_70)
  c00029_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_72)
  c00030_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_73)
  c00032_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_75)
  c00033_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_76)
  c00034_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_77)
  c00035_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_78)
  c00036_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_79)
  c00037_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_80)
  c00038_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_81)
  c00039_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_82)
  c00040_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_83)
  c00041_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_84)
  c00042_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_85)
  c00044_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_87)
  c00045_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_88)
  c00046_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_89)
  c00048_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_91)
  c00049_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_92)
  c00050_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_93)
  c00051_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_94)
  c00052_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_95)
  c00053_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_96)
  c00054_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_97)
  c00055_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_98)
  c00057_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_100)
  c00058_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_101)
  c00059_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_102)
  c00060_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_103)
  c00061_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_104)
  c00062_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_105)
  c00063_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_106)
  c00064_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_107)
  c00065_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_108)
  c00066_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_109)
  c00067_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_110)
  c00068_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_111)
  c00069_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_112)
  c00070_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_113)
  c00072_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_115)
  c00073_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_116)
  c00074_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_117)
  c00075_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_118)
  c00076_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_119)
  c00077_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_120)
  c00078_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_121)
  c00079_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_122)
  c00080_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_123)
  c00081_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_124)
  c00082_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_125)
  c00083_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_126)
  c00084_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_127)
  c00085_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_128)
  c00086_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_129)
  c00087_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_130)
  c00088_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_131)
  c00090_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_133)
  c00091_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_134)
  c00092_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_135)
  c00093_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_136)
  c00094_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_137)
  c00095_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_138)
  c00096_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_139)
  c00097_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_140)
  c00098_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_141)
  c00099_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_142)
  c00100_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_143)
  c00101_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_144)
  c00102_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_145)
  c00103_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_146)
  c00104_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_147)
  c00105_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_148)
  c00106_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_149)
  c00107_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_150)
  c00108_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_151)
  c00109_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_152)
  c00110_gnlPro.. (original name was: gnl|Prokka|HHJFGIKK_153)

Compact view
c00014_gnlPro.. - Region 1 - PFOR_II_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 19,854 - 43,390 nt. (total: 23,537 nt) Show pHMM detection rules used
PFOR_II_pathway: cds(POR and POR_N and PFOR_II and EKR and Fer4_16 and TPP_enzyme_C)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00023_gnlPro.. - Region 1 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 86,064 - 108,076 nt. (total: 22,013 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00024_gnlPro.. - Region 1 - Acetyl-CoA_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 5,590 - 39,720 nt. (total: 34,131 nt) Show pHMM detection rules used
Acetyl-CoA_pathway: (CdhC and CdhD and minimum(8, [CbiA, FTCD_C, FTHFS, FeS, Fer2, GCV_H, MTHFR, MTHFR_C, Prismane, Pterin_bind, Pyr_redox_2, Pyr_redox_dim, RACo_C_ter, THF_DHG_CYH, THF_DHG_CYH_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00028_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 8,249 - 33,260 nt. (total: 25,012 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00031_gnlPro.. - Region 1 - Fumarate2succinate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 32,100 - 55,439 nt. (total: 23,340 nt) Show pHMM detection rules used
Region on contig edge.
Fumarate2succinate: (Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or Fer4_7 or SucD_FumR))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00043_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 12,688 - 36,818 nt. (total: 24,131 nt) Show pHMM detection rules used
Region on contig edge.
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00047_gnlPro.. - Region 1 - GR_eut-pdu-related
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 24,150 nt. (total: 24,150 nt) Show pHMM detection rules used
Region on contig edge.
GR_eut-pdu-related: (minimum(1, [Gly_430_pcre, Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1, PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2, [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not EutC and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00056_gnlPro.. - Region 1 - succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 86,235 - 106,231 nt. (total: 19,997 nt) Show pHMM detection rules used
Region on contig edge.
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00071_gnlPro.. - Region 1 - Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 12,183 nt. (total: 12,183 nt) Show pHMM detection rules used
Region on contig edge.
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00089_gnlPro.. - Region 1 - Others_HGD_unassigned,TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 23,738 nt. (total: 23,738 nt) Show pHMM detection rules used
Region on contig edge.
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00089_gnlPro.. - Region 2 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 49,728 - 72,671 nt. (total: 22,944 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00111_gnlPro.. - Region 1 - Putrescine2spermidine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 46,408 - 69,656 nt. (total: 23,249 nt) Show pHMM detection rules used
Putrescine2spermidine: (minimum(2, [AdoMet_dc, Spermine_synt_N, Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.