LOCUS       gnlProkkaABBELFNK_61   15578 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ABBELFNK_61.
ACCESSION   gnlProkkaABBELFNK_61
VERSION     gnlProkkaABBELFNK_61
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 00:42:44
            Original ID  :: gnl|Prokka|ABBELFNK_61
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 31453
            Orig. end    :: 47031
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15578
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12091]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12091
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..15578
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15578
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             95..1246
                     /locus_tag="ctg29_39"
                     /transl_table=11
                     /translation="MEIIKDLPEVFEEFAEQRKNSFLAIKKIKDQNIPVIGSYCTYFPQ
                     EIAMAMGAASVGLCSMSDETIPVAEQTLPKNLCPLIKASYGFAVTDKCPFFYFSDVVVG
                     ETTCDGKKKMYEFMSEFKDVFILELPHKQTEAALQYWKSEIIRFKEYLEKKFEVEITEE
                     KLREAVRISNEGRRALKDFYELMKQDPAPMKGENLYNVLYGTTFKFDRSKVPAEIDALT
                     VKLKEEYAAGKNEGKKHRILITGCPMGGATMKVVKAIEENGGVVVAFENCSGAKSVDRL
                     IDENDPDIYEAIARRYLNIGCSVMTPNPNRFELLNELIDEYQVEAVVEMTLQACHTYNV
                     EAGKVGRFVREEKKIPYLHVETDYSQSDVGQLNTRIAALIEML"
     CDS             complement(1506..1619)
                     /gene="allorf_32959_33072"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_32959_33072"
                     /protein_id="allorf_32959_33072"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTCCLMVMNIRKALSAGKIHPTERASVFCPYFLVSGL"
     CDS_motif       complement(1569..1619)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MTCCLMVMNIRKALSAG"
                     /locus_tag="allorf_32959_33072_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1506..1568)
                     /prepeptide="core"
                     /locus_tag="allorf_32959_33072_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.50"
                     /molecular_weight="2210.6"
                     /monoisotopic_mass="2209.2"
                     /core_sequence="KIHPTERASVFCPYFLVSGL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTCCLMVMNIRKALSAG"
                     /leader_location="[1568:1619](-)"
                     /alternative_weights="2228.6"
                     /alternative_weights="2246.6"
     CDS             1711..4392
                     /locus_tag="ctg29_40"
                     /transl_table=11
                     /translation="MKSNYKIFTAVFLSAIMTAAAPLTVCGAEVFSAGESFSDGTGSIP
                     AILTDMVLPGGEIGTEYQVQLEADTDVSWSLEEGSELPAGLTLSSGGVISGTPQKEGSF
                     SFTVQADNGIGVSSQELSLYVAQREQEPVIKQYELTSGTALIDLGIHAEGEQSRKRLFL
                     YNAGTDSLHLSDFPQSRYFDFSYAPIFDTNTDEEMQPGSCAAVDIDDKKDLPAGNYEET
                     VTFETKEGASCKVTLKVIVGASSEKDYELSIETGTEEEFTESDFYDPEFRVEKYVVVRN
                     SGKKETRIRVDTSGLKNFEVDDQMAKWTEDYEEQDSKKLLKPGETLYFYILPKQEYGIY
                     DETFAFLADDGSRYPLHVTMNREKNPTEKKQLEITEKSAGAFPTMQWGYKTLPEAKTYI
                     LKNVTDTDMKLSFNRSKECSVSLSGNAYLAPGESTELRLLPKLGLSVGKYSFQVTVTAK
                     TVAGEHLTTQNLYNSFIVGDRTYQGLADAVEPVTGITNGAEKTADALHLPDWLEVYGAE
                     VDGKKTTFSASVKWDVEDCVYDPKSKAAQSFTVTGHLELNEDENNEGLDTAVQIMVQVD
                     AYQTLNRPVIDLLRTGVRTNYAMLYLRDLSNEADGYQFVTAKSQKDLKKGNYTAQTKIT
                     NSELNQYPELKYIPEGTHSLYCRAYKENSSHVMEYGEWSDGVPVTVKVKTPDAPVVQKV
                     QVKKNDVRIVLNSKGEEPDGYDVVAARSKNGKEPSDYIKVKSGYSGSSKELILRGVPAG
                     TWYIGVHAYKYLNGSNTKVLSKWAEVRKVTVKTSLVTGKPAVKSAKVSRQGTKRNVTVT
                     FTAPKSCDGTDWVLAKKVSKSDDGSYTGVSSYAYTKKNQTKTTVVFKSVKPGVYYLAGR
                     AYVKGYAKSYTKWSKIKKIVVK"
     CDS             4674..5438
                     /locus_tag="ctg29_41"
                     /transl_table=11
                     /translation="MKQKKIVIIMAGILAAAAAMTGCAEQNKTATQVDYTQNSQGKSEQ
                     TKQKTAEKSQPDKKQVNKSTSDGKENSNQTADKKTKVFASSNNAGDVQNSGNDADNTDD
                     SQNTDDSQNTYVDNNSSENNGSTGDGGNQIDQTADQAMIYDSEGNGRLISQADDGNWYD
                     SDGNCYGSWEDIGRAMDEDGVTDQDGNKYYWTWTAPDDASGKVRDPYDLYSWDPGTNSY
                     IPFQAAESDCSPIGRGNGWYYYDEDSGEYVPW"
     CDS             complement(5581..6468)
                     /locus_tag="ctg29_42"
                     /transl_table=11
                     /translation="MTKTEKAVTWAIEIANDPAHGYDQDNRWGPDYDCSSLVISAWQQA
                     GVPVKTKGAYNTKSMKSVFLSCGFKDVTSSVNLDNGSGMKRGDVLLNIARHTVMHIGNG
                     KVVSASINENGGAHGGTPGDQNGNEIKIQNYYNCPWDCVLRYNEDSTSTDPEPQPTTGN
                     AKIRKGQSYANKFANTGISITGKRDAATKKAAIKVLQTALNKDYGAGLDVDGIWGTNTS
                     NALGKHYVKSGETQYMVTAAEILLLLRAYDPNGVEIPGTFGSGLLSAVKAFQKAQGLTV
                     SGTCDRNTFLKLIS"
     CDS             complement(6656..6862)
                     /locus_tag="ctg29_43"
                     /transl_table=11
                     /translation="MPTIENLLKLSEILDVGLDYFLYDLLPHNKDIQSPAIQDAISIMN
                     QMGERQTEYIVKILKIYQASHQD"
     CDS             7110..7664
                     /locus_tag="ctg29_44"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTIREILKKTGKTREDFFPKGYLLGKRIKLTRSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKGDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             7670..8377
                     /locus_tag="ctg29_45"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKDITEQYFAEKNVDCTVTTYQNVEWFLL
                     GLNEEKFDMYILDIQMPGENGIEAAREIRRLYPDPVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKEKLLQAYDALLPGIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTVEKELNSKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGV"
     CDS             8381..9862
                     /locus_tag="ctg29_46"
                     /transl_table=11
                     /translation="MLKVLLYGLATFMETGIGVWIFSQTFSERRILEKKYYVLEWLLYS
                     LIFFGIYNFSVSLWQIDKKIEKYVIKVICIYIIGLIAGIIYDIFFVKKKEMVLRRILYI
                     GMIFWLTAQYWAGYQSLLMIILGSGIIVLYVFCYFDCTFKQAYVWNFFYAVNIGLIKEA
                     YVVYAGVFNHKQWDDFYSYPRGHTYQEVIFWILGCLFIFWIIKFILSVNSIKGILRTRL
                     KELFIIGLLEYVLLIVSIIYKFGTIKKENFVMTACLLAVSNIALIGVYVKFQKKTLEMR
                     NQILDMRCKLMEEEYEELRMSYDRYRCLVHDEKHLLLYIKECLENGELDSCITFLNHYK
                     RESIRYSGVAWTGIPEINFMLNIKVRKMEEKNIFFKVDSKIEKIPMKDIDFVVLLGNLL
                     DNAIEAAEKCEEGKGKITCIFRNINDMFIFKVKNTSIYKPYEKNTKFYTSKKEKDEHGW
                     GIESVKQIVRKYNGEIDFKYDKDFFEVEIIISDNT"
     CDS             9879..10007
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_47"
                     /transl_table=11
                     /translation="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYGTIVCC"
     CDS_motif       9879..9989
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /locus_tag="ctg29_47_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9990..10007
                     /prepeptide="core"
                     /locus_tag="ctg29_47_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="519.7"
                     /monoisotopic_mass="519.2"
                     /core_sequence="TIVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /leader_location="[9878:9989](+)"
     CDS             10001..12091
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     594; E-value: 8.8e-180)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_48"
                     /sec_met_domain="DUF4135 (E-value: 1.3e-93, bitscore:
                     305.9, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4e-13, bitscore: 40.6,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKLDYLCRKNRTMFLKILILDVHRQKNFGNLKGSTPKEQYDYYE
                     KKYLNNATYVKSLLQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRKF
                     SGTVGIYMSKGDIHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGISC
                     RTVRYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAHG
                     EYPVIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNRG
                     VLISAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYTE
                     CIIRGFCRAYMVTMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSREC
                     RKALLNVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLPC
                     TPYESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIYS
                     QIRKIVHRICSRAIIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLHD
                     FEEKNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGEGSVVCTYLYLFKLTG
                     KREWMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADMEK
                     DL"
     CDS             12161..12691
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_49"
                     /sec_met_domain="LANC_like (E-value: 5.5e-35, bitscore:
                     112.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHGNSGFMMAYAALYECNHKAEYADKIQLLLKYEDSLYSEKAGN
                     WKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLNAADSLFYGEQDEK
                     ICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAKISGTEYLNLAFMN
                     GISGTGMALMEIL"
     CDS             complement(12744..13268)
                     /locus_tag="ctg29_50"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILRYISENK"
     CDS             13569..13799
                     /locus_tag="ctg29_51"
                     /transl_table=11
                     /translation="METTVMNVAVSQGIWAVLAVFLLIYIVKSNEQRDTKQEEREKNYQ
                     TVIESLTEKFQILNQVQSDLKEIKDNLFNKN"
     CDS             14402..15577
                     /locus_tag="ctg29_52"
                     /transl_table=11
                     /translation="MYLKSRVKLPDVHGKLTRLRRGDITYIKYEYDRYYDPEKKYTYPQ
                     RATIGKVCPDDDTMMIPNEAFLKYFPDAVLSGMEDRTERSSCLRVGTYAVMHKIVLDYS
                     LDKLLGQFFSERDMALLLDLASYSIVEESNVAQHYPDYAYNHPLYSSGMKIYSDASVSD
                     FFKSITKDKSTGFLNEWNAKRNRRERIYISYDSTNKNCQAGEIELAEFGHAKTDIGSAI
                     VNYSVGYDLKNKEPLFYEAYPGSINDVSQLRTMLGKITGYGYKKIGFILDRGYFSRGNI
                     RYLDECGYSFVIMAKGMSSFINDLILENKGTFENKRSCDMNAYGVYGKTVQRTLFEGDE
                     KKRYIHIYHSISKDADEREHFENALRERTALLMSHQNETVEFGSAYEKYFYL"
ORIGIN
        1 caactgtaga ggataataag gactgcaaca gttggcgaat ggtatgaaag aagtaaaaaa
       61 taatataaaa acgatagaaa gatgaggtac aaagatggaa ataattaaag atttaccaga
      121 agtatttgag gagtttgcgg agcagaggaa gaattcattt cttgctatca agaagattaa
      181 ggatcagaat atcccggtaa ttggttctta ctgtacatat tttccacagg agattgcaat
      241 ggccatggga gctgcttctg taggtttatg ttccatgtct gatgaaacaa tcccggtagc
      301 cgagcagaca ttgccgaaaa atctctgtcc actgatcaag gccagttatg ggtttgcagt
      361 gacagataaa tgtccattct tttatttttc agatgttgta gttggtgaga ctacctgtga
      421 cggaaagaaa aaaatgtatg aatttatgtc cgaatttaag gatgtattta ttctggagct
      481 tcctcataaa cagacagagg ctgcacttca gtactggaag agtgagatta tccgtttcaa
      541 agaatatctg gagaagaaat ttgaggtgga gatcacagag gagaagcttc gtgaggcagt
      601 ccgcatcagc aatgagggac gtcgtgcttt gaaagatttc tatgaactga tgaaacagga
      661 tccggctcca atgaagggtg agaatcttta taatgtattg tatggaacta cctttaagtt
      721 tgaccgttcc aaagtcccgg cagagattga tgcactgaca gtgaagctga aagaagaata
      781 tgcagcaggc aaaaacgaag gaaagaaaca tcgtattctg atcaccggat gtccaatggg
      841 cggagctacc atgaaagtag taaaagcaat tgaagaaaat ggcggtgtgg tagttgcttt
      901 tgaaaactgc tccggtgcaa agagcgtaga cagactgatt gatgaaaatg atccggatat
      961 ttacgaagca attgcaagac gttatctgaa tatcggctgt tctgttatga ctccgaatcc
     1021 gaaccgtttt gaactgttaa atgaactgat cgatgagtac caggtagaag ctgttgtgga
     1081 aatgactctt caggcctgtc atacttataa tgtggaagcc ggtaaagttg gcagatttgt
     1141 aagagaagag aaaaagattc cttatctgca tgtggagaca gattattctc agtctgatgt
     1201 tggacagcta aatacacgta ttgcggctct gatagaaatg ttataactgt gaaggtatta
     1261 taagattata cgaaaaatgt cgaattgtat gtattttatt atagcaatcc tttgaaataa
     1321 tgcatcttaa tccagcccat cagagtgtga aatcctgcgt cagatatctt tgccgtgcgt
     1381 cagcgcgcct gcagatatct tccttgtctt tcgcgctctg ctgaactgtc ttaaatgcat
     1441 tatttacgag gattgctata gaaaaaaata tgtataagca ataaatgaca agcgactgat
     1501 caaatttata aaccagaaac taaaaaatat ggacagaaaa cagaagctct ctctgtggga
     1561 tgaatttttc cggcggacag ggcttttctg atattcatga ccattagaca acatgtcatt
     1621 ccgtaattac agaaacattc ccgtccagtg gtatattaat attaattagg taaattgata
     1681 cttttatatt ttattatctg gaggagaaga atgaaaagta attacaaaat ttttacagca
     1741 gtttttttat cggcaattat gacagcagca gctccgttaa cagtatgcgg ggcggaagtt
     1801 ttttcggcgg gagaatcttt cagtgatgga acagggagta ttcctgccat attgacagat
     1861 atggttctgc cgggtggaga gattggaaca gaatatcagg tacagcttga agctgataca
     1921 gatgtgagct ggagtctgga ggagggaagc gagcttccgg cgggacttac gttgtcttcc
     1981 gggggagtga tcagcggaac accgcagaag gaagggagtt tcagctttac tgtacaggcg
     2041 gacaatggta ttggagtttc ttcacaggaa ctgagccttt atgttgcaca gcgtgagcag
     2101 gaacctgtta taaagcagta tgagctgaca tcaggtactg ctttgatcga tctgggaatt
     2161 catgcagagg gagaacagtc acgtaagcgg ttatttcttt ataatgcagg aacagattcg
     2221 cttcatctct ctgattttcc gcagagcaga tattttgatt tttcctatgc accgattttc
     2281 gatacaaata cggatgaaga aatgcagccc ggaagttgtg cggctgtgga cattgatgat
     2341 aagaaggatc tgcctgccgg aaattatgaa gagacagtga catttgagac aaaagaaggt
     2401 gcttcctgta aggttactct gaaagtaatt gtgggagctt cctctgaaaa agattatgag
     2461 ctgagtatag aaacaggtac agaagaagag tttacagaaa gcgatttcta tgatccggaa
     2521 tttcgtgtgg agaagtatgt agtagtcaga aattcaggga aaaaggaaac cagaatacgg
     2581 gtagacactt ccggtcttaa gaactttgaa gtagatgacc agatggcaaa gtggacagaa
     2641 gattatgagg aacaggattc caaaaagctg ctgaaaccgg gagaaacgct ttatttttat
     2701 atattgccga agcaggaata cggaatttat gatgaaacgt ttgcatttct cgcagatgac
     2761 ggaagcagat atcctcttca tgttacaatg aacagagaga agaatccgac agaaaagaag
     2821 cagctggaaa ttactgaaaa gtctgccggg gcttttccga caatgcagtg gggttataag
     2881 acacttccgg aagcaaagac atatattctg aaaaatgtta ctgacacaga tatgaagctg
     2941 tcttttaacc gcagtaaaga atgcagtgtg tcattgtccg gaaatgctta tctggcacct
     3001 ggggagagca cagaactgag actcttgcca aaactggggc tttcggtggg aaaatatagt
     3061 tttcaggtga ctgtgactgc gaaaacagtg gcaggagaac acctgacaac gcagaatctg
     3121 tataattctt ttattgtagg agaccggact tatcagggac tggcagatgc tgttgagcct
     3181 gtgaccggaa ttaccaatgg tgcagaaaaa acagctgatg ctttgcatct gccagattgg
     3241 ctggaagttt atggtgccga ggtggatgga aagaaaacaa cattttctgc atctgtgaag
     3301 tgggatgtgg aggattgtgt gtatgatccg aaaagcaagg cagctcaaag ttttacagtg
     3361 accggtcatc tggaactgaa tgaagatgaa aataatgaag gactggacac tgctgtgcag
     3421 ataatggtac aggtggatgc atatcagaca ttaaacagac cggttattga cttattgaga
     3481 accggagtga gaacaaatta tgcaatgctt tatctgagag atctttccaa tgaagcagac
     3541 ggctatcagt ttgtgacagc caaatctcag aaggatctga aaaaggggaa ttatactgcg
     3601 cagacaaaaa ttacaaattc tgaactgaat caatatcctg agctgaagta tattccggag
     3661 ggaacacata gtctttattg cagggcatac aaagagaaca gcagccatgt tatggaatat
     3721 ggggaatggt cagacggggt tccggttacg gtaaaggtaa agactccgga cgcacctgtg
     3781 gttcagaagg tgcaggtgaa aaaaaatgat gtcagaatag tacttaacag caagggtgag
     3841 gaaccggacg gttacgatgt tgttgctgcc agaagtaaga acggaaaaga accatcggat
     3901 tatataaagg taaagagtgg gtattccgga agcagtaaag agcttatctt acggggcgta
     3961 ccggcaggaa cgtggtatat tggcgtacat gcttataaat atctgaatgg gagcaatacc
     4021 aaagtgctca gtaaatgggc agaggtcagg aaggtaactg taaaaacaag ccttgtaaca
     4081 ggaaaacctg ctgttaaatc agctaaggtt tccagacagg gaacaaaaag aaatgtaacg
     4141 gtgacgttta ctgctccaaa gtcctgtgat ggaacagact gggtactggc aaagaaagtt
     4201 tccaaatctg atgacggcag ctatacaggt gtaagcagtt atgcttatac aaagaaaaat
     4261 cagacaaaaa ccacggtggt ctttaaaagt gtgaagcccg gagtctacta ccttgcagga
     4321 cgtgcctatg taaaaggcta tgcaaaaagt tatacgaaat ggtcgaaaat aaagaaaata
     4381 gttgtgaaat aagcactgct gtcatttgtt tcacagagat ttcactttta agaagaaaaa
     4441 tccccctttt accaggcgtt tatacctgct ttttcctgta atactcaaag tttacggtac
     4501 tgccacttat tatactcaaa ttttgtctga atttggagat aaataatgtc ctttttatga
     4561 cagataaggg acatatgagg catcaaagcc tgtggagtat gtaataatga acaggaaaag
     4621 cacattatga taaaggcaat gacattttta gtaaatgtag aaaggacaac aaaatgaagc
     4681 agaaaaagat tgtaattatt atggcaggga ttttagcagc agcggctgct atgacgggct
     4741 gcgcggaaca gaataaaaca gcgacacagg ttgattatac gcagaactca caggggaaat
     4801 ccgaacagac aaaacaaaaa acagcagaaa aatctcagcc ggataaaaaa caggtaaata
     4861 aaagtacatc cgatggaaaa gaaaattcaa atcagactgc ggataagaag acgaaagtat
     4921 ttgcctcatc caataatgcg ggcgatgtac agaattcagg gaatgatgcg gataatacag
     4981 atgattcaca gaatacagat gattcgcaga atacatacgt ggacaataat tcatctgaaa
     5041 ataatggctc aacaggcgac ggtggcaatc aaattgatca gacagcagat caggcgatga
     5101 tatatgacag tgagggaaat ggaagactga tttctcaggc tgacgatgga aactggtatg
     5161 acagtgacgg aaattgttat ggaagctggg aggatattgg gcgtgctatg gatgaagatg
     5221 gtgttacgga tcaggatggc aataaatact actggacctg gactgcacct gatgatgcat
     5281 caggaaaagt aagagatccg tatgacctgt attcctggga tccgggaacc aattcctata
     5341 taccgtttca ggctgcggaa tctgactgta gtcctatagg cagaggaaac ggctggtatt
     5401 attatgatga agacagcggc gaatatgttc cgtggtaaaa aataagaaaa caaaagaaac
     5461 agttttgaaa tcattttgat gggtttcaaa actgtttctt tttatataca agaaatagtg
     5521 aaggggcata tccggcagaa tcagtgaaaa gaattctgcc ggatgtttat ctggtaaaga
     5581 tcagctgatc agtttcagga aagtatttct gtcacaggtt ccggaaaccg ttaagccctg
     5641 tgccttctgg aatgccttta cagcagagag aagtcctgag ccaaaggtac cgggaatctc
     5701 tacaccgttt ggatcataag cacgtaaaag aaggagaatc tcagcggcag ttaccatata
     5761 ctgggtttca ccgcttttta cgtaatgttt accaagggca ttgcttgtgt tagttcccca
     5821 gataccgtct acatccagac cggcaccata atctttgttc agagctgtct gaagaacttt
     5881 aatagctgct ttcttagtgg cagcatctct tttcccggta atggagatgc cagtattggc
     5941 aaatttattg gcataactct gacctttgcg gattttggca tttccagtag ttggctgtgg
     6001 ttctggatcc gtagatgtag aatcttcatt ataacgaaga acacaatccc acgggcagtt
     6061 gtagtaattc tggattttaa tttcgttgcc attctggtca cccggagtac caccgtgggc
     6121 tccaccattt tcatttatac tggcagaaac tactttgccg ttgccgatat gcataactgt
     6181 atggcgtgca atgtttaaca gtacatcacc gcgtttcata ccgcttccgt tgtcaagatt
     6241 aacactggaa gtaacgtctt tgaatccgca agacaggaaa acagacttca tacttttggt
     6301 attataagct ccttttgttt ttacaggaac accagcctgc tgccatgcgg agattaccag
     6361 tgaagaacaa tcgtagtccg gtccccatct gttatcctga tcatatccgt gtgccggatc
     6421 gtttgcgatt tcaattgccc atgttactgc tttttctgtt tttgtcattt ttttatcctc
     6481 ctgaaatttg attatttatt tgctcaccgg tgatacatct tataaagagt gagaaaaggg
     6541 aaaaatgtaa acatgaaaca gaaaaaaata aaaagcattt cctgattgtt gcttcgaggt
     6601 cagaaaaatg cttttcgagg acaaaaacac gaaaattgtc gaattgtaat tatatttaat
     6661 cctgatgaga ggcctggtat attttcagta tttttacaat gtattcagtc tggcgttcac
     6721 ccatttgatt catgattgaa attgcatcct gaatagccgg gctttgaata tctttattat
     6781 gaggaagcag atcataaaga aaatagtcaa gtcccacatc aagaatttca gaaagcttaa
     6841 ggagattttc gatagtaggc atatacttac ctgtttcaat ccggctgatc gtacttacag
     6901 ataaaccact taattcttcc aggtgttcct gagtaatatg tttattgatc cgagcttctg
     6961 caattctttt tccgatagta ttgtttttta taaataaaaa tcctttcctt tgataaagtt
     7021 tatcagacgg aattaaatat gtataaggat ataaatgaca agcgactaat caaatttgat
     7081 atgttttatg acaggaggaa tataggaata tggacgaata tacaaaggat ttgtatacca
     7141 tgatgttttc gttgcagact ttgcaaaatc agggaattac aatcagagaa actgtatata
     7201 aaagtctgga caaattactg ttatggaata aagaatctga aaacagtaaa tatctcgaat
     7261 tagcgttgct tcatatgcag gcttatgcta atatgggatt tgctttagat gaagaaaata
     7321 agacaatacg tgagatatta aaaaagacag gaaagaccag agaagacttt ttcccgaaag
     7381 gatatcttct tggaaagaga attaaactga ccaggtcaca ggttcgtggt atgattggaa
     7441 gatggagacc ttccagagac agtccgatga caatcggaga actggtggat gatatcatca
     7501 gaaaggtaaa aaaccatgag gaaggcagat acatttatca gtatcacaga actgatgtga
     7561 caaccaaagg ggatatcgag gtttatgagc tggtcatcaa taaggatgaa agttattttt
     7621 atgatgtgaa gaaattcaga ttttatacat tcatggagga ataattgcta tgataagaat
     7681 aatgattctg gatgatgacg aaatgtatct gaaaaaagaa aaggatatca cagaacagta
     7741 ttttgcagag aaaaacgtag attgcacggt aacgacatac cagaatgtgg aatggtttct
     7801 gctgggattg aatgaagaaa aattcgatat gtatattctg gatatccaga tgcctggaga
     7861 aaacggaata gaggcagcga gggaaattcg cagactttat ccggatccgg ttattatatt
     7921 tattacaaat tttgtggatt atgcaataga agcatatgag gtaaacacct atcgttatat
     7981 tcccaaagag tgtctgaagg aaaaacttct gcaggcttat gatgcgcttc ttcctggaat
     8041 tatggagaaa gaagagcggt actatatcat aaataaaaga aatgaagttg aaaaactggc
     8101 atattctgat attttctata tgaaaaaaga aggaaaatat gtgatttttg tgcacaggcg
     8161 tggggaagta aagatcagag caagtctgtc aacagtagaa aaagaactga attcaaaaga
     8221 atttattata tctgacagag gatatcttgc aaacatccaa catgtgatga agatgaaagg
     8281 aagggatctt tatatgcggg acggtaatat tattacagtt ggcagagaaa gattcaaagg
     8341 tgtcagagaa gcaattctga attactgggg ggtatgaaga atgctgaaag ttttattgta
     8401 tggactggca acgtttatgg agacagggat aggtgtctgg atatttagcc agacgttttc
     8461 tgaacgaaga atattagaaa aaaaatatta tgttctagaa tggctgttgt attctttgat
     8521 tttttttgga atttataatt tttctgtttc attatggcag attgataaaa aaatagaaaa
     8581 atatgtcata aaagttattt gtatatacat aattggatta attgcaggaa ttatatatga
     8641 tatttttttt gtaaagaaaa aggagatggt cttaagaaga atattatata tcggcatgat
     8701 attttggtta actgctcagt attgggctgg atatcaatcg ttgttaatga ttattcttgg
     8761 gagtggaata attgtattat atgttttttg ctactttgat tgcacattta aacaggcata
     8821 tgtttggaat tttttctatg cagttaatat aggattgata aaagaggctt atgttgtata
     8881 tgcaggggtg tttaaccata aacagtggga tgatttttat tcatatccga gaggacatac
     8941 atatcaggaa gttatatttt ggattttagg ctgtttattc atattttgga taattaaatt
     9001 tattttgtca gtaaacagta taaaaggaat attgcgtaca cgtctgaagg aactttttat
     9061 tattggattg ttagagtatg ttttattaat agttagcatc atatacaaat ttggtacgat
     9121 taaaaaggaa aattttgtaa tgaccgcatg tttattagca gttagtaata tagcattgat
     9181 tggtgtatat gttaagtttc aaaaaaagac cctagaaatg agaaatcaga ttttagatat
     9241 gagatgcaaa ttaatggaag aagaatatga agaattgaga atgtcatatg accggtatcg
     9301 gtgtttggtg cacgatgaaa aacatttgct tttatatata aaagaatgcc tggaaaatgg
     9361 agaactggat tcatgtatca cttttttgaa tcattacaag agagaaagca ttagatatag
     9421 tggagtagcg tggacaggaa ttccagaaat aaattttatg ttgaatataa aagtgcgaaa
     9481 aatggaagaa aagaatattt tttttaaagt agattcaaaa atagaaaaaa ttccgatgaa
     9541 agacatagat tttgttgtac tcctaggaaa tcttttggat aatgcaatag aagctgctga
     9601 aaagtgtgaa gagggaaaag gtaaaattac gtgtattttt cgaaatatta atgatatgtt
     9661 tatttttaaa gtaaagaata caagcatata taaaccttat gaaaaaaaca ctaaatttta
     9721 tacaagtaaa aaagagaaag atgagcacgg atgggggatt gaaagtgtca aacaaattgt
     9781 aagaaagtat aatggtgaaa tagattttaa atatgataaa gatttttttg aagtagaaat
     9841 aataattagc gataatacat aatgggagag tgacggttat gaacgaaatg aatgataaaa
     9901 taataggaaa tgtggaaaaa gaattagatg aaatagagat aatagatacg gaaagtatag
     9961 aagagaaatt gtcttttatt gtatatggaa ctatagtgtg ttgctgaaat tggattattt
    10021 atgcagaaaa aatcgaacta tgtttcttaa aatattaatc ttagatgtac atcggcagaa
    10081 aaattttgga aatctaaaag gaagtacgcc aaaagaacaa tatgattatt atgaaaaaaa
    10141 atatcttaac aatgcaacat atgtaaaatc tttactgcag gaatatcccg agttaaaacg
    10201 tctgcttgaa ttgaaaaata actctatcca gagagcagaa tgtgaaatca ggaaatctct
    10261 ttatgcagaa aaagaacaga tacaaaaaat attctgtgat ggaagaaagt tttccgggac
    10321 tgtgggaatt tacatgtcga aaggcgatat acacagagga ggacgaagtg tggcgaaggt
    10381 agaattggat aatggaacaa ttctgtacta taagccacat agtcttgata agaatataaa
    10441 atatcaggaa ctttataact atttatgcag aaaaacagga atttcctgca ggacggtacg
    10501 gtatttatct catgattcct atgggtggga agaaaaaatt gagaatatcc cctgtaaaaa
    10561 cgaaagtgag gtggagcatt attatttcag aatgggcata catctgtttt tgggatatgc
    10621 cctcggagca acagatcttc atggtgaaaa tattatcgca catggagaat atcctgtgat
    10681 tatcgatatg gagacatatc cgggatattt aaaacaacaa tcagagaaag acggaagtag
    10741 tgtagaagaa aaaataaaca aaagtacaga gataaaattg gcaaattcgg ttatacatac
    10801 aggaatgctt cctgttctca catggggcag aggaaacaga ggagttctta taagtgcaat
    10861 gggaacagag gaaaagataa aaacaccgtt taaacttcct gtggtaaagg atgataaaac
    10921 atctgatatc cacatagaat atgaacctgt ggaaatgcag ataaaggaat gcattgtaag
    10981 actaaatgat caggttatca atgcggcaga ttatacggaa tgcattatca gaggattttg
    11041 cagagcgtac atggtgacaa tggcagataa gaaagtggag gtgatgttgt ccggcttttt
    11101 tgacggacgt tccagagttg tactgcggca tacccaacag tatgcaatgt atcttatggc
    11161 ttcgtttcat ccggattata tgaagtcaag agaatgcagg aaagctcttt tgaatgtgat
    11221 tcacaaagag ggggaatctt cttttatgaa agagattcat gattatgaaa ttgacagcct
    11281 tctggaaatg gatatacctt gctttgagat tgatgcgaac agcagatctg tttatgatgg
    11341 aaatggcgga gaacataaag aatatctgcc ctgtactcct tatgagtcat ggcgaatgca
    11401 tatgaagcag atgagttact ctgatatgga atgtcagtgt gattatatca ggctgtccat
    11461 ggaaatgctg aaggcatctg atggaaagaa aaagatgttt ccgaccagga taaagggata
    11521 tgacacagat aaagagcgca aaatatacag tcagatcaga aagatagttc atcgaatctg
    11581 cagcagagca attatccggg aacagagcgc cggctgggcg ggtctgcaat tctgggataa
    11641 tggtcactgg aatctcagat caggtggaat atatttatat gatggaatat ccgggatagt
    11701 cttgtttctt gcaaaatatc ttcatgattt tgaagaaaag aatgcaagtg cagaagaaat
    11761 ttatcatctt gctgttttga gattgaaagc ttatacagat gaaatacaca aaaaacagat
    11821 ttatgataaa aatcttctga caggtattgt gaatggagaa ggttctgtgg tgtgtactta
    11881 tctttatctg tttaaactta caggcaaaag ggagtggatg atttatgcag aaaagcattt
    11941 cagcattatt gagagggtat ggaaagaaga ttcacaactg gattatctga gcggaaatgc
    12001 cggagctatt gtagtggcag tgatgttata taaagaaacc ggaaatctga aatattatga
    12061 aatagcggca gatatggaaa aagatttgta gaagaaagga caggaaaccg gaaatggata
    12121 cggatggaga ttaaaaggaa cagacggacc gctggctgga atgtctcatg gcaacagtgg
    12181 atttatgatg gcttatgcag cgttgtatga atgtaatcat aaagcggaat atgctgataa
    12241 aatacagctt ttgctgaaat atgaagattc tttgtactca gagaaagccg gaaactggaa
    12301 ggatttacga gagagttcag gggaaagctt catgaatgca tggtgccatg gggcgccggg
    12361 aatcctgctt tcacgaatga aactggagga gctgtttcct gaggatatgc agattaaaaa
    12421 agacaggtta aatgctgcag actctttgtt ttatggagaa caggatgaaa aaatttgtct
    12481 gtgtcatggg atgtccggga atttacttat tatgaagaag tatcttcgaa aatatggtaa
    12541 taaaaaaatg aaggagcaat atgaggcgtt atgtgactgc cttttatttc aactggatca
    12601 cccggcaaaa atatctggga cagaatatct gaatctggct tttatgaatg gcatttccgg
    12661 tacgggaatg gcattaatgg aaattttatg aaaactaagg gaacacctgc agactgtaaa
    12721 tttatggtca gcaggtgttt cttttatttg ttttcggaaa tatatctgag aattagtttc
    12781 ttcttcatcc gattgacgta ctggcgggac agcttcagtt tccgggcaat ctgggcatcg
    12841 cttttatcct gataaaagta catggacaga atttttctct ggacactgtc cgaagggtaa
    12901 gagttgatat atgcggttac atcataatag gtgtcatcaa aactgtcggg agcctgtaat
    12961 gaaacagaac aagaatcaaa atcatctttt tcaggttcgg aaagacaact gcggcaaagg
    13021 gaacgatatc tgttttcgac agaggtctgc atgtatctga tacattcacc ttctgaggat
    13081 gaagaactta aatatggcaa tgtctttaac aaagtaagat acaattcctg tgtggaatct
    13141 tcgcgttcca tgcagtgaat ccgggatgca tatcctttca caagcggttc catacgtttg
    13201 agaatttcac tgtctgaatc tgggatacca ttttgataat tttggataag ttctgtcagt
    13261 gttttcatag gtatctacct cctttttagg ggaagtagta agaaaactgc tgatcagaaa
    13321 ctaaaaaaga aaaaaatttg tgagtttaca aatggaagag aaaaaactct ttattaagtg
    13381 aggttgcaaa tttagatcag cgataggaga agaaatacat ggtaaaaaga gatttgcaaa
    13441 ataattgtag agaatagaaa tatgctttaa attaaaacgg taataataag attagaaaag
    13501 acttttagta gacaaaacat agaaaaagtt tgcataataa aagaagatta aggaaggagg
    13561 cagaaaccat ggaaacaacg gttatgaatg tggcagtttc acagggaatc tgggctgtgc
    13621 ttgcggtttt tcttctgatt tacattgtga aatcaaatga acagagggat acaaagcagg
    13681 aagaacgaga gaaaaattac cagacggtga ttgagagttt aactgagaaa tttcagattc
    13741 tgaatcaggt tcaaagcgat ctgaaagaga ttaaggataa tctttttaac aaaaattaaa
    13801 tagggaaaag aaaaaagcct tttctgcagg atatattttt ccagcggaga gggcttctgt
    13861 cattttaggt aagaaaatag gttaatttga gaaaaatatg tttactaaaa tggtagatga
    13921 atataagcat aacattcgtg tccattagaa tacttttaat cccagattta cagatgttcg
    13981 tatagtaaat ggtatattat gataataaaa cctgactttt gggtagtgta aaatagatta
    14041 aaaaaaatgg ccgcaatcca agtgtttatg cgagggtgta aaaattcttg tgtctatgga
    14101 aagtaaatct ttctgataag aaatagatat gtaaaatttt gctgtcgaat taatgattat
    14161 gcggctgtcg aatatatctt tgtacttaca gtattgccat gtaggaaaat tatatacatc
    14221 attttcgatt tttttgcatg acaagtaagg catcatgatt accttaactt ccaaaaatga
    14281 gtagccctaa cgaaaataaa attttaaaaa agcccgtatt tctgcggaaa ttattgcaaa
    14341 aatacgggtt gtgctgtaca ataaatttag ggctatataa acctgaataa aggaggcaaa
    14401 tatgtacctg aaatcaagag ttaagctacc ggatgtgcat ggaaaattga cccgattaag
    14461 acgcggggat atcacatata ttaagtatga gtatgatcgc tattatgatc cggagaaaaa
    14521 atatacctat ccacagagag cgactatagg caaggtatgt ccagatgatg acactatgat
    14581 gattcctaac gaagcctttc tgaaatactt tccagatgca gtcttatcag ggatggaaga
    14641 ccggacagaa cgtagcagct gtctgcgggt tggtacatat gctgtaatgc ataaaatagt
    14701 attggattat tcgttagaca agctgctcgg acagttcttc tctgagcggg atatggcatt
    14761 attgcttgac cttgcctctt actctattgt agaagaaagc aatgtggcac agcattatcc
    14821 ggattacgca tacaatcatc cactgtatag ttctggtatg aagatctata gtgatgcgtc
    14881 ggtaagtgat ttctttaaga gcatcaccaa ggataagagt acaggctttc tgaatgaatg
    14941 gaatgcaaag agaaatcgaa gggagcgtat ttatatttcc tatgattcta cgaataagaa
    15001 ctgtcaggcc ggagagattg aactggctga attcggtcat gccaagacag atatcggttc
    15061 agctatcgtc aactattcgg ttggatatga tcttaagaat aaagaaccac tcttttatga
    15121 agcctatcct ggaagtatta acgacgtatc acagcttagg accatgcttg gtaaaatcac
    15181 tgggtatggc tataaaaaaa tcggtttcat tttggacagg ggatatttca gccgtggaaa
    15241 tatacgctat ttagacgaat gtggttatag ttttgtgatc atggctaaag gcatgtcttc
    15301 tttcataaat gatttgatct tagagaacaa aggaacgttc gaaaataagc gctcttgtga
    15361 catgaatgcc tatggtgtgt atggaaaaac agtacaaagg actttatttg aaggcgatga
    15421 aaaaaagaga tacattcata tttatcatag tatttcaaaa gatgctgatg aacgggagca
    15481 ttttgaaaac gcactgagag agcggacagc tttgctgatg tcacatcaga atgaaacagt
    15541 agagttcggt tcagcttacg aaaaatactt ttatcttc
//
