LOCUS       c00057_gnlPro..         9386 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ABBELFNK_93.
ACCESSION   c00057_gnlPro..
VERSION     c00057_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 03:54:23
            Original ID  :: gnl|Prokka|ABBELFNK_93
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9386
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9386
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5035:9277](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5036..9277
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..9386
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9386
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(152..1825)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ILVD_EDD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_1"
                     /sec_met_domain="ILVD_EDD (E-value: 4.3e-230, bitscore:
                     753.5, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDAVKTGTQQAPHRSLFNALGMTKEEMDRPLVGIVSSYNEIVP
                     GHMNLDKITQAVKLGVAMAGGTPVMFPAIAVCDGIAMGHVGMKYSLVTRDLIADSTEAM
                     AMAHQFDALVMIPNCDKNVPGLLMAAARLNVPTVFVSGGPMLAGHLNGHKTSLSSMFEA
                     VGAYAAGKLDEDGLTECEMKTCPTCGSCSGMYTANSMNCLTEVLGMGLKGNGTIPAVYS
                     ERIRLAKHAGMQVMEMYRKNIRPRDIMTKEAILNALTVDMALGCSTNSMLHLPAIAHEI
                     GMDFDISFANEISAKTPNLCHLAPAGPTYIEDLNEAGGVYAVMNELNKKGLLHTECMTV
                     TGKTVGENIKDCVNLNPEVIRPIDNPYSQTGGLAVLKGNLAPDGGVVKRSAVVEEMMVH
                     EGPARVFDCEEDAIAAIKGGKIVEGDVVVIRYEGPKGGPGMREMLNPTSAIAGMGLGSS
                     VALITDGRFSGASRGASIGHVSPEAAVGGPIALVEEGDIISINIPELKLEIKVSDEEMQ
                     ARKAKWQPREPKVTTGYLARYAAMVTSGNRGAILEVPKAK"
     CDS             complement(1863..2945)
                     /locus_tag="ctg57_2"
                     /transl_table=11
                     /translation="MDYKIALIPGDGIGPEIVREAKKVLDKVCEKYGHSFSYSEVLLGG
                     ASIDVHGVPLTDEAIATAKSSDAVLMGSIGGDAKTSPWYKLEPSKRPEAGLLAIRKALN
                     LFANLRPAYLYNELRKACPLRDEIIGDGFDMIIVRELTGGLYFGERQTIEENGVKKAID
                     TLSYNENEIRRIAIKAFEIARKRRNKVTSVDKANVLDSSRLWRKVVEEVAKDYPDVTLE
                     HMLVDNCAMQLVRDPKQFDVILTENMFGDILSDEASMVTGSIGMLSSASLNETKFGLYE
                     PSHGSAPDIAGQDKANPIATILSAAMMLRFSLDMDKEADAVEAAVQKVLTEGYRTGDIM
                     SEGCKLVGTKEMGDLIAAAL"
     CDS             complement(3111..3410)
                     /locus_tag="ctg57_3"
                     /transl_table=11
                     /translation="MDASSGMGMVGAIVWMVVLFGIMYFLMLRPQKKEQKRLQAMLNDM
                     EVGDSIVTTSGFYGVIIDMTEEDVIVEFGNNKNCRIPMRKQAIAEVEKAGSAAE"
     CDS             complement(3468..3596)
                     /locus_tag="ctg57_4"
                     /transl_table=11
                     /translation="MMCSDALIRLLCMKTRFHTEGNGDYKWIAKQLFSMSSRQDGL"
     CDS             complement(3659..4810)
                     /locus_tag="ctg57_5"
                     /transl_table=11
                     /translation="MAEYKLLKTEGRAKRAEFHTVHGTIQTPVFMNVGTIGAIKGAVST
                     MDLQQIGTQVELSNTYHLHVRPGDKIVKQLGGLHKFMVWDKPILTDSGGFQVFSLAKLR
                     KIKEEGVYFNSHIDGHKIFMGPEESMQIQSNLASTIAMAFDECPSSVADRDYVQKSVDR
                     TTRWLARCKAEMARLNSLPDTINKEQLLFGINQGAVYEDIRIEHAKAISEMDLDGYAVG
                     GLAVGETHEEMYRILDAVVPYLPQNKPTYLMGVGTPANILEGVERGIDFFDCVYPSRNG
                     RHGHVYTNHGKMNLFNAKYELDTRPIEEGCQCPACQHYSRAYIRHLLKAKEMLGMRLCV
                     LHNLYFYNHMMEEIRDALDAGNFAEYKKMRLEGFEEGKINSKR"
     CDS             5036..9277
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_6"
                     /sec_met_domain="HGD-D (E-value: 5.2e-64, bitscore: 205.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 5.7e-38, bitscore:
                     119.8, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYKTLGIDIGSTTVKIAILDENENLIFADYKRHFANIQETLADL
                     LQEAFDQYGEMTLHPVITGSGGLTLANHLGVPFTQEVIAVSTSLQKLAPKTDVAIELGG
                     EDAKIIYFENGNVEQRMNGICAGGTGSFIDQMASLLQTDATGLNEYAKDYKALYPIAAR
                     CGVFAKTDIQPLINDGATKPDLSASIFQAVVNQTISGLACGKPIRGHVAFLGGPLHFLS
                     ELRESFIRTLKLDEEHTIIPENSHLFAAIGSALNAKEDNSISLTEMKDRLRNSIKLDFE
                     VERMEPLFASQEEYDAFAKRQSSYKVKTGDLATYKGNCYLGIDAGSTTTKTALVGEDGT
                     LLYSFYSSNNGNPLKTTIRSIKEIYELLPKDAKIAYSCSTGYGEALIKAALLLDEGEVE
                     TVSHYYAAAFFDPEVDCILDIGGQDMKCIKIRNKTVDSVQLNEACSSGCGSFIETFAKS
                     LNYTVQDFAKAAVFAQHPIDLGTRCTVFMNSKVKQAQKEGAEVSDISAGLAYSVIKNAL
                     YKVIKVSDASELGKHIVVQGGTFYNDAVLRSFEKIAGCEAIRPDIAGIMGAFGAALIAR
                     ERHQEGAETTMLSIDKINELKYTTSMANCRGCTNNCRLTINKFSGGRQYVSGNRCERGI
                     GKEKNKDHIPNLYEYKYKRIFSYAPLTADKATRGKVGIPRVLNMFENYPFWYTFFTELK
                     YEVVLSPTSTRKIYELGIESIPSESECYPAKLAHGHVTWLIRNGVKFIFYPCIPYERNE
                     FPDAVNHYNCPIVTSYAENIKNNVDELNDPSITFRNPFLAFTSEEILTNRLVEEFKDIP
                     AEEVKAAVHKGWEEMAAARRDVQKKGEETLKYLEDTGRHGIVLAGRPYHIDPEIHHGIP
                     DLINSYGIAVLTEDSISHLAPVERPIRVNDQWMYHSRLYAAANYVKTRDDLDLIQLNSF
                     GCGLDAVTTDEVYEILDGSDKIYTCLKIDEVNNLGAARIRIRSLIAAIRAKKAQGQKRT
                     VKPASIDKVSFTKEMRKDYTILCPQMSPFHFSLLQAAFNSCGYNLEVLPNDNKHAVDVG
                     LKYVNNDACYPSLIVVGQIMDALLSGKYDLNKTAVVMSQTGGGCRASNYIAFIRRALKK
                     AGMEQIPVISVNLSGLESNPGFKLTLPLVKKVAYGAVFGDILMKCVYRMRPYELEEGIV
                     NRKHKIWEQRVISFLSGSSISHSQFKKMCREMVHEFDTIPISDVKKPRVGIVGEILVKF
                     LPAANNHLAELLESEGAEAVVPDLIDFMCYCFYNQNFKVENLGFKKSKATMANWGIKAI
                     EWVRKPASEALAQSRHFAPPADIRDLAKMASPIVSTGNQTGEGWFLTGEMMELIHGDVP
                     NIVCIQPFGCLPNHIVGKGVIKEIRREYPTANIVAIDYDPGASEVNQLNRIKLMLSTAQ
                     KNLKKAEEKNA"
     CDS             9303..9386
                     /locus_tag="ctg57_7"
                     /transl_table=11
                     /translation="MYFTLQYIRLRACLKNKNCTKRMFYFPF"
ORIGIN
        1 tcctttcaat aatattctac tctaatatct tataaaactc aacatatact tatataattt
       61 tataatttat atttaactgt taattccctc ctaacttttc aggcaggaat cacaggttat
      121 gccgcaattc ccgccgggta cttgttcatc tttattttgc ttttggtacc tcaaggatcg
      181 ctcctctgtt tccggaggtt accatggcag catatcttgc aagatatcct gttgttacct
      241 ttggctcacg aggctgccat tttgcttttc ttgcctgcat ttcttcatcg gaaaccttga
      301 tctccagttt cagttccgga atgttaatac tgatgatatc cccttcttca acaagtgcga
      361 tcggtccgcc gactgctgct tccggtgata cgtgtccgat ggatgctcct ctggatgcac
      421 cgctgaaacg tccgtctgtg atcagggcta cagaagatcc cagtcccata cctgcgatcg
      481 cagatgtagg gttcagcatc tctctcatac caggaccgcc tttcggtcct tcataacgga
      541 taacaactac atcaccctca acgatcttgc cacctttgat agctgcgatt gcgtcttcct
      601 cgcagtcaaa gactcttgca ggtccttcat ggaccatcat ctcttctaca actgcagaac
      661 gttttacaac accaccgtcc ggtgcaaggt tacccttgag aactgcaagt ccgcctgtct
      721 ggctgtatgg attgtcaatc ggtctgataa cttcaggatt taagtttaca caatctttga
      781 tgttctcgcc tactgtcttg cctgtaactg tcatgcactc agtatgaaga agtcccttct
      841 tattcagttc gttcataact gcgtatacac cgcctgcttc gttcaggtct tctatgtatg
      901 taggacctgc aggtgcaagg tgacagaggt ttggagtctt tgcgctaatt tcgtttgcaa
      961 agctgatatc aaagtccatt ccgatctcat gagcgatagc cggaaggtga agcatactgt
     1021 ttgtggagca tccaagtgcc atgtctactg tcagggcatt gaggattgct tcctttgtca
     1081 tgatatctct tggacggatg ttctttctgt acatttccat aacctgcata cctgcatgtt
     1141 ttgcaagacg gatacgctcg gaatatacag cagggatggt tccgtttcct ttcagaccca
     1201 taccaagaac ctctgtcaga cagttcatgg agtttgctgt gtacataccg gaacaggatc
     1261 cgcatgtagg acatgttttc atttcacatt ctgtcagtcc gtcttcatca agcttgcctg
     1321 ctgcgtaagc acctactgcc tcgaacatac tggaaaggct tgtcttgtgt ccgttcagat
     1381 gtccggcaag cattgggccg ccgcttacga atacagtagg aacattcagt ctggctgctg
     1441 ccatcagaag tccgggtacg ttcttgtcac agttaggaat cattaccagt gcatcaaact
     1501 gatgtgccat tgccattgct tctgtggaat ctgcgatcaa gtctctggta accagagaat
     1561 atttcattcc aacgtgtccc attgcaatac cgtcgcatac tgcgattgcc gggaacataa
     1621 caggtgtacc gcctgccatt gccacaccaa gcttaactgc ctgtgtgatc ttgtcaaggt
     1681 tcatatgacc cggtacgatt tcattgtaag aacttacgat acctaccaga ggtctgtcca
     1741 tttcctcttt tgtcattcca agagcattaa acagggaacg gtgaggtgcc tgctgtgtgc
     1801 ctgtttttac tgcatcactt ctcattatct atttcctctt ttcttaattg tttatcattt
     1861 acttacagag ctgctgcgat cagatcgccc atctcttttg ttcctacaag tttgcatccc
     1921 tctgacataa tatcacctgt gcggtatccc tctgtcagga ctttctgcac tgctgcttct
     1981 actgcatctg cttctttatc catatcaagg gagaagcgaa gcatcattgc tgcggaaaga
     2041 atggttgcaa tagggtttgc cttatcctgt cctgcaatat caggtgcaga accatggctt
     2101 ggctcataga gaccgaattt tgtctcattt aagcttgcag atgaaagcat tccgatggag
     2161 cctgttacca tacttgcctc gtctgaaagg atatctccga acatattctc tgtcaggata
     2221 acatcgaact gtttcggatc acgtacaagc tgcattgcgc agttgtcaac cagcatatgc
     2281 tctaaggtaa catccggata atctttggca acttcctcta ccacttttct ccagagtctg
     2341 gaagaatcca gaacatttgc cttatctacg cttgttactt tatttcttct cttacgtgcg
     2401 atctcaaatg ctttgatggc aatacggcgg atttcgtttt cattatagga aagtgtatca
     2461 attgctttct tcacaccatt ctcttcaata gtctgacgtt ctccgaaata cagaccgcct
     2521 gtaagctcac gtacaatgat catgtcaaat ccgtctccga tgatctcatc gcggagaggg
     2581 caggcttttc tcagctcatt gtaaaggtaa gccggtctta agtttgcaaa aagatttaat
     2641 gccttacgga ttgcaagaag tcctgcttcc gggcgtttgg acggctcaag cttataccat
     2701 ggagaagttt ttgcatctcc gccaatagag cccatcagta cggcatctga tgatttggca
     2761 gtagcaattg cctcatcagt aaggggtacg ccgtgtacat cgatggatgc gccgcctaac
     2821 agaacttctg aataggaaaa gctgtgtcca tatttctcgc ataccttgtc cagtactttc
     2881 tttgcttctc ttacgatttc cggtccgatt ccgtcgccgg ggatcaatgc aatcttataa
     2941 tccataataa tttcctccaa aatactctaa ttgcgtaatt gttattataa taacgcactt
     3001 tccgacagat ttcaacctat taaagtgaaa aaatgcaaaa gtgccaatca aaaaagcaga
     3061 accacagtca tcactgacta tgtgttctgc tttttatcat ttcactttca ttattctgca
     3121 gcgcttccgg ctttctcaac ttcagcgatt gcctgttttc tcattggaat acggcagttt
     3181 ttgttgttac cgaattctac gatcacgtct tcctctgtca tgtcaatgat cacgccataa
     3241 aagccgctgg tagtaacaat gctgtcacca acttccatgt catttaacat tgcctgaagt
     3301 ctcttctgct cttttttctg agggcgaagc attaagaagt acataattcc gaacagtact
     3361 accatccaga caatagcgcc aaccataccc attccgcttg atgcgtccat tttgattcct
     3421 cctgtaactt ttcctgttat tctgcatatt tgcagtccat catgtattta cagaccgtcc
     3481 tgacggctgc tcatactgaa gagctgcttt gcgatccact tataatctcc gttaccttct
     3541 gtatgaaatc ttgttttcat gcataacaat ctgattaaag cgtcactaca catcatacac
     3601 aaaaaaccgc tttacttcaa gagtttttgg catatttaat aattatttta tatacagatt
     3661 atcttttcga gtttattttg ccctcttcaa agccttccag ccgcattttc ttatattctg
     3721 cgaagtttcc tgcatcaaga gcatctcgga tctcttccat catatgatta tagaaataca
     3781 gattgtgaag tacacagaga cgcattccca gcatttcctt tgctttcaga agatgacgga
     3841 tataggctct gctgtaatgc tggcatgcag gacactgaca gccttcttcg ataggacgtg
     3901 tgtccagttc atattttgca ttgaacagat tcatctttcc atgattggta tatacatgtc
     3961 catggcggcc gttacggctt ggatatacgc agtcaaagaa atcaattcca cgttcaacac
     4021 cttccaggat atttgccggt gttcccacgc ccatcaggta agtaggtttg ttctgaggaa
     4081 gataggggac taccgcatcc aggatcctgt acatctcttc atgggtttct ccaactgcca
     4141 gaccgccgac agcatagcca tccagatcca tttcagagat cgctttggca tgctcaatgc
     4201 ggatatcttc ataaacagca ccctggttga ttccgaacag aagctgctct ttgttaatgg
     4261 tatccggcag actgttcagt ctcgccattt ctgctttaca gcgggcaagc catcttgtgg
     4321 tcctgtctac agatttctgc acataatccc tgtcagccac actgctggga cattcatcaa
     4381 atgccatggc aatggtggag gcaagattgg attggatctg catactctct tccggtccca
     4441 taaagatctt atgcccgtca atatgggaat taaaataaac cccctcttct ttgatctttc
     4501 tcagctttgc aagggaaaat acctggaatc cgcctgagtc tgtaaggatt ggtttgtccc
     4561 ataccataaa tttatgaagg ccgcctaact gctttactat tttatcaccc ggacgcacat
     4621 gaagatgata agtatttgat aattctacct gtgttccgat ctgctgtaaa tccatggtgg
     4681 atacagcgcc tttaatcgca ccgatcgttc ccacattcat aaaaacagga gtctggatcg
     4741 taccatgcac tgtatgaaac tctgcacgtt tggcacgccc ctctgttttc agaagtttat
     4801 attctgccat attttctctc ctcttgataa aaatcacttt ttctattata tcccgaaata
     4861 gctgaatttt caactgcaaa taaggtaatc attggtaaag tttcatattg tcttttccag
     4921 accgttagcg tataatatta cggaatattc atatctggaa atagatattt taataggaaa
     4981 gaattacttc aatatttttt cttttataca gaaagaggag gcttgaattt actttatgaa
     5041 ttacaaaaca cttggaattg acattggttc cactactgta aaaatcgcga ttctggacga
     5101 gaatgaaaat cttattttcg cagattacaa gcgccatttc gccaacattc aggaaaccct
     5161 tgcagacctt cttcaggagg cctttgacca gtatggcgag atgactctcc atcctgtgat
     5221 cacaggttcc ggcggtctga cacttgccaa ccatctgggc gttcctttta cccaggaggt
     5281 tattgcagtt tctacttctc tgcagaagct ggcaccaaag acagatgttg ccatcgagct
     5341 tggcggtgag gatgccaaga tcatttattt cgaaaacgga aacgtagaac agcgtatgaa
     5401 cggtatctgt gcaggcggta ccggttcttt catcgaccag atggcttctc ttctccagac
     5461 agatgccaca ggtctgaatg aatatgccaa agattacaaa gcgctctacc cgattgctgc
     5521 acgctgcggt gttttcgcca aaacggatat ccagccactg atcaatgacg gtgcaaccaa
     5581 accggatctg tcagcttcta ttttccaggc agttgtaaac cagaccatct ccggtcttgc
     5641 ctgtggaaaa cccatccgtg gacatgttgc attcctgggt ggtccgcttc acttcctgtc
     5701 cgaactgaga gaatccttta tccgtacttt gaagctggat gaggaacaca ccatcattcc
     5761 ggagaactcc catctttttg cagccattgg ttctgcatta aatgcaaaag aagacaactc
     5821 catttccctg acagaaatga aagacagact ccgcaattcc attaagctgg atttcgaagt
     5881 agaacgtatg gaaccacttt tcgcttctca ggaagaatac gatgcatttg caaaacgtca
     5941 gagttcctac aaagtaaaaa caggagatct ggctacatat aaaggaaact gctatctggg
     6001 tattgatgca ggttccacca caaccaaaac tgcactggta ggcgaagatg gaacacttct
     6061 ctattccttt tacagcagca acaacggaaa cccgttaaaa actaccatcc gttctattaa
     6121 agaaatctat gaactgcttc ccaaagacgc aaagatcgct tattcctgtt ctacaggtta
     6181 cggcgaggct ctgatcaaag cggccctgct cctggatgag ggcgaggttg agaccgtatc
     6241 ccattactat gcagctgcat tctttgaccc agaggtagac tgtatcctgg atatcggcgg
     6301 acaggatatg aaatgtatca agatccgcaa caagaccgtt gacagcgtac agttaaatga
     6361 agcatgctcc tccggatgcg gttcctttat tgaaaccttt gccaaatccc tgaattatac
     6421 agtacaggat ttcgcaaaag ctgctgtttt cgcacagcat cctattgatc ttggtaccag
     6481 atgtactgtt ttcatgaatt ccaaggtaaa gcaggcgcag aaagagggag ctgaggtttc
     6541 cgatatttcc gcaggtcttg cttactctgt tatcaaaaat gctctgtata aggttatcaa
     6601 ggtttctgac gcttccgaac ttggcaagca catcgttgta cagggtggta ccttctacaa
     6661 tgatgcagtt cttcgaagct tcgaaaagat tgcaggctgt gaagccatcc gtccggatat
     6721 tgccggaatc atgggtgcct tcggtgccgc actgattgcc cgtgaacgcc atcaggaagg
     6781 cgcagaaacg actatgctct ccattgataa gatcaacgag ctgaaatata caacttctat
     6841 ggcaaactgt cgtggatgta ccaataactg ccgtctgact atcaacaaat tctccggcgg
     6901 ccgccagtat gtaagcggta accgctgtga acgcggtatc ggtaaggaaa agaacaaaga
     6961 tcatattccg aatctttatg aatataaata taagcgtatt ttctcctacg caccgcttac
     7021 tgctgataag gcaacgcgag gtaaagtagg tatcccccgt gttctgaata tgtttgagaa
     7081 ttatcctttc tggtatactt tctttacaga actgaagtat gaggttgtgc tctctcctac
     7141 ttccaccaga aagatttatg agctgggtat tgagtccatt ccaagtgaat ctgaatgcta
     7201 tcctgccaaa cttgcccatg gccatgtaac ctggctgatc cgcaatggcg tgaaatttat
     7261 tttctaccca tgtatcccat atgaacgtaa cgagttcccg gatgcagtca atcactataa
     7321 ctgcccgatc gttacctctt atgccgaaaa tatcaaaaat aacgtagacg aattaaatga
     7381 tccgtccatt accttccgca atccgttcct tgcatttact tctgaggaaa ttctgacaaa
     7441 tcgtctggta gaggaattta aggatatccc ggcagaagaa gtcaaagctg ctgtgcataa
     7501 gggctgggag gaaatggctg ctgcacgccg cgatgtacag aaaaaagggg aagaaaccct
     7561 gaaatatctg gaagatacag gacgccatgg tattgtcctt gcaggacgcc cataccatat
     7621 tgacccggaa atccatcatg gtatcccgga tctgatcaac agctatggta ttgccgtact
     7681 tactgaggat tccatctccc atctggcacc tgtggaacgc ccgatccgcg tcaatgacca
     7741 gtggatgtac cactccagac tgtatgctgc tgcaaactat gtaaagacac gcgatgacct
     7801 ggatctgatc cagctcaact cttttggatg tggtctggat gcagttacta cagacgaggt
     7861 ttatgaaatc cttgacggaa gtgacaaaat ctatacctgc ttaaagattg acgaggtaaa
     7921 taaccttggt gctgcaagaa tccgtatccg ttccctgatc gcagcgatcc gcgcgaagaa
     7981 agcacaggga cagaaacgta ctgtcaaacc tgcttctatt gataaagtat cctttacaaa
     8041 ggaaatgaga aaggactata ccatcctctg cccgcagatg tcaccgttcc atttcagcct
     8101 cctgcaggca gcattcaatt cctgcggata caacctggag gtgcttccga atgacaataa
     8161 gcatgcagtg gatgttggtc tgaagtatgt aaacaatgac gcctgctatc cgtctctgat
     8221 cgttgtggga cagatcatgg atgctctgct ttccggtaaa tatgacctga acaaaacggc
     8281 cgttgtcatg tcacagacag gtggcggatg tcgtgcttcc aactatatcg catttatacg
     8341 acgcgcatta aagaaagccg gtatggaaca gattccggtt atctctgtta acttaagcgg
     8401 tctggaaagc aatcccggat tcaaacttac gcttccatta gtgaagaaag ttgcttacgg
     8461 tgccgtattc ggagatatcc tgatgaaatg cgtatatcgt atgcgtcctt atgaactgga
     8521 agagggaatc gtaaacagga aacataaaat ctgggaacag cgtgtgatct ctttcttaag
     8581 cggaagcagt atcagccaca gccagtttaa gaaaatgtgc cgcgaaatgg ttcacgaatt
     8641 tgataccatt ccgatcagtg atgtgaagaa gcctcgtgtc ggcatcgtag gtgagatcct
     8701 tgtcaagttc ctgcctgctg caaataatca tctggcagag cttctggaat ctgaaggcgc
     8761 tgaggcagtt gtaccggatc tgatcgattt catgtgctac tgcttctata atcagaactt
     8821 taaggtagaa aatcttggat tcaagaagtc caaggcaacc atggcaaact ggggaatcaa
     8881 agcaatcgaa tgggtgagaa agcctgcaag cgaagctctt gcacagagcc gccattttgc
     8941 accgcctgct gatatcagag atctggcaaa aatggcatct ccgatcgttt ccaccggaaa
     9001 ccagacaggt gagggatggt tcctgacagg tgagatgatg gaactgatcc atggagatgt
     9061 tccgaatatt gtttgtatcc agcctttcgg atgtctgccg aaccacattg taggtaaggg
     9121 tgttatcaaa gaaatccgca gagaatatcc gacagccaat attgtagcca tcgactatga
     9181 cccgggtgca agtgaagtta accagctcaa ccgaatcaaa ctgatgctct ccacagctca
     9241 gaaaaacctg aaaaaagcag aagaaaaaaa tgcataaata ataccgtaat ggatatattg
     9301 caatgtattt taccttgcaa tatatccgcc ttagagcgtg tctgaaaaat aaaaattgca
     9361 caaaacgcat gttttatttc cctttt
//
