LOCUS       c00017_gnlPro..        16596 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GGOAGNBK_29.
ACCESSION   c00017_gnlPro..
VERSION     c00017_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:07:05
            Original ID  :: gnl|Prokka|GGOAGNBK_29
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 64341
            Orig. end    :: 80937
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16596
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[74341:79949]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15608
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..16596
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16596
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             1705..2235
                     /locus_tag="ctg17_60"
                     /transl_table=11
                     /translation="MNYNRLETSLIDVIKEEQAKLGYMKEKISLYYPLSSLNHFFGNET
                     DAAGMMEILKDFPSYIEEKFGEVAVSHRGDRFCFTVSEKASEYVHNNMKENEFIKALIE
                     LVGRHGCTIEEIKELFHSYSDKIITEPMDNEEFDVMIRFDDGSDPYYYCFKDEGCHIIY
                     HRFLPEDYADFGF"
     CDS             2488..3906
                     /locus_tag="ctg17_61"
                     /transl_table=11
                     /translation="MRKTKIICTMGPSTDKGDVMEQLVREGMDVARFNFSHGPHDEQRG
                     RIQKLRELRKKYDRPVAALLDTKGPEIRLGCFKDGKVSLEEGQIFTFTNKDIEGTNECV
                     SITYKELYKDVQPGGHILVDDGLVDLEVQDIAGKDIVCKVINAGVIGDRKGVNVPGANL
                     KMPFISKKDHDDLLFGIQEGFDFVAASFTRTANDIREVRKILKENGGEEIQIIAKIENQ
                     QGVDNIDEIIEAADGIMIARGDMGVEIPPEYVPVIQQKIIQKVYTAGKPVITATQMLDS
                     MISHPRPTRAEATDVANAIFQGTSATMLSGETAAGKYPVQALQMMSRIAEHMEQNIDYN
                     TIFKKTDRNENPDITNAIAHATCLTAIDLKASAILAVTKSGSTAHMMSKHRPGCLIGAC
                     TSSERVLRQLNLSWGVYPMLIKEEYSSEILCLRAIEAAQKHKLVKVGDTIVFAGGVPLG
                     IPGRTNLIRVCTVE"
     CDS             4075..4761
                     /locus_tag="ctg17_62"
                     /transl_table=11
                     /translation="MKTNEEEDSRHIFRGELALVIAVMINSLAVILMLYSGSGISAISS
                     VPYAFEKVFPVITLGTWTYIFQALLILSLMILRKKFVPAYLCSFLVGFAFSELLDVNEA
                     WINILPKTIPLRVLYFVISYLLICIGIALSNRCGLPIIPTDLFPRELSEIIKVKYSKIK
                     VSFDVICLMITACMTGLILGHINGLGIGTVMAAFTMGKVIGLIGDEMDKHFRFVNFTQH
                     CSLHVQ"
     CDS             4897..5094
                     /locus_tag="ctg17_63"
                     /transl_table=11
                     /translation="MQIMKRLLIKNKRKLWLWFLLLVFLFLACRAAYITGSKAEQTRNN
                     EVEERQADSRSIPNEMEILC"
     CDS             5088..5852
                     /locus_tag="ctg17_64"
                     /transl_table=11
                     /translation="MLNQFSRTELLLGKEAMNKLENSRVAVFGIGGVGGYVCEALVRSG
                     VGTFDLIDDDKVCLTNLNRQIIATRKTVGQYKTEVMRDRILDINPKADVRIHNCFYLPE
                     NAADFDFSEYDYVVDAVDTVTAKIELIMRAKEAGTPVISSMGAGNKLDASAFRVADIYK
                     TKVCPLAKVMRRELKKRGVKKLKVVYSEEQPIRPIEDMAISCRSHCICPPGATHKCTER
                     RDIPGSVAFVPSVVGLIIAGEVIKDLTAEYRR"
     CDS             6193..7377
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 78.3; E-value: 1.8e-24)"
                     /gene_kind="transport"
                     /locus_tag="ctg17_65"
                     /sec_met_domain="MFS_1 (E-value: 2.1e-24, bitscore: 78.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNYNRTVQACFIGYVVQAIVNNFVPLLFLTFQGSYGISLQKIT
                     LLVTFNFGIQLLVDLASIGFVDRIGYRASMILAHAMAAAGLILLTVLPECLGDPFVGLL
                     IAVMIYAIGGGLLEVLVSPVVEACPTDNKEKAMSLLHSFYCWGHVGVVLLSTLFFRIFG
                     IANWKYMALVWALIPIANGILFTRVPIAPLLDEGEKGLTMGELFKKKIFWVLMLMMLCA
                     GASEQAVSQWASTLAEKSFGINKTIGDLAGPMAFAILMGSSRAFYGKFGDKINLERFMQ
                     YSAVLCMVSYLMIAFIPVPALGILGCAVCGLSVGIMWPGTFSMAAASVKRGGTALFALL
                     ALAGDVGCSSGPTYVGMISGALNDNLKLGIFAALIFPVLMIMGIKMIGSLQKYD"
     CDS             complement(7790..8755)
                     /locus_tag="ctg17_66"
                     /transl_table=11
                     /translation="MSLLKEISITELSNLRIGHTSDHDAKTGVTVLYFPNGAKAGCDIS
                     GGGPASRETPLTSPVTADNPINAIVLSGGSAYGLAAADGVMNYLESQNIGYNTGAALVP
                     LVCQSCIYDLSYGNPKIRPTAKMGEEACRRAFAGTDTRTGNIGAGTGATVGKLYGMKQS
                     MKSGLGIAAVSVKNFQMAAIVVVNALGDIFSPQNGQKIAGLKTPDRSGFLDSVHELYRF
                     MTPHDQFTGNTTIGAVITNGAFSKAELNKIASMTRCAYARCINPVATMADGDSIYAASI
                     GDVSVDINMAGTLAAEVMAQAIQNAIHTSQIQDEEFLKYV"
     CDS             complement(9014..9652)
                     /locus_tag="ctg17_67"
                     /transl_table=11
                     /translation="MNTTTTTTTTAAAKRSSTLYMVELAMMIAIILLMSFTPLGYLRTP
                     GLSITLLTIPVAVGAIILGPKGGAVCGLAFGATSFYMAVTGSSAFAAALFNINPFGTFI
                     VCIVARVLEGWITGLIFAALYKSPAKKFSYYVASLACPLLNTFFFMGFLCLFFYNTDYI
                     QGIVSSLGVSNPVVFVAAFVGVQGLIEAGFCFVVGSIVSKALSVALKRA"
     CDS             complement(10001..10297)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_68"
                     /sec_met_domain="ALS_ss_C (E-value: 1.3e-21, bitscore:
                     68.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEVIKVIDFTDVFVRMKEILYIKVFNCSREDKAELFQIAETFQA
                     KVIDYGKDSLLLEFVQTATKNDAVVKLIKEEFHRIEVVHGGNVGIESISMMER"
     CDS             complement(10562..11275)
                     /locus_tag="ctg17_69"
                     /transl_table=11
                     /translation="MYLSDIHTHSIASGHGTTCTISDMAKAASKKGLKLLGISDHGPGT
                     LASGTSSYFRSLPFYPRKRFGIDILYGVELNILDSAGHTDLSDELLNNLDYAIISMHRQ
                     NYRSGSVSQNTEAYINAIKHPAVKILGHCDDTHFPVDYETLARAALRENVIFEINEASL
                     APGGYRGDTRANAARILYLCQKYQLPVILSSDSHGKEHVGDFTYAEEFVHQLMFPETLI
                     LNNQLPKLKVFLQTR"
     CDS             12038..13294
                     /locus_tag="ctg17_70"
                     /transl_table=11
                     /translation="VKSTERLIFHIDVNSAFLSWESARRVSQGLPDLREIPSCVGGNPK
                     KRTGIVVAKSIPAKKYGIQTGEPVAMALRKCPNLVIVPSDFELYDKCSRAFKAICASFA
                     PVMESFSIDEVFLDMTGTSLIYPDPVAAAHELKDKIHRELGFTVNVGISTNKLLAKMAS
                     DFQKPDRVHTLFPDEIPEKMWPLPIRNLLFLGKASEQKLLNQGIRTIGDLARERASNVQ
                     YWLGEKTGHQLWQYARGIDDSPVKAVPDEAKGFSVETTFNDDITSIEQVFPILLEQCDV
                     LATRMRRKDKKCNCISVTFRTLDFRNRSHQTKLENATDLTDEIYINATRLFKEFWKGQP
                     LRLIGVALTGLTDGTYEQMSLFEDTENKERRRKLDAAMDEIRMKFGNDKITRASIMNSN
                     TRIGRKAKAQMKNEKTEEP"
     CDS             complement(13363..13872)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_71"
                     /sec_met_domain="ALS_ss_C (E-value: 3.1e-22, bitscore:
                     70.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKGMKKRWISLYVENQVGVLSKISGLFSGKSYNLDSLTVGTTED
                     PTVSRMTIATVSDDETFEQIKKQLNRMIEVIKVIDFTDVFVRMKEILYIKVFNCSKEDK
                     VELFQIAETFKAKVIDYGKDSLLLEFVQTATKNDAVVKLIKEEFHRIEVVRGGSVGIES
                     ISMMER"
     CDS             complement(13890..15608)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_72"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.4e-48, bitscore:
                     155.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQISGNKLLVKALKEEGVEYLFGYPGACTIDISDELYKQDDVKI
                     ILPRHEQALVHEADAYARTTGKVGVCLVTSGPGATNLVTGLATANYDSVPLVCFTGQVA
                     RHLIGNDAFQEVDIVGITRSITKYGVTVRRREDLGRIIKEAFYIARTGRPGPVLIDLPK
                     DVMAELGSAEYPKNVNIRGYKPNTDVHIGQLKRAIKLLNKAKRPLFLAGGGVVISRAHE
                     IFREVVEKTKVPVVTTVMGKGSIPTDHPLYIGNLGMHGAYAANMAVSNCDVLFSIGTRF
                     NDRITGKLHEFAPHAQIIHIDIDTASISRNIQVDIPIVADAKEAITKMNEYVQECSTDK
                     WLNLIKNWKEEHPLKMRPNDLLSPMDILKEINEQFENSIIVTDVGQHQMLVSQYAEITE
                     GKQMIMSGGLGTMGYGLPGGIGAKIGNPDRPVIVISGDGGVQMNIQELATAVLEELPVI
                     LCIFNNEYLGMVRQWQKLFYGKRYAMTNLRAGALSRRTEGMEYPQYTPDFIRLAESYRA
                     KGIRVTKKEEIAAAFEEAKKNTKAPTVIEFIIDPEEMVYPMIKPGGTLEDMIMDC"
ORIGIN
        1 ttctgccatt gggaccgacc agctatggag attctccata tcagtctttc tctacatttg
       61 caggtaatcc atattttatt gatctggata cacttgtgga agaaggagtt cttgataaga
      121 aagactgcga gaaagttaat tggggaaaga agcctgatga ggtagattat gaaaaaatct
      181 acaaaggccg ttatcctctt ctgagaaaag catacgagaa cagtgatatc agcaagaatc
      241 ctgactatca gaaattcgta gcagagaaca gctggtggct gtcagattat gctctgttta
      301 tggcagtaaa agaccgtttc gaaggtgtag aatggaccaa atgggctgag gatatcagac
      361 tccgctggaa caatgccatg gattattatc gtgaagaact ctattttgat attgaattcc
      421 agcagtatat gcagtttaag ttctatgagc agtggatgaa actgaaatcc tatgcaaatt
      481 caaaaggaat ccagatcatt ggagatattc cgatttatgt tgcaatggac agtgctgatg
      541 catgggcgca tccggagctg ttccagctgg atcaggataa tgtaccgctg gcagtagcag
      601 gatgccctcc ggatggattt tctgcaaccg gtcagttatg gggaaatccg ctgtatcgct
      661 gggattatca cagaaataca ggatatcagt ggtggatttc cagaatgagt tactgcttca
      721 gactgtatga tgttgtgcga atcgatcatt tccgtggatt tgatgaatat ttctctattc
      781 catacggaga taaagatgca agaggcggac actgggaaaa aggtcccgga attgatctgt
      841 tccgtaagat cgaacaggcg cttggatgga agcaggttat cgcagaggac ttaggatata
      901 tgacagattc tgtacgtcat ctggtatatg agagcggctt cccgggaatg aaggttctgg
      961 aatttgcgtt tgactccaga gattccggat gtgccagtga ttatctgcca cataattatc
     1021 cggagaactg cgtggcatat acaggaaccc atgataatga aactatcgtg ggatggtgga
     1081 agagcatcac agcagctgag agaaaactgg cgagagatta tctgtgtgat catgcaacac
     1141 cggaagaaga actgtataaa tgtttcatca gtctgatcat gcgcagtgct gcgcgtgtct
     1201 gcgttatccc aatgcaggac tatatgggac tggacaacag attccgaatg aataaaccat
     1261 ctacagttgg tacgaactgg aagtggagaa tcaagaagag agatcttaca aagaaactcc
     1321 agaaggaaat atatgatgtg acacttcgtt acggacgtaa gaactgggat taaatacata
     1381 atgaaataat tggaataatg acagcgtttc ggatataaat aatattcgga acgctgtttt
     1441 tttaaccgaa tcaagcagtt atttggttaa aaaagcaacg aagtggttgg ttttatctgt
     1501 tttgttttat ccagtcagag ttatttgtca gagggagaaa aaaaggacag tttcgcaagc
     1561 tctttatttt tgtatgaaaa agaaaacatt gaaattgttt tggcgggcgt acaattgaaa
     1621 aagaaatgca ttgattttcg ggcaatgtct gataaaatat taaccagaaa aagcaaaagg
     1681 atagattttc aggagggaaa ataaatgaac tataacagat tagaaaccag tctgatcgat
     1741 gtgatcaaag aggaacaggc gaagcttgga tatatgaagg agaagatcag cctttattat
     1801 ccgctcagtt ccctgaatca tttctttggc aatgagacgg atgctgcagg catgatggag
     1861 attttaaaag attttccttc ttatatagaa gagaaatttg gtgaagtagc agtatcacac
     1921 agaggagatc gtttctgctt cactgtttcg gaaaaagctt ccgaatatgt acataataat
     1981 atgaaagaga atgaatttat caaggcattg atcgaactgg ttggcagaca tggatgtacg
     2041 atagaggaaa ttaaagaact gttccattct tattcagata aaatcattac tgaaccaatg
     2101 gataacgagg agtttgatgt gatgatccgc tttgatgacg gatcagatcc ttattattat
     2161 tgttttaaag atgaaggatg ccatatcatt taccacagat ttctgccgga agactatgca
     2221 gattttggat tctgataaga atgagtgaaa attttccaac tgtcggatca gtaaaaatat
     2281 atgtgatatt tgcaacaaaa gtatgttatt tttttgtcaa atatcaacaa aaataagtcg
     2341 aaattctata ttgacagata gtctcaataa tggtaatttt tatttgattt aatgttttca
     2401 tttatagaaa caggtaacat tttattacat tattttacag gaataaaata gataaaattg
     2461 agttgacagt ttggagggaa agattaaatg agaaaaacca aaattatctg tacaatggga
     2521 ccgtctactg ataagggcga tgttatggag cagcttgtga gagagggaat ggacgtagca
     2581 cgtttcaact tctcacatgg acctcacgat gagcagagag gccgtatcca gaaactgaga
     2641 gaacttcgca agaaatatga cagacctgtt gcagcacttc ttgatacaaa gggaccggag
     2701 atcagacttg gatgcttcaa ggatggcaag gtttctctgg aagaaggaca gatatttaca
     2761 tttacaaata aagatattga aggaactaat gagtgcgtaa gcattactta taaagagctt
     2821 tataaggatg tgcagccggg cggacatatt ctggttgatg atggacttgt agacctggag
     2881 gttcaggaca tcgcaggaaa ggacattgtc tgcaaggtta ttaatgcagg tgtgattggc
     2941 gacaggaagg gtgtcaatgt tccgggtgca aacctgaaga tgccattcat cagtaaaaaa
     3001 gaccatgatg atcttctctt cggtatccag gaaggatttg atttcgttgc agcatctttt
     3061 acacgtactg caaacgatat ccgcgaagta agaaaaatcc tgaaagaaaa cggtggtgaa
     3121 gagattcaga tcattgcaaa gattgagaac cagcagggcg ttgacaatat cgacgagatt
     3181 attgaagcag cagatggcat catgatcgcc agaggtgaca tgggtgttga gatcccgccg
     3241 gaatatgtac ctgttatcca gcagaaaatc atccagaaag tttacacagc aggaaaaccg
     3301 gttattacag caacacagat gcttgactcc atgatctctc atccgagacc aacccgtgca
     3361 gaggctacag acgttgccaa tgcgattttc cagggaacaa gtgcaactat gctttcagga
     3421 gaaaccgcag ctggtaaata tccggtacag gcacttcaga tgatgagccg tattgcagaa
     3481 catatggagc agaatattga ttacaataca atctttaaga aaacagacag aaatgagaat
     3541 ccggatatca caaatgcaat cgcacatgca acctgtctga ccgcaatcga cttgaaggcc
     3601 agtgcaatcc ttgcagtgac aaaatccgga agtacagctc atatgatgtc caaacacaga
     3661 ccaggatgtc tgatcggtgc atgtacaagc tctgagagag ttcttcgcca gctgaatcta
     3721 tcctggggtg tttacccgat gctgatcaaa gaagaataca gttctgagat cctttgcctg
     3781 agagcaatcg aggcagcaca gaagcataaa cttgtaaaag ttggtgacac tattgtattt
     3841 gccggtggtg taccgcttgg aattccggga agaacaaacc tgatccgcgt ctgcacggtt
     3901 gagtaagtca ggaaaatatc agtagttgaa gtgggaaact tgcctgattc gataaaaaat
     3961 agtattttca gaaaatataa gatgtaaaag acacaggggt ctgccgtcag aaaagtatga
     4021 cagaaaatat tttctgacag cagtcccttg cttgtgttag aggagagaat tgttatgaaa
     4081 acaaatgagg aagaagattc gagacatatt ttcagaggag agctggcatt ggtgatagca
     4141 gtcatgatca acagtcttgc tgttattctg atgctgtatt ctggttcagg aatatctgcc
     4201 atatccagtg ttccttatgc atttgaaaaa gtatttccgg taattacact gggaacatgg
     4261 acttatattt ttcaggcact tctgatctta agtctgatga tactgagaaa aaaatttgta
     4321 cctgcttatc tgtgcagttt tctggttgga tttgcattca gtgagctttt ggatgttaat
     4381 gaggcatgga tcaatatcct gccaaagaca attccactca gagtgttata ttttgtgatc
     4441 agttatctgc tgatctgtat agggatcgca ctttctaaca gatgcggtct gccgattatt
     4501 cctacagatc tgtttcctcg tgaactgtca gagattataa aggtgaaata ttctaagatc
     4561 aaggtttctt ttgatgtgat ctgtctgatg attactgcct gtatgacagg gctgatcctg
     4621 gggcatatca acggactggg aatcggaaca gtgatggcgg catttaccat gggaaaagta
     4681 attggattga ttggtgatga gatggataag cacttccggt ttgtgaattt cactcagcac
     4741 tgttcacttc atgtacagta acagagtttc ttcattgcag gatttttctt tctatgatat
     4801 acttgacgca ttatagaagt aaagatatca taagaaatct gtgatggaag tatgttgcaa
     4861 ctctggtatc tgaaaataat atattaagga atagtgatgc agattatgaa acggttgctc
     4921 ataaaaaaca aaagaaagct ctggctttgg tttctgctcc ttgttttttt gtttctggca
     4981 tgcagagctg cttacattac aggcagcaaa gcagaacaga ccagaaataa tgaagtagaa
     5041 gaaaggcagg cagatagtcg gtcaataccg aatgaaatgg agatattatg ttgaatcaat
     5101 tttcaagaac agagcttctt ctgggaaaag aagcaatgaa taaactggag aactcccgcg
     5161 tggcagtgtt tggaatcgga ggggttggag gatatgtatg tgaagcattg gtcagaagcg
     5221 gtgtggggac ctttgatctg atcgatgatg acaaagtatg cctgacgaat cttaacagac
     5281 agattattgc caccaggaaa actgttggtc aatataaaac agaggtgatg cgggacagga
     5341 tcctggacat taatccgaaa gcagatgtga gaatccataa ctgtttttat cttccggaga
     5401 atgctgctga tttcgatttt agtgagtatg attatgtggt agatgctgtg gacacagtga
     5461 ctgcgaagat tgaactgatc atgcgtgcaa aggaggcagg gactcctgtt atcagcagta
     5521 tgggtgccgg aaataagctg gatgccagtg cgtttcgggt ggcggatatc tataagacga
     5581 aggtgtgtcc gctggcgaag gttatgcgta gagagctgaa gaagcgtggt gtgaagaaac
     5641 tgaaggttgt ttattcagag gaacagccga tcagaccaat tgaagatatg gcgatcagct
     5701 gcaggtcgca ttgtatttgt cctccaggtg ctacgcataa gtgtacggag cgcagagata
     5761 ttccggggag tgtggccttt gtgccgtctg tcgtcgggct gattattgca ggagaggtta
     5821 ttaaagacct gactgcggag tacagaagat aagaagtgtt tattttgaga tgtgtatggt
     5881 gtcagaaatg gtatggtaca catctttttt tgcgggaaat attttgaatt ggattgatgg
     5941 attacctgtt agagtgtata gaattgttat atgagaaaaa gtcaaaataa cataaaaatt
     6001 tataggattt tcaaaatata atgaaagaaa aaagaaagaa tctgtgatac actgtcatta
     6061 ttgattgata gaactgtgaa ggtgcagaat ttggtgaatg agaatgcctg aacgatatca
     6121 gcgtaataaa ttgttactgc ttactccgtt ctcagtaact aataaatttc agattggagg
     6181 atatcatatc gaatgaaaac aaattacaac agaacagtgc aggcctgttt tatcggatat
     6241 gtagtgcagg ccattgtgaa caatttcgtt cctctgctgt ttctgacatt tcagggcagt
     6301 tatgggattt cgctgcagaa gatcacactt ctggttacat ttaatttcgg gatccagttg
     6361 ctggtagatc tggcatcgat tggatttgtg gacagaatag gttatcgtgc atctatgatc
     6421 ctggcacatg caatggcggc tgcaggtctg attttgctca cagtattgcc ggagtgcctg
     6481 ggagatccgt ttgtgggact tctcattgca gttatgatct atgccatcgg aggcggattg
     6541 ctagaggtgc tggtaagtcc tgtggtggaa gcctgcccta cagataataa ggaaaaagca
     6601 atgagtctcc ttcattcctt ttactgctgg ggacatgtgg gagtggtact tctttctaca
     6661 ttattctttc gtattttcgg gattgcaaac tggaaatata tggcgctggt gtgggctttg
     6721 attcccattg caaatggaat cctttttacc agagttccca ttgctccgct gctggatgag
     6781 ggtgaaaagg ggctgactat gggagagctt tttaagaaaa aaatcttctg ggttctgatg
     6841 ttaatgatgc tctgtgcagg agccagtgag caggcggtaa gccagtgggc ttctactctg
     6901 gctgagaaaa gctttggaat caataaaact atcggagatc tggcaggtcc catggcgttt
     6961 gcaattctta tgggaagctc aagggcattt tatgggaaat ttggagataa aatcaatctg
     7021 gaacgcttta tgcaatacag tgcagttctg tgcatggttt cctatctgat gatcgcattt
     7081 atcccggtac ctgcgttggg aatccttgga tgtgcggttt gcggtctgtc tgtaggtatt
     7141 atgtggccag gaaccttcag catggcggct gcctcagtaa agcgtggcgg aacagccctg
     7201 tttgccctcc ttgcccttgc tggagatgtg ggatgctcat ccggaccaac ctatgtgggg
     7261 atgatttcag gagcactgaa tgataatctg aaacttggaa tctttgcggc attgattttc
     7321 cctgtgttga tgataatggg gattaagatg attggaagtc tgcaaaaata tgattgagat
     7381 atattaaaaa gtatggaacg attaattttt catattgatg taaacagcgc atttctttcc
     7441 tgggagtcag ccagaagggt aagccagggg ctgccggatc tcagggatat tccctcctgt
     7501 gtgggaggaa atccaaagaa acggacagag tacacacgct gttcccggac gaaataccgg
     7561 agaaaatgtg gccacttcct gtccgtaaca tgttatttct gggaaaagcc tccgagcaga
     7621 agcttctgaa tcagggaatc cgtactattg gtgatctggc aagggaacgg gaagcaaatg
     7681 tacagctctg gcttggagaa aaaccagagc acagatgaaa aatgaagaca gacaggaaga
     7741 ataaaagcgc agagatgata ctttttctct gcgcttttat agcggactgt tatacatatt
     7801 tcagaaattc ttcatcctgg atctgggaag tatggatggc attttggata gcctgagcca
     7861 tgacttctgc ggcgagagtt cctgccatat tgatatctac agaaacatcg ccaatgctgg
     7921 cagcatagat ggaatcgccg tcagccatag ttgctacagg attgatgcat ctggcatagg
     7981 cacagcgggt catagaggca attttattca gttcagcctt tgaaaatgcc ccattggtga
     8041 tcacagctcc gatggtggta ttgccggtaa actggtcatg aggtgtcata aagcggtata
     8101 attcgtggac actgtccaga aacccgcttc tgtcaggcgt tttcagccct gcaattttct
     8161 gaccattttg tggactaaag atatctccca gtgcattgac aacgacaatt gcagccatct
     8221 ggaaattttt cacagataca gcggcaatac caagacctga cttcatggac tgtttcatac
     8281 cgtaaagttt tcccacagtt gcaccggtac ctgcaccgat atttccggtt ctggtatctg
     8341 ttcctgcaaa tgcccgacgg caggcttctt cgcccatttt tgcagttgga cgtattttag
     8401 gatttccgta agagaggtca tagatacagg actggcatac aagaggaacc agggctgcac
     8461 cggtgttata accgatattt tgtgattcaa gatagttcat tacaccgtca gcagcagcca
     8521 gtccataggc agaacctccg gacaagacaa tagcattgat gggattgtcg gcagtgacag
     8581 gagaggtgag aggagtttct ctggaagcag ggccgcctcc gcttatatcg cagcctgctt
     8641 ttgctccatt tggaaaataa agaacagtta caccggtctt cgcatcatgg tcagaagtat
     8701 gaccgatgcg taaatttgaa agctctgtaa tagaaatctc ttttaataat gacataaaaa
     8761 tctcctttat tatgtgatag caattctatg aaatactgag agcaatccag cctatcagaa
     8821 tgtgaagtac tgcgtcagat attttccttg tctttcgcac tctgctgaac tgtcttgatt
     8881 gcattatttt gtgagattgc tatagatatt aattgaatca ggtaggattc ctgttttaaa
     8941 tgtgccagat aaaaaaacct gactacggtg acaatgtagt caggtttttt ggaaaaggct
     9001 gttcttttaa agattatgca cgtttcagtg ccacagaaag tgccttggaa acgatacttc
     9061 ccactacaaa gcagaagccc gcttcgatca gtccctgaac gcccacaaaa gcagcaacga
     9121 agacaacagg attgcttact ccaagactgg aaacaatacc ctgaatgtaa tctgtgttgt
     9181 agaagaagag acataaaaag cccatgaaga agaaagtatt cagtaacggg catgccagtg
     9241 aagcaacgta ataggaaaat ttcttcgccg gtgatttata taatgctgcg aaaataagtc
     9301 ctgtgatcca tccttccagc acacgtgcca cgatacatac aataaaagtg ccaaatggat
     9361 taatgttaaa aagtgcggca gcgaaagctg aacttcctgt gacagccata tagaagctgg
     9421 ttgcaccgaa agcaagtccg catacagcac cacctttcgg tccgaggatg atagctccta
     9481 cagctaccgg gatggtgaga agagtgatgg ataagccggg agtacgaagg tagcccagcg
     9541 gggtaaagga catgagcaga ataatggcga tcatcatagc caactctacc atgtaaagag
     9601 tgctgcttct ttttgctgca gccgttgttg tagtggttgt tgttgtgttc atatgaattc
     9661 tccttttggt ctgataaaac ggcgcaatgc gtcccctgct tttcagacag tttagagtat
     9721 ggggatcagg cgttatgaaa aatatgcatc agaacaaaag aaaaatttcc ggtgtgtaga
     9781 cgccttacag gtcgcctcac gaatttaacc agactgtgaa gtggatgact ttatccacca
     9841 gactgtcaga tgtggaaaac agatgcattt tctttcgaat aacgctcccg taaaccataa
     9901 cacatttgat taaaaactgc aatattttat agtatgtttg aaaataaata caggatatag
     9961 aggtgtttct atatcctgta aaaaatattg attatgagat ttagcgttcc atcatgctga
    10021 tggattcaat tcctacgttt ccaccatgta ccacttcaat tctgtggaat tcttccttga
    10081 tcagtttgac aactgcatca ttcttggtgg ctgtctggac aaattccaga agcaggctgt
    10141 ctttgccgta gtcaatgact tttgcctgga aggtttctgc aatctgaaac agttctgctt
    10201 tatcttccct ggagcagttg aaaaccttga tgtagagaat ttctttcatt ctgacaaata
    10261 catctgtgaa gtcgattacc ttgataacct cgatcatgcg gtttaactat tttttgatct
    10321 gttcaaaggt ttcatcatcg ctgactgttg cgatagtcat tcgggatact gtaggatcct
    10381 cggtggttcc tacagtaaga ctgatctatc acgagatatg taaatggtta agtgagtttt
    10441 gttaattaaa atgtactaaa atgtcgtctt ttttgacaag aaattataga aaataaacaa
    10501 aataacacaa tgcaaaaaac aatgcataaa ataaaagaat gtccctttga ggaacattct
    10561 tttaacgtgt ctgaaggaaa acttttaatt tgggaagctg gttgttaagg ataagagttt
    10621 ccggaaacat gagctggtga acgaattctt cggcataggt gaaatctcca acatgttctt
    10681 ttccgtggct gtcgctggac aaaataacag gaagctgata tttctgacag agatacagga
    10741 ttctggctgc attggctctt gtgtctcccc gatatcctcc gggtgcgagg gaagcttcgt
    10801 ttatttcaaa aataacattt tcccgtaaag ctgctcttgc cagcgtttca taatctacag
    10861 ggaaatgtgt atcgtcgcag tggccgagta tttttacagc aggatgtttt attgcattga
    10921 tgtaagcttc tgtattctga gatacagagc ctgaacggta gttctgccga tgcatactga
    10981 tgatagcgta atccaggttg ttcagcagtt catctgacag atctgtatgt cctgcactgt
    11041 ccaggatgtt tagttcaact ccgtaaagaa tatctatgcc gaatcttttt ctgggataaa
    11101 aaggaaggct tctgaaataa gaagaagttc cggaagccag agttcccggg ccgtggtcag
    11161 aaatcccaag gagtttcagt ccttttttgc tggctgcttt tgccatgtca gagatggtac
    11221 aggtggttcc gtgaccgctg gcgatagaat gtgtgtggat gtcagaaaga tacattgttt
    11281 gtctcctttc cagagcggtt tctatatatg ataagagcct tacggaagat gcaaagctgc
    11341 tgtttgatgg tacattcgtt atattcaagt atgacagatg aggatttaaa tgtcaatgag
    11401 gaaacaaaat aaaaacaact gaaatacaac aaaaatcaaa taaaaagcaa cacaaataaa
    11461 cggctgatac atgttaaatt atgttgactt cgggaaaatg agaaggtata atggaactat
    11521 atgaaaacat gggggcttat tgctgatcaa tgacagcgat ggcactgttt gcttatgtgt
    11581 agacagttac ttcatgagaa aggagtaaca tggaaaaatt tcaaacatca gacattcccg
    11641 gaattctctt atgaatggct ggaggctgaa ctggatactg gtatgattcc acaaatatgg
    11701 acagcgaaga aattgctcct aacctttatg actaatcgat aagtatatat cgagaggaaa
    11761 tgaatcctca gaattaagta aaaaaagtta ccgggaacaa tgtgaccggt agcgaaatac
    11821 agacgccgca ctgccgtatg gcaagtgcgg cgttgttgtt caaaactctg atagcagagt
    11881 gaaatcaaac aaatataaat acagtaacag ctcagacaag atgatgcaaa taaagacact
    11941 tttttggaca aacgaggttc ttaccctgga gagcagatca gggtaaaatg aaatcatcag
    12001 atatgaagag cgcaattcat atattggagg aagaacagtg aaaagtacgg aacggttaat
    12061 ttttcatatt gatgtaaaca gtgcatttct ttcctgggaa tcagccagaa gggtgagcca
    12121 ggggttgccg gatctcagag aaattccttc ctgtgtagga ggaaatccaa agaaacggac
    12181 aggtatcgtg gttgccaaat ctatccctgc aaaaaaatac gggatccaga ccggcgagcc
    12241 agtagctatg gctcttcgga aatgtcccaa tttggtgatc gttcccagtg attttgaatt
    12301 atacgataaa tgttcccggg catttaaagc aatctgtgct tcctttgcac ctgtgatgga
    12361 atctttttcc attgatgagg tatttctgga tatgacaggt acttctctga tctatcctga
    12421 ccctgtagct gctgctcatg agctgaaaga caagattcac agagagctgg gattcacagt
    12481 aaatgtggga atttctacca ataagctttt ggcaaagatg gcatcagatt ttcagaagcc
    12541 ggacagagta cacactttgt tcccggatga aattccagag aaaatgtggc ctcttcctat
    12601 ccgtaatctg ctgtttctgg gaaaagcttc cgagcagaag cttctgaatc aggggatccg
    12661 taccatcggt gatctggcaa gagaaagagc atccaatgtg cagtactggc ttggggaaaa
    12721 aacgggacat cagctatggc aatatgccag aggtattgat gattcccctg taaaagcagt
    12781 gcctgatgag gcaaaaggtt tcagtgtgga aactactttt aacgatgata ttacttccat
    12841 agagcaggtg tttcccatac ttttggagca gtgtgatgtt ctggcaacca gaatgcgcag
    12901 aaaagataag aaatgcaact gtatttccgt gacttttcgt actttggatt tcagaaaccg
    12961 ttcacaccag acaaagctgg aaaatgctac agatcttaca gatgaaattt atataaatgc
    13021 tacaagactt tttaaagaat tctggaaagg acagccgcta cgtctgattg gtgtggcact
    13081 gacaggcctt acagatggca cttatgaaca gatgtctctg tttgaagata cggaaaataa
    13141 agaacgccgc agaaagctgg atgcagctat ggatgagatc cggatgaaat ttggaaatga
    13201 taagatcacc cgtgccagta ttatgaacag caatacacgg attgggcgaa aagcgaaagc
    13261 acagatgaaa aacgaaaaga cagaagaacc gtaagtaaag ggaggactga gcattaagaa
    13321 taatgcgaca atcctccctt tataaaaatt tcagaaaaag ttttatcgtt ccatcatact
    13381 gatagattcg attcctacac ttcctccacg taccacttca attctgtgaa attcttcctt
    13441 gatcagtttc actactgcgt cattcttggt tgctgtctgg acaaattcca ggagcaggct
    13501 gtctttgcca tagtcaatga cctttgcctt gaaggtttcg gcaatctgaa acagttcaac
    13561 cttatcttct ttggaacagt taaaaacctt aatatacaga atctctttca tgcggacaaa
    13621 tacgtctgtg aaatcaataa ccttaataac ctcgatcata cggttcaact gttttttgat
    13681 ctgctcaaaa gtttcatcat cactgactgt tgcgatagtc attcgagata ctgtggggtc
    13741 ctcggtagtt cctacagtaa gactgtccag attgtagctt tttccggaga aaagtccgga
    13801 gattttggac agaacaccta cctggttctc aacatagaga gaaatccatc tttttttcat
    13861 tcctttatcc ataataattt tcctcctgat caacagtcca taatcatatc ttccagagtt
    13921 ccgcctggtt tgatcatagg ataaaccatt tcctcagggt caatgatgaa ttcaattact
    13981 gtaggtgcct ttgtgttctt ttttgcttcc tcgaaggctg ctgcaatttc ctctttcttt
    14041 gtgacacgga ttccttttgc cctgtagctc tctgcaagtc tgatgaaatc cggtgtgtac
    14101 tgtggatatt ccatgccttc agtgcggcgg gaaagtgctc ctgcgcgcag attggtcata
    14161 gcatagcgtt tgccgtagaa aagcttctgc cactggcgta ccattccaag gtattcattg
    14221 ttaaagatgc acaggataac aggaagttct tccagaactg cagttgcaag ctcctgaatg
    14281 ttcatctgca caccgccgtc accggagata acgatgacag gtctgtcggg atttccgatt
    14341 ttggctccga tgccgcctgg aagaccatag cccattgttc ccagaccacc ggacatgatc
    14401 atctgtttgc cctctgtgat ttccgcatac tgggagacaa gcatctgatg ctgtcctaca
    14461 tctgttacga taatactgtt ctcaaactgt tcgttgatct ctttcaggat atccatcgga
    14521 cttaaaagat catttggacg cattttaagc ggatgctctt ctttccagtt tttgatcagg
    14581 ttaagccact tgtccgttga acattcctgg acgtattcgt tcattttggt gatagcctct
    14641 tttgcatcag caacaatggg gatatccacc tgaatgtttc gggaaatgga tgctgtatca
    14701 atatcaatgt ggataatctg ggcatgtggt gcaaattcat gaagttttcc ggtgattctg
    14761 tcattgaatc tggttccgat ggagaacagc acatcgcagt tgctgactgc catatttgct
    14821 gcataggcac catgcatgcc aaggtttccg atatagagcg gatggtctgt ggggatagag
    14881 ccttttccca ttacggttgt gacaaccggt acttttgtct tttccactac ttcccggaaa
    14941 atttcatggg cgcgggagat tactacaccg ccgcctgcca ggaataaggg acgttttgct
    15001 ttatttaaaa gtttgatggc acgtttgagc tggccgatgt ggacatctgt gtttggtttg
    15061 taaccgcgga tgttgacatt tttaggatat tctgcgctgc caagttctgc catgacgtcc
    15121 tttggaaggt cgatgaggac aggtcccgga cggccggtgc gggcaatgta gaaggcttcc
    15181 ttgatgatac gtcccaagtc ttcacgtctg cggacagtaa cgccgtattt ggtgatgctt
    15241 ctggtgattc ctacgatgtc tacttcctga aatgcatcgt tgccgatgag gtggcgggct
    15301 acctggccgg tgaagcatac aagaggtacg ctgtcatagt tggcggttgc aagtcctgtt
    15361 acaaggttgg ttgctccggg accgctggtt accagacata cgccgacttt gccggtggtt
    15421 ctggcgtagg cgtcggcttc gtgtacaagg gcttgttcgt gacgggggag gatgattttg
    15481 acgtcgtcct gtttatagag ttcgtcactg atgtcgatgg tacaggctcc ggggtagccg
    15541 aagaggtatt ctacgccttc ttcttttaag gctttgacta agagtttgtt gccggatatt
    15601 tgtttcatat tttggtaaac ctcctttgtg tatgtgtata ggacgctcag aaatttattt
    15661 gtttggtgtg cggtttcgga gcctagtaga tctaagtgtc tgaaaatctg ctaaaagcgt
    15721 tcagaaaaat ctcaaactcg ctgcgctcag acagtgagat ttttctgaac aacgcagatt
    15781 tctaggcact aagatctaca cgactcctgc aaatgcacac caaacaaata aatttctgag
    15841 ctgtgtattg gctgatacag gggcagaatg gcgctgcgct gattctgctg agaacgctgt
    15901 aaagcagctc ccacaattct gaatatagta aaaaacgccc tgggcttgtt tgcccagggc
    15961 gaaaatgttt ccgcggtacc acctgtattc agagtctggc tctgcacttt gtcagtactg
    16021 atatactgtg ttcctgtaac gtggaactga cgttgaagcc tacttggcat gtctgtccgg
    16081 gtctatgaat catctgactg gatatgcggt ttggttcact gctcgggggc tacttccaca
    16141 attcgttcac aaaagctcgc accgaccgct ttctctctgt gcttcccggg gttgtgtact
    16201 cctccctgtc atggcatttg gctgatatag ggatattcat tgtccgaata gggtggacaa
    16261 atgttttctt gggttacatt atacatttat agagaggaaa ttgtcaaccg ggttttggat
    16321 aattgctgta aaatttatgt tcctgaatga attttggcta cgttactgag aacggagtga
    16381 acagtaatgt aattgacaga tttctatatt gctgatataa aaaataaata atacagctgt
    16441 ttggaaggtt attaacagtt aaatataaat tataaaatca tataagcaca tgttgagttt
    16501 tgcaagatat tagagtagaa tattattgaa aggagttgat tctttgagta aatattattc
    16561 tatacatgaa ttttcaaaaa ttataggcgt atctgc
//
