LOCUS       gnlProkkaFKHCHIMF_145  13704 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FKHCHIMF_145.
ACCESSION   gnlProkkaFKHCHIMF_145
VERSION     gnlProkkaFKHCHIMF_145
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:28:01
            Original ID  :: gnl|Prokka|FKHCHIMF_145
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13704
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13704
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1353:4047]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1354..4047
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..13704
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13704
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             complement(246..476)
                     /locus_tag="ctg100_1"
                     /transl_table=11
                     /translation="METTVMNVAVSQGIWAVLAVFLLIYIVKSNEQRDTKQEEREKNYQ
                     TVIESLTEKFQILNQVQSDLKEIKDNLFNKN"
     CDS             777..1301
                     /locus_tag="ctg100_2"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYNVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILRYISENK"
     CDS             complement(1354..4047)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     763.1; E-value: 7.2e-231)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_3"
                     /sec_met_domain="DUF4135 (E-value: 6.7e-94, bitscore:
                     304.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.4e-52, bitscore:
                     168.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLKLDYLCRKNRTMFLKILILDVHRQKNFGNLKGSTPKEQYDYY
                     EKKYLNNATYVKSLLQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRK
                     FSGTVGIYMSKGDIHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGIS
                     CRTVQYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAH
                     GEYPVIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNR
                     GVLISAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYT
                     ECIIRGFCRAYMVAMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRE
                     CRKALLNVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLP
                     CTPYESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIY
                     SQIRKIVHRICSRAIIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLH
                     DFEEKNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLT
                     GKRVWMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADME
                     KDLWKKGQETGNGYGWRLKGTDGPLAGMSHGNSGFLMAYAALYECNHKAEYADKIQLLL
                     RYEDSLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLN
                     AADSLFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAK
                     ISGTEYLNLAFMNGISGTGMALMEIL"
     CDS             complement(4038..4166)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg100_4"
                     /transl_table=11
                     /translation="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYGTIVCC"
     CDS_motif       complement(4056..4166)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /locus_tag="ctg100_4_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4038..4055)
                     /prepeptide="core"
                     /locus_tag="ctg100_4_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="519.7"
                     /monoisotopic_mass="519.2"
                     /core_sequence="TIVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /leader_location="[4055:4166](-)"
     CDS             complement(4183..5664)
                     /locus_tag="ctg100_5"
                     /transl_table=11
                     /translation="MLKVLLYGLATFMETGIGVWIFSQTFSERRILEKKYYVLEWLLYS
                     LIFFGIYNFSVSLWQIDKKIEKYVIKVICIYIIGLIAGIIYDIFFVKKKEMVLRRILYI
                     GMIFWLTAQYWAGYQSLLMIILGSGIIVLYVFCYFDCTFKQAYVWNFFYAVNIGLIKEA
                     YVVYAGVFNHKQWDDFYSYPRGHTYQEVIFWILGCLFIFWIIKFILSVNSIKGILRTRL
                     KELFIIGLLEYVLLIVSIIYKFGTIKKENFVMTACLLAVSNIALIGVYVKFQKKTLEMR
                     NQILDMRCKLMEEEYEELRMSYDRYRCLVHDEKHLLLYIKECLENGELDSCITFLNHYK
                     RESIRYSGVAWTGIPEINFMLNIKVRKMEEKNIFFKVDSKIEKIPMKDIDFVVLLGNLL
                     DNAIEAAEKCEEGKGKITCIFRNINDMFIFKVKNTSIYKPYEKNTKFYTSKKEKDEHGW
                     GIESVKQIVRKYNGEIDFKYDKDFFEVEIIISDNT"
     CDS             complement(5668..6375)
                     /locus_tag="ctg100_6"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKDITEQYFAEKNVDCTVTIYQKVEWFLL
                     GLNEEKFDMYILDIRMPGENGIEAAREIRRLYPDPVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKEKLPQAYDALLPGIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTVEKELNSKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGV"
     CDS             complement(6381..6935)
                     /locus_tag="ctg100_7"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTIREILKKTGKTREDFFPKGYLLGKRIKLTKSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKGDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             7054..7389
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.6; E-value: 4e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg100_8"
                     /transl_table=11
                     /translation="MKNNTIGKRIAEARINRNITQEHLEELSGLSVSTISRIETGKYMP
                     TIENLLKLSEILDVGLDYFLYDLLPHNKDIQSPAIQDAISIMNQMGERQTEYIVKILKI
                     YQASHQD"
     CDS             7577..8470
                     /locus_tag="ctg100_9"
                     /transl_table=11
                     /translation="MTKTEKAVTWAIRIANDPAHGYDQDNRWGPDYDCSSLVISAWQQA
                     GVPVKTKGATYTGNMKSVFLSCGFKDVTSKVNLSTGSGMKRGDVLLNIASHTVMHIGNG
                     QVVSASKNENNGYHGGKPGDQSGKEIKLQSYYNFPWDCVLRYTEDSSTTDPDPEPQPTA
                     GNAKIRKGQGYANKFANAGISITGKRDAATKKAGVKVLQTALNRDYGAGLDVDGIWGTN
                     TDNALGQHYVKNGETQYMVTAAEILLLLRAYDPNGVEIPGTFGSGLLSAVKAFQKAQGL
                     TVSGTCDRNTFLKLIS"
     CDS             complement(8616..9374)
                     /locus_tag="ctg100_10"
                     /transl_table=11
                     /translation="MKQKKIAIIMAGILAAAAAMTGCAEQNKTETQVDYTQNSQEKSEQ
                     TKQKTAEKSQPDKKQVNKSTSIGKEDSNQTADKKTKISASSNNAGDVQNSENGTDSTAG
                     TDTDDSQTTGVDTSASEDNGSTGNGGTQSDQRADQAMIYDSEGNGRLISEADDGNWYDS
                     DGNYYGSWEDIEDAMVNENGVTDQDGNKYYWTAPHDASEEVTDPYDLYSWDPGTNSYIP
                     FQAAESDCSPVGRGNGWYYYDEDSGEYVPW"
     CDS             complement(9614..12295)
                     /locus_tag="ctg100_11"
                     /transl_table=11
                     /translation="MKSNYKIFTAVFLSAIMTAAAPLTVCGAEVFSAGESFSDGTGSIP
                     AILTDMVLPDGEIGTEYQVQLEADTDVNWSLEEGSELPAGFTLSSGGVISGMPQEEGSF
                     SFTVQADNGIGVSSQELSLYVAQREQEPVIKQYELTSGTALIDLGIHAEGEQSRKRLFL
                     YNAGTDSLHLSDFPQSRYFDFSYAPIFDTNTDEEMQPGSCAAVDIDDKKNLPAGNYEET
                     VTFETKEGASCKVTLKVIVGASSEKDYELSIETGTEEEFTESDFYDPEFRVEKYVVVRN
                     SGKKETRIRIDTSGLKNFEVDDQMAKWTEDYEEQDSKKLLKPGETLYFYILPKQEYGIY
                     DETFAFLADDGSRYPLHVTMNREKNPTEKKQLEITEKSAGGFPTMQWGYKTLPEAKTYI
                     LKNVTDTDMKLSFNRSKECSVLLSGNAYLAPGESTELRLWPKLGLSVGKYSFQVTVTAK
                     TVAGEHLTTQNLYNSFIVGDRTYQGLADAVAPVTGITNGAEKTADALHLPKSLEVYGAE
                     VNGEKTTFSASVKWDVENCAYDPKSKAAQSFLVNGSLELNEDENNEGLDTAVQIMVQVD
                     AYQTLNRPVIDTRWTRVITNYAMLYLRDLSNEADGYQFVTAKSQKDLKKGNYTAQTKIT
                     NSELNQYPELKYIPEGTHSLYCRAYKENSSHVMEYGEWSDGVPVTVKAKTPDAPVVQKV
                     QVKKNDVRIVLNSKGEEPDGYDVVAARSKNGKEPSDYIKVKSGYSGSSKELILRGVPAG
                     TWYIGVHAYKYLNGSNTKVLSKWAEVRKVTVKTSLVTGKPAVKSAKVSRQGTKRNVAVT
                     FTVPKSCDGTDWVLAKKVSKSDNGSYTGVSSYAYTKKNQTKTTVVFKNVKPGVYYLAGR
                     AYVKGYAKSYTKWSKIKKIVVK"
     CDS             complement(12490..13458)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 214.8; E-value: 3.4e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg100_12"
                     /transl_table=11
                     /translation="MKLGILGAGGIASTMAKTVAGMKDVEAYAVAARDLERARVFAQKY
                     EVKKAYGSYEEMLADDEVGLVYIATPHSHHYLHAKMCLEAGKHVLCEKAFTVNAEQAQK
                     LFDLAKEKKLLITEAIWTRYMPSRKMINDIIESGVIGEVTAVTANLSYTVSHVERIRKP
                     ELAGGALLDVGVYPINFASMVLGDKVKDVKATAIFQNGVDILDSIAMVFEGDRMATLQC
                     GAREISDRMGSIFGTRGYMQVQNINNPEKITVFDTEHKEVASYVVPEQISGYEYEVESC
                     MKAIHEGKTECPEMPHAETIRIMKIMDDIRKSWNYEIPCIE"
ORIGIN
        1 aaggtactat ataggagatc aaatagtttt tacaaactct tttgacccca acatctttac
       61 tatacgaaca tctgtaaatc tgggattaaa agtattctaa tggacacgaa tgttatgctt
      121 atattcatct accattttag taaacatatt tttctcaaat taacctattt tcttacctaa
      181 aatgacagaa gccctctccg ctggaaaaat atatcctgca gaaaaggctt ttttcttttc
      241 cctatttaat ttttgttaaa aagattatcc ttaatctctt tcagatcgct ttgaacctga
      301 ttcagaatct gaaatttctc agttaaactc tcaatcaccg tctggtaatt tttctctcgt
      361 tcttcctgct ttgtatccct ctgttcattt gatttcacaa tgtaaatcag aagaaaaacc
      421 gcaagcacag cccagattcc ctgtgaaact gccacattca taaccgttgt ttccatggtt
      481 tctgcctcct tccttaatct tcttttatta tgcaaacttt ttctatgttt tgtctactaa
      541 aagtcttttc taatcttatt attaccgttt taatttaaag catatttcta ttctctacaa
      601 ttattttgca aatctctttt taccatgtat ttcttctcct atcgctgatc taaatttgca
      661 acctcactta ataaagagtt ttttctcttc catttgtaaa ctcacaaatt tttttctttt
      721 ttagtttctg atcagcagtt ttcttactac ttcccctaaa aaggaggtag atacctatga
      781 aaacactgac agaacttatc caaaattatc aaaatggtat cccagattca gacagtgaaa
      841 ttctcaaacg tatggaaccg cttgtgaaag gatatgcatc ccggattcac tgcatggaac
      901 gcgaagattc cacacaggaa ttgtatctta ctttgttaaa gacattgcca tatttaagtt
      961 cttcatcctc agaaggtgaa tgtatcagat acatgcagac ctctgtcgaa aacagatatc
     1021 gttccctttg ccgcagttgt ctttccgaac ctgaaaaaga tgattttgat tcttgttctg
     1081 tttcattaca ggctcccgac agttttgatg acacctatta taatgtaacc gcatatatca
     1141 actcttaccc ttcggacagt gtccagagaa aaattctgtc catgtacttt tatcaggata
     1201 aaagcgatgc ccagattgcc cggaaactga agctgtcccg ccagtacgtc aatcggatga
     1261 agaagaaact aattctcaga tatatttccg aaaacaaata aaagaaacac ctgctgacca
     1321 taaatttaca gtctgcaggt gttcccttag ttttcataaa atttccatta atgccattcc
     1381 cgtaccggaa atgccattca taaaagccag attcagatat tctgtcccag atatttttgc
     1441 cgggtgatcc agttgaaata aaaggcagtc acataacgcc tcatattgct ccttcatttt
     1501 tttattacca tattttcgaa ggtacttctt cataataagt aaattcccgg acatcccatg
     1561 acacagacaa attttttcat cctgttctcc ataaaacaaa gagtctgcag catttaacct
     1621 gtctttttta atctgcatat cctcaggaaa cagctcttcc agtttcattc gtgaaagcag
     1681 gattcccggc gccccatggc accatgcatt catgaagctt tcccctgaac tctctcgtaa
     1741 atccttccag tttccggctt tctctgagta cagagaatcc tcatatctca gcaaaagctg
     1801 tattttatca gcatattccg ctttatgatt acattcatac aacgctgcat aagccatcag
     1861 aaatccactg ttgccatgag acattccagc cagcggtccg tctgttcctt ttaatctcca
     1921 tccgtatcca tttccggttt cctgtccttt cttccacaaa tctttttcca tatctgccgc
     1981 tatttcataa tatttcagat ttccggtttc tttatataac atcactgcca ctacaatagc
     2041 tccggcattt ccgctcagat aatccagttg tgaatcttct ttccataccc tctcaataat
     2101 gctgaaatgc ttttccgcat aaatcatcca cactcttttt cctgtaagtt taaacagata
     2161 aagataggta tataccaccg agctttctcc atttacaata cctgtcagaa gatttttatc
     2221 ataaatctgt tttttgtgta tttcatctgt ataagctttc aatctcaaaa cagcaagatg
     2281 ataaatttct tctgcacttg cattcttttc ttcaaaatca tgaagatatt ttgcaagaaa
     2341 caagactatc ccggatattc catcatataa atatattcca cctgatctga gattccagtg
     2401 accattatcc cagaattgca gacccgccca gccggcgctc tgttcccgga taattgctct
     2461 gctgcagatt cgatgaacta tctttctgat ctgactgtat attttgcgct ctttatctgt
     2521 gtcatatccc tttatcctgg tcggaaacat ctttttcttt ccatcagatg ccttcagcat
     2581 ttccatggac agcctgatat aatcacactg acattccata tcagagtaac tcatctgctt
     2641 catatgcatt cgccatgact cataaggagt acagggcaga tattctttat gttctccgcc
     2701 atttccatca taaacagatc tgctgttcgc atcaatctca aagcagggta tatccatttc
     2761 cagaaggctg tcaatttcat aatcatgaat ctctttcata aaagaagatt ccccctcttt
     2821 gtgaatcaca ttcaaaagag ctttcctgca ttctcttgac ttcatataat ccggatgaaa
     2881 cgaagccata agatacattg catactgttg ggtatgccgc agtacaactc tggaacgtcc
     2941 gtcaaaaaag ccggacaaca tcacctccac tttcttatct gccattgcca ccatgtacgc
     3001 tctgcaaaat cctctgataa tgcattccgt ataatctgcc gcattgataa cctgatcatt
     3061 tagtcttaca atgcattcct ttatctgcat ttccacaggt tcatattcta tgtggatatc
     3121 agatgtttta tcatccttta ccacaggaag tttaaacggt gtttttatct tttcctctgt
     3181 tcccattgca cttataagaa ctcctctgtt tcctctgccc catgtgagaa caggaagcat
     3241 tcctgtatgt ataaccgaat ttgccaattt tatctctgta cttttgttta ttttttcttc
     3301 tacactactt ccgtctttct ctgattgttg ttttaaatat cccggatatg tctccatatc
     3361 gataatcaca ggatattctc catgtgcaat aatattttca ccatgaagat ctgttgctcc
     3421 gagggcatat cccaaaaaca gatgtatgcc cattctgaaa taataatgct ccacctcact
     3481 ttcgttttta cagggaatat tctcaatttt ttcttcccat ccataggaat catgagataa
     3541 atattgtacc gtcctgcagg aaattcctgt ttttctgcat aaatagttat aaagttcctg
     3601 atattttata ttcttatcaa gactatgtgg cttatagtac agaattgttc cattatccaa
     3661 ttctaccttc gccacacttc gtcctcctct gtgtatatcg cctttcgaca tgtaaattcc
     3721 cacagtcccg gaaaactttc ttccatcaca gaatattttt tgtatctgtt ctttttctgc
     3781 ataaagagat ttcctgattt cacattctgc tctctggata gagttatttt tcaattcaag
     3841 cagacgtttt aactcgggat attcctgcag taaagatttt acatatgttg cattgttaag
     3901 atattttttt tcataataat catattgttc ttttggcgta cttcctttta gatttccaaa
     3961 atttttctgc cgatgtacat ctaagattaa tattttaaga aacatagttc gattttttct
     4021 gcataaataa tccaatttca gcaacacact atagttccat atacaataaa agacaatttc
     4081 tcttctatac tttccgtatc tattatctct atttcatcta attctttttc cacatttcct
     4141 attattttat cattcatttc gttcataacc gtcactctcc cattatgtat tatcgctaat
     4201 tattatttct acttcaaaaa aatctttatc atatttaaaa tctatttcac cattatactt
     4261 tcttacaatt tgtttgacac tttcaatccc ccatccgtgc tcatctttct cttttttact
     4321 tgtataaaat ttagtgtttt tttcataagg tttatatatg cttgtattct ttactttaaa
     4381 aataaacata tcattaatat ttcgaaaaat acacgtaatt ttaccttttc cctcttcaca
     4441 cttttcagca gcttctattg cattatccaa aagatttcct aggagtacaa caaaatctat
     4501 gtctttcatc ggaatttttt ctatttttga atctacttta aaaaaaatat tcttttcttc
     4561 catttttcgc acttttatat tcaacataaa atttatttct ggaattcctg tccacgctac
     4621 tccactatat ctaatgcttt ctctcttgta atgattcaaa aaagtgatac atgaatccag
     4681 ttctccattt tccaggcatt cttttatata taaaagcaaa tgtttttcat cgtgcaccaa
     4741 acaccgatac cggtcatatg acattctcaa ttcttcatat tcttcttcca ttaatttgca
     4801 tctcatatct aaaatctgat ttctcatttc tagggtcttt ttttgaaact taacatatac
     4861 accaatcaat gctatattac taactgctaa taaacatgcg gtcattacaa aattttcctt
     4921 tttaatcgta ccaaatttgt atatgatgct aactattaat aaaacatact ctaacaatcc
     4981 aataataaaa agttccttca gacgtgtacg caatattcct tttatactgt ttactgacaa
     5041 aataaattta attatccaaa atatgaataa acagcctaaa atccaaaata taacttcctg
     5101 atatgtatgt cctctcggat atgaataaaa atcatcccac tgtttatggt taaacacccc
     5161 tgcatataca acataagcct cttttatcaa tcctatatta actgcataga aaaaattcca
     5221 aacatatgcc tgtttaaatg tgcaatcaaa gtagcaaaaa acatataata caattattcc
     5281 actcccaaga ataatcatta acaacgattg atatccagcc caatactgag cagttaacca
     5341 aaatatcatg ccgatatata atattcttct taagaccatc tcctttttct ttacaaaaaa
     5401 aatatcatat ataattcctg caattaatcc aattatgtat atacaaataa cttttatgac
     5461 atatttttct atttttttat caatctgcca taatgaaaca gaaaaattat aaattccaaa
     5521 aaaaatcaaa gaatacaaca gccattctag aacataatat tttttttcta atattcttcg
     5581 ttcagaaaac gtctggctaa atatccagac acctatccct gtctccataa acgttgccag
     5641 tccatacaat aaaactttca gcattcttca taccccccag taattcagaa ttgcttctct
     5701 gacacctttg aatctttctc tgccaactgt aataatatta ccgtcccgca tataaagatc
     5761 ccttcctttc atcttcatca catgttggat gtttgcaaga tatcctctgt cagatataat
     5821 aaattctttt gaattcagtt ccttttctac tgttgacaga cttgctctga tctttacttc
     5881 cccacgcctg tgcacaaaaa tgacatattt tccttctttt ttcatataga aaatatcaga
     5941 atatgccagt ttttcaactt catttctttt atttatgata tagtaccgct cttctttctc
     6001 cataattcca ggaagaagcg catcataagc ctgcggaagt ttttccttca gacactcttt
     6061 ggggatataa cgataggtgt ttacctcata tgcttctatt gcataatcca caaaatttgt
     6121 aataaatata ataaccggat ccggataaag tctgcgaatt tccctcgctg cctctattcc
     6181 gttttctcca ggcatccgga tatccagaat atacatatcg aatttttctt cattcaatcc
     6241 cagcagaaac cattccacct tctggtatat cgttaccgtg caatctacgt ttttctctgc
     6301 aaaatactgt tctgtgatat ccttttcttt tttcagatac atttcgtcat catccagaat
     6361 cattattctt atcatagcaa ttattcctcc atgaatgtat aaaatctgaa tttcttcaca
     6421 tcataaaaat aactttcatc cttattgatg accagctcat aaacctcgat atcccctttg
     6481 gttgtcacat cagttctgtg atactgataa atgtatctgc cttcctcatg gttttttacc
     6541 tttctgatga tatcatccac cagttctccg attgtcatcg gactgtctct ggaaggtctc
     6601 catcttccaa tcataccacg aacctgtgac ttggtcagtt taattctctt tccaagaaga
     6661 tatcctttcg ggaaaaagtc ttctctggtc tttcctgtct tttttaatat ctcacgtatt
     6721 gtcttatttt cttcatctaa agcaaatccc atattagcat aagcctgcat atgaagcaac
     6781 gctaattcga gatatttact gttttcagat tctttattcc ataacagtaa tttgtccaga
     6841 cttttatata cagtttctct gattgtaatt ccctgatttt gcaaagtctg caaagaaaac
     6901 atcatggtat acaaatcctt tgtatattcg tccatattcc tatattcctc ctgtcataaa
     6961 acatatcaaa tttgattagt cgcttgtcat ttatatcctt atacatattt aattccgtct
     7021 gttaaacttt atcaaaggaa aggattttta tttatgaaaa acaatactat cggaaaaaga
     7081 attgcagaag ctcggatcaa cagaaatatt acccaggaac acctggaaga attaagtggt
     7141 ttatctgtaa gtacgatcag ccggattgaa acaggtaagt atatgcctac tattgaaaat
     7201 ctccttaagc tttctgaaat tcttgatgtg ggacttgact attttcttta tgatctgctt
     7261 cctcataata aagatattca aagcccggct attcaggatg cgatttcaat catgaatcaa
     7321 atgggtgaac gccagactga atacattgta aaaatactga aaatatacca ggcctctcat
     7381 caggattaaa tataattaca attcgacaat tttcgtgttt ttgtcctcga aaagcatttt
     7441 tctgacctcg aagcaacaat caggaaatgc tttttatttt tttctgtttc atgtttacat
     7501 ttttcccttt tctcactctt tataagatgt atcaccggtg agcaaataaa taatcaaatt
     7561 tcaggaggat gaaaaaatga caaaaacaga aaaagcagta acatgggcaa ttagaatcgc
     7621 aaacgatccg gcacacggat atgatcagga taacagatgg ggaccggact acgattgttc
     7681 ttcactggta atctccgcat ggcagcaggc tggtgttcct gtaaaaacaa aaggagccac
     7741 ttatacagga aatatgaaat ccgtttttct gtcctgcggc tttaaggatg taacttccaa
     7801 agttaatctc agcacaggaa gtggcatgaa acgtggcgat gtattattaa acatcgcaag
     7861 tcatacagta atgcacattg gtaatggtca ggtggtatct gccagcaaaa atgaaaataa
     7921 tggatatcat ggtggtaaac ccggagatca gagcggaaaa gagatcaaac ttcagagtta
     7981 ttacaatttc ccctgggatt gcgttctccg ttatactgaa gattcttcaa ctactgatcc
     8041 tgatcctgaa cctcagccaa ctgcaggaaa tgcaaaaatc cgcaaaggtc agggttatgc
     8101 caataaattc gccaatgcag gaatctctat taccggaaaa agagacgctg ctaccaaaaa
     8161 agcaggcgtt aaagttcttc agacagctct gaacagggat tatggtgccg gtctggatgt
     8221 agacggtatc tggggaacaa acacagacaa tgctcttgga cagcattatg taaaaaatgg
     8281 tgaaacacag tatatggtaa ctgccgctga gattctcctt cttttacgtg cttatgatcc
     8341 aaacggtgta gagattcccg gtacctttgg ctcaggactt ctctctgctg taaaggcatt
     8401 ccagaaggca cagggcttaa cagtttccgg aacctgtgac agaaatactt tcctgaaact
     8461 gatcagctga tctttaccag ataaacatcc ggcagaattc tgtcccctga ttctgtcgga
     8521 tatacccctt cactattcat gtatataaca aaaagaagca attttgaaac ccattaaaat
     8581 ggtctcaaaa ctgcttcttt tcgcattttt atattctacc acggaacata ttcgccgctg
     8641 tcttcatcat aataatacca gccgtttcct ctgcctacag gactacagtc agattccgca
     8701 gcctgaaacg gtatatagga attggttccc ggatcccagg aatacaggtc atacggatct
     8761 gtgacctctt ctgatgcatc gtgaggtgct gtccagtaat atttattgcc atcctgatct
     8821 gtgacaccat tttcatttac catagcatct tcaatatctt cccagcttcc atagtaattt
     8881 ccgtcactgt cataccagtt tccatcatca gcttcagaaa tcagccttcc atttccctca
     8941 ctgtcatata tcattgcctg atctgccctc tgatcagatt gagtaccacc attacctgtt
     9001 gaaccattat cttcagatgc agaagtgtcc acccctgtgg tctgggaatc gtctgtatca
     9061 gttcccgcag tactgtctgt tccattctct gaattctgta cgtcgcctgc attattggat
     9121 gaagcagata ttttcgtctt cttatccgca gtctgatttg aatcttcttt tccaatggat
     9181 gtacttttat ttacctgttt tttatccggc tgagattttt ctgctgtttt ttgttttgtc
     9241 tgttcggatt tctcctgtga gttctgcgta taatcaacct gtgtctctgt tttattctgt
     9301 tccgcacagc cagtcatagc agccgctgct gctaaaatcc ctgccataat aattgcaatc
     9361 tttttctgct tcattttgtt atcctttcta catttgttaa aaatgtcgat gcctttatca
     9421 taatgtgctt ttcctgttca ttatgacata cttcacaggc ttcgatgcct catatgtccc
     9481 ttatctgtca tgaaatgtac cccatttttt tccaaaatct ttaccccata attttgcctt
     9541 ataaacgctt ggtaaaaggg gaatatcttt tttcttaaaa gtgaaatctc tgtgaaacaa
     9601 atggcagcag tacttatttc acaactattt tctttatttt cgaccatttc gtataacttt
     9661 ttgcataacc ttttacatag gcacgtcctg caaggtagta gactccgggc ttcacatttt
     9721 taaagaccac cgtggttttt gtctgatttt tctttgtgta agcataactg cttacaccag
     9781 tatagctgcc attatcagat ttggaaactt tctttgccag tacccagtct gttccatcac
     9841 aggactttgg aacagtaaac gtcaccgcca cgtttctttt tgttccctgt ctggaaacct
     9901 tagctgattt aacagcaggt tttcctgtta caaggcttgt ttttacagtt accttcctga
     9961 cctctgccca tttactgagc actttggtat tgctcccatt cagatattta taagcatgta
    10021 cgccaatata ccacgttcct gccggtacgc cccgtaagat aagctcttta ctgcttccgg
    10081 aatacccact ctttaccttt atataatccg atggttcttt tccgttctta cttctggcag
    10141 caacaacatc gtaaccgtcc ggttcctcac ccttgctgtt aagtactatt ctgacatcat
    10201 ttttcttcac ctgcaccttc tgaaccacag gtgcgtccgg agtctttgcc tttaccgtaa
    10261 ccggaacccc gtctgaccat tccccatatt ccataacatg gctgctgttc tctttgtatg
    10321 ccctgcaata aagactatgt gttccctccg gaatatactt cagctcagga tattgattca
    10381 gttcagaatt tgtaattttt gtctgcgcag tataattccc ctttttcaga tccttctgag
    10441 atttcgctgt cacaaactga tagccgtccg cttcattgga aagatctctc agataaagca
    10501 ttgcataatt tgtgatcact ctggtccacc gcgtatcaat aactggtctg tttaatgtct
    10561 gataagcatc cacctgtacc attatctgta cggcagtgtc cagcccttca ttattttcat
    10621 cctcattcag ttccagagat ccgttgacca gaaaactttg agctgccttg cttttcggat
    10681 cataagcaca attctccaca tcccacttca cagacgcaga aaatgttgtt ttctctccat
    10741 tcacctcggc gccatagact tccagcgact tcggcagatg caaagcatca gcagtttttt
    10801 ctgcaccatt ggtaattccg gtcacaggcg caacagcatc tgccagtccc tgataagtcc
    10861 ggtctcctac aataaaagaa ttatacagat tctgcgttgt caggtgttct cctgccactg
    10921 ttttcgcagt cacagtcacc tgaaaactat attttcccac cgaaagcccc agtttgggcc
    10981 agagtctcag ttctgtgctc tccccaggtg ccagataagc atttccagat aataacacac
    11041 tacattcttt actacggtta aaagacagct tcatatctgt atcagtaaca tttttcagaa
    11101 tatatgtctt tgcttccgga agtgtcttat agccccactg cattgtcgga aaacccccgg
    11161 cagacttttc agtaatttcc agctgcttct tttctgtcgg attcttctct ctgttcattg
    11221 taacatgaag aggatatctg cttccgtcat ctgcgagaaa tgcaaacgtt tcatcataaa
    11281 ttccgtattc ctgcttcggc aatatataaa aataaagcgt ttctcccggt ttcagcagct
    11341 ttttggaatc ctgttcctca taatcttctg tccactttgc catctggtca tccacttcaa
    11401 aattcttaag accagaagta tctatccgta ttctggtttc cttttttcct gaatttctga
    11461 ccactacata cttctccaca cgaaattccg ggtcatagaa atcgctttct gtaaattctt
    11521 cttctgtacc tgtttctata ctcagctcat aatctttttc agaggaagct cccacaatta
    11581 ctttcagagt aaccttacag gaagcaccct cttttgtctc aaatgtcact gtctcttcat
    11641 aatttccggc aggcagattc ttcttatcat caatgtccac agccgcacaa cttccgggct
    11701 gcatttcttc atccgtattt gtatcgaaaa tcggtgcgta ggaaaaatca aaatatctgc
    11761 tctgcggaaa atcagagaga tgaagcgaat ctgttcctgc attataaaga aataaccgct
    11821 tacgtgactg ttctccctct gcatgaattc ccagatcgat caaagcagta cctgatgtca
    11881 gctcatactg ctttataaca ggttcctgct cacgctgtgc aacataaagg ctcagttcct
    11941 gtgaagaaac tccaatacca ttgtccgcct gtacagtaaa gctgaaactc ccttcctcct
    12001 gtggcattcc actgatcact cccccggaag acaacgtaaa tcccgccgga agctcacttc
    12061 cctcttccag actccagttc acatctgtat cagcttcaag ctgtacctga tattccgttc
    12121 caatctctcc atccggcaga accatatctg tcaatatggc aggaatactc cccgttccat
    12181 cactgaaaga ttctcccgcc gaaaaaactt ccgccccaca tactgttaac ggagctgctg
    12241 ctgtcataat tgccgataaa aaaactgctg taaaaatttt gtaattactt ttcattcttc
    12301 tcctccagat aataaaatat aaaagtatca atttacctaa ttaatattaa tataccactg
    12361 gacgggaatg tttctgtaat tacggaatga catgttgtat aatggtcatg aatatcagaa
    12421 aagccagtaa tgtttcgggt atatgtcaaa aacattactg gtctttttta taagattatt
    12481 ccacactttt tattcgatac agggaatctc ataattccag gatttacgga tgtcgtccat
    12541 gattttcatg atccttattg tttccgcatg aggcatttcc ggacactccg tttttccctc
    12601 atgaattgct ttcatgcagg attctacctc atattcatat cctgagatct gttccggcac
    12661 aacataagaa gccacttctt tatgttcggt atcaaacact gtaatctttt ccggattatt
    12721 gatattctgc acctgcatat atcctctggt tccgaaaata cttcccattc tgtctgagat
    12781 ttctcttgct ccacactgaa gggttgccat gcggtctccc tcaaacacca tggcaatgct
    12841 gtccagaata tccactccat tctgaaagat tgcagtagcc tttacatcct ttaccttatc
    12901 gccaagcacc atggaggcaa aattgatcgg atatacgcct acatccagaa gagcacctcc
    12961 tgcaagctcc ggtttacgga tacgttccac atgacttact gtatagctga gattcgcggt
    13021 aactgccgta acttctccga tcacaccact ttcaataata tcgttgatca tctttctgga
    13081 cggcatatat cttgtccaga ttgcttctgt gatcagaagc tttttctctt ttgcaaggtc
    13141 aaataatttt tgtgcctgct ctgcatttac agtaaatgcc ttttcacaaa gcacatgctt
    13201 tcccgcttcc agacacattt tcgcatgcag ataatggtgt gaatgaggag ttgcgatata
    13261 aaccagtcca acctcatcat ctgccagcat ttcctcatag gatccatatg ctttttttac
    13321 ttcatatttc tgtgcaaata cccgggcacg ttccagatca cgagcagcaa ccgcatacgc
    13381 ctccacatct ttcattcctg ccactgtttt cgccatagta gaagcaatgc ctcctgctcc
    13441 cagaatacct aacttcattt tactgtccgt tactgaaaac ttataaaaag ttataaactt
    13501 ctatgtttca ttcctacttc aacgagtatg cttttgatga tataaatatc tatctactca
    13561 caagttcttg taccctccat aggcgtaaat tccggactaa cgtatccgta catatttgca
    13621 ttaacgtttc agtgtcagcc tgcaaattgt tctccataag tcttgagatt tatagatgcc
    13681 tggaaatctc tgtcaatcat attc
//
