LOCUS       c00042_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FKHCHIMF_47.
ACCESSION   c00042_gnlPro..
VERSION     c00042_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:24:30
            Original ID  :: gnl|Prokka|FKHCHIMF_47
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 10699
            Orig. end    :: 33948
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[20699:23948]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(155..1246)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_11"
                     /sec_met_domain="Peripla_BP_3 (E-value: 3.1e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
     CDS             complement(1438..2325)
                     /locus_tag="ctg42_12"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSK
                     MAGVKNRAGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             complement(2322..7019)
                     /locus_tag="ctg42_13"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAATSKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQFLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARSVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVAEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLNVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGETETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEVVFKTESTEPEKIVNTAKA
                     RGDISPEIAAQQEVYVKTKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGNGGSSYGNSGGYGSYQGGSMAGSS
                     KTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             complement(7222..7683)
                     /locus_tag="ctg42_14"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGKAVVIAAAAVIIVLLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             complement(7883..8761)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_15"
                     /sec_met_domain="CN_hydrolase (E-value: 8.2e-56, bitscore:
                     181.1, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVHQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             complement(8863..9966)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_16"
                     /sec_met_domain="PAD_porph (E-value: 1.6e-127, bitscore:
                     417.0, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGVSEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGTFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTQED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             complement(10001..11122)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_17"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 6.4e-15,
                     bitscore: 47.2, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TEQLKKFKEVCTGASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIQIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             complement(11112..12392)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_18"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 2.2e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.9e-35,
                     bitscore: 113.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKIDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             complement(12389..13249)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_19"
                     /sec_met_domain="Spermine_synth (E-value: 1.8e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 2.7e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             complement(13252..14709)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_20"
                     /sec_met_domain="OKR_DC_1_C (E-value: 1.5e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 3.2e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVERLQVLKGGI"
     CDS             15934..17619
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_21"
                     /sec_met_domain="FTHFS (E-value: 2.8e-275, bitscore: 905.6,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKRVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             complement(17728..19152)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_22"
                     /sec_met_domain="Lyase_1 (E-value: 1.4e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 2.2e-21, bitscore:
                     68.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRRLILKEKLMDDDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             19268..20203
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg42_23"
                     /sec_met_domain="LysR_substrate (E-value: 1.9e-33,
                     bitscore: 107.5, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.1e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFERYIYQKEQ
                     LLLAVPKNYSVNTRLQKYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             complement(20315..21772)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_24"
                     /sec_met_domain="FGGY_C (E-value: 3.9e-38, bitscore: 123.0,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 2.5e-80, bitscore: 261.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARNLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
ORIGIN
        1 aacaatgatt ctggaatgct cagcaacttt tcttaagcac tcatctccgt aaagatcctg
       61 tgaacctgta caaaaccaga acttatagtt tcttcctgtt ttcatgataa aattcctccc
      121 ggatttattt ttatttttta tttatttcat ttgtttacaa tatttttctg catgatcccc
      181 gtatgatcag ttccggataa atcagtcttt caaccttact ttcttcttca ggaactccgt
      241 tgatcttctc aagtataagc tctgctgcca tttctcccag cttttcctgc ggatgagcta
      301 tcgttgtgat tccgcttcct cgctgagcat acagtgaatt gtcataaccg gtaatggaaa
      361 tatcatccgg tatcctgact cccattttct ccagttcttc cataacctga acagcaatct
      421 gatcattgta acagacgatt ccatccggaa gctgtccgct ctgtaccatt tcttttgcca
      481 tcagtgcagg ttttactttc ctgtcctctg tatgaaacca gacaacatca tcaggatcat
      541 aggcaatccc tgactcctgt aaggccttca catatccctt gtggcgctcc agtccctgca
      601 tatcgtctgc cttaaagaaa cccttgatct ttttatgtcc cagttccagc agatattttg
      661 ttacaagata gcctccctgt gcatcatcca taagaatatg aggtttatcc ctcatttctg
      721 aatagattcc ctgaataaac acatacggaa tttcaaattt atccagattc tgataaagat
      781 ttctgtgttt acagatcatc tcacttttgc ttggttcaat gatcagtcca tcaatatctt
      841 tcttcagaag ttcctccaga catctggcct ctttctgtct gctgtttgct gtgtttttca
      901 ggataatact gtaaccgctt tctgaaagga cattatccat tccctgtatc agtctcggaa
      961 aaatataatc agaaatatat gtggtcacta ccgcaatatt ctttgaattc tttatatggc
     1021 gcatattctc agagcaataa gtacctcttc cgtgaaatgc ctctacatat ccgtcctgct
     1081 ccaggattcc cagtgcttta cgaactgtat gtctactcaa ggaatatttc tgtgaaagct
     1141 cgttttctga aggaagcttc tctcccggtc ggatagctcc tgacataata tcacttctga
     1201 gctgttccat cagtgagaaa tatttcggct ttccattatc tgtcatgtct tcttccctcc
     1261 tgtatttagg atacaacttg tacgcacgta cgaacaagtt gttttttatg cataaattat
     1321 acaaaatatc gagagatttt tcattagttt tttccaaaac acctcgaggg atagtgatgt
     1381 gtgaacagta acagttcatc ctttacgaaa gttaccaata tccgattgat ttcaacatca
     1441 cttcggctca gctttttcta taccataaca ttcatggcaa atcccatgta ccgccatacg
     1501 tatttcttta tccagacgtg aattacaggt gatcagagtc accattctct ccctttcatc
     1561 aggctctact cctgtgtcat acatggaatt atttttcaat atagataatt gtctcctgta
     1621 tgcaggactg gataacttgt atccatattc aaatgccggg ctttgggaag atgcctgttc
     1681 cacagaaaaa attttgtaca gaaactttct ttttggtgtt gtgatctcaa tttcaggaca
     1741 tttttttaga aattcaggct gttcataacg gttcagattt gcaaacatca tattaccttc
     1801 tatattatgc ccgtaaagaa tactgtggga atctgtgaaa ttctttttta tgtcatgttc
     1861 cagaaaaata catccaaaca gatcttcctc tcctctgaaa ttatgtttca ggtaatattc
     1921 atcatctgcc gcctgaacta caggataaga aatatcggct cccgggacag taatccaggc
     1981 aactgtctga gagttgatct ttcttaaatt ttcccaggaa atcccgaagg attccctgat
     2041 ttcatctgta cagtttttgt tttttgattc agaagatctt ctctgttttt tcctgcgttt
     2101 tttttcactg ttttttgtac tgctgtcttc atcagttttt ttgccatctg ccaataatcc
     2161 ggcacctgct ctgttcttca cccctgccat tttggaaagc tctgcatatt cctgccttgc
     2221 tgcaagattc tgttcataac tttttatata gaagccggca caatatataa gaagcccaat
     2281 tgctgctatg atcatactta ctgcaaatgt tctgagtttt ttcatttccg cggcataccc
     2341 tttatatttc ttttcccgga aacagttctt ctgtagatca ccacacctcc tgtcagcagt
     2401 cccattccga taagtccaag aacagccatc attttaaacg gtctgacatc tcctgtttta
     2461 gaacttcctg ccatggaacc accctgatag cttccgtatc cacccgaatt tccgtaactg
     2521 ctgcctccgt ttccggaagt tgtgcctcca ttatttccac cattgtaaga tgccaacggt
     2581 gctttcgtcg gtacaggagt cattttcggg caggttcccg gtacagatgg tgttggtgtg
     2641 gcttttggct gctccgtcgg tttcggtact tctgtaggtt ttggtgtctc tgtcggcttt
     2701 ggtgtttctg ttggtttcgg tgttgcagac ggtgttggtg tggcagtggg ttctgctttt
     2761 gttttcacat atacctcctg ctgcgccgca atttccggtg aaatatctcc tcttgctttc
     2821 gctgtgttta caattttttc aggctctgtg ctttctgttt taaataccac ttcatagcag
     2881 acttcaattt tatccatatc tgacaacgat gctcctgtct gaattacaaa tcctgtatca
     2941 tctgcctcta ttttggcatc tttcagctct atgccgtttt tcttcacaaa aatgctgtct
     3001 tttacaatag aagccccttg ggtttccagt ttatcttcga taacaatatt ctgatctgtg
     3061 acatcctcac gcagttgtct tactgtcagc ttatagtatc ctttctcacc ggacgcatac
     3121 tctttcttat ctgattcctt cacaatttcc agaatcggac tgtgtacctc tgtctctgtt
     3181 tccccggttg caggtatctt ttcactgctg tctgcaactg cagtattgtg cactttctgt
     3241 cctgccaggg ctgcatcaat cactgctgcc tgatattcca cgatcatact tttctgttcc
     3301 tgacagtcca gaggattata cattacctgc tcaaaaagac cgcctttatc attatcgcag
     3361 atactatatc tgctgtccct gaccagtgtc ctgcctgttg acatcaggaa agtattatca
     3421 tcattgatct gtacatcagc atctgccaca tttcctttct catccatcag aatcaccgaa
     3481 tccttcagaa gacgtactcc ctgagtatcg atcacatcct gcagagtaac attacgcgcc
     3541 acacatccgg tctgctcctg tgtcaggaca atgcggtatg taataatatc accatatttg
     3601 taaaatggtt tgtccgtcgt cttctctacg ttaagaacag gcgagttcac ccagattttt
     3661 gaggagtcct ttactttctg tgcattatct gcatacgcct gtgctgtatt tacaatctcc
     3721 atcccattta cgctttcctg cgcagtacag cggaaattaa cagtcacagg tgtctgatac
     3781 ggaagatctg aaatcgtcac gatccatccg gttccctgac gtgtaacctg acagctgacc
     3841 ggtttttcca ctgtttcttt ataattttcc ggattcagct gatttcctgc atcatcagtt
     3901 cctgccaccg gattctgaat aacagccgga acaccgctta cagtaacagc atcttcagct
     3961 ccgtccagag ccagcccttc aggaagggaa agatcactga tcacaagatt tcttgcgata
     4021 gatcccttct gaagattatt aaccgtaacc tgataattca cctgttctcc tacccgaaat
     4081 tcattttccg cacgtccgtc cccggctgcc agatatggat tctgaaaact tttctcaata
     4141 gaaagaactg ctgtatttac atacacttct gcgtcatcct gtgaaacagg ggcattctgc
     4201 gcctgcacat tggcaacatt aatgctttcc attccatttg ccgcttccgc aactgtgcaa
     4261 aggaaagaaa tcataaccgg agtatttgcc ggaagatctg aaatgttcag tctccatccg
     4321 cttccctcct gaagaaattc ataattcacc ggtttctctg atgtctcatt ataaaattcc
     4381 ggattgagct ggttcaaaac atctttggtc cctgctgtca gctgcgtaat attctgtggg
     4441 attccgctta ccgatacatc ctctgccgat gaaagcgcaa gtcctgccgg cataccggta
     4501 tcccagacag ttacgttccg ggccactgta cctgcttttt tattctccac caccacattg
     4561 tactgtacct gttctccgac ctgccattca taatgatctg cagatttctc aatccagaat
     4621 tctcctgaat ttacatatac ttctgcatca tcagatctct catctgtatt agcagctttt
     4681 acagttgctg catttacgct ttcgtgtcca tttgcctctt cctgtgcgat acaatggaaa
     4741 ataatcgtta caggctgact gtatggcaca taagaacaat aaaaggaaaa tccgttctca
     4801 tctgcattca actgagaatc cacagatctc gcttcatatg cctgtcctgt tttcttatcc
     4861 ggtacgggat agtttacctg ttgctgaact cccagtactt ccatgctctg tgcaccacct
     4921 gccagaacca gtccctgcgg cagaccaata tcagtaatag ttacatcttt tgcaattgtt
     4981 cctgccgtta cattattcac cacgatccgg taagctacct gctctcctgc ctgccattca
     5041 tatttgtctg ctgttttatc aatttcaagc tgtggactgt tcggccatac ttctgccata
     5101 tcctttctgg attcctgttc tcctgtctca ggattgatca gattatccgc tgttgcagtc
     5161 acaatatttt cccattcctg tccattggaa tccgcagatg cctgacattt aaaacggatt
     5221 gtgatcgtct ccccatactt cagggacgga cactctgctt tccatccatt ttctccctgt
     5281 ccggtaagcg tacagttctc gcctccctga cttgtctcta cagcatactg cccttccaga
     5341 aactgcagac atgatggaag ctcgtctgta ataacaacat ttactgcttt tacatcctgt
     5401 tttgtctgag aaaccagaac ctcataatct atgatatctc ccgttttcca ttcatactga
     5461 gaagtatttt tctttacttc cagttccggt ggaatcacac cctttaccca cactgtttcc
     5521 gtatccattg tatctccgct tccgtttgta cgttcataac tcatggatgc atggtttggt
     5581 acaagaatac tgtatccatc ctctgcaagg tattttgaaa tgttaatttc tgattccggt
     5641 ctctggcgta cttttaaagt aaatgtgtaa gtctgattat ctgtaaatgc ttcatcctga
     5701 aggctctctg ctttggccct gcaggtcact ttctgtcctt caacagcaac atcaaaccag
     5761 tctgtcactg tctgccctgc atcattcaca atactgactt ttgatgcatc ctctatagta
     5821 agacaatcct caagtatatc ctgtaccaca aaggatttca gtctattggg tgtcacctcc
     5881 gcccggatca tatactggaa ttcctgtccc tgacgaatgc caaaaggttt ttcttttgat
     5941 gtggcagctg cctgttccca tgtacagttt gcctctccca cacgtttctc aggcgctttt
     6001 ttcatctcaa catcaccgaa acaataggat gtaaaatcaa aatatgcata tgctttgcag
     6061 tatttctgtc ctttaaagtt cggacaataa ctgttgcctg atggatccag atatttattt
     6121 cttgtaatct ctgcccatct ttcctgagaa ccggcttttg caatggcatc ttcacgactt
     6181 ttatcccatt tatccagtct gaactgatga cagaattcta ccgtaaaatt atctgtatta
     6241 taaaaaagat tcagccatcc tctcggatca tccggctcaa cggaaccaag gggtgagctt
     6301 acagaattcc catctaccgt cagataatca ttgtttttca gaacatatgc attatccaga
     6361 ctgctgtctg acggaatacg gactccctgt cccgcatcaa tatcacgtat ggttccatgg
     6421 ccactgatcg gcagtgtttc ttctgttcca tgcttcagaa actgaaactt aacctttgcg
     6481 tatcctacag aataaataaa tacaccgata ctgtttttgg aaaagccaac cattggataa
     6541 gcttcattat ctttccatgc aaacgtagct ccgcctttat tctgaacaat cgattctgca
     6601 gtgcgcagat cataacgggg ttctgcattc tctactccca caagaatgag tctgacatca
     6661 acaatatttc catttccatc ttttcctaca ttgttataac gcatccctgc gcttccggct
     6721 ttatagtccg ctcctacacg aacgcactct gtgtcacgtt cactttttcc attgtctgaa
     6781 aaagcttccc tgtccagatt atcacaccca aaagattcat atgtggtaat tccgggctga
     6841 aacttcatgt taaagcgata accataatct accaccttgt cactgtccca tgtttctaca
     6901 gttaacggtg ccgcctgagt tacgcagaca ggcacaagcc ccagaattgc ctgcagaata
     6961 aaaagcattg caagcagcaa agctccaagg cgttctttca gtttgaaatt gtgtttcatt
     7021 ttccgtctcc tttccgaaca aaaaatataa aaatgaatgt gggatttttc cctgcacctg
     7081 gcaggattaa agaatagaaa taagttgaga ttgtatgatt ataaatattc aaggggaatt
     7141 aatatcgtga aacaagaacg tttacactta agattttaag attctgcgca gggtttcttt
     7201 tctgaaaccc tgcacagatt ttcattgatc atttcttttc ttcagccatg aaagaaaata
     7261 aagaataatt gcaagaataa taaaaaacgg aatcgcaact ccgattatca gtatcagtaa
     7321 aacaattata acagccgccg ctgcaataac aacagccttg ccatgccagg tagaaagatc
     7381 gattactttt ttccatcttt tctcctgctg atgaggaagc tctgtctcat tgccataact
     7441 acttccgtaa gaagaatact ctccgtaatc ttcctgtgta cttccatcat ctgtatcgat
     7501 cagagttttt gctatcagat gcgggtctcc cagttcctgc agtacttcct gctctgaacg
     7561 tccgccacgt acctgagact gtatataatc ttcataatac ctgatatgtg ctgctgcttt
     7621 gccctcctgc atctgcccgg caagctggct tctcaggatt tccaaaaatt cttttctgtt
     7681 catcttctac actccatttt gccagaaata catatcaaaa ctctactgct ctctccgtta
     7741 tcagtaacgt tcgtactctt attttaccat atataccgca ggtagcaact aatataatca
     7801 taaacttttt atgaaattct tataaacaca tatatcgttt tggaaataac actgcaaatc
     7861 cactcggatt ctcctgcttt cgtcattttc cgacaatttt tgcatacatc tccggtctgc
     7921 ggtctctgaa aagtccccag ttcagtctgt ctgcctttaa tgcatccagg tcaaaagtgc
     7981 ttacaagcac cccctcttcc cctccgggca gttctgcaca gagagcacct gtgttgtctg
     8041 tgataaaaga agagccgtaa aaattaagag cagatttctg cattccgttt tccggacatg
     8101 gctctactgt ttcctcaccg attctgttgg cagcgatcac agggatcagg ttggaggcag
     8161 cgtgtccctg catacatctt ctccagtgtt ccatgctgtc gcattccagg atgggttcac
     8221 ttccgatggc agtgggataa aagagaagct ctgctccctg cagtgccata catcttgccg
     8281 tttccgggaa ccactgatcc cagcagattc caactccaat ggttccaaat ctggtatcaa
     8341 aaaccttaaa gccggtatct cccggtgtga aatagaattt ttcctgataa taatggtcat
     8401 ccggaatatg tgttttccga taaatgccga gattctttcc atctgcatcc agaaccgcaa
     8461 cgctgttata agtattattg acctcttttt cataaaagct gaccggaatc acaatcccca
     8521 actctgccgc taccctgctg aaatgacgca ctgcagggtt ttcctctgca gtctgcgcat
     8581 attcataata ctcatatctg cgctcctggc agaaataggg ccgttcaaaa agctccggca
     8641 gaagaacaat ctcagctccc tttgctgctg cctgatgcac cagttcctct gcatgggcaa
     8701 tatttttctc cacactttta ctgcatttca tctgaactgc tgccactgtt acatttctca
     8761 tcctgtctgt tcctcctgct cctgtttaca taagtaagtt ttttcataac tttcaggtaa
     8821 taaccctcaa acacatgact ctcaaagttt tctgcatcaa ggtcagatat tttttccggg
     8881 aatctgctgg gtgatacagt gaatatttcc accgccaaca atgatggctc tggcatcaat
     8941 gggataaatc cttctttcag gaaaacactt ctgcagaatc tccactgccc ttttgtcatt
     9001 ttcatcccca aattgtggaa ggatgatccc tccattggaa atatagaaat tcacgtaact
     9061 ggcagccatc cgttctcctg cttcccgttc gtcttctccc tcttcaaaca caaagccatc
     9121 cacatcttcc tgggtaaggc agaccggttt ctgaggaatc ggaagcttat gaatcttaaa
     9181 ttttctgccc tttgcatctg tttcctgttc cagcaccttc agatcagcca aagacatggc
     9241 atactgcgga tctgtctcat cctctgtcca tgcaagcaca acctctccgg gccttacaaa
     9301 agcgcacacg ttatccacat gctcattggt ttcatcctga tagattccac atggaagcca
     9361 gataatcttg tggacaccga gccagtactt caactgttcc tctatctgtt ccctgctcat
     9421 ctgaggattg cgtccctgac tcagaagaca ggcctctgta acaatcagag tcccctctcc
     9481 gtcagaatgg atggaaccgc cctccagcac aaaaggtctg gcatccagac atggacaacc
     9541 gagagtcctg cagataaagg cagccaccct gtcatccttt tcccagttcc ggtaaagccc
     9601 gtcaaaggta cctccccagg cattaaactg ccagtcaact ccacagaccg cccctttctc
     9661 atccagaacc atggttgctc ccacatctct ggcccaggcg tcatctgtct cgcattccag
     9721 caaagtcaca ccggaaacat tcccaagctg attctttgca ttctccatct gagctttgga
     9781 aaccagcata tacacctttt cgctcactcc aatagcctct gcaactttca caaatgcttt
     9841 ctgtgcttcc cttgccccat aattccagga accgggacgt tccggccaga tcatcacaca
     9901 tccctcatga ggctcaaatt ctccgggcat acgatatttt gttctgttct tctctgtaac
     9961 ttccatgtct gtctcctttt ctttgatagc ccggcagata tcaggaaagc cggctcttaa
    10021 agtcttcgta tccgaaatgt ctgataacct cacactctcc gtcctcatgc ataaccgcaa
    10081 tatccggcag cggcataccg ttaaatgtat tattcttcac catagaataa atcgccatat
    10141 ccataaaata cagcttgtcc ccgatctgga tctctctgtc aaaggaataa tctccgatca
    10201 catctcctgc caggcaggtg caggaagata agcggtaggt atatgccttc tcccctgctt
    10261 ccccgctgtc cttaagaggc ggacgatagg gcatctccag cacatccggc atatggcagg
    10321 ctgcagaagc atccaaaatc agcgttctga tctcattttc cacaatgtcc ataacctctg
    10381 tcaccagata tccagcattc agggcaacag cctccccggg ctccagataa atatccagat
    10441 cataggtttc cttcatatgc tgaatacatt tttccaggag ctttacatca taatcctctc
    10501 tggtaatatg atgtccgccg cccatattca gccaggaaac ctcagacaga aattctccaa
    10561 acttctcctc taccgcctgc aatgttttct ccaggtcatc cgcattctgt tcgcagagcg
    10621 tatgaaaatg cagtccgtcg atccatttca gacattcccc gtcaaagttc tctctggtaa
    10681 cccccagcct tgaacccggc gcacagggat catagatcgc atgatccccc tgagtggagc
    10741 attccggatt aatacggagt cccagactgg ctccggtaca cacttcttta aatttcttca
    10801 gctgttctgt ggaattaaag ataatatggt cacagatccg atccagttcc tctatatctt
    10861 ctgtacggta agcaggggaa aaaacatgat tctctttccc catctcttca tatccaagcc
    10921 ttgcctcaaa cagaccgctg gcagtggtac ctgccagata ttttccgatc atgggataca
    10981 gagcaaagcc ggaaaacgct ttctgcgcca gaaggatctt acacccggta tcctcctgga
    11041 cttttttcaa aatctccaga ttctcccgca tcttcttctc atcgatcaca tagcagggag
    11101 tttgcagttg atcaatcttc attggctttc cagaccttta ccagttcagg atcttcgcag
    11161 actttccatg gaagtcccca tttgttcagt gcttccatat atggatccgg atcaaattct
    11221 tccacattaa atacacccgg cttcttccac tgtccggtca ctaccatcat ggaaccgatc
    11281 atagccggaa cacctgttgt ataggagatt gcctgggatt ccacctcttt atagcattcc
    11341 tgatgatcac atacattata aatataaata cttttctctt ttccgtcctt aacacctgtg
    11401 aaaatacagc cgatatttgt tttacccact gttctcggac ccagagatgc aggatccggc
    11461 agaagagctt tcaaaaactg aatcggcacg atctcctgtc cattaaattc cacaggtgcg
    11521 gtggaaagca ttcctacatt ttccagacat ttcatatgtg tcagatagct ctgtccgaat
    11581 gtcataaaga aacggatcct ctgtactccc ggaatatttt ttgccagtga ttcaatctct
    11641 tcatgatgaa gaagatacat atccttcttt cctacctcag ggaaatcgta gacagattta
    11701 aattccatag gctctgtttc tacccaatgt ccgtcttccc agtaggaacc atttgcggaa
    11761 acctctcgaa gattgatctc cgggttaaag tttgtggcaa aaggatatcc atgatcaccg
    11821 ccgttacagt ccagaatatc aatggtatgg atttcatcaa aataatgctt cagggcatag
    11881 gcactaaata cactggtaac acccggatca aaaccggttc ccagaagagc agtcagtcct
    11941 gcttccttaa atttctcatc ataagcccac tgccaggaat aatcgaaata tgcagtaaag
    12001 cctttttctt tacatctctt ttcatagatt gcacgccatg tgggatcttc tgtatcctct
    12061 gcttcataat tggcagtatc aatataatcc gcgccggctt ccagacatgc atccatgatg
    12121 gtaagatcct gatatggaag tgccacattc aggacagcat ccggcttata ggctctgatc
    12181 aattctgcga cctctgctgc attatccgca tctatctttg ctgtctcaat ttttgtcttc
    12241 gttgtacttt caatcttctc tttgagtgca tcgcattttt cctttgtcct gcttgcgatc
    12301 ataatctctg taaaaacatc gctgttctga cagcatttgc gaattgccac tgaagctacc
    12361 ccaccacatc cgattaccaa taatctgctc ataaactgtt ttcctcctct tccagtaaat
    12421 cttctacata ttttggaagc ataaatgctc ctctgtgaag gtttgttgta taataccatg
    12481 tttctatatt aagattatca aacctctccg gcctgaaatc ttccagtgga tgatatttct
    12541 ttgatgcaaa tccaaaaagc cagtatcccg agggacaggt agggatatgt gcctgataaa
    12601 ccctgctcac cggaaatgac cggaatacct ttctgtgcat ctttctgcat tccacctcat
    12661 cctcatcata aaaaggactt ccatgctgat aaaccatgat tccgtcatct ctgagagcct
    12721 tataacagct tccgtagaat tcctttgtaa aaagtccctc tgtatgtccc agcggatctg
    12781 tggaatcatt gatgatcagg tcatatctgg cctttttatt ccgcaggaac cgaaggccgt
    12841 cttcataata aatgttgact ctctcatcct tcagtccctg ggcaatatcc ggaaacatct
    12901 ccgcacatac atccacaaac attttatcgg attccaccac atcaatgctc tcaatctgtg
    12961 gataatggat cagttctctg gcaactccac cgtcaccgcc gccgatgatc agaacatttt
    13021 ttacattggg atgtactgtc attggcacat gcgtaaccat ctcatcataa ataaattcat
    13081 ctttatcaga gaatacaatc tcaccgtcca gagccacaaa tctcccaaat tcttcagact
    13141 caaacacatc gattctctga aattcacttt cccctgaaaa taactgtcgg ttaatccgga
    13201 cagaaagctt tacatttcct gtatggaact cggaatacca taattccatg atcagatacc
    13261 ccctttcagg acctgaagac gttctacctt cggatcctcc attccctgca tggaacagcc
    13321 tttgtctctt gcataaagaa tgtattctac aatttcctgt gtcaccattt ccccaggagc
    13381 aagaatcggg attcccggag gataacacat aacaaattca ccactgatcc tgcctgccgc
    13441 ctgttccatg ggcagagatt ctttctccgc ataaaatgcc tgctgtggag acgccaccac
    13501 tgcaggtgcg atatattccc cggaaagcat acctgtgctg tccttcttat acagacgttc
    13561 aatatcagcc aatgccccta ccagtctctc aatatcctga agcctgtctc cgatggaaat
    13621 gtaagccaga atattacaga tatctccaaa ctcgatctga atatcatatt catctctgag
    13681 aagatcataa acttcaatac ctgccagccc atttcccagt gtataaatag agagttttgt
    13741 aacatcaaaa tcaaaaacac tggttccatt gatcagatcc ataccatatg cataataacc
    13801 gccgatctca ttgatctcct ctctggcata ctgcgccatc cctgcaacct tttcaaagga
    13861 ttcctctccc ctgagtgcca gatttcttct ggagatatcc agactggaca acagaagata
    13921 agaagcgctt gtggtctgag tcagattgat gatctggcgc actttctctg cattcatact
    13981 cttattcaaa agcagcagcg aactctgtgt cagacttccg ccggatttgt gcatggaaac
    14041 tgccgccatg tcagcacctg ccgccattcc ggatacagga aggtttctgc cgaaataaag
    14101 atgggttcca tgagcctcat ctgccagcac cttcattcct cttgcatgag ccttctttac
    14161 gatagtccgc agatccgaac agattccata ataggtaggg ttatttacaa gaactgccac
    14221 cgcatccgga ttctcatcca tagccttctc cacctgactg acttccatgc caagggaaat
    14281 gcccagctgc gcattcacct ccgggtttac ataaaccgga attgcaccgc acagtaccag
    14341 ggcattgatg gcacttttat gtacatttcg cggcagaatg atcttatccc ctgccttgca
    14401 gacagacagg atcatgctct gcactgcaga tgtggttcct cctaccataa ggaatgcatg
    14461 cgctgcgcca aaagcatctg ctgcaagctc ctccgcttct ctgatcaccg aaaccgggtg
    14521 gcagagattg tccagcggct tcatagaatt aacatccagc cccacacatt tctctcccag
    14581 caactgtgca agctccggat ttcctcttcc tcttttatgt cccggcacat caaagggaac
    14641 gactctcttc tttcggaaac gttccagtgc ttcatatatg ggcgcatgct gttgtctttc
    14701 ataatccatt tgacatgttc ctcttttcct gtcgtcatgt accggcaaat acagttctat
    14761 cattcagcaa ttgtatactg cctcaaaccg gcacaatgat tcaattattt ctctatatat
    14821 ttgctatatc tgcacaaaaa aagaagcaga taagttcatt caccatctgc ttctctcatg
    14881 atctatagaa tttctcaggc tctgtctctt tatatactga ccggatttcc cgtataaatc
    14941 cgtctgtatc ctgtgcctgt tcccgtattc tgaaatattc atgactgctg tcgtcttcaa
    15001 tcgctggcaa atatatgcta tgctcttatt gaccgtttca caagatgatg tgtgcttacg
    15061 cactgattat tataaagtaa tcaacttata aaatttgagc ttctaactca atcaataatg
    15121 tggtgtctcc cacccggcaa ctgccccgcc tgtccgtatg gcttaacatt cagaaactgt
    15181 ctctgaatgt gagcaaatat ttgcatgaaa acgatagtgt cttttcatac taaagatgag
    15241 aataacatat cttctgaact gttgtcaatt ccattttcca tattttgcac tagagcgtgt
    15301 ctgaaaaagg ctttctgcaa gatgtgcgtc acaatttgtg ggatattttg cccggatgag
    15361 ggcgccgtag cgggctacgg caactgaatt cgggtgaaat atcccgcaaa gtgggggcgt
    15421 gcagattgcg ggaatgattt ttcagacacg ctctagcttt acccgctttt tatattttct
    15481 tcatttatca gggaaaactg tgtttatttt ttaacaattt ctttccttga gaaaacgtat
    15541 tttatttcat gaccagggat tacgattctc ttctcttatc aatttgcaca acttttatcc
    15601 agtttactca cattttttga cgtttcaaca aaaatttctt gacatttttt tctcaaaatg
    15661 atatattgta ttcatcaatt gaaagaacct tcgagtactg acggaaagag tggagtgcaa
    15721 accacgtgga gtcggaggtt tgtgggagcc gaccgtctgg gcagtatttg aaatattcag
    15781 atactggcct ttttttataa ctttcagggc agaaatcagg aataccaggc agaccggcca
    15841 atacttcttt caattaataa ttgttgctga tcgcggagtg aacagcaaca gaagtttttc
    15901 atgttatgcg gaaacgaaag gagaaaaaca attatgggat tcaaatcaga cattgaaatt
    15961 gcacaggaat gcgagatgct tccaattact cagatcgcag agaaagcagg tattgacgac
    16021 aaatacctgg agcagtacgg aaaatacaaa gcaaaaatcg actacaatct tctgaaagaa
    16081 agtgataaga aggatggaaa attaatcctc gttacagcta tcaacccaac tccagcagga
    16141 gaaggtaaaa ctactactac tgtaggtctt gcagatggta tgcagagact tggcaagagt
    16201 gttatggtag ctcttcgtga gccatcctta ggaccggtat tcggtgtaaa aggtggtgca
    16261 gcaggcggcg gatatgcaca ggttgttcct atggaagata ttaaccttca cttcacaggt
    16321 gacttccatg ccattggcgc agctaacaac ttactggcag ctatgatcga taaccatatc
    16381 ttccagggca atgcattaaa catcgaccca cgtaagatca catggagaag atgtgtagat
    16441 atgaacgacc gtcagcttcg taacgtagta gatggtcttg gcggaaagac aaacggtatg
    16501 cctcgtgaag acggatacga catcacagtt gcatctgaaa tcatggcagt tctctgtctt
    16561 gcaagcgaca tcaaagacct gaaagaaaga ttatccaaga tcatcatcgg atatacatac
    16621 ggaaaagttt ccgagcagaa acctgtaaca gcaggtgacc ttcacgcaga aggcgctatg
    16681 acagccctgt taaaagatgc tctgaaacca aaccttgtac agactctgga acacgttcct
    16741 gcaatcgtac atggcggacc attcgcaaac atcgctcatg gatgtaactc tgtaacagct
    16801 acaaagatgg ctatgaagct tgctgattat gcaatcacag aagctggttt cggtgctgac
    16861 cttggtgctg agaaattcct tgatatcaaa tgccgtatgg ctggtttaaa accaagcgca
    16921 gttgtaatcg tagctacagt acgtgccctg aaatacaacg gcggcgttgc taaagctgac
    16981 cttaacaatg aaaacctgga agctcttgaa aaaggtatcc cgaacctgtt aaaacacgtt
    17041 tccaacatta aaaacgtata caaacttcca tgtgttgttg ctatcaacgc attccctaca
    17101 gatacaaaag cagagcttga ctttgtagaa gctaaatgta aagaactggg cgttaacgtt
    17161 gctctttctg aagtatgggc aaaaggcggc gaaggcggaa tcaaacttgc agaagaagtt
    17221 atccgtcttg ttgaagaacc aaacgacttc tcctatgcat atgaactgga aggttctatc
    17281 gaagacaaac tgaaccagat cgttcagaaa gtatatggcg gtaagagagt agttctgaca
    17341 gctaacgctc agaaacaggc gaaacagtta gaagctcttg gattcggcaa ctgcccgatc
    17401 tgtgtagcta agactcagta cagcttaaca gatgaccaga ccaaactggg tgctcctact
    17461 gacttcgaag ttacagtacg taacctgaag atttccgctg gtgcaggatt catcgtagct
    17521 cttacaggcg agatcatgac aatgccaggt cttcctaaag ttccggctgc tgagagaatc
    17581 gacgtagacg agacaggtaa gatcacaggt ctgttctaat ccggttgaaa tcaatcgaat
    17641 aattcaaaaa tataaaaatc atatttatgt atgatatgtg tccagacgat ttaacaggcg
    17701 ggaagatttt cccgcctgtt tttttcttta tttttttata agataatctt ttccggaaat
    17761 accaggttcc gtcatatgga tcggatccag aatgcgatta agttcatcat cgtccataag
    17821 cttttctttc agaatcagac gtcttacaga ttcgcctgtc ttaattgcct tttttgcaat
    17881 atccgcagcc ttctgatatc caagatgggg gctgattgca gtgataatac ctacactgtt
    17941 ttctaccaga taacggcatc tttcttcatt tgccgtaatt cctacaatac aattatctac
    18001 caatgtctgg actgcatagc caagagtatc gatagactga aacatgcaat agaaaataat
    18061 cggctcaaag gcatttaatt ccagctgacc agcctctgca gccatagtaa tcgtaacatc
    18121 attaccaata atattaaaag ccacctgatt cactacttca ggaataaccg gattaacttt
    18181 acctggcata atagaggaac cattctgttt tgccggaaga ttaatctccc caaaaccagt
    18241 acgtggaccg gaggacatca gacggagatc atttgacatt ttggaaagag ttaccgcaca
    18301 tgctttcaca gcaccggaaa cggctacaaa tggatccaga ttctgagtgg aatcaatcag
    18361 atcaaaagcc tgtataaagt ccattcccga tatttcagtg agatttggaa caattcttct
    18421 cagatagccc tcatctgcat taattcctgt tccgatagca gtacctccca tattaagagt
    18481 ccgcatttca tccattgctt tatccattct gtggatatca cgcatgattg ctaccgaata
    18541 tgccttaaat tcctgtccca gacgaattgg tactgcatcc tgcatctgtg tacgccccat
    18601 ttttattatg tgatcaaact ctgtagcttt ttcattaaga gcatcataga ggcgaagaag
    18661 ctgttttttc agattctgca acaaacgaag agaagtcatt ttaccggcag taggaataac
    18721 gtcattggta gactgtccac aattcacatc atcgttagga tttataattg tataatcgcc
    18781 cttttttcct cccagtatct caatcgcgcg atttgcaatt acttcattgg cattcatatt
    18841 taaagatgtg ccagctcctc cctgaacagg atccacaata aattcattat ggaattttcc
    18901 tgaaacaatt tcatcacatg cctggacaat cgcctgtgct tttttcttct caagaagccc
    18961 cacctcacaa ttggttatcg ctgctgcttt ttttatgtat gcaagactgt taataatttc
    19021 cggatgcata ttcagccccg taatgtggaa attttcagcc gcacgtaagg attgtactcc
    19081 ataatataca tcttccggaa tatcctttac accaatagaa tccctttcta cacgatagtc
    19141 tgtttttttc atagttattc gccctcccat gtatttgccc tcattatata tctctgctat
    19201 aatataatca aatacatata tttttataaa atatatagtg tttaaattat atatcggagg
    19261 agtttatatg tttcagggaa tggaatacat ctatgaggtc tacaaggaaa aaagcttttc
    19321 caaagctgct gctgctcttt tcatttcgca gccttcttta agcgccaatg taaaacgtgt
    19381 ggaaaaccgt attggctatc ctatttttga tcgaagtacc aaacctttgc agttaactga
    19441 agttggaaaa cattatatac aggctgttga aaaagtcatg gatattgaaa ataatctcga
    19501 aaactaccta ctggatctgg gaaatctcaa aacaggaact cttaatgtag gtggcagtaa
    19561 ctttttttct tcgtggattc tgcctcccct tattgctgat ttttcccaaa aattccccca
    19621 tgttcaaatt tctcttgtag aagaaagtac agcaaaacta tcccagtttc tccaggccgg
    19681 aaagttagat ctggtgattg ataactgtat tctggataac cagatttttg aacgttatat
    19741 ctaccagaaa gaacaacttc ttcttgcagt tcccaaaaat tattcagtaa ataccagact
    19801 gcagaaatat cagattccta ttgaggaaat ccggaacggg cagttccgtt cttctcatat
    19861 tccttctgtt ccattaaaca aattcgagaa cgaaccattt attattcttc gttcagataa
    19921 tgataccggt aagcgtgcac ttaccatttg tcaggaaaat cacttttcgc cttctgtagt
    19981 atttcgccta gatcagcaga tgactgccta taatattgca tgtttgggaa tgggtatcac
    20041 tttcatcggg gatcttctgc tctccagagt tccaacaaat tcagaacttg ttttttataa
    20101 gctgcccggt cagagcagta aacgcactgt gtttttttac tggaagaaag gccgctatat
    20161 cagcagagcc atggaagaat tcctgaagct gcccttttcc tgatatgtca taatcaaata
    20221 ggctgtggtg attggtcatc atcagatgta cgtcaaaatg gggttgttgt gctaaataag
    20281 cacaacaacc ccagtatgtc aggcagatat tcgattagaa caatggcttc atcgccggat
    20341 acagagttct gaacttctga tatctctctt catattttgc aaccagttca ggatccggtt
    20401 ctaccgtatc aacaactttg gcaaatttct taccgatggt ttctacatcc gggtaagcac
    20461 cacagcctac tgctgccagc atagctccac ccatggacgg tccttcttcg ttctccagaa
    20521 catcaacctt caggttcata acgtttgcaa tgatcttctt ccacagtggg ctcttagctc
    20581 caccaccgca gatcttggtt ctctcaatct tgattccaag gtttcttgca acttccaggg
    20641 aatcacgaag accaaaggca acaccttcca gaacagcctg tgtcatgtct gctcttgtgc
    20701 tgtccatgga cattccgaag aatacacctc ttgcatcagg attattatga ggtgaacgtt
    20761 ctcccatcag atatggaagg aagaatacat gattctctcc cagcttctga attggagcct
    20821 gctctgctgc gaaatccttt gtctgaagaa tctcctctgc ccaccatttg ttacaggaag
    20881 ctgcgctgag catgcatccc atcagatgat agcttccatc tgcatgacag aaagaatgaa
    20941 gtgcgttatt ttcgtccaca ccaaagtttt tactggaaat aaacacagtt ccggatgttc
    21001 caagagaaat attacactga ccgtcaccaa ctgtacctgt tcctacagca gctgccgcat
    21061 tgtcacctgc acctgcaaca acttttacat tctcactgaa tccaagttct ttcgcaatct
    21121 caggtttcag agttcctact acttcccaac tctcatacag tttcggaagc tgctcttctg
    21181 tgattccaca gatctccagc atttcttttg accagcagcg gttcttcaca tcaagaagaa
    21241 gcataccgga agcatcagaa acatctgtac aaaaagaacc ggacagacga tatgccagat
    21301 aatccttagg aagcataatc tttactacct tcttaaagtt ctcaggctca tttttctgca
    21361 tccagaggat cttcggtgct gtgaagcctg cgaaagcaat atttgctgta tactgtgaaa
    21421 gtttgtcttt tccgatcact gtattcagat attctgtctc ttcgcctgta cgtccgtcat
    21481 tccagaggat tgcaggacgg atcacattat catccttgtc aagtgttacc agaccatgca
    21541 tctggccgcc aaaaccaatt cctgctacct gcgctctgtc gatatccttt gtcagctctt
    21601 tcatgccttc catactctgc gcaaaccagt cttccggttt ctgctcagac cagcccggat
    21661 gtgggaagaa taaaggatat tctctggata cgatgttaca gatttttcct gattcttcca
    21721 taagaagaag ttttacagcg gaagtaccaa ggtcaatacc aatataatac ataagtgctc
    21781 tccttttcta tttctaatct aatacatccc agagcaaagc cccgggatgc ctttaatata
    21841 gtgtcagttt atttattctg tattcagatt cattcacttc acatgaacat taataatccg
    21901 ttttactgat ttctcattaa ccccatggat tttctgtcgg gtatcttacg cctgccggct
    21961 ggttatatcc aatcttctta acatccagtc caaggaattt cactacctca tagaatgctt
    22021 ttccgtaatg tccaaacata actgctccat gatgcggata gttgccctcg atcagtacgt
    22081 gacggtagaa tcttcccatt tctttgattg cgaaaatacc gataccaccg aatgatcttg
    22141 taggtacatc cagtacttca ccttctgcaa cataagaaac cagctcgccc tcggaattgc
    22201 actgtaaacg atagaatgta atgtcagatg cagcgatatc accttcaaga gttcctcttg
    22261 tgaagtctgg ttcagatcct gccggctcaa gaagtctgtg ctggatcagc tgatatttaa
    22321 cagctctgga atcacacatc ttgcatgcag gagtatttcc acaatggaat cccataaatg
    22381 tatcagtaag cttataatcg tattttcctt taatatcttc atcatagata tactgtggaa
    22441 cagagttgtt gatatcaagc agtgtaactg catcattgga aatgcaaagt ccgatgtact
    22501 cgctgagtgc tccgtagata tcaacctcac aggataccgg aattcctctg gaaaccagac
    22561 ggctatttac atagcaaggt tcaaatccaa actgtgacgg gaatgcaggc caacatttgt
    22621 cagcaaatgc aacgtatttt cttgctccct tatgagcctc tgcccagtca agaagtgtaa
    22681 gctcaaactg tgccattttc acattaaggt cagcataata tttgccttcg cccatctctt
    22741 ttgccatatc tgcacaaact tccgggatac gaggatcatt ttcatgctct ttgaaagaaa
    22801 caagaagatc aagctctgag ttctcttcaa tctcaacacc cagctcatag aggcctttaa
    22861 taggtgcgtt gcatgcgaag aagtcctgtg gacgtggtcc gaaagtaatg atcttaagat
    22921 tgctgacacc gatgactgca cgtgcaaccg gtacgaaatc agcgatcatc tttgcaatat
    22981 catctgctgt tccaacagga tattccggaa tatatgcttt cagatgacgc atttttaagt
    23041 tgtaggagca gttaagcata ccacagtaag catcacctct gccgttgatc atatcaccgt
    23101 caccttctgc tgctgctaca tacatacaag gtccgtcaaa tctctctgcg atcagagttt
    23161 caggagtttc aggtccgaag tttccaagga aaacaaccag cgcattacac tctgctttgt
    23221 ttacatcttc aagagctttc tccatatcc
//
