LOCUS       c00094_gnlPro..        15492 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FKHCHIMF_136.
ACCESSION   c00094_gnlPro..
VERSION     c00094_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:24:30
            Original ID  :: gnl|Prokka|FKHCHIMF_136
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1977
            Orig. end    :: 17469
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15492
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[11977:14229]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12252
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15492
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15492
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1011..1244
                     /locus_tag="ctg94_6"
                     /transl_table=11
                     /translation="VGKELFETLPDVLDAKMLASALSISKAGAYQLLNLPDFPTLQVGG
                     RKLVTKQKLALWMEQHTNTAGQAGAGKENKSR"
     CDS             1241..1531
                     /locus_tag="ctg94_7"
                     /transl_table=11
                     /translation="MKLTKYEQETIINFNNDEQEASIYTASPQMMRKLDALAAAYPEHY
                     RVVEQTEVSKTYSCEKHLINLRKPRKQNEEHSQWARQRMQEMNRHKNAGNL"
     CDS             1718..2125
                     /locus_tag="ctg94_8"
                     /transl_table=11
                     /translation="MIKNRNETSAAMDKALKNLEQAKARYEAERKKENEKRRKAQNHHK
                     YLMGGIVAKYFPECYQYEEKELNVILSAALASAECRQAVENVKRMENNADEMEDEKDRN
                     GGHADETKTKENSGGYANSKDFAGGSFSQGV"
     CDS             2409..4106
                     /locus_tag="ctg94_9"
                     /transl_table=11
                     /translation="MRTKYASTRFGIVKRSKGQSAVDAASYISRSVLVSEYDGKTYRPK
                     YHEDLVHCEINLPEYAPEEWLDRAVLWNSVELNEKQKNAQLCRTLKAALPNDWSYELAE
                     ETVRDYVQRNFVSKGMCADWAIHDSVNQNGIHNLHFHLMLTLRPVEENGKWGAKQRKEY
                     ILDKDGNKIRNKSGRGFKSRAVDVNDWNEKGNSRKWRKDLTDTINVVNDRIGLPEYWEH
                     RSFKELGLEQEPTRHLGPIASALERKGIRTEKGDANRAIMEHNQTLQRARMFYDIAWNS
                     VKNLEKWEQEKAAEAAKNAAEKKAGKMAGDIPAAQEGEAEQTAVGSIQKETSGTKEVSV
                     FAAMKNEVLEMLERILAAFGRLHLPLIQAPNFKKVSNRAALMDIENVRRFVEEKGIDSF
                     EALETFAVQQEASKKEAEEICNRDGREIRRLKELSEAYAAYAPYIPIRNEYLQKKGIAQ
                     AVYHSQHKKELETAKELRIPVYELLREGEKFTPKKWEAQIKELTQEYEKQSRRYGRSTV
                     NLAYVELLRHNRKMDERDQKNKDQSQSRQHEKMDRGQKQKKKHQEMEL"
     CDS             4169..4438
                     /locus_tag="ctg94_10"
                     /transl_table=11
                     /translation="MSKDCRTTKNRNNSLTVGVLAGIILCQHWYLWRDFMQRKAGNRRR
                     EPIRYVVEHVYSGKESMEKVLTAVSEEAAKQNVKEKLENQKKVG"
     CDS             4435..4620
                     /locus_tag="ctg94_11"
                     /transl_table=11
                     /translation="MRKDADFTGKIKSAVAGGGRNRYNKDSVFLSLDIEETTGGQYADN
                     RNQRNMDSTLCKIIIG"
     CDS             4559..6184
                     /locus_tag="ctg94_12"
                     /transl_table=11
                     /translation="MQTTEIRETWTALYARLSLDDGNVGESMSIQSQKAILTRKAEELG
                     IYNYRFYVDDGYSGTNFNRPSFQQMIADIEAGKVTCVITKDLSRLGRNYLESGAYIEVF
                     FPKHQVRYIAVNDGVDSANSGEMDITPFKNILNEFYSRDVSKKVKSGKYIRASQGKFMG
                     THAPFGYQKDPEDKNHLIADEETAPTVRYIFQLALQGMGNNKIGKILYEQKIPKPAYYK
                     PEYFGKFLVKEDDAYNWKQETVIRILRNPLYKGYFWVQKYDKKHFKQETRGYIPMSERT
                     IIPSDHEALVDEHTWDTVQEILDRHTKVKPCTSGYENKFRGILKCADCGSTLMVHTDGR
                     NKEKPVIERTFYQCRIYRVRGTGFCSQHRINADDLEKLVLADIQTHAKKVIKNREKFMR
                     KVLGQMDTTAANNRENIQKKLEKLEKKLLESDRQFIKLYEDFTKQLVSEQQFRMLSTHF
                     EQEKKETTEEIEKLKTTADNLKDSTCKAEQLANEMVECAEIKELTTAIVNRLIEKIEVS
                     EPQTIDREKVQNIRIFYKFVGEIN"
     CDS             6333..8030
                     /locus_tag="ctg94_13"
                     /transl_table=11
                     /translation="MLNLPVPEAEYENVVLKPSEYQKDMVASLAERAEAVRDRQVQPYE
                     DNMLKITNDGRKLALDQRLINDMLPDDENSKASTCVEKAFEIWEQTKEQKSTQLIFCDL
                     STPKGDGTFNVYEDIRNKLIEKGVPPEEIAFMHEANTELRKAELFGKVRSGQVRFLLGS
                     TQKMGAGTNVQDRLIALHHLDVPWRPSDIEQQEGRILRQGNLNPKVKIFRYVTEGTFDS
                     YSWQLIENKQKFIGQIMTSKSPVRSCEDVDEAALTYAEVKALATGNPYIKEKMDLDIQV
                     SKLKLMKANHTSQKYRLEDNIAKHYPQQITILKECISGMQADIQTAKANLPVDKEQFSM
                     KEGDKLYTDKKEAGTALVEMCKEIKTVNAPAVIGEYAGFKMAVSFDAFNQKFVMNLKGQ
                     LSHNLEVGSDPIGNIARINHALESMPKQLMEAQTKLETVEHQLETARVEVTKPFAQEAE
                     LAEKLERLSALNALLNMDEKGNDGIDMDDEPEAPKSEKEVADRPAKNTPLAEKTMGIGQ
                     DKSIRQYADVPAERVSLKAKLEVMKAKVAGGDTEKPMPQKVKGKEETL"
     CDS             8128..9507
                     /locus_tag="ctg94_14"
                     /transl_table=11
                     /translation="MDIKQIVLDLCALSDEQEWFEFKENWFQPEALGEYVSALSNAAAF
                     HYKKYAYFIWGVNDTTHEIVGTTFNQYCEYNKEPYQNYLARNLSPSINFSFEETEIYGK
                     RVVGLVIPAATEIPTAFKEKRFLRIGSSKCNMKDYPKREIELFKILDGRTETIETVPAK
                     YQELTFQKLFGYYGSKGIVLNQKTFIKNLGLKTEEGEFNILAQLLSDNSHFPLRVSIFD
                     GETKGSNLFSVREFGNDCLLYSLDELLRYGDVLNLIQADETDRVVERKEVPLFDNKAFR
                     EAVINAVLHNKWVEGNEPMISVFSDRIEILSRGTLAPAQTMEGFFLGESIPVNEKLSEI
                     FLQLHISEKSGRGVPKITEMYGKDAFSFRENSIVVTIPFERINKVGNKVGKKVGDKKSL
                     NSRRQKIISEMRDNPNITTAELHNILGVSETAVENNISFLRENGYIERVGSKKAGYWKV
                     L"
     CDS             9581..9901
                     /locus_tag="ctg94_15"
                     /transl_table=11
                     /translation="MDWCWHSCCAYGDWCHPDSSEFTDSEAIRKNVSETERHILGETSQ
                     WDGNTDSAVIPYWLVWKGAEWDIYFVPFYNGKDGNSAFVRSGNLCSYFYQYTPIARITG
                     NH"
     CDS             10001..11545
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 270.5; E-value:
                     9.3e-83)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg94_16"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.3e-83, bitscore:
                     270.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.8e-17,
                     bitscore: 52.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTIIIIGAGLAGLSAALQAAENGCNVKLVSSLPSERAQSVMAE
                     GGINAALNTKDENDSPEEHFTDTIKAACGLADPNAVWGMTQAAPELVHWLLKLGVKFNM
                     SGYDDVDLRNFGGQKKKRTAFAQSDTGKQIMTAMIDAVRRKEASGMVERFSHHSFLTLR
                     LCGNICCGCVIRDEYSQETVELPGDAVIVATGGMHGLFGNTTGSLSNTGEVTAELFRLG
                     VPLANSEMIQYHPTTVKCGGKRMLISEAARGEGGRLFAMKDGKQWYFMEEKYPELGNLM
                     PRDITAREIWKVSHESEVFLDMTEISEEIISNKLSGLADDCMTYLHKDIRKEPVSVLPG
                     IHYFMGGILVDEQHRTPIQNLYAAGECCAQYHGANRLGGNSLLGALYGGRVAAKSAREQ
                     ADVVDLSCATQIDFPPTSQISEIKQLNKVMQDTMGVVRNENTLLNGIQTVQALTGNLPL
                     LGMAVLKSALARKESRGAHWREDYPKSNDDDYLKTTVARFDGKQIQISFVPVPERR"
     CDS             11551..12252
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 91.5; E-value: 1.1e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg94_17"
                     /sec_met_domain="Fer2_3 (E-value: 4e-29, bitscore: 91.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00092, bitscore: 10.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVYKIRIRRQESQKSDSYWQEFEFDGSKNSSVANVLKELNSRTPL
                     KDNSGNIVTPISWECSCMVRKCGACAMLINERPRLACSTFLHTLKGSTITLEPLSKFPL
                     VRDLIVDRSILFENLKKLNLWLESEAYMNRWTHEPRYQSARCLMCGCCLEVCPNFSANG
                     TFAGAVAAVNAFRILNEEQESTHLNEISAEYKKKYFEGCGKSLSCHDICPIGLPLEELL
                     VRSNAAAVWGK"
     CDS             12277..13020
                     /locus_tag="ctg94_18"
                     /transl_table=11
                     /translation="MYEENQKLKTWITPDLATEYLAGAVLLGAAPCTAMVFVWSTLTKG
                     NPAYTVVQVASNDIIILFAFVPIVKFLLGVSNVSVPFQTLFMSVVLFVVIPLVAGIITR
                     LLVVRKKGTEYFEQTFLHKFDSATTVGLLLTLILIFMFQGEVVLDNPLHIILIAVPLII
                     QTFFIFSLAFGVCRIIRLPYDIAAPAGMIGASNFFELAVAVAVALFGTSSPAALATTVG
                     VLTEVPVMLTLVKIANKLKEKFKYE"
     CDS             13013..13426
                     /locus_tag="ctg94_19"
                     /transl_table=11
                     /translation="MNKKKVAFICVHNSCRSQIAEALGKHLASDVFESYSAGTETKLQI
                     NQDAVRIMKELYGIDMEAEGQYSKLIDEIPVPDIAISMGCNVGCPFIERPFDDNWGLED
                     PTGKSDEEFKKVIDEIRMQIFILKQRLDEFEEN"
     CDS             13736..13972
                     /locus_tag="ctg94_20"
                     /transl_table=11
                     /translation="MRTIYAEYNINHDSIDVYTSAGYMLRIDCWEAEKDLKTTYGSECA
                     LTSLAVDEPLEYARLYLNGNLQMWVDAEDSLEL"
     CDS             complement(14238..15155)
                     /locus_tag="ctg94_21"
                     /transl_table=11
                     /translation="MSVVLQIYAIIVTLSLIIVLSFYLFHRREVTRLSQKLQTLLHSFT
                     HAELTLDFPSSDITDLVNALNELLRVYHKQVYSLQKKDEAIKETITNLAHDLRTPVTAI
                     QGYTQMLLQSPELSEEDLDAAVIINERLNVLNQLLNQLFEFARIEADEMDFSYTTFDLN
                     AVLRSVAVSFFKSFEERKIIPVLSIAEISFPFYGDEKAVTRIFENIISNALSHGKSDYH
                     FSSYDDNENYHFSFQNFTDSINESDIDKIFNRFYTTDLSRSRKTTGLGLTIAKNLTVKM
                     GGSISASLNNNVFEIVVCFPKQKG"
     CDS             complement(15175..15492)
                     /locus_tag="ctg94_22"
                     /transl_table=11
                     /translation="KSYEERMLEMEKKEQESLVFLIRNSSVSMAVNALLIFFGYLVLHG
                     LESILGLGYNITIFWAISNINKTRIDMAVQWLPTAIIIFFAYMIIFGGVIGTIFKKRDI
                     T"
ORIGIN
        1 aagcagaatg acaatggaga aatcattgaa atgaagcagg gacaggtgat aaaaattcca
       61 aagaacagcg gcaaagcatg gctgacatta ttttatagtc tgccgcagga gtttgtcagc
      121 aaacgtcctg tttatctgaa cttcccacgc tgcccttatg aggtgctgcg gacggataaa
      181 tatgacagta tgataaacaa tgatacattt ctggaactgg tatgggattg tgtggcatgg
      241 agcgcatggc agtattttga agttccatat caaaaaggcg gctaccggga gatacccggc
      301 agtgcggcgc agtattccgg ggactttccg ttgtggcggc tctcttactc tatgcttccg
      361 ctcctgcgtg acaaatttga ggtcagcgga ttttctttcc agcagcttta caacgtgccg
      421 gagggaacgg aacttccgtg gcttacttat cagcagtttg gcaatctgat cggtaccctt
      481 gtacctgaaa ttatacaaga acagaactgg cagccgatga ttgatgaaat ctggaacaac
      541 cgaacccttg aggacttcga taaaagagga agtcaggtaa agctggactt catgcgttcg
      601 tggggacaca gccgttccag aaaaaagacg gtatccatag agcagcttgc agaggaagca
      661 gaagaaaatg gcacagactt tgatattccg gatacgagga gtgagtttga aaactcggtg
      721 ctgtcagaac ttcagattgc ggagtttgcc gctaggcttt ccgggcgtga taagaagatt
      781 ttgaaaatga aaatggaggg gcatacggca caggagattg cggaagctgt aggctatcag
      841 acacacagtg cggtgctgaa aagaatccgt catattgcag actgttatga ggattttatc
      901 tcagaagaat atcagaaata tctggaaaca ttctaatcca tccatcccat cggcagctat
      961 cctatgatag ctgctttctt ttacccattt ctaaacaggg ggtgattttt gtggggaaag
     1021 aattatttga aacgctgccg gacgtgctgg atgcaaaaat gctggcatcg gcgctttcca
     1081 tttcaaaggc aggagcatac cagctattga accttccgga ttttccaacc ttgcaggtgg
     1141 gaggacggaa acttgtcaca aagcagaagc tggctttgtg gatggaacag catacaaata
     1201 cagcaggaca ggcgggagcc ggaaaggaga ataaaagtag atgaaattga caaagtatga
     1261 gcaggaaacg attatcaatt ttaataacga tgaacaggaa gccagtattt atacagccag
     1321 cccgcagatg atgcggaaac tggatgcact ggcggcagct tatccggagc attaccgggt
     1381 ggtagagcag accgaagtga gcaagaccta ttcctgtgaa aaacacctca tcaaccttcg
     1441 gaaaccgaga aagcagaatg aggaacacag ccaatgggca aggcagagga tgcaggaaat
     1501 gaaccgccat aaaaatgcgg gaaatttatg aaagaaccgc acacagaggt gacagctctg
     1561 tgtcaggaag aaagctgtcc gtgaaaatac ggaaattaag aaaaatagaa aaccaaatgg
     1621 caggagagcg gctatggaca tggaaaaggt tcaggctgtt tttttatgcc ataaaataaa
     1681 aaatcaaaca gaaaaatgag aaaaggagta taaacacatg ataaaaaaca ggaatgaaac
     1741 cagtgctgca atggataagg cactgaaaaa tctggaacag gcaaaggcaa gatatgaggc
     1801 agagcgcaaa aaggagaatg agaaacgcag gaaagcacag aaccatcata aatatctgat
     1861 gggcggcatt gttgcaaagt atttcccgga atgttatcag tatgaagaaa aagaactgaa
     1921 tgtaatcttg tcagcggctc ttgcttcggc agagtgcagg caggcggtgg aaaacgtaaa
     1981 aaggatggag aataatgcgg atgagatgga agatgaaaaa gacagaaacg gcggtcacgc
     2041 cgatgaaacg aagacaaaag aaaacagcgg cggatacgcc aattcaaaag attttgcggg
     2101 tggcagtttt tcgcagggag tgtaagcagt atctccggga gtatgggttc accccagtta
     2161 tggggtgcgc acagatagac cacactccgt atggtcttgt gcgctctccg agggcacctg
     2221 cggtgggcgt tgcctgcctt gcaccagtca agaggggaaa taacctttcc cctccgtccg
     2281 ctgcgcttcc tacccctttg tatcctttgc atctgcccgt aacccggaaa acacacccgg
     2341 ctttcgtcca tctgcaaagg cttttcttgc tgccctctat tttacggtaa gggaggaact
     2401 ttgtgagtat gcgcacgaaa tatgccagca caaggttcgg cattgtaaag cggagcaaag
     2461 ggcagtcggc ggtagatgca gcttcttaca tcagcaggag tgttcttgtc agcgagtatg
     2521 acgggaaaac gtatcgcccg aaataccatg aagatttggt gcattgtgaa atcaatctcc
     2581 cggaatatgc accggaggaa tggctggaca gggcagtgct gtggaactct gtggagctga
     2641 atgagaaaca gaaaaatgcc cagctttgcc ggacactgaa agcagcactt ccaaatgact
     2701 ggagctatga gctggcagaa gaaacggtgc gggattatgt gcagcggaat tttgtttcca
     2761 aagggatgtg tgcggactgg gcaatccatg attctgttaa tcaaaatggc atccataacc
     2821 tgcatttcca tcttatgctc accctgcgcc cggtggaaga aaacgggaag tggggagcca
     2881 agcagagaaa ggaatatatc cttgataaag acggcaataa aatccgcaat aagtccggac
     2941 ggggatttaa gagcagggcg gtagatgtga atgactggaa tgaaaaaggt aattcccgga
     3001 aatggagaaa ggatttgacg gacaccatca atgtggtgaa tgaccggatc ggactgccgg
     3061 agtactggga acaccgttct tttaaagagc tgggactgga gcaggagccg accaggcact
     3121 taggtccgat tgccagtgca ttggagagga aaggcatccg taccgaaaaa ggggatgcga
     3181 accgggcaat catggagcat aaccagacgc tgcaaagggc aaggatgttc tatgatattg
     3241 catggaacag tgtgaaaaat ttggagaaat gggaacagga aaaagctgcg gaagctgcaa
     3301 agaatgccgc agaaaagaaa gcaggaaaaa tggcaggaga catccctgcg gcacaggaag
     3361 gtgaagcaga acagacggca gttggttcga tacagaaaga aacttccggt acaaaggaag
     3421 tcagcgtatt tgcagcgatg aaaaatgagg ttctggaaat gctggaacgt attcttgcag
     3481 catttggaag gcttcatctg ccgctgatac aggcaccgaa ttttaaaaag gtaagtaatc
     3541 gtgcagcact gatggatatt gaaaacgtgc ggaggttcgt ggaagaaaaa ggcattgaca
     3601 gctttgaagc actggaaacc tttgcagtac agcaagaagc ttccaagaaa gaagcagagg
     3661 aaatctgcaa cagagatgga agggaaatcc ggcggttaaa ggaactgtca gaggcttatg
     3721 ccgcctatgc tccatacatt cccatccgta atgaatatct gcagaagaaa ggaatcgcac
     3781 aggcagttta tcacagccag cataagaaag aactggaaac ggcgaaagaa ctccgtattc
     3841 cggtctatga acttcttcgg gaaggagaaa aattcacacc gaaaaagtgg gaagcacaga
     3901 tcaaagagct gacacaggaa tacgagaaac agtccagacg ttacggcagg agtaccgtta
     3961 atcttgccta tgtggagctg cttcgtcata accggaagat ggatgagcgg gatcagaaga
     4021 acaaagacca gtcccagagc cgacagcatg aaaaaatgga cagggggcag aagcaaaaga
     4081 agaaacatca ggaaatggaa ctttagattt atacatcgtt aaggaaaatc tgccgggatg
     4141 ttccccggca ggcagaaagg agattgcaat gagtaaagat tgcaggacta cgaaaaacag
     4201 aaacaatagt ttgacagttg gtgtgctggc agggataatc ctctgccagc attggtattt
     4261 atggagggat tttatgcaga gaaaagcagg gaaccgccgg agagaaccca tccgctatgt
     4321 ggtggaacac gtttattccg gcaaggagag catggaaaag gtactgactg ccgttagtga
     4381 agaagcggcg aaacagaatg taaaggagaa actggaaaat cagaaaaagg tgggatgaga
     4441 aaagatgcag atttcaccgg aaaaataaaa tcagcagttg caggaggtgg caggaatcgc
     4501 tataataaag acagcgtatt tctgtcactg gatattgaag aaaccacagg aggtcaatat
     4561 gcagacaaca gaaatcagag aaacatggac agcactttat gcaagattat cattggatga
     4621 cggcaatgtg ggcgagagca tgagcatcca gagccagaag gcgatcctta caagaaaagc
     4681 agaagaactg ggaatttata attatcggtt ttatgtagat gatggttatt ccggtacgaa
     4741 tttcaaccgt ccgtcctttc aacagatgat agcggacatc gaagcaggaa aagttacctg
     4801 tgtgatcacg aaagatcttt caaggctagg caggaactat ctggagagtg gcgcttatat
     4861 tgaggtattt ttcccaaaac atcaggtacg gtatatcgcc gtcaatgacg gtgtggattc
     4921 cgcaaacagt ggggagatgg atattacccc gtttaagaac attcttaatg agttttattc
     4981 aagggatgtt tctaaaaagg tgaagtcagg taagtacatc cgggcaagcc agggaaaatt
     5041 catgggaaca cacgcaccat tcgggtatca gaaagacccg gaggataaaa accacctgat
     5101 tgctgatgaa gaaaccgcac caaccgtccg ttatattttc cagcttgcac ttcagggaat
     5161 gggaaacaat aaaatcggga aaatccttta tgaacagaaa atcccaaagc cggcatatta
     5221 taaaccggaa tattttggaa agtttctggt aaaagaagat gatgcctata actggaaaca
     5281 ggaaaccgtt atccggattt tacgcaaccc gctttacaaa ggctatttct gggtgcagaa
     5341 atatgataag aagcatttca agcaggaaac aaggggttat atccccatga gtgagcgaac
     5401 cattattccc agtgaccatg aggcacttgt cgatgaacac acatgggata cggtgcagga
     5461 aatccttgac cgccatacga aagtcaagcc ctgtacttcc gggtatgaga ataagttccg
     5521 gggcatttta aaatgtgccg actgcggaag taccctgatg gtgcataccg atggcaggaa
     5581 taaagagaag ccagtcatcg aacggacttt ttatcagtgc cgcatctacc gtgtgagggg
     5641 aaccgggttc tgcagccagc accgcatcaa tgcggacgat ctggagaaac ttgtacttgc
     5701 ggacatccag acccatgcaa aaaaggtcat aaaaaaccgg gagaaattca tgcggaaggt
     5761 attggggcag atggatacga cagcggcgaa taaccgggaa aatatccaga aaaagctgga
     5821 gaaactggag aaaaagctcc tcgaatcgga cagacagttc atcaagctgt atgaggattt
     5881 tacaaagcag cttgtgtcag aacagcagtt ccggatgttg tccactcatt ttgaacagga
     5941 aaagaaagaa acaaccgaag aaattgaaaa actgaaaact acggctgaca atctgaagga
     6001 cagcacctgc aaagcggaac agcttgccaa tgaaatggtg gaatgtgcag agatcaaaga
     6061 gctgaccaca gccatagtaa atcgtcttat cgaaaagatt gaggtatctg aacctcagac
     6121 catcgacaga gagaaagtcc agaatatcag gattttctac aagttcgttg gagaaatcaa
     6181 ttaaatttcc ataatgtacc tataattcaa gagccattga gcttgcacca gagggaaccg
     6241 gatatcgggc aaagacaagg tttgcaaagt tttttaatct cccggagctg attgcacttt
     6301 ttaaggagag tgccgatatt cagacaccgg atatgttaaa tctccctgtg ccggaagcag
     6361 agtatgaaaa tgtggtgcta aagccaagtg aatatcagaa agacatggtg gcatctttgg
     6421 cagaaagggc agaagccgtg cgtgacagac aggtacagcc ttatgaggac aatatgctaa
     6481 agattaccaa tgacggaaga aagctggcat tagaccagag gcttatcaat gatatgctgc
     6541 cggatgatga aaattcaaag gcaagcactt gtgtggaaaa ggcatttgaa atatgggagc
     6601 agacaaagga gcagaaatca acgcagctta ttttctgtga cctgtcaaca ccgaaaggag
     6661 atggtacatt taatgtttat gaggacattc gcaacaagct gatagaaaag ggcgtcccac
     6721 cggaagaaat tgcatttatg catgaagcaa atacagagct taggaaggcg gagctgttcg
     6781 gaaaagtaag aagcggacag gtccgttttt tgcttggttc cacacagaag atgggagccg
     6841 gaaccaatgt gcaggacaga cttatcgcac tgcaccacct tgatgtgcct tggcgtcctt
     6901 ctgacattga acagcaggaa gggcgtattt tacgacaggg gaatcttaat cccaaggtca
     6961 agattttccg ctatgtgacg gaaggaacct ttgacagtta ttcgtggcag ctcattgaga
     7021 acaagcagaa attcatcggt cagattatga caagtaaatc tccggtacgt tcctgtgagg
     7081 atgtggatga agcggcactt acttatgcgg aggtcaaggc tctggcaacc ggcaatccct
     7141 acataaaaga aaagatggat ctcgatattc aggtatccaa gttaaagctc atgaaagcaa
     7201 accataccag tcagaaatac cgtctggagg acaacattgc aaagcattat ccccagcaga
     7261 ttacaatttt aaaggagtgt atcagcggga tgcaggcaga cattcagact gcgaaagcaa
     7321 atcttccggt ggacaaagag cagttttcca tgaaagaggg ggacaagctc tatacggaca
     7381 aaaaagaagc cggaacagcc cttgtggaga tgtgcaagga aataaaaaca gtcaatgccc
     7441 ctgcagtcat tggcgaatat gcaggtttta agatggcagt atcctttgat gcattcaacc
     7501 aaaaatttgt gatgaacctg aaaggtcagc tttcccacaa tctggaagtc ggttcagacc
     7561 cgattggaaa tattgcccgt atcaatcatg ccctggagtc catgccaaag cagcttatgg
     7621 aagcccagac aaaacttgaa actgtggagc atcagcttga aaccgcaagg gtggaagtaa
     7681 ccaagccttt tgcacaggaa gcggagcttg cggagaagtt agagcgtctg tcagcattaa
     7741 atgccctgct taacatggat gaaaagggta atgacgggat tgatatggat gatgagccgg
     7801 aagctccaaa gagcgaaaaa gaggtcgcag accgtccggc gaagaatact ccgcttgcag
     7861 agaaaacaat gggtataggg caggataaga gcatcagaca gtatgcagat gtacctgcag
     7921 aaagagtatc cctgaaggcg aagctggagg tgatgaaagc aaaggttgca ggaggagata
     7981 cagaaaagcc tatgccacaa aaggtaaagg gaaaagaaga aaccttataa gaaaatctga
     8041 agttttttta tttttattcc caactttatt cccaacatgt tataattatt ctggttggga
     8101 ataaaagttg ggtaaaggag catactaatg gatattaaac aaattgtttt agatttatgt
     8161 gccttaagtg atgaacagga atggtttgaa tttaaggaaa actggtttca gcctgaggca
     8221 ttaggcgaat atgtatctgc cctgtcaaat gcggcggctt ttcattataa aaaatatgcg
     8281 tatttcattt ggggtgtaaa tgatacaacc catgaaattg taggaacaac atttaatcag
     8341 tattgtgaat ataacaagga accgtatcag aattatcttg cgagaaatct gtcaccaagc
     8401 ataaatttta gttttgaaga aacagaaatt tatggaaaga gagtcgttgg tttggtaatt
     8461 cctgcggcaa ccgagattcc tacggcattt aaagaaaaga ggtttttaag gataggatca
     8521 tcaaaatgta atatgaaaga ttaccctaag agagaaattg aacttttcaa aatactggat
     8581 ggaagaaccg aaacgataga aacagtaccg gcaaaatacc aggaacttac atttcaaaaa
     8641 ctctttggat attacggttc caaaggtatt gttctaaatc aaaagacgtt tattaagaat
     8701 ctggggctaa aaacagaaga aggagagttt aatatattag cgcagcttct gtcggataat
     8761 tctcattttc cgcttcgtgt atctattttt gatggagaaa caaaaggctc taatcttttc
     8821 tctgtacgtg aatttggaaa tgactgttta ttatacagtt tggatgagtt gttgcgttat
     8881 ggagatgtat tgaacctgat tcaggcggat gagacagaca gggtcgttga acgaaaggag
     8941 gttccgttat ttgataacaa ggcatttcgt gaggctgtca ttaatgccgt cctgcacaat
     9001 aaatgggtgg aaggaaatga acctatgatt tcggtatttt ccgacagaat agagatacta
     9061 tcaaggggaa cacttgctcc ggcacagacc atggagggat ttttcttagg agaatcaatc
     9121 cctgtaaatg aaaaattatc cgagatattt cttcaactgc atataagtga gaaatctggt
     9181 cgaggagtcc ctaaaattac ggaaatgtat ggaaaagatg cattttcatt tagggagaat
     9241 tccattgttg ttactatccc atttgagaga ataaataagg ttgggaataa agttgggaaa
     9301 aaggttgggg ataagaaatc tttaaattcc agaaggcaaa aaattatttc agaaatgagg
     9361 gacaacccga acattacaac tgcagaactt cataatatat taggggtgag tgaaacagca
     9421 gtagaaaaca atatatcatt tttaagagaa aatgggtata tagagcgggt tggttcaaaa
     9481 aaggcaggat actggaaagt attgtaagtg ttgtaaaact ataaaacgaa gataaggtgt
     9541 aatcggataa caaaagaagt agtgcaggga aacttcttgc atggattggt gttggcattc
     9601 ttgttgtgca tacggtgatt ggtgtcatcc tgacagttca gagtttacag acagcgaagc
     9661 aatcaggaaa aatgtatctg aaacagaacg ccatattttg ggcgagacga gccagtggga
     9721 tggcaatact gattctgctg ttattccata ttggcttgtt tggaaaggtg cagaatggga
     9781 catatatttt gttccctttt acaacggtaa agatggtaac tcagcttttg ttcgtagcgg
     9841 caatctttgt tcatattttt atcaatatac gcccattgct cgtatcactg ggaatcatta
     9901 gttataaaga acgaaggagc gatatttatt tgatcctttc ggtgcttctt ctttttatag
     9961 cgggagcggt tattttatat tatattgggt ggcaatatct atgagtaaga caattattat
    10021 tataggtgct ggactggcag gactttcagc ggctttgcag gcagcggaaa atggatgcaa
    10081 tgtaaaactg gtttcctccc ttccgtcaga gcgggcacag tctgttatgg cggagggcgg
    10141 tatcaacgca gctttgaata caaaagatga aaacgacagt cccgaagaac attttacaga
    10201 tacaataaag gcagcatgtg gtctggcaga tccaaatgca gtttggggaa tgacacaggc
    10261 agcaccggag ctggtgcact ggctgctaaa acttggagtt aaatttaaca tgagtggcta
    10321 tgatgatgtg gatctgcgga attttggcgg gcagaaaaag aaacggactg cttttgcaca
    10381 gagcgatacc gggaagcaga tcatgacagc tatgatagac gctgttcgca ggaaagaagc
    10441 atctggtatg gtagaacggt tcagccatca ttctttccta acacttcgtc tgtgtggcaa
    10501 tatttgttgt ggctgcgtaa tcagggatga atacagtcag gagactgtgg aattaccggg
    10561 ggatgcggtt attgttgcca ccggtggtat gcacggattg tttggaaata caacgggttc
    10621 gctgagcaat acaggagaag tcaccgcaga attgttccgg cttggtgttc ctctggcaaa
    10681 tagcgagatg atccagtacc atccgacaac tgtgaaatgt ggtggaaaac gcatgctcat
    10741 cagcgaggcg gccagagggg aaggtggcag gttgtttgcc atgaaagatg gaaaacaatg
    10801 gtatttcatg gaggaaaaat acccggagct tggaaatctg atgccacgag atattaccgc
    10861 cagagagata tggaaggtca gccatgaatc agaggtattt cttgacatga cggaaatatc
    10921 ggaggagatt atttcaaata agctatctgg tctggcagac gattgtatga cctatctgca
    10981 taaagatata cgaaaggaac cggtgtctgt tttaccggga attcactatt ttatgggagg
    11041 cattctggtg gatgagcagc acagaacgcc gattcagaat ctttacgctg ccggagaatg
    11101 ctgtgcccaa tatcatggtg ccaaccgtct tggtggaaat tctctgttag gagcgttata
    11161 cggaggacgt gttgcggcaa aatcagcacg tgaacaggca gatgtagtag atctatcttg
    11221 tgcgacacag atagattttc caccaacgtc tcaaatttca gaaataaagc aattaaacaa
    11281 agtgatgcag gatactatgg gcgttgtcag aaatgagaat acgttgttaa atgggattca
    11341 aacggtacaa gcgctgacag gaaatcttcc attgcttggc atggcagttc taaagagtgc
    11401 tcttgcaaga aaagaaagcc gtggtgcaca ctggcgggag gattatccga agagcaatga
    11461 cgatgattac cttaaaacaa cggtagccag atttgatgga aagcagatac agatttcctt
    11521 tgtacctgtt ccagaaaggc ggtgattcac ttggtatata aaataagaat caggcggcag
    11581 gagagtcaga aatcagacag ttattggcag gaatttgagt ttgacggaag caaaaacagc
    11641 tctgttgcca atgttctaaa ggaattgaac agtagaaccc ctttgaaaga taattcaggg
    11701 aatatagtta ctcccatcag ctgggaatgt agctgtatgg tgcgaaaatg tggggcttgc
    11761 gccatgctga ttaacgaacg tccgaggctg gcatgctcta catttctaca tacgttaaaa
    11821 ggttctacaa tcaccttgga acctttaagc aaatttccgc ttgtaagaga tttgatcgtt
    11881 gaccggtcaa ttctgtttga aaatttgaaa aaactgaacc tttggcttga aagtgaagct
    11941 tatatgaatc ggtggacaca tgaaccgaga taccagtcgg cacgctgtct aatgtgtggc
    12001 tgctgccttg aagtgtgtcc taacttctct gcaaatggga ctttcgcagg cgctgttgct
    12061 gcagtcaacg catttcggat tctgaatgaa gaacaggaaa gcactcattt gaatgagatt
    12121 tctgctgaat ataagaagaa atattttgag ggatgcggga agtcgttatc ttgtcatgat
    12181 atttgtccga ttggtctgcc tctggaagaa ctgcttgtaa ggtcgaatgc agcggctgtt
    12241 tggggcaaat aaaatggatg ataaaagcta taatgaatgt atgaagagaa tcaaaaactt
    12301 aagacatgga tcacaccgga tcttgcgacg gagtatctcg caggagccgt gcttctcgga
    12361 gcagctccat gtaccgctat ggtatttgtc tggagtacgc tgacaaaggg aaatccagct
    12421 tatacagtag ttcaggtggc atcaaatgac attattatat tatttgcatt tgtaccgatt
    12481 gtgaaatttc tgcttggtgt ttctaatgtt agtgttccgt ttcagacgtt atttatgagt
    12541 gtggttctat ttgtagtaat accacttgta gccggaatca taacaaggct gctggtagtc
    12601 agaaagaaag gtacggaata ctttgagcag acttttctgc ataaatttga ttccgcaaca
    12661 acagtgggac ttttgctcac gctgatactg atttttatgt ttcagggcga ggtggtgctg
    12721 gacaatccac tgcacattat attgattgca gttccgctga tcattcagac attctttata
    12781 ttctctctgg catttggagt atgcagaatt atcagacttc cgtatgatat tgcagccccg
    12841 gctggaatga ttggtgcatc gaatttcttt gagctagctg ttgcagtcgc tgtagcttta
    12901 tttggtacat caagtccagc ggcactggca actacagtag gtgtattaac agaagtcccg
    12961 gtaatgctta ctcttgtgaa gattgcaaac aaattaaagg agaagttcaa gtatgaataa
    13021 gaaaaaagtt gcttttatat gcgttcataa ttcatgcaga agccagattg cagaagcttt
    13081 gggaaaacat ctggcttcgg atgtatttga aagttattcg gcagggacag aaacgaaact
    13141 acagattaat caggatgcag tccggattat gaaagaattg tatggaattg atatggaagc
    13201 agaaggacaa tatagtaagc tgattgatga gataccagta ccggatattg caatttcaat
    13261 gggttgtaat gtgggatgtc cgtttatcga aagaccgttt gatgacaatt ggggacttga
    13321 agatccaacc ggaaagagtg acgaagagtt taagaaggtt attgatgaga taaggatgca
    13381 aatttttata ttgaaacaac gattggatga atttgaagaa aactaaagaa gttgagaaat
    13441 tgcagttgat atttcactta ttttaggata tttaataact gttatatttg attatcaaat
    13501 tcctcataaa cccttgaaaa tactaagttt gtagcaagtg aactttccct tactctttcc
    13561 cttgcgttat attctcccat tggctttcat gaaccttaat atgggaaaaa ttaagggaaa
    13621 gaaaatttca taacacagta taacatataa caataatgac atggtgaact gattgaaatg
    13681 ttttcgatat ttaactctgt aactgatgat taaaagaaaa tggagataag atacgatgag
    13741 aacaatttat gcagaataca acataaacca cgatagtatt gatgtttaca caagtgctgg
    13801 atatatgctt cgcattgatt gctgggaagc tgaaaaagat ttaaaaacca catatggatc
    13861 agaatgtgcg cttacttcat tggctgtgga tgaacctttg gaatatgcga gattatatct
    13921 taatggtaat ttacagatgt gggtggatgc agaagattca cttgaattat aggcaattta
    13981 aacaaaagtt tatatctgat ttttgattgg aaaaatgaac gagatgcaaa caaggcaaga
    14041 gactcgttaa cacagatatt ttttacataa tcaaagtggc aggggagaaa tctctgccgc
    14101 ttttcttctt agtaggacca ttcataattc atttattgat attattcctt tgaacgagta
    14161 tcctcctacg ccaccatgtt tgttttagaa tattatttgc acgaaaaatg gcggatttga
    14221 aaccgccatc aagtttttta tcctttttgt ttaggaaagc acactacaat ttcaaaaaca
    14281 ttattattta gagaagcact gatagaaccg cccattttta ctgttaaatt ctttgctatt
    14341 gtgagaccca aaccggttgt tttgcgggaa cgggataaat ctgttgtata aaaacgatta
    14401 aatattttgt ctatatcaga ttcatttatg ctgtctgtaa aattctgaaa agaaaaatgg
    14461 taattttcat tatcatcata agatgaaaaa tgataatcac ttttcccatg tgacaaggca
    14521 ttagaaatga tattttcaaa aattctggtt actgcttttt catctccata aaatggaaaa
    14581 gaaatctctg caatacttaa tactggaatg attttgcgtt cctcaaaaga tttaaaaaag
    14641 gaaactgcaa cagagcgtaa aacagcattt aaatcaaatg tagtataaga aaaatccatt
    14701 tcatcagcct ctattcgtgc aaattcaaac aactgattta gtaactgatt taaaacattc
    14761 aatctttcgt ttataataac tgctgcatct aaatcttcct cggacaactc aggtgattgt
    14821 agaagcattt gtgtatagcc ttgaatagca gtcacaggtg ttctaagatc atgggctaaa
    14881 tttgtaattg tttctttgat tgcctcatcc tttttttgta atgaatatac ttgtttgtgg
    14941 taaactcgaa gcaattcatt taaagcattt acaagatcgg ttatatcgga agaaggaaaa
    15001 tctaatgtca attccgcatg ggtaaatgaa tgtaaaagtg tttgcaattt ctggcttaac
    15061 cgggttacct ccctacgatg aaacaagtaa aatgataaaa caataataag agatagtgtc
    15121 acaatgatag catatatttg aagtaccaca ctcataacat tatccctccc tgcattatgt
    15181 aatatctctt ttcttgaaaa ttgttcctat aactccacca aatataatca tataggcgaa
    15241 gaaaatgata attgcggttg gaagccattg aactgccata tctattcttg ttttattgat
    15301 attactaatt gcccaaaaaa ttgtgatgtt atatcctaag cccaaaatac tttccaatcc
    15361 atgaagaacc agataaccaa aaaatataag caaagcatta actgccatgc taactgaact
    15421 gtttcttatg agaaaaacaa ggctttcctg ttccttcttt tccatttcaa gcattcgttc
    15481 ttcataactt tt
//
