LOCUS       c00111_gnlPro..        13419 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MBCGPLPJ_167.
ACCESSION   c00111_gnlPro..
VERSION     c00111_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 02:23:48
            Original ID  :: gnl|Prokka|MBCGPLPJ_167
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13419
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13419
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[122:8538]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      123..8538
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13419
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13419
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(59..184)
                     /locus_tag="ctg111_1"
                     /transl_table=11
                     /translation="MPMTPNTEQDWKAWRNLMWSEILTESVKSYMDCKCLNAISI"
     CDS             complement(123..1640)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg111_2"
                     /sec_met_domain="Fer4_7 (E-value: 1.2e-11, bitscore: 35.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.5e-11, bitscore: 33.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.9e-06, bitscore: 16.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGLYSSKTEIRHKIFTEIARMAYEGQSPEMLEELPYKIVPGEIA
                     TYRDSIFLERAVVGERLRVAMGMSLRKVTEHAPISKGVEASVIEEKYYEPPLINVIKFA
                     CNSCPEKRVMITEGCQGCLEHPCVEVCPKKAVHMEGGRSHIDEDACIKCGKCLEACPYN
                     AIIKQERPCSKACGMNAIGSDEYGRAEIDQDKCVSCGQCLVSCPFSAIVDKGQIFQTIM
                     ALKSETPVYAIVAPAIAGQFPGMENNKIRGAFQALGFTDVREVAVGADLCTVEEAKDFL
                     EEVPEKLPFMATSCCPSWSMMAKKLFPEQAKCISMALTPMVLTARLIKQKEPDCKIVFV
                     GPCAAKKLEASRKSIRSYVDFVLTFEEVAGMFDAKGVDWKDIPEGEPLFHASADGRGFA
                     VSGGVAEAVVHAVKRIDPDREVKVMNAEGLQNCKKMLQMAKIGKYNGYLLEGMACPGGC
                     VAGAGTIQTVKKAAAALEKMKKEASFTDAYDSKYRARLESLEKFDVE"
     CDS             complement(1906..2688)
                     /locus_tag="ctg111_3"
                     /transl_table=11
                     /translation="MIFTKKYRTGQIVLAACIAAVCMFSDVHGAEVAGPPAPKSKSALT
                     QKPEATPMPEATPIPASTPTPEQETETDKQNPADQGTLSKPDHPDTISADKLVFIGDSR
                     TEGLRDAVNDDSIWSCLSSMGYDWMVSTGVPQVEDQIEDNTAVIILMGVNDLYHVNDYI
                     SYINSKAAEWGNRGAQTYFVSVGPVQNDPYCSNAEIESFNAAMQASLSGVTYIDVYSHL
                     VSEGFSTVDGTHYPDSVSVDIYNYILDHLEEQMSGIWG"
     CDS             complement(2666..2794)
                     /locus_tag="ctg111_4"
                     /transl_table=11
                     /translation="MAGYAAWDVSMLLFTATHSRELRYVKSNVSITAEGNDIYEKI"
     CDS             complement(2767..3021)
                     /locus_tag="ctg111_5"
                     /transl_table=11
                     /translation="MRLEKVQEALKTKKIHYEYTEENGCGSIDFMFRGLRFHIWEYEDR
                     VWGAETNVFEAGRSQDIEGDYEEIISGEILSWPDMLPGM"
     CDS             complement(3691..5331)
                     /locus_tag="ctg111_6"
                     /transl_table=11
                     /translation="MKGLLKFITCGSVDDGKSTLIGHILYDAKLLYADQEKALELDSKV
                     GSRGGAIDYSLLLDGLMAEREQGITIDVAYRYFTTDNRSFIVADTPGHEEYTRNMAVGA
                     SFADLAVILVDASQGVLVQTRRHARICALMGIRYFVFAVNKMDLIEYDEKRFRDIENQI
                     AALIEELKLANVTIIPVSATEGDNVTTKSDNMPWYKGEALLSHLETVDIKEDTEKGFYM
                     PVQRVCRPNHEFRGFQGQIENGVIRAGDLVTTLPSKEEAHVKSILVGDKEVQEAVQGQP
                     VTIQLDREVDVSRGCVLTIDSGAVLTDSVEADILWMDDNALTDGKNFFVKIGTKMIPGL
                     VTKINYSVDVNTGEKKSAYTLKKNEIASCTLEFSEKIVVDEFDRHRTLGELILIDRVTN
                     MTSACGVVRKTFVSQDRSQIGKVDEQVRAGLKGQTPVVVEFPIGKEGITLDFAEQVEKG
                     LTVLGKHTYLYHPAASENYAETVRHLKAAGLIVLLVLDENTAKDETLKTLDGFYANWQI
                     DGITVKDAIDFVKKKSAFTVQSVHDGNYI"
     CDS             complement(5333..6451)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAPS_reduct"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg111_7"
                     /sec_met_domain="PAPS_reduct (E-value: 4.2e-65, bitscore:
                     208.9, seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VCLKNALRKMCVTICGRFCSDEGVVAGYDNRIRTKYTAKWGVQIA
                     GMIFQTRSSVFAQVRKDSEYKQTEEDNAMSNLSHLDALEAEAIYIMREVAAECEKPVML
                     YSIGKDSSVMLHLAMKAFYPEKPPFPFLHIDTTWKFHEMIEFRDRIAKENGIDMLVYTN
                     EEGVKAGINPFDNGSAYTDIMKTQALKQALTKYGFTAAFGGGRRDEEKSRAKERIFSFR
                     NSAQAWDPKNQRPEMWKLYNTKIQKGESMRVFPISNWTEKDIWQYIQRENIEIVPLYFA
                     KERSVIYRDGNIIMVDDDRLKLRPGEKIENKKVRFRTLGCYPLTGGIESEADTLDEIID
                     ETLSAVSSERTSRVIDHEAAGSMERRKREGYF"
     CDS             complement(6482..6796)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg111_8"
                     /sec_met_domain="Fer4_9 (E-value: 1.8e-13, bitscore: 40.4,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.7e-09, bitscore: 26.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.7e-05, bitscore: 14.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIRIQKSKCAGCGRCIEACPGNLIKKDKENKAFIRQVRDCWGCT
                     SCIKECRHDAIRFFLGADVGGRGASMVVSEKPDISTWTVEKPDGTKITIQVNKKDANKY
                     "
     CDS             complement(6793..8538)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 70; E-value: 6.9e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg111_9"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.5e-22, bitscore:
                     70.0, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-08,
                     bitscore: 24.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTERIRTDVLIIGGGTAGCFAAYVIGKKSGRKVLIAEKANIKRS
                     GCLAAGVNALNAYITEGRVPQDYVDYAKKDAHGIVREDLLLTMSERLNHVTKVMEDLGL
                     VILKDENGKYVARGNRNIKINGENMKPILAKAAAEQENVTVLNHVNITDYKTENKKVTG
                     AVGFSVNEDIFYDIDAKAVLCATGGAAGLYRPNNPGFSRHKMWYPPFNTGAGYAMGLLS
                     GAEMTTFEMRFIALRCKDTIAPTGTIAQGVGARQVNAYGDIYETKYGLTTSQRVYGTVM
                     ENREGNGPCYLRTEGISKEQEQDLYKAYLNMAPSQTLKWMEAGKGPSEENVEIEGTEPY
                     IVGGHTASGYWVDNNRATTIEGLYAAGDVAGGCPQKYVTGALAEGEIAAEAILEYLNGK
                     DDDRIAAENKEEALERGGEQELSQTAIAKKAEYESHLNASRSLMNAEQLEEAMQKIMDQ
                     YAGGIGTDYRYSGMSLAKADEKIAALLPVVDTLAATDTYELMQIYELRERLIVCQAVIA
                     HLAARKETRWHSFGENTDYPQQSEEWMKYVNSRMENGEIKILYRDLITKENTGLNTAEK
                     GAGER"
     CDS             complement(8650..9708)
                     /locus_tag="ctg111_10"
                     /transl_table=11
                     /translation="MYVELKNINKTYGSYQASRNVNFGIEKGKLIGLLGPSGSGKTTIL
                     RMIAGLETPDSGEVIIDGKVVNDVPASQRGIGFVFQNYALFRYMTVYDNVAFGLKVQKA
                     DKKKIDARVRELIKLVGLEGLEKRYPSQLSGGQRQRVAFARALAPNPQVLLLDEPFAAI
                     DAKIRQELRSWLKEMIGKLGITSIFVTHDQDEAIEVADEIIITNAGRIEQKGTPIGVYR
                     NPETAFTASFFGQPSVLKDADDFHTFAQAEGADKIIVRPEFVKISKLDEVEKFKTSVSR
                     GVVERVSFRGDNLELQVRVNNSVVTARRSLEKADIREGETVNVFLYRIFALRGDSVQLI
                     ENEAVRDDFVII"
     CDS             complement(9710..10534)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 60.2; E-value: 7.2e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg111_11"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.6e-19, bitscore:
                     60.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNNEKTSEKITKWLLVVISVLFLAVMLLLPLITVITEALRSGWK
                     VYAAAVTDEYTIKALLLTVKATLFAVGFNTIFGIFAAWALTKFQFRGKKFLTTLIDLPV
                     TISPVIAGLIFLLIFGRQSPVYFFLMKLGIKVVFSVPGIIIATVFVTFPFISRELIPVL
                     EAEGSDEEEAAALMGAGGWTIFWKITFPHIKWALLYGVVLCTARAMGEFGAVSVLSGHL
                     RGKTNTLPLHVEILFNEFQYVPAFAVSSLLVIMAVIILVVRSLIEYKGKKEA"
     CDS             complement(10534..11370)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 83.4; E-value: 5.4e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg111_12"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.2e-26, bitscore:
                     83.4, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRNKPVIPGFELSMGITISILSLVVLIPLASLVVYTAKLSFKD
                     IIETITRARVLASFYTSFVCAFAAAVINGIMGTILAWVLVKYDFPGKRLMDGMIELPFA
                     LPTAVAGIALTSLTSDSGIVGSFFAGFGIKIAYTRIGITVAMIFVGIPFVVRSVQPVLE
                     KMDNSYSEAAGVLGAKKTTIFWKVIFPELKPAIFAGTGLAFGRCLGEYGSVVFIAGNKP
                     YYTEITPLVIMSELQEFDYSSATAIALVMLAVSFFILFLNSMIQQRNARILRGGNA"
     CDS             complement(11441..12439)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SBP_bac_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1044:Bacterial extracellular solute-binding protein
                     (Score: 57.1; E-value: 9.3e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg111_13"
                     /sec_met_domain="SBP_bac_1 (E-value: 2.1e-18, bitscore:
                     57.1, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRKLFAFGLAVVLALMPVQAFGKTVSVTNVSYDPTREMFEQYNK
                     IFEDHWKEKTGEDVEVIQSHGGSGKQALEVANGLDADVVTLALEYDIESIENAGLIKAG
                     WKDKFDNDSSPYTSTIVFLVKKGNPKDIKDWDDLTKKGVGVVTPNPKTSGGARWNYMAA
                     WAYADKKYGGDEAQMKEFIKKLYRNVVVLDSGARGATTSFVENGQGDVLVAWENEAYLS
                     MRDYPDEYEIVTPSVSILAQPSVAVVDEVVDYRDTRDVATEYLNYLYSDEAQEIAAENY
                     FRPTNEKILKKHSDTFDLNINLANISDYGGWDKVQEKHFTDGGIFDQIYER"
     CDS             complement(12642..13130)
                     /locus_tag="ctg111_14"
                     /transl_table=11
                     /translation="MPKNKFQEVIFTIIMVFVMVYAMICYNIVLNTGTMTNETFLLAFH
                     ELTFMGPIAFILDFFIIGGLAKKIAFGIVDMRRDNPFHLVLAISAVSVAFMCPCMSFAA
                     TVLIKHAPASQIIPTWLQTTAMNFPMAFFWQIFYAGPFVRFIFGKLFPEKEKAAASAE"
ORIGIN
        1 cggtatcccg ccttaattca gatgctctgg taactcagtt gccgagtaat tcactctgct
       61 atatactgat tgcattcaaa cacttgcaat ccatatagga tttcactgat tcagtcagaa
      121 tctcactcca catcaaattt ctccaggctt tccagtcttg ctctgtattt ggagtcatag
      181 gcatctgtaa acgaagcctc tttcttcatt ttttcgagag ctgctgctgc ttttttaact
      241 gtctggatag taccggcacc tgctacacag ccgcccggac atgccattcc ttccaaaaga
      301 tatccattat atttaccaat cttggccatc tggagcatct tcttacagtt ctgcagacct
      361 tctgcattca ttacctttac ttcccgatca ggatcaatac gcttcaccgc atggacaacc
      421 gcttctgcca caccaccgct gactgcgaaa cctcttccgt cagcactggc atgaaacagt
      481 ggttctcctt ccggaatatc tttccagtcc acgcctttgg catcaaacat tcctgctact
      541 tcctcgaagg tcagcacaaa atccacatag ctgcggatac tcttacggct ggcttccagc
      601 ttcttggctg cacagggacc tacgaaaacg atcttacaat ctggttcctt ctgcttgatc
      661 agccttgcag tgagaaccat aggtgtcagt gccatagaga tacatttcgc ctgttccggg
      721 aataatttct tagccatcat agaccaggac ggacaacagg atgtagccat gaaaggaagt
      781 ttctcaggaa cttcttccaa aaagtccttt gcctcctcca ctgtgcacag atctgcaccg
      841 acggcaacct ctcttacatc tgtaaagcca agtgcctgaa atgctccccg tatcttatta
      901 ttctccatac ccggaaactg gcctgcaatg gcaggcgcca cgattgcata caccggtgtt
      961 tcacttttta atgccataat agtctggaaa atctgtcctt tgtctacaat agcactgaac
     1021 ggacaactta ccagacattg tccgcaggat acacatttat cctgatcaat ctctgctctt
     1081 ccatattcat cagagccaat agcattcata ccgcatgcct ttgaacatgg acgttcctgt
     1141 ttgatgattg cattatacgg acaggcttcc agacactttc cgcatttgat acaggcatct
     1201 tcatcaatat gggatctgcc gccttccata tgcactgctt tctttggaca gacttccaca
     1261 cagggatgct ccaggcaccc ctgacagccc tctgtgatca ttaccctttt ttcagggcag
     1321 gaattacagg caaacttgat cacattgata agcggcggtt cataatactt ttcctcaata
     1381 acgctggcct ccacaccttt ggaaattggc gcatgctctg taacctttct cagtgacatc
     1441 cccattgcaa cgcgaagtct ctcaccaact accgctcttt ccagaaaaat actgtcacga
     1501 taagtcgcaa tttcaccggg tacgatcttg tagggaagct cttccagcat ctccggagac
     1561 tggccttcat atgccatcct cgcaatttct gtaaaaattt tgtgtctgat ttctgttttg
     1621 gatgaataca gtcctctcat tttttcctcc tgattttcga ttcggataac tgtacggcaa
     1681 tccaatgcag ggacaccgaa caatttccat ttataatttc atcactgctg caatcagcac
     1741 actcattttt cctcctgctg aactttcagc cacttcacag agaaacgaaa ttccgctcat
     1801 ttccgtttcc ttatctgcat atcatatcac caaatgcttc caggctcaac acaacatcag
     1861 aattttcgct gaattgtcgc ccccgaagtt gctgttcata tgttgttatc cccagattcc
     1921 actcatctgt tcctccagat ggtccaagat ataattataa atatctacgg acacactgtc
     1981 cggatagtgg gttccgtcta cggtggaaaa tccctcagat accagatggg aatatacgtc
     2041 tatgtaggta actccactca ggcttgcctg cattgccgcg ttaaaacttt caatctccgc
     2101 attactgcaa tagggatcat tctgcaccgg acctacagac acgaaataag tctgcgctcc
     2161 tctgttcccc cattcagcag ctttggaatt aatataactg atgtagtcat tgacatgata
     2221 aagatcatta acacccatca ggataataac cgctgtattg tcctcaatct gatcttctac
     2281 ctgcggcact cctgtagata ccatccagtc atatcccata gaagaaagac aggaccaaat
     2341 gctgtcatcg tttaccgcat ccctcaatcc ctctgttctg gaatctccga taaataccag
     2401 tttatctgcg gagatagtgt ccggatggtc tggcttgctt aaagttccct ggtctgccgg
     2461 attctgttta tctgtctcag tttcctgctc cggtgttgga gtagatgcag gtattggtgt
     2521 tgcttcaggc attggtgttg cttcaggttt ttgtgtcagt gccgatttgg atttcggtgc
     2581 cggcggacct gccacttctg ccccatggac atctgaaaac atacagacag ctgcaataca
     2641 tgcggctaat acgatttgtc cggttctata ttttttcgta aatatcattc ccttctgcag
     2701 taatacttac gttacttttc acatatctca actccctgga gtgtgttgct gtgaacagta
     2761 acatacttac atcccaggca gcatatccgg ccatgagagg atttctccgg aaataatttc
     2821 ctcgtaatct ccctcaatat cctggcttct gcctgcttcg aacacgtttg tctccgctcc
     2881 ccagacacga tcttcatatt cccatatatg gaatctcaga ccgcgaaaca taaagtcgat
     2941 gcttccgcat ccattttcct ctgtatattc ataatgaatt ttctttgttt ttaacgcttc
     3001 ctgtactttt tccaaacgca taaaatacct cctgattatc tatacagtac cctctgtaat
     3061 ataatacaga taactttcac tgtaaaaaaa tgttctcgtg tacacccatc aaaagtcaaa
     3121 cagatattcg caatccgctt cgctacacag ctctacatat gctcttaatc ctgacgccat
     3181 tatacaaaac gaattatatc atactctgct gcataatatg taatctgaat gccacttcac
     3241 aattgccgtt actgttcact ccgttcatag taacttagcc aaaattcatt ccagattgcc
     3301 tgtggcaatg gaattttggc ttgtatgtct cgggattttg gcatattcat gccaaaacac
     3361 ctcgcgggat aatggtgtgt gaacagtaac caattgccca ttctacattc tgatcgatat
     3421 tcactcatct ttatttctgt cttttcttcg ttggtatcgc caggatgatg atcgtagcaa
     3481 ttacaaacaa agttccaagc atcatctctt tttttggttt tgtttacttt cattgttcgt
     3541 ttgcatattt ctgttatctt tcctgtctgt attattatgg attctgaata tttgaaaata
     3601 agtataatcc gctgtaacga cacttgtcaa gaaaacaaaa taccgcagag actttctttg
     3661 tctctgcggc gatttatagc cctgttataa tcagatataa tttccatcat gtacactctg
     3721 cactgtaaat gcagatttct ttttcacgaa atcaatcgca tctttcacag tgattccgtc
     3781 aatctgccag ttcgcataga aaccatccag agtctttaat gtctcgtctt ttgctgtatt
     3841 ttcatcaaga acaagaagta cgatcagacc tgctgcctta agatggcgga cagtttctgc
     3901 atagttttca ctcgctgccg gatgatacag ataggtatgt tttccaagta cagtcagtcc
     3961 cttttctacc tgctctgcaa aatcaagagt gattccttct ttaccgatcg ggaattccac
     4021 tactaccggt gtctgacctt tcagtcctgc acgaacctgc tcgtccactt ttccgatctg
     4081 agatctatcc tgagaaacaa aggtttttct cacaacaccg caggcagaag tcatatttgt
     4141 gacacgatct atcaggatca gctcacccag tgttctgtgc ctgtcaaatt cgtctacaac
     4201 gatcttctct gagaattcca gagtacagga agcaatctca tttttcttta aggtatatgc
     4261 gcttttcttt tcacctgtat taacatccac agaataattg atctttgtaa ccaggccggg
     4321 gatcatcttt gtaccgattt ttacaaagaa gttcttgcca tccgtaagag cattgtcatc
     4381 catccagagg atatctgctt ccacagagtc tgtaagaact gcgccggaat caatggtaag
     4441 tacacatccg cgggaaacat ctacttctct gtcaagctgg atggtaacag gctgtccctg
     4501 tacagcttcc tgaacttctt tatcgccaac aagaatactc tttacatgag cttcttcttt
     4561 actgggaaga gtagtcacaa ggtcgcctgc cctgatgaca ccattctcaa tctgtccctg
     4621 gaatccgcga aactcatggt ttggtctgca gactctctgt acaggcatat agaagccctt
     4681 ctctgtatct tccttaatgt ctacggtttc cagatgggaa agaagcgcct cacctttata
     4741 ccatggcatg ttgtcagatt tggttgtaac gttgtcacct tctgtggcag ataccggaat
     4801 aatagttaca ttggcaagtt tcagttcttc tatcagtgct gcgatctgat tctcaatgtc
     4861 gcggaaacgt ttttcatcat attcaataag atccattttg tttactgcaa atacaaagta
     4921 acggattccc atcaatgcgc agattcttgc atgacgtctt gtctgtacca gtactccctg
     4981 tgaagcatcc accaggataa ctgccagatc tgcaaaggac gcacccactg ccatgtttct
     5041 tgtatattct tcatgtccag gtgtatctgc aacaatgaag cttctgttat ctgttgtaaa
     5101 ataacggtat gcaacatcaa tggtgattcc ctgttcacgc tctgccatca gaccgtccag
     5161 aagaagagaa taatcaatgg caccgcctct gcttcctact ttggaatcca gctccagagc
     5221 tttctcctga tctgcataga gaagctttgc atcataaaga atatgtccga tcagagtgga
     5281 ttttccatca tccacacttc cgcatgtaat aaatttcaat aatcctttca ttctagaaat
     5341 acccctctct ctttcttctc tccatgctgc ctgctgcctc gtggtcgatc accctgctgg
     5401 tacgttcaga agaaacagca cttaacgtct catcaataat ctcatccaga gtatctgctt
     5461 cagattcaat acctccagta agcggatagc acccaagagt acggaatctg acttttttgt
     5521 tttcaatctt ttcacccgga cggagtttta atctgtcatc atccaccata atgatatttc
     5581 cgtctctgta gatgaccgat ctttctttcg caaaatataa cggtacaatt tcgatatttt
     5641 cacgctgaat gtactgccag atatcctttt ctgtccagtt ggaaattgga aatactcgca
     5701 tactctcgcc cttctggatc ttagtgttat aaagcttcca catctccggt ctctggtttt
     5761 tcggatccca tgcctgagct gaattacgga aagagaagat tctttctttt gctctggatt
     5821 tctcctcgtc acggcggccg cctccaaatg ccgctgtaaa tccatatttg gtcagagcct
     5881 gttttaacgc ctgtgttttc atgatatctg tatatgcaga accattgtca aatggattga
     5941 ttcctgcctt tacaccctct tcattggtgt aaaccagcat atcaattccg ttttcctttg
     6001 cgattctgtc gcggaattcg atcatctcat ggaatttcca tgtagtatca atgtgaagaa
     6061 agggaaaagg cggtttctcc gggtaaaatg ccttcatcgc cagatggagc ataacggagc
     6121 tgtcctttcc tatagaatag agcataaccg gcttttcaca ctcggctgct acttcccgca
     6181 taatataaat cgcctctgcc tcaagcgcat caagatgaga taagttactc attgcattat
     6241 cctcctctgt ttgtttatac tcggaatctt ttcgtacttg agcaaataca ctagagcgtg
     6301 tctgaaaaat cattcccgca atctgcacgc cccactttgc ggtatatttt gtccgaattc
     6361 ggttgtcgta gcccgctacg acgccctcat ccgaacaaaa tctcccacaa attgtgacgc
     6421 acatcttgcg taaagcattt ttcaaacaca ctctaaagac tctgagagta catacttatg
     6481 tttaatattt attagcgtct ttcttattaa cctgaatagt gatcttagtg ccatccggct
     6541 tctccactgt ccatgtggaa atatccggtt tctctgatac aaccatactt gcacctctgc
     6601 cccccacatc agctccaagg aaaaagcgga tggcatcatg cctgcattcc ttgatacagg
     6661 atgtacatcc ccagcagtct cttacctgac ggataaaggc tttgttctct ttatcctttt
     6721 tgatcagatt tccgggacag gcttcgatac atctgccgca tcctgcacat ttacttttct
     6781 gaatccgaat gctcatctct cacctgctcc tttctctgct gtattcaaac ctgtattttc
     6841 ctttgtgatc aggtcacgat ataagatctt aatctcgccg ttttccatac gggagtttac
     6901 atatttcatc cactcttcgc tctgctgcgg gtagtctgta ttctctccga aactatgcca
     6961 tctggtttcc tttctggctg ccagatgtgc gatcactgcc tggcacacga tcagtcgttc
     7021 gcgaagttca taaatctgca tcagttcata agtatctgtt gctgccagag tgtcaactac
     7081 tggcaacaat gctgcaatct tttcatctgc ctttgcaaga ctcatcccgc tgtatctgta
     7141 gtctgtaccg attcctcctg cgtactgatc catgatcttc tgcatggctt cctcaagctg
     7201 ctctgcattc atcaaagaac gggaagcatt caaatgtgat tcgtattctg ccttcttagc
     7261 tattgcagtt tgagacagct cctgttctcc gccacgctct aaagcctctt ccttattttc
     7321 cgctgcgatc cggtcatcat ctttgccatt cagatattcc aaaatcgcct ctgctgcgat
     7381 ctcaccttct gccagtgcgc cggttacata tttctgcgga catcctcctg ctacgtctcc
     7441 ggctgcatat aaaccttcaa tagttgtagc tctgttatta tctacccagt aaccgctggc
     7501 tgtatgtccg cctacaatat atggctctgt gccctcaatc tctacattct cttcggatgg
     7561 tccttttccg gcttccatcc atttcagagt ctgggacggt gccatattca ggtaagcttt
     7621 gtaaaggtcc tgctcctgtt ctttggaaat accttccgtt ctgagataac atggaccgtt
     7681 tccttctctg ttctccatga ctgtaccgta aactcgctgg gaagttgtca gaccatattt
     7741 tgtttcataa atatcaccat atgcattgac ctgtctggcc ccaacgccct gagcaatagt
     7801 tcctgtagga gcaatcgtgt ccttacatct caatgcaatg aaacgcatct caaaggttgt
     7861 catctccgca ccggaaagaa gtcccattgc atatcctgca cctgtgttaa acggaggata
     7921 ccacatctta tgtctggaaa atcccggatt attcggtctg taaagtcccg ctgcaccacc
     7981 tgtggcacaa agaactgctt tcgcatcaat gtcatagaaa atatcctcat taacgctaaa
     8041 tccaactgcg cctgtgactt ttttgttttc tgttttataa tctgtaatat ttacatgatt
     8101 gagaaccgta acattctcct gttcagctgc cgcctttgca aggattggct tcatattttc
     8161 gccattgatc ttgatgtttc ggtttcctct ggcaacatat tttccgtttt cgtccttcag
     8221 gatgaccagc cccagatctt ccatcacctt tgtcacatga ttcagtctct ctgacatggt
     8281 aagaagaagg tcttctctta cgattccatg ggcatccttt ttggcataat ccacataatc
     8341 ctgcggcact ctgccttctg taatatatgc gttcaatgca ttcacgcccg ccgccagaca
     8401 tccgcttcgc ttaatattcg ctttctctgc gatcagaact tttctgccgc tttttttgcc
     8461 gatcacatag gctgcaaagc atcctgccgt accgccgccg atgatcagca catctgtcct
     8521 gattctctct gttctcattc tctcttaccc tttcctccat accagtgtac caacaagttg
     8581 atttcccgat cagtcttgcg tctgaatttc ttatttcttc attgtcgtca gtcgccgcag
     8641 ccaccgctgt cagataatta caaagtcatc ccttacagcc tcattttcga tcagctgtac
     8701 actgtcacct ctcagtgcaa aaatcctgta aaggaataca ttcacagtct caccttcccg
     8761 gatatctgct ttctccaggc ttcttctggc agttactacg gaattgttga ctctcacctg
     8821 aagttccaga ttatctcccc tgaaagaaac ccgttcaacc actccccggg atacggaagt
     8881 tttgaacttc tccacctcat ccagtttgga gatttttaca aattccgggc ggacaatgat
     8941 cttgtctgct ccttctgcct gagcaaaggt atggaaatca tccgcatctt tcaacacaga
     9001 tggctgtccg aagaaggacg ctgtaaaagc tgtctcagga tttctgtaaa cccctatggg
     9061 agttcctttc tgttcgatcc gtcctgcatt agtgataata atctcatctg ctacttcaat
     9121 ggcctcatcc tgatcatgag taacgaaaat actggtaatt cccagcttcc cgatcatctc
     9181 ttttaaccag cttcgcagtt cctgacggat ttttgcatca atggctgcaa agggctcatc
     9241 cagaagcagc acctggggat ttggagcaag ggctctggca aatgccaccc tttgcctctg
     9301 accgccggat aactggcttg gatatctttt ttccagtcct tccagcccca ccagtttgat
     9361 cagttctctg actctggcat caattttctt cttatcagcc ttctgaacct tcaaaccaaa
     9421 tgcaacgttg tcataaactg tcatatagcg aaacaacgca taattctgaa atacaaatcc
     9481 aatcccacgc tgactggctg gaacatcatt taccactttt ccatcaataa tgacctctcc
     9541 gctgtccggg gtttccagac ctgcgatcat tcgaagaata gttgtttttc cgcttccgct
     9601 tggtcccagc agaccaatca gtttaccttt ctcaattccg aaattcacat tccttgatgc
     9661 ctggtaagaa ccatatgtct tattgatatt ttttaactct acatacatat caggcttcct
     9721 tctttccttt atattcaatc aggcttctga ctaccagaat gataactgcc atgatcacaa
     9781 gcagtgaaga tacggcaaat gccggaacat actgaaactc attaaacaaa atctctacat
     9841 gaagaggaag tgtattggtc tttcctctta aatgtccgga aagtacagat accgctccaa
     9901 actctcccat tgctcttgcc gtacagagca caactccata cagtaatgcc catttgatat
     9961 gagggaatgt gatcttccag aaaatagtcc atccacctgc tcccatcagg gctgccgctt
    10021 cctcctcatc gcttccttct gcttccagaa ccggaatcag ttctctggaa ataaaaggaa
    10081 aggttacaaa tacagttgca ataatgattc ccggtacaga gaatacaact ttaatcccta
    10141 acttcatgag aaaaaagtaa acaggactct gtcgtccgaa aatcagaaga aagatcaaac
    10201 ctgcaataac aggggaaata gtaaccggaa gatcaatcag ggtagtgaga aactttttac
    10261 ccctgaactg aaacttcgtc agtgcccagg ctgcaaaaat accaaaaatg gtgttgaaac
    10321 caactgcaaa gagtgttgcc ttcactgtaa gaagaagtgc tttgatggtg tactcatctg
    10381 tcactgcagc tgcatagacc ttccatccgc tccgcaatgc ttctgtgatc acagtgatca
    10441 gaggaagaag gagcatgact gccagaaaca gaacactgat cacgacaagc agccattttg
    10501 taattttctc cgaagtcttt tcattgttgt ccatcaggca tttcctcctc ttaaaattct
    10561 tgcatttctc tgctgtatca tactgttaag gaacagaata aaaaatgaaa ctgccaacat
    10621 cacaagtgcg attgccgttg cacttgaata atcaaattcc tgaagctctg acataataac
    10681 cagcggtgtg atttctgtat aatagggttt atttcctgcg ataaatacaa cacttccata
    10741 ttcacccaga catcttccga acgcaagtcc ggttcccgca aagatcgcgg gcttcagttc
    10801 cggaaaaatg accttccaga agatagttgt tttctttgct cccagcactc ctgctgcctc
    10861 gctgtaagaa ttatccatct tttccagaac cggctgtaca cttcgcacaa cgaacggtat
    10921 ccctacaaat atcatagcca ctgtaatacc tattcttgtg tatgcgatct tgataccgaa
    10981 tcctgcaaaa aagctgccga caattcccga atctgaggtc agggatgtca gtgcaatacc
    11041 cgctaccgct gtgggaagag caaagggaag ttcgatcatc ccatccataa gtctcttgcc
    11101 cggaaaatca tatttcacaa gcacccacgc aagaatagtt cccataattc catttattac
    11161 tgctgctgca aaagcacata caaaactggt ataaaaggat gccaacactc tggcccttgt
    11221 gatggtttcg ataatatctt taaaactcag cttcgctgtg tagaccacca ggcttgccag
    11281 ggggatcaga actaccagac tcaatatgga aatggtaatt cccatggaga gctcaaaccc
    11341 tggaatcacc ggtttatttc tttttttcat aatcaattac cacctctcct gtctcatata
    11401 ttctgtctgt gcttatgctc ttgcttcatc ttgtcttcct ttatctctca taaatctgat
    11461 cgaaaattcc gccatctgtg aaatgtttct cctgcacttt atcccatccg ccataatcac
    11521 tgatatttgc cagatttata ttcagatcaa acgtatcact gtgcttcttc aggattttct
    11581 cattagtggg gcggaaataa ttctctgctg cgatctcctg tgcttcgtcg gaatacagat
    11641 aattcaaata ctcagttgcc acatctcttg tatctctgta atccaccact tcatctacca
    11701 ccgccacaga aggctgtgcc agaatactta cgcttggagt aacaatctca tactcatccg
    11761 gataatcccg catggataga taagcttcat tttcccacgc aaccagcaca tctccttgtc
    11821 cgttctccac gaaagaggtc gttgcacctc ttgcgcctga gtcaagaacc accacattcc
    11881 ggtaaagttt cttgataaat tccttcatct gcgcttcatc gccaccatac tttttatctg
    11941 cgtaagccca cgctgccatg tagttccatc tggcaccgcc ggaggttttc ggatttggtg
    12001 ttactactcc cactcctttt ttcgtcagat cgtcccagtc tttgatatcc ttgggatttc
    12061 ctttcttcac cagaaatacg atagtggatg tataaggaga actgtcattg tcaaatttat
    12121 ctttccatcc tgccttgatc agccctgcgt tttcaataga ctcaatatca tattcaagtg
    12181 ccagggttac cacatctgca tccagaccat tggctacctc cagtgcctgt ttccctgaac
    12241 cgccatggga ctgtatcact tccacatctt ccccggtctt ctccttccag tggtcttcaa
    12301 atattttatt atactgttca aacatctctc tggtaggatc ataggaaaca ttggtgacag
    12361 acaccgtttt tccaaaagcc tgtaccggca tcagtgccag tacaactgca agaccaaagg
    12421 caaataattt tctgatcatg tttcatctcc tttaaggtac cagtagtttt ttgcattctc
    12481 tacttttcat agttattcga tatgttttat atgatattac aagaaatgac agaatttgtc
    12541 aatagtgtat taaaataagt acaatttatg ttgtgtaaat aagaacacaa aaaagcagca
    12601 tcctgaaata cagaatgctg cagtcaaaat tacatatttt tttattcggc agaagctgct
    12661 gccttttctt tctccgggaa aagctttccg aaaataaatc ttacgaatgg tccggcataa
    12721 aagatctgcc agaagaatgc catcggaaag ttcattgctg ttgtctggag ccatgtggga
    12781 atgatctgac ttgccggtgc atgtttgatc agcacagttg ccgcaaagct catacatgga
    12841 cacataaatg caacggatac tgctgagatt gcaagtacaa ggtggaacgg attatctctt
    12901 ctcatatcca caataccaaa tgcaatcttc tttgcaagac caccgatgat aaagaaatca
    12961 agaataaatg caatcggtcc catgaatgtt aattcatgaa aagctaacag aaatgtctca
    13021 tttgtcattg tccctgtatt cagtacaatg ttgtagcaga tcatggcata aaccattaca
    13081 aacaccatga taatcgtaaa aataacttcc tgaaacttgt ttttaggcat aaaaatcctc
    13141 cttagatagt atgaataaca tcaattagag atttgtgttg ttcataacca tccaggagga
    13201 tgtaccgttt ccaataatac caaatatctg tttcttaaat ttaccgttgg ttattatacg
    13261 gactgtttta aaaaaagtca aggatttttt cagtacctgc agtgtgaatc aggaaacaaa
    13321 ggttactgtt cacacaccac tgtcccgcga ggtgttttgg catgaatatg ccaaaatccc
    13381 gagacataca agccaaaatt ccattgccgc aggcaatct
//
