LOCUS       c00157_gnlPro..        16268 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CFBKKHNF_245.
ACCESSION   c00157_gnlPro..
VERSION     c00157_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 05:57:56
            Original ID  :: gnl|Prokka|CFBKKHNF_245
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16268
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16268
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4016:6268]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4017..6268
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16268
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16268
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             162..521
                     /locus_tag="ctg157_1"
                     /transl_table=11
                     /translation="MPKTSYICNCDVIHEDIVNDVKSKMQPKDDYIQLASLFKLFGDGT
                     RVQILHALEQSEMCVCDLAVLLGVTKSAISHQLKALRLANLVKFRKEAQIVYYSLADDH
                     VKEIIDKGFEHLWQK"
     CDS             581..2935
                     /locus_tag="ctg157_2"
                     /transl_table=11
                     /translation="MKRIFLLKGLDCPNCSAKIEKEVGELDGVQSSVVNLMKQTLTINV
                     TQTAADTIASQIETIVYSHEPDVEVQEETIIPVTKSYLLKGLDCPNCSAKIEKEVGELD
                     GVQSSVVNLMKQTLTINVAPVAANTIASQIETIVHSHEPDVEVSEIAQEYYIPAKKQDT
                     NTSYNNEDKKLTIRLAIGAAIYGIGMALTVFAKVPLPVELVFLIVSYIILGGDVVWQAV
                     RNISKGRVFDEHFLMSVSTIGAFVIGEYPEAVAVMLFYQVGEFFQSLAVERSRKSISDL
                     MDIRPDCATVRRNGELITISPESVAIGEIIIVKPGEKIPLDGVVLDGDSMLDTRALTGE
                     SVPRSVHKGDEALSGCMNQTGVLTIKTTKAFGESTASKIIDLVENASSRKAPTENFITT
                     FARYYTPVVVILAAILAILPPILLGGGWTEWIRRGFVFLVVSCPCALVISIPLTFFGGI
                     GAASKRGVLVKGSNYLEALNNVSIIVFDKTGTLTKGVFNVTDILPANGFSKEQVLEYAV
                     QAESFSNHPIAKSILSAYGKEIDQSVISDYKEISGYGISAMAGKKKVYAGNTKLMDSEH
                     VEYTACEKVGTKVYVAVDGQYAGCILITDEVKPDSKKAISDLKHIGVEKTVMLTGDDEK
                     IGKAVAEELQLDEYYAQLFPDQKVEKVELLDSKKRQGSKLAFVGDGINDAPVLARADVG
                     IAMGGLGSDAAIEAADVVLMTDEPSKLVDAIDVAKATKQIVMQNIVIALGIKSVFLILG
                     ALGIAGMWEAVFGDVGVTIIAVLNAMRILKK"
     CDS             2952..3470
                     /locus_tag="ctg157_3"
                     /transl_table=11
                     /translation="VKRKLILLVVTIVFLVGFGVILHSPPSMIDAVTGATPKSKKAAQA
                     SAQLEGSYVLGINMMSDGLDNENTRNKLKELALDDSETNETDLMKTDISFRLYVSETDY
                     PLASYAKKLCDRLKQAGFFVDLKEYSNTMMLSRVVSGKYDVFLASDDFIDVTTLSQMDY
                     MIMDSEEMR"
     CDS             3481..4020
                     /locus_tag="ctg157_4"
                     /transl_table=11
                     /translation="MRKWNTILSVLMLLIFMIHGIMGSFMLNGVGSSAGKLLAWIGVGI
                     LVVHTVIGVILTVQSLQTAKQSGKMYLKQNAIFWARRASGLAILILLFFHIGLFGKVQN
                     GTYILFPFTTVKMVTQLLFVAAIFVHIFINIRPLLVSLGIISYKERRGDIYLILSVLLL
                     FIAGAVIFYYIGWQYL"
     CDS             4017..5561
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 269.9; E-value:
                     1.4e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.8e-83, bitscore:
                     269.9, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.5e-17,
                     bitscore: 52.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTIIIIGAGLAGLSAALQAAENGCNVKLVSSLPSERAQSVMAE
                     GGINAALNTKDENDSPEEHFTDTIKAACGLADPNAVWGMTQAAPELVHWLLKLGVKFNM
                     SGYDDVDLRNFGGQKKKRTAFAQSDTGKQIMTAMIDAVRRKEAFGMVERFSHHSFLTLR
                     LCGNICCGCVIRDEYSQETVELPGDAVIVATGGMHGLFGNTTGSLSNTGEVTAELFRLG
                     VPLANGEMIQYHPTTVKCGGKRMLISEAARGEGGRLFAMKDGKQWYFMEEKYPELGNLM
                     PRDITAREIWKVSHESEVFLDMTEISEEIISNKLSGLADDCMTYLHKDIRKEPVSVLPG
                     IHYFMGGILVDEQHRTPIQNLYAAGECCAQYHGANRLGGNSLLGALYGGRVAAKSACEQ
                     ADVVDLSCATQIDFPPASQISEIKQLNKVMQETMGVVRNENTLLNGIQTVQALTGNLPL
                     LGMAVLKSALARKESRGAHWREDYPKSNDNDYLKTTVARFDGKQIQISFVPVPERR"
     CDS             5567..6268
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 91.4; E-value: 1.2e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_6"
                     /sec_met_domain="Fer2_3 (E-value: 4e-29, bitscore: 91.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00088, bitscore: 10.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVYKIKIRRQESQKSDSYWQEFEFDGSKNSSVANVLKELNSRTPL
                     KDNSGNIVTPISWECSCMVRKCGACAMLINERPRLACSTFLHTLKGSTITLEPLSKFPL
                     VRDLIVDRSILFENLKKLNLWLESEAYMNPWTHEPRYQSARCLMCGCCLEVCPNFSANG
                     TFAGAVAAVNAFRILNEEQESTHLNEISAEYKKKYFEGCGKSLSCHDICPIGLPVEELL
                     VRSNAAAVWGK"
     CDS             6405..6704
                     /locus_tag="ctg157_7"
                     /transl_table=11
                     /translation="MNAMDVALICKALGDANRLEIVQMLSDGEKCGCKLLERFKITQPT
                     LSHHMKILVRCGLVNDRKEGKWHHYSLNCETLMNYKHFIESLTCLGCGDGDCCK"
     CDS             6724..7041
                     /locus_tag="ctg157_8"
                     /transl_table=11
                     /translation="MKKESNSGISFFQRYLTVWVIICMLIGIMLGHFLPGMKEALNYQE
                     YAGISIPLAVLIWIMIYPMMMKVDFKSIKNIGKNPKGLFVTWIVNWLGRFRRAFVQMMK
                     Q"
     CDS             6981..7196
                     /locus_tag="ctg157_9"
                     /transl_table=11
                     /translation="MDCKLAREIPKSFCSDDETIGLVQEIYGTKVNKGICCVFRYNNLP
                     AKNVLPEYVCDYKKRAGLFQRSADLE"
     CDS             7443..9545
                     /locus_tag="ctg157_10"
                     /transl_table=11
                     /translation="MRKKKRKKHTKIITKIVLFSGILIGGEIGIVTIMNCNVPEKRLME
                     YMKYIEKGEYEQMYAMLDQKKSSMNSKEEFIERNSKIYEGIEMSDLSITDITVKRQENG
                     NAAVSYTTNMQTAAGNVEFTNDAVFSHDWTGYHLIWQDQLIFPELSATDKVQVTSEEAK
                     RGDILDRNGRQLAGEGTASSVGIVPGRMENREDTIKKLAEYLGIGADEIEDKLEAGWVK
                     ADSFVPVATIPKIQEVDLLTVNPDKTVLEEKEKQDTLLKIPGIMLSDVKVRTYYLKEVA
                     SHLVGYVQAVTAEDLQEHKGEGYRTNSVIGKTGLETLYEKELKGTDGCEICIVDANGNK
                     KSVIAYEPRKDGEDIHTTIDGDLQSTLYEQFKEDRGCSVALNPYTGEVLALVSTPSYDD
                     NDFVRGMDNSQWSALNENEDRPLYNRFRQTWCPGSTFKPVIAAIGLKVGAFTANDDFGN
                     EGLAWQKDSSWGDYTVTTLHDYEPVILKNALIYSDNIYFAKAALKIGADQLMQSLNQIG
                     FNQELPFDIKMSESQYSNMDKIETEIQLADSGYGQGQILVNPLHLASIYTAFLNDGNMI
                     KPYLHADGGSTSSEIWIKDAFSPQIVSEVMEGLEGVVNNPEGTGYGACREDIRLAGKTG
                     TAELKATKEDTSGTEIGWFTVFTTDRDTENPILLISMVENVKDIGGSGYVVEKDKAILD
                     EYLGNE"
     CDS             9586..10743
                     /locus_tag="ctg157_11"
                     /transl_table=11
                     /translation="MKKIWKIFWGVIFLAVCSGCGIKKEQKKTIEDTKEKIYRECEMLA
                     EDYQSIYENAAKENALYELSTIQKSMDYFGKYGYAVIDSYNQLDMVQSIKVDDFLKKAE
                     KEKNGKTTIFQVIAGDHFIRYDLKTKQGKIDVEVSSFKWKEDTWQETYYHEFRANSWKY
                     TENGYFFMEEYHPAGYDGPSGYRAFRVVPLNKKCRELNRKYILPFGYTLNKLFTSNWSE
                     KNYDGINFYDVFDRLLSMEEKTDEFKEGKTYEIPKESFEAIFQKYFNISAEILQTGTVF
                     HTETQTYRYRTRGIVYDFAPTPYIPYPEVVSYIENQDGTITLEVNAVWPQKELDQAFCH
                     SVTIRLLDKDRFQYVSNYVSRSEIEVTWYTERLLDEKWEECYGDN"
     CDS             10730..11434
                     /locus_tag="ctg157_12"
                     /transl_table=11
                     /translation="MEIIDMSTKRKLKKMVSVLFILGCFFIGNTKCKGADLEYISQETA
                     NYAVQERGYDLPVDEVVKEEAIEDCKNVMNQMKAIYQKADKGTSSNVVVSETVMEEMQE
                     VLKEKNVPVITSAPYSNMANYSKMEEFLFRAEQDLTGDIVLYRINRDGGIERLKFNYDG
                     TDMYLLAVKAVWGMNDNPSIVYVSYTRIEEWKYTEKGWFGYTLCVPKYPEVSEAVDGSS
                     MIRIKPLSDECR"
     CDS             11510..11977
                     /locus_tag="ctg157_13"
                     /transl_table=11
                     /translation="MEGLDYNGLYEYLYRMKYGERYEFSGNSSGIPAEEFENLIMEFLP
                     ITAEQIKKWAVFDSEHQTYDWERLGCLNYSPTYFGTSLPEVVEIRDSGEGNNVLVVDAV
                     CDTFICNDAVITSELTVKFNDDKSFKYMGNKILNNGTKEVPKYQYRIKRKN"
     CDS             complement(12005..13801)
                     /locus_tag="ctg157_14"
                     /transl_table=11
                     /translation="MSNWIIHFLISNIFICIFTLVIIGTKKLLKKYLSAATQYHLCFLL
                     FLLLAVPFFPVQIHGSQLFSWLHFFQTDSGLNSGTDTLSELTSNTQNILLNQVNDFSVS
                     ISSQFSGGLNTILFLIWITGVMIMSVLTLHSLNYVRSIKRSALPLQNQQVKTIYYNCLK
                     ELKISHPVSVYSTAFLKSPVLIGIIHPRIYIPIHLISELNPDDMRFMLLHELQHYRHKD
                     TFIGFLMVISNILYWFNPFVWYTLKEILCDREIACDSAVLQMISADEYQAYGTTLINFA
                     EKISSFSSPLAVGMSGNFRQMKRRILNIAVFRKETLYQKMRALIIYLVISAVFIGCTPI
                     LSIDASTQSVYHFSDTDKNISLLDISETFGTYDGSFVLYDNNLDSWKIYNLEEATKRIP
                     PESTYKIYDALLGLESGIITPEHSSMTWNGDAFPFPSWEADQDLNSAMQNSVNWYFQAI
                     DSQLGINRVQGFLNKIEYGNQTTSSNLDLYWSDFSLKISPLEQVTLLKKFNTNEFHLNS
                     QNVFSVKNAIKIASTPNGNFYGKTGTGRVNGQDINGWFIGYVETSDNSYYFATNIQSDS
                     NATGKKAFEITSDILKKLHIWN"
     CDS             complement(13812..14183)
                     /locus_tag="ctg157_15"
                     /transl_table=11
                     /translation="MSLPQISEAEFEVMKILWKYAPINTNEITEKLTLTTSWSPKTIQT
                     LIKRLVSKKALSYEKQGRVFVYTPLVQEDEYIRQESNSFLKRYYNGNLSSMLASYLEDD
                     KLSSTEIDNLRHLLSKHQK"
     CDS             14305..14718
                     /locus_tag="ctg157_16"
                     /transl_table=11
                     /translation="VKKIEIIERITDANGSISENILTSWEHKNQFIPEIIRFGELKIYL
                     QEQIVKKNDSDVHLSKYEYDILLLLAKSPGRIFGKEMVYDLVWNEPYSGDYNVVMRHIC
                     NIREKIEDDPGQPLYIQTVRGVGYRFNGNLGSK"
     CDS             complement(14742..16121)
                     /locus_tag="ctg157_17"
                     /transl_table=11
                     /translation="MAVTKIHGIKTTVDKAIEYICNPDKTDQNLYISSFACSPETAALD
                     FKYTLDHTHDCRDPHNTNKAFHLIQAFSPGEVSYEEAHQIGRELADRLLEGKYSYVLTT
                     HTDKGHVHNHLIFCSADNITFSHYHDCKKNYWKIRNLSDTLCQEHNLSTIMPNGKKGMK
                     YNEWAANKSESSKKTQLRKDINQTIRIVSTYSEFLTFMEAKGYEIKNAEFGENSRKYIT
                     FRSPDMSRPVRGSAKSLGKNFTKERIKERINNKLHRTTVPSVRNKLIDTNTPNIAGNIG
                     LQKWANKENLKIVSAEYNKMLTHNLHNFSELEDRIALLHMQQKEVNTSVVSLESQIRHL
                     REMLKYAKQYQKNKIYDDHYKSSKDPDRYFRKYESQIILFAGAEHILQENGMDLKHLNT
                     NKLQEQLSDLISQKKSLNTQYVSFKQEIKELELIHQNLSKYLKQDAPEIQRSSHNKLPS
                     L"
ORIGIN
        1 tgagcaagaa gcccccactt caaaatctgg gatttaagtg gtgggagcat gtcacttgta
       61 aaatttatgg ggaactaaca tcagcttatt gacataaatt taaaaataag tataataata
      121 gttgattaat tgttcaacta ttattatttg gaggtgaata tatgccaaaa acgtcttata
      181 tttgtaattg cgatgtaatt catgaggata ttgtgaatga tgtgaaatcc aagatgcagc
      241 caaaagatga ttatatccag ttggcttctt tgtttaagct atttggagat ggaactagag
      301 tacaaatctt acacgctcta gaacagagtg agatgtgtgt atgtgatctt gcagtgctac
      361 tgggggtaac aaaatctgca atttcgcatc agttaaaggc attacgcctt gcgaatctgg
      421 taaaattccg taaagaagca cagatagttt actactcgct ggcagatgat catgtgaaag
      481 agattattga caagggattt gaacatcttt ggcagaaata atatttttta acattatagt
      541 tgagtaattg aacaattaaa caaattatga ggagattagc atgaaacgca tatttctatt
      601 aaaagggttg gactgtccaa attgttccgc aaaaattgaa aaagaagtcg gagagttgga
      661 tggagtgcaa tcctcagtgg taaatctgat gaagcagacg cttacaatca atgttactca
      721 gacagccgca gatacgatag ccagtcagat tgaaacgatt gtttatagtc atgagccaga
      781 tgtggaggtt caggaagaaa caattatccc cgttacaaag agttatttgt taaagggctt
      841 ggactgtccg aactgctccg caaaaattga aaaagaagtc ggagaattgg atggagtaca
      901 atcctcagtt gtaaatttga tgaagcagac gctgacaatc aatgttgctc cagttgccgc
      961 aaatacaata gccagtcaga ttgaaacgat tgtccacagc catgagccag atgtagaagt
     1021 ttccgaaatt gcacaggaat actatatacc tgcaaaaaaa caggatacca atacatccta
     1081 taacaatgag gacaagaagt tgacgattcg tttagcgatt ggcgcagcaa tctatggtat
     1141 tggtatggca ttgacagttt ttgcgaaagt gccactgcct gtcgagttag tttttctcat
     1201 tgtctcctat attattcttg gcggggatgt tgtatggcaa gctgtgagga atatttcaaa
     1261 gggacgtgtg tttgatgaac atttcctgat gagcgtttct acgattggtg cttttgtcat
     1321 tggtgaatat ccggaagcag ttgctgttat gctgttctat caagttggtg aatttttcca
     1381 gtcattggct gttgagcgtt ccagaaaatc tatatcagat ttaatggata tacgtccgga
     1441 ttgtgctaca gtcagaagga acggagaatt gattaccata tctcctgaaa gtgttgccat
     1501 tggtgagatt attattgtaa agcctggtga aaaaatccca ttagacggtg tggtattgga
     1561 tggagattct atgctggata cgagggcttt aactggagaa tcggttccga gaagcgttca
     1621 taaaggagac gaagcacttt ccggttgtat gaatcagacg ggtgttttaa cgattaagac
     1681 aacgaaagca tttggtgaat ctactgcttc aaagattatt gatcttgtgg agaatgcgtc
     1741 cagtagaaaa gcaccaacag aaaatttcat tactacattt gcacgttatt acactcctgt
     1801 tgttgtaatc ttagcagcta ttctggcaat tctgccaccg atccttcttg gtggaggttg
     1861 gacagagtgg attcgcagag gatttgtttt ccttgtggta tcttgcccat gtgcattggt
     1921 catttcaatc ccgctgactt tcttcggagg tattggtgcg gcatctaaac gaggtgttct
     1981 tgtaaaagga agtaattatt tagaggcgct taataatgtc agcattattg tgttcgataa
     2041 aactggaaca cttacaaagg gtgttttcaa tgtgactgat attctgcctg caaatggatt
     2101 ttcaaaagaa caggttctgg agtatgcggt ccaggcagag agcttttcta accatcctat
     2161 tgcaaaatcc attctctctg cttatggaaa agaaattgac caatcagtta tctctgatta
     2221 caaggaaatt tccggatatg gaatcagtgc catggcagga aagaagaaag tttatgccgg
     2281 caatacgaaa cttatggatt cagagcatgt ggagtacaca gcctgtgaaa aagttggtac
     2341 aaaggtttat gtagcagtag atggtcaata tgccggatgc attttgataa cagatgaagt
     2401 aaagccggac agcaaaaaag caatttctga tttgaaacat atcggtgtgg aaaaaacagt
     2461 catgcttact ggtgatgatg aaaaaatcgg aaaggctgtt gcggaagaat tgcagttgga
     2521 tgaatattat gcacaactgt ttcctgatca aaaagtggaa aaggttgagc ttttagacag
     2581 taaaaagaga cagggaagca aattagcttt tgttggtgat ggtatcaatg acgctcctgt
     2641 ccttgctcgt gcggatgttg gtattgcaat gggtggtctt ggttcagatg cggccattga
     2701 agctgcggat gtggttctga tgacagatga accatctaag ctggtggatg cgattgatgt
     2761 ggcaaaagcg acaaagcaaa ttgtcatgca gaatatagtg attgcccttg gaattaagag
     2821 tgtgttcctg attcttggcg ctcttggtat tgcgggaatg tgggaagctg tatttggtga
     2881 tgtaggcgtt accataattg ctgttttgaa cgcaatgaga attttgaaaa aataggaaat
     2941 gaggtgggaa tgtgaaacga aaactgattc tgttagttgt tacgattgtt tttcttgtag
     3001 gttttggtgt catattacat tcaccgcctt ctatgattga tgcagtcaca ggagcaacac
     3061 cgaagtcaaa aaaggcggct caagcctccg cacagttgga aggctcttat gttctcggta
     3121 ttaatatgat gtcagatggt ctcgacaacg agaacacccg gaataaatta aaagaattgg
     3181 cactggacga ttcggaaaca aatgaaacag atctcatgaa aacggacatt agttttcggt
     3241 tatatgtatc tgagacggat tatccgcttg ccagttatgc taagaaactc tgtgacaggt
     3301 tgaaacaggc cggttttttc gtagatctga aagagtacag taacacaatg atgctatcaa
     3361 gagtggtaag tggaaagtat gatgtattcc tggcatcgga tgattttatt gacgttacaa
     3421 cgttatcaca gatggactat atgatcatgg acagcgaaga aatgaggtga gcgggaattt
     3481 atgagaaaat ggaatacgat tttgtctgtt ttaatgcttc tcatttttat gattcatgga
     3541 atcatgggaa gctttatgct gaacggagtt ggaagtagtg cagggaaact tcttgcatgg
     3601 attggtgttg gtattcttgt tgtgcatacg gtgattggtg tcatcctgac agttcagagt
     3661 ttacagacag cgaagcaatc cggaaaaatg tatctgaaac agaacgccat attctgggcg
     3721 agacgagcca gtgggctggc aatactgatc ctgctgttct tccatattgg cttgtttgga
     3781 aaggtgcaga atgggacata tattttgttc ccttttacaa cggtaaagat ggtaactcag
     3841 cttttgttcg tggcggcaat ctttgttcat atttttatca atatccgccc attgctcgta
     3901 tcgctgggaa tcatcagtta taaagaacga aggggtgata tttatttgat tctttcggtg
     3961 ctccttctgt ttatagcggg cgcagttatt ttctattata ttgggtggca atatctatga
     4021 gtaagacaat tattattata ggtgctggac tggcaggact ttcagcggct ttgcaggcag
     4081 cggaaaatgg atgcaatgta aaactggttt cctcccttcc gtcagagcgg gcacagtctg
     4141 ttatggcgga gggcggtatc aacgcagctt tgaatacaaa agatgaaaac gacagtcccg
     4201 aagaacattt tacagataca ataaaggcag catgtggtct ggcagatcca aatgcagttt
     4261 ggggaatgac acaggcagca ccggagctgg tgcactggct gctaaaactt ggagttaaat
     4321 ttaacatgag tggctatgat gatgtggatc tgcgaaattt tggcgggcag aaaaagaaac
     4381 ggactgcttt tgcacagagc gataccggga agcagatcat gacagctatg atagacgctg
     4441 ttcgcaggaa agaagcattt ggtatggtag aacggttcag ccatcattct ttcctaacac
     4501 ttcgtctgtg tggcaatatt tgttgtggct gcgtaatcag ggatgaatac agtcaggaga
     4561 ctgtggaatt accgggggat gcggttattg ttgccaccgg tggtatgcac ggattgtttg
     4621 gaaatacaac gggttcgctg agcaatacag gagaagtcac cgcagaattg ttccggcttg
     4681 gtgttcctct ggcaaatggc gagatgatcc agtatcatcc gacaactgtg aaatgtggtg
     4741 gaaaacgcat gctcatcagc gaggcggcca gaggggaagg tggcaggttg tttgccatga
     4801 aagatggaaa acaatggtat ttcatggagg aaaaataccc ggagcttgga aatctgatgc
     4861 cacgagatat taccgccaga gagatatgga aggtcagcca tgaatcagag gtatttcttg
     4921 acatgacgga aatatcggag gagattattt caaataagct atctggtctg gcagacgatt
     4981 gtatgaccta tctgcataaa gatatacgaa aggaaccggt gtctgtttta ccgggaattc
     5041 actattttat gggaggtatt ctggtggatg agcagcacag aacgccgatt cagaatcttt
     5101 acgctgccgg agaatgctgt gcccaatatc atggtgccaa ccgtcttggt ggaaattctc
     5161 tgttaggagc gttatacgga ggacgtgttg cggcaaaatc agcatgtgaa caggcagatg
     5221 tagtagatct atcttgtgcg acacagatag attttccacc agcgtctcaa atttcagaaa
     5281 taaagcaatt aaacaaagtg atgcaggaga ctatgggcgt tgtcagaaat gagaatacgt
     5341 tgttaaatgg gattcaaacg gtacaagcgc tgacaggaaa tcttccattg cttggcatgg
     5401 cagttctaaa gagtgctctt gcaagaaaag aaagccgtgg tgcacactgg cgggaggatt
     5461 atccgaagag caatgacaat gattacctta aaacaacggt agccagattt gatggaaagc
     5521 agatacagat ttcctttgta cctgttccag aaaggcggtg attcacttgg tatataaaat
     5581 aaaaatcagg cggcaggaga gtcagaaatc agatagttat tggcaggaat ttgagtttga
     5641 cggaagcaaa aacagctctg ttgccaatgt tctaaaggaa ttgaacagta gaaccccttt
     5701 gaaagataat tcagggaata tagttactcc catcagctgg gaatgtagct gcatggtgcg
     5761 aaaatgtggg gcttgcgcca tgctgattaa cgaacgtccg aggctggcat gctctacatt
     5821 tctacatacg ttaaaaggtt ctacaatcac cttggaacct ttaagcaaat ttccgcttgt
     5881 aagagatttg atcgttgacc ggtcaattct gtttgaaaat ttgaaaaaac tgaacctttg
     5941 gcttgaaagt gaagcttata tgaatccgtg gacacatgaa ccgagatacc agtcggcacg
     6001 ctgtctgatg tgtggctgct gccttgaagt gtgtcctaac ttctctgcaa atgggacttt
     6061 cgcaggtgct gttgctgcag tcaacgcatt tcggattctg aatgaagaac aggaaagcac
     6121 tcatttgaat gagatttctg ctgaatataa gaagaaatat tttgagggat gcgggaagtc
     6181 gttatcttgt catgatattt gtccgattgg tctgcctgtg gaagaactgc ttgtaaggtc
     6241 gaatgcagcg gctgtttggg gcaaataaaa tggatgataa aagctataat gaatgtatga
     6301 agagaatcaa aaacttgatt ctcttttttt aaaatacata cattgacaaa tatctatgta
     6361 tatattatat tgaacataga caatgatcaa tgtgaggtgt caatatgaat gcaatggatg
     6421 tggctttgat atgcaaggct ttgggcgatg cgaaccggct ggaaattgta cagatgctgt
     6481 cggatggaga aaagtgcggg tgtaaacttt tggaaagatt taaaattacc cagccaactt
     6541 tatcccatca tatgaagata ctggtaagat gcggccttgt gaatgatcgt aaggaaggaa
     6601 aatggcatca ctattctttg aattgtgaga cattgatgaa ttacaaacac tttatagaat
     6661 cccttacttg ccttggatgc ggtgacgggg attgttgtaa ataatttaag gagagcagat
     6721 atcatgaaaa aagaatcaaa ttcaggaatt agttttttcc agcgttacct gactgtatgg
     6781 gtaattatct gtatgcttat aggaattatg ttgggacatt ttcttccggg aatgaaagag
     6841 gcactgaact atcaggaata tgcaggaatt tctattccgc tggcagttct tatatggatt
     6901 atgatctatc caatgatgat gaaggttgac ttcaagagta ttaaaaatat cgggaaaaac
     6961 ccgaaaggtt tatttgttac atggattgta aactggctag ggagattccg aagagctttt
     7021 gttcagatga tgaaacaata ggattggtac aggaaatata tggaacaaaa gttaataaag
     7081 ggatttgttg cgttttccgc tataataatc tgccagcaaa gaatgtgttg cctgaatatg
     7141 tttgtgatta taagaaacga gcagggttat ttcaaagatc agcagattta gagtagttct
     7201 ttttttctga gagaaaatta aaaatcgttt ttggttcttc tggagagtga ttatagcgtt
     7261 tgggaaacat ccggagaaac cattacctca gggtgtcgtg aagttcttta tcaaagaagg
     7321 ctttgagatg ccctttcttt tttatccaaa tcttacatat ataaacctaa gaaaaagctt
     7381 gacgtttaaa tattacaagt gtaatattta agaaaatatg aaaaaaggag aaataaaact
     7441 atatgagaaa aaagaaaaga aaaaaacaca cgaagattat cacaaaaata gttttattta
     7501 gcggtatatt gattggtggt gaaatcggta ttgtaacaat aatgaattgt aatgttcctg
     7561 aaaaaagact aatggaatat atgaaatata ttgaaaaagg ggaatatgag caaatgtatg
     7621 ccatgctgga tcagaaaaaa agcagcatga acagtaagga agaatttata gaacgaaatt
     7681 ctaaaatata tgaaggcatt gagatgtctg atctgtccat aaccgatatt acagtaaaaa
     7741 gacaagaaaa cggaaatgcg gcagtttcct atacaacaaa tatgcagact gctgcaggaa
     7801 atgtagaatt taccaacgat gcggtatttt cacatgattg gacaggatat catttaatct
     7861 ggcaggatca gttgattttt ccagagttat ctgcaacgga taaagttcag gtaacgtcag
     7921 aagaggcaaa gagaggagat attttagaca gaaatggtcg tcagttggct ggagagggaa
     7981 ctgcatcttc ggtaggaatt gttccgggca ggatggagaa cagagaagat acaataaaaa
     8041 aactggcaga gtatcttgga attggagcag acgaaattga ggataagtta gaagccggtt
     8101 gggtaaaagc agattctttt gtaccagtag caacaattcc taaaatacaa gaggtcgatc
     8161 ttctgacagt gaatccggat aaaactgttc tggaagaaaa agaaaagcag gacacattat
     8221 tgaagattcc aggtattatg ttatctgatg taaaagtacg aacttattat ctaaaagaag
     8281 ttgcctctca tctggtaggg tatgtacagg cggttacagc cgaagatttg caggaacata
     8341 aaggggaagg gtatcgtaca aacagtgtga ttggaaagac tggactggaa acgctttatg
     8401 aaaaagaact aaaaggaaca gatgggtgtg aaatctgtat tgtagatgca aatggaaata
     8461 aaaaaagtgt tattgcatat gagcctagaa aagatggaga agatatccat actacgattg
     8521 atggtgatct tcaaagtact ctttatgaac aatttaaaga agacagagga tgttctgtgg
     8581 ctttgaatcc ttacacaggg gaagtattgg cgttggtaag tacgccatct tatgatgata
     8641 atgattttgt acgtggaatg gacaacagcc agtggagtgc attaaatgaa aatgaagata
     8701 ggcctttata caaccgcttt cgccagacat ggtgtcctgg ctcaactttt aaacctgtaa
     8761 ttgctgcaat tggattaaaa gtgggggcat ttactgcaaa tgacgatttt ggaaatgagg
     8821 gtctggcgtg gcagaaagat tcctcgtggg gagattatac agtgactaca cttcatgatt
     8881 atgaacctgt gatcttgaaa aatgcgctta tttattcaga taatatttat tttgcaaaag
     8941 cagcattaaa aattggtgcg gatcaactga tgcagtctct aaatcaaata ggatttaatc
     9001 aggaacttcc atttgatatt aaaatgtcag agtcccaata ttctaatatg gacaagatag
     9061 aaacagaaat ccagcttgct gacagtgggt atggacaggg acagattctg gtaaatcctt
     9121 tgcatcttgc aagcatttat acggcttttc taaatgatgg aaatatgata aagccatatc
     9181 ttcacgcgga tggtggaagc acttccagtg aaatctggat aaaagatgct ttttcaccac
     9241 aaattgtttc ggaggttatg gaggggttag agggtgtagt gaataacccg gaaggaactg
     9301 gttatggagc atgccgggaa gacattagat tagcaggaaa aaccggaaca gcggaactga
     9361 aagctacaaa agaagataca tctggaacag aaattggctg gtttacagtt tttactacag
     9421 atagagatac agagaatcct attttgctca tcagtatggt agagaatgtg aaagatattg
     9481 gaggaagcgg ttatgtggtg gaaaaggata aggcgatact ggatgaatat ctcggtaatg
     9541 aataattttt acctttaaat attacaaatg taagaggaaa atgatatgaa aaaaatttgg
     9601 aaaatatttt ggggagttat ttttcttgct gtctgtagtg gatgtggcat aaagaaagag
     9661 cagaaaaaga caattgaaga tacgaaagaa aaaatttaca gagagtgtga aatgctggca
     9721 gaagactatc agagcatata tgagaatgct gcgaaagaaa atgcactata tgagctgagt
     9781 acaatacaaa aaagtatgga ttattttgga aaatatggat atgcagtaat tgattcctac
     9841 aatcagctgg atatggttca aagtattaaa gtagatgatt ttttgaaaaa agcagaaaaa
     9901 gagaagaatg gaaaaactac tatatttcaa gttatagcag gagatcattt tattcggtat
     9961 gatctgaaaa ccaaacaggg gaaaatagac gttgaagtaa gctcttttaa atggaaagag
    10021 gatacttggc aggaaacata ttatcatgag tttagagcta attcatggaa atatacagaa
    10081 aacgggtatt tctttatgga agaatatcat ccggctggat atgatggacc gtctggatat
    10141 cgggcctttc gggtagtgcc gttaaataaa aaatgcaggg agctgaatcg aaaatatata
    10201 cttccttttg gatatacact taataaattg tttacttcta attggagtga aaaaaattat
    10261 gatggaataa atttttatga tgtttttgac cgtttacttt caatggaaga aaaaactgat
    10321 gaatttaagg aaggaaagac ttatgaaatc ccaaaagaat catttgaagc gatatttcaa
    10381 aaatatttta atataagcgc agagatactg cagacaggaa cggtatttca cacggaaaca
    10441 cagacatatc ggtatcgaac cagaggaatc gtatatgatt ttgctcccac accatatatt
    10501 ccatatccgg aagttgtttc ctacatagaa aatcaagatg gaacaataac actggaagta
    10561 aatgcggtat ggccacaaaa agaattagat caggcgtttt gtcatagcgt aaccattcgg
    10621 ctgttagata aagatagatt tcaatatgta tccaattatg tatcaaggtc agaaatagag
    10681 gttacctggt atacggaaag attattagac gaaaagtggg aggaatgtta tggagataat
    10741 tgatatgagt acaaaaagaa aactgaaaaa gatggtgagt gttttattta ttttgggatg
    10801 ctttttcata ggaaatacaa aatgtaaagg ggctgattta gaatatattt cacaggaaac
    10861 tgcgaattat gctgtacaag aaagaggata tgatttgcca gtagatgaag tcgtgaaaga
    10921 agaagctatt gaagattgta agaatgttat gaatcagatg aaagccattt atcaaaaggc
    10981 ggataaagga acttcatcga atgtagtagt ttctgagaca gtaatggaag aaatgcagga
    11041 agtattaaag gaaaaaaatg tccctgttat tacatcagcg ccgtattcaa atatggctaa
    11101 ttattctaaa atggaagaat ttcttttcag ggcagaacag gatctgacag gagatatcgt
    11161 cttatatagg attaacaggg atggtgggat agaaagactc aaattcaatt atgatgggac
    11221 agatatgtat ttgctggctg tgaaagctgt ttggggtatg aacgacaatc catctattgt
    11281 atatgtttcg tatacaagga tagaagaatg gaaatataca gaaaaaggct ggtttggtta
    11341 tacgctatgc gttccaaagt atccggaagt atcagaagcg gttgatggca gttctatgat
    11401 aagaattaaa cctttaagtg atgaatgccg gtaagtttcg aagaagtgtg tgtatttgct
    11461 tggatatcag gggaataatc ttttatgttc tgattgggat agatctgata tggaagggtt
    11521 agattataat ggtttatatg aatatttata tcgaatgaaa tacggggaga gatatgagtt
    11581 ttcaggtaac tcaagtggaa ttccggcaga agagtttgaa aatctgataa tggagttttt
    11641 gccgataaca gcggagcaaa ttaaaaaatg ggcagtattt gattcggaac atcaaactta
    11701 tgactgggaa cgattaggtt gtttaaatta tagccctact tattttggaa catctttacc
    11761 ggaggtcgtt gaaataagag atagcggaga gggaaacaat gtgctggttg ttgatgctgt
    11821 atgtgataca tttatatgta atgatgccgt tattacaagt gagctgactg ttaagttcaa
    11881 cgatgataag agttttaaat atatggggaa taaaattctg aataatggta cgaaagaagt
    11941 tcccaaatat caatatagaa taaaaagaaa gaactgataa caactatcag ccctttcata
    12001 tttgttaatt ccatatatgt aattttttta agatatcaga agtgatttca aatgcttttt
    12061 tgccagttgc attagaatca ctttggatat tggttgcaaa ataatagctg ttatcggaag
    12121 tttctacata tccgataaac cagccgttga tatcctgtcc gttgacacga ccggttccag
    12181 tttttccgta gaaattacca ttaggtgtac tggcaatttt tatagcattt ttaacagaaa
    12241 atacattttg ggaatttaga tggaattcat ttgtgttaaa ttttttcaat aatgttactt
    12301 gctctaaagg cgagattttt aatgaaaaat cggaccagta taaatccaga tttgaactgg
    12361 ttgtctggtt tccatattct attttattca aaaatccctg gactctgtta attccgagct
    12421 gcgaatcaat tgcctggaaa taccagttaa cggaattttg catagcagag tttaaatcct
    12481 gatcagcttc ccaggatgga aaaggaaagg catcaccatt ccatgtcatg gaagagtgtt
    12541 ctggtgtgat gattccggat tccaacccta ataatgcatc gtatattttg taggtagact
    12601 ctggcggaat acgtttggtg gcttcttcaa gattgtatat tttccaggaa tccaaattat
    12661 tgtcatacaa aacaaatgat ccatcatatg ttccaaatgt ttcggatata tctaacaggg
    12721 agatattttt gtctgtatca ctaaaatgat atacgctttg agtagaggca tcaatggata
    12781 aaatgggtgt acatccaata aaaacagcac taatgaccag ataaattatc aatgctctca
    12841 ttttttgata aagagtttct ttcctaaaaa cggcgatgtt gagaatacgt cgtttcatct
    12901 gcctgaaatt tccggacatt ccaactgcca gtggagagga aaaagaggat attttttctg
    12961 caaaattaat cagtgtagtt ccataagctt ggtattcatc agcagaaatc atctgcaata
    13021 cagcagaatc acaggctatt tcacggtcac agagaatttc ttttaaagtg taccaaacaa
    13081 aagggttaaa ccagtagagt atattactta tgaccatgag gaagccaata aatgtatctt
    13141 tgtgacggta atgctgtaat tcgtgtagca gcataaaacg catatcatca ggattcagtt
    13201 cggaaattaa atggatggga atgtaaattc tgggatgtat tattccgatt aaaactggtg
    13261 attttaaaaa tgcagtactg tagactgata ctgggtgaga gattttaagt tcctttaaac
    13321 aattgtaata aatagttttt acctgctgat tttgaagcgg gagagcagat ctttttatgg
    13381 aacgtacata gtttaatgaa tgaagggtga ggactgacat aatcataaca cccgttatcc
    13441 atattagaaa gagtatggta ttcaagcctc cagaaaattg actactgatg gaaactgaaa
    13501 aatcattcac ctggtttaac aaaatatttt gtgtattact ggtaagttcg gatagcgtgt
    13561 cggtaccaga gttaagtcct gagtcagttt gaaaaaaatg taaccatgaa aaaagttgtg
    13621 agccatgaat ctgtacagga aaaaatggca cggcaagtag taaaaataaa agaaaacaga
    13681 gatggtactg tgtagccgca gataaatatt ttttcagaag tttttttgtt ccgattatta
    13741 caagtgtaaa aatacatatg aagatattac tgattaaaaa gtggataatc cagttgctca
    13801 ttcaaaacct cctatttctg atgttttgat aataaatggc gtaagttatc aatttctgtt
    13861 gaagagagct tatcgtcttc aaggtaagaa gccagcatag aagaaagatt tccattataa
    13921 tatcgcttta aaaaagaatt gctttcctgg cgtatatatt catcttcttg gactaatgga
    13981 gtatagacaa atacccggcc ttgtttttcg taggaaagag cttttttgga aacaagtctc
    14041 ttgataagag tttgaattgt ttttggactc cagctggtag ttagagtaag tttttctgta
    14101 atttcatttg tattgatggg agcatatttc cataaaattt tcataacttc aaattcggct
    14161 tctgaaatct ggggtagtga cataataaaa tcctcctgct aaatcctaca tatgtaataa
    14221 atatattata ttacttgtag aagaaaaaag tcaaatggca gatgatatat agaatataaa
    14281 attaataatg tagaggcaat aaaggtgaaa aagatagaaa ttattgagag aatcacagat
    14341 gctaatggaa gcataagtga aaacatattg actagctggg aacataaaaa ccaattcata
    14401 ccggaaatta taaggtttgg agaattaaaa atatatctac aggaacaaat tgttaaaaag
    14461 aatgatagtg atgttcatct ttcaaaatat gaatatgata ttttacttct tttagcgaaa
    14521 agtccaggta gaatatttgg aaaagaaatg gtttatgatc tggtatggaa tgaaccttat
    14581 tccggtgatt ataatgtggt tatgcgacat atctgcaata tcagagaaaa aatagaagat
    14641 gatcctggac aaccattata tatacaaaca gtacgaggtg taggatatcg gtttaacggg
    14701 aatttaggca gcaagtgaaa tcgctgccta ttattatggt tttacaaaga agggagtttg
    14761 ttatgagaag atctttgtat ttcaggagca tcctgtttga gatatttgga cagattttga
    14821 tgtatcaatt ccaactcttt tatttcttgc ttaaaagaaa catattgagt atttagtgat
    14881 tttttttggg aaataagatc tgaaagttgc tcctgtaact tattggtatt aagatgcttc
    14941 aggtccatgc cattttcctg taaaatatgt tcagcaccag cgaaaagaat aatttgagat
    15001 tcatatttac ggaaataacg atccggatct ttggaacttt tataatggtc atcgtaaatt
    15061 ttatttttct gatattgttt ggcatatttt agcatttctc gaagatgacg tatctgagac
    15121 tcgagagaaa caacagaggt atttacctct ttttgctgca tatgtaacaa ggctatgcgg
    15181 tcttcaagtt ctgaaaaatt atgtagatta tgtgtgagca tcttgttata ttcagcagag
    15241 acaattttta aattttcctt atttgcccat ttctgaagtc caatgtttcc tgctatattg
    15301 ggagtgttgg tgtctattaa cttattacga acagaaggaa cagtagttct gtgaagctta
    15361 ttattaatgc gttctttgat acgttcctta gtaaagtttt ttcctaaaga tttagcactt
    15421 ccacgcactg gacgggacat atcgggagaa cgaaaggtaa tgtattttct gctgttttcg
    15481 ccaaattctg cgttttttat ttcatatcct ttagcttcca taaatgtaag aaattctgaa
    15541 taagtggaaa cgattcggat tgtctggttt atatcttttc gcagctgcgt ttttttactg
    15601 gattcagatt tatttgcagc ccattcattg tatttcattc cctttttacc atttggcata
    15661 attgtggaca ggttatgttc ctggcataaa gtgtcgctga gatttcgtat tttccagtaa
    15721 ttctttttac agtcatggta atgagaaaaa gtgatgttat ctgcagaaca gaaaattaaa
    15781 tggttatgta catgaccttt atcagtgtgt gttgtcagaa cataggagta ttttccctcc
    15841 agcaagcgat ccgcaagttc tctgccgatt tgatgggctt cttcatagga aacttcacca
    15901 ggggaaaatg cctgaatcag atgaaatgcc ttatttgtat tgtgcggatc tctgcagtca
    15961 tgtgtatgat ccaaagtgta tttaaagtca agagcggctg tttcgggaga gcaggcaaag
    16021 gaagaaatat atagattctg gtcagtttta tctggattgc agatgtattc tattgcttta
    16081 tcaacggttg ttttgatacc atggattttt gtaactgcca tattttttcc attaactcct
    16141 ttatatcgtc caggtccttt tggtaaactg tattgctact gtttatacga tgggtgatct
    16201 gattcaaatt gctgctgata ttgcccagca gggtattcat ttttcggata tgagagtagt
    16261 ctacttca
//
