LOCUS       gnlProkkaEJOCIBNC_266  14519 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EJOCIBNC_266.
ACCESSION   gnlProkkaEJOCIBNC_266
VERSION     gnlProkkaEJOCIBNC_266
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 00:46:48
            Original ID  :: gnl|Prokka|EJOCIBNC_266
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14519
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14519
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2309:5003]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2310..5003
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..14519
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14519
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             complement(2..709)
                     /locus_tag="ctg179_1"
                     /transl_table=11
                     /translation="MYLKSRVKLPDVHGKLTRLRRGDITYIKYEYDRYYDPEKKYTYPQ
                     RATIGKVCPDDDTMMIPNEAFLKYFPDAVLSGMEDRTERSSCLRVGTYAVMHKIVLDYS
                     LDKLLGQFFSERDMALLLDLASYSIVEESNVAQHYPDYAYNHPLYSSGMKIYSDASVSD
                     FFKSITKDKSTGFLNEWNAKRNRRERIYISYDSTNKNCQAGEIELAEFGHAKTDIGSAI
                     INYSVGYDLKNKEP"
     CDS             complement(1202..1432)
                     /locus_tag="ctg179_2"
                     /transl_table=11
                     /translation="METTVMNVAVSQGIWAVLAVFLLIYIVKSNEQRDTKQEEREKNYQ
                     TVIESLTEKFQILNQVQSDLKEIKDNLFNKN"
     CDS             1733..2257
                     /locus_tag="ctg179_3"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILRYISENK"
     CDS             complement(2310..5003)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     763.1; E-value: 7.2e-231)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg179_4"
                     /sec_met_domain="DUF4135 (E-value: 7.2e-94, bitscore:
                     304.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-52, bitscore:
                     168.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLKLDYLCRKNRTMFLKILILDVHRQKNFGNLKGSTPKEQYDYY
                     EKKYLNNATYVKSLLQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRK
                     FSGTVGIYMSKGDIHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGIS
                     CRTVQYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAH
                     GEYPVIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNR
                     GVLISAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYT
                     ECIIRGFCRAYMVAMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRE
                     CRKALLNVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLP
                     CTPYESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIY
                     SQIRKIVHRICSRAIIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLH
                     DFEEKNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLT
                     GKRVWMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADME
                     KDLWKKGQETGNGYGWRLKGTDGPLAGMSHGNSGFLMAYAALYECNHKAEYADKIQLLL
                     RYEDSLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLN
                     AADSLFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAK
                     ISGTEYLNLAFMNGISGTGMALMEIL"
     CDS             complement(4994..5122)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg179_5"
                     /transl_table=11
                     /translation="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYGTIVCC"
     CDS_motif       complement(5012..5122)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /locus_tag="ctg179_5_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4994..5011)
                     /prepeptide="core"
                     /locus_tag="ctg179_5_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="519.7"
                     /monoisotopic_mass="519.2"
                     /core_sequence="TIVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /leader_location="[5011:5122](-)"
     CDS             complement(5139..6620)
                     /locus_tag="ctg179_6"
                     /transl_table=11
                     /translation="MLKVLLYGLATFMETGIGVWIFSQTFSERRILEKKYYVLEWLLYS
                     LIFFGIYNFSVSLWQIDKKIEKYVIKVICIYIIGLIAGIIYDIFFVKKKEMVLRRILYI
                     GMIFWLTAQYWAGYQSLLMIILGSGIIVLYVFCYFDCTFKQAYVWNFFYAVNIGLIKEA
                     YVVYAGVFNHKQWDDFYSYPRGHTYQEVIFWILGCLFIFWIIKFILSVNSIKGILRTRL
                     KELFIIGLLEYVLLIVSIIYKFGTIKKENFVMTACLLAVSNIALIGVYVKFQKKTLEMR
                     NQILDMRCKLMEEEYEELRMSYDRYRCLVHDEKHLLLYIKECLENGELDSCITFLNHYK
                     RESIRYSGVAWTGIPEINFMLNIKVRKMEEKNIFFKVDSKIEKIPMKDIDFVVLLGNLL
                     DNAIEAAEKCEEGKGKITCIFRNINDMFIFKVKNTSIYKPYEKNTKFYTSKKEKDEHGW
                     GIESVKQIVRKYNGEIDFKYDKDFFEVEIIISDNT"
     CDS             complement(6624..7331)
                     /locus_tag="ctg179_7"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKEITEHYFAEKNIDCTVTTYQNVEWFLL
                     GLKEEKFDMYLLDIRMPGENGIEAAREIRRLYPNPVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKEKLSQAYDALLPVIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTIEKELNSKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGV"
     CDS             complement(7337..7891)
                     /locus_tag="ctg179_8"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTICEILKKTGKTREDFFPKGYLLGKRIKLTRSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKEDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             8010..8345
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.6; E-value: 4e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg179_9"
                     /transl_table=11
                     /translation="MKNNTIGKRIAEARINRNITQEHLEELSGLSVSTISRIETGKYMP
                     TIENLLKLSEILDVGLDYFLYDLLPHNKDIQSPAIQDAISIMNQMGERQTEYIVKILKI
                     YQASHQD"
     CDS             8533..9426
                     /locus_tag="ctg179_10"
                     /transl_table=11
                     /translation="MTKTEKAVTWAIRIANDPAHGYDQDNRWGPDYDCSSLVISAWQQA
                     GVPVKTKGATYTGNMKSVFLSCGFKDVTSKVNLSTGSGMKRGDVLLNIASHTVMHIGNG
                     QVVSASKNENNGYHGGKPGDQSGKEIKLQSYYNFPWDCVLRYTEDSSTTDPDPEPQPTA
                     GNAKIRKGQGYANKFANAGISITGKRDAATKKAGVKVLQTALNRDYGAGLDVDGIWGTN
                     TDNALGQHYVKNGETQYMVTAAEILLLLRAYDPNGVEIPGTFGSGLLSAVKAFQKAQGL
                     TVSGTCDRNTFLKLIS"
     CDS             complement(9572..10330)
                     /locus_tag="ctg179_11"
                     /transl_table=11
                     /translation="MKQKKIAIIMAGILAAAAAMTGCAEQNKTETQVDYTQNSQEKSEQ
                     TKQKTAEKSQPDKKQVNKSTSIGKEDSNQTADKKTKISASSNNAGDVQNSENGTDSTAG
                     TDTDDSQTTGVDTSASEDNGSTGNGGTQSDQRADQAMIYDSEGNGRLISEADDGNWYDS
                     DGNYYGSWEDIEDAMVNENGVTDQDGNKYYWTAPHDASEEVTDPYDLYSWDPGTNSYIP
                     FQAAESDCSPVGRGNGWYYYDEDSGEYVPW"
     CDS             complement(10570..13251)
                     /locus_tag="ctg179_12"
                     /transl_table=11
                     /translation="MKSNYKIFTAVFLSAIMTAAAPLTVCGAEVFSAGESFSDGTGSIP
                     AILTDMVLPGGEIGTEYQVQLEADTDVSWSLEEGSELPAGLTLSSGGVISGTPQKEGSF
                     SFTVQADNGIGVSSQELSLYVAQREQEPVIKQYELTSGTALINLGIHAEGEQSRKRLFL
                     YNAGTDSLHLSDFPQSRYFDFSYAPIFDTNTDEEMQPGSCAAVDIDDKKNLPAGNYEET
                     VTFETKEGASCKVTLKVIVGASSEKDYELSIETGTEEEFTESDFYDPEFRVEKYVVVRN
                     SGKKETRIRIDTSGLKNFEVDDQMAKWTEDYEEQDSKKLLKPGETLYFYILPKQEYGIY
                     DETFAFLADDGSRYPLHVTMNREKNPTEKKQLEITEKSAGGFPTMQWGYKTLPEAKTYI
                     LKNVTDTDMKLSFNRSKECSVLLSGNAYLAPGESTELRLWPKLGLSVGKYSFQVTVTAK
                     TVAGEHLTTQNLYNSFIVGDRTYQGLADAVAPVTGITNGAEKTADALHLPKSLEVYGAE
                     VNGEKTTFSASVKWDVENCAYDPKSKAAQSFLVNGSLELNEDENNEGLDTAVQIMVQVD
                     AYQTLNRPVIDTRWTRVITNYAMLYLRDLSNEADGYQFVTAKSQKDLKKGNYTAQTKIT
                     NSELNQYPELKYIPEGTHSLYCRAYKENSSHVMEYGEWSDGVPVTVKAKTPDAPVVQKV
                     QVKKNDVRIVLNSKGEEPDGYDVVAARSKNGKEPSDYIKVKSGYSGSSKELILRGVPAG
                     TWYIGVHAYKYLNGSNTKVLSKWAEVRKVTVKTSLVTGKPAVKSAKVSRQGTKRNVAVT
                     FTVPKSCDGTDWVLAKKVSKSDNGSYTGVSSYAYTKKNQTKTTVVFKNVKPGVYYLAGR
                     AYVKGYAKSYTKWSKIKKIVVK"
     CDS             complement(13446..14414)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 214.8; E-value: 3.4e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg179_13"
                     /transl_table=11
                     /translation="MKLGILGAGGIASTMAKTVAGMKDVEAYAVAARDLERARVFAQKY
                     EVKKAYGSYEEMLADDEVGLVYIATPHSHHYLHAKMCLEAGKHVLCEKAFTVNAEQAQK
                     LFDLAKEKKLLITEAIWTRYMPSRKMINDIIESGVIGEVTAVTANLSYTVSHVERIRKP
                     ELAGGALLDVGVYPINFASMVLGDKVKDVKATAIFQNGVDILDSIAMVFEGDRMATLQC
                     GAREISDRMGSIFGTRGYMQVQNINNPEKITVFDTEHKEVASYVVPEQISGYEYEVESC
                     MKAIHEGKTECPEMPHAETIRIMKIMDDIRKSWNYEIPCIE"
ORIGIN
        1 gtggttcttt attcttaaga tcatatccaa ccgaatagtt gatgatagct gaaccgatat
       61 ctgtcttggc atgaccgaat tcagccagtt caatctctcc ggcctgacag ttcttattcg
      121 tagaatcata ggaaatataa atacgctccc ttcgatttct ctttgcattc cattcattca
      181 gaaagcctgt actcttatcc ttggtgatgc tcttaaagaa atcacttacc gacgcatcac
      241 tatagatctt cataccagaa ctatacagtg gatgattgta tgcgtaatcc ggataatgct
      301 gtgccacatt gctttcttct acaatagagt aagaggcaag gtcaagcaat aatgccatat
      361 cccgctcaga gaagaactgt ccgagcagct tgtctaacga ataatccaat actattttat
      421 gcattacagc atatgtacca acccgcagac agctgctacg ttctgtccgg tcttccatcc
      481 ctgataagac tgcatctgga aagtatttca gaaaggcttc gttaggaatc atcatagtgt
      541 catcatctgg acataccttg cctatagtcg ctctctgtgg ataggtatat tttttctccg
      601 gatcataata gcgatcatac tcatacttaa tatatgtgat atccccgcgt cttaatcggg
      661 tcaattttcc atgcacatcc ggtagcttaa ctcttgattt caggtacata tttgcctcct
      721 ttattcaggt ttatatagcc ctaaatttat tgtacagcac aacccgtatt tttgcaataa
      781 tttccgcaga aatacgggct tttttaaaat tttattttcg ttagggctac tcatttttgg
      841 aagttaagga gaaataaaaa aattttggca aaagcaaaaa agtagaaaaa acaccatgaa
      901 aaaatgacaa aacatagaag ccgcaatcca gcataaacac ttggattgcg gccttttttt
      961 taatctattt tacactaccc aaaagtcagg ttttattatc ataatatacc atttactata
     1021 cgaacatctg taaatctggg attaaaagta ttctaatgga cacgaatgtt atgcttatat
     1081 tcatctacca ttttagtaaa catatttttc tcaaattaac ctattttctt acctaaaatg
     1141 acagaagccc tctccgctgg aaaaatatat cctgcagaaa aggctttttt cttttcccta
     1201 tttaattttt gttaaaaaga ttatccttaa tctctttcag atcgctttga acctgattca
     1261 gaatctgaaa tttctcagtt aaactctcaa tcaccgtctg gtaatttttc tctcgttctt
     1321 cctgctttgt atccctctgt tcatttgatt tcacaatgta aatcagaaga aaaaccgcaa
     1381 gcacagccca gattccctgt gaaactgcca cattcataac cgttgtttcc atggtttctg
     1441 cctccttcct taatcttctt ttattatgca aactttttct atgttttgtc tactaaaagt
     1501 cttttctaat cttattatta ccgttttaat ttaaagcata tttctattct ctacaattat
     1561 tttgcaaatc tctttttacc atgtatttct tctcctatcg ctgatctaaa tttgcaacct
     1621 cacttaataa agagtttttt ctcttccatt tgtaaactca caaatttttt tcttttttag
     1681 tttctgatca gcagttttct tactacttcc cctaaaaagg aggtagatac ctatgaaaac
     1741 actgacagaa cttatccaaa attatcaaaa tggtatccca gattcagaca gtgaaattct
     1801 caaacgtatg gaaccgcttg tgaaaggata tgcatcccgg attcactgca tggaacgtga
     1861 agattccaca caggaattgt atcttactct gttaaagaca ttgccatatt taagttcttc
     1921 atcctcagaa ggtgaatgta tcagatacat gcagacctct gtcgaaaaca gatatcgttc
     1981 cctttgccgc agttgtcttt ccgaacctga aaaagatgat tttgattctt gttctgtttc
     2041 attacaggct cccgacagtt ttgatgacac ctattatgat gtaaccgcat atatcaactc
     2101 ttacccttcg gacagtgtcc agagaaaaat tctgtccatg tacttttatc aggataaaag
     2161 cgatgcccag attgcccgga aactgaagct gtcccgccag tacgtcaatc ggatgaagaa
     2221 gaaactaatt ctcagatata tttccgaaaa caaataaaag aaacacctgc tgaccataaa
     2281 tttacagtct gcaggtgttc ccttagtttt cataaaattt ccattaatgc cattcccgta
     2341 ccggaaatgc cattcataaa agccagattc agatattctg tcccagatat ttttgccggg
     2401 tgatccagtt gaaataaaag gcagtcacat aacgcctcat attgctcctt cattttttta
     2461 ttaccatatt ttcgaaggta cttcttcata ataagtaaat tcccggacat cccatgacac
     2521 agacaaattt tttcatcctg ttctccataa aacaaagagt ctgcagcatt taacctgtct
     2581 tttttaatct gcatatcctc aggaaacagc tcttccagtt tcattcgtga aagcaggatt
     2641 cccggcgccc catggcacca tgcattcatg aagctttccc ctgaactctc tcgtaaatcc
     2701 ttccagtttc cggctttctc tgagtacaga gaatcctcat atctcagcaa aagctgtatt
     2761 ttatcagcat attccgcttt atgattacat tcatacaacg ctgcataagc catcagaaat
     2821 ccactgttgc catgagacat tccagccagc ggtccgtctg ttccttttaa tctccatccg
     2881 tatccatttc cggtttcctg tcctttcttc cacaaatctt tttccatatc tgccgctatt
     2941 tcataatatt tcagatttcc ggtttcttta tataacatca ctgccactac aatagctccg
     3001 gcatttccgc tcagataatc cagttgtgaa tcttctttcc ataccctctc aataatgctg
     3061 aaatgctttt ccgcataaat catccacact ctttttcctg taagtttaaa cagataaaga
     3121 taggtatata ccaccgagct ttctccattt acaatacctg tcagaagatt tttatcataa
     3181 atctgttttt tgtgtatttc atctgtataa gctttcaatc tcaaaacagc aagatgataa
     3241 atttcttctg cacttgcatt cttttcttca aaatcatgaa gatattttgc aagaaacaag
     3301 actatcccgg atattccatc atataaatag attccacctg atctgagatt ccagtgacca
     3361 ttatcccaga attgcagacc cgcccagccg gcgctctgtt cccggataat tgctctgctg
     3421 cagattcgat gaactatctt tctgatctga ctgtatattt tgcgctcttt atctgtgtca
     3481 tatcccttta tcctggtcgg aaacatcttt ttctttccat cagatgcctt cagcatttcc
     3541 atggacagcc tgatataatc acactgacat tccatatcag agtaactcat ctgcttcata
     3601 tgcattcgcc atgactcata aggagtacag ggcagatatt ctttatgttc tccgccattt
     3661 ccatcataaa cagatctgct gttcgcatca atctcaaagc agggtatatc catttccaga
     3721 aggctgtcaa tttcataatc atgaatctct ttcataaaag aagattcccc ctctttgtga
     3781 atcacattca aaagagcttt cctgcattct cttgacttca tataatccgg atgaaacgaa
     3841 gccataagat acattgcata ctgttgggta tgccgcagta caactctgga acgtccgtca
     3901 aaaaagccgg acaacatcac ctccactttc ttatctgcca ttgccaccat gtacgctctg
     3961 caaaatcctc tgataatgca ttccgtataa tctgccgcat tgataacctg atcatttagt
     4021 cttacaatgc attcctttat ctgcatttcc acaggttcat attctatgtg gatatcagat
     4081 gttttatcat cctttaccac aggaagttta aacggtgttt ttatcttttc ctctgttccc
     4141 attgcactta taagaactcc tctgtttcct ctgccccatg tgagaacagg aagcattcct
     4201 gtatgtataa ccgaatttgc caattttatc tctgtacttt tgtttatttt ttcttctaca
     4261 ctacttccgt ctttctctga ttgttgtttt aaatatcccg gatatgtctc catatcgata
     4321 atcacaggat attctccatg tgcaataata ttttcaccat gaagatctgt tgctccgagg
     4381 gcatatccca aaaacagatg tatgcccatt ctgaaataat aatgctccac ctcactttcg
     4441 tttttacagg gaatattctc aattttttct tcccatccat aggaatcatg agataaatat
     4501 tgtaccgtcc tgcaggaaat tcctgttttt ctgcataaat agttataaag ttcctgatat
     4561 tttatattct tatcaagact atgtggctta tagtacagaa ttgttccatt atccaattct
     4621 accttcgcca cacttcgtcc tcctctgtgt atatcgcctt tcgacatgta aattcccaca
     4681 gtcccggaaa actttcttcc atcacagaat attttttgta tctgttcttt ttctgcataa
     4741 agagatttcc tgatttcaca ttctgctctc tggatagagt tatttttcaa ttcaagcaga
     4801 cgttttaact cgggatattc ctgcagtaaa gattttacat atgttgcatt gttaagatat
     4861 tttttttcat aataatcata ttgttctttt ggcgtacttc cttttagatt tccaaaattt
     4921 ttctgccgat gtacatctaa gattaatatt ttaagaaaca tagttcgatt ttttctgcat
     4981 aaataatcca atttcagcaa cacactatag ttccatatac aataaaagac aatttctctt
     5041 ctatactttc cgtatctatt atctctattt catctaattc tttttccaca tttcctatta
     5101 ttttatcatt catttcgttc ataaccgtca ctctcccatt atgtattatc gctaattatt
     5161 atttctactt caaaaaaatc tttatcatat ttaaaatcta tttcaccatt atactttctt
     5221 acaatttgtt tgacactttc aatcccccat ccgtgctcat ctttctcttt tttacttgta
     5281 taaaatttag tgtttttttc ataaggttta tatatgcttg tattctttac tttaaaaata
     5341 aacatatcat taatatttcg aaaaatacac gtaattttac cttttccctc ttcacacttt
     5401 tcagcagctt ctattgcatt atccaaaaga tttcctagga gtacaacaaa atctatgtct
     5461 ttcatcggaa ttttttctat ttttgaatct actttaaaaa aaatattctt ttcttccatt
     5521 tttcgcactt ttatattcaa cataaaattt atttctggaa ttcctgtcca cgctactcca
     5581 ctatatctaa tgctttctct cttgtaatga ttcaaaaaag taatacatga atccagttct
     5641 ccattttcca ggcattcttt tatatataaa agcaaatgtt tttcatcgtg caccaaacac
     5701 cgataccggt catatgacat tctcaattct tcatattctt cttccattaa tttgcatctc
     5761 atatctaaaa tctgatttct catttctagg gtcttttttt gaaacttaac atatacacca
     5821 atcaatgcta tattactaac tgctaataaa catgcggtca ttacaaaatt ttccttttta
     5881 atcgtaccaa atttgtatat gatgctaact attaataaaa catactctaa caatccaata
     5941 ataaaaagtt ccttcagacg tgtacgcaat attcctttta tactgtttac tgacaaaata
     6001 aatttaatta tccaaaatat gaataaacag cctaaaatcc aaaatataac ttcctgatat
     6061 gtatgtcctc tcggatatga ataaaaatca tcccactgtt tatggttaaa cacccctgca
     6121 tatacaacat aagcctcttt tatcaatcct atattaactg catagaaaaa attccaaaca
     6181 tatgcctgtt taaatgtgca atcaaagtag caaaaaacat ataatacaat tattccactc
     6241 ccaagaataa tcattaacaa cgattgatat ccagcccaat actgagcagt taaccaaaat
     6301 atcatgccga tatataatat tcttcttaag accatctcct ttttctttac aaaaaaaata
     6361 tcatatataa ttcctgcaat taatccaatt atgtatatac aaataacttt tatgacatat
     6421 ttttctattt ttttatcaat ctgccataat gaaacagaaa aattataaat tccaaaaaaa
     6481 atcaaagaat acaacagcca ttctagaaca taatattttt tttctaatat tcttcgttca
     6541 gaaaacgtct ggctaaatat ccagacacct atccctgtct ccataaacgt tgccagtcca
     6601 tacaataaaa ctttcagcat tcttcatacc ccccagtaat tcagaattgc ttctctgaca
     6661 cctttgaatc tttctctgcc aactgtaata atattaccgt cccgcatata aagatccctt
     6721 cctttcatct tcatcacatg ttggatgttt gcaagatatc ctctgtcaga tataataaat
     6781 tcttttgaat tcagttcttt ttctattgtt gacagacttg ctctgatctt tacttcccca
     6841 cgcctgtgca caaaaatcac atattttcct tcttttttca tatagaaaat atcagaatat
     6901 gccagttttt caacttcgtt tcttttattt atgatatagt accgctcttc tttctccata
     6961 attacaggaa gaagcgcatc ataagcctgc gaaagttttt ccttcagaca ctctttgggg
     7021 atataacgat aggtgtttac ctcatatgct tctattgcat aatccacaaa atttgtaata
     7081 aatataataa ccggattcgg ataaagtctg cgtatctctc ttgctgcctc tattccgttt
     7141 tctcccggca tccggatatc cagaagatac atatcgaatt tttcttcctt caatcccagc
     7201 agaaaccatt ccacattctg gtatgtcgtt accgtacaat ctatattttt ctctgcaaaa
     7261 tagtgttctg taatctcctt ttcttttttc agatacattt cgtcatcatc cagaatcatt
     7321 attcttatca tagcaattat tcctccatga atgtataaaa tctgaatttc ttcacatcat
     7381 aaaaataact ttcatcctta ttgatgacca gctcataaac ctcgatatcc tctttggttg
     7441 tcacatcagt tctgtgatac tgataaatgt atctgccttc ctcatgattt tttacctttc
     7501 tgatgatatc atccaccaat tctccgattg tcatcggact gtctctggaa ggtctccatc
     7561 ttccaatcat accacgaacc tgtgatctgg tcagtttaat tctctttcca agaagatatc
     7621 ctttcgggaa aaagtcttct ctggtctttc ctgtcttttt caatatctca catatcgtct
     7681 tattttcttc atctaaagca aatcccatat tagcataagc ctgcatatga agcaacgcta
     7741 attcgagata tttactgttt tcagattctt tattccataa cagtaatttg tccagacttt
     7801 tatatacagt ttctctgatt gtaattccct gattttgcaa agtctgcaaa gaaaacatca
     7861 tggtatacaa atcctttgta tattcgtcca tattcctata ttcctcctgt cataaaacat
     7921 atcaaatttg attagtcact tgtcatttat atccttatac atatttaatt ccgtctgtta
     7981 aactttatca aaggaaagga tttttattta tgaaaaacaa tactatcgga aaaagaattg
     8041 cagaagctcg gatcaacagg aatattaccc aggaacacct ggaagaatta agtggtttat
     8101 ctgtaagtac gatcagccgg attgaaacag gtaagtatat gcctactatc gaaaatctcc
     8161 ttaagctttc tgaaattctt gatgtgggac ttgactattt tctttatgat ctgcttcctc
     8221 ataataaaga tattcaaagc ccggctattc aggatgcgat ttcaatcatg aatcaaatgg
     8281 gtgaacgcca gactgaatac attgtaaaaa tactgaaaat atatcaggcc tctcatcagg
     8341 attaaatata attacaattc gacaattttc gtgtttttgt cctcgaaaag catttttctg
     8401 acctcgaagc aacaatcagg aaatgctttt tatttttttc tgtttcatgt ttacattttt
     8461 cccttttctc actctttata agatgtatca ccggtgagca aataaataat caaatttcag
     8521 gaggatgaaa aaatgacaaa aacagaaaaa gcagtaacat gggcaattag aatcgcaaac
     8581 gatccggcac acggatatga tcaggataac agatggggac cggactacga ttgttcttca
     8641 ctggtaatct ccgcatggca gcaggctggt gttcctgtaa aaacaaaagg agccacttat
     8701 acaggaaata tgaaatccgt ttttctgtcc tgcggcttta aggatgtaac ttccaaagtt
     8761 aatctcagca caggaagtgg catgaaacgt ggcgatgtat tattaaacat cgcaagtcat
     8821 acagtaatgc acattggtaa tggtcaggtg gtatctgcca gcaaaaatga aaataatgga
     8881 tatcatggtg gtaaacccgg agatcagagc ggaaaagaga tcaaacttca gagttattac
     8941 aatttcccct gggattgcgt tctccgttat actgaagatt cttcaactac tgatcctgat
     9001 cctgaacctc agccaactgc aggaaatgca aaaatccgca aaggtcaggg ttatgccaat
     9061 aaattcgcca atgcaggaat ctctattacc ggaaaaagag acgctgctac caaaaaagca
     9121 ggcgttaaag ttcttcagac agctctgaac agggattatg gtgccggtct ggatgtagac
     9181 ggtatctggg gaacaaacac agacaatgct cttggacagc attatgtaaa aaatggtgaa
     9241 acacagtata tggtaactgc cgctgagatt ctccttcttt tacgtgctta tgatccaaac
     9301 ggtgtagaga ttcccggtac ctttggctca ggacttctct ctgctgtaaa ggcattccag
     9361 aaggcacagg gcttaacagt ttccggaacc tgtgacagaa atactttcct gaaactgatc
     9421 agctgatctt taccagataa acatccggca gaattctgtc ccctgattct gtcggatata
     9481 ccccttcact attcatgtat ataacaaaaa gaagcaattt tgaaacccat taaaatggtc
     9541 tcaaaactgc ttcttttcgc atttttatat tctaccacgg aacatattcg ccgctgtctt
     9601 catcataata ataccagccg tttcctctgc ctacaggact acagtcagat tccgcagcct
     9661 gaaacggtat ataggaattg gttcccggat cccaggaata caggtcatac ggatctgtga
     9721 cctcttctga tgcatcgtga ggtgctgtcc agtaatattt attgccatcc tgatctgtga
     9781 caccattttc atttaccata gcatcttcaa tatcttccca gcttccatag taatttccgt
     9841 cactgtcata ccagtttcca tcatcagctt cagaaatcag ccttccattt ccctcactgt
     9901 catatatcat tgcctgatct gccctctgat cagattgagt accaccatta cctgttgaac
     9961 cattatcttc agatgcagaa gtgtccaccc ctgtggtctg ggaatcgtct gtatcagttc
    10021 ccgcagtact gtctgttcca ttctctgaat tctgtacgtc gcctgcatta ttggatgaag
    10081 cagatatttt cgtcttctta tccgcagtct gatttgaatc ttcttttcca atggatgtac
    10141 ttttatttac ctgtttttta tccggctgag atttttctgc tgttttttgt tttgtctgtt
    10201 cggatttctc ctgtgagttc tgcgtataat caacctgtgt ctctgtttta ttctgttccg
    10261 cacagccagt catagcagcc gctgctgcta aaatccctgc cataataatt gcaatctttt
    10321 tctgcttcat tttgttatcc tttctacatt tgttaaaaat gtcgatgcct ttatcataat
    10381 gtgcttttcc tgttcattat gacatacttc acaggcttcg atgcctcata tgtcccttat
    10441 ctgtcatgaa atgtacccca tttttttcca aaatctttac cccataattt tgccttataa
    10501 acgcttggta aaaggggaat atcttttttc ttaaaagtga aatctctgtg aaacaaatgg
    10561 cagcagtact tatttcacaa ctattttctt tattttcgac catttcgtat aactttttgc
    10621 ataacctttt acataggcac gtcctgcaag gtagtagact ccgggcttca catttttaaa
    10681 gaccaccgtg gtttttgtct gatttttctt tgtgtaagca taactgctta caccagtata
    10741 gctgccatta tcagatttgg aaactttctt tgccagtacc cagtctgttc catcacagga
    10801 ctttggaaca gtaaacgtca ccgccacgtt tctttttgtt ccctgtctgg aaaccttagc
    10861 tgatttaaca gcaggttttc ctgttacaag gcttgttttt acagttacct tcctgacctc
    10921 tgcccattta ctgagcactt tggtattgct cccattcaga tatttataag catgtacgcc
    10981 aatataccac gttcctgccg gtacgccccg taagataagc tctttactgc ttccggaata
    11041 cccactcttt acctttatat aatccgatgg ttcttttccg ttcttacttc tggcagcaac
    11101 aacatcgtaa ccgtccggtt cctcaccctt gctgttaagt actattctga catcattttt
    11161 cttcacctgc accttctgaa ccacaggtgc gtccggagtc tttgccttta ccgtaaccgg
    11221 aaccccgtct gaccattccc catattccat aacatggctg ctgttctctt tgtatgccct
    11281 gcaataaaga ctatgtgttc cctccggaat atacttcagc tcaggatatt gattcagttc
    11341 agaatttgta atttttgtct gcgcagtata attccccttt ttcagatcct tctgagattt
    11401 cgctgtcaca aactgatagc cgtccgcttc attggaaaga tctctcagat aaagcattgc
    11461 ataatttgtg atcactctgg tccaccgcgt atcaataact ggtctgttta atgtctgata
    11521 agcatccacc tgtaccatta tctgtacggc agtgtccagc ccttcattat tttcatcctc
    11581 attcagttcc agagatccgt tgaccagaaa actttgagct gccttgcttt tcggatcata
    11641 agcacaattc tccacatccc acttcacaga cgcagaaaat gttgttttct ctccattcac
    11701 ctcggcgcca tagacttcca gcgacttcgg cagatgcaaa gcatcagcag ttttttctgc
    11761 accattggta attccggtca caggcgcaac agcatctgcc agtccctgat aagtccggtc
    11821 tcctacaata aaagaattat acagattctg cgttgtcagg tgttctcctg ccactgtttt
    11881 cgcagtcaca gtcacctgaa aactatattt tcccaccgaa agccccagtt tgggccagag
    11941 tctcagttct gtgctctccc caggtgccag ataagcattt ccagataata acacactaca
    12001 ttctttacta cggttaaaag acagcttcat atctgtatca gtaacatttt tcagaatata
    12061 tgtctttgct tccggaagtg tcttatagcc ccactgcatt gtcggaaaac ccccggcaga
    12121 cttttcagta atttccagct gcttcttttc tgtcggattc ttctctctgt tcattgtaac
    12181 atgaagagga tatctgcttc cgtcatctgc gagaaatgca aacgtttcat cataaattcc
    12241 gtattcctgc ttcggcaata tataaaaata aagcgtttct cccggtttca gcagcttttt
    12301 ggaatcctgt tcctcataat cttctgtcca ctttgccatc tggtcatcca cttcaaaatt
    12361 cttaagacca gaagtatcta tccgtattct ggtttccttt tttcctgaat ttctgaccac
    12421 tacatacttc tccacacgaa attccgggtc atagaaatcg ctttctgtaa attcttcttc
    12481 tgtacctgtt tctatactca gctcataatc tttttcagag gaagctccca caattacttt
    12541 cagagtaacc ttacaggaag caccctcttt tgtctcaaat gtcactgtct cttcataatt
    12601 tccggcaggc agattcttct tatcatcaat gtccacagcc gcacaacttc cgggctgcat
    12661 ttcttcatcc gtatttgtat cgaaaatcgg tgcgtaggaa aaatcaaaat atctgctctg
    12721 cggaaaatca gagagatgaa gcgaatctgt tcctgcatta taaagaaata accgcttacg
    12781 tgactgttct ccctctgcat gaattcccag attgatcaaa gcagtacctg atgtcagctc
    12841 atactgcttt ataacaggtt cctgctcacg ctgtgcaaca taaaggctca gttcctgtga
    12901 agaaactcca ataccattgt ccgcctgtac agtaaagctg aaactccctt ccttctgcgg
    12961 tgttccgctg atcactcccc cggaagacaa cgtaagtccc gccggaagct cgcttccctc
    13021 ctccagactc cagctcacat ctgtatcagc ttcaagctgt acctgatatt ctgttccaat
    13081 ctctccaccc ggcagaacca tatctgtcaa tatggcagga atactccctg ttccatcact
    13141 gaaagattct cccgccgaaa aaacttccgc cccgcatact gttaacggag ctgctgctgt
    13201 cataattgcc gataaaaaaa ctgctgtaaa aattttgtaa ttacttttca ttcttctcct
    13261 ccagataata aaatataaaa gtatcaattt acctaattaa tattaatata ccactggacg
    13321 ggaatgtttc tgtaattacg gaatgacatg ttgtataatg gtcatgaata tcagaaaagc
    13381 cagtaatgtt tcgggtatat gtcaaaaaca ttactggtct tttttataag attattccac
    13441 actttttatt cgatacaggg aatctcataa ttccaggatt tacggatgtc gtccatgatt
    13501 ttcatgatcc ttattgtttc cgcatgaggc atttccggac actccgtttt tccctcatga
    13561 attgctttca tgcaggattc tacctcatat tcatatcctg agatctgttc cggcacaaca
    13621 taagaagcca cttctttatg ttcggtatca aacactgtaa tcttttccgg attattgata
    13681 ttctgcacct gcatatatcc tctggttccg aaaatacttc ccattctgtc tgagatttct
    13741 cttgctccac actgaagggt tgccatgcgg tctccctcaa acaccatggc aatgctgtcc
    13801 agaatatcca ctccattctg aaagattgca gtagccttta catcctttac cttatcgcca
    13861 agcaccatgg aggcaaaatt gatcggatat acgcctacat ccagaagagc acctcctgca
    13921 agctccggtt tacggatacg ttccacatga cttactgtat agctgagatt cgcggtaact
    13981 gccgtaactt ctccgatcac accactttca ataatatcgt tgatcatctt tctggacggc
    14041 atatatcttg tccagattgc ttctgtgatc agaagctttt tctcttttgc aaggtcaaat
    14101 aatttttgtg cctgctctgc atttacagta aatgcctttt cacaaagcac atgctttccc
    14161 gcttccagac acattttcgc atgcagataa tggtgtgaat gaggagttgc gatataaacc
    14221 agtccaacct catcatctgc cagcatttcc tcataggatc catatgcttt ttttacttca
    14281 tatttctgtg caaatacccg ggcacgttcc agatcacgag cagcaaccgc atacgcctcc
    14341 acatctttca ttcctgccac tgttttcgcc atagtagaag caatgcctcc tgctcccaga
    14401 atacctaact tcattttact gtccgttact gaaaacttat aaaaagttat aaacttctat
    14461 gtttcattcc tacttcaacg agtatgcttt tgatgatata aatatcaatc tactcacaa
//
