LOCUS       c00178_gnlPro..        14748 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EJOCIBNC_264.
ACCESSION   c00178_gnlPro..
VERSION     c00178_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 03:59:24
            Original ID  :: gnl|Prokka|EJOCIBNC_264
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14748
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14748
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4016:6268]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4017..6268
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14748
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14748
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             162..521
                     /locus_tag="ctg178_1"
                     /transl_table=11
                     /translation="MPKTSYICNCDVIHEDIVNDVKSKMQPKDDYIQLASLFKLFGDGT
                     RVQILHALEQSEMCVCDLAVLLGVTKSAISHQLKALRLANLVKFRKEAQIVYYSLADDH
                     VKEIIDKGFEHLWQK"
     CDS             581..2935
                     /locus_tag="ctg178_2"
                     /transl_table=11
                     /translation="MKRIFLLKGLDCPNCSAKIEKEVGELDGVQSSVVNLMKQTLTINV
                     TQTAADTIASQIETIVYSHEPDVEVQEETIIPVTKSYLLKGLDCPNCSAKIEKEVGELD
                     GVQSSVVNLMKQTLTINVAPVAANTIASQIETIVHSHEPDVEVSEIAQEYYIPAKKQDT
                     NTSYNNEDKKLTIRLAIGAAIYGIGMALTVFAKVPLPVELVFLIVSYIILGGDVVWQAV
                     RNISKGRVFDEHFLMSVSTIGAFVIGEYPEAVAVMLFYQVGEFFQSLAVERSRKSISDL
                     MDIRPDCATVRRNGELITISPESVAIGEIIIVKPGEKIPLDGVVLDGDSMLDTRALTGE
                     SVPRSVHKGDEALSGCMNQTGVLTIKTTKAFGESTASKIIDLVENASSRKAPTENFITT
                     FARYYTPVVVILAAILAILPPILLGGGWTEWIRRGFVFLVVSCPCALVISIPLTFFGGI
                     GAASKRGVLVKGSNYLEALNNVSIIVFDKTGTLTKGVFNVTDILPANGFSKEQVLEYAV
                     QAESFSNHPIAKSILSAYGKEIDQSVISDYKEISGYGISAMAGKKKVYAGNTKLMDSEH
                     VEYTACEKVGTKVYVAVDGQYAGCILITDEVKPDSKKAISDLKHIGVEKTVMLTGDDEK
                     IGKAVAEELQLDEYYAQLFPDQKVEKVELLDSKKRQGSKLAFVGDGINDAPVLARADVG
                     IAMGGLGSDAAIEAADVVLMTDEPSKLVDAIDVAKATKQIVMQNIVIALGIKSVFLILG
                     ALGIAGMWEAVFGDVGVTIIAVLNAMRILKK"
     CDS             2952..3470
                     /locus_tag="ctg178_3"
                     /transl_table=11
                     /translation="VKRKLILLVVTIVFLVGFGVILHSPPSMIDAVTGATPKSKKAAQA
                     SAQLEGSYVLGINMMSDGLDNENTRNKLKELALDDSETNETDLMKTDISFRLYVSETDY
                     PLASYAKKLCDRLKQAGFFVDLKEYSNTMMLSRVVSGKYDVFLASDDFIDVTTLSQMDY
                     MIMDSEEMR"
     CDS             3481..4020
                     /locus_tag="ctg178_4"
                     /transl_table=11
                     /translation="MRKWNTILSVLMLLIFMIHGIMGSFMLNGVGSSAGKLLAWIGVGI
                     LVVHTVIGVILTVQSLQTAKQSGKMYLKQNAIFWARRASGLAILILLFFHIGLFGKVQN
                     GTYILFPFTTVKMVTQLLFVAAIFVHIFINIRPLLVSLGIISYKERRGDIYLILSVLLL
                     FIAGAVIFYYIGWQYL"
     CDS             4017..5561
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 269.9; E-value:
                     1.4e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg178_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.6e-83, bitscore:
                     269.9, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.4e-17,
                     bitscore: 52.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTIIIIGAGLAGLSAALQAAENGCNVKLVSSLPSERAQSVMAE
                     GGINAALNTKDENDSPEEHFTDTIKAACGLADPNAVWGMTQAAPELVHWLLKLGVKFNM
                     SGYDDVDLRNFGGQKKKRTAFAQSDTGKQIMTAMIDAVRRKEAFGMVERFSHHSFLTLR
                     LCGNICCGCVIRDEYSQETVELPGDAVIVATGGMHGLFGNTTGSLSNTGEVTAELFRLG
                     VPLANGEMIQYHPTTVKCGGKRMLISEAARGEGGRLFAMKDGKQWYFMEEKYPELGNLM
                     PRDITAREIWKVSHESEVFLDMTEISEEIISNKLSGLADDCMTYLHKDIRKEPVSVLPG
                     IHYFMGGILVDEQHRTPIQNLYAAGECCAQYHGANRLGGNSLLGALYGGRVAAKSACEQ
                     ADVVDLSCATQIDFPPASQISEIKQLNKVMQETMGVVRNENTLLNGIQTVQALTGNLPL
                     LGMAVLKSALARKESRGAHWREDYPKSNDNDYLKTTVARFDGKQIQISFVPVPERR"
     CDS             5567..6268
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 91.4; E-value: 1.2e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg178_6"
                     /sec_met_domain="Fer2_3 (E-value: 3.1e-29, bitscore: 91.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00067, bitscore: 10.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVYKIKIRRQESQKSDSYWQEFEFDGSKNSSVANVLKELNSRTPL
                     KDNSGNIVTPISWECSCMVRKCGACAMLINERPRLACSTFLHTLKGSTITLEPLSKFPL
                     VRDLIVDRSILFENLKKLNLWLESEAYMNPWTHEPRYQSARCLMCGCCLEVCPNFSANG
                     TFAGAVAAVNAFRILNEEQESTHLNEISAEYKKKYFEGCGKSLSCHDICPIGLPVEELL
                     VRSNAAAVWGK"
     CDS             6405..6704
                     /locus_tag="ctg178_7"
                     /transl_table=11
                     /translation="MNAMDVALICKALGDANRLEIVQMLSDGEKCGCKLLERFKITQPT
                     LSHHMKILVRCGLVNDRKEGKWHHYSLNCETLMNYKHFIESLTCLGCGDGDCCK"
     CDS             6724..7041
                     /locus_tag="ctg178_8"
                     /transl_table=11
                     /translation="MKKESNSGISFFQRYLTVWVIICMLIGIMLGHFLPGMKEALNYLE
                     YAGISIPLAVLIWIMIYPMMMKVDFKSIKNIGKNPKGLFVTWIVNWLGRFRRAFVQMMK
                     Q"
     CDS             6981..7196
                     /locus_tag="ctg178_9"
                     /transl_table=11
                     /translation="MDCKLAREIPKSFCSDDETIGLVQEIYGTKVNKGICCVFRYNNLP
                     AKNVLPEYVCDYKKRAGLFQRSADLE"
     CDS             7443..9542
                     /locus_tag="ctg178_10"
                     /transl_table=11
                     /translation="MRKKKRKKHTKIITKIVLFSGILIGGGIGIVTIMNRNVPEKRLME
                     YMKYIEKGEYEQMYAMLDQKKSSMNSKEEFIERNSKIYEGIEMSDLSITDITAKRKENG
                     NAAVSYTTNMQTAAGNVEFTNNAVFSHNWTGYHLIWQDQLIFPELSATDKVQVTLEEAK
                     RGNILDRNGRQLAGEGTASSVGIVPGRMENREDTIKKLAEYLGIGADEIEDKLKADWVK
                     ADSFVPVATIPKIQEVDLLTVNPDETVLEEKEKQDTLLKIPGIMLSDVKVRTYYLKEAA
                     SHLVGYVQAVTAEDLQEHKGEGYRTNSVIGKTGLETLYEKELKGTDGCEICIVDANGNK
                     KSVIAYEPKKDGEDIHTTIDGDLQSTLYEQFKEDRGCSVALNPYTGEVLALVSTPSYDN
                     NDFVRGMDNSQWSALNENEDRPLYNRFRQTWCPGSTFKPVIAAIGLKVGAFTANDDFGN
                     EGLAWQKDSSWGDYTVTTLHDYAPVILKNALIYSDNIYFAKAALKIGADQLMQSLNQIG
                     FNQELPFDIKMSESQYSNTDKIETEIQLADSGYGQGQILVNPLHLASIYTAFLNDGNMI
                     KPYLHADGSTSSEIWIKDAFSPQIVLEVMAGLEGVVNNPEGTGYGACREDIRLAGKTGT
                     AELKATKEDTSGTEIGWFTVFTTDRDTENPILLISMVENVKDIGGSGYVVEKDKAILDE
                     YLGNE"
     CDS             9583..10740
                     /locus_tag="ctg178_11"
                     /transl_table=11
                     /translation="MKKIWKIFVGAIFLAVCSGCGIKKEQKKTIEDTKEKIYRECEMLA
                     EGYQSIYENAVKENALYELSTIQKSMDYFGKYGYAVIDSYNQLDMVQSIKVDDFLKKAE
                     KEKNGKTTIFQVIAGDHFIRYDLKTKQRKIDVEVSSFKWKEDTWQETYYHEFRVNSWKY
                     TENGYFFMEEYHPAGYDGPSGYRAFRVAPLNKKCRELNRKYILPFGYTLNKLFTSNWSE
                     KNYDGINFYDVFDRLLSMEEKTDEFKEGKTYEIPKESFEAIFQKYFNISAEILQTGTVF
                     HTETQTYRYRTRGIVYDFAPTPYIPYPEVVSYIENQDGTITLEVNAVWPQKELDQAFCH
                     SVTIRLLDKDRFQYVSNYVSRSEIEVTWYTERLSDEKWEECYGDN"
     CDS             10727..11188
                     /locus_tag="ctg178_12"
                     /transl_table=11
                     /translation="MEIIDMIAKRKLKKMMSVLFISGCFFIGNTKCKGADLEYISQETA
                     NYAVQERGYDLPVDEVVKEEAIEDCKNVMNQMKAIYQKADKGTSSNVVVSETVMEEMQE
                     VLKEKMSLLLHQRRIQIWLIILKWKNFFSGQNRICQEISSYIGLTGMVG"
     CDS             11221..11973
                     /locus_tag="ctg178_13"
                     /transl_table=11
                     /translation="MYLLAVKVVWGMNDNPSIVYVSYTRIEEWKYTEKGWFGYTLCVPK
                     YPEVSEAVDGSSMIRIKPLSDECREVSKRCVYLLGYQGNNLLCSDWDRSDMEGLDYNGL
                     YEYLYRMKYGERYEFSDNSSGIPAEEFENLIMEFLPITAEQIKKWAVFDSEHQTYDWER
                     LGCLNYSPTYFGTSLPEVVEIRDSGEGNNVLVVDAVCDTFICNDAVITSELTVKFNDDK
                     SFKYMGNKILNNGTKEVPKYQYRIKRKN"
     CDS             complement(12001..13797)
                     /locus_tag="ctg178_14"
                     /transl_table=11
                     /translation="MSNWIIHFLISNIFICIFTLVIIGTKKLLKKYLSATTQYHLCFLL
                     FLLLAVPFFPVQIHGSQFFSWLHFFQTDSGLNSGTDTLSELTSNTQNILLNQVNDFSVS
                     ISSQFSGGLNTILFLIWITGVMIMSVLTLHSLNYVRSIKRSALPLQNRQVKTIYYNCLK
                     ELKISHPVSVYSTAFLKSPVLIGIIHPRIYIPIHLISELNPDDMRFMLLHELQHYRHKD
                     TFIGFLMVISNILYWFNPFVWYTLKEILCDREIACDSAVLQMISADEYQAYGTTLINFA
                     EKISSFSSPLAVGMSGNFRQMKRRILNIAVFRKETLYQKMRALIIYLVISAVFIGCTPI
                     LSVDASTQSVYHFSDTDKNISLLDISETFGTYDGSFVLYDNNLDSWKIYDLEEATKRIP
                     PESTYKIYDALLGLESGIITPEHSSMTWNGDAFPFPSWEADQDLNSAMQNSVNWYFQAI
                     DSQLGINRVQGFLNKIEYGNQTTSSNLDLYWSDFSLKISPLEQVTLLKKFNTNEFHLNS
                     QNVFSVKNAIKIASTPNGNFYGKTGTGRVNGQDINGWFIGYVETSDNSYYFATNIQSDS
                     NATGKKAFEITSDILKKLHIWN"
     CDS             complement(13808..14179)
                     /locus_tag="ctg178_15"
                     /transl_table=11
                     /translation="MSLPQISEAEFEVMKIVWKYAPINTNEITEKLTLTTSWSPKTIQT
                     LIKRLVSKKALSYEKQSRVFVYTPLVQEDEYMRQESNSFLKRYYNGNLSSMLASYLEDD
                     KLSSTEIDNLRHLLSKHQK"
     CDS             14301..14714
                     /locus_tag="ctg178_16"
                     /transl_table=11
                     /translation="VKKIEIIERITDANGSISENILTSWEHKNQFIPEIIRFGELKIYL
                     QERIVKKNDSDVHLSKYEYDILLLLAKNPGRIFGKEMVYDLVWNEPYSGDYNVVMRHIC
                     NIREKIEDDPGQPLYIQTVRGVGYRFNGNLGSE"
ORIGIN
        1 tgagcaagaa gcccccactt caaaatctgg gatttaagtg gtgggagcat gtcacttgta
       61 aaatttatgg ggaactaaca tcagcttatt gacataaatt taaaaataag tataataata
      121 gttgattaat tgttcaacta ttattatttg gaggtgaata tatgccaaaa acgtcttata
      181 tttgtaattg cgatgtaatt catgaggata ttgtgaatga tgtgaaatcc aagatgcagc
      241 caaaagatga ttatatccag ttggcttctt tgtttaagct atttggagat ggaactagag
      301 tacaaatctt acacgctcta gaacagagtg agatgtgtgt atgtgatctt gcagtgctac
      361 tgggggtaac aaaatctgca atttcgcatc agttaaaggc attacgcctt gcgaatctgg
      421 taaaattccg taaagaagca cagatagttt actactcgct ggcagatgat catgtgaaag
      481 agattattga caagggattt gaacatcttt ggcagaaata atatttttta acattatagt
      541 tgagtaattg aacaattaaa caaattatga ggagattagc atgaaacgca tatttctatt
      601 aaaagggttg gactgtccaa attgttccgc aaaaattgaa aaagaagtcg gagagttgga
      661 tggagtgcaa tcctcagtgg taaatctgat gaagcagacg cttacaatca atgttactca
      721 gacagccgca gatacgatag ccagtcagat tgaaacgatt gtttatagtc atgagccaga
      781 tgtggaggtt caggaagaaa caattatccc cgttacaaag agttatttgt taaagggctt
      841 ggactgtccg aactgctccg caaaaattga aaaagaagtc ggagaattgg atggagtaca
      901 atcctcagtt gtaaatttga tgaagcagac gctgacaatc aatgttgctc cagttgccgc
      961 aaatacaata gccagtcaga ttgaaacgat tgtccacagc catgagccag atgtagaagt
     1021 ttccgaaatt gcacaggaat actatatacc tgcaaaaaaa caggatacca atacatccta
     1081 taacaatgag gacaagaagt tgacgattcg tttagcgatt ggcgcagcaa tctatggtat
     1141 tggtatggca ttgacagttt ttgcgaaagt gccactgcct gtcgagttag tttttctcat
     1201 tgtctcctat attattcttg gcggggatgt tgtatggcaa gctgtgagga atatttcaaa
     1261 gggacgtgtg tttgatgaac atttcctgat gagcgtttct acgattggtg cttttgtcat
     1321 tggtgaatat ccggaagcag ttgctgttat gctgttctat caagttggtg aatttttcca
     1381 gtcattggct gttgagcgtt ccagaaaatc tatatcagat ttaatggata tacgtccgga
     1441 ttgtgctaca gtcagaagga acggagaatt gattaccata tctcctgaaa gtgttgccat
     1501 tggtgagatt attattgtaa agcctggtga aaaaatccca ttagacggtg tggtattgga
     1561 tggagattct atgctggata cgagggcttt aactggagaa tcggttccga gaagcgttca
     1621 taaaggagac gaagcacttt ccggttgtat gaatcagacg ggtgttttaa cgattaagac
     1681 aacgaaagca tttggtgaat ctactgcttc aaagattatt gatcttgtgg agaatgcgtc
     1741 cagtagaaaa gcaccaacag aaaatttcat tactacattt gcacgttatt acactcctgt
     1801 tgttgtaatc ttagcagcta ttctggcaat tctgccaccg atccttcttg gtggaggttg
     1861 gacagagtgg attcgcagag gatttgtttt ccttgtggta tcttgcccat gtgcattggt
     1921 catttcaatc ccgctgactt tcttcggagg tattggtgcg gcatctaaac gaggtgttct
     1981 tgtaaaagga agtaattatt tagaggcgct taataatgtc agcattattg tgttcgataa
     2041 aactggaaca cttacaaagg gtgttttcaa tgtgactgat attctgcctg caaatggatt
     2101 ttcaaaagaa caggttctgg agtatgcggt ccaggcagag agcttttcta accatcctat
     2161 tgcaaaatcc attctctctg cttatggaaa agaaattgac caatcagtta tctctgatta
     2221 caaggaaatt tccggatatg gaatcagtgc catggcagga aagaagaaag tttatgccgg
     2281 caatacgaaa cttatggatt cagagcatgt ggagtacaca gcctgtgaaa aagttggtac
     2341 aaaggtttat gtagcagtag atggtcaata tgccggatgc attttgataa cagatgaagt
     2401 aaagccggac agcaaaaaag caatttctga tttgaaacat atcggtgtgg aaaaaacagt
     2461 catgcttact ggtgatgatg aaaaaatcgg aaaggctgtt gcggaagaat tgcagttgga
     2521 tgaatattat gcacaactgt ttcctgatca aaaagtggaa aaggttgagc ttttagacag
     2581 taaaaagaga cagggaagca aattagcttt tgttggtgat ggtatcaatg acgctcctgt
     2641 ccttgctcgt gcggatgttg gtattgcaat gggtggtctt ggttcagatg cggccattga
     2701 agctgcggat gtggttctga tgacagatga accatctaag ctggtggatg cgattgatgt
     2761 ggcaaaagcg acaaagcaaa ttgtcatgca gaatatagtg attgcccttg gaattaagag
     2821 tgtgttcctg attcttggcg ctcttggtat tgcgggaatg tgggaagctg tatttggtga
     2881 tgtaggcgtt accataattg ctgttttgaa cgcaatgaga attttgaaaa aataggaaat
     2941 gaggtgggaa tgtgaaacga aaactgattc tgttagttgt tacgattgtt tttcttgtag
     3001 gttttggtgt catattacat tcaccgcctt ctatgattga tgcagtcaca ggagcaacac
     3061 cgaagtcaaa aaaggcggct caagcctccg cacagttgga aggctcttat gttctcggta
     3121 ttaatatgat gtcagatggt ctcgacaacg agaacacccg gaataaatta aaagaattgg
     3181 cactggacga ttcggaaaca aatgaaacag atctcatgaa aacggacatt agttttcggt
     3241 tatatgtatc tgagacggat tatccgcttg ccagttatgc taagaaactc tgtgacaggt
     3301 tgaaacaggc cggttttttc gtagatctga aagagtacag taacacaatg atgctatcaa
     3361 gagtggtaag tggaaagtat gatgtattcc tggcatcgga tgattttatt gacgttacaa
     3421 cgttatcaca gatggactat atgatcatgg acagcgaaga aatgaggtga gcgggaattt
     3481 atgagaaaat ggaatacgat tttgtctgtt ttaatgcttc tcatttttat gattcatgga
     3541 atcatgggaa gctttatgct gaacggagtt ggaagtagtg cagggaaact tcttgcatgg
     3601 attggtgttg gtattcttgt tgtgcatacg gtgattggtg tcatcctgac agttcagagt
     3661 ttacagacag cgaagcaatc cggaaaaatg tatctgaaac agaacgccat attctgggcg
     3721 agacgagcca gtgggctggc aatactgatc ctgctgttct tccatattgg cttgtttgga
     3781 aaggtgcaga atgggacata tattttgttc ccttttacaa cggtaaagat ggtaactcag
     3841 cttttgttcg tggcggcaat ctttgttcat atttttatca atatccgccc attgctcgta
     3901 tcgctgggaa tcatcagtta taaagaacga aggggtgata tttatttgat tctttcggtg
     3961 ctccttctgt ttatagcggg cgcagttatt ttctattata ttgggtggca atatctatga
     4021 gtaagacaat tattattata ggtgctggac tggcaggact ttcagcggct ttgcaggcag
     4081 cggaaaatgg atgcaatgta aaactggttt cctcccttcc gtcagagcgg gcacagtctg
     4141 ttatggcgga gggcggtatc aacgcagctt tgaatacaaa agatgaaaac gacagtcccg
     4201 aagaacattt tacagataca ataaaggcag catgtggtct ggcagatcca aatgcagttt
     4261 ggggaatgac acaggcagca ccggagctgg tgcactggct gctaaaactt ggagttaaat
     4321 ttaacatgag tggctatgat gatgtggatc tgcgaaattt tggcgggcag aaaaagaaac
     4381 ggactgcttt tgcacagagc gataccggga agcagatcat gacagctatg atagacgctg
     4441 ttcgcaggaa agaagcattt ggtatggtag aacggttcag ccatcattct ttcctaacac
     4501 ttcgtctgtg tggcaatatt tgttgtggct gcgtaatcag ggatgaatac agtcaggaga
     4561 ctgtggaatt accgggggat gcggttattg ttgccaccgg tggtatgcac ggattgtttg
     4621 gaaatacaac gggttcgctg agcaatacag gagaagtcac cgcagaattg ttccggcttg
     4681 gtgttcctct ggcaaatggc gagatgatcc agtatcatcc gacaactgtg aaatgtggtg
     4741 gaaaacgcat gctcatcagc gaggcggcca gaggggaagg tggcaggttg tttgccatga
     4801 aagatggaaa acaatggtat ttcatggagg aaaaataccc ggagcttgga aatctgatgc
     4861 cacgagatat taccgccaga gagatatgga aggtcagcca tgaatcagag gtatttcttg
     4921 acatgacgga aatatcggag gagattattt caaataagct atctggtctg gcagacgatt
     4981 gtatgaccta tctgcataaa gatatacgaa aggaaccggt gtctgtttta ccgggaattc
     5041 actattttat gggaggtatt ctggtggatg agcagcacag aacgccgatt cagaatcttt
     5101 acgctgccgg agaatgctgt gcccaatatc atggtgccaa ccgtcttggt ggaaattctc
     5161 tgttaggagc gttatacgga ggacgtgttg cggcaaaatc agcatgtgaa caggcagatg
     5221 tagtagatct atcttgtgcg acacagatag attttccacc agcgtctcaa atttcagaaa
     5281 taaagcaatt aaacaaagtg atgcaggaga ctatgggcgt tgtcagaaat gagaatacgt
     5341 tgttaaatgg gattcaaacg gtacaagcgc tgacaggaaa tcttccattg cttggcatgg
     5401 cagttctaaa gagtgctctt gcaagaaaag aaagccgtgg tgcacactgg cgggaggatt
     5461 atccgaagag caatgacaat gattacctta aaacaacggt agccagattt gatggaaagc
     5521 agatacagat ttcctttgta cctgttccag aaaggcggtg attcacttgg tatataaaat
     5581 aaaaatcagg cggcaggaga gtcagaaatc agatagttat tggcaggaat ttgagtttga
     5641 cggaagcaaa aacagctctg ttgccaatgt tctaaaggaa ttgaacagta gaaccccttt
     5701 gaaagataat tcagggaata tagttactcc catcagctgg gaatgtagct gcatggtgcg
     5761 aaaatgtggg gcttgcgcca tgctgattaa cgaacgtccg aggctggcat gctctacatt
     5821 tctacatacg ttaaaaggtt ctacaatcac cttggaacct ttaagcaaat ttccgcttgt
     5881 aagagatttg atcgttgacc ggtcaattct gtttgaaaat ttgaaaaaac tgaacctttg
     5941 gcttgaaagt gaagcttata tgaatccgtg gacacatgaa ccgagatacc agtcggcacg
     6001 ctgtctgatg tgtggctgct gccttgaagt gtgtcctaac ttctctgcaa atgggacttt
     6061 cgcaggtgct gttgctgcag tcaacgcatt tcggattctg aatgaagaac aggaaagcac
     6121 tcatttgaat gagatttctg ctgaatataa gaagaaatat tttgagggat gcgggaagtc
     6181 gttatcttgt catgatattt gtccgattgg tctgcctgtg gaagaactgc ttgtaaggtc
     6241 gaatgcagcg gctgtttggg gcaaataaaa tggatgataa aagctataat gaatgtatga
     6301 agagaatcaa aaacttgatt ctcttttttt aaaatacata cattgacaaa tatctatgta
     6361 tatattatat tgaacataga caatgatcaa tgtgaggtgt caatatgaat gcaatggatg
     6421 tggctttgat atgcaaggct ttgggcgatg cgaaccggct ggaaattgta cagatgctgt
     6481 cggatggaga aaagtgcggg tgtaaacttt tggaaagatt taaaattacc cagccaactt
     6541 tatcccatca tatgaagata ctggtaagat gcggccttgt gaatgatcgt aaggaaggaa
     6601 aatggcatca ctattctttg aattgtgaga cattgatgaa ttacaaacac tttatagaat
     6661 cccttacttg ccttggatgc ggtgacgggg attgttgtaa ataatttaag gagagcagat
     6721 atcatgaaaa aagaatcaaa ttcaggaatt agttttttcc agcgttacct gactgtatgg
     6781 gtaattatct gtatgcttat aggaattatg ttgggacatt ttcttccggg aatgaaagag
     6841 gcactgaact atctggaata tgcaggaatt tctattccgc tggcagttct tatatggatt
     6901 atgatctatc caatgatgat gaaggttgac ttcaagagta ttaaaaatat cgggaaaaac
     6961 ccgaaaggtt tatttgttac atggattgta aactggctag ggagattccg aagagctttt
     7021 gttcagatga tgaaacaata ggattggtac aggaaatata tggaacaaaa gttaataaag
     7081 ggatttgttg cgttttccgc tataataatc tgccagcaaa gaatgtgttg cctgaatatg
     7141 tttgtgatta taagaaacga gcagggttat ttcaaagatc agcagattta gagtagttct
     7201 ttttttctga gagaaaatta aaaatcgttt ttggttcttc tggagagtga ttatagcgtt
     7261 tgggaaacat ccggagaaac cattacctca gggtgtcgtg aagttcttta tcaaagaagg
     7321 ctttgagatg ccctttcttt tttatccaaa tcttacatat ataaacctaa gaaaaagctt
     7381 gacgtttaaa tattacaagt gtaatattta agaaaatatg aaaaaaggag aaataaaact
     7441 atatgagaaa aaagaaaaga aaaaaacaca cgaagattat cacaaaaata gttttattta
     7501 gcggtatatt gattggtggt ggaatcggta ttgtaacaat aatgaatcgt aatgttcctg
     7561 aaaaaagact aatggaatat atgaaatata ttgaaaaagg ggaatatgag caaatgtatg
     7621 ccatgctgga tcagaaaaaa agcagcatga acagtaagga agaatttata gaacgaaatt
     7681 ctaaaatata tgaaggcatt gagatgtctg atctgtccat aaccgatatt acagcaaaaa
     7741 gaaaagaaaa cggaaatgcg gcagtttcct atacaacaaa tatgcagact gctgcaggaa
     7801 atgtagaatt taccaacaat gcggtatttt cacataactg gacaggatat catttaatct
     7861 ggcaggatca gttgattttt ccagagttat ctgcaacgga taaagttcag gtaacgttag
     7921 aagaggcaaa aagaggaaat attttagaca gaaatggtcg ccagctggct ggagagggaa
     7981 ctgcatcttc ggtaggaatt gttccgggca gaatggagaa cagggaagat acaataaaaa
     8041 aactggcaga gtatcttgga attggagcag acgaaattga ggataagtta aaagccgatt
     8101 gggtaaaagc agattctttt gtaccagtag caacaattcc taaaatacaa gaggtcgatc
     8161 ttctgacagt gaatccggat gaaactgttc tggaagaaaa agaaaagcag gacacattat
     8221 tgaagattcc aggtattatg ttatctgatg taaaagtacg aacttattat ctaaaagaag
     8281 ctgcctctca tctggtaggg tatgtacagg cggttacagc cgaggatttg caggaacata
     8341 aaggggaagg gtatcgtaca aacagtgtga ttggaaagac gggactggaa acgctttatg
     8401 aaaaagaact aaaagggaca gatgggtgtg agatctgtat tgtagatgca aatggaaata
     8461 aaaaaagtgt cattgcatat gagcctaaaa aagatggaga agatatccat actacgattg
     8521 atggcgatct tcaaagtact ctttatgaac aatttaaaga agacagagga tgttctgtag
     8581 ccttgaatcc ttatacaggg gaagtactgg cgttggtaag tacgccatct tatgataata
     8641 atgattttgt acgtggaatg gacaatagcc agtggagtgc attaaatgaa aatgaagaca
     8701 ggcctttata caaccgcttt cgccagacat ggtgtccagg ctcaactttt aaacctgtaa
     8761 ttgctgcaat tggattaaaa gtgggggcat ttactgcaaa tgacgatttt ggaaatgagg
     8821 gtctggcatg gcagaaagat tcctcgtggg gagattatac agtgactaca cttcatgatt
     8881 atgcacctgt gatcttgaaa aatgcgctta tttattcaga taatatttat tttgcaaaag
     8941 cagcattaaa aatcggtgcg gatcaactga tgcaatctct aaatcaaata ggatttaatc
     9001 aggaacttcc atttgatatt aaaatgtcag agtctcagta ttctaatacg gacaagatag
     9061 aaacagaaat ccagcttgct gacagtgggt atggacaggg acagattctg gtaaatcctt
     9121 tgcatcttgc aagcatttat acggcttttc taaatgatgg aaatatgata aagccatatc
     9181 ttcacgcgga tggaagcact tccagtgaaa tctggataaa agatgctttt tcaccacaga
     9241 ttgttttgga ggttatggcg gggctagagg gtgtagtgaa taacccggaa ggaactggtt
     9301 atggagcatg ccgggaagac attagattag caggaaaaac cggaacagcg gaactgaaag
     9361 ctacaaaaga agatacatct ggaacagaaa ttggctggtt tacagttttt actacagata
     9421 gagatacaga gaatcctatt ttgctcatca gtatggtaga gaatgtgaaa gatattggag
     9481 gaagcggtta tgtggtggaa aaggataagg cgatactgga tgaatatctc ggtaatgaat
     9541 aatttttacc tttaaatatt acaaatgtaa gaggaaaatg atatgaaaaa aatttggaaa
     9601 atatttgtgg gagctatttt tcttgctgtc tgtagtggat gtggcataaa gaaagagcag
     9661 aaaaagacaa ttgaagatac gaaagaaaaa atttacagag agtgtgaaat gctggcagaa
     9721 ggctatcaga gcatatatga gaatgctgtg aaagaaaatg cactatatga gctgagtaca
     9781 atacaaaaaa gtatggatta ttttggaaaa tatggatatg cagtaattga ttcctacaat
     9841 cagctggata tggttcaaag tattaaagta gatgattttt tgaaaaaagc agaaaaagag
     9901 aagaatggaa aaactactat atttcaagtt atagcagggg atcattttat ccggtatgat
     9961 ctgaaaacca aacagaggaa aatagacgtt gaagtaagct cttttaaatg gaaagaggac
    10021 acttggcagg aaacatatta tcatgagttt agagttaatt catggaaata tacagaaaac
    10081 gggtatttct ttatggaaga atatcatccg gctggatatg atggaccgtc tggatatcgg
    10141 gcctttcggg tagcaccgtt aaataaaaaa tgtcgggagt tgaatcgaaa atatatactt
    10201 ccttttggat atacacttaa taaattgttt acttctaatt ggagtgaaaa aaattatgat
    10261 ggaataaatt tttatgatgt ttttgaccgt ttactttcaa tggaagaaaa aactgatgaa
    10321 tttaaggaag gaaagactta tgaaatccca aaagaatcat ttgaagcgat atttcaaaaa
    10381 tattttaata taagcgcaga gatactgcag acaggaacgg tatttcacac ggaaacacag
    10441 acatatcggt atcgaaccag aggaatcgta tatgattttg ctcccacacc atatattcca
    10501 tatccggaag ttgtttccta catagaaaat caagatggaa caataacact ggaagtaaat
    10561 gcggtatggc cacaaaaaga attagatcag gcgttttgtc atagcgtaac cattcggctg
    10621 ttagataaag atagatttca atatgtatcc aattatgtat caaggtcaga aatagaggtt
    10681 acctggtata cagaaagatt atcagacgaa aagtgggagg aatgttatgg agataattga
    10741 tatgattgca aaaagaaaac tgaaaaagat gatgagcgtt ttatttattt cgggatgctt
    10801 tttcatagga aatacaaaat gtaaaggggc tgatttagaa tatatttcac aggaaactgc
    10861 gaattatgct gtacaagaaa gaggatatga tttgccagta gatgaagtcg tgaaagaaga
    10921 agctattgaa gattgtaaga atgttatgaa tcagatgaaa gccatttatc aaaaggcgga
    10981 taaaggaact tcatcgaatg tagtagtttc tgagacagta atggaagaaa tgcaggaagt
    11041 attaaaggaa aaaatgtccc tgttattaca tcagcgccgt attcaaatat ggctaattat
    11101 tctaaaatgg aagaatttct tttcagggca gaacaggatc tgccaggaga tatcgtctta
    11161 tataggatta acagggatgg tgggatagaa agactcaaat tcaattatga tgggacagat
    11221 atgtatttgt tggctgtgaa agttgtttgg ggtatgaacg acaatccatc tattgtatat
    11281 gtttcgtata caaggataga agaatggaaa tatacagaaa aaggctggtt tggttatacg
    11341 ctatgtgttc caaaatatcc ggaagtatca gaagcggttg atggcagttc tatgataaga
    11401 attaaacctt taagtgatga atgcagggaa gtttcaaaga ggtgtgtgta tttgcttgga
    11461 tatcagggga ataatctttt atgttctgat tgggatagat ctgatatgga agggttagat
    11521 tataatggtt tatatgaata tttatatcga atgaaatacg gggagagata tgagttttca
    11581 gataactcaa gtggaattcc ggcagaagag tttgaaaatc tgataatgga gtttttgccg
    11641 ataacagcgg agcaaattaa aaaatgggca gtatttgatt cggaacatca aacttatgac
    11701 tgggaacgat taggttgttt aaattatagc cctacttatt ttggaacatc tttaccggag
    11761 gtcgttgaaa taagagatag cggagaggga aacaatgtgc tggttgttga tgctgtatgt
    11821 gatacattta tatgtaatga tgccgttatt acaagtgagc tgactgttaa gttcaacgat
    11881 gataagagtt ttaaatatat ggggaataaa attctgaata atggtacgaa agaagttccc
    11941 aaatatcaat atagaataaa aagaaagaac tgataacaac tatcagccct ttcatatttg
    12001 ttaattccat atatgtaatt tttttaagat atcagaagtg atttcaaatg cctttttgcc
    12061 agttgcatta gaatcacttt ggatattggt tgcaaaataa tagctgttat cggaagtttc
    12121 tacatatccg ataaaccagc cgttgatatc ctgtccgttg acacgaccgg ttccagtttt
    12181 tccgtagaaa ttaccattag gtgtactggc aatttttata gcatttttaa cagaaaatac
    12241 attttgggaa tttagatgga attcatttgt gttaaatttt ttcaataatg ttacttgctc
    12301 taaaggcgag atttttaatg aaaaatcgga ccagtataaa tccagatttg aactggttgt
    12361 ctggtttcca tattctattt tattcaaaaa tccctggact ctgttaattc cgagctgcga
    12421 atcaattgcc tggaaatacc agttaacgga attttgcata gcagagttta aatcctgatc
    12481 agcttcccag gatggaaaag gaaaggcatc accattccat gtcatggaag agtgttctgg
    12541 tgtgatgatt ccggattcca accctaataa tgcatcgtat attttgtagg tagactctgg
    12601 cggaatacgt ttggtggctt cttcaagatc gtatattttc caggaatcca aattattgtc
    12661 atacaaaaca aatgatccat catatgttcc aaatgtttcg gatatatcta acagggagat
    12721 atttttgtct gtatcactaa aatgatatac gctttgagta gaggcatcaa cggataaaat
    12781 gggtgtacat ccaataaaaa cagcactaat gaccagataa attatcaatg ctctcatttt
    12841 ttgataaaga gtttctttcc taaaaacggc gatgttgaga atacgtcgtt tcatctgcct
    12901 gaaatttccg gacattccaa ctgccagtgg agaggaaaaa gaggatattt tttctgcaaa
    12961 attaatcagt gtagttccat aagcttggta ttcatcagca gaaatcatct gcaatacagc
    13021 agaatcacag gctatttcac ggtcacagag aatttctttt aaagtgtacc aaacaaaagg
    13081 gttaaaccag tagagtatat tacttatgac catgaggaag ccaataaatg tatctttgtg
    13141 acggtaatgc tgtaattcgt gtagcagcat aaaacgcata tcatcaggat tcagttcgga
    13201 aattaaatgg atgggaatgt aaattctggg atgtattatt ccgattaaaa ctggtgattt
    13261 taaaaatgca gtactgtaga ctgatactgg gtgagagatt ttaagttcct ttaaacaatt
    13321 gtaataaata gtttttacct gccgattttg aagcgggaga gcagatcttt ttatggaacg
    13381 tacatagttt aatgaatgaa gggtgaggac tgacataatc ataacacccg ttatccatat
    13441 tagaaagagt atggtattca agcctccaga aaattgacta ctgatggaaa ctgaaaaatc
    13501 attcacctgg tttaacaaaa tattttgtgt attactggta agttcggata gcgtgtcggt
    13561 accagagtta agtcctgagt cagtttgaaa aaaatgtaac catgaaaaaa attgtgagcc
    13621 atgaatctgt acaggaaaaa atggcacggc aagtaataaa aataaaagaa aacagagatg
    13681 gtactgtgta gtcgcagata aatatttttt cagaagtttt tttgttccga ttattacaag
    13741 tgtaaaaata catatgaaga tattactgat taaaaagtgg atgatccagt tgctcattca
    13801 aaacctccta tttctgatgt tttgataata aatggcgtaa gttatcaatt tctgttgaag
    13861 agagtttatc gtcttcaagg taagaagcca gcatagaaga aagatttcca ttataatatc
    13921 gctttaaaaa agaattgctt tcctggcgca tatattcatc ttcttggact aatggagtat
    13981 agacaaatac ccggctttgt ttttcgtagg aaagagcttt tttggaaaca agtctcttga
    14041 taagagtttg aattgttttt ggactccagc tggtagttag agtaagtttt tctgtaattt
    14101 catttgtatt gatgggagca tatttccata caattttcat aacttcaaat tcggcttctg
    14161 aaatttgggg tagtgacata ataaaatcct cctgctaaat cctacatatg taataaatat
    14221 attatattac ttgtagaaga aaaaagtcaa atggcagatg atatatagaa tataaaatta
    14281 ataatgtaga ggcaataaag gtgaaaaaga tagaaattat tgagagaatc acagatgcta
    14341 atggaagcat aagtgaaaac atattgacta gctgggaaca taaaaaccaa ttcataccgg
    14401 aaattataag gtttggagaa ttaaaaatat atctacagga acgaattgtt aaaaagaatg
    14461 atagtgatgt tcatctttca aaatatgaat atgatatttt acttctttta gcgaaaaatc
    14521 caggtagaat atttggaaaa gaaatggttt atgatctggt atggaatgaa ccttattccg
    14581 gtgattataa tgtggttatg cgacatatct gcaatatcag agaaaaaata gaagatgatc
    14641 ctggacaacc attatatata caaacagtac gaggtgtagg atatcggttt aacgggaatt
    14701 taggcagcga gtgaaatcgc tgcctattat tatggtttta caaagaag
//
