LOCUS       gnlProkkaILBCOGMJ_64   12942 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ILBCOGMJ_64.
ACCESSION   gnlProkkaILBCOGMJ_64
VERSION     gnlProkkaILBCOGMJ_64
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:30:25
            Original ID  :: gnl|Prokka|ILBCOGMJ_64
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12942
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12942
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[311:2942]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      312..2942
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..12942
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12942
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             176..319
                     /locus_tag="ctg46_1"
                     /transl_table=11
                     /translation="MDENIKYELAEAEKLEVIDNAGVAENEKKSIVTVLLSLSCCGHIM
                     NA"
     CDS             312..2942
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     839.8; E-value: 5.1e-254)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_2"
                     /sec_met_domain="DUF4135 (E-value: 5.7e-95, bitscore:
                     311.0, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.3e-58, bitscore:
                     189.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLENICIRILILDISEKKSNHELYGFTVHEEYNFYIKHFWKNESY
                     KCDLAIRYAEGSRLQKLKEKYFVILQNEINEKINIDKDMISKKFHENMNEFQMLNKDQG
                     DIHKNGRSVSKIEFDNGSILYYKPHSLDKDIKYQQLYKYLCEKAGISCREVRCLSRQTY
                     GWEENIENKSCNTKEEIERYYFRLGIHLFLGYALGATDLHGENIVAYGEHPVIIDMETY
                     PGYITKNSGSSTEEKAEIKIREKIMTSVLNTGILPVLTWGTGNNRVLMSAVNMHGKIRT
                     PFKMPVVKDDKTSNIHIEYEQVEFEIKECIVRLNGEVVNSEEYTGEIIRGFRMAYTEIL
                     QNQKLRNMLKTFFQGKSRVILRHTQQYYMYLFASFHPDYMKDRKQREELLQVLHKKGET
                     QLQKELRDYEIQSLLELDIPYFEIDGNSRSIFDGNGKEYQGYLPCTPYESWIEHMKQLS
                     CQDMEQQCDYIRLSMGLLNHGYIGEKNPRWADENTCIHQIAEWICRTAVIDGADIGWAG
                     LHFWDNGYWSLKPCGMYLYDGIAGIVLFLAKYLDRYQDSSCRQDVEKIYKLAIEKLEKY
                     TDLRCEQNEVPEPLATGLYDGESSIVYVYLILYEITGQEKWIKNAQKHFEIVAKLLPKD
                     ENMDYLSGNAGAIVAAMKLYQLTGEIEYCTAAVETEKDLWKKGQRMEVGYGWKLKNLKY
                     PLSGLSHGNSGFLMAYVELYKMTYDQEYLKKIKLLLSYEDILYSEDLKNWIDLRDPDGR
                     KTMRGWCHGAPGILLSRMSIMDILPDDKQIKKDILRAVSTLFHNEREKKICLCHGMTGN
                     LLIMKKYLEKNPDDDLRQKYERQFSNLKEQLQDMRSLMVTETLNPAFMNGITGVGMAMM
                     LLNMD"
     CDS             complement(2963..3493)
                     /locus_tag="ctg46_3"
                     /transl_table=11
                     /translation="MKSLLQLIHDYHSGVKNAGEEILKRMEPLIKSYASRIHCMERDDA
                     TQELYLTLLNTLPYLNGKNFSEGECVRYMQTAIENRYRALCRYHLSEPEREDFDTCSLT
                     LQADNPFDETLYDITTYIESFPVQSMEYKILSLFFYQYKTDSEIASILHVSRQYINRQK
                     KKLLKTYFFRHPD"
     CDS             3712..3942
                     /locus_tag="ctg46_4"
                     /transl_table=11
                     /translation="MESTVMETAISQGIWAVLAVFLLIYIVKSNEQRDAKQEEREKNYQ
                     TVIENLTEKFQILNQVQNDLKEIKDNLLNKN"
     CDS             4148..6262
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="MKEYKVITALFLSAVMLGTAPLTVWGAESFSTGESFSDGTENIPD
                     IVTDSALSGESSERDYELSIETGTDVELTESDFYDPEFRVEKYVKVRNSGKKETRVRVD
                     ASGLKNFEVDDQMAKWSEDYEEQDSKRLLKPGETLDFFVLPKQEYGTYDETFDFLADDG
                     SRYPVHITMNREKNPTEKKSLEITEKSSESFPIMHWGYKTLPEARIYVLKNFTDMDMEL
                     SFDYSKDCSVSLCGNTSLAPGESTELSLCPQMGLPVGEHDLGVTVTAKTATGETITKKI
                     WDSFRVDSRTFQGLVDTIEPVTGITNGVEKTADALHLPSVLKVYGAEVDGEKTTFSADV
                     KWDVENCAYNPKNTASQSFTVNGQLELREGENNEELDTSVKIKVQVDAYKGLNRPVIDS
                     TWTRVITNYAELSLRDTSNEADGYFFVAAESQKELEKENYIAQVKVAKSELNHYPKLKY
                     IPEGTHYLYCRAYKEESGHTEKYGEWSEGFLLKVNIKTPNAPVVQKLQVKKNDVKIILG
                     SNTEELDGYDVVAARSKDGDEPSDYIKVQCKYSGNSKELILKGVPKGNWYIGVHGYKYL
                     DGSNKKVLSKWAEVQKVTVKTSLVTGKPAVKSAKVSRQGTKRKVTVKFTVPKACDGTDW
                     VLAKKVSQSEDGSYTYVSGYAYTKKNQTKTTVIFKNVKPGVYYLTGRAYVKGYAKNYTK
                     WSEVKKVVVK"
     CDS             complement(6272..6475)
                     /locus_tag="ctg46_6"
                     /transl_table=11
                     /translation="MPETLTFSVVNWKESDAECTFTVVNSGFGYTTQLQNKYYHTSFGL
                     FILTNNTFFFDIYMQKKNKFLV"
     CDS             7001..7717
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 213.6; E-value:
                     5.3e-65)"
                     /gene_kind="transport"
                     /locus_tag="ctg46_7"
                     /transl_table=11
                     /translation="MSEMTDAYVKLDKVSKIYGTKEVKIVAVDEISFEIAKGEFVVIVG
                     PSGAGKTTVLNILGGMDQATSGEVLVDGRNIARYNSRQLTGYRRNDIGFVFQFYNLVPN
                     LTALENVELALQICKNPLDAREVLEEVGLKDRLTNFPAQLSGGEQQRVSIARALAKNPK
                     LLLCDEPTGALDYQTGKAILKLLQDMCRERGMTVIVITHNSALTPMADRVIKIKNGKVS
                     RMTMNDHPTPIEEIEW"
     CDS             7718..11503
                     /locus_tag="ctg46_8"
                     /transl_table=11
                     /translation="MMNMKAMHKDFWMEIHKSKARFISIFMIVALGVAFFSGIQASSPD
                     MRFSGDAYYDETNLMDIKVVGTLGLTEDDVAAIRKVDGVENAEGAYGTDVMCGEGEKQK
                     VLHVEAVDQTMNRISVTEGKAPEKSGEIFLDCIFAESNGYEVGDQITLKEGGDSELLKK
                     TDYTVVGLGESPLYISYNRGNSTLGSGEVNGFAYVFPEDFDQEVYTQIYVQAHGAQDLI
                     SYTDAYDSLIERVQERVEGIEAERCQVRYDEIVEEANDKLADARQELEDGKKEADEKLA
                     DARQELEDGKKKLKDGKKEYKDGKKKLADAKKELEDGKARLADAKKELEDGRSQLASAK
                     EQLASGREQIASAKEQLNAGWAEVSENQAKLDDGKAQLEDGKNQLSAGEKQVADAKTQL
                     TQSQQELDNGKAQIQSGREQIAATRQDLNAKKESCNQGLAQIEQQEAELAEGEAQLEGA
                     RSQLAALQAQYEQAQASGTYSEEDLAALAAQISAYQEQVDSQAAQLEASRNQIAAARSE
                     LESGLSQVESGLAQLDAKEAELNQQEAAFPDAQAKIDAGWKEVKAQEKKLEPARKEIQE
                     KEAQLESAQEQIDAAKAKLNSGQAQLEEKGAELASGEAQIRENEGKLASGEKEIADNEQ
                     KLRDGEKEISENEQKLKDSRKDIKKAEKDLEEGKKEYEDGKRDAEKEIADGEKKIQDAQ
                     DEIDDISMPEWMVTDRNDLPEYSDYGDNADRMRSIGQVFPVIFFLVAALVSLTTMTRMV
                     EEQRTQIGTMKALGYGKYAIASKYLLYAFLATVGGSILGILIGEKILPLVIINGYGIMY
                     KGMMNNIQIRYEFKFAMIAAGAATVCTVGSTIFSCYRALAETPASLMRPPAPKEGKRIL
                     LERIPLFWKHLNFTWKSTLRNLFRYKKRFFMTIFGISGSMALMLVGFGLRDSIMDIARR
                     QYQELQHYTGTIIDDEEATDKERQELDEFLENNSQIERYTHVQFTKMSVPRNKSNISVY
                     VYVPENLGTFNKDVTLQDRKTKEKYKLTDAGTVISEKTASLTGLKVGDTMTITKDGKNY
                     ETKIAAVTENYMGHYIYMTGNVYEQTFGEKPNYSATVFTVKEEYKESESEVGNEILKHP
                     AALSISYTSSLEAQLHRMLGALDTVIIVLIISAGMLAFVVLYNLNNVNITERQRELATL
                     KVLGFYDTEVSAYVYRENVILTFIGVLAGAVFGIILHRYIIRTVEVDAVMFGRNINPVS
                     FLYCGLLTIGFSMIVNLFMHQKLKKIDMVESLKSVE"
     CDS             11610..12815
                     /locus_tag="ctg46_9"
                     /transl_table=11
                     /translation="MGTANQIEQELMNYISDHKIRNTHSHHLPEQAMVDFDLDKLINNT
                     YLQWQQVTPGTTAESRNAYLEKTRYKSYFVWLQKAIGELYGISEPITAQNWDQISDRIR
                     KAHQNPDFYMDVLKNKCKYQKVIVDTYWNPGSDNGRPELFTPAFRLDLFFLGYKKGLRN
                     HDGVSLEENFGELPDNLQDYVEWVRKWIIQKKSEGCVALKIAMAYERSLHFEKVTREQA
                     ERVFRLKESDITQEDIRCFQDYLFWKICEIAAEVSLPLQCHTGMGQVIDTNILQLNNVI
                     KNNPETKFVLLHCGFPWVDDLFSIVDGYPNLYPDLTWLPILSYTASKRVMHQLIEMSQI
                     DKICWGCDTWTVEESYGSLLAFRFSLCSVLREKIEDGYLSVNNAKDIIDKILFDNAGKI
                     YV"
ORIGIN
        1 tataagccca gaaatattga aatatcaatg ttctgggctt aagttgacca cattgaggtc
       61 atgggtgggg attggaaagt gtaaagtata tagtaaaaaa gtatgatgga attattgagt
      121 ttgaatatac agaaatgttt tttcaaacgg ttattatgat tgaaggagaa taaaaatgga
      181 cgaaaatata aagtatgaat tagcagaagc agagaaatta gaagtaatag ataatgcagg
      241 ggttgctgaa aatgaaaaaa aatcaattgt aacggtattg cttagtctgt catgttgtgg
      301 acatataatg aatgcttgaa aatatttgta ttagaatatt gattttggat atttctgaaa
      361 agaaaagcaa ccatgagttg tatggcttta cagtgcacga agaatataac ttttatataa
      421 aacatttctg gaaaaatgag tcttataaat gtgatttggc aatacgctat gcggaaggaa
      481 gtcgacttca gaaattaaag gaaaaatatt ttgtaatatt acaaaatgag ataaatgaaa
      541 aaatcaatat agataaggat atgataagta aaaaatttca tgaaaatatg aatgaatttc
      601 agatgttgaa taaggatcaa ggagatatac acaaaaatgg tcgcagtgta tcaaagattg
      661 agtttgataa tggcagtata ttgtattaca aacctcacag ccttgacaaa gacataaaat
      721 atcaacaact atacaaatat ttatgcgaaa aagcaggaat atcctgtcgg gaggtgaggt
      781 gcttatccag acagacatat ggatgggaag aaaatataga gaataaatca tgtaacacaa
      841 aagaagaaat agagcgttat tatttcaggc tgggcatcca tctgtttctc gggtatgcat
      901 tgggagcaac agatcttcat ggagaaaata ttgttgcgta tggagaacat ccggtgatta
      961 tagatatgga aacatatccc ggctatatta caaagaatag tggaagtagt acagaagaaa
     1021 aagcagaaat caaaataaga gaaaaaatta tgacatccgt gttaaacacg ggtatccttc
     1081 ctgttctcac atggggaact ggaaacaata gagttcttat gagtgctgta aatatgcatg
     1141 gcaagataag gactccgttt aagatgcctg ttgtcaaaga tgataaaaca tcaaatattc
     1201 acatagaata tgaacaggta gaatttgaga taaaagagtg cattgtaagg ttaaatgggg
     1261 aggtggttaa ttccgaagaa tatacaggag agattatcag gggatttcgg atggcttata
     1321 cagaaatact gcaaaatcag aaactcagaa atatgctgaa aacttttttt cagggaaaat
     1381 ccagagtaat tttgcgacat acgcagcaat attatatgta tctgtttgcg tcgttccatc
     1441 cggattatat gaaggaccgg aaacaacgag aggaacttct tcaggtattg cataaaaaag
     1501 gggaaaccca gttgcagaaa gaattaagag attatgaaat acagagcctg ctggaactgg
     1561 atattccata ttttgaaatt gacggaaaca gcagatcaat ttttgatgga aatggaaaag
     1621 aatatcaggg atatctgcca tgtacacctt atgaatcatg gatagagcat atgaagcaat
     1681 tgagttgtca ggatatggag caacaatgtg attacatacg attgtctatg ggattattaa
     1741 atcatgggta tatcggcgaa aaaaatccgc gatgggcaga tgaaaatact tgtatacatc
     1801 aaattgcaga gtggatttgc agaacagctg taattgacgg agctgatatt ggatgggctg
     1861 gactgcattt ctgggataat ggatattgga gcctgaaacc atgtggtatg tatttatatg
     1921 atgggattgc ggggattgtt ttgtttctgg caaaatatct ggaccggtat caggattcgt
     1981 catgcaggca agacgtggaa aaaatctata aactggctat tgaaaaatta gaaaaatata
     2041 cagatctgcg atgtgaacaa aatgaagtac ctgaaccatt ggcaacagga ctttacgatg
     2101 gagagagttc aattgtatat gtttatctga tattatatga gatcacaggt caggaaaaat
     2161 ggatcaagaa tgctcagaag cattttgaga tagtagctaa actgcttcca aaggatgaaa
     2221 atatggatta tctcagtgga aatgcaggcg caatcgtggc tgccatgaaa ctttatcaat
     2281 taactggaga gattgaatat tgtacagctg cggtagaaac tgaaaaagat ttatggaaaa
     2341 aaggtcagag aatggaagtg ggatatggat ggaaactgaa aaatctgaaa tatccgctga
     2401 gtggactttc tcatggaaac agtggctttt tgatggcgta tgtggaactt tataaaatga
     2461 catatgacca ggaatatctg aaaaaaataa aattgttgct ttcctatgag gatatcttat
     2521 attcagaaga cttgaaaaac tggatagatc tgcgtgatcc ggacggacga aagacaatgc
     2581 gtggatggtg ccatggtgct cctgggattt tacttagccg tatgtcgata atggatattc
     2641 tgccagatga taaacagatt aaaaaggata tcctgcgggc agtatccaca ttatttcaca
     2701 atgagcgtga gaaaaaaata tgtctgtgcc atggaatgac aggaaatctt ttaattatga
     2761 aaaagtatct ggagaagaat ccggatgatg atttaagaca gaaatacgaa aggcagtttt
     2821 cgaacctgaa ggaacaattg caagatatga gaagtcttat ggttactgag acattaaatc
     2881 ctgcatttat gaatggaata accggagttg gaatggcaat gatgttgctg aacatggatt
     2941 agaaaaggca tttacagcct ttctaatcag gatgtctgaa aaaataagtt tttaacagtt
     3001 tctttttctg acgattaatg tattgacggg agacatgaag aattgatgca atttcggaat
     3061 ctgttttata ctggtagaaa aacagagaca gaattttgta ttccatactt tggacaggaa
     3121 agctttcgat atatgtagtt atatcataaa gagtttcatc gaatggatta tctgcctgta
     3181 aagtaagaga acacgtatca aagtcttctc tttcaggttc tgacaaatgg tatctgcata
     3241 aagctctgta acgattttct atagcggtct gcatatatct gacacattca ccttcggaaa
     3301 aatttttgcc gttcaggtaa ggcagtgtat taagcagagt cagatacaat tcctgtgtgg
     3361 catcgtcccg ttccatacag tggatgcggg aagcgtagct tttgatcaga ggttccatac
     3421 gtttaagaat ttcttcacct gcatttttga caccagaatg ataatcgtga attaactgta
     3481 ataatgactt cataagaaac tacctccttt ttggaggaag tagtcagaag tgactaaatc
     3541 agaaactgaa aatagaaaaa atatgaattt attgtagaaa aataaaagaa gcgaagtctg
     3601 acaacagaag aaataagctt ctaaaaggaa ttgagttgac aaattatgag attttctgtc
     3661 tttctcagag gaactgaaat gttttactac tgagaaagga ggtatgaaga tatggaatcc
     3721 acggttatgg aaactgcaat atcgcaggga atctgggccg tcctggcagt ttttcttttg
     3781 atttacattg taaaatccaa tgaacaaagg gatgcaaagc aggaagaaag ggaaaaaaat
     3841 taccagacag tgattgagaa tttgactgaa aaattccaaa ttctaaatca ggttcagaat
     3901 gatctgaaag agattaagga taatcttctt aataaaaatt aaataggaaa aagaaataga
     3961 agctctctct acaaaatgaa tgtcacagta gggagggctt ttgtcattca ggtaagaaaa
     4021 cagattaatt caatatacag gcaaaacact catatccatt agaatacatt ttattccaga
     4081 attacagagg tttatataaa tggtgatata ctatgataat aaatattatt gaatggagga
     4141 aaaagagatg aaagaataca aggttataac agcacttttt ttgtcagcag taatgctggg
     4201 tacagctcca ttaaccgtat ggggagcgga gagtttttcg acaggggaat ctttcagtga
     4261 tggaacagaa aatattcctg acatagtaac agattcggct ctgtctggtg aatcttctga
     4321 aagagactat gagttaagca tagaaacagg tacggatgta gagcttacag aaagtgattt
     4381 ttatgatccg gaatttcgtg tagagaaata tgtgaaagtc agaaattcag gaaaaaaaga
     4441 aacaagagtc cgggtagatg cttctggtct taagaatttt gaggtagatg atcagatggc
     4501 aaagtggtca gaggattatg aggaacagga ttccaaaaga ctgctgaagc cgggagaaac
     4561 tctggatttt tttgtactgc caaagcagga atacggaaca tatgatgaaa cgtttgattt
     4621 ccttgcagat gacggaagca gatatccggt tcatatcaca atgaatagag agaagaaccc
     4681 aacggaaaag aagagtctgg aaattaccga aaaatcttcc gagagtttcc cgataatgca
     4741 ctggggatat aagacacttc cggaagccag aatttatgtt ttgaaaaatt ttacggacat
     4801 ggatatggaa ctgtctttcg attatagcaa agactgtagt gtatcattat gcggaaatac
     4861 cagtctggca cctggagaga gtacagaact gagcctttgt ccgcagatgg gactgccagt
     4921 tggagaacat gatcttggag tgacagtgac tgcgaaaaca gcgacaggag agactataac
     4981 aaagaagatt tgggattctt tcagagtaga ttcaaggaca tttcagggac tggtggatac
     5041 cattgaacct gtgaccggaa ttaccaatgg cgtagaaaaa actgctgatg ctttacattt
     5101 gccatcggtt cttaaagtct atggtgctga agtggatgga gaaaaaacga cattttctgc
     5161 cgatgtaaaa tgggatgtgg agaattgtgc atataacccg aaaaatacgg cgtctcaaag
     5221 tttcacagtt aacggacaat tggaactgcg tgaaggtgaa aacaatgaag agctggatac
     5281 gtctgtaaag ataaaggtac aggtggatgc gtacaagggg ttgaacagac cggtgattga
     5341 ttcgacatgg accagagtga tcacgaatta tgcagaactt tctttaagag atacttctaa
     5401 tgaagcagac ggatattttt ttgtagcagc agaatctcaa aaggaactgg aaaaagaaaa
     5461 ttatatcgca caggtgaagg tcgcaaaatc tgaactgaat cattatccta aactgaaata
     5521 tattcctgaa gggacgcatt atctctattg cagggcatat aaagaggaaa gtggtcatac
     5581 ggagaaatat ggtgaatggt ctgaaggatt tctgttaaag gtaaatataa agacaccaaa
     5641 tgcacctgtg gttcaaaaac tacaggtgaa gaaaaatgac gttaaaatta tccttggcag
     5701 taatacagaa gaactggatg gttatgatgt tgttgctgcc agaagtaaag acggggatga
     5761 gccatcagat tatataaagg tacaatgcaa atattcagga aacagcaagg aactcattct
     5821 aaaaggagta ccgaaaggaa actggtatat tggtgtacat ggctataaat atctggatgg
     5881 atcaaataaa aaagtactga gtaagtgggc ggaagttcaa aaagtaacgg taaagacaag
     5941 ccttgtaaca ggaaaaccag ctgttaaatc ggcaaaggtt tccagacagg gaacaaaaag
     6001 aaaagtaacg gtgaagttta ctgtaccaaa agcctgtgac ggaacggact gggtactggc
     6061 aaagaaagta tctcaatccg aagatggaag ttatacatat gtcagcggtt atgcttatac
     6121 taagaaaaat cagacgaaaa ctacagtcat ttttaaaaat gtaaaacctg gagtttatta
     6181 tcttacagga cgtgcttatg taaaaggata tgcaaaaaat tatacgaaat ggtcagaggt
     6241 aaagaaagta gttgtgaagt agaaaagtga tttagaccag aaatttattt tttttctgca
     6301 tatatatatc aaaaaagaag gtgttgtttg tcagaataaa taatccaaag gaagtatggt
     6361 agtatttatt ctgcaactgt gtggtataac caaaacctga gtttacgact gtgaatgtac
     6421 attctgcatc agattctttc cagtttacaa cactgaaagt taatgtttct ggcataattt
     6481 ttgtctcctt taaatttttt gaatttgcaa attcactata taaagatgct gctttggtga
     6541 tttgtaaacc ataagtgtgt atatgagcat gatttttttc tttcatgcgg aaattaggta
     6601 agaataaaaa taaagattcg aggtcagatg atgcaggttt attccctttt tatattttct
     6661 gcatcagttt actgtaaaat aataacgggt aaagaagata taagatgttc tggtacatac
     6721 aattaagaag aaaggggcat gtactgtgta tagtcaaaat gatgaaccgc ctgagatgat
     6781 caggcggttt tgaagtatct ggatttttta tgaatatttt atttttaatt acaggtataa
     6841 tgtgttacaa taaatataac cattaagact accaggcagg tcagaatttg acctgcctgt
     6901 aaataaatac ggaaataaat cggggtcaaa agaatcgtta ataattgtaa caaaataaaa
     6961 ttaccggtgt agcaaaaata aaattacagg ggaaatgcgg atgagtgaga tgacagatgc
     7021 atatgtaaaa ctggataagg tttccaagat atatggaaca aaggaagtaa agatcgttgc
     7081 agtagatgag atcagctttg agattgccaa gggagagttc gtagtgatcg ttggtcccag
     7141 cggtgcgggc aagacgacag tgctgaacat tcttgggggt atggatcagg ctaccagcgg
     7201 agaagttctg gtggatggaa ggaatattgc cagatataac agcaggcagc ttaccggtta
     7261 tcggagaaat gatattggat ttgtattcca gttctataat ctggtgccta atcttacagc
     7321 gctggagaac gtagaactgg cattgcagat ctgtaaaaat ccgctggatg ccagggaggt
     7381 tctggaggaa gtgggactga aggacagact gaccaatttc ccggcacagc tttccggtgg
     7441 tgagcagcag agagtttcca ttgccagggc actggcgaag aatcccaagc tcttactgtg
     7501 tgatgagcct acaggtgcac tggactacca gactggtaag gcaatcttaa agcttttgca
     7561 ggatatgtgc agggagcgtg gaatgacagt gatcgtcatt acccataact cggcgctgac
     7621 acctatggca gaccgtgtga tcaagatcaa gaacggcaag gtttccagga tgacgatgaa
     7681 tgaccatcct acacccatag aggagattga atggtaggtg atgaatatga aagcaatgca
     7741 taaagatttc tggatggaga tacacaaaag caaagctaga tttatttcca tatttatgat
     7801 cgttgctctg ggagttgcgt ttttctccgg gatacaggcc tcgtcaccgg atatgcgctt
     7861 ctcgggtgat gcctattatg atgaaaccaa tcttatggat atcaaagtag tgggaactct
     7921 gggactgacg gaggatgatg tagctgccat caggaaggtg gacggagtag agaatgcaga
     7981 gggcgcctat ggtacagatg taatgtgtgg agaaggcgag aagcagaagg tacttcatgt
     8041 ggaagctgtg gatcaaacca tgaaccggat ctcagttaca gagggaaaag ctccggaaaa
     8101 aagtggggag attttccttg attgtatttt tgctgagagc aatggatatg aggtgggcga
     8161 tcagattacc ctgaaagagg gcggagacag cgaactgctg aaaaagacag attacacagt
     8221 tgtaggttta ggcgagagtc ctctctacat atcttataat cggggaaact ctactctggg
     8281 ttctggtgag gttaatggat ttgcttatgt gttccctgag gattttgacc aggaggttta
     8341 tacacagatc tatgtgcagg ctcatggggc acaggatctg atcagctata cagatgctta
     8401 tgattccctg atagagcgag tgcaggagcg agtggagggg attgaggcag aacggtgtca
     8461 ggtcagatat gatgagattg tagaggaagc caatgacaag cttgcagatg ccagacagga
     8521 acttgaagac ggaaagaagg aagctgatga gaagcttgcg gatgccagac aggaactgga
     8581 ggacggcaaa aagaagttaa aagacggcaa gaaggaatat aaggatggca agaaaaagct
     8641 tgcagacgca aaaaaggaac tggaggacgg aaaagcccgg cttgcagatg caaagaagga
     8701 attagaggat ggcagatccc agcttgccag tgcgaaagag cagcttgcca gtggcagaga
     8761 gcagattgca tctgcaaagg aacagctgaa tgcaggatgg gcggaggttt ccgaaaacca
     8821 ggcaaagctt gatgatggaa aggcgcagct agaggatggc aagaatcagc taagcgccgg
     8881 tgagaagcag gttgcggatg caaagacgca gcttacccag agccagcagg aacttgacaa
     8941 tggaaaggcg cagatccagt caggcagaga gcagattgca gcaaccagac aggacttaaa
     9001 tgccaaaaag gaaagctgca atcagggact tgcgcagatt gagcagcagg aggccgaact
     9061 tgcagaagga gaggctcagc ttgagggtgc cagaagtcag cttgcagcat tgcaggcaca
     9121 gtatgagcag gcacaagctt caggcacata ttccgaggaa gacctggcgg ctctggcagc
     9181 acagatttcc gcttatcagg agcaggtgga cagtcaggca gcccagctgg aagcatccag
     9241 aaaccagatc gcagcagcaa gaagtgaact ggagagtggt ttaagccagg tggagagcgg
     9301 actggcccag cttgatgcaa aggaagcaga actgaaccag caggaggccg catttcccga
     9361 tgcccaggca aagattgatg caggatggaa agaggtgaag gctcaggaga agaagctgga
     9421 accagccaga aaagagattc aggaaaaaga agcccagctt gagtcagcac aggaacagat
     9481 cgatgctgca aaagcaaaac taaattctgg ccaggctcag ttagaggaga agggggcaga
     9541 acttgcttcg ggagaagcac agatccggga gaatgaaggg aagcttgctt ccggcgagaa
     9601 agagattgcc gacaatgaac agaagctgag ggatggagag aaggaaatct cagagaacga
     9661 acagaagctg aaggattcca gaaaggacat caaaaaagct gagaaggatc tggaagaagg
     9721 taaaaaagaa tacgaagacg gcaagaggga tgcagagaaa gaaattgcag acggtgagaa
     9781 gaagattcag gatgcccagg atgagatcga tgatatcagt atgccggaat ggatggtaac
     9841 ggaccgcaat gatctgccgg aatattcaga ttatggggat aatgcagaca gaatgagaag
     9901 tatcggacag gttttccctg ttatcttttt cctggtggct gcactggtaa gtctgactac
     9961 catgacacga atggtggaag aacagagaac ccagatcggt acaatgaagg cgttgggata
    10021 tggcaagtat gcgattgcat ccaaatatct gctgtatgcc tttcttgcca ctgtgggagg
    10081 cagtattctg ggaattctga tcggagagaa gatcctgcct ttggttatta ttaacgggta
    10141 tggcattatg tacaagggca tgatgaacaa tatccagatc cgttatgagt ttaaatttgc
    10201 aatgatagca gcaggtgcgg caactgtgtg taccgtcgga tccaccattt tctcctgtta
    10261 cagggcactg gcggaaaccc cggcatcact gatgcgtcct cctgctccta aggagggtaa
    10321 gagaatcctg ctggaacgga tcccgctttt ctggaagcat ctgaatttta catggaaatc
    10381 tacactgaga aatcttttcc gatataaaaa acgtttcttt atgacgattt tcggtatttc
    10441 aggaagtatg gcgctgatgc tggtaggctt tggactcagg gattctatta tggatattgc
    10501 cagacggcag tatcaggagc ttcagcatta tacaggaacg atcattgatg atgaggaggc
    10561 aacagataag gagagacagg agctggatga gtttctggaa aataacagtc agattgagag
    10621 atatactcat gtccagttta ccaagatgag tgttcccaga aataaatcca atatcagcgt
    10681 atatgtctat gtgcctgaga atcttgggac ctttaataag gatgtaacac ttcaggacag
    10741 aaagacaaaa gagaaatata agctgacaga tgcaggtaca gtgatcagtg agaagacggc
    10801 atctctgaca ggactgaagg tcggggatac catgaccatc acaaaggatg ggaaaaatta
    10861 tgagacaaag atcgcagcag tgacagagaa ttacatggga cattatattt atatgacagg
    10921 aaatgtctat gaacagacct tcggggagaa gccgaactat tctgcaactg tgttcacggt
    10981 aaaagaggag tacaaagaat cagaatctga ggtgggaaat gaaatcctga agcatccggc
    11041 tgcgttaagt atcagctata ccagcagtct ggaggcccag cttcacagaa tgctgggagc
    11101 attggatacg gtgataatag tgctgatcat ttctgcggga atgcttgctt tcgtggttct
    11161 gtataatctg aacaatgtca atatcacgga gcgccagaga gaactggcaa ctctgaaggt
    11221 gctgggattc tatgatactg aggtttctgc ttatgtatac agggagaatg ttattcttac
    11281 cttcataggt gtgctggcag gggctgtatt cggaatcatt ttgcacaggt atattatccg
    11341 tactgtggaa gtggatgcgg ttatgttcgg aagaaatatt aatcctgtca gtttcctgta
    11401 ctgcggactg ctgacaattg gattctccat gatcgtaaat ctgtttatgc atcagaaatt
    11461 aaagaagatt gatatggtag aatccctgaa aagtgtggaa taaacgatct gtcgctttat
    11521 tgcggaaaag aagaaattgt ttttctgtgg tttttaaata tgtagtcaaa cggatagaat
    11581 ggataagagg aagaaagggg aatattatca tgggaacagc aaatcagata gagcaggaat
    11641 taatgaacta tatatccgat cataaaatca ggaacacgca ttcacatcat ctgccggaac
    11701 aggcgatggt ggattttgat ctggataagc tgataaataa tacgtattta caatggcagc
    11761 aggtaactcc ggggacaaca gcagaaagca ggaatgcata tctggaaaaa acacgatata
    11821 aatcttattt tgtctggctt caaaaggcaa tcggggagtt gtatggaata tcggagccga
    11881 tcacagctca gaactgggat cagatttcag atcgaatcag aaaagcgcat caaaatcccg
    11941 acttttacat ggatgtgctg aaaaataagt gtaagtatca aaaagtaatc gtagatacct
    12001 actggaatcc gggctctgac aatggaagac cggaactgtt tacgcctgct tttcgactgg
    12061 atctgttctt tttgggctat aaaaaaggac ttcgcaatca tgacggtgta tcactggaag
    12121 agaacttcgg tgagctgccg gacaatttac aggattatgt ggagtgggtc agaaagtgga
    12181 tcatacaaaa aaagagtgag ggctgtgtgg ccttaaaaat agcgatggcc tatgagcgta
    12241 gtcttcattt tgaaaaagtg acgcgggagc aggctgaaag ggtattccgt ttaaaagagt
    12301 cggatataac ccaggaagat atcagatgtt ttcaggacta tttgttctgg aaaatatgtg
    12361 aaattgcggc ggaagtgtca cttccattac aatgtcacac aggaatgggg caagttatag
    12421 atacgaatat actgcagttg aacaatgtga taaaaaataa tccggaaacg aaatttgtgc
    12481 tactgcattg tggctttcca tgggtggatg atcttttttc catagtagac ggatatccga
    12541 atctatatcc ggatctgaca tggcttccaa tcttatccta caccgcatca aaacgtgtaa
    12601 tgcatcagtt gatcgagatg tcccagattg ataaaatctg ctggggatgt gatacgtgga
    12661 cagtagagga aagttatggc tcccttcttg cattccgttt ttcactgtgt agtgttctga
    12721 gagaaaaaat agaggacgga tatctttccg taaataatgc aaaggatatt attgataaaa
    12781 ttttgttcga caatgcggga aaaatatacg tatgacatca gataaatttg tgaaaaccgg
    12841 agaaacgttc ttgacaagaa agcctttttt cattatagta gaatccagaa aaaggctgtg
    12901 aaaaagagga gtaggcggta atgccccaca gagagggaag ct
//
