LOCUS       c00040_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJBMFBIC_83.
ACCESSION   c00040_gnlPro..
VERSION     c00040_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 02:27:11
            Original ID  :: gnl|Prokka|JJBMFBIC_83
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 7857
            Orig. end    :: 31106
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[17857:21106]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(52..1143)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_10"
                     /sec_met_domain="Peripla_BP_3 (E-value: 1.6e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCKKIL"
     CDS             complement(1335..2222)
                     /locus_tag="ctg40_11"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSKS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             complement(2219..6916)
                     /locus_tag="ctg40_12"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDRVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLRSFVVQDILEDC
                     LTIEDASKISIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQLLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASAASNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARSVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVAEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLNVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGETETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEVVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEVYVKTKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGNGGSSYGNSGGYGSYQGGSMAGSS
                     KTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKDMPRK"
     CDS             complement(7118..7579)
                     /locus_tag="ctg40_13"
                     /transl_table=11
                     /translation="MNRKEFLEILRGQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIILLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             complement(7765..7878)
                     /locus_tag="ctg40_14"
                     /transl_table=11
                     /translation="MSLVIVHTPLSREVFWHEYAKIPRHTSQNSIAAGNLE"
     CDS             complement(7882..8760)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_15"
                     /sec_met_domain="CN_hydrolase (E-value: 3.3e-56, bitscore:
                     181.4, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             complement(8863..10053)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_16"
                     /sec_met_domain="PAD_porph (E-value: 1.4e-127, bitscore:
                     416.3, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRLSDISDTKTLRAGFPDICRAIKEKETDMEVTEKNRTKYRMPGE
                     FEPHEGCVMIWPERPGSWNYGAREAQKAFVKVAEAIGVSEKVYMLVSKAQMENAKNQLG
                     NVSGVTLLECETDDAWARDVGATMVLDEKGAVCGVDWQFNAWGGDFDGLYRNWEKDDRV
                     AAFICRTVGCPCLDARPFVLEGGSIHSDGEGTLIVTEACLLSQGRNPQMSREQIEEQLK
                     YWLGVHKIIWLPCGIYQDETNEHVDNVCAFVRPGEVVLAWTEDETDPQYAMSLADLKVL
                     EQETDAKGRKFKIHKLPIPQKPVCLTREDVDGFVFEEGEDERKAGERMAASYVNFYISN
                     GGIILPQFGDENDKRAVEILQKCFPERRIYPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             complement(10001..11122)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_17"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 6e-15, bitscore:
                     46.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKDVCTRASLGLRINPECSTQGDHAIYNPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             complement(11112..12392)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_18"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.2e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 9.8e-36,
                     bitscore: 113.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKIDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             complement(12389..13249)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_19"
                     /sec_met_domain="Spermine_synth (E-value: 9.4e-54,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 1.4e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             complement(13252..14709)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_20"
                     /sec_met_domain="OKR_DC_1_C (E-value: 7.4e-14, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 1.7e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEYLQVLKGGI"
     CDS             15935..17620
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_21"
                     /sec_met_domain="FTHFS (E-value: 1.3e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             complement(17729..19153)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_22"
                     /sec_met_domain="Lyase_1 (E-value: 7e-95, bitscore: 308.9,
                     seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 2.6e-22, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             19269..20204
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg40_23"
                     /sec_met_domain="LysR_substrate (E-value: 9.7e-34,
                     bitscore: 107.5, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.1e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFERYIYQKEQ
                     LLLAVPKNYSVNTRLQKYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             complement(20316..21773)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_24"
                     /sec_met_domain="FGGY_C (E-value: 1.2e-37, bitscore: 120.6,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 1.3e-80, bitscore: 261.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARGLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
ORIGIN
        1 atgataaaat tcctcctgga tttattttta ttttttattt atttcatttg tttacaatat
       61 ttttttgcat gatccccgta tgatcagttc cggataaatc agtctttcaa ccttactttc
      121 ttcttcagga actccgttga tcttctcaag tataagctct gctgccattt ctcccagctt
      181 ttcctgcgga tgagctatcg ttgtgattcc gcttcctcgc tgagcataca gtgaattgtc
      241 ataaccggta atggaaatat catccggtat cctgactccc attttctcca gttcttccat
      301 aacctgaaca gcaatctgat cattgtaaca aacgattcca tccggaagct gtccgctctg
      361 taccatttct tttgccatca gtgcaggttt tactttcctg tcctctgtat gaaaccagac
      421 aacatcatca ggatcatagg caatccctga ctcctgtaag gccttcacat atcccttgtg
      481 gcgctccagt ccctgcatat cgtctgcctt aaagaaaccc ttgatctttt tatgtcccag
      541 ttccagcaga tattttgtta caagatagcc tccctgtgca tcatccataa gaatatgagg
      601 tttatccctc atttctgaat agattccctg aataaacaca tacggaattt caaatttatc
      661 cagattctga taaagatttc tgtgtttaca gatcatctca cttttgcttg gttcaatgat
      721 cagtccatca atatctttct tcagaagttc ctccagacat ctggcctctt tctgtctgct
      781 gtttgctgtg tttttcagga taatactgta accgctttct gaaaggacat tatccattcc
      841 ctgtatcagt ctcggaaaaa tataatcaga aatatatgtg gtcactaccg caatattctt
      901 tgaattcttt atatggcgca tattctcaga gcaataagta cctcttccgt gaaatgcctc
      961 tacatatccg tcctgctcca ggattcccag tgctttacga actgtatgtc tactcaggga
     1021 atatttctgt gaaagctcgt tttctgaagg aagcttctct cccggtcgga tagctcctga
     1081 cataatatca cttctgagct gttccatcag tgagaaatat ttcggctttc cattatctgt
     1141 catgtcttct tccctcctgt atttaggata caacttgtac gcacgtacga acaagttgtt
     1201 ttttatgcat aaattataca aaatatcgag agatttttca ttagtttttt ccaaaacacc
     1261 tcgagggata gtgatatgtg aacagtaaca gttcatcctt tacgaaagtt accaatatcc
     1321 gattgatttc aacatcactt cggctcagct ttttctatac cataacattc atggcaaatc
     1381 ccatgtaccg ccatacgtat ttctttatcc agacgtgaat tacaggtgat cagagtcacc
     1441 attctctccc tttcatcagg ctctactcct gtgtcataca tggaattatt tttcaatata
     1501 gataattgtc tcctgtatgc aggactggat aacttgtatc catattcaaa tgccgggctt
     1561 ttggaagatg cctgttccac agaaaaaatt ttgtacagaa actttctttt tggtgttgtg
     1621 atctcaattt caggacattt tttcagaaat tcaggctgtt cataacggtt cagatttgca
     1681 aacatcatat taccttctat attatgcccg taaagaatac tgtgggaatc tgtaaaattc
     1741 ttttttatgt catgttccag aaaaatacat ccaaacagat cttcctctcc tctgaaatta
     1801 tgtttcaggt aatattcatc atctgccgcc tgaactacag gataagaaat atcggctccc
     1861 gggacagtaa tccaggcaac tgtctgagag ttgatctttc ttaaattttc ccaggaaatc
     1921 ccgaaggatt ccctgatttc atctgtacag tttttgtttt ttgattcaga agatcttctc
     1981 tgttttttcc tgcgtttttt ttcactgttt tttgtactac tgtcttcatc agtttttttg
     2041 ccatctgcca ataatccggc accttctctg ttcttcaccc ctgccatttg ggaaagctct
     2101 gcatattcct gccttgctgc aagattctgt tcataacttt ttatatagaa gccggcacaa
     2161 tatataagaa gcccaattgc tgctatgatc atacttactg caaatgttct gagttttttc
     2221 atttccgcgg catatccttt atatttcttt tcccggaaac agttcttctg tagatcacca
     2281 cacctcctgt cagcagtccc attccgataa gtccaagaac agccatcatt ttaaacggtc
     2341 tgacatctcc tgttttagaa cttcctgcca tggaaccacc ctgatagctt ccgtatccac
     2401 ccgaatttcc gtaactgctg cctccgtttc cggaagttgt gcctccatta tttccaccat
     2461 tgtaagatgc caacggtgct ttcgtcggta caggagtcat tttcgggcag gttcccggta
     2521 cagatggtgt tggtgtggct tttggctgct ccgtcggttt cggtacttct gtaggttttg
     2581 gtgtctctgt cggctttggt gtttctgttg gtttcggtgt tgcagacggt gttggtgtgg
     2641 cagtgggttc tgcttttgtt ttcacatata cctcctgctg cgcagtaatt tccggtgaaa
     2701 tatctcctct tgctttcgct gtgtttacaa ttttttcagg ctctgtgctt tctgttttaa
     2761 ataccacttc atagcagact tcaattttat ccatatctga caacgatgct cctgtctgaa
     2821 ttacaaatcc tgtatcatct gcctctattt tggcatcttt cagctctatg ccgtttttct
     2881 tcacaaaaat gctgtctttt acaatagaag ccccttgggt ttccagttta tcttcgataa
     2941 caatattctg atctgtgaca tcctcacgca gttgtcttac tgtcagctta tagtatcctt
     3001 tctcaccgga cgcatactct ttcttatctg attccttcac aatttccaga atcgggctgt
     3061 gtacctctgt ctctgtttcc ccggttgcag gtatcttttc actgctgtct gcaactgcag
     3121 tattgtgcac tttctgtcct gccagggctg catcaatcac tgctgcctga tattccacga
     3181 tcatactttt ctgttcctga cagtccagag gattatacat tacctgctca aaaagaccgc
     3241 ctttatcatt atcgcagata ctatatctgc tgtccctgac cagtgtcctg cctgttgaca
     3301 tcaggaaagt attatcatca ttgatctgta catcagcatc tgccacattt cctttctcat
     3361 ccatcagaat caccgaatcc ttcagaagac gtactccctg agtatcgatc acatcctgca
     3421 gagtaacatt acgcgccaca catccggtct gctcctgtgt caggacaatg cggtatgtaa
     3481 taatatcacc atatttgtaa aatggtttgt ccgtcgtctt ctctacgtta agaacaggcg
     3541 agttcaccca gatttttgag gagtccttta ctttctgtgc attatctgca tacgcctgtg
     3601 ctgtatttac aatctccatc ccatttacgc tttcctgcgc agtacagcgg aaattaacag
     3661 tcacaggtgt ctgatacgga agatctgaaa tcgtcacgat ccatccggtt ccctgacgtg
     3721 taacctgaca gctgaccggt ttttccactg tttctttata attttccgga ttcagctgat
     3781 ttcctgcatc atcagttcct gccaccggat tctgaataac agccggaaca ccgcttacag
     3841 taacagcatc ttcagctccg tccagagcca gcccttcagg aagggaaaga tcactgatca
     3901 caagatttct tgcgatagat cccttctgaa gattattaac cgtaacctga taattcacct
     3961 gttctcctac ccgaaattca ttttccgcac gtccgtcccc ggctgccaga tatggattct
     4021 gaaaactttt ctcaatagaa agaactgctg tatttacata cacttctgcg tcatcctgtg
     4081 aaacaggggc attctgcgcc tgcacattgg caacattaat gctttccatt ccatttgccg
     4141 cttccgcaac tgtgcaaagg aaagaaatca taaccggagt atttgccgga agatctgaaa
     4201 tgttcagtct ccatccgctt ccctcctgaa gaaattcata attcaccggt ttctctgatg
     4261 tctcattata aaattccgga ttgagctggt tcaaaacatc tttggtccct gctgtcagct
     4321 gcgtaatatt ctgtggaatt ccgcttaccg atacatcctc tgccgatgaa agcgcaagtc
     4381 ctgccggcat accggtatcc cagacagtta cgttccgggc cactgtacct gcttttttat
     4441 tctccaccac cacattgtac tgtacctgtt ctccgacctg ccattcataa tgatctgcag
     4501 atttctcaat ccagaattct cctgaattta catatacttc tgcatcatca gatctctcat
     4561 ctgtattagc agcttttaca gttgctgcat ttacgctttc gtgtccattt gcctcttcct
     4621 gtgcgataca atggaaaata atcgttacag gctgactgta tggtacataa gaacaataaa
     4681 aggaaaatcc gttctcatct gcattcaact gagaatccac agatctcgct tcatatgcct
     4741 gtcctgtttt cttatccggt acgggatagt ttacctgttg ctgaactccc agtacttcca
     4801 tgctctgtgc accacctgcc agaaccagtc cctgcggcag accaatatca gtaatagtta
     4861 catcttttgc gattgttcct gccgttacat tattcaccac gatccggtaa gctacctgct
     4921 ctcctgcctg ccattcatat ttgtctgctg ttttatcaat ttcaagctgt ggactgttcg
     4981 gccatacttc tgccatatcc tttctggatt cctgttctcc cgtctcagga ttgatcagat
     5041 tatccgctgt tgcagtcaca atattttccc attcctgtcc attggaagcc gcagatgcct
     5101 gacatttaaa acggattgtg atcgtctccc catacttcag ggacggacac tctgctttcc
     5161 atccattttc tccctgtccg gtaagcgtac agttctcacc tccctgactt gtctctacag
     5221 catactgccc ttccagaagc tgcagacatg atggaagctc atctgtaata acaacattta
     5281 ctgcttttac atcctgtttt gtctgagaaa ccagaacctc ataatctatg atatctcccg
     5341 ttttccattc atactgagaa gtatttttct ttacttccag ttccggtgga atcacaccct
     5401 ttacccacac tgtttccgta tccattgtat ctccgcttcc gtttgtacgt tcataactca
     5461 tggatgcatg gtttggtaca agaatactgt acccatcctc tgcaaggtat tttgaaatgt
     5521 taatttctga ttccggtctc tggcgtactt ttaaagtaaa tgtgtaagtc tgattatctg
     5581 taaatgcttc atcctgaagg ctctctgctt tggccctgca ggtcactttc tgtccttcaa
     5641 cagcaacatc aaaccagtct gtcactgtct gccctgcatc attcacaata ctgatttttg
     5701 atgcatcctc tatagtaaga caatcctcaa gtatatcctg taccacaaag gatctcagtc
     5761 tattgggtgt cacctccgcc cggatcatat actgaaattc ctgtccctga cgaatgccaa
     5821 aaggtttttc ttttgatgcg gcagctgcct gttcccatgt acagtttgcc tctcccacac
     5881 gtttctcagg cgcttttttc atctcaacat caccgaaaca ataggatgta aaatcaaaat
     5941 atgcatatgc tttacagtat ttctgtcctt taaagttcgg acaataactg ttgcctgatg
     6001 gatccagata tttatttctt gtaatctctg cccatctttc ctgagaaccg gcttttgcaa
     6061 tggcatcttc acgactttta tcccatttat ccagtctgaa ctgatgacag aattctaccg
     6121 taaaattatc tgtattataa aaaagattca gccatcctct cggatcatcc ggctcaacgg
     6181 aaccaagggg tgagcttaca gaatttccat ctaccgtcag ataatcattg tttttcagaa
     6241 catatgcatt atccaggctg ctgtctgacg gaatacggac tccctgtccc gcatcaatat
     6301 cacgtatggt tccatggcca ctgatcggca gtgtttcttc tgttccatgc ttcagaaact
     6361 gaaacttaac ctttgcgtat cctacagaat aaataaatac accgatactg tttttggaaa
     6421 agccaaccat tggataagct tcattatctt tccatgcaaa cgtagctccg cctttattct
     6481 gaacaatcga ttctgcagtg cgcagatcat aacggggttc tgcattctct actcccacaa
     6541 gaatgagtct gacatcaaca atatttccat ttccatcttt tcctacattg ttataacgca
     6601 tccctgcgct tccggcttta tagtccgctc ctacacgaac gcactctgtg tcacgttcac
     6661 tttttccatt gtctgaaaaa gcttccctgt ccagattatc acacccaaaa gattcatatg
     6721 tggtaattcc gggctgaaac ttcatgttaa agcgataacc ataatctacc accctgtcac
     6781 tgtcccatgt ttctacagtt aacggtgccg cctgagttac gcagacaggc acaagcccca
     6841 gaattgcctg cagaataaaa agcattgcaa gcagcaaagc tccaaggcgt tctttcagtt
     6901 tgaaattgtg tttcattttc cgtctccttt ccgaacaaaa aatataaaaa tgaatgtggg
     6961 atttttccct gcaccaggca ggattaaaga atagaaataa gttgaaatgt atgattataa
     7021 atattcaagg ggaattaata tcgtgaaaca agaacgttta cacttaagat tttaagattc
     7081 tgcgcagggt tccttttctg aaaccctgca cagattttca ttgatcattt cttttcttca
     7141 gccatgaaag aaaataaaga ataattgcaa gaataataaa aaacggaatc gcaactccga
     7201 ttatcagtat cagtaaaata attataacag ccgctgctgc aataacaaca gccctgccat
     7261 gccaggtaga aagatcgatt acttttttcc atcttttctc ctgctgatga ggaagctctg
     7321 tctcattgcc ataactgctt ccataagagg aatactctcc gtaatcttcc tgtgtacttc
     7381 catcatctgt atcgatcaga gtttttgcta tcagatgcgg atctcccagt tcctgcagta
     7441 cctcctgctc tgaacgtccg ccacgtacct gagactgtat ataatcttca taatacctga
     7501 tatgtgctgc tgctttgccc tcctgcatct gcccggcaag ctggcctctc aggatttcca
     7561 aaaattcttt tctgttcatc ttctacactc cattttgcca gaaatacata tcaaaactct
     7621 actgctctct ccgttatcag taacgttcgt actcttattt taccatatat accgcaggta
     7681 gcaactaata taatcataaa ctttttatga aattcttata aactcagtta ctgttcactc
     7741 cgttctcagc aactgagcca aaattcattc cagattgcct gcggcaatgg aattttggct
     7801 tgtatgtctc gggattttgg catattcatg ccaaaacacc tcgcgggata gtggtgtgtg
     7861 aacaataact aaactcatac atcatttccc gacaattttt gcatacatct ccggtctgcg
     7921 gtctctgaaa agtccccagt tcagtctatc tgcctttaat gcatccaggt caaaagtgct
     7981 tacaagcacc ccctcttccc ctccgggcag ttctgcacag agagcacctg tgttgtctgt
     8041 gataaaagag gaaccataaa aattaagagc agatttctgc attccatttt ccggacatgg
     8101 ctctactgtt tcctcaccga ttctgttggc agcgatcaca gggatcaggt tggaggcagc
     8161 gtgtccctgc atacatcttc tccagtgttc catgctgtca cattccagga tgggttcact
     8221 tccgatggca gtgggataaa agagaagctc tgcgccctgc agtgccatac atcttgccgt
     8281 ttccgggaac cactgatccc agcagattcc aactccaatg gttccaaatc tggtatcaaa
     8341 aaccttaaag ccggtatctc ccggtgtgaa atagaatttt tcctgataat aatggtcatc
     8401 cggaatatgt gttttccgat aaatgccgag attctttcca tctgcatcca gaaccgcaac
     8461 gctgttataa gtattattga cctctttttc ataaaagctg accggaatca caatccccaa
     8521 ctctgccgct accctgctga aatgacgcac tgcagggttt tcctctgcag tctgcgcata
     8581 ttcataatac tcatatctgc gctcctggca gaaatagggc cgttcaaaaa gctctggaag
     8641 aagaacaatc tcagctccct ttgctgctgc ctgacgcacc agttcctctg catgggcaat
     8701 atttttctcc acacttttac tgcatttcat ctgaactgct gccactgtta catttctcat
     8761 cctgtctgtt cctcctgctc ctgtttacat aagtaagttt tttcataact ttcaggtaat
     8821 acccctcaaa cacatgactc tcaaagtttt tctgcatcaa ggtcagatat tttttccggg
     8881 aatctgctgg gtaatacagt gaatatttcc accgccgaca atgatggctc tggcatcaat
     8941 gggataaatc cttctttcag gaaaacactt ctgcagaatc tccactgccc ttttgtcatt
     9001 ttcatcccca aactgtggaa ggatgatccc accattggaa atatagaaat tcacataact
     9061 ggcagccatc cgttctcctg ctttccgttc gtcttctccc tcttcaaaca caaagccatc
     9121 cacatcttcc cgggtaaggc agaccggttt ctgaggaatc ggaagcttat gaatcttaaa
     9181 ttttctgcct tttgcatctg tttcctgttc cagcaccttc agatcagcca gagacatggc
     9241 atactgcgga tctgtctcat cctctgtcca tgcaagcaca acctctccgg gccttacaaa
     9301 agcgcacacg ttatccacat gctcattggt ttcatcctga tagattccac atggaagcca
     9361 gataatcttg tggacaccga gccagtactt caactgttcc tctatctgtt ccctgctcat
     9421 ctgaggattg cgtccctgac tcagaagaca ggcctctgta acgatcagag tcccctctcc
     9481 gtcagaatgg atggaaccgc cctcaagcac aaaaggtctg gcatccagac atggacaacc
     9541 aacagtcctg cagataaagg cagccaccct gtcgtccttc tcccagttcc ggtaaagtcc
     9601 atcaaagtct cctccccagg cattaaactg ccagtcaact ccacagaccg cccctttctc
     9661 atccagaacc atggttgctc ccacatctct ggcccaggcg tcatctgtct cgcattccag
     9721 caaagtcaca ccggaaacat tcccaagctg attctttgca ttctccatct gagctttgga
     9781 aaccagcata tacacctttt cgctcactcc aatagcctct gcaactttca caaatgcttt
     9841 ctgtgcttcc cttgccccat aattccagga accgggacgt tccggccaga tcatcacaca
     9901 tccctcatga ggctcaaatt ctccgggcat acgatatttt gttctgttct tctctgtaac
     9961 ttccatgtct gtctcctttt ctttgatagc ccggcagata tcaggaaagc cggctcttaa
    10021 agtcttcgta tccgaaatgt ctgataacct cacactctcc gtcctcatgc ataaccgcaa
    10081 tatccggcag cggcataccg ttaaatgtat tattcttcac catagaataa atcgccatat
    10141 ccataaaata cagcttgtcc ccgatccgga tctctctgtc aaaggaataa tctccgatca
    10201 catctcctgc caggcaggtg caggaagata agcggtaggt atatgccttc tcccctgctt
    10261 ccccgctgtc cttaagaggc ggacgatagg gcatctccag cacatccggc atatggcagg
    10321 ctgcagaagc atccagaatc agcgttctga tctcattttc cacaatgtcc ataacctctg
    10381 tcaccagata tccggcattc agggcaacag cctccccggg ctccagataa atatccagat
    10441 cataggtttc cttcatatgc tgaatacatt tttccaggag ctttacatca taatcctctc
    10501 tggtaatatg atgtccgccg cccatattca gccaggaaac ctcagacaga aattctccaa
    10561 acttctcctc tactgcctgc aatgttttct ccaggtcatc tgcattctgt tcgcagagcg
    10621 tatggaaatg cagtccgtcg atccatttca gacattcccc gtcaaagttc tctctggtaa
    10681 cccccagcct ggaacccggc gcacagggat tatagattgc atgatccccc tgagtggagc
    10741 attccggatt aatacggagt cccagactgg ctctggtaca cacatcttta aatttcttca
    10801 gctgtgctgt ggaattaaag ataatatggt cacagatccg atccagttcc tctatatctt
    10861 ctgtacggta agcaggggaa aaaacatgat tctctttccc catctcttca tatccaagcc
    10921 ttgcctcaaa cagaccgctg gcagtggtac ctgccagata ttttccgatc atgggataca
    10981 gagcaaagcc ggaaaacgct ttctgcgcca gaaggatctt acacccggta tcctcctgga
    11041 cttttttcaa aatctccaga ttctcccgca tcttcttctc atcgatcaca tagcagggag
    11101 tttgcagttg atcaatcttc attggctttc cagaccttta ccagttcagg atcttcgcag
    11161 actttccatg gaagtcccca tttgttcagt gcttccatat atggatccgg atcaaattct
    11221 tccacattaa atacacccgg cttcttccac tgtccggtca ctaccatcat ggaaccgatc
    11281 atagccggaa cacctgttgt ataggagatt gcctgggatt ccacctcttt atagcattcc
    11341 tgatgatcac atacattata aatataaata cttttctctt ttccgtcctt aacacctgtg
    11401 aaaatacagc cgatatttgt tttacccact gttctcggac ccagagatgc aggatccggc
    11461 agaagagctt tcaaaaactg gatcggcacg atctcctgtc cattaaattc cacaggtgcg
    11521 gtggaaagca ttcctacatt ttccagacat ttcatatgtg tcagatagct ctgtccgaat
    11581 gtcataaaga aacggatcct ctgtactccc ggaatatttt ttgccagtga ttcaatctct
    11641 tcatgatgaa gaagatacat atccttcttt cctacctcag ggaaatcata gacagattta
    11701 aattccatag gctctgtttc tacccaatgt ccgtcttccc agtaggaacc atttgcggaa
    11761 acctctcgaa gattgatctc cgggttaaag tttgtggcaa aaggatatcc atgatcaccg
    11821 ccgttacagt ccagaatatc aatggtatgg atttcatcaa aataatgctt caaagcatag
    11881 gcactgaata cactggtaac acccggatca aaaccggttc ccagaagagc agtcagtcct
    11941 gcttccttaa atttctcatc ataagcccac tgccaggaat aatcgaaata agcagtaaag
    12001 cctttttctt tacatctctt ttcatagatt gcacgccatg tgggatcttc tgtatcctct
    12061 gcttcataat tggcagtatc aatataatcc gcgccggctt ccagacatgc atccatgatg
    12121 gtaagatcct gatatggaag tgccacattc aggacagcat ccggcttata ggctctgatc
    12181 aattctgcga cctctgctgc attatccgca tctatctttg ctgtctcaat ttttgtcttc
    12241 gttgtacttt caatcttctc tttgagtgca tcgcattttt cctttgtcct gcttgcgatc
    12301 ataatctctg taaaaacatc gctgttctga cagcatttgc gaattgccac tgaagctacc
    12361 ccaccacatc cgattaccaa taatctgctc ataaactgtt ttcctcctct tccagtaaat
    12421 cttctacata ttttggaagc ataaatgctc ctctgtgaag atttgttgta taataccatg
    12481 tttctatatt aagattatca aacctctccg gcctgaaatc ttccagtgga tgatatttct
    12541 ttgatgcaaa tccaaaaagc cagtatcccg agggacaggt agggatatgt gcctgataaa
    12601 ccctgctcac cggaaatgac cggaaaacct ttctgtgcat ctttctgcat tccacctcat
    12661 cctcatcata aaaaggactt ccatgctgat aaaccatgat tccgtcatct ctgagagcct
    12721 tataacagct tccgtagaat tcctttgtaa aaagtccctc tgtatgtccc agcggatctg
    12781 tggaatcatt gatgatcagg tcatatctgg cctttttatt ccgcaggaac cgaaggccgt
    12841 cttcataata aatgttgact ctctcatcct tcagtccctg ggcaatatcc ggaaacatct
    12901 ccgcacatac atccacaaac attttatcgg attccaccac atcaatgctc tcaatctgtg
    12961 gataatggat cagttctctg gcaactccac cgtcaccgcc gccgatgatc agaacatttt
    13021 ttacattggg atgtactgtc attggcacat gcgtgaccat ttcatcataa ataaattcat
    13081 ctttatcaga gaatacgatc tcaccgtcca gagccacaaa tcttccaaat tcttcagact
    13141 caaacacatc gattctctga aattcacttt cccctgaaaa taactgtcgg ttaatccgga
    13201 cagaaagctt tacatttcct gtatggaact cggaatacca taattccatg atcagatacc
    13261 ccctttcaga acctgaaggt attctacctt cggatcctcc attccctgca tggaacagcc
    13321 tttgtctctt gcataaagaa tgtattctac aatttcctgt gtcaccattt ccccaggagc
    13381 aagaatcggg attcccggag gataacacat aacaaattca ccactgatcc tgcctgccgc
    13441 ctgttccatg ggcagagatt ctttctccgc ataaaatgcc tgctgtggag acgccaccac
    13501 tgcaggtgcg atatattccc cggaaagcat acctgtgctg tccttcttat acagacgttc
    13561 aatatcagcc aatgccccta ccagtctctc aatatcctga agcctgtctc cgatggaaat
    13621 gtaagccaga atattacaga tatctccaaa ctcgatctga atatcatatt catctctgag
    13681 aagatcataa acttcaatac ctgccagccc atttcccagt gtataaatag agagttttgt
    13741 aacatcaaaa tcaaaaacac tggttccatt gatcagatcc ataccatatg cataataacc
    13801 gccaatctca ttgatctcct ctctggcata ctgcgccatc cctgcaacct tttcaaagga
    13861 ttcctctccc ctgagtgcca gatttcttct ggagatatcc agactggaca acagaagata
    13921 agaagcgctt gtggtctgag tcagattgat gatctggcgc actttctctg cattcatact
    13981 cttattcaaa agcagcagcg aactctgtgt cagacttccg ccggatttgt gcatggaaac
    14041 tgccgccatg tcagcacctg ccgccattcc ggatacagga aggtttctgc cgaaataaag
    14101 atgggttcca tgagcctcat ctgccagcac cttcattcct cttgcatgag ccttctttac
    14161 gatggtccgc agatccgaac agattccata ataggtaggg ttatttacaa gaactgccac
    14221 cgcatccgga ttctcatcca tagccttctc cacctgactg acttccatgc caagggaaat
    14281 gcccagctgc gcattcacct ccgggtttac ataaaccgga attgcaccgc acagtaccag
    14341 ggcattgatg gcacttttat gtacatttcg cggcagaatg atcttatccc ctgccttgca
    14401 gacagacagg atcatgctct gcactgcaga tgtggttcct cctaccataa ggaatgcatg
    14461 cgctgcgcca aaagcatctg ctgcaagctc ctccgcttct ctgatcaccg aaaccgggtg
    14521 gcagagattg tccagcggct tcatagaatt aacatccagc cccacacatt tctctcccag
    14581 caactgtgca agctccggat ttcctcttcc tcttttatgt cccggcacat caaagggaac
    14641 gactctcttc tttcggaaac gttccagtgc ttcatatatg ggcgcatgct gttgtctttc
    14701 ataatccatt tgacatgttc ctcttttcct gtcgtcatgt accggcaaat acagttctat
    14761 cattcagcaa ttgtatactg cctcaaaccg gcacaatgat tcaattattt ctctatatat
    14821 ttgctatatc tgcacaaaaa aagaagcaga taagttcatt caccatctgc ttctctcatg
    14881 atctatagaa tttctcaggc tctgtctctt tatatactga ccggatttcc cgtataaatc
    14941 cgtctgtatc ctgtgcctgt tcccgtattc tgaaatattc atgactgctg tcgtcttcaa
    15001 tcgctggcaa atatatgcta tgctcttatt gaccgtttca caagatgatg tgtgcttacg
    15061 cactgattat tataaagtaa tcaacttata aaatttgagc ttctaactca atcaataatg
    15121 tggtgtctcc cacccggcaa ctgccccgcc tgtccgtatg gcttaacatt cagaaactgt
    15181 ctctgaatgt gagcaaatat ttgcatgaaa acgatagtgt cttttcatac taaagatgag
    15241 aataacatat cttctgaact gttgtcaatt ccattttcca tattttgcac tagagcgtgt
    15301 ctgaaaaagg ctttctgcaa gatgtgcgtc acaatttgtg ggatattttg cccggatgag
    15361 ggcgccgtag cgggctacgg caactgaatt cgggtgaaat atcccgcaaa gtgggggcgt
    15421 acagattgcg ggaatgattt ttcagacacg ctctagcttt acccgctttt tatattttct
    15481 tcatttatca gggaaaactg tgtttatttt ttaacaattt ctttccttga gaaaacgtat
    15541 tttctttcat taccagggat tacgattctc ttctcttatc aatttgcaca acttttatcc
    15601 agtttgctca cattttttga cgtttcagca aaaattttct tgacattttt ttctcaaaat
    15661 gatatattgt attcatcaat tgaaagaacc ttcgagtact gacggaaaga gtggagtgca
    15721 aaccacgtgg agtcggaggt ttgtgggagc cgaccgtctg ggcagtattt gaaatattca
    15781 gatactggcc tttttttata actttcaggg cagaaatcag gaataccagg cagaccggcc
    15841 aatacttctt tcaattaata attgttgctg atcgcggagt gaacagcaac agaagttttt
    15901 catgttatgc ggaaacgaaa ggagaaaaac aattatggga ttcaaatcag acattgaaat
    15961 tgcacaggaa tgcgagatgc ttccaattac tcagatcgca gagaaagcag gtattgacga
    16021 caaatatctg gagcagtacg gaaaatacaa agcaaaaatc gactacaatc ttctgaaaga
    16081 aagtgataag aaggatggaa aattaatcct cgttacagct atcaacccaa ctccagcagg
    16141 agaaggtaaa actactacta ctgtaggtct tgcagatggt atgcagagac ttggcaagag
    16201 tgttatggta gctcttcgtg agccatcctt aggaccggta ttcggtgtaa aaggtggtgc
    16261 agcaggcggc ggatatgcac aggttgttcc tatggaagat attaaccttc acttcacagg
    16321 tgacttccat gccattggcg cagctaacaa cttactggca gctatgatcg ataaccatat
    16381 cttccagggc aatgcattaa acatcgaccc acgtaagatc acatggagaa gatgtgtaga
    16441 tatgaacgac cgtcagcttc gtaacgtagt agatggtctt ggcggaaaga caaacggtat
    16501 gcctcgtgaa gacggatacg acatcacagt tgcatctgaa atcatggcag ttctctgtct
    16561 tgcaagcgac atcaaagacc tgaaagaaag attatccaag atcatcatcg gatatacata
    16621 cggaaaagtt tccgagcaga aacctgtaac agcaggtgac cttcacgcag aaggcgctat
    16681 gacagccctg ttaaaagatg ctctgaaacc aaaccttgta cagactctgg aacacgttcc
    16741 tgcaatcgta catggcggac cattcgcaaa tatcgctcat ggatgtaact ctgtaacagc
    16801 tacaaagatg gctatgaagc ttgctgatta tgcaatcaca gaagctggtt tcggtgctga
    16861 ccttggtgct gagaaattcc ttgatatcaa atgccgtatg gctggtttaa aaccaagcgc
    16921 agttgtaatc gtagctacag tacgtgccct gaaatacaac ggcggcgttg ctaaagctga
    16981 ccttaacaat gaaaacctgg aagctcttga aaaaggtatc ccgaacctgt taaaacacgt
    17041 ttccaacatc aaaaacgtat acaaacttcc atgtgttgtt gctatcaacg cattccctac
    17101 agatacaaaa gcagagcttg actttgtaga agctaaatgt aaagaactgg gcgttaacgt
    17161 tgctctttct gaagtgtggg caaaaggcgg cgaaggcgga atcaaacttg cagaagaagt
    17221 tatccgtctt gttgaagaac caaacgactt ctcctatgca tatgaactgg aaggttctat
    17281 cgaagacaaa ctgaaccaga tcgttcagaa agtatatggc ggtaagaaag tagttctgac
    17341 agctaacgct cagaaacagg cgaaacagtt agaagctctt ggctttggca actgcccgat
    17401 ctgtgtagct aagacacagt acagcttaac agatgaccag actaaactgg gtgctcctac
    17461 tgactttgaa gttacagtac gtaacctgaa gatttccgct ggtgcaggat tcatcgtagc
    17521 tcttacaggc gagatcatga caatgccagg tcttcctaaa gttccggctg ctgagagaat
    17581 cgacgtagac gagacaggta agatcacagg tctgttctaa tccggttgaa atcaatcgaa
    17641 taattcaaaa atataaaaat catatttata tatgatatgt gtccagacga ttttacaggc
    17701 gggaagattt tcccgcctgt ttttttcttt atttttttat aagataatct tttccggaaa
    17761 taccaggttc cgtcatatgg atcggatcca gaatgcgatt aagttcatcc tcgtccataa
    17821 gcttttcttt cagaatcaga cttcttacag attcgcctgt cttaattgcc ttttttgcaa
    17881 tatccgcagc cttctgatat ccaagatggg ggctgattgc agtgataata cctacactgt
    17941 tttctaccag ataacggcat ctttcttcat ttgccgtaat tcctacaata caattatcca
    18001 ccaatgtctg gactgcatag ccaagagtat cgatagactg gaacatgcaa tagaaaataa
    18061 tcggctcaaa cgcatttaat tccagctgac cagcctctgc agccatggta atggtaacat
    18121 cattaccaat aatattaaaa gcaacctgat tcactacttc aggaataacc ggattaactt
    18181 tacctggcat aatagaggaa ccattctgtt ttgccggaag attaatctcc ccaaaaccag
    18241 tacgtggacc ggaggacatc agacggagat catttgacat tttggaaaga gttaccgcac
    18301 atgctttcac agcaccggaa acggctacaa atggatccag attctgagtg gaatcaatca
    18361 gatcaaaagc ctgtataaag tccattcccg atatttcagt gagatttgga acaattcttc
    18421 tcagatagcc ctcatctgca ttaattcctg ttccaatagc agtacctccc atattaagag
    18481 tccgcatttc atccattgct ttatccattc tgtggatatc acgcatgatt gctaccgaat
    18541 atgccttaaa ttcctgtccc agacgaatcg gcactgcatc ctgcatctgt gtacgcccca
    18601 tttttattat gtgatcaaac tctgtagctt tttcattaag agcatcatat aggcgaagaa
    18661 gctgtttttt cagattctgc aacaaacgaa gagaagtcat tttaccggca gtaggaataa
    18721 cgtcattggt agactgtcca caattcacat catcgttagg atttataatt gtataatcgc
    18781 ccttttttcc tcccagtatc tcaatcgcgc gatttgcaat tacttcattg gcattcatat
    18841 ttaaagatgt gccagctcct ccctgaacag gatccacaat aaattcatta tggaattttc
    18901 ctgaaacaat ttcatcacat gcctggacaa tcgcctgtgc ttttttcttc tcaagaagcc
    18961 ccacctcaca attggttatc gctgctgctt tttttatgta tgcaagactg ttaataattt
    19021 ccggatgcat attcagcccc gtaatgtgga aattttcagc cgcacgtaag gattgtactc
    19081 cataatatac atcttccgga atatccttta caccaataga atccctttct acacgatagt
    19141 ctgttttttt catagttatt cgccctccca tgtatttgcc ctcattatat atctctgcta
    19201 taatataatc aaatacatat atttttataa aatatatagt gtttaaatta tatatcggag
    19261 gagtttatat gtttcagggg atggaataca tctatgaggt ctacaaggaa aaaagctttt
    19321 ccaaagctgc tgctgctctt ttcatttcgc agccttcttt aagcgccaat gtaaaacgtg
    19381 tggaaaaccg tattggctat cctatttttg atcgaagtac caaacctttg cagttaactg
    19441 aagttggaaa acattatata caggctgttg aaaaagtcat ggatattgaa aataatctcg
    19501 aaaactacct actggatctg ggaaatctca aaacaggaac tcttaatgta ggtggcagta
    19561 actttttttc ttcgtggatt ctgcctcccc ttattgctga tttttcccaa aaattccccc
    19621 atgttcaaat ttctcttgta gaagaaagta cagcaaaact atcccagttt ctccaggccg
    19681 gaaagttaga tctggtgatt gataactgta ttctggataa ccagattttt gaacgttata
    19741 tctaccagaa agaacaactt cttcttgcag ttcccaaaaa ttattcagta aataccagac
    19801 tgcagaaata tcagattcct attgaggaaa tccggaacgg gcagttccgt tcttctcata
    19861 ttccttctgt tccattaaac aaattcgaga acgaaccatt tattattctt cgttcagata
    19921 atgataccgg taagcgtgca cttaccattt gtcaggaaaa tcacttttcg ccttctgtag
    19981 tatttcgcct ggatcagcag atgactgcct ataatattgc atgtttggga atgggtatca
    20041 ctttcatcgg ggatcttctg ctctccagag ttccaacaaa ttcagaactt gttttttata
    20101 agctgcccgg tcagagcagt aaacgcactg tgttttttta ctggaagaaa ggccgctata
    20161 tcagcagagc catggaagaa ttcctgaagc tgcccttttc ctgatatgtc ataatcaaat
    20221 aggctatggt gattggtcat catcagatgt acgtcaaaat ggggttgttg tgctaaataa
    20281 gcacaacaac cccagtatgt caggcagata ttcgattaga acaatggctt catcgccgga
    20341 tacagagttc tgaacttctg atatctctct tcatattttg caaccagttc aggatccggt
    20401 tctactgtat caacaacttt ggcaaatttc ttaccgatgg tttctacatc cgggtaagca
    20461 ccacagccta ctgctgccag catagctcca cccatggacg gtccttcttc gttctccaga
    20521 acatcaacct tcaggttcat aacgtttgca atgatcttct tccacagtgg gctcttagct
    20581 ccgccaccgc agatcttggt tctctcaatc ttgattccaa ggcctcttgc aacttccagg
    20641 gaatcacgaa gaccaaaggc aacaccttcc agaacagcct gtgtcatgtc tgctcttgtg
    20701 ctgtccatgg acatcccgaa gaatacacct cttgcatcag gattattatg aggtgaacgt
    20761 tctcccatca aatatggaag gaagaataca tgattctctc ccagcttctg aattggagcc
    20821 tgctctgctg cgaaatcctt tgtctgaaga atctcctctg cccaccattt gttacaggaa
    20881 gctgcgctga gcatgcatcc catcagatga tagcttccat ctgcatgaca gaaagaatga
    20941 agtgcgttat tttcgtccac accaaagttt ttactggaaa taaacacagt tccggatgtt
    21001 ccaagagaaa tattacactg accgtcacca actgtacctg ttcctacagc agctgccgca
    21061 ttgtcacctg cacctgcaac aacttttaca ttctcactga atccaagttc tttcgcaatc
    21121 tcaggtttca gagttcctac tacttcccaa ctctcataca gtttcggaag ctgctcttct
    21181 gtgattccac agatctccag catttctttt gaccagcagc ggttcttcac atcaagaaga
    21241 agcataccgg aagcatcaga aacatctgta caaaaagaac cggacagacg atatgccaga
    21301 taatccttag gaagcataat ctttactacc ttcttaaagt tctcaggctc atttttctgc
    21361 atccagagga tcttcggtgc tgtgaagcct gcgaaagcaa tatttgctgt atactgtgaa
    21421 agtttgtctt ttccgatcac tgtattcaga tattctgtct cttcgcctgt acgtccgtca
    21481 ttccagagga ttgcaggacg gatcacatta tcatccttgt caagtgttac cagaccatgc
    21541 atctggccgc caaaaccaat tcctgctacc tgcgctctgt cgatatcctt tgtcagctct
    21601 ttcatgcctt ccatactctg cgcaaaccag tcttccggtt tctgctcaga ccagcccgga
    21661 tgtgggaaga ataaaggata ttctctggat acgatgttac agatttttcc tgattcttcc
    21721 ataagaagaa gttttacagc ggaagtacca aggtcaatac caatataata cataagtgct
    21781 ctccttttct atttctaatc taatacatcc cagagcaaag ccccgggatg cctttaatat
    21841 agtgtcagtt tatttattct gtattcagat tcattcactt cacatgaaca ttaataatcc
    21901 gttttactga tttctcatta accccatgga ttttctgtcg ggtatcttac acctgccggc
    21961 tggttatatc caatcttctt aacatccagt ccaaggaatt tcactacctc atagaatgct
    22021 tttccgtaat gtccaaacat aactgctcca tgatgcggat agttgccctc gatcagtacg
    22081 tgacggtaga atcttcccat ttctttgatt gcgaaaatac cgataccacc gaatgatctt
    22141 gtaggtacat ccagtacttc accttctgca acataagaaa ccagctcgcc ctcggaattg
    22201 cactgtaaac gatagaatgt aatgtcagat gcagcgatat caccttcaag agttcctctt
    22261 gtgaagtctg gttcagatcc tgccggctca agaagtctgt gctggatcag ctgatattta
    22321 acagctctgg aatcacacat cttgcatgca ggagtatttc cacaatggaa tcccataaat
    22381 gtatcagtaa gcttataatc gtattttcct ttgatatctt catcatagat atactgtgga
    22441 acagagttgt tgatatcaag cagtgtaact gcatcattgg aaatgcaaag tccgatgtac
    22501 tcgctgagtg ctccgtagat atcaacctca caggataccg gaattcctct ggaaaccaga
    22561 cggctattta catagcaagg ttcaaatcca aactgtgacg ggaatgcagg ccaacatttg
    22621 tcagcaaatg caacgtattt tcttgctccc ttatgagcct ctgcccagtc aagaagtgta
    22681 agctcaaact gtgccatttt cacattaagg tcagcataat atttgccttc gcccatctct
    22741 tttgccatat ctgcacaaac ttccgggata cgaggatcat tttcatgctc tttgaaagaa
    22801 acaagaagat caagctctga gttctcttca atctcaacac ccagctcata gaggccttta
    22861 ataggtgcgt tgcatgcgaa gaagtcctgt ggacgtggtc cgaaagtaat gatcttaaga
    22921 ttgctgacac cgatgactgc acgtgcaacc ggtacgaaat cagcgatcat ctttgcaata
    22981 tcatctgctg ttccaacagg atattccgga atatatgctt tcagatgacg catttttaag
    23041 ttgtaggagc agttaagcat accacagtaa gcatcacctc tgccgttgat catatcaccg
    23101 tcaccttctg ctgctgctac atacatacaa ggtccgtcaa atctctctgc gatcagagtt
    23161 tcaggagttt caggtccgaa gtttccaagg aaaacaacca gcgcattaca ctctgctttg
    23221 tttacatctt caagagcttt ctccatatc
//
