LOCUS       c00076_gnlPro..        16880 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MOPEJPLJ_136.
ACCESSION   c00076_gnlPro..
VERSION     c00076_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:02:29
            Original ID  :: gnl|Prokka|MOPEJPLJ_136
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16880
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16880
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5523:7775]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5524..7775
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16880
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16880
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             3..410
                     /locus_tag="ctg76_1"
                     /transl_table=11
                     /translation="MQGKISGKKKQKLHLWRKRDIQKCCEHQAHRKGMRVSRICAWNTS
                     RLAYDGSGAVTRDWENHSLCTFQTGKRYNCDLSASYNIGARYFIRELLKPLPATERSLL
                     EAKVPPVKRRTSCVYADLRELHLQMEILKVA"
     CDS             1100..1537
                     /locus_tag="ctg76_2"
                     /transl_table=11
                     /translation="VATKVDKKNAIRQGITEAEIVYFQNLAGKTFLYVCGDEYFEVSFP
                     IDHFLHLTGVETRLSTKDFYKNAKKSILTNNQFYFDARHVYANAKRKLPCLKRLPELTN
                     EMVCVLKNMETMTITYKLSVTNLEFTGSVTRKPKRYTGKKD"
     CDS             1669..2028
                     /locus_tag="ctg76_3"
                     /transl_table=11
                     /translation="MPKTSYICNCDVIHEDIVNDVKSKMQPKDDYIQLASLFKLFGDGT
                     RVQILHALEQSEMCVCDLAVLLGVTKSAISHQLKALRLANLVKFRKEAQIVYYSLADDH
                     VKEIIDKGFEHLWQK"
     CDS             2088..4442
                     /locus_tag="ctg76_4"
                     /transl_table=11
                     /translation="MKRIFLLKGLDCPNCSAKIEKEVGELDGVQSSVVNLMKQTITVNV
                     TQTAADTIASQIETIVYSHEPDVEVQEETVMNVTKSYSLKGLDCPNCSAKIEKEVGELD
                     GVQSSVVNLMKQTLTINVAQTAADTIASQIETIVHSHEPDVEVSEIVQESYIPEKKQEA
                     NESYNNEDKKLTVRLATGAAIYAIGMALTVFAKVPLPIELAFLIVSYVILGGDVVWQAV
                     RNISKGRVFDEHFLMSVSTIGAFVIGEYPEAVAVMLFYQVGEFFQSLAVKRSRKSISDL
                     MDIRPDSATVRRNGELITISPENVSIGEIIIVKPGEKIPLDGVVLDGDSMLDTRALTGE
                     SVPRSVHKGDEALSGCMNQTGVLMIKTTKAFGESTASKIIDLVENASSRKAPTENFITT
                     FARYYTPVVVILAAFLAILPPIILGGGWTEWIRRGFVFLVVSCPCALVISIPLTFFGGI
                     GAASKRGVLVKGSNYLEALNNVSVIVFDKTGTLTKGVFNVTDILPANGFSKEQVLEYAA
                     EAESFSNHPIAKSILAAYGKEMDQSVIFDYKEISGYGISVMAGEKKVFAGNTKLMDTEC
                     IEYTTCEKAGTKVYLAVDGQYAGCILITDEVKPDSKKAISDLKHIGVEKTVMLTGDDEK
                     IGKSVAEELQLDEYYAQLLPDQKVEKVELLDSKKRPGSKLAFVGDGINDAPVLARADVG
                     IAMGGLGSDAAIEAADVVLMTDEPSKLVDAIEVAKATKQIVMQNIVIALGIKSVFLILG
                     ALGIAGMWEAVFGDVGVTIIAVLNAMRILKK"
     CDS             4459..4977
                     /locus_tag="ctg76_5"
                     /transl_table=11
                     /translation="VKRKLILLVVTIVFLVGFGVILHSPPSMIDAVTGATPKSKKAAQA
                     SAQLEGSYVLGINMMSDGLDNENTRNKLKELALDDSETNETDLMKTDISFRLYVSETDY
                     PLVSYAKKLCDRLKQAGFSVDLKEYSNTMMLSRVVSGKYDVFLASDDFIDVTTLTQMDY
                     MIMDSEEMR"
     CDS             4988..5527
                     /locus_tag="ctg76_6"
                     /transl_table=11
                     /translation="MRKWNTILSVLMLLIFMIHGIMGSFMLNGVGSSAGKLLAWIGVGI
                     LVVHTVIGVILTVQSLQTAKQSGKMYLKQNAIFWARRASGLAILILLFFHIGLFGKVQN
                     GTYILFPFTTVKMVTQLLFVAAIFVHIFINIRPLLVSLGIISYKERRGDIYLILSVLLL
                     FIAGAVIFYYIGWQYL"
     CDS             5524..7068
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 270.5; E-value:
                     9.3e-83)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_7"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.6e-83, bitscore:
                     270.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.7e-17,
                     bitscore: 52.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTIIIIGAGLAGLSAALQAAENGCNVKLVSSLPSERAQSVMAE
                     GGINAALNTKDENDSPEEHFTDTIKAACGLADPNAVWGMTQAAPELVHWLLKLGVKFNM
                     SGYDDVDLRNFGGQKKKRTAFAQSDTGKQIMTAMIDAVRRKEASGMVERFSHHSFLTLR
                     LCGNICCGCVIRDEYSQETVELPGDAVIVATGGMHGLFGNTTGSLSNTGEVTAELFRLG
                     VPLANSEMIQYHPTTVKCGGKRMLISEAARGEGGRLFAMKDGKQWYFMEEKYPELGNLM
                     PRDITAREIWKVSHESEVFLDMTEISEEIISNKLSGLADDCMTYLHKDIRKEPVSVLPG
                     IHYFMGGILVDEQHRTPIQNLYAAGECCAQYHGANRLGGNSLLGALYGGRVAAKSAREQ
                     ADVVDLSCATQIDFPPTSQISEIKQLNKVMQDTMGVVRNENTLLNGIQTVQALTGNLPL
                     LGMAVLKSALARKESRGAHWREDYPKSNDDDYLKTTVARFDGKQIQISFVPVPERR"
     CDS             7074..7775
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 91.5; E-value: 1.1e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_8"
                     /sec_met_domain="Fer2_3 (E-value: 3.1e-29, bitscore: 91.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00071, bitscore: 10.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVYKIRIRRQESQKSDSYWQEFEFDGSKNSSVANVLKELNSRTPL
                     KDNSGNIVTPISWECSCMVRKCGACAMLINERPRLACSTFLHTLKGSTITLEPLSKFPL
                     VRDLIVDRSILFENLKKLNLWLESEAYMNRWTHEPRYQSARCLMCGCCLEVCPNFSANG
                     TFAGAVAAVNAFRILNEEQESTHLNEISAEYKKKYFEGCGKSLSCHDICPIGLPVEELL
                     VRSNAAAVWGK"
     CDS             7800..8543
                     /locus_tag="ctg76_9"
                     /transl_table=11
                     /translation="MYEENQKLKTWITPDLATEYLAGAVLLGAAPCTAMVFVWSTLTKG
                     NPAYTVVQVASNDIIILFAFVPIVKFLLGVSNVSVPFQTLFMSVVLFVVIPLAAGIITR
                     LLVVRKKGTEYFEQTFLHKFDSATTVGLLLTLILIFMFQGEVVLDNPLHIILIAVPLII
                     QTFFIFFLAFGVCRIIRLPYDIAAPAGMIGASNFFELAVAVAVALFGTSSPAALATTVG
                     VLTEVPVMLTLVKIANKLKEKFKYE"
     CDS             8536..8949
                     /locus_tag="ctg76_10"
                     /transl_table=11
                     /translation="MNKKKVAFICVHNSCRSQIAEALGKHLASDVFESYSAGTETKLQI
                     NQDAVRIMKELYGIDMEAEGQYSKLIDEIPVPDIAISMGCNVGCPFIERPFDDNWGLED
                     PTGKSDEEFKKVIDEIRMQIFILKQRLDEFEEN"
     CDS             9259..9498
                     /locus_tag="ctg76_11"
                     /transl_table=11
                     /translation="MRTIYAEYNINHDSIDVYTSAGYMLRIDCWEAEKNLKTTYGSECA
                     LTSLAVDEPLEYARLYLDGNLQMWVDTEDSLELY"
     CDS             9748..10437
                     /locus_tag="ctg76_12"
                     /transl_table=11
                     /translation="MKHILIVEDDNLLNKTLTYNLELDGYTITSVLNARTAAESLKTNI
                     FDLVLLDINLPDGNGYDLCRLIKPEHPDTVVIFLTANDQESNQIRGYEAGAVDYITKPF
                     SISALQRKIKAMFAMLEHHKPAKDIYEDGSLFLDFSEQFASLNGKPLALSAMEYKMLNL
                     FLKNPKQVLTRQQFLEKLWDVDEKYVDEHTLTTSISRIRSKIEADGDTYIKTVYGMGYQ
                     WTGGEKK"
     CDS             10434..11465
                     /locus_tag="ctg76_13"
                     /transl_table=11
                     /translation="MNLNNLSAKKICRLVSAGMVFSMLVITGIFGGIMQDIRIFIVGGT
                     LTLCAFFWIWLLVLIFGKRLSHFTSNLCRTLDNMIDGNEELQKSNDSETLFARINHRLI
                     RLYEIMQKNRHKVDMERQELQMLISDISHQVKTPVSNLQMVTDTLLTKPVSEEERMDFL
                     QGIRSQTDKLDFLFQALVKTSRLETGAIRLEKKDSSLFHTLAQAMSSIVYVAEKKEIAV
                     SVDCPENLIISHDSKWTSEALFNLLDNAVKYTPSGGKISVSVVQWEMYVEVKVTDTGKG
                     ISESNQAAIFRRFYREEEVHDQQGVGIGLYLAREIVTRQGGYIKVVSELGQGSEFSIML
                     PVR"
     CDS             11617..12282
                     /locus_tag="ctg76_14"
                     /transl_table=11
                     /translation="MSILQTIDLKKYYGTEPNITRALNGVNFTVEQGEFVAVVGTSGSG
                     KSTLLHMMGGLDTPTSGSVIVRGEELAKKNDDELTIFRRRNIGFIFQNYNLVPILNVYE
                     NIVLPVELDGDTVDQKFMDEVVYMLALEDKLENMPNNLSGGQQQRVAIARALITKPAII
                     LADEPTGNLDSKTSADVLGLLKHTSGEFNQTIVMITHNNEIAQLADRIVRIEDGKIVG"
     CDS             12297..14624
                     /locus_tag="ctg76_15"
                     /transl_table=11
                     /translation="MNYPFENDTSAVIKKLARKSVRFDKKKNLFCLSAIIVAVAMIMMS
                     LLTVQNIIYQNQKEIEGLHQGIFFDITQDSKEKLLANEEVKSVGLSCNIKTVKENSKEL
                     SLIYYDDDMLSLIPAFDGKYPEKASEIAVTDAFFASENKSPEINAIVQLNLDGTLKNYT
                     IVGIYHDKTSTAYPVFVSLEKCRELRGNNLLNGYVWLENADTLTKDEATEILSQISEET
                     GLNNWTVSSYYDYVNTTLSFSNYAVYGVVAAILFLAAALVIYSIFYISVGQKVAEFGQL
                     RTIGASKKQIYKIVLKQGYMLAVPGILIGSIMGTIISYCLQSKGWSVFAFIVSLCGACL
                     FGILLVYISVRKPAKIAANTSPISALKNPVGIVNYRTHKRHRITPVYLAKISFSRNRKK
                     SLLTILSLGLCGVIFFLAASYQSSFNAESMARYWDMKYGDFKISIDLENESENLDALLQ
                     KEYFSDYVKRVGDIEGVSNIFTYATVPVDFSTDNDISDSTLMLGYNEKDLASLNAAVLS
                     GNITDDTELVVSDPERIYDVYHWKPQIGDTVTFNFKNHSGKTITKAFKIGAITSSNDGM
                     GGYIFRMPENMLKELAGYDCTYAIEIQAEAEYQEIIEQELKLLVSDNRDVRLQTLQDFI
                     VEHQSDNRAGFTLAYAIAAILWIFAVINQINLTVTNLLSQKQEMGTLKSIGMTNKQLKQ
                     AFMMEGLFTTLIALLITAVVGIPGGYAIGIFLKNAGMSTGFVFPVVAFTLFAVAMFMLE
                     SLMTILLIHSWKKQSVIAIMRN"
     CDS             complement(14820..15785)
                     /locus_tag="ctg76_16"
                     /transl_table=11
                     /translation="MNESRESKNAEQLEELLLLTEEIQEELEQKEQLIVELKTQLSESL
                     TLNEKLNKENRAGNIQALKNDLKLADRALRIEKEKLRSANVMIEECQDKICYLTQERDY
                     ARTHQKIVEIPVEKPVLYEKCEACNRTAYQNAKAKYETQKERLAGQYKAKTVMFQTTLF
                     LLAWYSLTTTLFQAVQSDMFLVDCKSFFNDLASFIQIFVGWTIDAGHSAAQISTKIPNA
                     FIAGMVYWLLLILIVGICMAGTGMLAILIEIKVIELYKKNCWDVITLLMILTSVAIVIY
                     FGESIKKVLSVNLLLLFVLSQGAYVGIRCYLKVWLEKRPY"
     CDS             complement(15804..16163)
                     /locus_tag="ctg76_17"
                     /transl_table=11
                     /translation="MTLEESREIIPLMESMIGQIEEQQNLMAEMILEMQNRDTQLSLMQ
                     KQNQKLQKLNNELSELLNILPNTEELLSKMEEQKTKIELLENENQQWQKLAQKLNSENS
                     LLLKQNTELLNWNSR"
ORIGIN
        1 agatgcaggg gaagatatcg ggaaagaaaa aacagaaact gcacctgtgg agaaaaagag
       61 atatccagaa gtgttgtgaa catcaggcac acaggaaagg gatgcgggta tccaggatct
      121 gcgcatggaa taccagcaga ctggcttatg atggttccgg ggcggtaaca cgtgactggg
      181 aaaatcacag cctctgtact ttccagacag gaaaacgata taattgtgac ctgtcagcat
      241 cctataatat aggggcgaga tattttataa gggaactttt aaaacccctt ccggcaacgg
      301 aaaggtcttt actggaggca aaagtccctc ctgtaaagcg tagaacctca tgtgtttatg
      361 ctgacttaag agaacttcat ctgcaaatgg agatcttaaa agtagcataa acacaggcag
      421 atatacagcg gattacctgt aatgtgggaa cctgccgtat ccggcatgga aaaagcacat
      481 aactgtgcag acctaagtta caggcgtatc cgccgatatt cagtctgacg cctaaagcgt
      541 ctggaagcac gtgactttag ccatgtgagg ttcacgatta tcggaaaatg cctgtaaaca
      601 gcgtaaatac agcatttcaa ggagttttaa gcaatgataa gagtgttatt tgtctgccac
      661 ggcaatgttt aatggatgcc gtgaaagcct tgattttatt ggatttcttg ggaattaacc
      721 aataatttac accttattta tacctttgga agaccggatc ggaataatat aataaaattt
      781 gctaatctgt gttgattttt tttatgattg agtataataa aatcaagaac agaaatgttc
      841 tcgatgtaag agcatcgtta aaagttgggc tgcagatgga gcagggtaaa cttccatctc
      901 attagatgtc ttaactgggc atcgagcctg gtagcttgga taaagctgta gtccacgtgg
      961 gggacttaat gattttcacg tcgttatggg tatcttaact gggtatcgag gctgacaacc
     1021 agcagaaaac tcttttacaa aagtaattct cagaaaagtg tggtttaatg ccacactctt
     1081 ttttgcatgt gaggtataag tggcaacaaa ggtagataag aaaaacgcaa tacgacaagg
     1141 tattacagag gcggaaatcg tatatttcca aaatttggca ggtaaaacat ttctgtatgt
     1201 ttgtggagat gaatattttg aagtttcttt tccaatagat cactttctac atttaacagg
     1261 agtggagaca agactttcga ccaaggattt ttataagaat gcaaaaaaat ctattcttac
     1321 aaataatcag ttctattttg acgcaagaca tgtatatgca aatgccaaaa ggaaacttcc
     1381 gtgtttaaaa cgcttgccgg aattaacgaa tgaaatggta tgtgttctaa aaaatatgga
     1441 aaccatgaca attacatata aactcagcgt tacaaatttg gaatttacag gaagtgtgac
     1501 aagaaagcca aaacggtata ctgggaaaaa agattaagaa aagaataaag agctggtttt
     1561 aattgtaaaa tttatgggga actaacatca gcttattgac atgaatttaa aaataagtat
     1621 aataatagtt gagtaattgt tcaactatta ttatttggag gtgaatatat gccaaaaacg
     1681 tcttatattt gtaattgcga tgtaattcat gaggatattg tgaatgatgt gaaatccaag
     1741 atgcagccaa aagatgatta tatccagttg gcttctttgt ttaagctatt tggagatgga
     1801 actagagtac aaatcttaca cgctctagaa cagagtgaga tgtgtgtatg tgatcttgca
     1861 gtgctactgg gggtaacaaa atctgcaatt tcgcatcagt taaaggcatt acgccttgcg
     1921 aatctggtaa aattccgtaa agaagcacag atagtttact actcactggc agatgatcat
     1981 gtgaaagaga ttattgacaa gggatttgag catctttggc agaaataata ttttttaaca
     2041 ttatagttga gtaattgaac aattaaacaa attataagga gattatcatg aaacgcatat
     2101 ttctattaaa agggttggac tgtccaaatt gttccgcaaa aattgaaaaa gaagtcggag
     2161 agttggatgg agtgcaatcc tcagtggtaa atctgatgaa gcagacgatt acagtcaatg
     2221 ttactcagac agccgcagat acgatagcca gtcagattga aacgattgtt tatagtcatg
     2281 agccagatgt ggaagttcag gaagaaaccg ttatgaatgt tacaaagagt tattcgttaa
     2341 aagggttgga ctgtccgaat tgttccgcaa aaattgaaaa agaagtcgga gagttggatg
     2401 gagtgcaatc ctcagtggta aatctgatga agcagacgct tacaatcaat gttgctcaga
     2461 cagccgcaga tacgatagcc agtcagattg aaacgattgt tcatagccat gagccagatg
     2521 tggaagtttc tgaaattgta caggaatctt atataccgga aaaaaagcag gaggccaatg
     2581 aatcctataa caatgaggat aagaagttga cagttcgttt agcgactggt gcagcaatct
     2641 atgccattgg tatggcattg actgtttttg cgaaagtgcc actgcctatc gagttagctt
     2701 ttctcattgt ttcttatgtt attcttggtg gagatgttgt atggcaggct gtgaggaaca
     2761 tttcaaaggg gcgtgtattt gatgaacatt ttttgatgag tgtttctacg attggggctt
     2821 ttgtcattgg tgaatatcca gaagcagttg ctgttatgtt attctatcag gtaggtgaat
     2881 tttttcagtc attggctgtt aagcgttcca gaaaatctat atcagactta atggatatac
     2941 gtccagattc tgctacagta agaagaaatg gggaattgat taccatatct ccagaaaatg
     3001 tctccattgg tgagattatt attgtaaagc ctggtgaaaa aattccatta gacggtgtgg
     3061 tattggatgg agattctatg ctggatacaa gggccttaac aggagaatca gttccgagaa
     3121 gtgttcataa aggagacgaa gcactttccg gttgtatgaa tcagacgggt gtcttaatga
     3181 ttaagacaac aaaagcattt ggtgaatcta cggcttcaaa gattattgat cttgtggaaa
     3241 atgcgtcaag ccgaaaagca ccaacagaaa attttattac tacatttgca cgttattata
     3301 cacctgtggt tgtaatctta gcagcttttc tggcgattct gccaccgatc attcttggcg
     3361 gaggctggac agagtggatt cgcagaggat ttgttttcct tgtggtatct tgtccatgtg
     3421 cattggttat ttcaatcccg ctgactttct tcggcggcat tggtgcagca tctaaacgag
     3481 gtgttcttgt aaaaggaagc aattatttag aggcacttaa taatgtcagc gttattgtgt
     3541 tcgataaaac cggaacactt acaaaaggtg ttttcaatgt gacggatatt ttgcctgcaa
     3601 atggattttc aaaagaacag gttctggagt atgcggcaga ggcagagagt ttttctaacc
     3661 atcctattgc aaaatccatt cttgctgctt atggaaaaga aatggatcag tcagtgattt
     3721 ttgattataa ggaaatttca ggatatggaa tcagtgtaat ggcaggggaa aagaaagttt
     3781 ttgctggcaa tacgaaactt atggatacag aatgtataga gtacacaacc tgtgaaaaag
     3841 caggtacaaa agtttatttg gctgtagatg gtcaatatgc aggatgtatt ttgataacag
     3901 atgaagtgaa gccggacagt aaaaaagcaa tttctgacct gaaacatatc ggcgtggaaa
     3961 aaacagtcat gcttaccggt gatgatgaaa aaattgggaa gtctgttgca gaagaattgc
     4021 agttggatga atattatgca cagctgcttc ctgaccaaaa agtggaaaag gttgagcttt
     4081 tagatagtaa aaagagaccg ggaagcaaat tggcttttgt tggtgatggt atcaatgacg
     4141 ctcctgtcct tgcccgtgca gatgttggta ttgcaatggg tgggcttggt tcggatgcgg
     4201 ccattgaagc agcagatgta gttctgatga cagatgaacc gtctaagctg gtggacgcga
     4261 ttgaagtagc aaaagcgaca aaacagattg tcatgcagaa tatagtgatt gctcttggga
     4321 ttaagagtgt gttcctgatt cttggcgctc ttggtattgc gggaatgtgg gaagctgtat
     4381 ttggtgatgt aggcgttacc ataattgctg ttttgaacgc aatgagaatt ttgaaaaaat
     4441 aggaaatgag gtggaaatgt gaaacgaaaa ctgattctgt tagttgttac gattgttttt
     4501 cttgtaggtt ttggtgtcat tttacattca ccgccttcta tgattgatgc agtcacagga
     4561 gcaacaccga agtcaaaaaa ggcggctcaa gcctccgcac agttggaagg ctcttatgtt
     4621 ctcggtatta atatgatgtc agatggtctc gacaacgaga acacccggaa taaattaaaa
     4681 gaattggcac tggacgattc ggaaacaaat gaaacagatc tcatgaaaac ggacattagt
     4741 tttcggttat atgtatctga gacggattat ccgcttgtca gttatgctaa gaaactctgt
     4801 gacaggttga aacaggccgg tttttccgta gatctgaaag agtacagtaa cacaatgatg
     4861 ctatcaagag tggtaagtgg aaagtatgat gtattcctgg catcggatga ttttattgac
     4921 gttacaacgc taacacagat ggactatatg atcatggaca gcgaagaaat gaggtgagcg
     4981 ggaatttatg agaaaatgga atacgatttt gtctgtttta atgcttctca tttttatgat
     5041 tcatggaatc atgggaagct ttatgctgaa cggagttgga agtagtgcag ggaaacttct
     5101 tgcatggatt ggtgttggta ttcttgttgt gcatacggtg attggtgtca tcctgacagt
     5161 tcagagttta cagacagcga agcaatccgg aaaaatgtat ctgaaacaga acgccatatt
     5221 ctgggcgaga cgagccagtg ggctggcaat actgatcctg ctgttcttcc atattggctt
     5281 gtttggaaag gtgcagaatg ggacatatat tttgttccct tttacaacgg taaagatggt
     5341 aactcagctt ttgttcgtgg cggcaatctt tgttcatatt tttatcaata tccgcccatt
     5401 gctcgtatcg ctgggaatca tcagttataa agaacgaagg ggtgatattt atttgattct
     5461 ttcggtgctc cttctgttta tagcgggcgc agttattttc tattatattg ggtggcaata
     5521 tctatgagta agacaattat tattataggt gctggactgg caggactttc agcggctttg
     5581 caggcagcgg aaaatggatg caatgtaaaa ctggtttcct cccttccgtc agagcgggca
     5641 cagtctgtta tggcggaggg cggtatcaac gcagctttga atacaaaaga tgaaaacgac
     5701 agtcccgaag aacattttac agatacaata aaggcagcat gtggtctggc agatccaaat
     5761 gcagtttggg gaatgacaca ggcagcaccg gagctggtgc actggctgct aaaacttgga
     5821 gttaaattta acatgagtgg ctatgatgat gtggatctgc ggaattttgg cgggcagaaa
     5881 aagaaacgga ctgcttttgc acagagcgat accgggaagc agatcatgac agctatgata
     5941 gacgctgttc gcaggaaaga agcatctggt atggtagaac ggttcagcca tcattctttc
     6001 ctaacacttc gtctgtgtgg caatatttgt tgtggctgcg taatcaggga tgaatacagt
     6061 caggagactg tggaattacc gggggatgcg gttattgttg ccaccggtgg tatgcacgga
     6121 ttgtttggaa atacaacggg ttcgctgagc aatacaggag aagtcaccgc agaattgttc
     6181 cggcttggtg ttcctctggc aaatagcgag atgatccagt accatccgac aactgtgaaa
     6241 tgtggtggaa aacgcatgct catcagcgag gcggccagag gggaaggtgg caggttgttt
     6301 gccatgaaag atggaaaaca atggtatttc atggaggaaa aatacccgga gcttggaaat
     6361 ctgatgccac gagatattac cgccagagag atatggaagg tcagccatga atcagaggta
     6421 tttcttgaca tgacggaaat atcggaggag attatttcaa ataagctatc tggtctggca
     6481 gacgattgta tgacctatct gcataaagat atacgaaagg aaccggtgtc tgttttaccg
     6541 ggaattcact attttatggg aggcattctg gtggatgagc agcacagaac gccgattcag
     6601 aatctttacg ctgccggaga atgctgtgcc caatatcatg gtgccaaccg tcttggtgga
     6661 aattctctgt taggagcgtt atacggagga cgtgttgcgg caaaatcagc acgtgaacag
     6721 gcagatgtag tagatctatc ttgtgcgaca cagatagatt ttccaccaac gtctcaaatt
     6781 tcagaaataa agcaattaaa caaagtgatg caggatacta tgggcgttgt cagaaatgag
     6841 aatacgttgt taaatgggat tcaaacggta caagcgctga caggaaatct tccattgctt
     6901 ggcatggcag ttctaaagag tgctcttgca agaaaagaaa gccgtggtgc acactggcgg
     6961 gaggattatc cgaagagcaa tgacgatgat taccttaaaa caacggtagc cagatttgat
     7021 ggaaagcaga tacagatttc ctttgtacct gttccagaaa ggcggtgatt cacttggtat
     7081 ataaaataag aatcaggcgg caggagagtc agaaatcaga cagttattgg caggaatttg
     7141 agtttgacgg aagcaaaaac agctctgttg ccaatgttct aaaggaattg aacagtagaa
     7201 cccctttgaa agataattca gggaatatag ttactcccat cagctgggaa tgtagctgta
     7261 tggtgcgaaa atgtggggct tgcgccatgc tgattaacga acgtccgagg ctggcatgct
     7321 ctacatttct acatacgtta aaaggttcta caatcacctt ggaaccttta agcaaatttc
     7381 cgcttgtaag agatttgatc gttgaccggt caattctgtt tgaaaatttg aaaaaactga
     7441 acctttggct tgaaagtgaa gcttatatga atcggtggac acatgaaccg agataccagt
     7501 cggcacgctg tctaatgtgt ggctgctgcc ttgaagtgtg tcctaacttc tctgcaaatg
     7561 ggactttcgc aggcgctgtt gctgcagtca acgcatttcg gattctgaat gaagaacagg
     7621 aaagcactca tttgaatgag atttctgctg aatataagaa gaaatatttt gagggatgcg
     7681 ggaagtcgtt atcttgtcat gatatttgtc cgattggtct gcctgtggaa gaactgcttg
     7741 taaggtcgaa tgcagcggct gtttggggca aataaaatgg atgataaaag ctataatgaa
     7801 tgtatgaaga gaatcaaaaa cttaagacat ggatcacacc ggatcttgcg acggagtatc
     7861 tcgcaggagc cgtgcttctc ggagcagctc catgtaccgc tatggtattt gtctggagta
     7921 cgctgacaaa gggaaatccg gcttatacag tagttcaggt ggcatcaaat gacattatta
     7981 tattatttgc atttgtaccg attgtgaaat ttctgcttgg tgtttctaat gttagtgttc
     8041 cgtttcagac gttatttatg agtgtggttc tatttgtagt aataccactt gcagccggaa
     8101 tcataacaag gctgctggta gtcagaaaga aaggtacgga atactttgag cagacttttc
     8161 tgcataaatt tgattccgca acaacagtgg gacttttgct cacgctgata ctgattttta
     8221 tgtttcaggg cgaggtggtg ctggacaatc cactgcacat tatattgatt gcagttccgc
     8281 tgatcattca gacattcttt atattctttc tggcatttgg agtatgcaga attatcagac
     8341 ttccgtatga tattgcagcc ccggctggaa tgattggtgc atcgaatttc tttgagttag
     8401 ctgttgcagt cgctgtagct ttatttggta catcaagtcc agcggcactg gcaactacag
     8461 taggtgtatt aacagaagtc ccggtaatgc ttactcttgt gaagattgca aacaaattaa
     8521 aggagaagtt caagtatgaa taagaaaaaa gttgctttta tatgcgttca taattcatgc
     8581 agaagccaga ttgcagaagc tttgggaaaa catctggctt cggatgtatt tgaaagttat
     8641 tcggcaggga cagaaacgaa actacagatt aatcaggatg cagtccggat tatgaaagaa
     8701 ttgtatggaa ttgatatgga agcagaagga caatatagta agctgattga tgagatacca
     8761 gtaccggata ttgcaatttc aatgggttgt aatgtgggat gtccgtttat cgaaagaccg
     8821 tttgatgata attggggact tgaagatcca accggaaaga gtgacgaaga gtttaagaag
     8881 gttattgatg agataaggat gcaaattttt atattgaaac aacgattgga tgaatttgaa
     8941 gaaaactaaa gaagttgaga aattgcagtt gatatttcac atattttagg aaatttaata
     9001 actgttatat ttgattatca aattcttcgc aaacccttga aaatactaag tttgtagcaa
     9061 gtgaactttc ccttactctt tcccttgtgt tacattttcc cattgctttt catgaacctt
     9121 aatatgggaa aaattaaggg aaagaaaatt tcataacaca atataacata taacaataac
     9181 gacatggtga actgattgaa atgttttcga tatttaactc tgtaactgat tatcaaaaga
     9241 aaatggagat aagatacgat gagaacaatt tatgcagaat ataatataaa ccacgatagt
     9301 attgatgttt acacaagtgc tggatatatg cttcgcattg attgctggga agctgaaaaa
     9361 aatttaaaaa ccacatatgg atcagaatgt gcgcttactt cattggctgt ggatgagcct
     9421 ttggaatatg caagattata tcttgatggc aatttacaga tgtgggtgga tacagaagat
     9481 tcattagaac tttattaagc aagaagtgag atagtgttgt agggagtttc ctgtagttaa
     9541 agataccaca cccgatatga tgaacccacg cttatacact accagctatg ataaaagaaa
     9601 ggacagcaat ttgacactgc tgtcctttct tttataaaat tgcagtacac agaaaaaagc
     9661 tgtaaaatga aaaatatatt tgtccttgta acaattctcg gacatttgcc tgttatacta
     9721 tctgcaaaaa gaaaaggaag tgataatatg aagcatattt taattgtcga agatgataat
     9781 cttttgaata aaacgcttac ttataatttg gaattggacg gttacacaat aacttctgtt
     9841 ctgaatgcaa ggacagccgc tgaatcatta aaaacaaaca tttttgattt ggtattgctg
     9901 gatataaatt taccagacgg aaatggttat gacctatgcc gtcttatcaa gccagagcat
     9961 cctgatacag tagttatatt tctaactgcc aacgatcagg aaagcaatca gatacgggga
    10021 tatgaagctg gtgcagtgga ttatatcacg aaaccttttt cgattagtgc tttgcagcga
    10081 aaaatcaaag ccatgttcgc tatgttggag catcacaaac cagctaagga tatttacgag
    10141 gatggtagct tgtttctgga tttttcggaa caatttgcaa gtttgaacgg gaaaccatta
    10201 gcactttctg cgatggaata taaaatgttg aacctatttc ttaaaaatcc gaagcaggta
    10261 cttactcgcc aacaattttt agaaaaactg tgggatgttg atgaaaaata tgtagatgaa
    10321 cataccctta ctacttctat cagccgtatt cgcagtaaga ttgaagcgga tggcgacaca
    10381 tatatcaaaa cggtttatgg tatggggtat caatggacag gaggcgaaaa gaaatgaatc
    10441 tgaataacct ttctgctaag aaaatttgta gactggttag tgctggcatg gttttctcta
    10501 tgctggtaat taccggtatt ttcggcggta taatgcagga tatacgaatt tttatagtgg
    10561 gtggaacatt gacactctgt gcgtttttct ggatttggct attggtgctg atttttggaa
    10621 aacgcctttc tcattttact tctaatttgt gccggacgct ggacaacatg attgatggaa
    10681 acgaggaatt acaaaagtca aatgatagtg aaactctttt tgcccgtatc aaccaccgct
    10741 taattcggtt gtatgagatt atgcagaaaa accggcacaa ggtagacatg gaacgacagg
    10801 agcttcaaat gctgatttct gatatttcac atcaagttaa aacgcctgtc agcaatttgc
    10861 aaatggtaac ggacacactt ttaacaaagc ctgtttcaga agaagaacgg atggactttt
    10921 tacaaggcat acgtagtcag actgataaac tggattttct gttccaagca ctggttaaaa
    10981 cgtcccggtt ggaaaccgga gcaatacgat tagaaaagaa agacagcagc ttattccata
    11041 cgcttgcaca agccatgagc agtattgtat atgtcgcaga gaaaaaagaa attgctgtat
    11101 ccgtggattg cccggaaaat ttgataatct cccatgacag caagtggaca agcgaagccc
    11161 ttttcaatct gctggacaat gcagtaaaat acactccgtc aggtggaaag atttctgtat
    11221 cagtggttca gtgggaaatg tacgtagagg tcaaagtgac cgacaccggc aagggcattt
    11281 cagaaagcaa tcaggctgcc atcttccggc gcttctatcg tgaggaagaa gtacacgatc
    11341 aacagggtgt aggaataggt ttgtatttgg ctcgtgagat tgtaacaagg caagggggct
    11401 atatcaaggt cgtttcagag ctggggcaag gctcagaatt ttctattatg cttcctgtaa
    11461 ggtaagatat aaccactttt tttgaaatgt ccgagcgttg taacatttca ccctgatttt
    11521 cgataaaaat tttttctatc tcggacattt gtgtaacatt tgtggtttac aatggcttta
    11581 tcaacagata gaaagccttg aaaggagcat ttgaatatga gcattttaca aacaatcgac
    11641 ttaaagaagt attacggcac agaaccaaat attactcgtg cccttaatgg tgtaaatttt
    11701 actgtggaac agggagaatt tgttgccgta gttggaactt ccggcagcgg taagtctaca
    11761 ttgcttcaca tgatgggagg acttgatacc cccacttccg gcagcgtgat tgtacgggga
    11821 gaagaactcg caaaaaagaa tgatgatgaa ttgacaattt tccgccgtcg taacatcgga
    11881 tttatcttcc aaaattataa tctggttccg attttgaatg tatatgaaaa tatcgtcctg
    11941 cctgtggaac tggatggcga tacagtagac cagaaattta tggacgaagt tgtgtatatg
    12001 ttggctttag aagataaact ggaaaatatg ccgaacaatc tttcaggcgg tcaacagcaa
    12061 cgtgtagcga ttgcacgagc tttaattacg aagcctgcga ttatccttgc tgatgaaccg
    12121 accggaaatc ttgatagcaa gaccagtgca gatgtgttag ggcttttgaa gcataccagc
    12181 ggagaattta atcagaccat tgtaatgatt actcacaaca acgagatcgc tcaactcgca
    12241 gaccgcattg tacggattga agatggtaaa attgttggct aaaggaggtg ggaattatga
    12301 attatccttt tgaaaatgat accagtgcag taattaaaaa attagcacga aaaagtgtgc
    12361 gttttgataa gaagaaaaac ttattttgcc tttcggcaat tattgtagcc gttgctatga
    12421 taatgatgtc gttgctcaca gtgcaaaata tcatttatca aaatcagaaa gaaatcgaag
    12481 gattacatca agggattttc tttgacatta cgcaggacag taaagaaaag ttgttagcaa
    12541 acgaagaagt aaaaagtgta ggactttcct gtaatatcaa aacagtgaaa gaaaattcta
    12601 aagaactgtc tctgatttat tatgatgatg acatgcttag tttgattcct gcctttgacg
    12661 gaaaatatcc agagaaagca agtgaaattg ctgttacaga tgcctttttt gccagtgaaa
    12721 ataagtctcc ggaaatcaac gccatagttc agttgaatct ggatggtact ttgaagaatt
    12781 atactattgt tggtatttat catgataaaa cttctaccgc ttatcctgtt tttgtttcac
    12841 ttgaaaaatg ccgggaatta cgtggaaata acctgcttaa tggatatgtt tggcttgaaa
    12901 atgcagatac ccttacaaaa gacgaagcaa cagaaatatt atctcaaatt tcagaggaga
    12961 ctggactgaa taattggaca gtcagcagtt actatgatta tgtaaataca actttgtcct
    13021 tcagtaatta tgcggtatat ggtgtagttg ctgccatttt gtttttagct gccgcacttg
    13081 taatttacag cattttctat atttcggttg gacaaaaagt tgctgagttc ggacagcttc
    13141 ggacaatagg ggcaagtaaa aagcaaattt ataaaatagt tcttaaacag ggttatatgc
    13201 ttgcagttcc ggggatttta attggtagta tcatgggaac gatcatcagc tattgtctgc
    13261 aatcaaaagg ctggtcagta tttgcattta ttgtttctct atgtggcgca tgcctttttg
    13321 gaatactgct tgtttatatt agtgttcgta aaccagcaaa aattgcagcg aatacttctc
    13381 caatttccgc cctgaaaaat ccagtgggaa ttgtaaatta ccgcactcac aaaagacatc
    13441 gtattacgcc tgtatattta gcgaaaatca gcttttccag aaacagaaaa aaatctctat
    13501 tgaccatttt atcattggga ctgtgcggag ttatattttt ccttgcagca agttatcaga
    13561 gttcttttaa tgccgagagt atggctcgtt attgggatat gaagtacgga gatttcaaaa
    13621 tcagcattga tttagaaaac gaaagtgaaa atttggatgc tctcttgcag aaagaatatt
    13681 tttctgatta tgtaaagcgt gttggagata tagagggagt tagcaatata tttacttatg
    13741 ctaccgtacc agttgatttc tcaacagaca atgatatttc agatagcacc ttgatgctcg
    13801 gctataatga aaaggatttg gcgtcgctaa atgcagcggt tttgtctgga aatattactg
    13861 atgatacaga attagttgta agtgatcccg aacgtattta tgatgtttac cattggaaac
    13921 ctcaaattgg ggatactgtg acctttaatt tcaaaaatca tagtggtaaa acaataacaa
    13981 aagcattcaa aattggtgca atcacttcca gcaatgatgg aatgggtggc tatattttca
    14041 gaatgccgga aaatatgctc aaagaacttg caggttatga ctgtacatac gcaatcgaaa
    14101 tacaagcaga agctgaatat caggagataa tcgagcaaga actcaaatta ctcgtttctg
    14161 acaataggga tgttcgctta caaacccttc aagattttat tgtagaacac caatcagaca
    14221 atcgtgcagg ttttacatta gcttatgcga ttgcagccat cttgtggata tttgcggtca
    14281 tcaatcaaat caatcttact gtgacaaatc ttttatcaca gaaacaggaa atgggcacac
    14341 taaaatctat tggtatgaca aataagcagt tgaagcaagc atttatgatg gaaggtcttt
    14401 ttactacttt gattgcattg cttataactg ctgttgttgg aatccccggc ggatatgcaa
    14461 tcggtatatt tttgaaaaat gcaggcatgt ctacgggatt tgtatttccg gttgttgctt
    14521 ttactctttt tgctgttgct atgtttatgc ttgaaagttt gatgacaata ttgcttattc
    14581 attcatggaa gaagcaatct gttattgcaa taatgcgaaa ttgatgatag aaagcttttc
    14641 atatctcggt cagctccaca attacattac tctgctgata cagccagtcc gtaaattctt
    14701 tcgggctggc tgttcctgtt tttacagcct tttttctctg taatacttct tttcatacag
    14761 taaattttca ctaggctggt atggagtaat tttactgtct atacagtaag ttgaaaatac
    14821 taatatggtc ttttttctaa ccaaacttta agataacatc taattccaac atatgcgccc
    14881 tgcgaaagta cgaaaagcaa tagaagattt actgacagta cttttttgat tgattctcca
    14941 aaataaatga caatagcaac acttgtcagt atcattagta gagtaataac atcccaacag
    15001 tttttcttat ataattctat aacctttatt tctatcagta tcgccagcat ccctgttcct
    15061 gccatacata ttcctacaat caatattagc aataaccaat ataccattcc ggctataaaa
    15121 gcatttggaa tttttgtact aatctgtgcc gcagaatgcc cggcatcaat cgtccatccg
    15181 acaaagattt gtatgaatga tgctaaatca ttgaagaatg atttacaatc gacaaggaac
    15241 atatctgact gtactgcctg aaaaagagtg gttgtcaacg aataccatgc aagaaggaac
    15301 aaggttgttt ggaacattac cgtttttgct ttatactgtc ctgcaagtcg ctctttttgt
    15361 gtttcgtatt ttgcttttgc attctgatag gctgtccggt tacaggcttc acatttttca
    15421 tagagtaccg gcttttctac cggtatttct acgattttct gatgtgtccg ggcataatcc
    15481 cgttcctgtg ttaaatagca tattttatct tgacattcct ctatcatgac gtttgcgctt
    15541 cgcaacttct ctttctcgat ccgcaatgct ctgtctgcca gcttcaagtc gttctttaat
    15601 gcttgaatat tcccggctct gttctctttg tttaatttct cgttcaaggt cagagattcg
    15661 ctgagctgcg tcttcagttc cacgataagc tgttctttct gttctagttc ttcttgtatc
    15721 tcctcggtca agagcagaag ttcttccaac tgttcggcgt tctttgattc tctggattcg
    15781 ttcatctata tcacgtcctt tctctatctg ctgttccagt tcagcaattc ggtgttctgt
    15841 ttcagtaata aactgttttc gctgttcagc ttctgtgcca atttctgcca ttgctgattt
    15901 tcgttttcca aaagctctat cttcgttttc tgttcttcca tcttggaaag cagttcctcg
    15961 gtatttggca aaatgttgag cagctcggat aactcgttgt ttaatttttg taatttctga
    16021 ttctgttttt gcataagaga gagttgagtg tcccggttct gcatttccag aatcatttct
    16081 gccattaggt tctgctgttc ttcgatttga ccaatcatgg attccattaa gggtataatt
    16141 tcccggcttt cttctaatgt catttaatcg ctccttccat aatgataatg cacccgatac
    16201 tttcccaaag gtgtttagta tcttttgcaa taacgtgttt tgttgtttta tgatttgatt
    16261 ttccgctact ttccacgagc cttttatttc ctgcccggca aaaaactttt gttcaatctt
    16321 tcttgcgtca gctccttcat ggatggtagg aatctggagt tttccctgct tttcataaga
    16381 acgatgatca acttgattat gcaaaggcag atgttcatta catacctttg cccattcact
    16441 ccgccacagt tcacaatttt ttggattgtt ccatccagta gcatcggtca gcacccgttt
    16501 ccattgcagg cggtttcttg ctccaatctt ctgaattccg ttttcgtcta atacagggat
    16561 acggattcca tgacggtcag ggtttttctt atcctgccac cagttcggat gggattcatc
    16621 aatcacgata tttccgtttt tatctctgac aaaatcccaa tccttgactt ctttctttcc
    16681 ccaagaatga tccgggttaa aaggacgcat agttagaagc agatggacat gggggttgcc
    16741 atcccctttg tcgtggatac tccaatcagc gcacattcct ctatctacaa aagttttttg
    16801 gatatagtcg gttgtatatt gaatttgttc ctgtctgctc cattctttgg ggagggcaaa
    16861 ttcaaatgac ctgccaagtt
//
