LOCUS       gnlProkkaINIKEBBA_1    12142 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|INIKEBBA_1.
ACCESSION   gnlProkkaINIKEBBA_1
VERSION     gnlProkkaINIKEBBA_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 10:27:00
            Original ID  :: gnl|Prokka|INIKEBBA_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 3537110
            Orig. end    :: 3549252
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12142
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7142]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7142
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..12142
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12142
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="12"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(1428..2870)
                     /locus_tag="ctg1_3387"
                     /transl_table=11
                     /translation="MEKHQMKQLYQDIDVPKAELKNVIHSAAVRAGKEGAVRRRWGRKL
                     INGLAVAAALFILYLSSGLFMPSVNTAMGNIPVAGQIYSLFQDKAGSALFKSNLVTKLN
                     EKAESRGITVTVKSVYYDSGQLVYNFTVDNLKSDEESISFQVDYKDPWNMLAEDYDNSD
                     MKKMKDGQYAGQLRLFTDGSKLKDGDKLPLVITQIKDIPGNWRFTLPIKKQKSVSLEGT
                     KAVNVNHGLYRFFDIRAENGTTGSALLYSIDFYDAAKNDAISIYEATDDAGNHYEMTAS
                     NIELGGRKNLPGGGKRIRGQTQFSKPIDPKAKTLFITGDIKTESEPGEIVPLKTKLPVS
                     YKTKHHHVGITIKKIKQQGRRVIVDYQFTGINYSKADEDQLINVGESIGLGNTKKMKTW
                     PSLNEYEKGYYLKGNKAKVTNLKTGEMESVFELDDSTDKDYSLRDFSFDSYALYVNQTV
                     MNLLADDKGITFAVPVRPADGK"
     CDS             complement(2852..3385)
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 106.1;
                     E-value: 2.6e-32)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3388"
                     /transl_table=11
                     /translation="MKEERLIKKAKKGDAAAFEKLITAHQETLYKTAYLYLHHKEDTLD
                     AVQETAYKAFLHIAQLKEPKYFKTWLIRILLHTIFAMRKKHGDVIPFEPQHDTRAENKN
                     IEEYIDLRNALETLDEHIQLTIQLYYFQDFSIAMIAEQTGMAEGTVKTHLHRARKALKQ
                     ELEKEDKHIWKSIK"
     CDS             complement(3704..4936)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 255.4; E-value: 1.1e-77)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_3389"
                     /transl_table=11
                     /translation="MKGIRLRIHPVGWNIILGTLFSRMSVSMSIPFLSIYLTQVKGVSP
                     ALTGIIVSVSSLAGIVMSFYGGYLSDLFGRKIVMITSVFCWALVFVSFMFADSVLAFFV
                     INALNGLCQSIFEPASRALLSDISKEENRLKMFNLRYTAINIGVVFGPLLGLRLGAAKT
                     ALPFLFAGFTYFLYGLSLLFSFRKFKLDENNRKENKTTIATAFNVTRKDKVFLITLLGV
                     ILSISGYAHFSTTLPQYFAAKIEDGVTIFSWLLALNAIVVLIVQYPIVNIMKKFPPIHS
                     IILGNALISFSLLFFSLSSNPFIWGSIVVFFTIGEVLIFSMVDMLVDEIAKPGFKGTYF
                     GAAGFNRLGNVIGPWLGGILLSFFGVNGSFYMFLIIFITTASGIPVLFLAKKHLDKSGH
                     SKVDVTESHRS"
     CDS             complement(5001..6200)
                     /NRPS_PKS="Domain: Aminotran_1_2 (32-388). E-value:
                     1.9e-69. Score: 226.3. Matches aSDomain:
                     nrpspksdomains_ctg1_3390_Aminotran_1_2.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 287.8; E-value:
                     2.2e-87)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3390"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-67, bitscore:
                     226.2, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 9.8e-10,
                     bitscore: 36.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKRLSDRVMNIKPSATMSLNAKTKIMVKEGKDIINMSVGEPDLH
                     PPLTASYAGIQAIVKGKTGYTPAAGLIELRESIVRYLLNERGLEYKPNQIIASAGGKQP
                     LYNVFQAICDQDDEVILPSPYWVSYPEQIKLSGAVPVIVSCDETTNFKITPEKLAEVIT
                     PKTKAVVITSPNNPTGSVYSENELKALGNVLKDYSEIFIISDEIYDQFVYEGKHISLPL
                     IFPELLNRTIITNGFSKVFAMTGWRLGYIAAPSDIAEAIASFQSHATGSPSTISQYAGI
                     SALNGFDKSMVEEYKKRRDILVDGLNQIEGIQCAKPNGAFYAFPNVSQFFGTMFEDQQI
                     IDAETFCHLLLEKQHVSAVPGTAFGEPNNIRLNFAIPKDLITEALKRINNFTTQLAVKV
                     "
     aSDomain        complement(5037..6104)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_3390_Aminotran_1_2.1"
                     /evalue="1.90E-69"
                     /label="ctg1_3390_Aminotran_1_2.1"
                     /locus_tag="ctg1_3390"
                     /protein_end="388"
                     /protein_start="32"
                     /score="226.3"
                     /tool="antismash"
                     /translation="DIINMSVGEPDLHPPLTASYAGIQAIVKGKTGYTPAAGLIELRES
                     IVRYLLNERGLEYKPNQIIASAGGKQPLYNVFQAICDQDDEVILPSPYWVSYPEQIKLS
                     GAVPVIVSCDETTNFKITPEKLAEVITPKTKAVVITSPNNPTGSVYSENELKALGNVLK
                     DYSEIFIISDEIYDQFVYEGKHISLPLIFPELLNRTIITNGFSKVFAMTGWRLGYIAAP
                     SDIAEAIASFQSHATGSPSTISQYAGISALNGFDKSMVEEYKKRRDILVDGLNQIEGIQ
                     CAKPNGAFYAFPNVSQFFGTMFEDQQIIDAETFCHLLLEKQHVSAVPGTAFGEPNNIRL
                     NFAIPKDLITEALKRI"
     CDS             complement(6258..7142)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 264.8;
                     E-value: 1.5e-80)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3391"
                     /sec_met_domain="phosphonates (E-value: 5e-108, bitscore:
                     358.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates-like (E-value: 3.1e-126,
                     bitscore: 417.8, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2e-67, bitscore:
                     225.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNRKSSIFRDALNSKGLVKVAGAHDGLSAKLAEKNGFNAVWASG
                     LGISAVQTVPDASILTMTEFLEAAVIMNESCNLPVIADCDSGYGNIHNVTRMIKKYEAA
                     GIAGVCIEDKVYPKLNSFDDRQQILVSTEEFCAKIRAAKMAQQNDDFVLIARVEALIAK
                     LGQEEAYTRAKAYVHAGADAILIHSKEQSPDEIIEFVNNWDVDAPLVVVPTKYPTLSME
                     QLEKLGVKVSIYANQALRASVKAINDTFESIINNKSSLQIENDIVSVNEIFDIQDVPGM
                     KQLERLIHRQPAN"
     CDS             complement(7157..8368)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3392"
                     /sec_met_domain="ATP-grasp_3 (E-value: 2.3e-15, bitscore:
                     54.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 1.4e-05, bitscore: 22.6,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.1e-09,
                     bitscore: 35.9, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 7.4e-09, bitscore:
                     33.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKRLFLIGIPETHIEKAVARAKQLGFDVLLGDTEASLKKYEHL
                     IKEADQKIALDYTNHENLFSVAKEIHDKEPLDAIFTFKEAGLFNVSKLQQAFHLKGNPP
                     SVVQACLDKYTTRRLLKKAGLNSPDFGLCRSVEDVYDFWNTSQHPIILKPRSQQGSIGV
                     IKVEKKEDIEACFKECSKHDEEKSVLAEEFIEGQEISIEAVVCQGKVDIFGVTEKLLYP
                     GTFVESGHISPYKHKEKHQDLYKNLVKEVVHAMGIVFGPLHIEGYHTNKGFVVGEVHTR
                     YGGDNIVTITEIAMKCDMHTPIFAELAGIPYQPERKHAQSEVCAVRFLETNQGVVRAIK
                     GISDLKMMGNVVDFHVNCSVGDRIRPIKNSYDRAGWMIVKGKNEREVNHALHDAIDKIK
                     IIIR"
     CDS             complement(8331..9593)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 72.3; E-value: 7.1e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3393"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.3e-12, bitscore:
                     45.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.1e-07, bitscore:
                     29.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.5e-06,
                     bitscore: 25.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHILFFNATYIKKISTLETAKNLGLTVSVVGPELPEWSRPFVD
                     HYISANTYQIDETIAVLKETAKENPFDGVITFWDRDVVPVAVTARELNLKGSPVEAAER
                     ARNKWKMRQFLNRAQVPHPKYCKFTNWTELYHASIDMEYPLIVKPVGASASKGVFRISK
                     PEDLNRAYQQLLNAAVPENDKMFSFYQNEYIVEEFMNGQEVSIEGVISDGVIHFAGVTE
                     KWTDQYFEEYQHAFPARLPEAVERELFHITSEGIKALELNNCGFHAEVMITEKGCKIIE
                     INGRLGGDFITTHLVPLAKGINITRANLLAVLGETISFEASKRRAACVRFLIADRAGVI
                     EKWEGVESIKEMPGVVEFVLEKQPGDHVGLPPEKFHDSRIAYVITEAEDTEKAIEYAQN
                     ALSEVRCFINGEEKTVPDRDS"
     CDS             complement(9957..11507)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249:carbamoyl phosphate synthase small subunit
                     (Score: 384.9; E-value: 5.4e-117)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3394"
                     /transl_table=11
                     /translation="MTTMTKLVNEMILVLDFGSQYNQLITRRIREFGVYSELHPHTLTA
                     EEIKEMNPKGIILSGGPNSVYDEGSFRCDEKIFELDIPVLGICYGMQLMTHYLGGKVEA
                     ASQREYGKANIQIQGTPDLFKDLPEEQVVWMSHGDLVVQVPEGFTVDATSHHCPNSAMS
                     KKDKKWYGVQFHPEVRHSEYGNDLLKNFVFGPCECKGEWSMENFIEIEMQKIRETVGDK
                     QVLCALSGGVDSSVVAVLIHKAIGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFNMNVIK
                     VDAKDRFLNKLKGVSDPEQKRKIIGNEFIYVFDDEADRLKGIDYLAQGTLYTDIIESGT
                     ATAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTELGIPDDIVWRQPFPGPGL
                     GIRVLGEVTEEKLEIVRESDAILREEVANHGLERDIWQYFTVLPDIRSVGVMGDARTYD
                     YTIGIRAVTSIDGMTSDWARIPWDVLEVISTRIVNEVKHINRVVYDITSKPPATIEWE"
ORIGIN
        1 ggagccgtca cattcgtggt gacaactgac agaagcggcg agaaaaacat cgccagcaaa
       61 aagagaatgc ccgtcacaac agccgcgaag ccggagcgcg cccccgccgc aacgcctgag
      121 ctggattcaa cataagaagt cgttgtagac gtaccgagta cggctccgat aacgattgat
      181 gtcgaatctg ccagaagcgc tcttcccgca cgcggaagtt tgttttcctt catcagcccg
      241 gcctgtgtcg ctacagccac cagcgttccg gccgtatcga aaaacccgac gaacaagaaa
      301 gttaaaatga caatcagcat ttgtacggag aagatatccg gaagatgcat ccacgcctgt
      361 ccgaaagtcg gcgcaagact cggcacgctg ccgacaatgt gcgtcggaac cggaatcagc
      421 ccgcagacca tgccggcaac cgccgtcaga agcattccga taaatacgcc gccgtttacg
      481 cgaagcacca tcagaatgac cgtcacaata acaccgaaaa ccgtcagcag cacagggccg
      541 ctgtgaatat tgccggtaga caccagagtc gatgagttcg cttcaataat gcccgaaccc
      601 tgcaaaccga caaatgtgat aaacaaaccg atacccgcgc cgaccgccaa tttcagctca
      661 ggcggaatcg cattaatgat tttttcccgc aatcccgtca gcgaaagcgc cacgaagata
      721 attccggaaa tcaagacgcc ggaaagcgca gcctgccatg aaatccccat gccgaggacg
      781 acagagaaag caaaaaacgc atttaatccc atacccggcg caatcgcgat cggatacttt
      841 gcaatgagcc ccattaaaat acagccggcc gcagatgcca aggctgtagc ggtgaacacc
      901 gcgccctgat caatttttaa tgcttccgga aatcccttca caccgtttaa agacaatgtc
      961 agcggattga cgaacagaat gtacgccatt gacaaaaagg tcgttaaacc gccgatgatt
     1021 tcattacgat agcttgtccc cagctcatca aactgaaaaa attgcttcaa gccaattgcc
     1081 tccttcattc tctcccattt attctgcccg ttatccgcca aataaaaaac gccccaaata
     1141 catttgggac gcttgactac atacgttcag tctgaataaa taagaatgga ttatttatat
     1201 caaacgattg agattgatcc gtagtcaagc catttacggt agcttggtag aaacttgcgg
     1261 gccatatccc cgccattata cgatatctgc atatttgatt tctgagtcta ttgtatcaat
     1321 tcaattttga aaactcaata aaaaaaaacg aacaatcccg ttaaaaaaat ttggtttatt
     1381 cgttaattga ccaaaaatgg aagacggcaa aagccgcctt cccgacatca ttttccgtcc
     1441 gcaggccgaa ccggcaccgc gaatgtgatc cccttatcat ccgccagcaa gttcataacc
     1501 gtttgattga cgtacaaagc gtatgaatcg aatgagaaat cgcgcaacga atagtcttta
     1561 tcggttgaat catctaattc aaaaacggat tccatttcac ccgttttaag gttcgtgact
     1621 ttcgccttat tccctttcag ataatagcct ttttcatact cattaagcga tggccaggtt
     1681 ttcatttttt tcgtattgcc gagaccgatt gactcaccga cattgatcag ctgatcttca
     1741 tccgctttgc tgtaattaat tcctgtgaat tgataatcga cgatcacccg tctgccttgc
     1801 tgtttgatct ttttgatggt gatgccgaca tgatgatgtt tcgttttata actgacgggc
     1861 agttttgttt tcagaggcac gatttctccc ggctctgatt ctgtttttat atcgcccgtt
     1921 atgaaaagtg ttttcgcttt cgggtctatc ggtttgctga attgagtttg gccgcgtatt
     1981 cttttcccgc cgccgggaag attctttctg ccgccaagtt caatattcga cgccgtcatt
     2041 tcataatggt ttccagcatc atccgttgcc tcgtaaatcg agatggcatc atttttggct
     2101 gcatcataga agtcgataga atacaggaga gccgatcccg tcgttccgtt ttccgccctg
     2161 atatcgaaaa agcggtataa tccgtgattt acattcacgg ctttcgttcc ttccagagaa
     2221 acggactttt gttttttaat aggtagtgta aagcgccagt ttccggggat atccttgatt
     2281 tgtgtaatga caagcggaag cttatcaccg tctttcagct ttgagccgtc cgtgaacagg
     2341 cgaagctgtc ccgcgtactg cccgtctttc atttttttca tatcactgtt gtcataatcc
     2401 tctgctaaca tattccatgg atctttataa tcaacttgaa aagagatgct ctcctcatct
     2461 gatttcaaat tgtcaacggt aaaattgtaa acgagctgtc cgctgtcgta atacacactt
     2521 ttcactgtca ccgtgattcc gcgtgattcc gctttctcat tcagttttgt caccaaattg
     2581 cttttaaaca gcgcagaacc tgccttatcc tgaaacagac tgtaaatttg tccggcaaca
     2641 ggaatgtttc ccatagccgt attaacggag ggcatgaata agcctgagga cagatacaga
     2701 ataaacaaag cagcagcaac cgcgagtccg tttatcagtt ttcttcccca tctccgtctg
     2761 acggcgcctt cttttccggc acggacagcg gcgctgtgta tcacattttt caattcagct
     2821 ttcggcacgt caatgtcctg atacaattgc ttcatttgat gcttttccat atatgtttat
     2881 cctccttttc cagctcctgc ttcaatgctt ttctcgccct gtgcagatgc gttttcacag
     2941 tgccttccgc cataccggtc tgttcagcga tcatagcaat cgagaaatct tgaaaataat
     3001 aaagctgaat ggtcagctgt atatgttcgt caagcgtttc cagggcattc cgaagatcta
     3061 tgtattcttc aatgttctta ttctccgcgc gcgtatcatg ctgcggctca aacgggatga
     3121 cgtctccgtg ctttttcctc atcgcaaaaa ttgtatgaag caaaatccgg atcagccacg
     3181 ttttaaaata tttcggctcc ttcagttgcg cgatatgaag aaaagccttg taagccgttt
     3241 cctgaacagc gtccagtgta tcttccttgt gatgcaaata gagataagct gttttatata
     3301 aagtctcctg atgagctgtg atcagttttt caaaggctgc ggcatcacct tttttcgcct
     3361 ttttgatcaa tcgttcttcc ttcaccttat ccacctccta tgctgttaga tatgaatcaa
     3421 ggcaaaacgg tttcaaaaag atgaaaaaaa aacgcctcaa agtctaattt cggataacaa
     3481 cgatccgttt tcaaacttga aggtgttttt tatttgtctc atcttatggg gtcagtccct
     3541 tagattaata ccttctttgt tcgccgttca gtctgtattc ctctccccaa aaatataaac
     3601 actcttgttt cccattctga tggggcgctg ctgaaaagaa aaaagccttt aaacctttga
     3661 ggttcaaaga ctttgccatt aattcttcat tgtgttaaaa catttaactc ctatgagatt
     3721 ctgttacatc aacttttgaa tgtccgctct tatcaagatg tttttttgcc aaaaataaaa
     3781 ccggaattcc cgaggctgtc gttataaaaa tgatcaaaaa catatagaag gacccgttta
     3841 caccaaaaaa ggaaagaaga atccctccca gccaaggacc gattacattt cctaaacggt
     3901 taaagcctgc tgctccaaag tatgtccctt tgaagcctgg ttttgcaatt tcatccacca
     3961 gcatatcaac catcgaaaaa atcaaaactt cccctattgt gaaaaacacg acgatagagc
     4021 cccatatgaa tgggttggac gatagcgaaa aaaataataa actgaaacta attaaagcat
     4081 ttcccagaat gattgaatga atcggcggga actttttcat gatattcaca atagggtatt
     4141 gaacgattaa gacgacaatt gcattcaaag ctaaaagcca tgaaaatatg gtcaccccgt
     4201 cctctatttt ggcggcaaaa tattggggca atgttgtaga aaagtgcgca tatccggata
     4261 ttgataatat cactccaagt aatgtgataa gaaaaacctt gtctttcctt gtcacattaa
     4321 aggccgtagc aatagtcgtt ttattttctt ttcgattgtt ctcgtctaat ttaaattttc
     4381 ggaatgaaaa taagagagat agaccataaa gaaaatatgt aaaacctgcg aacagaaatg
     4441 ggagagccgt cttggcagct cccaatctaa ggcctaaaag aggaccgaaa actacgccga
     4501 tattaatcgc agtataccgc aaattaaaca tcttcaaacg attttcttct ttgcttatat
     4561 cggataataa tgctcttgac gccggttcaa agatagattg acacagcccg ttaagcgcat
     4621 tgatgacaaa aaatgcgagt acactatctg caaacataaa acttacaaaa acaagcgccc
     4681 aacaaaatac agacgttatc atcacaattt tcctgccaaa aagatcagac aaataccctc
     4741 cgtaaaagct cattacaatc ccagccagcg aacttactga aacaatgatg ccggttaaag
     4801 caggagaaac accttttact tgtgttaggt aaatagaaag gaagggaatg ctcatcgaga
     4861 ctgacattct gctaaacaag gtgcctaaaa tgatattcca gcccacaggg tgaattctta
     4921 atcgtatgcc tttcaaaaaa ccacctgcct aaacattaga tgcagatata aagaggctcg
     4981 tttaagcttt cagcgctctt ttatacctta actgccagct gagttgtaaa attattaatt
     5041 cttttcaaag cctctgtgat aagatccttt gggatggcaa aattcaaacg aatgttgttc
     5101 ggctctccga atgctgtgcc gggaacagct gacacgtgct gtttttccaa cagaagatga
     5161 caaaatgtct ccgcatcaat tatttgttga tcttcaaaca ttgttccgaa aaattgtgaa
     5221 acattcggaa acgcataaaa ggctccattt ggtttggcgc attgaatgcc ctcaatttga
     5281 tttaaaccat cgactaatat atcgcgtctt tttttgtatt cttcgaccat cgacttgtca
     5341 aaaccgttta aagcagaaat accggcatat tgagaaatag ttgacgggct gcctgtagca
     5401 tggctttgaa agctggcaat ggcttcggct atatccgatg gggctgcgat atagccgagc
     5461 ctccatccag tcattgcaaa gactttggaa aatccattcg ttatgatggt ccgattcagc
     5521 aattcgggaa aaatgagcgg cagactgata tgcttgccct catacacaaa ctgatcataa
     5581 atttcgtcgg aaatgataaa aatttcagaa taatctttca acacatttcc taaagctttc
     5641 agttcatttt ctgaataaac ggaccctgtc ggattattgg gagatgtgat aacaacagct
     5701 tttgtcttag gggtaattac ttctgcaagc ttctcgggtg tgattttaaa atttgtagtt
     5761 tcatcacagc ttacaataac aggaaccgcc cccgacagtt tgatttgttc cggataagat
     5821 acccagtaag gtgaagggag gataacttcg tcgtcttgat cacaaattgc ttgaaaaaca
     5881 ttatatagcg gctgttttcc cccggcagat gcaattattt ggtttggttt atattctaaa
     5941 cctcgttcgt taagcagata tcgcacaatg gattctctta attcaatcag ccctgctgcc
     6001 ggcgtatacc cggttttccc cttcactatt gcctgaattc ctgcatatga ggctgttaat
     6061 ggcggatgaa gatccggttc tccgacactc atatttataa tgtcttttcc ttcttttacc
     6121 attatcttcg ttttggcatt taatgacata gtggccgaag gttttatatt catgactcta
     6181 tcggataatc ttttattcaa ttcaaacgcc tccaatgtct ttatgggcca ttcttaaaat
     6241 agcacgatac aaaaacctca gttagccggc tgtctatgga tcaaacgctc cagttgcttc
     6301 atccccggaa cgtcttgaat gtcaaatatc tcattaacgc tcacgatgtc attttcaatc
     6361 tgcaaagacg atttattatt tataatgctt tcgaatgtat catttatagc cttaacagaa
     6421 gcgcgcaacg cctgattcgc atagatggaa accttcactc ccaatttctc aagctgttcc
     6481 attgagagcg tcggatattt agtcggaacc acaaccaacg gcgcatccac gtcccaattg
     6541 ttaacaaact caataatttc atcaggcgat tgttcttttg aatgaattaa aattgcatct
     6601 gctccagcat gaacataagc ttttgctctt gtataggctt cttcttgacc caatttagca
     6661 attaaagctt cgacacgggc aatcaataca aaatcgtcat tttgctgagc catctttgcg
     6721 gctctaattt ttgcgcaaaa ttcttcagta ctgacaagga tctgttgtct gtcgtcaaat
     6781 gagtttaatt ttggatatac tttatcttca atacaaactc cggcaatacc agcagcttcg
     6841 tattttttga tcatgcgggt gacattgtga atgttcccgt agccggaatc acagtcagcg
     6901 atgaccggca aattgcatga ttcattcata atgacggcgg cttcaagaaa ttcagtcatc
     6961 gttaatatac tggcatcagg tacagtttgc acagccgaga ttcccaaacc gcttgcccat
     7021 acggcattaa atccgttttt ctctgctaat ttggcgctta aaccgtcatg agctcccgca
     7081 actttcacca aacctttact gtttaaagca tctctaaaaa ttgatgattt tctgtttttc
     7141 accatcattc tccccttcac ctaatgatta tttttatttt gtcaatcgca tcatgtaatg
     7201 cgtgattgac ttctcgctca tttttcccct ttacaatcat ccatcctgct ctatcgtagc
     7261 tgtttttgat cggtctgatt ctatcaccga cactgcaatt tacatgaaaa tctactacat
     7321 tccccatcat tttgagatcg ctgatccctt tgattgcgcg tacaacccct tggttcgttt
     7381 ctaaaaaacg aacggcgcat acttcgcttt gagcatgttt cctttccggt tgatatggga
     7441 tgcccgccag ttccgcaaaa ataggtgtat gcatatcaca tttcatggcg atttctgtaa
     7501 tggtcactat gttgtctccg ccatagcggg tgtgtacctc gccaaccaca aatcctttat
     7561 ttgtgtgata cccttcaata tgcaaggggc caaatacgat ccccatggca tgaacaactt
     7621 ccttgaccag attcttatac aaatcctgat gtttttcttt atgtttatac ggcgatatat
     7681 gcccagattc tacaaaagtc ccggggtata gcaacttttc ggtcacacca aatatgtcga
     7741 ccttgccttg gcagacaacg gcttctattg aaatttcctg cccttctata aattcttcgg
     7801 ctaatactga cttctcctcg tcatgttttg aacactcttt aaaacacgcc tcaatgtcct
     7861 cttttttctc aacttttatg acgcctatac tgccttgctg agatctcggc tttaaaatga
     7921 taggatgttg agatgtattc caaaaatcgt atacgtcttc cacgctcctg cacaatccaa
     7981 aatcgggaga gtttagtcct gcctttttta aaagccggcg cgttgtatat ttatcaaggc
     8041 atgcttgcac cacagacgga ggatttcctt ttaaatgaaa tgcctgctga agtttggata
     8101 cattgaataa gccggcttct ttgaaagtaa atatggcatc taaaggctct ttgtcatgga
     8161 tttctttagc gactgagaat agattctcat gattggtata atctaatgcg attttttggt
     8221 cagcttcctt tattaaatgc tcatattttt ttaatgaagc ttctgtatct cctaataaga
     8281 cgtcaaaacc aagttgtttt gccctcgcaa cggccttctc aatatgcgtt tcaggaatcc
     8341 cgatcaggaa cagtcttttc ctctccattg atgaaacacc tcacttcaga taaagcattt
     8401 tgagcatatt cgatcgcttt ttctgtatct tcggcttctg tgatgacata tgcaatccgg
     8461 gaatcatgaa acttttcagg cggcaggcca acatgatcgc ccggctgctt ttctaaaaca
     8521 aattcaacga ccccgggcat ttctttgatc gattcaacac cttcccactt ttctatcaca
     8581 ccagcacggt ctgcaattaa aaacctgacg caggcagctc ttcttttcga agcttcaaag
     8641 cttattgttt ctcctaatac agccaatagg tttgcgcgcg ttatatttat acctttggct
     8701 agaggaacca aatgggtagt aataaaatcg ccgcccagac gaccgttgat ctcgataatc
     8761 ttgcaccctt tctctgtgat catgacctcg gcatgaaaac cacaattgtt cagctccaaa
     8821 gcttttatcc cttcactggt gatgtggaat aattcacgtt ccacagcctc cggcagcctg
     8881 gcgggaaatg catgctggta ttcttcgaaa tactgatccg tccatttttc agtaacacct
     8941 gcaaagtgaa tgactccgtc ggaaatcact ccctcaatgc tgacttcttg tccgttcata
     9001 aactcttcaa caatatactc gttttgataa aaagaaaaca ttttatcgtt ttccggcacc
     9061 gcagcgttta acagctgctg atatgcgcga tttaaatctt caggctttga tattcggaat
     9121 acgcctttac tggcagaagc acccacaggt ttaacgatca atgggtattc catatcaatg
     9181 cttgcatgat ataattcggt ccaatttgta aatttgcaat attttggatg aggaacttgt
     9241 gcgcggttca aaaattgacg catcttccat ttgtttcgag cccgttctgc cgcttccacc
     9301 ggactgccct ttaagttaag ttctcgggca gttaccgcca ccggaaccac atctctatcc
     9361 cagaatgtaa tgactccatc aaaaggattt tctttggcag tttccttcag aacagctata
     9421 gtctcatcaa tctgataagt atttgcggaa atgtaatggt caacgaatgg ccgcgaccat
     9481 tcaggcagtt cagggccgac aacagaaacc gtcaagccca aatttttagc agtctccaaa
     9541 gtagaaattt ttttaatata agtagcatta aaaaataaaa tatgtttttc catccttccg
     9601 agcctctttc aacatttttt tctgcaaatt agaaaccttc tgcgtttcta aagaactgaa
     9661 tgcagaagat aaaaaacccc cttggaaaac acaaaccatc atatgtttta tttgtatata
     9721 ttcataataa catacattat ttgttattaa atgaatattt tatgaattca gttttattag
     9781 aaaaattgag attataggga gaatattagg aatacaactg attaaaaaac tcgaatatat
     9841 aaaaaactgc tgcacatctt ctccggtgtt aatgataaaa ggcccattat tcctagaacc
     9901 atgtaaatta aaaaagcctc aaatctttat aaataaaaga tttgaggctt ttctcattat
     9961 tcccactcaa ttgttgcagg cggcttgctc gtaatgtcat acacgacgcg gttgatgtgt
    10021 ttcacttcat tgacgatccg tgtcgaaatc acttcaagca catcccaagg gatacgcgcc
    10081 cagtcagatg tcatgccgtc aattgatgtt acggcacgga taccgattgt gtaatcatac
    10141 gttctcgcat ctcccatgac gccgacgctg cggatgtcag gaagaaccgt gaagtactgc
    10201 cagatgtcgc gctcaaggcc gtggttcgcc acttcttcac gcagaatcgc gtctgattca
    10261 cgaacgatct caagtttttc ttccgttact tcgccgagta cgcggatgcc aagtccaggg
    10321 cccgggaacg gctgacgcca tacgatatca tccgggatgc cgagctctgt gccgagcgcg
    10381 cgcacttcat ctttgaaaag agtgttcagc ggttcgatca gttcaaattg catatcttca
    10441 ggaagtccgc cgacattgtg gtgcgatttg atcgtttgcg cagttgccgt tccgctttca
    10501 ataatgtctg tgtaaagcgt tccttgcgca aggtagtcga ttcctttcag cctgtccgct
    10561 tcatcatcaa atacgtaaat gaattcgttg ccgatgattt tgcgtttttg ctcaggatca
    10621 gaaacacctt tcagcttgtt taagaatctg tctttcgcat caactttaat gacattcata
    10681 ttaaagcctt cgctgaacgt tttcatgacg ccttccgctt cgcctttgcg gagaaggccg
    10741 tgatctacga aaatacaagt cagctggtcg ccgatcgctt tatgaatcaa aacggctacg
    10801 acagaagaat cgactccgcc gctcaaagcg caaagcactt gtttgtctcc gacggtttcg
    10861 cggatttttt gcatttcgat ttcgataaag ttttccattg accattcgcc tttacattca
    10921 caaggcccga agacaaagtt tttcagaagg tcatttccgt attctgaatg acggacttcc
    10981 ggatggaact gaacaccgta ccattttttg tcttttttgc tcatcgccga gttcgggcag
    11041 tgatggcttg tcgcgtctac cgtaaaccct tccggcactt gtacgactaa gtcgccgtgg
    11101 ctcatccaga caacttgttc ttccggaaga tctttgaaca agtcaggagt tccttgaatc
    11161 tgaatgttcg cttttccgta ttcgcgctgg cttgccgcct cgactttccc tccgaggtaa
    11221 tgagtcatca gctgcatgcc gtagcagatg cccaatacag gaatatcaag ttcaaagatt
    11281 ttttcatcac agcggaaaga tccttcatca tatacactgt ttggtccgcc tgaaaggata
    11341 attccttttg gattcatttc tttgatttcc tcagctgtca acgtatgggg atgcagctcg
    11401 ctatatacgc caaattcacg gatccggcgg gtaatcagct ggttatactg actgccgaaa
    11461 tcaagaacaa gaatcatttc attcactaac ttcgtcatgg ttgtcaccta atctcctcta
    11521 agtttttgac acagaaaaaa cggaggacac acgttcagcc ctctgtcgcg caagacttgt
    11581 ccggaagccc ggctttttaa cgctcccggg ctcccattta acattcattt attctaacaa
    11641 caggacgata tgcggtcaag actatcttct tttaattata ttttcccaca actgtcccga
    11701 ttcattccaa agctccgctg cattatccct gcggtataag gcccgctcat agagcagcgt
    11761 cagctcggac atgtcgtttg tatggtacgc ctcgtcaatc ctcgcggcaa aatcgcgcag
    11821 cgtttctccg tctcccctgc tgaatccttt tcgtttcagc tggcggagca gcgcggcata
    11881 tgcgtcgaaa aagacgtctt cacccgttcg ccgcttcaat ctggctgctg taacgtgcgg
    11941 aatccagcgc gcccggagca cccaggcgag tgccgccgcg gctgaaatca cgataacgat
    12001 ggctgcatac ggccacaggt gtgccgcggt tttgttgcgg atcacaggct gcggtgccgc
    12061 acggtgatcc cgctttttcg gtgttttttc tttttccggc tttgtttcct gacgctgctt
    12121 gtcagacggt gaatccgaat tc
//
