LOCUS       gnlProkkaDCPIMBAF_47   12238 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DCPIMBAF_47.
ACCESSION   gnlProkkaDCPIMBAF_47
VERSION     gnlProkkaDCPIMBAF_47
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 01:44:32
            Original ID  :: gnl|Prokka|DCPIMBAF_47
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2275
            Orig. end    :: 14513
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12238
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10285]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10285
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12238
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12238
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(65..475)
                     /locus_tag="ctg47_3"
                     /transl_table=11
                     /translation="MILYNSLLAKIILNRKRNKREHYFMVFGCCFTRYKYLEIWEDMEL
                     RIHERQYFECFLLALMPSLVLSLLFSWWFMLLALFSYHLLYWAERWFGHHSSFDWEALE
                     YCGDTLYLRKRKFCAWMKWYGKRTLPPSEWED"
     CDS             complement(931..2121)
                     /locus_tag="ctg47_4"
                     /transl_table=11
                     /translation="MVRNLFLTTLCALAFCPAFAQTSTTEEKVEYSEDKYKVETNRFWS
                     NWLISAGGGAQIYFGDHDKQVSFGKRLAPALDIAVGKWFTPGIGMRLMYSGLQQKGATQ
                     KGALSHSTGGDVPGKGGNGYWLEKQKFDMANFHADILFNFSNLFCGYNEKRIWNCSPYA
                     GLGWARVWKSPSAKEVSANVGILNSFRLCSALDLNLDVRAMLVNDRFDGEGGGRFNEGM
                     LSATVGLAYKFKPRGWDRSKTIYRYDYGDLESMRRKLNEMSAENERLKKALAEGNVQDA
                     RTIIKKIAAANLVTFPINKSKLDNEARANLGMLAEIIKSGDPEATYTITGYADAGTGSK
                     KGNEKLSKERAHAVYDCLVKEFGVKESQLRIDYKGGVENMFYNDPRLSRAVITRSE"
     CDS             complement(2321..4414)
                     /locus_tag="ctg47_5"
                     /transl_table=11
                     /translation="MKIQMKHFISGCALFVTVLTACSDDDFEGKTSIKSGDAVQFAASS
                     RTSTRTVYDDENIFQINWEEQDKIKIYSNKTYEGVADADYTVTPIETEDPQKSTNKLYN
                     EGTIAAFGTSQLMWADNDTHKFIGVYPSDNSNISVDAETGIVTLPINRNQRCEVVAVSG
                     NDYYSQRYSDYTYYAKPDMKNAYLVAYNALTPEQAATNDGNVFLDFKPVMTTIEVVVKG
                     RANVNEEDVQVTGISVVREVPEGDGDTFTWNAETGETTNKLPESSKGMNTQSTTTFVGL
                     KTSDNTNIVTLKNNESIVFTVFLPPYAIDGNWPMKIRVHATGATEIITKDISGILASNK
                     RRVTLPNFKSSNEQIGNNWITPLDDNIYVSQLSIPGTHDAATGDGTTFSLGKTQDMTLD
                     QQFEMGIRAFDLRPALNASSTMILCHGIVATTFVWDNVMERFKYYLKENPGEFIIAIMR
                     HEDEYSGISLTHWTNENTHEKWAPAMLEKLNVMKNTINPSTNQSYTIDFRPDLTVGEMR
                     GKILFMCRSWTKYNDAGPVVGGYHDWSHSKDGGEVSIWGPSSVIGTLNIQDCYNRSEAG
                     VSSDEFSTVKWNAIEALLEKSRYFHTNPAMINRWSYNHTSGYTSGIIATASSTDGYREN
                     AANNHIKFYNKITSTDWVGSTGIILSDFVGARRSGNFTVYGDLLPQAIINNNYKYRMKR
                     KGE"
     CDS             complement(4446..4643)
                     /locus_tag="ctg47_6"
                     /transl_table=11
                     /translation="MKEQKKKKYEAPETKKTQVELEDGICAASRTGKPVVDDKNDKVNI
                     SEQGHGGWNGIGDDISGEWQ"
     CDS             complement(4811..7141)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216:exopolysaccharide biosynthesis domain protein
                     (Score: 277.2; E-value: 4.3e-84)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_7"
                     /transl_table=11
                     /translation="MNEQNRNNQDINLKDLFFYLLSKWRWFLLSILVFGSLSWLRYAQS
                     PFVYFRQATVIIKDPSNKTTTAGLDRYDNYINKVNVANEILQFRSKKLMQEVVKRVHAD
                     ISYLHKEGLRENELYTKAPVAVVFPDATPEQYLSFKVTPRDKQTVTVSDFMGTEKDKVC
                     QVGLNDTVDVNGVRMVISPTNYYTDAWLEKIVRVQKNPLAAVAGYYRGNLGIRQEEDDS
                     SILTLSLKDSSPIRAEDVLNMLITVYNEEAVRDKNQVAVNTADFINERLIIISRELGGV
                     ETELETFKRDNRIMDISSTASSYMSESQQSNSQVLELETQLRLARYIKDYLEDHTKGTD
                     LIPSNTGIDNASIENQISQYNTIKLRRDKLIDDSSDSNPVVEELNNSLHAMKQSIIRAV
                     DNMIVSINVRRNDARSREMRAQSRVSSIPTKEREMLSIERQQKIKEALYLFLLNRREEN
                     ALSQAMADNNARVIDGADGSTVPIAPSGKRILLLGVLIGFALPCIVFLVRMFMDTYVHS
                     RKDLKGKVSVPFLGEIPLDKETAKSGRKGASINEKEDDIVSEAFRILRTNMSFMEKKDS
                     RMQVITFTSFNEGAGKTFISRNLGMSLVYAKKRVLLLDMDIRKGTLSRHFHKHKLGLTN
                     YLANSSIGIDDIIHHDGNQPGLDIISSGTVAPNPAELLMDERLDELVKELRTRYDYIIA
                     DSVPVGIIADATIANRIADLTIFVVRAGKLDRRQLPDIESLYQEKTLNNMTLVLNGVDV
                     SHRGYGYGYGYGNYGYGKYEKKK"
     CDS             complement(7156..7953)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 81.2;
                     E-value: 9.8e-25)"
                     /gene_kind="transport"
                     /locus_tag="ctg47_8"
                     /sec_met_domain="Poly_export (E-value: 1.9e-17, bitscore:
                     52.9, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKKMIFISCMAVLLLSSCASRKGIAYLQDMELGQRYLYDARYEA
                     TVHRNDRLSITVNCKRPELAIPFNAHGNSIHVGADGNVSTSSGEVSAESAKGYRVDVEG
                     NIDFPILGKLHVEGLKVSEVTDLIKNRIIQGNYIKDPQVSLEFLNFKYTVLGAVGRTGT
                     FTVKDDRITLLEAIANAGDLSSKAKINSVAVIREIDGEREIFVHDLRSKELFTSPCYYL
                     QQNDIVYVEPRYRKKDSEDRGFQVGSIFLSLASVIVSLIWALK"
     CDS             complement(7974..8879)
                     /locus_tag="ctg47_9"
                     /transl_table=11
                     /translation="MMREYDFRVAGFLFKLHLPEEQDIDRLLPSFRPFRCVTDIQGRAI
                     FNFVAVSSSLSEKGIIRVLEETESDLGHIRLLEMAEGYRVELRYTAGSPVHVLHAEPFF
                     TLAMANIRWDDPYAGEVLCSLLRIVYSQAILFWGGISVHASAVAWRGKAYLFMGKSGTG
                     KSTHAVQWLKCFPKSELLNDDNPTIRMESGRSIAYGTPWSGKTPCYKNRCFPVGGIVRL
                     RQADANRFVLQKDVDAFITLLPGCSAIRLHSYLCNGMYDTLAETVSAVPVGELDCLPDE
                     GAALLCEESLTKEYEYLYNH"
     CDS             complement(8876..9964)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_10"
                     /sec_met_domain="NTP_transf_5 (E-value: 6.5e-38, bitscore:
                     120.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYPNKEVTILFILLRAGLWEKEPESLSLFPLSGESWENIYRMARR
                     QTVTGLVYRGVCHLPDEMLPPEKLLVRWVAEINAIEQRNHRMNAVLAELYEMFRNDGLT
                     PVLQKGQSAALFYEFPLLRECGDIDFYFPYKNEREFAIRIVKNRGIRVDWQPDDSVSYI
                     WNSIEVEHHPRMLDLYNPFLHEDLNSLETLFGYHDVWLSPGCEITIPSPTLYVLLLNTH
                     IMKHAIGRGIGLRQLCDMARACHRLHIAVTSSEIKNICCKAGIIGWNRLLHSFLVEHLG
                     LPVTSLPYKDRPVSSRPLLERVLEGGNFGQYRMERTPGTQAVWQRKLYTAHSFLRNVSL
                     SFGYAPKEAFWTFTNLLTGQVK"
     CDS             complement(10001..10285)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_11"
                     /sec_met_domain="PF05402 (E-value: 2.6e-17, bitscore: 52.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 8.2e-09,
                     bitscore: 25.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKTGLMKLQPNLQLRKIGNKYMIVSTASGNVNMTDVFTLNETAA
                     RLWQLMEGKDITPKELAVLLCNEYEVGEEDALKDVEKQLCEWKQSGLVG"
     CDS             complement(10298..10963)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 225.9; E-value:
                     1.7e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_12"
                     /sec_met_domain="Bac_transf (E-value: 2.4e-65, bitscore:
                     209.1, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKVEVVSKAVKGSATERSRSGDIMSPIARTTKRFLDVVASIVGL
                     AVFSPVLLVIYIAIKCEDHGKAIFSQERVGYHGEIFTLYKFRSMITLAEADGKPALCQK
                     RDKRLTRVGRFLREHHLDELPQLWNVLKGEMSFVGPRPERKYFVDQIKSINPDYEQLYQ
                     LRPGLFSAATLYNGYTDSMTKMLERLRMDLDYLYHRSLWFDTKIIFLTVFSILVGKKF"
     CDS             complement(10951..12075)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 141.8;
                     E-value: 5.7e-43)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_13"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.7e-36,
                     bitscore: 115.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALKILQLGKFYPIMGGVEKVMYDLMSGLSERGVPCDMLCALSQ
                     GSSRTFSINAHSRLIGCRTWMKVAATMISPDMIFSLRKRCRDYDIIHVHHPDPMACLAL
                     FLSGYKGKVILHWHADIEKQKILLKLYSPLQEWLLTRADVIIGTTPPYLAESPCLARVR
                     HKMECLPIGIEPVCPAPAAVEEVRKRYPGKKIIFSIGRLVAYKGYKYLIESAHYLDDDY
                     VILIGGSGAMKYDLEAEIETWGVQDKVMLLGRISDKELSAYYGACTLFCLSSVQKTEAF
                     GIVQIEAMSCGKPVVATNIPHSGVSWVNAHGFSGLNVTPCSAKELAGAIMTITRNDDLY
                     QKLAKGARERYQETFTKEKMIDNILEIYRSLWKK"
ORIGIN
        1 aaccaactga caaacactag atatgtacca atagcattgc cagtgatctt tatatttaca
       61 gtatttaatc ttcccattct gagggtggca atgttctttt tccataccat ttcatccagg
      121 cacagaattt tcgtttcctt aaataaaggg tatcaccaca atattccagt gcttcccagt
      181 caaacgagga atgatgtccg aaccatctct ctgcccagta aagtaaatga taactgaata
      241 gtgcaagcaa cataaaccac cacgaaaaaa gcaacgatag taccagtgaa ggcattaatg
      301 ccaataaaaa acactcaaaa tactgacgtt catgaattcg taattccatg tcctcccata
      361 tttccagata tttataacgg gtaaaacaac aaccgaaaac catgaaataa tgttccctct
      421 tatttcgttt cctgtttaga ataattttag ctaacagact attatataaa atcataccgc
      481 ttcttatttt tataacaaca aaggaatgga gttaccgaca tatagaaaca taccttatcc
      541 atgtcgctta agtatcatta caaaacaggc actatcaccg ggacaatatt atgctgtggc
      601 taattggatt atgatataaa aatagtttac cccgattccg ttacctgttt tttcaccttc
      661 tctattgtct cattttttct ctcttcaatg tctctacaat tctttaattg aactctcaaa
      721 aaatacttcc aaaccaacca tagcggtcct tgaaacggac taacaggcta gttcacggat
      781 tcagtatcca tagcaaaaat attacattac gtatctgtga taacaaacag tttctttcat
      841 attgttttcc cagctatatt tatttatagg tgggaacata aagaataatg gcctgtccct
      901 atgctttgga caggccctat ttaaaagact ttattcacta cgggtaataa ccgcacggct
      961 caaacgcgga tcattataga acatattctc cacaccaccc ttgtagtcga tacgaagctg
     1021 tgattctttc acaccgaact ctttaacaag gcaatcatag acggcatgtg cacgttcctt
     1081 gctcaatttc tcgttaccct tcttactgcc tgtgcccgca tccgcataac cggtgatagt
     1141 atatgtcgct tccggatcac ctgatttaat gatttccgcc agcataccca aattggcacg
     1201 ggcctcgtta tccagtttgc tcttattaat cgggaaagta acaagattgg ctgcggcaat
     1261 cttctttatg atagtccgag catcctgcac gttaccctca gcaagggctt tcttcaaacg
     1321 ttcattttct gcactcattt cattcagttt acggcgcata ctttccaaat caccgtagtc
     1381 gtaacgataa atggtcttgc tacgatccca gccacgaggc ttgaacttat aggccagccc
     1441 gacagtagcc gacaacatgc cttcattgaa acgtccgcca ccctcaccat caaagcgatc
     1501 gtttacaagc atggcgcgta catcaaggtt cagatcaagc gcgctgcaca aacggaatga
     1561 gtttaaaatt ccgacattgg cacttacttc ctttgctgat ggcgatttcc atacacgggc
     1621 ccatccaaga cctgcataag ggctgcaatt ccaaatacgc ttttcattgt aaccacaaaa
     1681 caggttagag aagttgaaca ggatatcggc atgaaaattg gccatgtcaa atttctgttt
     1741 ctccagccaa taaccgtttc ctcccttccc tggaacatca ccaccggtgg aatgtgacaa
     1801 ggcacctttt tgggtggctc ccttctgctg aagaccgcta tacattaaac gcataccaat
     1861 cccgggagta aaccatttgc ccacagcaat atccaatgca ggagccaaac gcttgccaaa
     1921 tgagacctgt ttgtcatgat cgccaaaata aatttgtgca ccaccgcctg cactgataag
     1981 ccagttgctc cagaaacggt tggtttccac tttgtatttg tcctcactgt attctacctt
     2041 ttcttccgtg gtggaagtct gtgcgaaggc aggacaaaaa gccagtgcgc acaaggttgt
     2101 taaaaacaaa tttctaacca ttttttaaag ttttttttat tttactgcct tatattttaa
     2161 gttgttacta acaactgcct gcaaagccgg accaccatat agtacatagg tcttgaaacg
     2221 tacttcaaaa tgtgtacagc cacatgattc atttttgctg attctttctt ttcatccttc
     2281 tcttcagaaa aggatgaaaa gttcgttgaa caatgtttta ttactcacct tttcgtttca
     2341 tgcggtattt gtagttgttg ttgatgatag cctgcgggag aagatcaccg tacacggtaa
     2401 agttaccact acgacgagca cctacaaagt ctgaaagaat gataccagtg ctgccaaccc
     2461 aatcagtaga ggtaatcttg ttatagaact tgatatgatt gttagcggca ttctcacgat
     2521 aaccatctgt ggaagatgct gtagcaatta tcccactagt atatccagaa gtgtggttat
     2581 aagaccaacg attaatcatg gcagggttag tgtggaaata tcggctcttt tcaagcaaag
     2641 cctctattgc gttccattta acagtagaaa actcatcact agaaacaccg gcttccgaac
     2701 gattataaca gtcctgaata ttcaatgtcc cgataacaga cgacggtccc caaatagaca
     2761 cctcgcctcc gtctttggaa tgtgaccaat catgatatcc acccactaca ggaccagcat
     2821 cgttatactt cgtccacgaa cggcacataa acagaatctt tccacgcatc tcgcctacag
     2881 tcaaatcagg acgaaagtca atggtataac tttgatttgt agatggatta atagtattct
     2941 tcattacatt caacttttcc aacattgcag gcgcccattt ttcatgtgta ttttcattcg
     3001 tccaatgagt taaacttatt ccactatatt catcttcatg acgcataatg gcaatgatga
     3061 attcacctgg attctctttc agatagtatt taaaacgctc cattacgtta tcccatacaa
     3121 atgtcgttgc tactatgcca tgacaaagaa tcattgtgct actcgcatta agtgccggac
     3181 ggagatcgaa cgcacggata cccatttcaa attgctggtc taaggtcatg tcctgagttt
     3241 ttcctaaact gaatgttgtt ccgtcacccg tagctgcatc gtgtgtaccg ggaatggaaa
     3301 gctgcgaaac ataaatatta tcatccaacg gagtaatcca gttgttgccg atttgctcat
     3361 ttgaagattt aaagtttggc aatgtcacac gacgtttgtt actggcaaga atccctgata
     3421 tgtcttttgt gattatttcc gtagcaccag tagcatgtac acgtatcttc ataggccagt
     3481 taccatcaat ggcatatgga ggaaggaata ctgtaaacac aatggattcg ttatttttca
     3541 gtgtaactat atttgtattg tccgaagttt tcaaaccaac aaaagtagta gtactttgtg
     3601 tattcatgcc tttggaactt tcgggcagtt tgttggtggt ttcgcccgtc tctgcattcc
     3661 atgtaaaagt atctccatcc ccttccggca cttcgcgtac aacagatata ccagtaacct
     3721 gtacatcttc ttcgttaaca ttcgcacgcc cctttaccac tacttctatg gtggtcatca
     3781 ccggcttgaa gtccaaaaag acattaccgt cgttggttgc agcctgttcg ggcgtaagag
     3841 cgttatatgc caccagatag gcattcttca tatcgggctt ggcgtaatag gtatagtcgg
     3901 aatacctttg agagtaataa tcattgccag aaacagcgac cacttcgcaa cgctggttgc
     3961 gattgatagg cagtgtcaca attccagttt cagcatctac acttatattc gaattatcac
     4021 tgggataaac accgataaat ttgtgcgtat cattgtctgc ccacatcaat tggcttgtcc
     4081 caaatgcagc aatagtgcct tcgttataaa gtttattagt ggatttttgg gggtcttccg
     4141 tttcgatagg cgtaaccgta tagtctgcat cagccacccc ttcataagtc ttgttactgt
     4201 aaatcttgat tttgtcttgt tcttcccagt taatttggaa gatgttctca tcgtcataga
     4261 ctgtccgggt agatgtacgg gacgaggctg caaattgaac tgcgtcaccg gactttatag
     4321 aagttttccc ttcaaaatcg tcatcgctac atgcggtcag cactgtaaca aacaacgcac
     4381 aacccgaaat aaaatgcttc atttgtatct tcataatctt atttctttta gtttacaatc
     4441 gttttttatt gccattctcc ggagatatca tcaccgatgc cattccatcc tccatgtcct
     4501 tgctccgaga tgtttacctt gtcgttcttg tcatccacaa caggctttcc tgtacgggaa
     4561 gcggcacaga ttccgtcttc caattccacc tgagtcttct tcgtctcagg tgcttcatac
     4621 ttttttttct tctgttcttt cattgcgata ttatttaaag aattaaacat agttctcatt
     4681 aaaaaaagac gattttcaca aacagtcttt ttcgagttga agcccttgtt tataacagaa
     4741 ttcttttctt cgccaagata aaatcctgag ttagggaaag gtactccaac atttatttgg
     4801 ggaatttata tcatttcttc ttttcatact tcccgtaacc atagtttcca tatccgtaac
     4861 cgtatccata cccccgatgg cttacatcca caccatttaa caccaacgtc atattattca
     4921 gggttttctc ctgatacagg ctctcaatgt ccggtaactg gcggcgatcc aattttccgg
     4981 cacgtaccac gaaaatggtc agatcggcaa tacggttagc tatcgtagca tcggcaataa
     5041 tacctaccgg cacgctgtcg gctatgatgt agtcataacg tgtacgcaac tcctttacca
     5101 gttcatccag acgttcatcc attagcaatt ccgccggatt gggagccacc gtccctgaag
     5161 atataatatc cagacccggt tgatttccgt catgatgaat tatatcatca attcctatac
     5221 tactattagc caaatagttg gtcagtccca atttatgttt atggaagtgc cggctcagtg
     5281 ttcccttgcg gatgtccata tccagcagca gtaccctttt ttttgcataa acgagactca
     5341 tacccagatt acgcgaaata aatgtcttgc ccgcaccttc gttgaaagaa gtaaaagtaa
     5401 taacctgcat cctgctatct ttcttttcca taaaggacat attggtccgc aaaatgcgaa
     5461 acgcttccga cacaatatca tcttccttct catttatgga agcccccttc cttccacttt
     5521 ttgcagtctc cttatccagt ggtatctccc ccaaaaaagg aacgcttact tttcctttca
     5581 agtccttacg gctatgcaca taagtatcca taaacattct gacaaggaat acaatacatg
     5641 gcagggcaaa gcctattaac actcccaaca acagaatacg ttttcctgaa ggagctatag
     5701 ggacagtact gccgtcagca ccatcgatca cgcgtgcatt attatcagcc attgcttgtg
     5761 agagtgcgtt ttcttcccga cggttcaaca aaaacaagta tagtgcctcc tttattttct
     5821 gttggcgttc aatggaaagc atttcccttt ccttggtcgg aatggaagat acacgtgact
     5881 gtgctctcat ttcccggctt cgggcatcat tacgacgtac gttgatacta acaatcatat
     5941 tatctaccgc acgaataatg ctctgtttca ttgcatgcag tgaattgttc agttcctcca
     6001 ccaccggatt gctgtcactg ctgtcgtcta tcagcttgtc acgacgtaac ttgatggtat
     6061 tgtattggct gatctggttc tcaatgcttg cattgtcaat gcccgtattc gaaggaatca
     6121 gatcagtccc ttttgtatgg tcctccaaat agtccttgat gtaacgggcc agccgaagtt
     6181 gggtttccag ttccagcacc tggctgttcg actgctgtga ttcgctcata tagctgcttg
     6241 ctgtagaact gatgtccata atccggttat cacgcttaaa ggtttccagc tccgtttcca
     6301 cccctcccaa ttcacggctg atgataatca gtcgctcatt gataaagtcg gccgtattca
     6361 cagctacctg attcttgtca cggaccgcct cttcgttata tacggtaatc agcatattca
     6421 atacatcctc agcacggatg ggagaactat ccttcagcga caaggtgagg atagaggaat
     6481 catcctcttc ctgacgaatg cccagattcc cacgatagta acctgcgaca gccgccaacg
     6541 gattcttctg caccctgaca atcttttcca gccatgcatc cgtataataa ttcgttggag
     6601 aaattaccat ccggacaccg tttacatcaa ccgtatcatt caagcccacc tggcaaacct
     6661 tgtctttttc cgttcccata aaatcagaaa ctgttaccgt ctgcttgtca cggggagtca
     6721 ctttaaagga tagatattgt tccggtgtcg catcaggaaa gaccaccgct accggtgcct
     6781 tggtgtacag ttcattttca cgcagccctt ccttgtgcag gtaactaatg tcggcgtgta
     6841 cccgttttac cacttcctgc atcagtttct tcgagcggaa ttgcagaatc tcattagcta
     6901 cattcacttt attgatataa ttgtcgtaac ggtcaagccc tgccgtagtg gttttattgg
     6961 acggatcctt gatgatgacc gtggcctgac gaaaatagac gaaaggagac tgtgcatacc
     7021 tcagccatga cagggagccg aacaccaata tggatagcag gaaccatcgc catttggaca
     7081 aaagataaaa aaacaggtct ttcagattga tgtcctgatt gtttctgttc tgttcattca
     7141 ttttttcaat tctccctatt ttaatgccca aatcagtgag acaatcacgc ttgccagtga
     7201 aaggaaaata cttccaacct gaaatcccct atcttccgaa tccttcttac gatatctggg
     7261 ctccacatat acaatatcat tttgttgcaa ataataacac ggagaggtaa acagctcctt
     7321 gctgcgcagg tcatggacaa aaatctctct ctcaccgtca atctcgcgaa tcaccgccac
     7381 tgaattgatt tttgctttcg aactcaggtc tccagcgttg gctatagctt ccagaagggt
     7441 aatacggtca tccttgacag taaatgttcc cgtacgacca acagctccca ataccgtgta
     7501 tttgaaattc agaaattcca gcgatacttg cggatcctta atgtagtttc cctgaatgat
     7561 ccggttcttg atcaggtccg tcacttcact tactttcagc ccttccacat gtaatttgcc
     7621 taaaatggga aaatcgatat tcccctccac atccacacga tatcctttag ctgactcggc
     7681 agaaacctcc cccgatgaag tcgatacatt cccgtcagcc cccacatgga tactgttgcc
     7741 atgggcattg aaaggaatgg ccagttcggg acgtttacag ttcactgtaa tactcagccg
     7801 gtcattgcga tgcacggtcg cctcatacct ggcatcgtac aggtatcgct gccccaactc
     7861 catatcctgg agataggcaa taccttttcg tgaagcacag gatgataaca gcagcaccgc
     7921 catgcaactt atgaaaatca ttttttttct catgttgtct tctttgctta ttattaatgg
     7981 ttatataaat attcatattc cttcgttaag gattcctcac acaacagtgc ggccccttca
     8041 tcaggcaggc agtccaattc acctaccgga acagcactaa cggtttccgc cagtgtatca
     8101 tacatcccat tacacaggta agagtgaagg cgtatggccg aacagccggg caacagtgta
     8161 ataaaggcat ccacatcttt ttgaagaacg aaccggttgg catccgcttg ccggagacgt
     8221 acaattccgc ctacaggaaa acaccggttt ttgtaacaag gcgtttttcc actccatggg
     8281 gtaccatatg cgatgctgcg tccggattcc atacgaatcg taggattgtc atcattcagc
     8341 aattcactct ttggaaaaca tttaagccat tgtaccgcat gggtgctctt acccgtaccg
     8401 cttttaccca tgaaaaggta agcttttccc ctccatgcca cggcggaggc atggacagaa
     8461 attcctcccc aaaagagtat tgcctgtgaa tagacgatac gcaaaaggga gcaaaggact
     8521 tccccggcat atgggtcatc ccagcggata tttgccatgg caagagtaaa aaaaggttct
     8581 gcatgcagaa catgtaccgg actaccggca gtataacgca attcaacccg gtatccctcc
     8641 gccatctcaa gcaaacggat atgtcccaga tcactttccg tctcttccaa tacacggata
     8701 attccttttt cggaaagaga actcgaaacc gctacaaaat tgaatattgc cctgccctga
     8761 atatccgtta cgcaacggaa aggacggaac gagggcaaca gccggtctat gtcttgttct
     8821 tcgggtaaat ggagtttgaa aagaaaaccc gccacccgga aatcatattc cctcatcatt
     8881 tgacttgtcc tgtcaataaa ttagtaaatg tccagaaagc ctccttgggt gcatagccga
     8941 aagacaaact cacgttacgc aggaatgagt gtgccgtata caacttgcgc tgccacacag
     9001 cctgtgtccc cggggttcgt tccatccgat actgaccgaa attaccacct tccagcaccc
     9061 tttccagcaa aggacgggat gataccggcc tatccttgta aggcaaagaa gttaccggca
     9121 gtcccaaatg ttccaccagg aacgaatgaa gcaagcggtt ccatccgatt ataccggcct
     9181 tacagcaaat attttttatc tcactggagg ttaccgcgat atgaagccgg tgacaggcac
     9241 gagccatgtc acacaactgg cgaagtccta taccccggcc aatggcatgt ttcattatat
     9301 gggtattgag cagcagcaca taaagcgtgg gcgaaggtat tgttatctca caaccgggtg
     9361 agagccatac gtcatggtag ccaaacaggg tttccaaact attcaggtcc tcatgtaaaa
     9421 agggattata caggtcaagc atacgcggat ggtgttccac ttcgatacta ttccatatat
     9481 agctgacact gtcatctggc tgccagtcta cccgtattcc ccggtttttc actatgcgaa
     9541 tggcaaattc ccgttcattc ttatacggaa aataaaagtc aatatcaccg cattccctta
     9601 acaggggaaa ctcataaaac aatgcggcgc tctggccttt ctgaagaacg ggagtcagcc
     9661 catcgttccg aaacatttca taaagttctg ccagcaccgc attcatccgg tgatttcgct
     9721 gttctatcgc atttatttcg gctacccagc gtaccagcaa cttctccggc ggcaacattt
     9781 catcgggtaa atgacatacc ccacggtaga caagacccgt aacggtctgc cggcgtgcca
     9841 tacgatagat attctcccag ctttcaccgg acaagggaaa aagggacagg ctctccggct
     9901 ctttctccca taaaccggcc cgcaataaaa tgaacagtat ggttacttcc ttattcggat
     9961 acatttccat ttcttttttc aatcaagtgt tctcttacgc ttatccgacc aggccggact
    10021 gtttccattc acacagttgt ttttccacat ccttcagggc atcctcttcc ccaacctcat
    10081 attcattaca caacaatacg gcaagttctt tgggagtgat atcttttcct tccatcaact
    10141 gccagagccg tgcggcggtc tcgttcaggg tgaacacatc ggtcatattc acatttcctg
    10201 aagctgtact tacgatcata tatttattgc cgatttttct taactgtaaa ttgggttgga
    10261 gtttcataag ccctgtcttt gtcataaatt ttaaccgtta gaatttcttt cccaccaata
    10321 tggaaaatac ggtaagaaag atgatttttg tatcaaacca cagggaacgg tggtagagat
    10381 agtccagatc catccgcaac ctttccagca tcttggtcat ggaatccgta taaccattat
    10441 aaagtgtggc ggccgaaaac aatccagggc gtagctgata cagctgttca taatccggat
    10501 ttatggattt gatctggtct acaaaatatt tacgttccgg tcgcggtcct acaaagctca
    10561 tctctccttt gagtacgttc cacaattgtg gcagttcatc caggtgatgt tcacgcagaa
    10621 aacgacccac acgggtaagc cgtttatccc ttttctgaca cagggcgggt ttgccgtccg
    10681 cctccgccag tgtaatcatg gaacggaact tgtacagcgt aaaaatctca ccatgatacc
    10741 ccacacgttc ctggctgaaa atggcctttc catggtcttc acatttaatg gcgatataga
    10801 tcaccagaag taccggggag aaaacggcca atcccactat actggctacc acgtccaaga
    10861 acctttttgt cgtgcgggcg atcggggaca tgatatcccc gctacggctc ctctcggttg
    10921 cactcccctt cactgccttc gatactactt ctactttttc cataaacttc tataaatttc
    10981 taatatattg tctatcattt tttcttttgt gaatgtttcc tgataacgtt ctctggcacc
    11041 tttggccagt ttttggtaca aatcgtcatt acgggtaatc gtcatgatag ctccggccaa
    11101 ctccttggca ctgcagggag ttacgttcag cccggaaaaa ccatgggcat ttacccatga
    11161 tactcccgaa tggggtatgt tggtcgccac cacaggcttg ccgcatgaca tggcttcgat
    11221 ttgtacaata ccgaaagcct ccgttttctg cacgctgctc agacagaata acgtgcaggc
    11281 cccgtagtag gcagaaagtt ccttgtcact aatcctgcca agcaacataa ccttgtcctg
    11341 tacgccccat gtctcaattt cagcctctaa atcatatttc atggctccgc tgccgccaat
    11401 taatatcaca taatcgtcat ccagataatg ggcggattct atcaggtatt tatatccctt
    11461 gtaagcaacc agcctcccta tagagaagat gatcttctta cccgggtacc gtttcctgac
    11521 ctcttctaca gcagccggag ccgggcaaac cggctcaata ccaattggca gacattccat
    11581 cttgtgtcgt acccgtgcaa gacatggcga ctctgccaga taaggcgggg tagtaccgat
    11641 aatcacatct gcacgtgtca acaaccattc ctgcagggga gaataaagtt ttagcaatat
    11701 tttttgtttc tctatgtcag catgccagtg taggataacc ttgcccttat aacctgaaag
    11761 gaacagagcc aggcaggcca tcgggtcggg atggtgcaca tggatgatgt cataatccct
    11821 gcaccttttc cgtaatgaga aaatcatatc gggagaaatc atcgttgcgg caactttcat
    11881 ccaggtacgg caacctatca gccgggaatg agcgttaatg gagaaagtac gggagcttcc
    11941 ttgagacagg gcacatagca tatcacaagg cacaccacgt tccgacagtc cgctcatcag
    12001 gtcatacatc actttttcca cgccgcccat tatcggataa aacttgccga gttggagaat
    12061 cttcaatgct ttcatctttt gaatatttct tcggatatca tgtcttcgga ttgtaataac
    12121 ggatatttcc tttaatgaat aaaaggaatt aaaggtacta tgcacagact aaatactgta
    12181 gattcaaatc aaatcatata atagatatgg ttgatcatca tttataaatg tcagcaat
//
