LOCUS       c00049_gnlPro..        13984 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DCPIMBAF_49.
ACCESSION   c00049_gnlPro..
VERSION     c00049_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:13:07
            Original ID  :: gnl|Prokka|DCPIMBAF_49
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13984
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13984
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2238:5211]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2239..5211
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13984
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13984
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             3..320
                     /locus_tag="ctg49_1"
                     /transl_table=11
                     /translation="FKDVTFKIDGLPLKSYEFKDSKNELMIQISDCIIGLICRFYKFLD
                     EYDGNICTLDARLNERQKTNLSILCKILKKTIDYNEKLIHMVVPMKEARNYNSIVRKYA
                     K"
     CDS             complement(443..1672)
                     /locus_tag="ctg49_2"
                     /transl_table=11
                     /translation="MERTTFCLLFYIRRTKLNRNGEAPIMMRITVNGVRVDASVKKTIL
                     PEFWSVAKGKALEKKREYKELNLYLDSIRLRIMKIQRELEIEGVAVSAGSVLDRFLGKD
                     APVQRTLFEVFREHNDKCARLSGTDMAPATVQRYETSLKHTQDFVWETYHKKDILLDEV
                     SRQFVEDYEFWLKTEKKCCHNTATKYLKNFKKIIRIALAKGWMKNDPFLEIRFSLDKVE
                     PDFLEDSEIRKLISKEIDIPRLSQVRDIFVFCCFTGLAFSDIHDLRKEHIVEDSNGVRW
                     IRKGRQKTKIMCNIPLMEIPLKILEKYSTNEYCKKHGVLFPVLCNQKMNAYLKELADIC
                     GIKKTLTTHVARHTFATFALANGVSIESVAKMLGHTNVQMTRHYARVLDRTVIREMSQI
                     KMDFHFSVQK"
     CDS             2239..4467
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_3"
                     /sec_met_domain="Gly_radical (E-value: 7.3e-47, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTDARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             4483..5211
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_4"
                     /sec_met_domain="Radical_SAM (E-value: 6.4e-30, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(5239..5682)
                     /locus_tag="ctg49_5"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRADRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDEDGKAADTRTSRQKESLHRLVRELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVKAETW"
     CDS             complement(5669..5860)
                     /locus_tag="ctg49_6"
                     /transl_table=11
                     /translation="MITLILDQMKEIVTKILDVIMFLVPFFGKRKRNRIVREVRFNATH
                     KEVCNVKTTEREKDDEKD"
     CDS             complement(5857..6360)
                     /locus_tag="ctg49_7"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             6554..6784
                     /locus_tag="ctg49_8"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNPPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             6872..8989
                     /locus_tag="ctg49_9"
                     /transl_table=11
                     /translation="MDHFTIFQDFYRVIAEMTEEEIVSAISNGTYRETVEDVRRIFAEQ
                     GEKAANEKKIELPEITFSANYRGGRSNATLVKYLGYIVVDIDHQTQEALARILALAKKC
                     AHTRIAFISPKGMGLKIVVRVCRTDGTLPETIQEIEDFHHAAYHKIASFYAQLCGVEVD
                     TSGQDVSRTCLFSYDPDIYFNPDATAVIVEQPPMFFKSQKKKRASGKKKKTTAPDNNPL
                     TEQVALNYHSSHTSLMVTLNYYHNKSEKYVTGNRNNYLHCLACMYNRYGVPQEEAAAFI
                     KSQFTDLPADEMDALIGSAYGHNEEFDTRKLNSTQKRMLQIEQHIKENYDTRYNEVLHI
                     MEYRRRKTDTEQPEPFHILDEMMENSIWMEMNELGYSCTVKTIQNLIYSDFSITYHPIR
                     EYLDSLPEWDGTDYIGILANSVHTSHQKFWVECLERYLVGMCAAATQDDVVNHTVLLLC
                     SEIQNIGKTTFINNLLPPELRAYLSTGLINPSNKDDLAKIAQAMLINLDEFEGMSGREL
                     NIFKDLVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVDSME
                     FIKINYAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPE
                     RFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIID
                     TEQVKSNRLYE"
     CDS             complement(9131..9220)
                     /locus_tag="ctg49_10"
                     /transl_table=11
                     /translation="MVGNLKKLTVFFKFPTVFLRKKEEEKGKR"
     CDS             complement(9238..9543)
                     /locus_tag="ctg49_11"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTVTRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCRIEFSMSL"
     CDS             complement(9524..9856)
                     /locus_tag="ctg49_12"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFDRLDTGTQDKILYVLMLLQTQDRIPLKFM
                     KLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIEKAKILRKEY
                     YGSKNK"
     CDS             complement(9913..10158)
                     /locus_tag="ctg49_13"
                     /transl_table=11
                     /translation="MSHLTPVTIEYRGNPKQYVSVVLDAINRGRLTYDGIANCEQTFRA
                     LASVVDVISPKNGKTLSVETLVSYEKKKRAGEFEEK"
     CDS             complement(10167..10301)
                     /locus_tag="ctg49_14"
                     /transl_table=11
                     /translation="MENSCNDELFCSLKNELREVTAQINVHSEKLMELLDQKKESSVN"
     CDS             complement(10421..11692)
                     /locus_tag="ctg49_15"
                     /transl_table=11
                     /translation="MKRFILLTILCCLVLSISAQIARDEIFEDIHRSAANHYAYPDPHF
                     TMTAPPKGYKPFYLSHYARHGSRYRVNPDDYTKPLAILREAEKDGVLTDLGKKALWLVD
                     SLARGAENRYGDLTPLGARQHRGIARRMYNNFPEVFQGAAEVDARSTTVIRCILSMTAE
                     CLQLQSLNPELRIKDEATSYDMYYMNYGNEYFKKKRQEDEVIAVKAAFRKEHLHPERLM
                     KSLFNNDNYVKWKVDAGKLMSYLFELAAITQSHDTDLDLYSLFTKEECYDLWLISNLNW
                     YIDYGPSPLTQGKMPYVEANLLENILNTADTCVVKKENSATLRFGHETCLLPLACLLEL
                     GDCAYQTTDINKLSDIWRNYRIFPKACNIQFVFYRKKGNDNILVKILLNEQEMKLPLAS
                     ELVPYYHWEEVERYYRNKLATFVH"
     CDS             complement(11729..13000)
                     /locus_tag="ctg49_16"
                     /transl_table=11
                     /translation="MDIKKIVNFIFLLVFSCIIKAQMTIPPFPKWEKGYLDIHHINTGR
                     GNCAFLIFPDGTTMMIDAGDFDGKEYAAKYAPMHAAPIFPDSSYTPGSSIINYVTNLLG
                     KDVVIDYFLLTHFHSDHYGDVQKATGTSKNGYRITGLTEVGDVIPIKMYVDRDYPDYQF
                     PVDLRSKNDGVDLPTFLNLLEFLNYQEKHNGLKVEKFDIGSNTQFVLKKEPKSYPGFEV
                     RNIKSNNRLWTGEGKKTTILFTKEELMAKNGKYSENQMSTAIVVKYGAFKYYAGGDNSG
                     LVDQDHAEWYDIETPMAPIIGKVSAVSLNHHSNRDATNRNFLEVLDPKVVVAQSWSTDH
                     PGAEVGQRLLSKNIGTQPRDVFMTYYDDETGVAIGPWFARSLKAKQGHIVIRVYPDGEY
                     EVYVLDARKTDLVISNRFGPYSSE"
     CDS             complement(13037..13888)
                     /locus_tag="ctg49_17"
                     /transl_table=11
                     /translation="MKYLNILLIILPFIFSCSSDTPENDKEKIPPIIDTSIRVGTFNVD
                     VGQTATAEEIALSLKSFYLDILSLEECPILIDKNSGVEEFYSIIGKALGMEYFYIGDIS
                     SGNHWIEWGKDKTGKYAGKYKVILSKTPILQSKEFALEGKGWTHSSTIRIETKIKNKEL
                     TFYSLHIPGSAGVVEGSVMKNLVDVVLMKDTSKRIIVMGDFNDLPETNAMQYIFNSGFK
                     SVWDDVEDAEQYIDKYKYGQIDNILINKNSGMKAEIAYSIFKKDISLSDHPFLWSKIII
                     GE"
ORIGIN
        1 atttcaagga tgtgacgttc aaaatagatg gtttaccctt aaaatcatat gaatttaaag
       61 attctaaaaa cgaactaatg atacaaattt cagattgtat tatcggatta atttgtcggt
      121 tctataaatt tcttgatgag tacgatggaa atatttgtac ccttgatgca cgactcaacg
      181 aacgacaaaa aacaaatctg agtattttgt gcaaaatcct caaaaagact atagattata
      241 atgaaaaatt aattcatatg gtcgtaccta tgaaagaagc ccgtaattat aactcaatag
      301 tccgaaaata tgctaaataa gtagagatat ttagtaaatg tcactatttt tatataaaga
      361 tgaagagtta ctctattttt caattagcct tactcttcat cttttatatt ttcatacttt
      421 gtatacaaga atacgaatat atttattttt gaacagaaaa atgaaaatcc atttttattt
      481 gtgacatttc acgtatcacc gtacggtcca gcacacgtgc ataatgacgg gtcatctgga
      541 cattggtatg gcctaacatc ttagcaacgc tctctatcga gacaccattg gccagagcaa
      601 atgtggcaaa agtatgcctc gcaacgtggg tggtcaatgt ttttttaata ccacaaatat
      661 cagccagttc cttgagatat gcattcattt tttgattaca aagcactgga aaaagcacac
      721 catgtttctt acaatattca ttggtggaat acttttccaa aatcttcaat ggtatttcca
      781 tcaatggaat attacacatg attttggtct tctgtcttcc cttgcgtatc cacctaaccc
      841 cgttcgaatc ttccacgata tgttcctttc tcaaatcatg aatatccgaa aaagccaaac
      901 cggtgaaaca acagaacaca aaaatatccc gtacctgact taaccgtgga atatcaattt
      961 ccttcgatat cagcttccgg atttctgaat cttccaaaaa gtccggttcc accttatcca
     1021 atgagaatct aatttctaaa aacggatcat tcttcatcca tcccttagcc aaagcaatac
     1081 ggatgatctt cttaaaattc ttcaaatatt tggtagctgt gttatgacaa cactttttct
     1141 ctgtcttaag ccaaaactcg taatcctcaa caaactggcg ggaaacttca tccaaaagaa
     1201 tatctttctt atgatatgtc tcccagacaa aatcctgagt atgcttcaag gatgtctcat
     1261 aacgctgcac ggttgcaggc gccatatccg taccagacaa tcgggcgcat ttatcattat
     1321 gttcacggaa aacctcaaac agggtacgct gtacgggagc gtccttaccc aaaaaacgat
     1381 ccaggacact gccggcagaa actgctacac cttctatttc caattcacgc tgaattttca
     1441 ttatcctcaa acggatagaa tcaagataca gattcagctc cttgtactca cgcttctttt
     1501 ccagggcctt cccttttgcc acactccaaa attccggaag aattgttttc ttcactgaag
     1561 catcaacccg aactccattc actgtaattc tcatcattat cggagcctca ccgttccgat
     1621 tcaatttcgt cctacgaatg tagaacaata gacaaaatgt tgttctttcc atcttacttg
     1681 ttttttaatc acaaaactaa aattccaaga gcaacaagtc aagatgcaaa acactgataa
     1741 acaatgaatt atttacttaa taggtgtacc tgacattgaa ggagatcagg tacaccgaat
     1801 agtacaccga aagaatgctt tgatatgctt atttttgcca tgcaccaaaa acaaaaaatc
     1861 cctgtaaagt attaatttac agggattttc tttgttttgc aattctttcc agcggagaga
     1921 cagggattcg aaccccgggt acctcgcagt acaacggttt tcaagaccgc cgcaatcgac
     1981 cactctgcca cctctccaaa acttctttat cagaagtgct tttcgttaaa agcggtgcaa
     2041 aggtacgaat atattttaaa cttacaagag ttttcacaaa aaaaaatcac gaacatcatt
     2101 tccaaagaat agcaatatct aggtatttta tgttgaaaag cataaaatag agcatattta
     2161 tgctgattat atgaaaaaac gttgtaactt tgtgcgctct aaagaaaagg ataactacaa
     2221 cctctaattt tatcatttat ggaattaaat aagatcttta aagacggtct ttggagcaca
     2281 gaaatcaacg taagagattt cgttagtcac aacatcactc cgtattatgg agatgcttct
     2341 ttcctcgaag gacctaccga acgcacaaaa gctgtatgga accgctgcct cgaagcactg
     2401 gcagaagaaa gagccaataa cggcgtacgc tcactggata atgtcaccgt ctcaaccatc
     2461 acttctcata aagccggata tatcgacaaa gaaaacgaac tgatcgtcgg tctgcaaaca
     2521 gacgaacttc tgaaacgtgc aatcaaacct ttcggaggta tcaacgtggt gagcaaagcc
     2581 tgccacgaaa acggcgtgga agtggacgac cgtgtaaaag atatattcac tcactaccgc
     2641 aagacacaca atgacggagt atttgacgta tataccgaag aaatccgttc gttccgttct
     2701 ctgggattcc tcaccggact tcctgacaac tatgcccgcg gacgtatcat cggcgactac
     2761 cgccgtatgg ctctctatgg tatcgaccga ctgattgagg caaaaaaaga agacttgcgt
     2821 aaccttaccg gtccgatgac cgatgcccgc atccgcctgc gcgaagaagt ggcagagcaa
     2881 atcaaggcat tgaaggacat gaaggtaatg ggcgaatact acggactcga cttgagccgt
     2941 cctgcctaca ccgcacaaga agcagtacaa tgggtataca tggcttacct cgctgccgta
     3001 aaagaacaag acggtgctgc catgtcactg ggtaacgtct cttcgttcct cgacatttat
     3061 atggaatatg aattgagcaa aggaaccatc acagaatctt tcgcacagga gctgatcgac
     3121 cagtttgtca tcaaactgcg tatggtgcgt cacctgcgta tgcaatctta caacgacatc
     3181 tttgccggcg acccgacatg ggtaaccgaa tccctgggcg gacgcctcaa cgacggacgt
     3241 accaaggtga caaagacttc tttccgcttt ctgcaaacac tctacaacct cggcccttca
     3301 ccggaaccga acctgactgt attgtggagc ccggaactgc cggaaggatt caaagaattc
     3361 tgcgcaaaag tatctatcga cacttcttcc atccaatatg aaaacgacga cctgatgcgt
     3421 gaagtgcgcc agtctgacga ttacggaatc gcatgctgcg tatcttatca ggaaatcgga
     3481 aaacaaatcc aattcttcgg cgcacgttgc aacctggcaa aagccctgtt acttgccatc
     3541 aacggcggac gttgcgaaaa caccggtacg gtaatggtga aaaatatccc cgtactaacc
     3601 agcgacacac tgaacttcga agaagtaatg agcaactaca agaaggtatt gacagaaatc
     3661 gcccgtgttt acaacgaagc gatgaacatc atccattata tgcatgataa gtattactac
     3721 gaaaaagccc aaatggctct tgtagatacc aacccacgca tcaaccttgc ttacggtgta
     3781 gccggacttt ctatcgccct cgattcactg tcggccatca aatatgctaa agtaaccgca
     3841 cgccgcaacg acatcggtct gacagaaggt ttcgatattc aaggcgaatt cccttgcttc
     3901 ggtaatgaca acgacaaggt agaccacctg ggtgttgacc tggtctattt cttcagcgaa
     3961 gaattgaaga aacttccggt ttacaaaaat gcccgtccta ctttatcttt gctcaccatc
     4021 acttccaacg tgatgtatgg caagaagaca ggtgctactc ccgacggacg cgccaaaggt
     4081 gtcgcttttg ctccgggagc caaccctatg cacggacgtg acaagaacgg tgccatcgcc
     4141 tctttgagtt ccgtagcgaa attacgttac cgcgactcac aggacggtat cagcaacact
     4201 ttctccatcg tccccaaatc actgggagct actgaagagg atcgcgtaga aaatctggtg
     4261 acaatgatgg atggctattt caccaaaggc gctcaccacc tgaacgtgaa cgtactgaac
     4321 cgtgaaatgc tttacgatgc catggaacat ccggaaaaat atccgcaact caccatccgt
     4381 gtttccggtt atgccgtaaa cttcgtgaag ttgagccgcg aacatcaatt ggaagttatc
     4441 agccgtagct tccacgaacg tatgtaatca gatctactca atatgacgat aaacgtacat
     4501 tcatacgaaa gtatgggaac attcgacggg ccgggcttac ggctcgtcgt ttttcttcaa
     4561 ggatgcaatt tccgctgcct gtattgcgcc aaccctgaca caatagccgg gaaaggaggc
     4621 acacctactc caccggaaga aatcgtccgc atggctatga gccaacgtcc ttttttcggg
     4681 aaacgcggag gagtcacttt ctccggagga gaacctacgt ttcaggccaa agcactagtc
     4741 cctttagtgc gtgaactgaa agaaaaggga atacatgtat gcatagacag caacggcggt
     4801 atctggaacg aagaagttga agaacttttc aaactgacgg atcttgtatt gctggatatt
     4861 aaagagttca atccggcacg ccatcaagca ctgaccggaa gaagtaacga gcaaaccatc
     4921 cgcacggcag catggctgga agaaaacgag aaacctttct ggctgcgtta tgtattagtg
     4981 cccggataca gcgatttcga ggaagacatc cgccgtttag gagaagctct gggaaaatat
     5041 aagatggtgc aacgagtgga aatcctgcct tatcatacat taggcgtaca taagtatgaa
     5101 gcgatggagc aggaatacaa gctgaaagac gtaaaagaaa atacccccga acaacttgaa
     5161 aaagctgcgg aggtatttaa agagtatttc actactgtgg tggtcaatta accaccacag
     5221 taataaatag gataaaaatc accatgtctc tgctttcacc tcgaaacagg gacactcttt
     5281 gatccgctcc caagggtcaa caattccatt ataattggtg tcaggactca aatcacggtg
     5341 tcccaccact tttgcatccg gataacgctg caacagttcg cgcaccaggc gatgcaaaga
     5401 ttctttctgg cgggaagtac gcgtatccgc tgcctttccg tcctcatcca gtccgccttc
     5461 ataacacacc cctaaactaa tcgcattaaa accgcgtgca tgagcaccca ccgtatcttc
     5521 atccctcatc ggctctatct gtcccgactt gcgaatgtag taatgatacc cccaacacga
     5581 aaagccccga aagcgatggg cagtgtccac atccttcgcc gtgaagtcgc gatcagcacg
     5641 ggtagcagag cagtgaatca caatcagact aatctttctc atcgtccttc tccctttccg
     5701 tcgttttcac attacacact tccttatggg tagcattgaa gcgcacctct ctcacaattc
     5761 tgttccgctt tctttttccg aagaaaggca caaggaacat aattacatcc aaaatcttag
     5821 ttacaatttc tttcatttga tccaatatta aagttatcat gctgccggat ccggagcttc
     5881 tccgcttcca ccaccgtctg aaccaccacc ggaacctttg tcatcgtctt ctccttcatt
     5941 gccgctaccg cccgtttgag ccaccgcacg cgtcgttacc tgctggtagc taagaatctt
     6001 cgtgatgtcc gccaacgtct ttccgggacg gaaaataata tgggcagccg taatcagcga
     6061 acttgaaaac tccttgaccg acacagctcc ttcactgttc aacccgatct gcaaactgcc
     6121 caaatcaccc agccggacta ttcttcccgc tttcaacgca cgcttcgcct cataaagaat
     6181 acccgaaatg gcggcacgca catctgtctc cgtacaggta gaccgactgg tgattccttc
     6241 gcacaactct tcaaaatcca actctcccga agcctgtgcc tgcgcgtaat actttgccga
     6301 ctcatccttt ttggcaggat tcttgcgcgg cactactgaa taagttactg tcattgccat
     6361 aataaaataa ttttaagatt tcacacattt cgaacgcgtt ccttatttgt taacgacata
     6421 aagataacac attttccatc ctccggattc cccaacgaag tttcctgata ctctatgaat
     6481 aataatgacg ttattctttt aataaaccat taattttcag taactttata gcataaacca
     6541 aacattattc atcatgtatt atccggacca gccgtttcat atccgcactt ataaaaagtc
     6601 ggaactagct catctttaca accccaacgt atgccttaaa gtagccttac aaatactacg
     6661 tcgttggatt gtctacaacc ctccgctcct gcaagaactc gaacaagaag gctatcgtgc
     6721 ccgcaaccgc cttctctctc cccggcaagt ggcaacgatc atacgctatt tgggagaacc
     6781 ctaggaactt aatcaaaaaa acgaaaagtt ccattctatt attttacaaa caaatttctt
     6841 tgcaaccgca aattaaaaag aacaaaccaa catggatcat tttaccatct ttcaagactt
     6901 ttaccgcgtt atagccgaaa tgacagaaga agaaatcgta tcggccatca gcaacggcac
     6961 ataccgggaa acggtggagg acgtgcgccg aatcttcgcg gaacaaggcg agaaagcagc
     7021 caacgaaaag aaaatagaac taccagaaat caccttttca gccaactacc ggggaggacg
     7081 ttcaaacgca actctcgtca agtatctggg atacatcgtg gtagacatcg accatcagac
     7141 acaggaagca ttggcacgca tcctcgcact ggcaaaaaag tgtgcccaca cccgcatcgc
     7201 tttcatcagc cccaaaggaa tgggactgaa aatcgtggta cgtgtatgcc ggacagacgg
     7261 gacattgccc gaaacaattc aggaaattga agatttccat catgctgctt atcacaaaat
     7321 cgcttccttt tatgcccagc tctgcggagt tgaggtcgac acttccgggc aggatgttag
     7381 ccgcacttgc ctgttctctt acgatccgga tatttatttc aatcccgatg ccacagctgt
     7441 catcgtggaa cagccaccga tgttcttcaa gtctcaaaag aagaaaaggg catccggcaa
     7501 aaagaaaaag acgacagcac cagacaacaa tcccctcacc gaacaagtgg ccctcaacta
     7561 ccattcctcg cacacttcct taatggtgac tctgaactat tatcacaata aatccgaaaa
     7621 gtacgtcacc ggcaaccgga acaactacct gcattgcctg gcttgtatgt acaatcgcta
     7681 cggcgtcccc caggaagagg cggcagcttt tatcaagagc cagttcaccg atcttcccgc
     7741 ggatgaaatg gacgcactga tcgggagtgc ttacggacac aacgaggaat tcgacacccg
     7801 caagctgaat agtacgcaga agcgaatgtt acagattgag caacatatca aagaaaatta
     7861 cgatacacgc tacaacgaag tgcttcatat catggaatat cgcagaagga aaacggacac
     7921 ggagcaaccg gaacctttcc atattctcga cgaaatgatg gaaaacagca tttggatgga
     7981 gatgaacgaa ctgggctatt cgtgcaccgt caagacgatt cagaatctga tctactccga
     8041 cttcagcatc acctaccatc ctattcgcga gtatttagac tcgctgcctg aatgggacgg
     8101 aacggattat atcggtatcc ttgccaacag cgtgcatact agtcaccaga aattttgggt
     8161 agaatgtctg gaacgttatc tggtgggaat gtgcgctgcc gccacacaag atgatgtggt
     8221 gaaccacact gttttgttgc tttgcagcga aatacagaac atcggaaaga ctacgtttat
     8281 caacaacctg ctgccgcccg aattgcgcgc ctatctttct accggtctta tcaacccgag
     8341 caacaaagat gatctggcta aaatagcgca ggcgatgctt atcaatctgg atgagtttga
     8401 agggatgagc ggacgggaac tgaatatctt caaggattta gtcacccgca aagtaatcag
     8461 catccgcctg ccatacgcgc ggcgttcgca gaactttcct catacggctt cttttgccgg
     8521 cacatgcaat taccaggaag tgcttcacga caccacaggt aaccgccgtt ttctctgctt
     8581 tcatgtcgac tcgatggagt ttatcaaaat aaactacgcg cagttgtatg cacaaatcaa
     8641 gtatctactc aacaagccgg ggtatcagta ttggttcacc cagtcggaaa actcacggat
     8701 tgaagagaac aacgaggatt tcattttcca ctcaccggaa gaagaactgg tgttgacaca
     8761 tatccgcaaa ccggaacgtt tcgaaaaggt gcattatctg acggtcactg aaattgcgga
     8821 attgattcgc gaacggacgg ggtatcaata ttctcacgga accaaagccc aactaggaaa
     8881 agtgatgtcc aaacacggct tcgaatttca taagggaaaa aacgggagaa gatacactgt
     8941 attcattatt gatacggaac aggtgaaatc aaacaggcta tatgaataag atttcatctc
     9001 cttcgcacgc aaaaaggtga gggttggtga gggtactttt gcaacttttc atttttatat
     9061 ttcttatttc tattcttcta ttttcttcta aaaaaaaata cgaatgttag aaatttaccc
     9121 tcacctaccc tcaccttttt cctttttctt cctctttctt cctcaaaaaa acggtgggaa
     9181 atttgaaaaa gacagttaac tttttcaaat ttcccaccat gtttttttaa tcgcttctta
     9241 taaagacatc gaaaattcga tcctacaacc taacgcattc atgatgcgat agaaggtaga
     9301 aaccttaggc tctgtctgac cactttccac tcttgaaata taagaacggt cggaaccgat
     9361 acgtcgggct aactctgctt gagtaatctt agcctttttc cttgcgtctt cgataatttg
     9421 cccggtgtag aaagcatacg ctttttcttc tgcttccgca cgagtaacag ttccttcctt
     9481 accaaaacgc tcatctatta atgcgctgac gttaaagaat tcctcatttg tttttgcttc
     9541 cataatactc ctttcttaat atctttgctt tttcaatttc tttctttggg gtcttttctg
     9601 ttttcttttg gaatccgtta aagagtatca caatacgtcc ttcatcgaaa caaaagaata
     9661 ttctatatat attactctgg tactcaatac gaagttcata aagtccttct tctatcaact
     9721 tcataaactt caaaggtatt ctgtcctgcg tttgcaatag cattaacaca tataatatct
     9781 tatcttgggt gccagtatcc agacgatcaa agaactcttt gaaatatcct ttatatgcta
     9841 ttatttctct tttcatactg caaatatatg aattgttgtt caactataca acattcgtct
     9901 ttttatttta tattattttt cctcaaattc tccggcacgc tttttcttct cataagacac
     9961 cagcgtctct acactaagcg ttttcccatt cttagggctt atcacatcta caacgcttgc
    10021 taacgcacga aaagtctgtt cgcaatttgc tattccgtca tacgtcaacc taccccgatt
    10081 gatggcatcg agcacaacag agacatattg cttcggattt ccccgatact caatggtgac
    10141 aggcgtgaga tgcgacatct ctcgagtcag ttgactgacg attctttttt ttggtcgagc
    10201 agctccatta atttttcact atgcacattg atttgtgcgg ttacttcacg aagttcattt
    10261 ttcaatgaac aaaacaattc atcattacat gaattttcca taaaactttt catttaattg
    10321 attataaaaa agccattcca gaaagataag caatcattac ttacttcccg gaatggtgac
    10381 taacattttt aagaccagtt tttgtatatt actgtttctt tcaatggaca aaagtagcca
    10441 atttattcct ataatatctt tccacctctt cccaatgata atagggtact agctcacttg
    10501 caagcggaag tttcatttct tgttcattga gtaaaatttt caccaagata ttatcatttc
    10561 ctttcttacg gtaaaaaacg aactgaatat tacaagcttt tggaaagata cgatagttac
    10621 gccatatatc tgacaattta tttatatcag tagtctgata tgcacaatca cctaattcca
    10681 ataaacaagc caaaggaagt agacaagtct cgtgcccgaa gcgcagggta gcactattct
    10741 cttttttcac gacgcaagta tctgcagtat tcagtatatt ctcaagcagg tttgcttcca
    10801 cataaggcat cttaccttga gtgagcggag acggcccgta gtcaatatac caattcagat
    10861 tgctgattag ccataaatca taacactctt ctttggtaaa aagagaataa agatcaaggt
    10921 ccgtgtcgtg actttgcgta atggctgcca gttcaaacaa ataactcatc aacttgccag
    10981 catccacttt ccactttaca taattatcgt tattaaaaag agacttcatc aaacgttcgg
    11041 gatggagatg ctctttccga aaagctgcct ttacagcaat cacttcatct tcctgacgct
    11101 tctttttgaa gtattcattt ccataattca tataatacat atcataagaa gtagcctcat
    11161 ccttgattct caactccgga ttcagagatt gcaattgcaa gcactcagcc gtcatagaga
    11221 gtatacagcg gataacggtt gtagaacgtg catccacctc tgccgctccc tgaaacactt
    11281 caggaaagtt attgtacatt cttcgggcaa ttcccctgtg ttgacgggca cctaatggag
    11341 tcaaatcacc atatctattt tctgctccgc gcgcaaggct gtctacaagc cagagggcct
    11401 tcttgcctaa atctgtaagt actccgtctt tctctgcttc gcgaagaatt gccaacggct
    11461 tcgtataatc atcaggattc actctataac gggaaccgtg acgagcataa tggcttaggt
    11521 agaacggttt ataccccttg ggtggggcag tcattgtgaa atggggatca ggataggcat
    11581 aatggttggc tgccgagcga tgtatgtctt caaatatttc atctcttgct atctgtgcac
    11641 ttatactaag cacaaggcaa caaaggattg tcaacaaaat aaaacgtttc atactttctt
    11701 tttttaataa gtttaagata ccacagaatt attcactaga gtaaggacca aacctgttcg
    11761 atataaccaa gtctgttttc cgggcatcca gcacatatac ttcatattcc ccgtctggat
    11821 atactcttat cacaatgtgc ccctgttttg ctttcaagct acgggcaaac caaggaccaa
    11881 tagctacccc cgtttcatca tcatagtaag tcataaaaac atccctaggc tgcgttccga
    11941 tattctttga taacaaccgt tgccccactt ccgctcccgg atgatcggta ctccatgatt
    12001 gagccactac tactttagga tcgagcactt cgagaaagtt ccggttagtg gcatcccgat
    12061 tgctatgatg attgagcgac actgccgaca cctttcctat tatgggtgcc ataggagttt
    12121 ctatatcata ccattccgca tggtcttggt ctaccaaacc agaattatcc cctcccgcat
    12181 aatacttgaa tgcgccatat ttcaccacaa tagccgtcga catttggttt tcactatact
    12241 tgccattttt tgccatcaat tcttccttgg taaacagaat agtcgttttt ttaccttccc
    12301 ctgtccacaa ccgattattc gattttatat tcctgacttc aaaccccgga taagatttcg
    12361 gttctttctt taatacaaat tgcgtattag agcctatgtc gaacttttcg actttcaatc
    12421 cgttgtgttt ttcctgatag ttgaggaact ccaataggtt caagaaagta ggcaaatcta
    12481 ctccatcatt ctttgatcgt aaatccacgg ggaattggta gtcaggataa tccctatcaa
    12541 catacatttt gataggaatc acatctccga cttccgtcag ccccgtaata cgatatccgt
    12601 ttttggaagt tccagtggcc ttctgaacat caccataatg atcggaatga aaatgggtca
    12661 gaagaaaata gtcaatcact acatcctttc ccaatagatt tgtcacataa ttaatgatag
    12721 acgaaccggg cgtataacta ctatccggaa atatcggagc tgcatgcatc ggtgcatact
    12781 tagcggcata ttccttgcca tcaaaatcac cggcatcaat catcatggtc gttccgtcag
    12841 gaaaaatcag aaaagcgcaa ttcccccgcc cggtattgat gtgatgaata tcaaggtatc
    12901 ctttctccca tttagggaaa ggcggtattg tcatttgagc cttgattata caactaaaaa
    12961 cgagtaaaaa tatgaaatta actattttct ttatatccat cgttctatca atctgtttat
    13021 aaattactac tgtactttat tctccaataa ttattttact ccatagaaat ggatgatctg
    13081 aaagactaat gtctttttta aaaatgctat atgcgatttc cgctttcata ccagaattct
    13141 tattgattaa tatattatca atctgcccat atttgtattt atcaatatat tgttcagcat
    13201 cttccacatc atcccataca ctcttaaagc ctgaattaaa gatgtattgc atggcattag
    13261 tttccggcaa atcattgaag tcgcccatga ctatgattct tttactagta tctttcatca
    13321 aaacaacatc tactaaattc ttcatgacag aaccttcaac tactcctgcg ctacccggaa
    13381 tatgcagact ataaaaggtt agttccttat ttttaatctt ggtttcaatc cgaatagtcg
    13441 atgaatgtgt ccaacctttt ccctccaaag caaattcttt tgactgcaat ataggagttt
    13501 tactcaatat tactttgtat tttcctgcat attttccagt tttatccttt ccccattcaa
    13561 tccaatgatt tccggaggat atatcaccga tataaaaata ttccattccc aaagctttac
    13621 ctattattga ataaaactct tcaactccgg aattcttatc aatcaaaatg ggacattctt
    13681 ccaatgaaag aatatctaaa taaaaagact ttagactcaa tgctatttct tccgctgtcg
    13741 ccgtttgccc tacatccacg ttaaaagttc cgacacgaat agaagtatct attatagggg
    13801 ggattttttc cttatcattc tccggagtat cactactgca tgagaatata aaaggcaata
    13861 ttataagcaa aatattcaga tatttcatag ctattaatta tttagaatca gaccctctat
    13921 catttaagat aacgtgagtt cgatgaatta taactatttg taaatttggt gattagcgaa
    13981 aatt
//
