## Fri May 2 02:04:19 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_013425775.1/GCA_013425775.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_013425775.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_013425775.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs NAGPHGKN_00002 568703.LGG_01884 5.24e-113 325.0 29PA5@1|root,30A8A@2|Bacteria,1U6BM@1239|Firmicutes,4IG39@91061|Bacilli,3F7J0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00003 568703.LGG_01883 2.78e-118 337.0 29Q3J@1|root,30B27@2|Bacteria,1U7EP@1239|Firmicutes,4IHAJ@91061|Bacilli,3F9HJ@33958|Lactobacillaceae 91061|Bacilli S MucBP domain - - - - - - - - - - - - MucBP NAGPHGKN_00004 568703.LGG_01882 2.62e-152 427.0 COG2910@1|root,COG2910@2|Bacteria,1TZ3T@1239|Firmicutes,4HVUN@91061|Bacilli,3F5K7@33958|Lactobacillaceae 91061|Bacilli S NAD(P)H-binding - - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 NAGPHGKN_00007 568703.LGG_01881 1.12e-115 331.0 COG0703@1|root,COG0703@2|Bacteria,1V1Z4@1239|Firmicutes,4HKRE@91061|Bacilli,3F91J@33958|Lactobacillaceae 91061|Bacilli E AAA domain - - - - - - - - - - - - AAA_18 NAGPHGKN_00008 568703.LGG_01880 1.42e-169 474.0 COG2755@1|root,COG2755@2|Bacteria,1UI5G@1239|Firmicutes,4ISEF@91061|Bacilli,3F6R2@33958|Lactobacillaceae 91061|Bacilli E lipolytic protein G-D-S-L family - - - - - - - - - - - - - NAGPHGKN_00009 568703.LGG_01879 3.58e-128 365.0 COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,4HPFS@91061|Bacilli,3F729@33958|Lactobacillaceae 91061|Bacilli P FeoA feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA NAGPHGKN_00010 568703.LGG_01878 9.93e-175 505.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,3F553@33958|Lactobacillaceae 91061|Bacilli P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - iSB619.SA_RS13395 FeoB_C,FeoB_N,Gate NAGPHGKN_00011 568703.LGG_01878 8.39e-314 866.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,3F553@33958|Lactobacillaceae 91061|Bacilli P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - iSB619.SA_RS13395 FeoB_C,FeoB_N,Gate NAGPHGKN_00012 568703.LGG_01877 4.52e-34 116.0 2BP56@1|root,32HW1@2|Bacteria,1U802@1239|Firmicutes,4IHXF@91061|Bacilli,3FADE@33958|Lactobacillaceae 91061|Bacilli S Virus attachment protein p12 family - - - - - - - - - - - - P12 NAGPHGKN_00013 568703.LGG_01876 0.0 1088.0 COG1274@1|root,COG1274@2|Bacteria,1UIM9@1239|Firmicutes,4HED4@91061|Bacilli,3FBXE@33958|Lactobacillaceae 91061|Bacilli C Phosphoenolpyruvate carboxykinase pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP NAGPHGKN_00014 568703.LGG_01875 3.89e-75 224.0 29MVS@1|root,30B68@2|Bacteria,1U7M8@1239|Firmicutes,4IHID@91061|Bacilli,3F9WC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00015 568703.LGG_01874 1.17e-295 804.0 COG3669@1|root,COG3669@2|Bacteria,1UYIM@1239|Firmicutes,4HJ46@91061|Bacilli,3F5S7@33958|Lactobacillaceae 91061|Bacilli G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos NAGPHGKN_00016 568703.LGG_01872 0.0 898.0 COG2211@1|root,COG2211@2|Bacteria,1TS1S@1239|Firmicutes 1239|Firmicutes G MFS/sugar transport protein - - - - - - - - - - - - MFS_2 NAGPHGKN_00017 568703.LGG_01871 1.39e-96 281.0 29PS8@1|root,30AQG@2|Bacteria,1U6ZG@1239|Firmicutes,4IGTR@91061|Bacilli,3F8RT@33958|Lactobacillaceae 91061|Bacilli S function, without similarity to other proteins - - - - - - - - - - - - - NAGPHGKN_00018 568703.LGG_01870 2.43e-87 256.0 29P63@1|root,30A48@2|Bacteria,1U666@1239|Firmicutes,4IFWC@91061|Bacilli,3F75Z@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00019 568703.LGG_01869 0.0 1446.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F44P@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD NAGPHGKN_00020 568703.LGG_01868 0.0 933.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,3F4WU@33958|Lactobacillaceae 91061|Bacilli U amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 NAGPHGKN_00021 568703.LGG_01867 1.92e-200 555.0 COG1409@1|root,COG1409@2|Bacteria,1VHY9@1239|Firmicutes,4HPAR@91061|Bacilli,3F3SW@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos NAGPHGKN_00023 568703.LGG_01866 0.0 952.0 COG3711@1|root,COG3711@2|Bacteria,1U47D@1239|Firmicutes,4IDYQ@91061|Bacilli,3F986@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - Mga NAGPHGKN_00024 568703.LGG_01865 0.0 2329.0 COG1196@1|root,COG1196@2|Bacteria,1U47E@1239|Firmicutes,4HDDE@91061|Bacilli,3FC1G@33958|Lactobacillaceae 91061|Bacilli D Domain of Unknown Function (DUF1542) - - - - - - - - - - - - DUF1542 NAGPHGKN_00025 568703.LGG_01864 0.0 1360.0 COG1506@1|root,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,3F59I@33958|Lactobacillaceae 91061|Bacilli E Prolyl oligopeptidase family yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 NAGPHGKN_00026 568703.LGG_01863 7.93e-178 496.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,3F4SE@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer NAGPHGKN_00027 568703.LGG_01862 2.49e-278 760.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,3F40F@33958|Lactobacillaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 NAGPHGKN_00028 568703.LGG_01861 2.79e-162 454.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,3F4D0@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein yvoA_2 - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA NAGPHGKN_00029 568703.LGG_01860 0.0 963.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase NAGPHGKN_00030 568703.LGG_01859 1.3e-284 778.0 COG1680@1|root,COG1680@2|Bacteria,1V0GX@1239|Firmicutes,4HCXH@91061|Bacilli,3F4TH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase NAGPHGKN_00031 568703.LGG_01858 5.9e-194 538.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,3F43Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase NAGPHGKN_00032 568703.LGG_01857 1.01e-275 754.0 COG1680@1|root,COG1680@2|Bacteria,1V0GX@1239|Firmicutes,4HCXH@91061|Bacilli,3F4TH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase NAGPHGKN_00033 568703.LGG_01855 0.0 1365.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase NAGPHGKN_00034 568703.LGG_01855 3.02e-82 265.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase NAGPHGKN_00035 568703.LGG_01854 2.37e-95 278.0 2E7AN@1|root,331U3@2|Bacteria,1VFU9@1239|Firmicutes,4HY33@91061|Bacilli,3FBB1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00036 568703.LGG_01853 1.88e-225 622.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F462@33958|Lactobacillaceae 91061|Bacilli S ABC transporter XK27_08835 - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind NAGPHGKN_00037 568703.LGG_01852 3.57e-175 493.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,3F40J@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family XK27_08840 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 NAGPHGKN_00038 568703.LGG_01851 1.59e-165 464.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,3F3NW@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein XK27_08845 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran NAGPHGKN_00039 568703.LGG_01850 8.49e-105 302.0 COG3091@1|root,COG3091@2|Bacteria,1V6NU@1239|Firmicutes,4HIHY@91061|Bacilli,3F703@33958|Lactobacillaceae 91061|Bacilli S Belongs to the SprT family ydcK - - ko:K03095 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT NAGPHGKN_00040 568703.LGG_01849 1.4e-105 305.0 COG0454@1|root,COG0456@2|Bacteria,1VEF8@1239|Firmicutes,4IFXF@91061|Bacilli,3F77Z@33958|Lactobacillaceae 91061|Bacilli K FR47-like protein - - - - - - - - - - - - Acetyltransf_1 NAGPHGKN_00042 568703.LGG_01847 6.88e-129 367.0 COG4684@1|root,COG4684@2|Bacteria,1VB4T@1239|Firmicutes,4HMUC@91061|Bacilli,3F497@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt NAGPHGKN_00043 568703.LGG_01846 4.58e-269 737.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 NAGPHGKN_00044 568703.LGG_01845 2.96e-204 564.0 COG2017@1|root,COG2017@2|Bacteria,1U7B1@1239|Firmicutes,4IH61@91061|Bacilli,3F98X@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase - - - - - - - - - - - - Aldose_epim NAGPHGKN_00045 568703.LGG_01842 1.49e-132 375.0 COG1787@1|root,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,4HM6M@91061|Bacilli,3F8C4@33958|Lactobacillaceae 91061|Bacilli V Restriction endonuclease - - - ko:K07448 - - - - ko00000,ko02048 - - - Mrr_cat NAGPHGKN_00046 568703.LGG_01841 5.52e-204 563.0 COG1082@1|root,COG1082@2|Bacteria,1VSC9@1239|Firmicutes,4HUQI@91061|Bacilli,3F4RS@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 NAGPHGKN_00047 568703.LGG_01840 6.7e-62 190.0 2B6X8@1|root,31ZX5@2|Bacteria,1U6HZ@1239|Firmicutes,4IGAA@91061|Bacilli,3F7YC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00048 568703.LGG_01839 7.3e-268 735.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,3F3Q5@33958|Lactobacillaceae 91061|Bacilli I Belongs to the thiolase family atoB - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red,Thiolase_C,Thiolase_N NAGPHGKN_00049 568703.LGG_01838 4.29e-265 730.0 COG1257@1|root,COG1257@2|Bacteria,1TPNY@1239|Firmicutes,4HBQ3@91061|Bacilli,3F3YY@33958|Lactobacillaceae 91061|Bacilli C Belongs to the HMG-CoA reductase family mvaA - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red NAGPHGKN_00050 568703.LGG_01837 8.72e-279 762.0 COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli,3F425@33958|Lactobacillaceae 91061|Bacilli I Hydroxymethylglutaryl-CoA synthase mvaS - 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 - - - HMG_CoA_synt_C,HMG_CoA_synt_N NAGPHGKN_00052 568703.LGG_01836 0.0 1161.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family poxL - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N NAGPHGKN_00053 568703.LGG_01835 2.78e-103 299.0 COG3613@1|root,COG3613@2|Bacteria,1V3SN@1239|Firmicutes,4HH4T@91061|Bacilli,3F6KR@33958|Lactobacillaceae 91061|Bacilli F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr NAGPHGKN_00054 568703.LGG_01834 0.0 889.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F4GQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr NAGPHGKN_00055 568703.LGG_01833 2.24e-84 249.0 29Q60@1|root,30B4X@2|Bacteria,1U7J8@1239|Firmicutes,4IHG5@91061|Bacilli,3F9T1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00056 568703.LGG_01832 0.0 1004.0 COG3711@1|root,COG3711@2|Bacteria,1U7FC@1239|Firmicutes,4IHBC@91061|Bacilli,3F9IX@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - Mga NAGPHGKN_00057 568703.LGG_01831 7.6e-176 491.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,3F4BY@33958|Lactobacillaceae 91061|Bacilli S Regulatory protein RecX recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX NAGPHGKN_00058 568703.LGG_01830 1.73e-134 380.0 COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli,3F48S@33958|Lactobacillaceae 91061|Bacilli J Belongs to the UPF0374 family ygaC - - ko:K07586 - - - - ko00000 - - - DUF402 NAGPHGKN_00059 568703.LGG_01829 1.16e-124 354.0 29NVN@1|root,30AEE@2|Bacteria,1U6J7@1239|Firmicutes,4IGBR@91061|Bacilli,3F80T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00060 568703.LGG_01828 1.96e-98 286.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,3F6HQ@33958|Lactobacillaceae 91061|Bacilli S Acetyltransferase (GNAT) domain yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 NAGPHGKN_00061 568703.LGG_01827 4.36e-264 725.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3F418@33958|Lactobacillaceae 91061|Bacilli S AI-2E family transporter yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport NAGPHGKN_00062 568703.LGG_01826 1.88e-307 840.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3KG@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain hlyX - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 NAGPHGKN_00063 568703.LGG_01825 0.0 1045.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,3F489@33958|Lactobacillaceae 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C NAGPHGKN_00064 568703.LGG_01824 2.87e-62 191.0 2EBZ8@1|root,335YI@2|Bacteria,1VFRS@1239|Firmicutes,4HNUK@91061|Bacilli,3F70G@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1827) XK27_09445 - - - - - - - - - - - DUF1827 NAGPHGKN_00065 568703.LGG_01823 0.0 1300.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F3K9@33958|Lactobacillaceae 91061|Bacilli O Belongs to the ClpA ClpB family clpE - - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR NAGPHGKN_00066 1423816.BACQ01000003_gene57 6.69e-39 129.0 2EI19@1|root,33BSS@2|Bacteria,1VKXC@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - NAGPHGKN_00067 1423732.BALS01000007_gene584 1.02e-51 163.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,3F6XQ@33958|Lactobacillaceae 91061|Bacilli G phosphocarrier protein HPR ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr NAGPHGKN_00068 568703.LGG_01820 0.0 1102.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,3F3MS@33958|Lactobacillaceae 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C NAGPHGKN_00069 568703.LGG_00891 2.98e-18 78.2 2BT3F@1|root,32N80@2|Bacteria,1U8CV@1239|Firmicutes,4IIAU@91061|Bacilli,3FAUG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00070 568703.LGG_01817 0.0 874.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,3F3ZS@33958|Lactobacillaceae 91061|Bacilli EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family iolT GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K06609 - - - - ko00000,ko02000 2.A.1.1.26 - - Sugar_tr NAGPHGKN_00072 568703.LGG_01815 2.72e-135 384.0 COG3859@1|root,COG3859@2|Bacteria,1V6YE@1239|Firmicutes,4HIJE@91061|Bacilli,3F738@33958|Lactobacillaceae 91061|Bacilli S Thiamine transporter protein (Thia_YuaJ) thiT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K16789 - - - - ko00000,ko02000 2.A.88.3 - - Thia_YuaJ NAGPHGKN_00073 568703.LGG_01814 6.02e-104 301.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,3F6P0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC NAGPHGKN_00074 568703.LGG_01813 5.81e-272 743.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,3F3YV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp NAGPHGKN_00075 568703.LGG_01812 1.9e-171 478.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli,3F44Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt NAGPHGKN_00076 568703.LGG_01811 5.52e-55 171.0 COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,3F81F@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU06460 PurS NAGPHGKN_00077 568703.LGG_01810 3.56e-167 466.0 COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,3F48D@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 NAGPHGKN_00078 568703.LGG_01809 0.0 1463.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,3F4IQ@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C NAGPHGKN_00079 568703.LGG_01808 0.0 958.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,3F3U7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran NAGPHGKN_00080 568703.LGG_01807 6.18e-238 654.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,3F4RT@33958|Lactobacillaceae 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C NAGPHGKN_00081 568703.LGG_01806 9.63e-130 369.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli,3F3UN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N NAGPHGKN_00082 568703.LGG_01805 3.93e-241 670.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,3F4FD@33958|Lactobacillaceae 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS NAGPHGKN_00085 1423732.BALS01000058_gene2814 1.37e-270 740.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HA65@91061|Bacilli,3F3NJ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family int3 - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase NAGPHGKN_00086 1423816.BACQ01000027_gene972 3.71e-94 280.0 2B0Y6@1|root,31TB7@2|Bacteria,1V6RK@1239|Firmicutes,4HK0B@91061|Bacilli,3F920@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00087 1423816.BACQ01000027_gene971 5.96e-131 375.0 COG2932@1|root,COG2932@2|Bacteria 2|Bacteria K sequence-specific DNA binding XK27_10050 - - - - - - - - - - - HTH_19,HTH_3,Peptidase_S24 NAGPHGKN_00089 1423775.BAMN01000009_gene432 1.11e-121 355.0 COG1737@1|root,COG1737@2|Bacteria,1UI8Z@1239|Firmicutes,4HQMK@91061|Bacilli,3FBT0@33958|Lactobacillaceae 91061|Bacilli K ORF6N domain - - - - - - - - - - - - ORF6N NAGPHGKN_00094 39103.U5U3Y3_9CAUD 3.67e-198 550.0 4QB3F@10239|Viruses,4QV3C@35237|dsDNA viruses no RNA stage,4QPZ0@28883|Caudovirales,4QM6P@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF1351) - - - - - - - - - - - - - NAGPHGKN_00095 755164.D6PSU1_9CAUD 8.32e-51 172.0 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales 28883|Caudovirales S ERF superfamily - - - - - - - - - - - - - NAGPHGKN_00096 39103.U5U4M2_9CAUD 1.15e-161 452.0 4QFVV@10239|Viruses,4QYK6@35237|dsDNA viruses no RNA stage,4QSUK@28883|Caudovirales,4QN2Q@10699|Siphoviridae 10699|Siphoviridae S Pfam:HNHc_6 - - - - - - - - - - - - - NAGPHGKN_00097 39103.U5U726_9CAUD 2.14e-81 243.0 4QAU9@10239|Viruses,4QVR2@35237|dsDNA viruses no RNA stage,4QQV4@28883|Caudovirales,4QKUJ@10699|Siphoviridae 10699|Siphoviridae S Single-strand binding protein family - - - - - - - - - - - - - NAGPHGKN_00098 39103.U5U793_9CAUD 1.4e-143 411.0 4QAX8@10239|Viruses,4QVB1@35237|dsDNA viruses no RNA stage,4QPHH@28883|Caudovirales,4QMNN@10699|Siphoviridae 10699|Siphoviridae S calcium ion binding - - - - - - - - - - - - - NAGPHGKN_00099 39103.U5U3Y9_9CAUD 6.62e-296 808.0 4QAWG@10239|Viruses,4QV6X@35237|dsDNA viruses no RNA stage,4QPII@28883|Caudovirales,4QKWY@10699|Siphoviridae 10699|Siphoviridae S DNA helicase activity - - - - - - - - - - - - - NAGPHGKN_00102 543734.LCABL_13130 7.11e-48 153.0 29Q9N@1|root,30B8R@2|Bacteria,1U7R2@1239|Firmicutes,4IHNC@91061|Bacilli,3FA1N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00103 39103.U5U799_9CAUD 9.27e-86 252.0 4QB0C@10239|Viruses,4QZIU@35237|dsDNA viruses no RNA stage,4QPK3@28883|Caudovirales,4QKQC@10699|Siphoviridae 10699|Siphoviridae S magnesium ion binding - - - - - - - - - - - - - NAGPHGKN_00104 146269.A8YQM6_9CAUD 9.79e-132 380.0 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QM02@10699|Siphoviridae 10699|Siphoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - NAGPHGKN_00105 146269.A8YQM7_9CAUD 9.34e-162 453.0 4QC87@10239|Viruses,4QUN8@35237|dsDNA viruses no RNA stage,4QRGW@28883|Caudovirales,4QMER@10699|Siphoviridae 10699|Siphoviridae S DNA methylation - - - - - - - - - - - - - NAGPHGKN_00107 1423732.BALS01000058_gene2831 7.03e-62 196.0 29Q9Z@1|root,30B93@2|Bacteria,1U7RI@1239|Firmicutes,4IHNV@91061|Bacilli,3FA2I@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1642) - - - - - - - - - - - - DUF1642 NAGPHGKN_00108 568703.LGG_01117 5.89e-46 150.0 29Q9M@1|root,30B8Q@2|Bacteria,1U7QY@1239|Firmicutes,4IHN8@91061|Bacilli,3FA1A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00113 543734.LCABL_05720 4.4e-101 293.0 2DCNS@1|root,2ZESF@2|Bacteria,1W51N@1239|Firmicutes,4I1NU@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00114 1423816.BACQ01000027_gene951 4.69e-201 557.0 29WKP@1|root,30A22@2|Bacteria,1U636@1239|Firmicutes,4IFSG@91061|Bacilli,3F6XH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00115 543734.LCABL_13210 5.68e-280 764.0 2C1BV@1|root,32ZTD@2|Bacteria,1VGE5@1239|Firmicutes,4HPF9@91061|Bacilli,3F9J1@33958|Lactobacillaceae 91061|Bacilli S GcrA cell cycle regulator - - - - - - - - - - - - GcrA NAGPHGKN_00116 39103.U5U4N5_9CAUD 1.9e-76 233.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - NAGPHGKN_00117 543734.LCABL_05780 2.66e-60 186.0 2BWYP@1|root,30AJY@2|Bacteria,1U6SS@1239|Firmicutes,4IGKB@91061|Bacilli,3F8F9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00119 349123.Lreu23DRAFT_3876 1.02e-90 276.0 COG1403@1|root,COG1403@2|Bacteria,1VQIP@1239|Firmicutes,4HM74@91061|Bacilli,3F6KP@33958|Lactobacillaceae 91061|Bacilli L HNH nucleases - - - - - - - - - - - - AAA_33,HNH NAGPHGKN_00120 39103.U5U3Z1_9CAUD 4.9e-100 290.0 4QBS6@10239|Viruses,4QUNW@35237|dsDNA viruses no RNA stage,4QPP2@28883|Caudovirales 28883|Caudovirales S Phage terminase, small subunit - - - - - - - - - - - - - NAGPHGKN_00121 51369.Q8LTC3_9CAUD 0.0 1109.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - NAGPHGKN_00123 39103.U5U764_9CAUD 2.08e-302 824.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - NAGPHGKN_00124 51369.Q8LTC1_9CAUD 3.57e-144 407.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0003674,GO:0003824,GO:0005575,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019012,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - - - - - - - - - - - NAGPHGKN_00125 39103.U5U4N8_9CAUD 2.82e-262 725.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098026 - - - - - - - - - - - NAGPHGKN_00126 39103.U5U4N8_9CAUD 2.07e-20 90.9 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098026 - - - - - - - - - - - NAGPHGKN_00127 1231336.L248_1694 3.09e-36 126.0 2EEUA@1|root,30AEZ@2|Bacteria,1U6JX@1239|Firmicutes,4IGCG@91061|Bacilli,3F824@33958|Lactobacillaceae 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 NAGPHGKN_00128 1231336.L248_1695 1.13e-51 165.0 2DKS7@1|root,30AKM@2|Bacteria,1U6TU@1239|Firmicutes,4IGMN@91061|Bacilli,3F8H9@33958|Lactobacillaceae 91061|Bacilli S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join NAGPHGKN_00129 51369.P94214_9CAUD 7.74e-86 253.0 4QB1F@10239|Viruses,4QUYH@35237|dsDNA viruses no RNA stage,4QPSW@28883|Caudovirales,4QKPW@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - NAGPHGKN_00130 1231336.L248_1697 7.57e-38 132.0 29PDS@1|root,30ABY@2|Bacteria,1U6G0@1239|Firmicutes,4IG81@91061|Bacilli,3F7U0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00131 947980.E9LUI9_9CAUD 2.29e-92 275.0 4QAYN@10239|Viruses,4QUR7@35237|dsDNA viruses no RNA stage,4QPCU@28883|Caudovirales,4QKPS@10699|Siphoviridae 10699|Siphoviridae S Pfam:Phage_TTP_1 - - - - - - - - - - - - - NAGPHGKN_00132 1231336.L248_1700 2.72e-27 105.0 29PXI@1|root,30AVX@2|Bacteria,1U768@1239|Firmicutes,4IH0Z@91061|Bacilli,3F912@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00133 39103.U5U708_9CAUD 0.0 1981.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0016032,GO:0019058,GO:0019068,GO:0044403,GO:0044419,GO:0051704,GO:0098003 - - - - - - - - - - - NAGPHGKN_00134 1423732.BALS01000073_gene2082 9.24e-305 848.0 29YVX@1|root,30KSC@2|Bacteria,1UPK5@1239|Firmicutes,4IV6C@91061|Bacilli,3F9DD@33958|Lactobacillaceae 1423732.BALS01000073_gene2082|- S Phage tail protein - - - - - - - - - - - - - NAGPHGKN_00135 146269.A8YQK1_9CAUD 0.0 1532.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - NAGPHGKN_00136 146269.A8YQK2_9CAUD 5.89e-63 193.0 4QH1E@10239|Viruses,4QZAD@35237|dsDNA viruses no RNA stage,4QSYR@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - NAGPHGKN_00138 543734.LCABL_13450 7.87e-69 208.0 2EN82@1|root,33FVV@2|Bacteria,1VKRH@1239|Firmicutes,4HR3G@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00139 543734.LCABL_13460 1.24e-65 203.0 COG5546@1|root,COG5546@2|Bacteria,1VGGV@1239|Firmicutes,4HPNN@91061|Bacilli,3F9QK@33958|Lactobacillaceae 91061|Bacilli S Bacteriophage holin hol - - - - - - - - - - - Phage_holin_1 NAGPHGKN_00140 543734.LCABL_13470 1.22e-231 643.0 COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V16P@1239|Firmicutes,4HF99@91061|Bacilli,3FC13@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25,LysM,SH3_5 NAGPHGKN_00142 568703.LGG_00841 1e-138 394.0 29Q2N@1|root,30B1A@2|Bacteria,1U7D8@1239|Firmicutes,4IH94@91061|Bacilli,3F9EU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00143 568703.LGG_00842 1.66e-269 739.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,3F3T0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N NAGPHGKN_00144 568703.LGG_00843 0.0 944.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator mdr - - - - - - - - - - - MFS_1 NAGPHGKN_00145 568703.LGG_00844 3.41e-107 309.0 COG0789@1|root,COG0789@2|Bacteria,1VDPP@1239|Firmicutes,4HPJY@91061|Bacilli,3F6MS@33958|Lactobacillaceae 91061|Bacilli K MerR HTH family regulatory protein - - - - - - - - - - - - MerR_1 NAGPHGKN_00146 568703.LGG_00845 0.0 916.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 NAGPHGKN_00147 568703.LGG_00846 7.22e-153 431.0 2C9UQ@1|root,32RPZ@2|Bacteria,1VDDQ@1239|Firmicutes,4HNJB@91061|Bacilli,3F5X9@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4811) - - - - - - - - - - - - DUF4811 NAGPHGKN_00148 568703.LGG_00847 2.47e-154 434.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,3F5CM@33958|Lactobacillaceae 91061|Bacilli I Acid phosphatase homologues yodM - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 NAGPHGKN_00149 568703.LGG_00848 0.0 1670.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,3F46M@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 NAGPHGKN_00150 568703.LGG_00851 2.42e-104 316.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,3F404@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C NAGPHGKN_00151 568703.LGG_00851 2.1e-213 601.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,3F404@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C NAGPHGKN_00152 568703.LGG_00852 6.61e-167 466.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,3F41G@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 NAGPHGKN_00153 568703.LGG_00853 8.09e-48 152.0 COG3478@1|root,COG3478@2|Bacteria,1VEIV@1239|Firmicutes,4HPKA@91061|Bacilli,3FAC9@33958|Lactobacillaceae 91061|Bacilli S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) yhcC - - ko:K07069 - - - - ko00000 - - - zinc_ribbon_13 NAGPHGKN_00154 568703.LGG_00854 2.06e-174 489.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,3F480@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N NAGPHGKN_00155 568703.LGG_00855 9.29e-123 350.0 COG1051@1|root,COG1051@2|Bacteria,1VDM3@1239|Firmicutes,4HMI0@91061|Bacilli,3F6RN@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX NAGPHGKN_00157 568703.LGG_00856 3.41e-112 322.0 COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli,3F6A9@33958|Lactobacillaceae 91061|Bacilli O Belongs to the glutathione peroxidase family gpo - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx NAGPHGKN_00158 568703.LGG_00857 8.63e-287 783.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 NAGPHGKN_00159 1423816.BACQ01000026_gene903 5.43e-281 772.0 COG1409@1|root,COG1409@2|Bacteria,1UQCQ@1239|Firmicutes,4HG8Z@91061|Bacilli,3F483@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase cpdA - - - - - - - - - - - Metallophos NAGPHGKN_00160 568703.LGG_00860 1.19e-50 160.0 COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,4HNJ4@91061|Bacilli,3F811@33958|Lactobacillaceae 91061|Bacilli T Belongs to the UPF0237 family XK27_08630 - - ko:K07166 - - - - ko00000 - - - ACT_6 NAGPHGKN_00161 568703.LGG_00861 3.14e-310 847.0 COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,4HBTU@91061|Bacilli,3F4H2@33958|Lactobacillaceae 91061|Bacilli S UPF0210 protein XK27_08635 - - ko:K09157 - - - - ko00000 - - - DUF711 NAGPHGKN_00162 568703.LGG_00862 1.12e-270 739.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA NAGPHGKN_00163 568703.LGG_00863 8.12e-151 424.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,3F6QR@33958|Lactobacillaceae 91061|Bacilli Q Thioredoxin yjbH - - - - - - - - - - - Thioredoxin_5 NAGPHGKN_00164 568703.LGG_00864 8.17e-135 382.0 COG4116@1|root,COG4116@2|Bacteria,1TTVM@1239|Firmicutes,4I4A3@91061|Bacilli,3F4YS@33958|Lactobacillaceae 91061|Bacilli S CYTH - - - - - - - - - - - - CYTH NAGPHGKN_00165 568703.LGG_00865 4.15e-160 448.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,3F452@33958|Lactobacillaceae 91061|Bacilli S RelA SpoT domain protein yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT NAGPHGKN_00166 568703.LGG_00866 2.24e-193 536.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,3F45D@33958|Lactobacillaceae 91061|Bacilli F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase NAGPHGKN_00167 568703.LGG_00867 5.18e-221 608.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3F4AU@33958|Lactobacillaceae 91061|Bacilli G Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 NAGPHGKN_00168 568703.LGG_00868 3.99e-258 707.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HA6Y@91061|Bacilli,3FB4B@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE NAGPHGKN_00169 568703.LGG_00869 1.51e-144 408.0 COG3142@1|root,COG3142@2|Bacteria,1TQYI@1239|Firmicutes,4HE1E@91061|Bacilli,3F4NZ@33958|Lactobacillaceae 91061|Bacilli P Participates in the control of copper homeostasis cutC - - ko:K06201 - - - - ko00000 - - - CutC NAGPHGKN_00170 568703.LGG_00870 1.61e-185 516.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli,3F510@33958|Lactobacillaceae 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA NAGPHGKN_00171 568703.LGG_00871 3.13e-252 691.0 COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,3F3RC@33958|Lactobacillaceae 91061|Bacilli G Lactonase, 7-bladed beta-propeller pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase NAGPHGKN_00172 568703.LGG_00872 7.55e-82 242.0 COG3731@1|root,COG3731@2|Bacteria,1VGKB@1239|Firmicutes,4HNJN@91061|Bacilli,3F8EZ@33958|Lactobacillaceae 91061|Bacilli G PTS system glucitol/sorbitol-specific IIA component srlB - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA NAGPHGKN_00173 1423732.BALS01000004_gene1205 4.12e-56 174.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HKK1@91061|Bacilli,3F7KX@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 NAGPHGKN_00174 568703.LGG_00874 9.97e-245 671.0 COG0516@1|root,COG0516@2|Bacteria,1TNYF@1239|Firmicutes,4HA55@91061|Bacilli,3F45K@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaC - 1.7.1.7 ko:K00364 ko00230,map00230 - R01134 RC00457 ko00000,ko00001,ko01000 - - iSB619.SA_RS06660 IMPDH NAGPHGKN_00175 568703.LGG_00875 9.63e-220 607.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,3F4B8@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA NAGPHGKN_00176 568703.LGG_00876 9.45e-198 548.0 COG0500@1|root,COG2226@2|Bacteria,1V1WE@1239|Firmicutes,4HGQ9@91061|Bacilli,3F4U3@33958|Lactobacillaceae 91061|Bacilli H Methyltransferase rrmA - 2.1.1.187 ko:K00563,ko:K10947 - - R07233 RC00003 ko00000,ko01000,ko03000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 NAGPHGKN_00177 568703.LGG_00878 6.48e-125 355.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,3F42Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase NAGPHGKN_00178 568703.LGG_00879 2.93e-30 109.0 COG4835@1|root,COG4835@2|Bacteria,1VJ7H@1239|Firmicutes,4HP0P@91061|Bacilli,3F6JB@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1149) - - - - - - - - - - - - DUF1149 NAGPHGKN_00179 568703.LGG_00879 2.41e-51 164.0 COG4835@1|root,COG4835@2|Bacteria,1VJ7H@1239|Firmicutes,4HP0P@91061|Bacilli,3F6JB@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1149) - - - - - - - - - - - - DUF1149 NAGPHGKN_00180 568703.LGG_01975 0.0 1465.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,3F486@33958|Lactobacillaceae 91061|Bacilli L DNA helicase helD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 NAGPHGKN_00181 568703.LGG_01974 6.86e-108 311.0 COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,3F6A3@33958|Lactobacillaceae 91061|Bacilli I Thioesterase superfamily ykhA - 3.1.2.20 ko:K01073 - - - - ko00000,ko01000 - - - 4HBT NAGPHGKN_00182 568703.LGG_01972 0.0 951.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepDA - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 NAGPHGKN_00183 568703.LGG_01971 2.59e-55 173.0 2AHIU@1|root,317WG@2|Bacteria,1U84D@1239|Firmicutes,4II1U@91061|Bacilli,3FAIH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00184 568703.LGG_01970 4.69e-70 212.0 2BU50@1|root,32PDW@2|Bacteria,1U8GV@1239|Firmicutes,4IIEQ@91061|Bacilli,3FAYY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00185 568703.LGG_01969 3.82e-227 625.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli,3F42Q@33958|Lactobacillaceae 91061|Bacilli F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK NAGPHGKN_00186 1423816.BACQ01000047_gene1771 0.0 1030.0 COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,3F3NV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase NAGPHGKN_00187 1138822.PL11_10340 4.52e-54 185.0 2BHI8@1|root,32BKM@2|Bacteria,1U6MY@1239|Firmicutes,4IGER@91061|Bacilli,3F867@33958|Lactobacillaceae 91061|Bacilli S Abortive infection C-terminus - - - - - - - - - - - - Abi_C NAGPHGKN_00189 1449343.JQLQ01000002_gene120 9.19e-96 299.0 COG2865@1|root,COG2865@2|Bacteria,1UYYR@1239|Firmicutes,4HHVE@91061|Bacilli,27HKY@186828|Carnobacteriaceae 91061|Bacilli K Putative DNA-binding domain - - - - - - - - - - - - AlbA_2 NAGPHGKN_00190 861455.HMPREF9184_01752 1.85e-67 218.0 2DNGW@1|root,32XFG@2|Bacteria,1VMS1@1239|Firmicutes,4HVF1@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00191 904293.HMPREF9176_0570 5.86e-16 86.7 COG1388@1|root,COG1388@2|Bacteria,1VQJH@1239|Firmicutes,4HSU2@91061|Bacilli 91061|Bacilli M LysM domain - - - - - - - - - - - - LysM NAGPHGKN_00197 220668.lp_2654 9.36e-35 122.0 COG1396@1|root,COG1396@2|Bacteria,1V3D7@1239|Firmicutes,4IGD5@91061|Bacilli,3F83A@33958|Lactobacillaceae 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 NAGPHGKN_00199 1007096.BAGW01000014_gene1082 1.29e-44 157.0 COG4974@1|root,COG4974@2|Bacteria,1V2WH@1239|Firmicutes,24GXU@186801|Clostridia,2N89Y@216572|Oscillospiraceae 186801|Clostridia L Plasmid pRiA4b ORF-3-like protein - - - - - - - - - - - - PRiA4_ORF3 NAGPHGKN_00200 575605.ACQN01000001_gene347 1.55e-117 347.0 COG1715@1|root,COG1715@2|Bacteria,1V7W8@1239|Firmicutes,4HHU7@91061|Bacilli,3F4T4@33958|Lactobacillaceae 91061|Bacilli L restriction endonuclease - - - ko:K07448 - - - - ko00000,ko02048 - - - Mrr_N,Mrr_cat NAGPHGKN_00201 568703.LGG_01954 6.65e-64 196.0 2DCPK@1|root,2ZEV0@2|Bacteria,1TVRG@1239|Firmicutes,4I3X9@91061|Bacilli,3FA25@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain lciIC - - - - - - - - - - - HTH_3 NAGPHGKN_00203 568703.LGG_01953 0.0 1767.0 COG1388@1|root,COG1388@2|Bacteria,1VQJH@1239|Firmicutes,4HSU2@91061|Bacilli,3F4H3@33958|Lactobacillaceae 91061|Bacilli M LysM domain - - - - - - - - - - - - LysM NAGPHGKN_00205 936140.AEOT01000001_gene2370 4.47e-32 112.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli,3F85E@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 NAGPHGKN_00206 568703.LGG_01952 3e-154 436.0 COG5549@1|root,COG5549@2|Bacteria,1V6X9@1239|Firmicutes,4HK8S@91061|Bacilli,3F6QI@33958|Lactobacillaceae 91061|Bacilli O Zinc-dependent metalloprotease zmp3 - - - - - - - - - - - Peptidase_M10 NAGPHGKN_00207 568703.LGG_01951 6.03e-175 491.0 2DQV2@1|root,338VR@2|Bacteria,1VG1G@1239|Firmicutes,4HQEQ@91061|Bacilli,3F9IH@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase enzyme family - - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH NAGPHGKN_00208 568703.LGG_01949 1.87e-88 259.0 2F916@1|root,309SE@2|Bacteria,1U5KS@1239|Firmicutes,4IFBR@91061|Bacilli,3F65Y@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn NAGPHGKN_00209 568703.LGG_01948 0.0 971.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F4HU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06147,ko:K06148,ko:K11085,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NAGPHGKN_00210 568703.LGG_01947 0.0 1001.0 COG1132@1|root,COG1132@2|Bacteria,1UVV5@1239|Firmicutes,4I2V1@91061|Bacilli,3F9E9@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran NAGPHGKN_00211 568703.LGG_01946 6.2e-48 154.0 28QAQ@1|root,2ZCTB@2|Bacteria,1W6HR@1239|Firmicutes,4I0FP@91061|Bacilli,3F7NS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00212 568703.LGG_01945 0.0 1038.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HTMF@91061|Bacilli,3F9QE@33958|Lactobacillaceae 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 NAGPHGKN_00213 568703.LGG_01944 5.52e-215 595.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HU8D@91061|Bacilli,3F9HF@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 NAGPHGKN_00214 568703.LGG_01943 3.48e-219 605.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,3F9AC@33958|Lactobacillaceae 91061|Bacilli P N-terminal TM domain of oligopeptide transport permease C - - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N NAGPHGKN_00215 568703.LGG_01942 5.22e-65 198.0 2AHSP@1|root,31856@2|Bacteria,1U7RZ@1239|Firmicutes,4IHPB@91061|Bacilli,3FA3D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00216 568703.LGG_01941 3.1e-247 679.0 COG0444@1|root,COG0444@2|Bacteria,1VRIF@1239|Firmicutes,4HV11@91061|Bacilli,3F96N@33958|Lactobacillaceae 91061|Bacilli P Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY NAGPHGKN_00217 568703.LGG_01940 2.84e-207 573.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4HUP0@91061|Bacilli,3F9A0@33958|Lactobacillaceae 91061|Bacilli P Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY NAGPHGKN_00218 1300150.EMQU_1517 7.16e-113 330.0 COG1136@1|root,COG1136@2|Bacteria,1VU5E@1239|Firmicutes,4HV26@91061|Bacilli,4B2U2@81852|Enterococcaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_00219 1158607.UAU_01174 1.9e-193 552.0 2EYF6@1|root,33RP4@2|Bacteria,1VSYT@1239|Firmicutes,4HVCU@91061|Bacilli,4B49Z@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00221 568703.LGG_01938 1.49e-164 461.0 COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HC2V@91061|Bacilli,3FC3Q@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities yhcG - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_00222 568703.LGG_01937 5.73e-82 243.0 COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,4HPK4@91061|Bacilli,3F6GC@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, GntR family lexA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR NAGPHGKN_00223 568703.LGG_01936 6.17e-203 561.0 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 NAGPHGKN_00224 568703.LGG_01935 2.15e-237 654.0 COG1476@1|root,COG1476@2|Bacteria,1V7TA@1239|Firmicutes,4HWM9@91061|Bacilli,3FCE2@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 NAGPHGKN_00225 568703.LGG_01934 6.02e-163 457.0 COG0730@1|root,COG0730@2|Bacteria,1V75K@1239|Firmicutes,4HEE8@91061|Bacilli,3F6BU@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE NAGPHGKN_00226 568703.LGG_01933 0.0 886.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator ypiB - - - - - - - - - - - MFS_1 NAGPHGKN_00227 568703.LGG_01932 9.85e-147 413.0 COG1309@1|root,COG1309@2|Bacteria,1VG1F@1239|Firmicutes,4HPER@91061|Bacilli,3F6KD@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_N NAGPHGKN_00228 568703.LGG_01931 0.0 1001.0 COG3559@1|root,COG3559@2|Bacteria,1TPIG@1239|Firmicutes,4H9SK@91061|Bacilli,3F4PV@33958|Lactobacillaceae 91061|Bacilli M Exporter of polyketide antibiotics - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - NAGPHGKN_00229 568703.LGG_01930 5.54e-214 591.0 COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,4HC34@91061|Bacilli,3F4JT@33958|Lactobacillaceae 91061|Bacilli V ABC transporter ybhF_1 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 NAGPHGKN_00230 568703.LGG_01929 5e-174 486.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,3F4IY@33958|Lactobacillaceae 91061|Bacilli C nitroreductase nfrA - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase NAGPHGKN_00231 1423816.BACQ01000046_gene1728 4.82e-83 258.0 COG4858@1|root,COG4858@2|Bacteria,1V9IF@1239|Firmicutes,4HKB8@91061|Bacilli,3F6UB@33958|Lactobacillaceae 91061|Bacilli - - ORF00048 - - - - - - - - - - - DUF1129 NAGPHGKN_00232 568703.LGG_01926 7.63e-74 221.0 COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,4HKBS@91061|Bacilli,3F70B@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family padR - - ko:K10947 - - - - ko00000,ko03000 - - - PadR NAGPHGKN_00233 568703.LGG_01925 1.29e-135 385.0 COG2085@1|root,COG2085@2|Bacteria 2|Bacteria S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored NAGPHGKN_00234 568703.LGG_01924 1.36e-112 323.0 COG0454@1|root,COG0456@2|Bacteria,1UM79@1239|Firmicutes,4ITT0@91061|Bacilli,3FBXP@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - - NAGPHGKN_00235 568703.LGG_01923 2.75e-123 352.0 COG1859@1|root,COG1859@2|Bacteria,1V49Y@1239|Firmicutes,4HHHZ@91061|Bacilli,3FBCQ@33958|Lactobacillaceae 91061|Bacilli J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase kptA - - ko:K07559 - - - - ko00000,ko01000,ko03016 - - - PTS_2-RNA NAGPHGKN_00236 568703.LGG_01922 4.38e-56 174.0 2ENWC@1|root,33GHC@2|Bacteria,1VPIM@1239|Firmicutes,4HRIM@91061|Bacilli,3F826@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00237 568703.LGG_01921 2.47e-308 842.0 COG2851@1|root,COG2851@2|Bacteria,1TQQH@1239|Firmicutes,4HAGT@91061|Bacilli,3F5EB@33958|Lactobacillaceae 91061|Bacilli C Citrate transporter citM - - ko:K03300 - - - - ko00000 2.A.11 - - CitMHS NAGPHGKN_00238 568703.LGG_01920 5.72e-69 208.0 2EDVU@1|root,337QZ@2|Bacteria,1W0WF@1239|Firmicutes,4HZEA@91061|Bacilli,3F82X@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00239 568703.LGG_01919 1.44e-57 182.0 COG0511@1|root,COG0511@2|Bacteria,1VW7S@1239|Firmicutes,4HJSW@91061|Bacilli,3F7V3@33958|Lactobacillaceae 91061|Bacilli I Biotin-requiring enzyme oadG - - - - - - - - - - - Biotin_lipoyl NAGPHGKN_00240 568703.LGG_01918 1.6e-250 689.0 COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,4HEF4@91061|Bacilli,3F61X@33958|Lactobacillaceae 91061|Bacilli C Na+-transporting oxaloacetate decarboxylase beta subunit oadB - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta NAGPHGKN_00241 1423747.BAMJ01000008_gene716 4.63e-07 47.8 29PZT@1|root,30AY8@2|Bacteria,1U79B@1239|Firmicutes,4IH46@91061|Bacilli,3F95A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00242 568703.LGG_01917 4.66e-232 639.0 COG3053@1|root,COG3053@2|Bacteria,1TSGQ@1239|Firmicutes,4HC6Q@91061|Bacilli,3F4H7@33958|Lactobacillaceae 91061|Bacilli H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase citC - 6.2.1.22 ko:K01910 ko02020,map02020 - R04449 RC00012,RC00039 ko00000,ko00001,ko01000 - - - Acetyltransf_10,Citrate_ly_lig NAGPHGKN_00243 568703.LGG_01916 4.85e-65 198.0 COG3052@1|root,COG3052@2|Bacteria,1VEZZ@1239|Firmicutes,4HNXD@91061|Bacilli,3F7FR@33958|Lactobacillaceae 91061|Bacilli C Covalent carrier of the coenzyme of citrate lyase citD - - ko:K01646 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001 - - - ACP NAGPHGKN_00244 568703.LGG_01915 2.5e-199 553.0 COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,4HD40@91061|Bacilli,3F47Q@33958|Lactobacillaceae 91061|Bacilli G Belongs to the HpcH HpaI aldolase family citE - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI NAGPHGKN_00245 568703.LGG_01914 0.0 974.0 COG3051@1|root,COG3051@2|Bacteria,1TPN3@1239|Firmicutes,4HAE1@91061|Bacilli,3F4EA@33958|Lactobacillaceae 91061|Bacilli H Citrate (pro-3S)-lyase alpha chain citF - 2.8.3.10 ko:K01643 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - CitF NAGPHGKN_00246 568703.LGG_01913 4.83e-131 371.0 COG3697@1|root,COG3697@2|Bacteria,1VB3E@1239|Firmicutes,4HMZ5@91061|Bacilli,3F74S@33958|Lactobacillaceae 91061|Bacilli HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase citX - 2.7.7.61 ko:K05964 ko02020,map02020 - R10706 - ko00000,ko00001,ko01000 - - - CitX NAGPHGKN_00247 568703.LGG_01912 0.0 917.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,4HBJ1@91061|Bacilli,3F58W@33958|Lactobacillaceae 91061|Bacilli C Conserved carboxylase domain oadA - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - HMGL-like,PYC_OADA NAGPHGKN_00248 568703.LGG_01911 6.87e-162 453.0 COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,4HATG@91061|Bacilli,3F532@33958|Lactobacillaceae 91061|Bacilli K FCD citR - - - - - - - - - - - FCD,GntR NAGPHGKN_00249 568703.LGG_01910 2.83e-202 560.0 COG1767@1|root,COG1767@2|Bacteria,1TQGQ@1239|Firmicutes,4HGCS@91061|Bacilli,3F4SU@33958|Lactobacillaceae 91061|Bacilli H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase citG - 2.4.2.52 ko:K05966 ko02020,map02020 - R09675 RC00049,RC00063 ko00000,ko00001,ko01000 - - - CitG NAGPHGKN_00250 568703.LGG_00381 4.44e-62 191.0 2BNCG@1|root,319DH@2|Bacteria,1U7PQ@1239|Firmicutes,4IHM1@91061|Bacilli,3F9ZP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00251 568703.LGG_01909 3.93e-90 264.0 2EIVY@1|root,33CM8@2|Bacteria,1VKJ5@1239|Firmicutes,4HRQ2@91061|Bacilli,3F7QM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00252 568703.LGG_01908 1.92e-83 253.0 2AIC8@1|root,318TE@2|Bacteria,1U7KZ@1239|Firmicutes,4IHI2@91061|Bacilli,3F9W0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00253 568703.LGG_01907 1.2e-199 552.0 COG0657@1|root,COG0657@2|Bacteria,1VEC5@1239|Firmicutes,4HKY6@91061|Bacilli,3F50A@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 NAGPHGKN_00254 568703.LGG_01906 3.21e-204 565.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3F46Z@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 NAGPHGKN_00255 1423732.BALS01000021_gene323 1.43e-25 94.7 COG0267@1|root,COG0267@2|Bacteria,1VGZK@1239|Firmicutes,4HSMA@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 NAGPHGKN_00256 568703.LGG_01903 1.42e-132 376.0 2BIND@1|root,32CVF@2|Bacteria,1U7HI@1239|Firmicutes,4IHE6@91061|Bacilli,3F9PY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00257 568703.LGG_01902 9.53e-241 662.0 COG4072@1|root,COG4072@2|Bacteria,1U7B4@1239|Firmicutes,4IH64@91061|Bacilli,3F993@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF916) - - - - - - - - - - - - DUF3324,DUF916 NAGPHGKN_00258 568703.LGG_01338 2.48e-57 177.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,3F7DV@33958|Lactobacillaceae 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 NAGPHGKN_00259 568703.LGG_01337 5.85e-47 151.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,3F7D8@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p NAGPHGKN_00260 568703.LGG_01336 7.05e-248 681.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,3F3TP@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta NAGPHGKN_00261 568703.LGG_01335 0.0 1442.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,3F3VT@33958|Lactobacillaceae 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B NAGPHGKN_00262 568703.LGG_01334 1.96e-147 416.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,3F7NP@33958|Lactobacillaceae 91061|Bacilli L Competence protein ComEA comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB NAGPHGKN_00263 568703.LGG_01333 2.04e-247 680.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,3F4KY@33958|Lactobacillaceae 91061|Bacilli T Belongs to the peptidase S16 family lon - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 NAGPHGKN_00264 568703.LGG_01332 2.96e-111 320.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,3F6YS@33958|Lactobacillaceae 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like NAGPHGKN_00265 568703.LGG_01331 2.89e-129 367.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,3F505@33958|Lactobacillaceae 91061|Bacilli L RNA methyltransferase, RsmD family rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 NAGPHGKN_00266 568703.LGG_01330 2.84e-75 225.0 COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli,3F70V@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2129) ylbG - - - - - - - - - - - DUF2129 NAGPHGKN_00267 568703.LGG_01329 0.0 2235.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,3F4U7@33958|Lactobacillaceae 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA NAGPHGKN_00268 568703.LGG_01328 3.76e-268 735.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,3F4IK@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE NAGPHGKN_00269 568703.LGG_01327 0.0 1199.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,3F3UK@33958|Lactobacillaceae 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 NAGPHGKN_00270 568703.LGG_01326 1.06e-186 519.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,3F5BB@33958|Lactobacillaceae 91061|Bacilli G Belongs to the inositol monophosphatase superfamily suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P NAGPHGKN_00271 568703.LGG_01325 8.74e-62 189.0 COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli,3F80A@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0223 family yktA - - - - - - - - - - - UPF0223 NAGPHGKN_00272 568703.LGG_01324 7.16e-201 557.0 COG0039@1|root,COG0039@2|Bacteria,1UFQZ@1239|Firmicutes,4IEWQ@91061|Bacilli,3F4RQ@33958|Lactobacillaceae 91061|Bacilli C L-malate dehydrogenase activity - - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - - NAGPHGKN_00273 568703.LGG_01323 1.55e-249 690.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,3F426@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase pdhD - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim NAGPHGKN_00274 1423732.BALS01000015_gene1655 1.43e-50 172.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,3F426@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase pdhD - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim NAGPHGKN_00275 543734.LCABL_15380 6.23e-314 865.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,3F3RR@33958|Lactobacillaceae 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding NAGPHGKN_00276 568703.LGG_01321 1.34e-231 637.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HA4H@91061|Bacilli,3F4RV@33958|Lactobacillaceae 91061|Bacilli C Transketolase, C-terminal domain protein pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14590 Transket_pyr,Transketolase_C NAGPHGKN_00277 568703.LGG_01320 1.65e-266 729.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PQ@91061|Bacilli,3F3JK@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase E1 component pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh NAGPHGKN_00278 568703.LGG_01319 8.12e-174 487.0 29Q2F@1|root,30B13@2|Bacteria,1U7D2@1239|Firmicutes,4IH8M@91061|Bacilli,3F9EB@33958|Lactobacillaceae 91061|Bacilli S E1-E2 ATPase - - - - - - - - - - - - E1-E2_ATPase NAGPHGKN_00279 568703.LGG_01315 1.96e-131 372.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HH0G@91061|Bacilli,3F3YH@33958|Lactobacillaceae 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase NAGPHGKN_00280 568703.LGG_01314 1.83e-35 122.0 29QQZ@1|root,30BQS@2|Bacteria,1U8HD@1239|Firmicutes,4IIF9@91061|Bacilli,3FAZK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00281 568703.LGG_01313 2.95e-96 281.0 2C389@1|root,2ZQCN@2|Bacteria,1VQPI@1239|Firmicutes,4I0G9@91061|Bacilli,3F79N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00283 568703.LGG_01312 4.07e-43 140.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,3F807@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 NAGPHGKN_00284 568703.LGG_01311 0.0 1102.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3TT@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL NAGPHGKN_00285 568703.LGG_01310 5.92e-235 645.0 COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,4HBUD@91061|Bacilli,3F5GQ@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat NAGPHGKN_00286 568703.LGG_01309 2.35e-311 846.0 COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes,4HD22@91061|Bacilli,3F5HJ@33958|Lactobacillaceae 91061|Bacilli S Sterol carrier protein domain - - - - - - - - - - - - Acetyltransf_9,SCP2_2 NAGPHGKN_00287 568703.LGG_01308 0.0 1587.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,3F44X@33958|Lactobacillaceae 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 NAGPHGKN_00288 568703.LGG_01307 8.3e-150 422.0 COG0457@1|root,COG0457@2|Bacteria,1VFGR@1239|Firmicutes,4IBSH@91061|Bacilli,3F4MD@33958|Lactobacillaceae 91061|Bacilli S repeat protein - - - - - - - - - - - - TPR_12,TPR_16,TPR_19,TPR_2,TPR_8 NAGPHGKN_00289 568703.LGG_01306 9.46e-159 444.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F3U3@33958|Lactobacillaceae 91061|Bacilli G phosphoglycerate mutase pgm6 - - - - - - - - - - - His_Phos_1 NAGPHGKN_00290 568703.LGG_01304 8.38e-278 758.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,3F4N5@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans NAGPHGKN_00291 568703.LGG_01303 0.0 1497.0 COG0178@1|root,COG0178@2|Bacteria,1TR1H@1239|Firmicutes,4H9RE@91061|Bacilli,3F50Y@33958|Lactobacillaceae 91061|Bacilli L ABC transporter uvrA2 - - - - - - - - - - - ABC_tran NAGPHGKN_00292 568703.LGG_01302 3.61e-77 229.0 2DHWG@1|root,32U9W@2|Bacteria,1VDSF@1239|Firmicutes,4HP9N@91061|Bacilli,3F7E3@33958|Lactobacillaceae 91061|Bacilli S Putative amino acid metabolism XK27_04120 - - - - - - - - - - - DUF1831 NAGPHGKN_00293 568703.LGG_01300 9.79e-279 762.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,3F3RF@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 NAGPHGKN_00294 568703.LGG_01299 3.94e-159 447.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,3F4HE@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 NAGPHGKN_00295 568703.LGG_01298 1.36e-46 150.0 2A67P@1|root,30AP5@2|Bacteria,1U6XT@1239|Firmicutes,4IGS2@91061|Bacilli,3F8PG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00296 568703.LGG_01297 1.56e-127 362.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,3F53J@33958|Lactobacillaceae 91061|Bacilli L ADP-ribose pyrophosphatase nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX NAGPHGKN_00297 568703.LGG_01296 9.37e-150 422.0 COG4915@1|root,COG4915@2|Bacteria,1VB0U@1239|Firmicutes,4HMAQ@91061|Bacilli,3F7AZ@33958|Lactobacillaceae 91061|Bacilli S 5-bromo-4-chloroindolyl phosphate hydrolysis protein - - - - - - - - - - - - Halogen_Hydrol NAGPHGKN_00298 568703.LGG_01295 8.52e-268 735.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,4H9Z6@91061|Bacilli,3F5KJ@33958|Lactobacillaceae 91061|Bacilli P Toxic anion resistance protein (TelA) yaaN - - - - - - - - - - - TelA NAGPHGKN_00299 568703.LGG_01294 1.28e-174 496.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F4D4@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator ydiC1 - - - - - - - - - - - MFS_1 NAGPHGKN_00300 568703.LGG_01294 3.04e-131 385.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F4D4@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator ydiC1 - - - - - - - - - - - MFS_1 NAGPHGKN_00301 568703.LGG_01293 6.09e-200 555.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 NAGPHGKN_00302 568703.LGG_01292 2.98e-49 156.0 COG1278@1|root,COG1278@2|Bacteria,1W688@1239|Firmicutes,4I1Y3@91061|Bacilli,3F81I@33958|Lactobacillaceae 91061|Bacilli K Cold shock protein cspB - - ko:K03704 - - - - ko00000,ko03000 - - - CSD NAGPHGKN_00303 568703.LGG_01291 0.0 1784.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,3F3X4@33958|Lactobacillaceae 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS NAGPHGKN_00304 568703.LGG_01291 4.1e-06 48.5 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,3F3X4@33958|Lactobacillaceae 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS NAGPHGKN_00305 568703.LGG_01290 2.93e-109 323.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HJYN@91061|Bacilli,3FC2J@33958|Lactobacillaceae 91061|Bacilli D DivIVA protein divIVA - - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA NAGPHGKN_00306 568703.LGG_01289 1.91e-185 515.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,3F48W@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein ylmH - - - - - - - - - - - S4 NAGPHGKN_00307 568703.LGG_01288 6.86e-60 184.0 COG0762@1|root,COG0762@2|Bacteria 2|Bacteria D integral membrane protein yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02221 - - - - ko00000,ko02044 - - - YGGT NAGPHGKN_00308 568703.LGG_01287 5.1e-102 295.0 COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,4HKIC@91061|Bacilli,3F7MQ@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF NAGPHGKN_00309 568703.LGG_01286 2.19e-290 794.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,3F4V1@33958|Lactobacillaceae 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin NAGPHGKN_00310 568703.LGG_01285 6.05e-307 838.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,3F413@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA NAGPHGKN_00311 568703.LGG_01284 4.67e-196 544.0 COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,3F406@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 NAGPHGKN_00312 568703.LGG_01283 3.84e-257 705.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,3F4FW@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 NAGPHGKN_00313 568703.LGG_01282 0.0 912.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,3F49W@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M NAGPHGKN_00314 568703.LGG_01281 3.67e-227 626.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,3F3YP@33958|Lactobacillaceae 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 NAGPHGKN_00315 568703.LGG_01280 0.0 1381.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,3F47N@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase NAGPHGKN_00316 568703.LGG_01279 8.26e-80 237.0 COG4839@1|root,COG4839@2|Bacteria 2|Bacteria D cell division protein FtsL ftsL - - - - - - - - - - - DivIC NAGPHGKN_00317 568703.LGG_01278 4.57e-217 600.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,3F3MF@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 NAGPHGKN_00318 568703.LGG_01277 1.61e-101 293.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,3F6K3@33958|Lactobacillaceae 91061|Bacilli K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ NAGPHGKN_00319 568703.LGG_01276 1.49e-70 213.0 29Q7N@1|root,30B6Q@2|Bacteria,1U7MX@1239|Firmicutes,4IHJ5@91061|Bacilli,3F9XF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00320 568703.LGG_01275 4.32e-14 65.1 29QPZ@1|root,30BPQ@2|Bacteria,1U8FB@1239|Firmicutes,4IID7@91061|Bacilli,3FAX6@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF4044) - - - - - - - - - - - - DUF4044 NAGPHGKN_00321 568703.LGG_01274 0.0 934.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F542@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N NAGPHGKN_00322 568703.LGG_00761 2.17e-265 726.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,3F44N@33958|Lactobacillaceae 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH NAGPHGKN_00323 568703.LGG_00762 1.54e-305 834.0 COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli,3F41P@33958|Lactobacillaceae 91061|Bacilli K DRTGG domain ytoI - - - - - - - - - - - 4HBT,CBS,DRTGG,GntR,HTH_24 NAGPHGKN_00324 568703.LGG_00763 3.53e-228 628.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F4FC@33958|Lactobacillaceae 91061|Bacilli S DHHA1 domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 NAGPHGKN_00325 568703.LGG_00764 1.52e-131 384.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,3F4FQ@33958|Lactobacillaceae 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C NAGPHGKN_00326 568703.LGG_00764 5.68e-162 462.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,3F4FQ@33958|Lactobacillaceae 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C NAGPHGKN_00327 568703.LGG_00765 4.08e-219 605.0 295Z0@1|root,2ZT9T@2|Bacteria,1UJCK@1239|Firmicutes,4IT5A@91061|Bacilli,3F63F@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00328 1423816.BACQ01000077_gene2640 1.2e-07 56.2 COG1105@1|root,COG1105@2|Bacteria,1TR9H@1239|Firmicutes,4HAGR@91061|Bacilli 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily lacC - 2.7.1.144 ko:K00917 ko00052,ko01100,map00052,map01100 - R03236 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB NAGPHGKN_00329 568703.LGG_00767 0.0 1725.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,3F3QS@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD NAGPHGKN_00330 568703.LGG_00768 9.14e-259 709.0 29P5T@1|root,30A3Y@2|Bacteria,1U65R@1239|Firmicutes,4IFVK@91061|Bacilli,3F74N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00331 1423732.BALS01000001_gene1354 4.89e-58 179.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,3F7EG@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 NAGPHGKN_00332 568703.LGG_00770 3.12e-95 278.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,3F6NI@33958|Lactobacillaceae 91061|Bacilli J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX NAGPHGKN_00333 568703.LGG_00771 1.85e-69 209.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,3F6X3@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 NAGPHGKN_00334 568703.LGG_00772 3.45e-49 156.0 COG3027@1|root,COG3027@2|Bacteria,1VFZS@1239|Firmicutes,4HP4T@91061|Bacilli,3F7ZA@33958|Lactobacillaceae 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division - - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA NAGPHGKN_00335 568703.LGG_00773 7.74e-121 345.0 COG1286@1|root,COG1286@2|Bacteria,1V7U0@1239|Firmicutes,4HIUU@91061|Bacilli,3F6FV@33958|Lactobacillaceae 91061|Bacilli S Colicin V production protein cvpA - - - - - - - - - - - Colicin_V NAGPHGKN_00336 568703.LGG_00774 0.0 1498.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,3F4DX@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr NAGPHGKN_00337 568703.LGG_00775 3.64e-70 211.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F6Y3@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin NAGPHGKN_00338 568703.LGG_00777 0.0 1008.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,3F49R@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - AMP-binding,AMP-binding_C NAGPHGKN_00339 568703.LGG_00778 1.46e-305 831.0 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,3F4KK@33958|Lactobacillaceae 91061|Bacilli M MBOAT, membrane-bound O-acyltransferase family dltB - - ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - MBOAT NAGPHGKN_00340 568703.LGG_00779 1.2e-49 157.0 COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli,3F7Q1@33958|Lactobacillaceae 91061|Bacilli J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding NAGPHGKN_00341 568703.LGG_00780 5.21e-315 857.0 COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli,3F3WE@33958|Lactobacillaceae 91061|Bacilli M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) dltD - - ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - DltD NAGPHGKN_00342 568703.LGG_00781 1.18e-109 315.0 COG1719@1|root,COG1719@2|Bacteria,1VD7N@1239|Firmicutes,4HKV3@91061|Bacilli,3F7ZI@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2507) yslB - - - - - - - - - - - DUF2507 NAGPHGKN_00343 568703.LGG_00782 0.0 955.0 COG0127@1|root,COG0796@1|root,COG0127@2|Bacteria,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli,3F446@33958|Lactobacillaceae 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race NAGPHGKN_00344 568703.LGG_00783 2.24e-123 351.0 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli,3F73R@33958|Lactobacillaceae 91061|Bacilli S Phosphoesterase ysnB GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K07095 - - - - ko00000 - - - Metallophos_2 NAGPHGKN_00345 568703.LGG_00784 7.42e-172 479.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HE39@91061|Bacilli,3FCCB@33958|Lactobacillaceae 91061|Bacilli U Major intrinsic protein gla - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP NAGPHGKN_00346 568703.LGG_00785 3.12e-110 317.0 COG0517@1|root,COG0517@2|Bacteria,1VFAB@1239|Firmicutes,4HRWJ@91061|Bacilli,3FBMW@33958|Lactobacillaceae 91061|Bacilli S CBS domain ykuL - - - - - - - - - - - CBS NAGPHGKN_00347 568703.LGG_00786 1.97e-200 556.0 COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,4HBE3@91061|Bacilli,3F4QH@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF368) - - - ko:K08974 - - - - ko00000 - - - DUF368 NAGPHGKN_00348 568703.LGG_00787 5.04e-200 555.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,3F49U@33958|Lactobacillaceae 91061|Bacilli M mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel NAGPHGKN_00350 568703.LGG_00789 7.19e-40 137.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,3F6KB@33958|Lactobacillaceae 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 NAGPHGKN_00351 568703.LGG_00790 8.13e-104 301.0 COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,3F8GC@33958|Lactobacillaceae 91061|Bacilli S YtxH-like protein ytxH - - - - - - - - - - - YtxH NAGPHGKN_00352 568703.LGG_00791 1.83e-119 342.0 COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli,3F7V1@33958|Lactobacillaceae 91061|Bacilli S 3H domain yrxA - - ko:K07105 - - - - ko00000 - - - 3H,HTH_11 NAGPHGKN_00353 568703.LGG_00792 2.2e-274 749.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,3F3X5@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 NAGPHGKN_00354 568703.LGG_00793 6.12e-232 639.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,3F4AA@33958|Lactobacillaceae 91061|Bacilli K catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 NAGPHGKN_00355 568703.LGG_00794 0.0 1636.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F4ZE@33958|Lactobacillaceae 91061|Bacilli M Penicillin binding protein transpeptidase domain pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase NAGPHGKN_00356 1423732.BALS01000048_gene2577 3.18e-07 54.7 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS NAGPHGKN_00357 568703.LGG_00796 1.24e-162 455.0 COG1011@1|root,COG1011@2|Bacteria,1TRQ6@1239|Firmicutes,4HKAS@91061|Bacilli,3FBG9@33958|Lactobacillaceae 91061|Bacilli S HAD-hyrolase-like yfnB - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 NAGPHGKN_00358 568703.LGG_00797 2.39e-173 484.0 COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,3F5HY@33958|Lactobacillaceae 91061|Bacilli H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 NAGPHGKN_00359 568703.LGG_00798 0.0 936.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,3F3UV@33958|Lactobacillaceae 91061|Bacilli E dipeptidase PepV pepV - 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 NAGPHGKN_00360 568703.LGG_00799 0.0 882.0 COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,3FC1S@33958|Lactobacillaceae 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD NAGPHGKN_00361 568703.LGG_00800 3.48e-73 219.0 2C26E@1|root,3424N@2|Bacteria,1VX4A@1239|Firmicutes,4HXT9@91061|Bacilli,3F70Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00362 568703.LGG_00801 4.19e-228 631.0 COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,4HCP3@91061|Bacilli,3F3M9@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibE - - - - - - - - - - - YibE_F NAGPHGKN_00363 568703.LGG_00802 2.41e-153 433.0 COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,4HBKX@91061|Bacilli,3F3S6@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibF - - - - - - - - - - - YibE_F NAGPHGKN_00364 568703.LGG_00803 1.94e-148 417.0 COG4186@1|root,COG4186@2|Bacteria,1V40Y@1239|Firmicutes,4HH4J@91061|Bacilli,3F4EX@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos,Metallophos_2 NAGPHGKN_00365 568703.LGG_00804 8.64e-26 104.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,3F4ZD@33958|Lactobacillaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos NAGPHGKN_00366 568703.LGG_00804 6.72e-297 811.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,3F4ZD@33958|Lactobacillaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos NAGPHGKN_00367 568703.LGG_00805 4.04e-142 401.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli,3F66P@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1027) yutD - - - - - - - - - - - DUF1027 NAGPHGKN_00368 568703.LGG_00806 4.68e-187 519.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,3F49D@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like NAGPHGKN_00369 568703.LGG_00807 8.78e-150 421.0 COG4478@1|root,COG4478@2|Bacteria,1V7UW@1239|Firmicutes,4HHH4@91061|Bacilli,3F4YP@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1461) - - - - - - - - - - - - DUF1461 NAGPHGKN_00370 568703.LGG_00808 4.31e-149 420.0 COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,4HG3F@91061|Bacilli,3F4KG@33958|Lactobacillaceae 91061|Bacilli S SNARE-like domain protein dedA - - ko:K03975 - - - - ko00000 - - - SNARE_assoc NAGPHGKN_00371 568703.LGG_00809 6.48e-115 329.0 COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,3F6QT@33958|Lactobacillaceae 91061|Bacilli I Phosphatidylglycerophosphatase A pgpA - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA NAGPHGKN_00372 568703.LGG_00810 9.5e-238 653.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,3F3NQ@33958|Lactobacillaceae 91061|Bacilli C Ferredoxin--NADP reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 NAGPHGKN_00373 568703.LGG_00811 5.16e-141 397.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,3F3TI@33958|Lactobacillaceae 91061|Bacilli G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Hydrolase_3,Pro_isomerase NAGPHGKN_00374 568703.LGG_00812 2.02e-83 246.0 COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli,3F6AN@33958|Lactobacillaceae 91061|Bacilli J general stress protein yugI - - ko:K07570 - - - - ko00000 - - - S1 NAGPHGKN_00375 568703.LGG_02304 3.78e-248 682.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HA6Y@91061|Bacilli,3FB4B@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE NAGPHGKN_00377 568703.LGG_02303 7.19e-209 579.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F6SN@33958|Lactobacillaceae 91061|Bacilli M UbiA prenyltransferase family menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA NAGPHGKN_00378 568703.LGG_02302 2.18e-218 603.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F3JM@33958|Lactobacillaceae 91061|Bacilli H 1,4-dihydroxy-2-naphthoate ubiA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA NAGPHGKN_00379 568703.LGG_02301 3.75e-30 106.0 COG0267@1|root,COG0267@2|Bacteria,1VFTQ@1239|Firmicutes,4HR5Q@91061|Bacilli,3F83F@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 NAGPHGKN_00380 568703.LGG_02300 2.53e-31 109.0 COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4HR1W@91061|Bacilli,3F86Y@33958|Lactobacillaceae 91061|Bacilli U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE NAGPHGKN_00381 568703.LGG_02299 8e-131 371.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,3F55W@33958|Lactobacillaceae 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG NAGPHGKN_00382 568703.LGG_02298 1.64e-203 563.0 COG4814@1|root,COG4814@2|Bacteria,1V910@1239|Firmicutes,4HF90@91061|Bacilli,3F4RX@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 NAGPHGKN_00383 568703.LGG_02297 6.51e-103 297.0 COG3613@1|root,COG3613@2|Bacteria,1VETR@1239|Firmicutes,4HNTN@91061|Bacilli,3F6C3@33958|Lactobacillaceae 91061|Bacilli F nucleoside 2-deoxyribosyltransferase - - 2.4.2.6 ko:K08728 ko00240,map00240 - R02806 RC00063 ko00000,ko00001,ko01000 - - - Nuc_deoxyrib_tr NAGPHGKN_00384 568703.LGG_02296 0.0 1519.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,4HFF1@91061|Bacilli,3F3VU@33958|Lactobacillaceae 91061|Bacilli F ribonucleoside-triphosphate reductase activity rtpR - 1.17.4.2 ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02014,R02020,R02022,R02023,R04315 RC00013,RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC NAGPHGKN_00385 568703.LGG_02295 2.89e-82 244.0 2DNM7@1|root,32Y2X@2|Bacteria,1VF26@1239|Firmicutes,4HP82@91061|Bacilli,3F6AM@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4430) - - - - - - - - - - - - DUF4430 NAGPHGKN_00386 568703.LGG_02294 5.8e-113 325.0 COG4720@1|root,COG4720@2|Bacteria,1V5GD@1239|Firmicutes,4HI8Y@91061|Bacilli,3F5H7@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF-ribofla_trS,ECF_trnsprt NAGPHGKN_00387 568703.LGG_02293 5.42e-117 335.0 COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,4IS1C@91061|Bacilli,3FBQY@33958|Lactobacillaceae 91061|Bacilli S Cobalamin adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans NAGPHGKN_00388 568703.LGG_02292 0.0 923.0 COG0154@1|root,COG0154@2|Bacteria,1TPGJ@1239|Firmicutes,4HBE7@91061|Bacilli,3F4UM@33958|Lactobacillaceae 91061|Bacilli J Belongs to the amidase family nylA - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase,Gram_pos_anchor NAGPHGKN_00389 568703.LGG_02290 0.0 1687.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HBQJ@91061|Bacilli,3F4E0@33958|Lactobacillaceae 91061|Bacilli P COG0474 Cation transport ATPase mgtA - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase NAGPHGKN_00390 568703.LGG_02289 1.97e-92 270.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,3F64I@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N NAGPHGKN_00391 568703.LGG_02288 1.33e-158 445.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,3F3VQ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 NAGPHGKN_00392 568703.LGG_02287 4.45e-122 348.0 COG3981@1|root,COG3981@2|Bacteria,1VEFC@1239|Firmicutes,4HQJP@91061|Bacilli,3F8WP@33958|Lactobacillaceae 91061|Bacilli S Acetyltransferase (GNAT) domain yqaB - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3 NAGPHGKN_00393 568703.LGG_02286 3.3e-228 635.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh NAGPHGKN_00394 568703.LGG_02286 4.16e-65 210.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh NAGPHGKN_00395 568703.LGG_02285 0.0 1038.0 COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli,3F4P6@33958|Lactobacillaceae 91061|Bacilli M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon tagE GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Asp1,Glyco_trans_A_1,Glycos_transf_1 NAGPHGKN_00396 568703.LGG_02284 0.0 994.0 COG0438@1|root,COG0438@2|Bacteria,1UY71@1239|Firmicutes,4HFBM@91061|Bacilli,3FC1Q@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Glycos_transf_1 NAGPHGKN_00397 568703.LGG_02282 0.0 933.0 2DE74@1|root,2ZKT0@2|Bacteria,1W5A1@1239|Firmicutes,4I0IZ@91061|Bacilli,3F4Z4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00399 568703.LGG_02281 1.03e-281 771.0 COG2271@1|root,COG2271@2|Bacteria,1UHSG@1239|Firmicutes,4IS86@91061|Bacilli,3FBXF@33958|Lactobacillaceae 91061|Bacilli G Sugar (and other) transporter yceI - - ko:K08369 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr NAGPHGKN_00400 568703.LGG_02280 2.4e-117 336.0 29Q17@1|root,30AZR@2|Bacteria,1U7BG@1239|Firmicutes,4IH6H@91061|Bacilli,3F99Z@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00401 568703.LGG_02279 5.9e-193 535.0 COG0454@1|root,COG0456@2|Bacteria,1V42X@1239|Firmicutes,4HI1M@91061|Bacilli,3F6TI@33958|Lactobacillaceae 91061|Bacilli K acetyltransferase - - - - - - - - - - - - - NAGPHGKN_00402 568703.LGG_02278 8.53e-287 784.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,3F3T5@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein mdtG - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr NAGPHGKN_00403 568703.LGG_02277 6.19e-109 314.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,3F4S4@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 NAGPHGKN_00404 1423816.BACQ01000053_gene2056 4.57e-73 220.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,3F6YA@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N NAGPHGKN_00405 568703.LGG_02275 1.62e-199 554.0 COG0760@1|root,COG0760@2|Bacteria,1VT0K@1239|Firmicutes,4I4BP@91061|Bacilli,3F4RW@33958|Lactobacillaceae 91061|Bacilli M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins - - 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 NAGPHGKN_00406 568703.LGG_02274 0.0 3440.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,3F3M5@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase S8 family prtB - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLAP,fn3_5 NAGPHGKN_00407 568703.LGG_02273 1.22e-220 608.0 COG1609@1|root,COG1609@2|Bacteria,1TQSQ@1239|Firmicutes,4HBNR@91061|Bacilli,3F4YI@33958|Lactobacillaceae 91061|Bacilli K lacI family ccpB - - - - - - - - - - - LacI,Peripla_BP_1 NAGPHGKN_00408 568703.LGG_02272 7.81e-88 258.0 2BJY6@1|root,32EAT@2|Bacteria,1U7NB@1239|Firmicutes,4IHJK@91061|Bacilli,3F9XZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00409 568703.LGG_00728 1.6e-114 328.0 COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,3F5VY@33958|Lactobacillaceae 91061|Bacilli O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin NAGPHGKN_00410 568703.LGG_00729 2.95e-123 351.0 29FTP@1|root,302RC@2|Bacteria,1TTTN@1239|Firmicutes,4IHGE@91061|Bacilli,3F9TG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00411 568703.LGG_00730 6.46e-218 603.0 COG1396@1|root,COG1396@2|Bacteria,1W1BY@1239|Firmicutes,4HY3Y@91061|Bacilli,3F71S@33958|Lactobacillaceae 91061|Bacilli K sequence-specific DNA binding - - - - - - - - - - - - HTH_19 NAGPHGKN_00412 568703.LGG_00731 0.0 975.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HIAU@91061|Bacilli,3F3JJ@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran NAGPHGKN_00413 568703.LGG_00732 0.0 1188.0 COG1164@1|root,COG1164@2|Bacteria,1TR7D@1239|Firmicutes,4HA0P@91061|Bacilli,3F3R3@33958|Lactobacillaceae 91061|Bacilli E Oligopeptidase F pepF - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N NAGPHGKN_00414 568703.LGG_00733 2.01e-102 296.0 COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,3F68C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the NDK family ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK NAGPHGKN_00415 568703.LGG_00734 1.05e-71 216.0 29Q7J@1|root,30B6K@2|Bacteria,1U7MR@1239|Firmicutes,4IHIY@91061|Bacilli,3F9X3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00416 568703.LGG_00735 0.0 949.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9ZI@91061|Bacilli,3F4Y1@33958|Lactobacillaceae 91061|Bacilli P E1-E2 ATPase yfgQ - - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase NAGPHGKN_00417 568703.LGG_00735 8.94e-157 462.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9ZI@91061|Bacilli,3F4Y1@33958|Lactobacillaceae 91061|Bacilli P E1-E2 ATPase yfgQ - - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase NAGPHGKN_00418 568703.LGG_00736 3.53e-227 625.0 COG2267@1|root,COG2267@2|Bacteria,1U46X@1239|Firmicutes,4IDYA@91061|Bacilli,3F5WU@33958|Lactobacillaceae 91061|Bacilli I Releases the N-terminal proline from various substrates - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 NAGPHGKN_00419 568703.LGG_00737 1.03e-77 231.0 29Q8P@1|root,30B7R@2|Bacteria,1U7PN@1239|Firmicutes,4IHKZ@91061|Bacilli,3F9ZK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00420 568703.LGG_00738 2.66e-119 347.0 COG1670@1|root,COG1670@2|Bacteria,1UM04@1239|Firmicutes,4ITN9@91061|Bacilli,3FBX6@33958|Lactobacillaceae 91061|Bacilli J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - - NAGPHGKN_00421 568703.LGG_00739 2.39e-257 707.0 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,3F3QK@33958|Lactobacillaceae 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family napA - - - - - - - - - - - Na_H_Exchanger NAGPHGKN_00422 568703.LGG_00740 5.26e-155 435.0 COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,4HQUJ@91061|Bacilli,3FCA0@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase XK27_05175 - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 NAGPHGKN_00423 568703.LGG_00741 6.42e-101 293.0 COG1846@1|root,COG1846@2|Bacteria,1V6TR@1239|Firmicutes,4HXA8@91061|Bacilli,3F66M@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 NAGPHGKN_00424 568703.LGG_00742 2.81e-230 633.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,FSH1,Hydrolase_4 NAGPHGKN_00425 568703.LGG_00743 2.14e-110 317.0 COG1780@1|root,COG1780@2|Bacteria,1V71V@1239|Firmicutes,4HIW7@91061|Bacilli,3F6JF@33958|Lactobacillaceae 91061|Bacilli F Belongs to the NrdI family nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI NAGPHGKN_00426 568703.LGG_00744 1.3e-201 557.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HACK@91061|Bacilli,3F4XF@33958|Lactobacillaceae 91061|Bacilli S reductase dkgB - - - - - - - - - - - Aldo_ket_red NAGPHGKN_00427 568703.LGG_00745 1.84e-161 454.0 29Q1I@1|root,30B03@2|Bacteria,1U7BX@1239|Firmicutes,4IH77@91061|Bacilli,3F9BB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00428 568703.LGG_00746 9.91e-205 566.0 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 NAGPHGKN_00429 568703.LGG_00747 4.32e-148 417.0 COG2323@1|root,COG2323@2|Bacteria,1TPNF@1239|Firmicutes,4HF15@91061|Bacilli,3F4F3@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF421) yviA - - - - - - - - - - - DUF421 NAGPHGKN_00430 568703.LGG_00748 5.25e-96 280.0 2C9NT@1|root,32ZGB@2|Bacteria,1VG8C@1239|Firmicutes,4HN0V@91061|Bacilli,3F749@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3290) - - - - - - - - - - - - DUF3290 NAGPHGKN_00431 568703.LGG_00749 3.84e-280 764.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,3F49P@33958|Lactobacillaceae 91061|Bacilli E methionine synthase, vitamin-B12 independent metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 NAGPHGKN_00432 568703.LGG_00750 1.19e-112 323.0 COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,3F4W2@33958|Lactobacillaceae 91061|Bacilli H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS NAGPHGKN_00433 568703.LGG_00751 1.25e-134 382.0 COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,4HJDU@91061|Bacilli,3FCEX@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein yjbF - - - - - - - - - - - SNARE_assoc NAGPHGKN_00434 568703.LGG_00752 2.42e-132 376.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,3F42W@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N NAGPHGKN_00435 568703.LGG_00753 4.98e-250 686.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,3F47S@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N NAGPHGKN_00436 568703.LGG_00754 7.58e-264 722.0 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,3F3VG@33958|Lactobacillaceae 91061|Bacilli J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth NAGPHGKN_00437 568703.LGG_00755 6.98e-289 787.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,3F43F@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT NAGPHGKN_00438 568703.LGG_00756 2.9e-85 252.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,3F7EY@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC NAGPHGKN_00439 568703.LGG_00757 0.0 1706.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli,3F3RN@33958|Lactobacillaceae 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH NAGPHGKN_00440 568703.LGG_00759 1.45e-150 423.0 COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HI7T@91061|Bacilli,3FBMJ@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix diphteria tox regulatory element mntR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA NAGPHGKN_00441 568703.LGG_00760 0.0 995.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,3F48G@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N NAGPHGKN_00442 568703.LGG_02085 2.56e-126 361.0 29Q1U@1|root,30B0E@2|Bacteria,1U7CC@1239|Firmicutes,4IH7Q@91061|Bacilli,3F9CG@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL NAGPHGKN_00443 568703.LGG_02086 1.38e-185 516.0 COG0524@1|root,COG0524@2|Bacteria,1TSST@1239|Firmicutes,4HGU3@91061|Bacilli,3F7U3@33958|Lactobacillaceae 91061|Bacilli G pfkB family carbohydrate kinase frlD1 - 2.7.1.218 ko:K10710 - - R08124 RC00002,RC00017 ko00000,ko01000 - - - PfkB NAGPHGKN_00444 568703.LGG_02087 2.51e-129 410.0 COG1409@1|root,COG4632@1|root,COG1409@2|Bacteria,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,4HDPI@91061|Bacilli 91061|Bacilli G Phosphodiester glycosidase - - - - - - - - - - - - Metallophos,NAGPA,Pur_ac_phosph_N NAGPHGKN_00445 568703.LGG_02087 5.03e-180 555.0 COG1409@1|root,COG4632@1|root,COG1409@2|Bacteria,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,4HDPI@91061|Bacilli 91061|Bacilli G Phosphodiester glycosidase - - - - - - - - - - - - Metallophos,NAGPA,Pur_ac_phosph_N NAGPHGKN_00446 568703.LGG_02088 0.0 994.0 COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,4HB8X@91061|Bacilli,3F4TR@33958|Lactobacillaceae 91061|Bacilli EQ Hydantoinase/oxoprolinase N-terminal region hyuA - - - - - - - - - - - Hydant_A_N,Hydantoinase_A NAGPHGKN_00447 568703.LGG_02089 9.89e-264 722.0 COG3535@1|root,COG3535@2|Bacteria,1TR39@1239|Firmicutes,4HC1C@91061|Bacilli,3F5F2@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF917) - - - ko:K09703 - - - - ko00000 - - - DUF917 NAGPHGKN_00448 568703.LGG_02090 8.08e-282 772.0 COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,4HD25@91061|Bacilli 91061|Bacilli F Permease for cytosine/purines, uracil, thiamine, allantoin - - - ko:K10974 - - - - ko00000,ko02000 2.A.39.1 - - Transp_cyt_pur NAGPHGKN_00449 568703.LGG_02091 3.27e-167 470.0 29Q4F@1|root,30B35@2|Bacteria,1U7G9@1239|Firmicutes,4IHCF@91061|Bacilli,3F9KY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00450 568703.LGG_02092 3.42e-126 377.0 COG1479@1|root,COG1479@2|Bacteria,1TPAT@1239|Firmicutes,4HPJ0@91061|Bacilli,3FB8C@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1524) - - - - - - - - - - - - DUF1524,DUF262 NAGPHGKN_00451 568703.LGG_02092 6.06e-256 716.0 COG1479@1|root,COG1479@2|Bacteria,1TPAT@1239|Firmicutes,4HPJ0@91061|Bacilli,3FB8C@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1524) - - - - - - - - - - - - DUF1524,DUF262 NAGPHGKN_00452 568703.LGG_02093 0.0 1340.0 COG4930@1|root,COG4930@2|Bacteria,1TRIB@1239|Firmicutes,4HB8U@91061|Bacilli,3F5IN@33958|Lactobacillaceae 91061|Bacilli O Putative ATP-dependent Lon protease - - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - Lon_2,Lon_C NAGPHGKN_00453 568703.LGG_02094 0.0 1655.0 COG1524@1|root,COG1524@2|Bacteria,1TP12@1239|Firmicutes,4HEFH@91061|Bacilli,3F4VN@33958|Lactobacillaceae 91061|Bacilli S PglZ domain - - - - - - - - - - - - PglZ NAGPHGKN_00454 568703.LGG_00831 1.8e-104 301.0 COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli,3F67J@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Fur family perR - - ko:K03711,ko:K09825 - - - - ko00000,ko03000 - - - FUR NAGPHGKN_00455 568703.LGG_00830 0.0 1334.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase NAGPHGKN_00456 568703.LGG_00829 1.4e-58 181.0 COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli,3F82V@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1797) ykuJ - - - - - - - - - - - DUF1797 NAGPHGKN_00457 568703.LGG_00828 6.38e-229 634.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase araT - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 NAGPHGKN_00458 568703.LGG_00827 4.38e-222 614.0 COG0392@1|root,COG0392@2|Bacteria,1UY7Z@1239|Firmicutes,4HCG6@91061|Bacilli,3F3UR@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM NAGPHGKN_00459 568703.LGG_00826 2.69e-65 207.0 COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HB9F@91061|Bacilli,3F47X@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 2.4.1.208 ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 - R05164,R10865 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 NAGPHGKN_00460 568703.LGG_00826 7.61e-103 308.0 COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HB9F@91061|Bacilli,3F47X@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 2.4.1.208 ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 - R05164,R10865 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 NAGPHGKN_00461 568703.LGG_00825 6.32e-294 801.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli,3F4H5@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein pimB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 NAGPHGKN_00462 568703.LGG_00824 0.0 1033.0 COG0531@1|root,COG0531@2|Bacteria,1TPJH@1239|Firmicutes,4HC13@91061|Bacilli,3F4AR@33958|Lactobacillaceae 91061|Bacilli E amino acid ybeC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 NAGPHGKN_00463 568703.LGG_00823 5.22e-120 343.0 COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,4HAHR@91061|Bacilli,3FBRS@33958|Lactobacillaceae 91061|Bacilli K Sigma-70 region 2 sigH - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 NAGPHGKN_00472 568703.LGG_01898 1.97e-168 470.0 COG3527@1|root,COG3527@2|Bacteria,1V4AH@1239|Firmicutes,4HJ98@91061|Bacilli,3FCCX@33958|Lactobacillaceae 91061|Bacilli Q Alpha-acetolactate decarboxylase budA - 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy NAGPHGKN_00474 568703.LGG_01896 0.0 922.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,3F4BG@33958|Lactobacillaceae 91061|Bacilli E amino acid lysP - - ko:K03293,ko:K11733 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.2 - - AA_permease NAGPHGKN_00475 568703.LGG_01895 0.0 1023.0 COG3711@1|root,COG3711@2|Bacteria,1VVKT@1239|Firmicutes,4HWA8@91061|Bacilli,3F48X@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - Mga NAGPHGKN_00476 568703.LGG_01894 0.0 1035.0 COG3711@1|root,COG3711@2|Bacteria,1VVKT@1239|Firmicutes,4HWA8@91061|Bacilli,3F5TE@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - Mga NAGPHGKN_00477 568703.LGG_01893 5.08e-283 776.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,3F3M6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b NAGPHGKN_00478 568703.LGG_02508 0.0 929.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,3F439@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon NAGPHGKN_00479 568703.LGG_02509 1.12e-243 669.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,3F4C6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus NAGPHGKN_00480 568703.LGG_02510 4.9e-207 573.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,3F42B@33958|Lactobacillaceae 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 NAGPHGKN_00481 568703.LGG_02514 0.0 1330.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,3F49Z@33958|Lactobacillaceae 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 NAGPHGKN_00482 568703.LGG_02515 2.04e-125 357.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,3F56C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran NAGPHGKN_00483 568703.LGG_02516 9.66e-308 839.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,3F4GY@33958|Lactobacillaceae 91061|Bacilli J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C NAGPHGKN_00484 568703.LGG_02517 8.3e-105 303.0 COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,3F6HV@33958|Lactobacillaceae 91061|Bacilli J RNA binding yabR - - ko:K07571 - - - - ko00000 - - - S1 NAGPHGKN_00485 568703.LGG_02518 1.87e-84 249.0 COG2919@1|root,COG2919@2|Bacteria 2|Bacteria D cell cycle divIC - - ko:K05589,ko:K13052 - - - - ko00000,ko03036 - - - DivIC NAGPHGKN_00486 568703.LGG_02519 2.33e-52 165.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,3F7JX@33958|Lactobacillaceae 91061|Bacilli J S4 domain protein yabO - - - - - - - - - - - S4 NAGPHGKN_00487 568703.LGG_02520 0.0 968.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HACG@91061|Bacilli,3F4BV@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C NAGPHGKN_00488 568703.LGG_02521 0.0 2264.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,3F4KU@33958|Lactobacillaceae 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF NAGPHGKN_00489 568703.LGG_02522 1.05e-131 373.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,3F3VZ@33958|Lactobacillaceae 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro NAGPHGKN_00490 543734.LCABL_27160 5.04e-232 639.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F3RM@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N NAGPHGKN_00491 568703.LGG_02524 0.0 922.0 COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,4HDTN@91061|Bacilli,3F3QW@33958|Lactobacillaceae 91061|Bacilli S Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_4,YkuD NAGPHGKN_00492 568703.LGG_02525 2.6e-124 354.0 COG1695@1|root,COG1695@2|Bacteria,1VC8Z@1239|Firmicutes,4HKXU@91061|Bacilli,3F7RS@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family padR - - - - - - - - - - - PadR,Vir_act_alpha_C NAGPHGKN_00493 568703.LGG_02526 0.0 893.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,3F46P@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 NAGPHGKN_00494 568703.LGG_02527 3.35e-148 416.0 COG2249@1|root,COG2249@2|Bacteria,1VB36@1239|Firmicutes,4HW64@91061|Bacilli,3F66F@33958|Lactobacillaceae 91061|Bacilli S Flavodoxin-like fold - - - - - - - - - - - - Flavodoxin_2 NAGPHGKN_00495 568703.LGG_02528 1.9e-154 434.0 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,3F3JY@33958|Lactobacillaceae 91061|Bacilli S (CBS) domain - - - - - - - - - - - - CBS NAGPHGKN_00496 568703.LGG_02529 1.69e-167 468.0 COG1376@1|root,COG1376@2|Bacteria,1V4KP@1239|Firmicutes,4HIBF@91061|Bacilli,3F6PH@33958|Lactobacillaceae 91061|Bacilli M ErfK YbiS YcfS YnhG yciB - - - - - - - - - - - YkuD NAGPHGKN_00497 568703.LGG_02530 0.0 961.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4HAD5@91061|Bacilli,3FB6A@33958|Lactobacillaceae 91061|Bacilli E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iSB619.SA_RS02450 Fer4_20,Pyr_redox_2 NAGPHGKN_00498 568703.LGG_02531 0.0 2940.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,3F4TU@33958|Lactobacillaceae 91061|Bacilli E GXGXG motif gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase NAGPHGKN_00499 568703.LGG_02532 1.33e-111 322.0 COG4708@1|root,COG4708@2|Bacteria,1V463@1239|Firmicutes,4HH0P@91061|Bacilli,3FCEF@33958|Lactobacillaceae 91061|Bacilli S QueT transporter queT - - - - - - - - - - - QueT NAGPHGKN_00500 1423732.BALS01000035_gene242 2.32e-82 244.0 COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,4HGXF@91061|Bacilli,3F6Y9@33958|Lactobacillaceae 91061|Bacilli L Toxic component of a toxin-antitoxin (TA) module ndoA - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin NAGPHGKN_00501 568703.LGG_02535 5.46e-51 161.0 29PVB@1|root,30ATJ@2|Bacteria,1U736@1239|Firmicutes,4IGXQ@91061|Bacilli,3F8WZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00502 568703.LGG_02536 2.9e-276 755.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,3F3X2@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N NAGPHGKN_00503 568703.LGG_02537 2.25e-83 246.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,3F6HC@33958|Lactobacillaceae 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS NAGPHGKN_00504 568703.LGG_02538 0.0 955.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,3F46Q@33958|Lactobacillaceae 91061|Bacilli F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C NAGPHGKN_00505 568703.LGG_02539 0.0 900.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,3F4SK@33958|Lactobacillaceae 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M NAGPHGKN_00506 568703.LGG_02540 1.77e-189 525.0 29SV9@1|root,30E1E@2|Bacteria,1V46E@1239|Firmicutes,4HI7R@91061|Bacilli,3F6E2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00507 568703.LGG_02541 1.11e-158 444.0 COG0457@1|root,COG0457@2|Bacteria,1VQ45@1239|Firmicutes,4HRFF@91061|Bacilli,3F62R@33958|Lactobacillaceae 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - SUKH_6 NAGPHGKN_00508 568703.LGG_02542 4.49e-159 446.0 2DNW7@1|root,32ZGM@2|Bacteria,1V8QF@1239|Firmicutes,4HIIB@91061|Bacilli,3F601@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00509 568703.LGG_02543 2.69e-95 278.0 29Q2X@1|root,30B1I@2|Bacteria,1U7DP@1239|Firmicutes,4IH9K@91061|Bacilli,3F9FK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00510 568703.LGG_02544 3.24e-57 177.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HKF0@91061|Bacilli,3F7D7@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L31 rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 NAGPHGKN_00511 568703.LGG_02545 3.31e-300 819.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,3F3P8@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase NAGPHGKN_00513 568703.LGG_02546 0.0 1067.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,3F42X@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase NAGPHGKN_00514 568703.LGG_02547 2.23e-279 764.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,3F4N1@33958|Lactobacillaceae 91061|Bacilli C NADH dehydrogenase yumB GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU32100 Pyr_redox_2 NAGPHGKN_00517 568703.LGG_02550 4.99e-194 540.0 COG3548@1|root,COG3548@2|Bacteria,1VNI3@1239|Firmicutes,4HSHZ@91061|Bacilli,3F5J9@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) ybbB - - - - - - - - - - - DUF1211 NAGPHGKN_00518 1423816.BACQ01000037_gene1576 3.09e-103 305.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,3F55D@33958|Lactobacillaceae 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE - - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH NAGPHGKN_00519 568703.LGG_02552 1.21e-103 299.0 COG4506@1|root,COG4506@2|Bacteria,1V8IZ@1239|Firmicutes,4HIW0@91061|Bacilli,3F6AI@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1934) ywiB - - - - - - - - - - - DUF1934 NAGPHGKN_00520 568703.LGG_02554 2.07e-202 560.0 COG0095@1|root,COG0095@2|Bacteria,1TQKA@1239|Firmicutes,4HCPS@91061|Bacilli,3F575@33958|Lactobacillaceae 91061|Bacilli H biotin lipoate A B protein ligase lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 - - - - ko00000,ko01000 - - - BPL_LplA_LipB NAGPHGKN_00521 568703.LGG_02555 0.0 912.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,3F442@33958|Lactobacillaceae 91061|Bacilli S HD domain protein ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD NAGPHGKN_00522 568703.LGG_02556 1.53e-107 309.0 COG0494@1|root,COG0494@2|Bacteria,1VD6I@1239|Firmicutes,4HKRW@91061|Bacilli,3F75N@33958|Lactobacillaceae 91061|Bacilli L NUDIX domain mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX NAGPHGKN_00523 568703.LGG_02557 3.18e-239 659.0 COG1434@1|root,COG1434@2|Bacteria,1UR34@1239|Firmicutes,4HDF2@91061|Bacilli,3F4J5@33958|Lactobacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 NAGPHGKN_00524 568703.LGG_02558 1.4e-78 234.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,3F6YZ@33958|Lactobacillaceae 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL NAGPHGKN_00525 568703.LGG_02559 1.16e-95 279.0 29Q81@1|root,30B72@2|Bacteria,1U7NH@1239|Firmicutes,4IHJT@91061|Bacilli,3F9YA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00526 568703.LGG_02560 6.37e-67 203.0 COG4043@1|root,COG4043@2|Bacteria,1VEJD@1239|Firmicutes,4HNU5@91061|Bacilli,3F8KY@33958|Lactobacillaceae 91061|Bacilli S ASCH nudA - - - - - - - - - - - ASCH NAGPHGKN_00527 568703.LGG_02561 2.2e-225 622.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3U2@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N NAGPHGKN_00528 568703.LGG_02562 4.27e-295 810.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,3F4I3@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase NAGPHGKN_00529 568703.LGG_02563 1.84e-281 770.0 COG4767@1|root,COG4767@2|Bacteria,1V04Y@1239|Firmicutes,4HDS5@91061|Bacilli,3F3SH@33958|Lactobacillaceae 91061|Bacilli V RDD family ysaA - - - - - - - - - - - RDD,VanZ NAGPHGKN_00530 568703.LGG_02564 1.37e-160 452.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,3F3NH@33958|Lactobacillaceae 91061|Bacilli F pur operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N NAGPHGKN_00531 568703.LGG_02565 1.84e-154 433.0 COG4619@1|root,COG4619@2|Bacteria,1V3DQ@1239|Firmicutes,4HHGU@91061|Bacilli,3F4UY@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ybbL - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran NAGPHGKN_00532 568703.LGG_02566 1.38e-156 442.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,3F4P1@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0014) ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 NAGPHGKN_00533 568703.LGG_02567 6.67e-204 565.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,3F4KJ@33958|Lactobacillaceae 91061|Bacilli P cation diffusion facilitator family transporter czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux NAGPHGKN_00534 568703.LGG_02568 8.83e-209 577.0 COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,3F43W@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.29 - iYO844.BSU00460 GHMP_kinases_C,GHMP_kinases_N NAGPHGKN_00535 568703.LGG_02569 4.13e-51 161.0 COG4466@1|root,COG4466@2|Bacteria,1VEQM@1239|Firmicutes,4HKF8@91061|Bacilli,3F7D3@33958|Lactobacillaceae 91061|Bacilli S Biofilm formation stimulator VEG veg - - - - - - - - - - - VEG NAGPHGKN_00536 568703.LGG_02571 8e-197 547.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,3F3VC@33958|Lactobacillaceae 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD NAGPHGKN_00537 568703.LGG_02572 5.35e-127 362.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,3F64F@33958|Lactobacillaceae 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 NAGPHGKN_00538 568703.LGG_02573 7.18e-187 519.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,3F3N2@33958|Lactobacillaceae 91061|Bacilli L hydrolase, TatD family tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase NAGPHGKN_00539 568703.LGG_02574 7.89e-105 303.0 COG1762@1|root,COG1762@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system manR - 2.7.1.194,2.7.1.200,2.7.1.202 ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00550 R03232,R05570,R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5.1,4.A.7.1 - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB NAGPHGKN_00540 568703.LGG_02575 4.53e-238 654.0 COG3684@1|root,COG3684@2|Bacteria,1TQRR@1239|Firmicutes,4HBS9@91061|Bacilli,3F3UA@33958|Lactobacillaceae 91061|Bacilli G Belongs to the aldolase LacD family lacD - 4.1.2.40 ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 - R01069 RC00438,RC00439 ko00000,ko00001,ko01000 - - - DeoC NAGPHGKN_00541 568703.LGG_02577 1.65e-89 268.0 COG2017@1|root,COG2017@2|Bacteria,1V3WP@1239|Firmicutes,4HHIH@91061|Bacilli,3F5RU@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase yqhA - - - - - - - - - - - Aldose_epim NAGPHGKN_00542 568703.LGG_02577 9.1e-114 331.0 COG2017@1|root,COG2017@2|Bacteria,1V3WP@1239|Firmicutes,4HHIH@91061|Bacilli,3F5RU@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase yqhA - - - - - - - - - - - Aldose_epim NAGPHGKN_00543 568703.LGG_02578 1.23e-161 453.0 COG3279@1|root,COG3279@2|Bacteria,1TRDQ@1239|Firmicutes,4HP0H@91061|Bacilli,3FC2V@33958|Lactobacillaceae 91061|Bacilli T LytTr DNA-binding domain - - - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg NAGPHGKN_00544 568703.LGG_02579 3.2e-212 587.0 COG3290@1|root,COG3290@2|Bacteria,1UZ9P@1239|Firmicutes,4HQIT@91061|Bacilli,3F5Q1@33958|Lactobacillaceae 91061|Bacilli T GHKL domain - - - - - - - - - - - - HATPase_c_5,SPOB_a NAGPHGKN_00545 568703.LGG_02580 0.0 1134.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli,3F604@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_tran NAGPHGKN_00546 568703.LGG_02581 0.0 1206.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli,3F53S@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_tran NAGPHGKN_00547 568703.LGG_02582 3.93e-41 135.0 COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,4HNVM@91061|Bacilli 91061|Bacilli K Transcriptional - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 NAGPHGKN_00548 568703.LGG_02583 3.43e-85 253.0 2A74U@1|root,30W0N@2|Bacteria,1U7RD@1239|Firmicutes,4IHNR@91061|Bacilli,3FA2B@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00549 568703.LGG_02584 0.0 1325.0 COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,3F3XR@33958|Lactobacillaceae 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind NAGPHGKN_00550 568703.LGG_02587 8.68e-220 606.0 COG2267@1|root,COG2267@2|Bacteria,1TRMT@1239|Firmicutes,4HE23@91061|Bacilli,3F40N@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepI - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 NAGPHGKN_00551 568703.LGG_02589 1.35e-193 537.0 COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,4HA0X@91061|Bacilli,3F40Y@33958|Lactobacillaceae 91061|Bacilli F Protein of unknown function DUF72 yunF - - - - - - - - - - - DUF72 NAGPHGKN_00552 568703.LGG_02590 4.46e-118 337.0 COG1051@1|root,COG1051@2|Bacteria,1VAC7@1239|Firmicutes,4HKN6@91061|Bacilli,3F7HC@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX NAGPHGKN_00553 568703.LGG_02591 1.8e-217 600.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli,3F4M2@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily - - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N NAGPHGKN_00554 568703.LGG_02592 3.59e-136 385.0 COG3548@1|root,COG3548@2|Bacteria,1VAQZ@1239|Firmicutes,4HJFH@91061|Bacilli,3F6Q5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) yiiE - - - - - - - - - - - DUF1211 NAGPHGKN_00555 568703.LGG_02593 3.42e-166 464.0 COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HGHS@91061|Bacilli,3FC3Y@33958|Lactobacillaceae 91061|Bacilli K Sir2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 NAGPHGKN_00556 568703.LGG_02595 4.44e-161 455.0 296WI@1|root,2ZU5A@2|Bacteria,1VT7R@1239|Firmicutes,4HVBN@91061|Bacilli,3F4R1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00557 568703.LGG_02596 1.12e-125 357.0 COG1881@1|root,COG1881@2|Bacteria,1VJEE@1239|Firmicutes,4HXTJ@91061|Bacilli,3F75J@33958|Lactobacillaceae 91061|Bacilli S Phosphatidylethanolamine-binding protein yxkA - - ko:K06910 - - - - ko00000 - - - PBP NAGPHGKN_00558 568703.LGG_02597 3.78e-51 162.0 29BUI@1|root,2ZYSU@2|Bacteria,1U6QJ@1239|Firmicutes,4IGHU@91061|Bacilli,3F8B7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00559 568703.LGG_02598 3.46e-219 606.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli,3FBNF@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1002) ypuA - - - - - - - - - - - DUF1002 NAGPHGKN_00560 568703.LGG_02599 1e-220 609.0 COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,3F3SR@33958|Lactobacillaceae 91061|Bacilli FP exopolyphosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA NAGPHGKN_00561 568703.LGG_02600 0.0 1425.0 COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,4HA88@91061|Bacilli,3F3PE@33958|Lactobacillaceae 91061|Bacilli P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N NAGPHGKN_00562 568703.LGG_02601 0.0 983.0 COG0248@1|root,COG0248@2|Bacteria,1VT8Q@1239|Firmicutes,4HB84@91061|Bacilli,3F49N@33958|Lactobacillaceae 91061|Bacilli FP exopolyphosphatase ppx3 - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA NAGPHGKN_00563 568703.LGG_02602 8.29e-223 614.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,3F4U1@33958|Lactobacillaceae 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red NAGPHGKN_00564 568703.LGG_02603 2.94e-198 549.0 COG0500@1|root,COG0500@2|Bacteria,1TT22@1239|Firmicutes,4HBCP@91061|Bacilli,3F99K@33958|Lactobacillaceae 91061|Bacilli Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - Methyltransf_23,Methyltransf_25,PCMT NAGPHGKN_00565 568703.LGG_02604 6.53e-118 337.0 COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,3F70T@33958|Lactobacillaceae 91061|Bacilli M Acetyltransferase (GNAT) domain ywnH GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_3,Acetyltransf_4 NAGPHGKN_00566 568703.LGG_02605 1.3e-302 828.0 COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli,3FC3X@33958|Lactobacillaceae 91061|Bacilli V MatE dinF - - - - - - - - - - - MatE NAGPHGKN_00567 568703.LGG_02607 6.41e-141 405.0 COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4HJVB@91061|Bacilli,3F5HD@33958|Lactobacillaceae 91061|Bacilli S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase NAGPHGKN_00568 568703.LGG_02608 4.87e-134 380.0 COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,4HH6X@91061|Bacilli,3FCF0@33958|Lactobacillaceae 91061|Bacilli S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA NAGPHGKN_00569 568703.LGG_02609 6.02e-246 675.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,3F3V6@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b NAGPHGKN_00570 748671.LCRIS_00116 9.24e-91 286.0 COG0477@1|root,COG2814@2|Bacteria,1UMZG@1239|Firmicutes,4IU42@91061|Bacilli,3F6CJ@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 NAGPHGKN_00571 568703.LGG_02615 0.0 868.0 COG1249@1|root,COG1249@2|Bacteria,1TS0Z@1239|Firmicutes,4HBYB@91061|Bacilli,3F3K2@33958|Lactobacillaceae 91061|Bacilli C Glutathione reductase gshR - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim NAGPHGKN_00572 568703.LGG_02616 2.58e-226 624.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,3F55H@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran NAGPHGKN_00573 568703.LGG_02617 0.0 958.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HBDR@91061|Bacilli,3F44S@33958|Lactobacillaceae 91061|Bacilli EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) choS - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC NAGPHGKN_00574 568703.LGG_02619 0.0 1414.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,3F486@33958|Lactobacillaceae 91061|Bacilli L DNA helicase - - - - - - - - - - - - AAA_19,UvrD_C_2 NAGPHGKN_00575 568703.LGG_02620 4.46e-189 526.0 COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,4HC4T@91061|Bacilli,3F4VC@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator rlrG - - ko:K21900 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate NAGPHGKN_00576 568703.LGG_02621 2.03e-225 622.0 COG1275@1|root,COG1275@2|Bacteria,1UYTE@1239|Firmicutes,4HGBI@91061|Bacilli,3FBRC@33958|Lactobacillaceae 91061|Bacilli P Voltage-dependent anion channel ydiA - - ko:K11041 ko05150,map05150 - - - ko00000,ko00001,ko02042 2.A.16 - - SLAC1 NAGPHGKN_00577 568703.LGG_02622 5.4e-175 488.0 COG0842@1|root,COG0842@2|Bacteria,1TSWD@1239|Firmicutes,4HB6Z@91061|Bacilli,3F66C@33958|Lactobacillaceae 91061|Bacilli V ABC-2 type transporter yadH - - ko:K01992,ko:K09694 ko02010,map02010 M00252,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 - - ABC2_membrane NAGPHGKN_00578 568703.LGG_02623 1e-169 475.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4IPMF@91061|Bacilli,3FBDQ@33958|Lactobacillaceae 91061|Bacilli V ABC transporter cylA - - ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 M00252,M00254,M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102,3.A.1.130 - - ABC_tran,DUF4162 NAGPHGKN_00579 568703.LGG_02624 9.8e-167 466.0 COG0640@1|root,COG0640@2|Bacteria,1V007@1239|Firmicutes,4HDXJ@91061|Bacilli,3F7E5@33958|Lactobacillaceae 91061|Bacilli K Transcriptional ydfF GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010288,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032791,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097063,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_20 NAGPHGKN_00580 568703.LGG_02625 6.32e-141 399.0 COG1266@1|root,COG1266@2|Bacteria,1VFRX@1239|Firmicutes,4HRQQ@91061|Bacilli,3F4Q0@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi NAGPHGKN_00582 568703.LGG_02626 0.0 957.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F4EQ@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran NAGPHGKN_00583 568703.LGG_02627 1.13e-138 393.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,3F3PN@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yagB - - ko:K06950 - - - - ko00000 - - - HD NAGPHGKN_00584 568703.LGG_02628 4.69e-94 274.0 29Q5J@1|root,30B4H@2|Bacteria,1U7IQ@1239|Firmicutes,4IHFG@91061|Bacilli,3F9S0@33958|Lactobacillaceae 91061|Bacilli K MarR family - - - - - - - - - - - - MarR_2 NAGPHGKN_00585 568703.LGG_02629 0.0 1655.0 COG0178@1|root,COG0178@2|Bacteria,1TP0A@1239|Firmicutes,4HTKA@91061|Bacilli,3FC8R@33958|Lactobacillaceae 91061|Bacilli L excinuclease ABC uvrA3 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran NAGPHGKN_00586 568703.LGG_02630 9.22e-246 674.0 COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,4HAZ2@91061|Bacilli,3F414@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase family protein yghZ - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red NAGPHGKN_00587 568703.LGG_02631 5.39e-183 510.0 COG0561@1|root,COG0561@2|Bacteria,1V8IN@1239|Firmicutes,4HJUX@91061|Bacilli,3F5CU@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - - - - - - - - - - - Hydrolase_3 NAGPHGKN_00588 568703.LGG_02632 3.33e-78 232.0 29PSZ@1|root,30AR5@2|Bacteria,1U708@1239|Firmicutes,4IGUJ@91061|Bacilli,3F8T2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00589 314315.LCA_0323 1.71e-17 76.6 2DKPT@1|root,30A91@2|Bacteria,1U6CF@1239|Firmicutes,4IG44@91061|Bacilli,3F7KP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF2187 NAGPHGKN_00590 568703.LGG_02634 2.65e-149 421.0 COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,4HM4F@91061|Bacilli,3F5F5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 NAGPHGKN_00591 568703.LGG_02635 3.55e-163 456.0 COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HJ9X@91061|Bacilli,3FC5R@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpmB - - ko:K15640 - - - - ko00000 - - - His_Phos_1 NAGPHGKN_00592 568703.LGG_02636 4.01e-194 538.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,3F47B@33958|Lactobacillaceae 91061|Bacilli S hydrolase yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 NAGPHGKN_00593 568703.LGG_02637 1.38e-117 335.0 COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,4HHJ9@91061|Bacilli,3F3RG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - Cauli_VI,RNase_H NAGPHGKN_00594 568703.LGG_02638 9.25e-213 589.0 COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,4HCXX@91061|Bacilli,3F4HW@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate NAGPHGKN_00595 568703.LGG_02639 4.76e-288 786.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4H9M3@91061|Bacilli,3F4AH@33958|Lactobacillaceae 91061|Bacilli EK Aminotransferase, class I - - - - - - - - - - - - Aminotran_1_2 NAGPHGKN_00596 568703.LGG_02641 3.7e-60 186.0 2BNCG@1|root,32H06@2|Bacteria,1U7X9@1239|Firmicutes,4IHUN@91061|Bacilli,3FAAB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00597 568703.LGG_02642 5.18e-75 224.0 2E9Y3@1|root,3343R@2|Bacteria,1VFF0@1239|Firmicutes,4HPUY@91061|Bacilli,3F8BC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00598 568703.LGG_02643 3.1e-254 701.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA NAGPHGKN_00599 568703.LGG_02644 5.11e-149 421.0 COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,4HB4E@91061|Bacilli,3FB62@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF554) ydfK - - ko:K07150 - - - - ko00000 - - - DUF554 NAGPHGKN_00600 568703.LGG_02645 4.31e-115 329.0 29P3K@1|root,30AWC@2|Bacteria,1U76S@1239|Firmicutes,4IH1K@91061|Bacilli,3F91T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00602 568703.LGG_02647 0.0 1244.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F5D3@33958|Lactobacillaceae 91061|Bacilli GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 fruC - 2.7.1.202 ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB NAGPHGKN_00603 568703.LGG_02648 1.94e-216 598.0 COG1105@1|root,COG1105@2|Bacteria,1TTI9@1239|Firmicutes,4HCRN@91061|Bacilli,3F537@33958|Lactobacillaceae 91061|Bacilli H pfkB family carbohydrate kinase fruK-1 - 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB NAGPHGKN_00604 568703.LGG_02649 2.02e-168 471.0 COG1737@1|root,COG1737@2|Bacteria,1TP26@1239|Firmicutes,4HDKG@91061|Bacilli,3F681@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family rpl - - - - - - - - - - - HTH_6,SIS NAGPHGKN_00605 568703.LGG_02650 0.0 1025.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,3F3WI@33958|Lactobacillaceae 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N NAGPHGKN_00606 568703.LGG_02656 0.0 991.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,4HM1D@91061|Bacilli,3F50J@33958|Lactobacillaceae 91061|Bacilli H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase yclC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61,4.1.1.98 ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 M00117 R01238,R04985,R04986,R10213 RC00391,RC03086 ko00000,ko00001,ko00002,ko01000 - - - UbiD NAGPHGKN_00607 568703.LGG_02657 1.32e-132 376.0 COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4HFZX@91061|Bacilli,3F5PD@33958|Lactobacillaceae 91061|Bacilli H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein NAGPHGKN_00608 568703.LGG_02658 2.69e-310 848.0 COG0471@1|root,COG0471@2|Bacteria,1V093@1239|Firmicutes,4HQP0@91061|Bacilli,3F3VN@33958|Lactobacillaceae 91061|Bacilli P Sodium:sulfate symporter transmembrane region - - - - - - - - - - - - Na_sulph_symp NAGPHGKN_00609 568703.LGG_02659 1.15e-203 565.0 COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4HWQQ@91061|Bacilli,3F4CY@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate NAGPHGKN_00610 568703.LGG_02660 1.49e-97 283.0 2F603@1|root,33YIJ@2|Bacteria,1VX0V@1239|Firmicutes,4HXF9@91061|Bacilli,3F6YU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00611 568703.LGG_02661 1.95e-94 276.0 COG1846@1|root,COG1846@2|Bacteria,1VMZX@1239|Firmicutes,4HMTC@91061|Bacilli,3F82U@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_27,MarR,MarR_2 NAGPHGKN_00612 568703.LGG_02662 3.16e-312 853.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3FCCM@33958|Lactobacillaceae 91061|Bacilli U Major Facilitator Superfamily - - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 NAGPHGKN_00613 543734.LCABL_28390 4.99e-165 462.0 COG0235@1|root,COG0235@2|Bacteria,1V57Z@1239|Firmicutes,4HGYY@91061|Bacilli,3FCAV@33958|Lactobacillaceae 91061|Bacilli G Class II Aldolase and Adducin N-terminal domain - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II NAGPHGKN_00615 543734.LCABL_28410 0.0 880.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HAIT@91061|Bacilli,3FCCE@33958|Lactobacillaceae 91061|Bacilli G PTS system sugar-specific permease component pts36C - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT NAGPHGKN_00616 1423732.BALS01000032_gene209 6.21e-68 206.0 COG3414@1|root,COG3414@2|Bacteria,1VAU7@1239|Firmicutes,4IR9X@91061|Bacilli,3F7JF@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_IIB NAGPHGKN_00617 543734.LCABL_28430 1.7e-88 262.0 COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes,4HPPC@91061|Bacilli,3F7U5@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 pts36A - 2.7.1.200 ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_EIIA_2 NAGPHGKN_00618 1423732.BALS01000067_gene2173 5.58e-156 441.0 COG1349@1|root,COG1349@2|Bacteria,1V1VH@1239|Firmicutes,4HG12@91061|Bacilli,3FC5U@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain rdrB - - ko:K02444,ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR NAGPHGKN_00620 1423732.BALS01000067_gene2174 6.22e-211 583.0 COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,4H9QT@91061|Bacilli,3F4WZ@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde rhaD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.2.19 ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01785,R02263 RC00438,RC00599,RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II NAGPHGKN_00621 568703.LGG_02688 0.0 890.0 COG4806@1|root,COG4806@2|Bacteria,1TS42@1239|Firmicutes,4HBQP@91061|Bacilli,3F5GK@33958|Lactobacillaceae 91061|Bacilli G L-rhamnose isomerase (RhaA) rhaA GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 2.7.1.5,5.3.1.14 ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01902,R02437,R03014 RC00002,RC00017,RC00434 ko00000,ko00001,ko01000 - - - RhaA NAGPHGKN_00622 568703.LGG_02689 4.22e-74 221.0 COG3254@1|root,COG3254@2|Bacteria,1VA1C@1239|Firmicutes,4HM5P@91061|Bacilli,3F70M@33958|Lactobacillaceae 91061|Bacilli G Involved in the anomeric conversion of L-rhamnose rhaM - 5.1.3.32 ko:K03534 - - R10819 RC00563 ko00000,ko01000 - - - rhaM NAGPHGKN_00623 568703.LGG_02690 0.0 985.0 COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,4HB5X@91061|Bacilli,3F3UM@33958|Lactobacillaceae 91061|Bacilli F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate rhaB GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 2.7.1.5 ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01902,R03014 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N NAGPHGKN_00624 568703.LGG_02691 0.0 870.0 COG0477@1|root,COG2814@2|Bacteria,1TRBM@1239|Firmicutes,4HE7W@91061|Bacilli,3F5E4@33958|Lactobacillaceae 91061|Bacilli P Sugar (and other) transporter iolF GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K06610 - - - - ko00000,ko02000 2.A.1.1.27 - - MFS_1,Sugar_tr NAGPHGKN_00625 568703.LGG_02692 4.24e-247 678.0 COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TS6T@1239|Firmicutes,4IQ7R@91061|Bacilli,3FBGG@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,HTH_18 NAGPHGKN_00626 568703.LGG_02693 5.2e-276 754.0 COG1062@1|root,COG1062@2|Bacteria,1TP8E@1239|Firmicutes,4HAH9@91061|Bacilli,3F3QP@33958|Lactobacillaceae 91061|Bacilli C Zn-dependent alcohol dehydrogenases, class III adhC - 1.1.1.90 ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N NAGPHGKN_00627 568703.LGG_02694 4.69e-86 253.0 28ZBI@1|root,2ZM3D@2|Bacteria,1W5K5@1239|Firmicutes,4I1Q6@91061|Bacilli,3F825@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 NAGPHGKN_00628 568703.LGG_02695 5.54e-156 439.0 2EM6V@1|root,2ZWQA@2|Bacteria,1W53D@1239|Firmicutes,4I25H@91061|Bacilli,3FB3R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00629 568703.LGG_02696 0.0 1142.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein - - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,Malt_amylase_C NAGPHGKN_00630 1423816.BACQ01000033_gene1421 0.0 1051.0 COG5434@1|root,COG5434@2|Bacteria,1TRWY@1239|Firmicutes,4ITNJ@91061|Bacilli,3FA55@33958|Lactobacillaceae 91061|Bacilli M Right handed beta helix region - - - - - - - - - - - - Gram_pos_anchor NAGPHGKN_00631 1423816.BACQ01000033_gene1420 6.74e-100 305.0 2E4QH@1|root,32ZJ3@2|Bacteria,1V374@1239|Firmicutes,4I0YF@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00632 543734.LCABL_28520 0.0 938.0 COG5434@1|root,COG5434@2|Bacteria,1UHQG@1239|Firmicutes,4ISXY@91061|Bacilli 91061|Bacilli M Heparinase II/III N-terminus - - - - - - - - - - - - Hepar_II_III,Hepar_II_III_N NAGPHGKN_00633 35754.JNYJ01000001_gene7410 0.000638 44.3 COG1862@1|root,COG1862@2|Bacteria,2IQSP@201174|Actinobacteria,4DFMC@85008|Micromonosporales 201174|Actinobacteria U Preprotein translocase subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC NAGPHGKN_00634 1423816.BACQ01000033_gene1417 2.95e-85 253.0 COG2893@1|root,COG2893@2|Bacteria,1W0I6@1239|Firmicutes 1239|Firmicutes G PTS system fructose IIA component - - - ko:K02744 ko00052,ko02060,map00052,map02060 M00277,M00287 R08366,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.4,4.A.6.1.5 - - EIIA-man NAGPHGKN_00635 1423816.BACQ01000033_gene1416 7.09e-184 512.0 COG3716@1|root,COG3716@2|Bacteria,1TSQF@1239|Firmicutes,4HEP4@91061|Bacilli,3F66Y@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component agaD - - ko:K02747 ko00052,ko02060,map00052,map02060 M00277 R08366 RC00017 ko00000,ko00001,ko00002,ko02000 4.A.6.1.4 - - EIID-AGA NAGPHGKN_00636 1423816.BACQ01000033_gene1415 4.89e-172 482.0 COG3715@1|root,COG3715@2|Bacteria,1TRMS@1239|Firmicutes,4HDP2@91061|Bacilli,3FC9G@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02746 ko00052,ko02060,map00052,map02060 M00277 R08366 RC00017 ko00000,ko00001,ko00002,ko02000 4.A.6.1.4 - - EII-Sor NAGPHGKN_00637 1423816.BACQ01000033_gene1414 1.75e-66 204.0 COG3444@1|root,COG3444@2|Bacteria,1V20H@1239|Firmicutes,4HGNG@91061|Bacilli,3FC7T@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - - ko:K02745 ko00052,ko02060,map00052,map02060 M00277 R08366 RC00017 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.4 - - PTSIIB_sorb NAGPHGKN_00638 1423732.BALS01000067_gene2179 7.49e-26 97.4 COG3444@1|root,COG3444@2|Bacteria 2|Bacteria G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity agaV - 2.7.1.191 ko:K02745,ko:K02794 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277 R02630,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.6.1.4 - - PTSIIB_sorb NAGPHGKN_00639 1423732.BALS01000067_gene2180 7.7e-258 709.0 COG4225@1|root,COG4225@2|Bacteria,1TR4A@1239|Firmicutes,4HCM9@91061|Bacilli,3F5YB@33958|Lactobacillaceae 91061|Bacilli S Glycosyl Hydrolase Family 88 ugl GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0015929,GO:0016052,GO:0016787,GO:0016798,GO:0033931,GO:0043170,GO:0044238,GO:0044419,GO:0051704,GO:0052757,GO:0071704,GO:1901575 3.2.1.180 ko:K18581 - - R10867 RC00049,RC02427 ko00000,ko01000 - GH88 - Glyco_hydro_88 NAGPHGKN_00640 543734.LCABL_28590 1.8e-131 380.0 2DBRG@1|root,2ZAKM@2|Bacteria,1UQ8F@1239|Firmicutes,4HHHY@91061|Bacilli,3F6PP@33958|Lactobacillaceae 91061|Bacilli S Psort location Cytoplasmic, score - - - - - - - - - - - - - NAGPHGKN_00641 543734.LCABL_28600 5.57e-141 402.0 COG1414@1|root,COG1414@2|Bacteria,1V8YE@1239|Firmicutes,4HIR8@91061|Bacilli,3F4Y3@33958|Lactobacillaceae 91061|Bacilli K Bacterial transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR NAGPHGKN_00642 1423732.BALS01000067_gene2184 2.55e-181 506.0 COG3717@1|root,COG3717@2|Bacteria,1TP4X@1239|Firmicutes,4HBJH@91061|Bacilli,3F4U4@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate kduI - 5.3.1.17 ko:K01815 ko00040,map00040 - R04383 RC00541 ko00000,ko00001,ko01000 - - - KduI NAGPHGKN_00643 543734.LCABL_28620 2.15e-175 491.0 COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,4HAMW@91061|Bacilli,3F4N6@33958|Lactobacillaceae 91061|Bacilli IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) kduD - 1.1.1.127 ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 NAGPHGKN_00644 543734.LCABL_28630 6.85e-114 331.0 COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,3F6AY@33958|Lactobacillaceae 91061|Bacilli G KDPG and KHG aldolase eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase NAGPHGKN_00645 543734.LCABL_28640 2.79e-192 539.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,4HT5E@91061|Bacilli,3FC26@33958|Lactobacillaceae 91061|Bacilli G pfkB family carbohydrate kinase kdgK - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB NAGPHGKN_00646 568703.LGG_02699 2.58e-156 439.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,3F43N@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A NAGPHGKN_00647 1423816.BACQ01000033_gene1403 0.0 1307.0 COG1196@1|root,COG5492@1|root,COG1196@2|Bacteria,COG5492@2|Bacteria,1TQ2K@1239|Firmicutes,4HBG8@91061|Bacilli,3F9RZ@33958|Lactobacillaceae 91061|Bacilli N Polysaccharide lyase family 8, N terminal alpha-helical domain hylB GO:0005575,GO:0005576 4.2.2.1 ko:K01727 - - - - ko00000,ko01000 - PL8 - Big_2,F5_F8_type_C,FIVAR,Gram_pos_anchor,Lyase_8,Lyase_8_C,Lyase_8_N,SLH,YSIRK_signal NAGPHGKN_00648 1231336.L248_3009 1.76e-246 707.0 COG3345@1|root,COG3345@2|Bacteria,1TSZB@1239|Firmicutes,4HDHK@91061|Bacilli,3F5UE@33958|Lactobacillaceae 91061|Bacilli G Melibiase - - - - - - - - - - - - Glyco_hydro_36N,Melibiase NAGPHGKN_00649 457396.CSBG_03067 9.75e-54 174.0 COG3444@1|root,COG3444@2|Bacteria,1V46G@1239|Firmicutes,24I8X@186801|Clostridia,36J3A@31979|Clostridiaceae 186801|Clostridia G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb NAGPHGKN_00650 457396.CSBG_03066 5.55e-83 257.0 COG3716@1|root,COG3716@2|Bacteria,1UZYR@1239|Firmicutes,25C3F@186801|Clostridia,36WNW@31979|Clostridiaceae 186801|Clostridia G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA NAGPHGKN_00651 1158607.UAU_02705 2.21e-79 247.0 COG3715@1|root,COG3715@2|Bacteria,1UYP8@1239|Firmicutes,4HU18@91061|Bacilli,4B1R8@81852|Enterococcaceae 1239|Firmicutes G PTS system sorbose-specific iic component XK27_08455 - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor NAGPHGKN_00652 1158607.UAU_02706 9.21e-30 111.0 COG2893@1|root,COG2893@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man NAGPHGKN_00653 1122152.AUEI01000013_gene377 8.35e-08 55.8 COG2188@1|root,COG2188@2|Bacteria,1VUZN@1239|Firmicutes,4I39K@91061|Bacilli,3F71Y@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - GntR,UTRA NAGPHGKN_00654 1045854.WKK_01725 3.77e-34 131.0 COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,4HARD@91061|Bacilli,4AX23@81850|Leuconostocaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor araR - - ko:K02103 - - - - ko00000,ko03000 - - - GntR,Peripla_BP_3 NAGPHGKN_00655 568703.LGG_02701 0.0 932.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9TM@91061|Bacilli,3F4W5@33958|Lactobacillaceae 91061|Bacilli G Family 4 glycosyl hydrolase C-terminal domain - - 3.2.1.122 ko:K01232 ko00500,map00500 - R00837,R00838,R06113 RC00049 ko00000,ko00001,ko01000 - GH4 - Glyco_hydro_4,Glyco_hydro_4C NAGPHGKN_00656 568703.LGG_02702 0.0 1018.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,3F44V@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system, EIIB - - 2.7.1.199,2.7.1.208 ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266 R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.3 - - PTS_EIIB,PTS_EIIC NAGPHGKN_00657 543734.LCABL_00570 1.26e-133 395.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F46B@33958|Lactobacillaceae 91061|Bacilli V ABC-type multidrug transport system, ATPase and permease components - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NAGPHGKN_00658 543734.LCABL_00570 2.24e-93 290.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F46B@33958|Lactobacillaceae 91061|Bacilli V ABC-type multidrug transport system, ATPase and permease components - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NAGPHGKN_00659 543734.LCABL_00560 6.58e-136 392.0 COG1396@1|root,COG1396@2|Bacteria,1UZI0@1239|Firmicutes,4I40C@91061|Bacilli,3F837@33958|Lactobacillaceae 91061|Bacilli K Transcriptional activator, Rgg GadR MutR family - - - - - - - - - - - - HTH_3 NAGPHGKN_00660 568703.LGG_02704 3.33e-161 453.0 COG1737@1|root,COG1737@2|Bacteria,1TR75@1239|Firmicutes,4HJU7@91061|Bacilli,3F6Y6@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS NAGPHGKN_00661 568703.LGG_02705 2.22e-78 235.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,3FC0X@33958|Lactobacillaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ptbA - 2.7.1.208 ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1 NAGPHGKN_00662 568703.LGG_02705 9.61e-15 69.7 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,3FC0X@33958|Lactobacillaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ptbA - 2.7.1.208 ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1 NAGPHGKN_00664 568703.LGG_02707 1.96e-177 494.0 2DBAP@1|root,2Z844@2|Bacteria,1TQX7@1239|Firmicutes,4HABQ@91061|Bacilli,3F5QS@33958|Lactobacillaceae 91061|Bacilli S KDGP aldolase - - 4.1.2.14 ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 M00061,M00631 R05605 RC00307,RC00435 ko00000,ko00001,ko00002,ko01000 - - - KDGP_aldolase NAGPHGKN_00665 568703.LGG_02708 3.41e-257 706.0 COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,4HC3U@91061|Bacilli,3F4MN@33958|Lactobacillaceae 91061|Bacilli H L-seryl-tRNA selenium transferase selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - SelA NAGPHGKN_00666 568703.LGG_02709 3.01e-275 752.0 COG3964@1|root,COG3964@2|Bacteria,1TPXM@1239|Firmicutes,4HBNV@91061|Bacilli,3F4S7@33958|Lactobacillaceae 91061|Bacilli S Amidohydrolase family dho - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 NAGPHGKN_00667 568703.LGG_02710 1.94e-152 429.0 2CHGF@1|root,2Z7QV@2|Bacteria,1TRJJ@1239|Firmicutes,4HC0E@91061|Bacilli,3F5QZ@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4310) - - - - - - - - - - - - DUF4310 NAGPHGKN_00668 568703.LGG_02711 2.89e-177 494.0 28HBR@1|root,2Z7NQ@2|Bacteria,1TQ2N@1239|Firmicutes,4HAZ6@91061|Bacilli,3F5N2@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4311) - - - - - - - - - - - - DUF4311 NAGPHGKN_00669 568703.LGG_02712 6.76e-75 224.0 2AJY2@1|root,31AM7@2|Bacteria,1VQQN@1239|Firmicutes,4IRVB@91061|Bacilli,3F93K@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4312) - - - - - - - - - - - - DUF4312 NAGPHGKN_00670 1423816.BACQ01000033_gene1388 1.23e-80 239.0 292C3@1|root,2ZPWH@2|Bacteria,1V7VZ@1239|Firmicutes,4HIX7@91061|Bacilli,3F6XI@33958|Lactobacillaceae 91061|Bacilli S Glycine-rich SFCGS - - - - - - - - - - - - Gly_rich_SFCGS NAGPHGKN_00671 568703.LGG_02714 1.33e-70 213.0 2CG0N@1|root,32S2X@2|Bacteria,1VI2Z@1239|Firmicutes,4HQX6@91061|Bacilli,3F8H0@33958|Lactobacillaceae 91061|Bacilli S PRD domain - - - - - - - - - - - - PRD NAGPHGKN_00672 568703.LGG_02715 0.0 1199.0 COG3711@1|root,COG3711@2|Bacteria,1U0UU@1239|Firmicutes,4HJZ1@91061|Bacilli,3F5NV@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - HTH_11,PRD NAGPHGKN_00673 568703.LGG_02716 2.41e-158 444.0 COG0176@1|root,COG0176@2|Bacteria,1V4IX@1239|Firmicutes,4HJYI@91061|Bacilli,3FCEA@33958|Lactobacillaceae 91061|Bacilli H Pfam:Transaldolase - - - - - - - - - - - - TAL_FSA NAGPHGKN_00674 568703.LGG_02717 1.74e-82 244.0 COG3731@1|root,COG3731@2|Bacteria,1VG8V@1239|Firmicutes,4HPTF@91061|Bacilli,3F7KY@33958|Lactobacillaceae 91061|Bacilli G PTS system glucitol/sorbitol-specific IIA component - - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA NAGPHGKN_00675 568703.LGG_02718 1.88e-252 694.0 COG3732@1|root,COG3732@2|Bacteria,1TQ8F@1239|Firmicutes,4HA7E@91061|Bacilli,3F5AP@33958|Lactobacillaceae 91061|Bacilli G Sorbitol phosphotransferase enzyme II N-terminus srlE - 2.7.1.198 ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - EIIBC-GUT_C,EIIBC-GUT_N NAGPHGKN_00676 568703.LGG_02719 1.43e-131 373.0 COG3730@1|root,COG3730@2|Bacteria,1URER@1239|Firmicutes,4HEHX@91061|Bacilli,3F445@33958|Lactobacillaceae 91061|Bacilli G PTS system enzyme II sorbitol-specific factor srlA - - ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.4.1 - - EII-GUT NAGPHGKN_00677 568703.LGG_02720 3.59e-113 325.0 COG4578@1|root,COG4578@2|Bacteria,1VHYU@1239|Firmicutes,4HP9S@91061|Bacilli,3F7F5@33958|Lactobacillaceae 91061|Bacilli K Glucitol operon activator protein (GutM) srlM1 - - - - - - - - - - - GutM NAGPHGKN_00678 568703.LGG_02721 0.0 1185.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1UZ36@1239|Firmicutes,4HDUK@91061|Bacilli,3F5E0@33958|Lactobacillaceae 91061|Bacilli GKT Mga helix-turn-helix domain srlM - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2 NAGPHGKN_00679 568703.LGG_02722 4.82e-184 512.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli,3F4CR@33958|Lactobacillaceae 91061|Bacilli IQ NAD dependent epimerase/dehydratase family srlD - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short NAGPHGKN_00680 543734.LCABL_03270 5.59e-33 116.0 COG2161@1|root,COG2161@2|Bacteria,1VAJF@1239|Firmicutes,4HPRS@91061|Bacilli,3F7SP@33958|Lactobacillaceae 91061|Bacilli D Antitoxin component of a toxin-antitoxin (TA) module - - - ko:K19159 - - - - ko00000,ko02048 - - - PhdYeFM_antitox NAGPHGKN_00681 1334046.AYTB01000002_gene1915 6.82e-40 133.0 COG4115@1|root,COG4115@2|Bacteria,1VEN0@1239|Firmicutes,4HRVW@91061|Bacilli,26HNW@186818|Planococcaceae 91061|Bacilli S YoeB-like toxin of bacterial type II toxin-antitoxin system yoeB - - ko:K19158 - - - - ko00000,ko01000,ko02048 - - - YoeB_toxin NAGPHGKN_00682 568703.LGG_02723 1.83e-176 491.0 COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,4H9W0@91061|Bacilli,3F43P@33958|Lactobacillaceae 91061|Bacilli G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source araD GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II NAGPHGKN_00683 568703.LGG_02724 3.56e-194 538.0 COG0561@1|root,COG0561@2|Bacteria,1TR2E@1239|Firmicutes,4HCEA@91061|Bacilli,3F4G9@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 NAGPHGKN_00684 568703.LGG_02725 2.13e-212 587.0 COG3623@1|root,COG3623@2|Bacteria,1TSMS@1239|Firmicutes,4HBBU@91061|Bacilli,3F5GZ@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase-like TIM barrel sga - 5.1.3.22 ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R03244 RC00540 ko00000,ko00001,ko00002,ko01000 - - - AP_endonuc_2 NAGPHGKN_00685 568703.LGG_02727 4.27e-176 491.0 COG1349@1|root,COG1349@2|Bacteria,1UYQX@1239|Firmicutes,4HMB5@91061|Bacilli,3F6Z8@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR NAGPHGKN_00686 568703.LGG_02728 1.51e-147 416.0 COG0269@1|root,COG0269@2|Bacteria,1TSHP@1239|Firmicutes,4HCA8@91061|Bacilli,3F3YT@33958|Lactobacillaceae 91061|Bacilli G Orotidine 5'-phosphate decarboxylase / HUMPS family ulaD - 4.1.1.85,4.1.2.43 ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 M00345,M00550,M00580 R05338,R07125 RC00421,RC00422,RC01721 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase NAGPHGKN_00687 568703.LGG_02730 3.93e-60 185.0 COG3414@1|root,COG3414@2|Bacteria,1VHNP@1239|Firmicutes,4IR7Z@91061|Bacilli,3F78S@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit sgaB - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB NAGPHGKN_00688 568703.LGG_02731 0.0 976.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HB7T@91061|Bacilli,3FC40@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component sgaT - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT NAGPHGKN_00689 568703.LGG_02732 1.64e-103 299.0 COG1762@1|root,COG1762@2|Bacteria,1V892@1239|Firmicutes,4IQ69@91061|Bacilli,3F6HA@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_EIIA_2 NAGPHGKN_00690 568703.LGG_02733 3.47e-270 738.0 COG2220@1|root,COG2220@2|Bacteria,1TSFV@1239|Firmicutes,4HBNW@91061|Bacilli,3F58F@33958|Lactobacillaceae 91061|Bacilli S Beta-lactamase superfamily domain ulaG - - ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 M00550 R07677 RC02793 ko00000,ko00001,ko00002,ko01000 - - - Lactamase_B_2,Lactamase_B_3 NAGPHGKN_00691 568703.LGG_02734 0.0 2664.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,3F3M5@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase S8 family prtP - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - PA,Peptidase_S8,SLAP,fn3_5 NAGPHGKN_00692 568703.LGG_02735 5.44e-56 174.0 2AII8@1|root,31906@2|Bacteria,1U82Q@1239|Firmicutes,4II04@91061|Bacilli,3FAGG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00693 568703.LGG_02736 2.79e-199 553.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,4HE30@91061|Bacilli,3F3ZI@33958|Lactobacillaceae 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK NAGPHGKN_00694 568703.LGG_02737 3.03e-230 634.0 COG1446@1|root,COG1446@2|Bacteria,1TSWB@1239|Firmicutes,4HED0@91061|Bacilli,3F3SI@33958|Lactobacillaceae 91061|Bacilli E Asparaginase asnA2 - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase_2 NAGPHGKN_00695 568703.LGG_02738 1.68e-310 847.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HBQA@91061|Bacilli,3F5AY@33958|Lactobacillaceae 91061|Bacilli E Peptidase family M20/M25/M40 - - - - - - - - - - - - Peptidase_M20 NAGPHGKN_00696 568703.LGG_02739 2.04e-167 468.0 COG2188@1|root,COG2188@2|Bacteria,1V338@1239|Firmicutes,4HGUM@91061|Bacilli,3F682@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA NAGPHGKN_00697 568703.LGG_02740 4.11e-273 749.0 COG0477@1|root,COG2814@2|Bacteria,1TQZ7@1239|Firmicutes,4HERG@91061|Bacilli,3F54C@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein - - - - - - - - - - - - MFS_1 NAGPHGKN_00698 568703.LGG_02741 5.24e-259 708.0 COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,4HTW2@91061|Bacilli,3F4ZS@33958|Lactobacillaceae 91061|Bacilli G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos NAGPHGKN_00699 568703.LGG_02758 6.25e-117 334.0 COG0454@1|root,COG0456@2|Bacteria,1VA31@1239|Firmicutes,4HH60@91061|Bacilli,3FBXQ@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - ko:K03828 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 NAGPHGKN_00700 568703.LGG_02759 7.2e-144 406.0 COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,4HHQT@91061|Bacilli,3F4BS@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain yjhB - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,Nudix_N NAGPHGKN_00702 568703.LGG_02761 1.53e-126 360.0 COG1476@1|root,COG1476@2|Bacteria,1VDCA@1239|Firmicutes,4HN0T@91061|Bacilli,3F7ZF@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - DUF1700,HTH_3,HTH_31 NAGPHGKN_00703 568703.LGG_02762 0.0 3413.0 COG1196@1|root,COG1501@1|root,COG1196@2|Bacteria,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HEJM@91061|Bacilli,3FC1B@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 31 family - - - - - - - - - - - - DUF4968,DUF5110,F5_F8_type_C,FIVAR,Gal_mutarotas_2,Glyco_hydro_31 NAGPHGKN_00704 568703.LGG_02763 2.06e-170 475.0 COG1051@1|root,COG4111@1|root,COG1051@2|Bacteria,COG4111@2|Bacteria,1UZ4E@1239|Firmicutes,4IPMJ@91061|Bacilli,3FBCZ@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX NAGPHGKN_00705 568703.LGG_02764 2.68e-139 392.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli,3F41F@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family pncA - - - - - - - - - - - Isochorismatase NAGPHGKN_00706 568703.LGG_02765 0.0 913.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP nadC2 - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase NAGPHGKN_00707 568703.LGG_02766 6.15e-170 474.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,3F4E3@33958|Lactobacillaceae 91061|Bacilli C glycerophosphoryl diester phosphodiesterase glpQ1 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD NAGPHGKN_00708 568703.LGG_02767 4.05e-70 213.0 COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,4HH49@91061|Bacilli,3F6GQ@33958|Lactobacillaceae 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc NAGPHGKN_00709 568703.LGG_02768 0.0 897.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HARC@91061|Bacilli,3FC76@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein ugpB - - ko:K05813 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - SBP_bac_8 NAGPHGKN_00710 568703.LGG_02769 6.89e-191 530.0 COG0395@1|root,COG0395@2|Bacteria,1TR0I@1239|Firmicutes,4HB8C@91061|Bacilli,3F4Q5@33958|Lactobacillaceae 91061|Bacilli G ABC transporter permease ugpE - - ko:K05815 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - BPD_transp_1 NAGPHGKN_00711 568703.LGG_02770 2.51e-208 577.0 COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,4HCD0@91061|Bacilli,3F464@33958|Lactobacillaceae 91061|Bacilli P ABC-type sugar transport systems, permease components - - - ko:K05814 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - BPD_transp_1 NAGPHGKN_00712 568703.LGG_02771 9.24e-269 735.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HA50@91061|Bacilli,3FC3B@33958|Lactobacillaceae 91061|Bacilli E Belongs to the ABC transporter superfamily ugpC - 3.6.3.20 ko:K05816,ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.3 - - ABC_tran,TOBE_2 NAGPHGKN_00713 568703.LGG_02772 7.56e-286 783.0 COG0477@1|root,COG2814@2|Bacteria,1TRZB@1239|Firmicutes,4HC28@91061|Bacilli,3F4VZ@33958|Lactobacillaceae 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 NAGPHGKN_00714 568703.LGG_02773 1.69e-186 518.0 COG2367@1|root,COG2367@2|Bacteria,1VAJP@1239|Firmicutes 1239|Firmicutes V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 NAGPHGKN_00715 568703.LGG_02774 5.13e-244 670.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,3F4K3@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase NAGPHGKN_00716 568703.LGG_02775 1.47e-185 519.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,3F4T1@33958|Lactobacillaceae 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 NAGPHGKN_00717 568703.LGG_02776 5.24e-208 577.0 COG1737@1|root,COG1737@2|Bacteria,1V26Y@1239|Firmicutes,4IQVW@91061|Bacilli,3FBJG@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS NAGPHGKN_00718 568703.LGG_02777 5.58e-104 301.0 COG3444@1|root,COG3444@2|Bacteria,1V58C@1239|Firmicutes,4HJ9Y@91061|Bacilli,3F79W@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb NAGPHGKN_00719 568703.LGG_02778 5.03e-192 533.0 COG3716@1|root,COG3716@2|Bacteria,1UZG2@1239|Firmicutes,4IQM5@91061|Bacilli,3F5FR@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA NAGPHGKN_00720 568703.LGG_02779 3.98e-172 483.0 COG3715@1|root,COG3715@2|Bacteria,1UYP8@1239|Firmicutes,4IQM3@91061|Bacilli,3F5ZV@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component XK27_08455 - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor NAGPHGKN_00722 568703.LGG_02781 7.17e-258 706.0 COG3568@1|root,COG3568@2|Bacteria,1U5BI@1239|Firmicutes,4HE49@91061|Bacilli,3F57I@33958|Lactobacillaceae 91061|Bacilli S endonuclease exonuclease phosphatase family protein - - - - - - - - - - - - Exo_endo_phos NAGPHGKN_00723 568703.LGG_02782 7.62e-219 604.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F4FC@33958|Lactobacillaceae 91061|Bacilli S DHHA1 domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 NAGPHGKN_00724 568703.LGG_02783 3.72e-202 560.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4H9XJ@91061|Bacilli,3FB4Q@33958|Lactobacillaceae 91061|Bacilli S reductase - - 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red NAGPHGKN_00725 568703.LGG_02784 1.23e-96 281.0 COG0789@1|root,COG0789@2|Bacteria,1V4YT@1239|Firmicutes,4HI03@91061|Bacilli,3FC65@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 NAGPHGKN_00726 568703.LGG_02785 3.29e-182 506.0 COG0500@1|root,COG2226@2|Bacteria,1TSAZ@1239|Firmicutes,4HIIG@91061|Bacilli,3F4S0@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase - - - - - - - - - - - - Methyltransf_11 NAGPHGKN_00727 568703.LGG_02787 2.34e-65 199.0 COG2076@1|root,COG2076@2|Bacteria,1VEZX@1239|Firmicutes,4HKXB@91061|Bacilli,3F7D6@33958|Lactobacillaceae 91061|Bacilli U Multidrug resistance protein sugE - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res NAGPHGKN_00728 278963.ATWD01000001_gene1409 8.78e-08 52.4 2DCYN@1|root,2ZFUK@2|Bacteria,3Y95K@57723|Acidobacteria 57723|Acidobacteria S SpoVT / AbrB like domain - - - - - - - - - - - - MazE_antitoxin NAGPHGKN_00729 1231336.L248_2053 1.17e-178 521.0 COG1132@1|root,COG1132@2|Bacteria,1V08F@1239|Firmicutes,4HUKE@91061|Bacilli,3FBEY@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran NAGPHGKN_00730 568703.LGG_02789 1.5e-74 223.0 2E9Y3@1|root,32JRV@2|Bacteria,1TVPM@1239|Firmicutes,4I3SR@91061|Bacilli,3FA3I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00731 568703.LGG_02790 2.09e-48 154.0 2AIE5@1|root,318VJ@2|Bacteria,1U80U@1239|Firmicutes,4IHY8@91061|Bacilli,3FAE7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00732 568703.LGG_02791 5.69e-140 396.0 COG1073@1|root,COG1073@2|Bacteria,1UVV8@1239|Firmicutes,4IE24@91061|Bacilli,3FA2P@33958|Lactobacillaceae 91061|Bacilli S alpha beta - - - - - - - - - - - - - NAGPHGKN_00733 568703.LGG_02792 8.86e-103 298.0 COG0454@1|root,COG0456@2|Bacteria,1VEEJ@1239|Firmicutes,4HP6M@91061|Bacilli,3FBDP@33958|Lactobacillaceae 91061|Bacilli K FR47-like protein yfbM - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 NAGPHGKN_00734 1423732.BALS01000036_gene133 6.78e-100 292.0 COG0241@1|root,COG0241@2|Bacteria,1V6DW@1239|Firmicutes,4HJ23@91061|Bacilli 91061|Bacilli E HAD-hyrolase-like - - - - - - - - - - - - Hydrolase_like NAGPHGKN_00735 568703.LGG_02793 2.78e-170 476.0 COG2365@1|root,COG2365@2|Bacteria,1V6Q5@1239|Firmicutes,4HJKY@91061|Bacilli,3F5X1@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family ptp1 - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 NAGPHGKN_00736 568703.LGG_02794 9.36e-111 318.0 COG0454@1|root,COG0456@2|Bacteria,1V8AJ@1239|Firmicutes,4HPGU@91061|Bacilli,3F6YY@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 NAGPHGKN_00737 568703.LGG_02795 1.69e-158 444.0 2DYM8@1|root,34AAZ@2|Bacteria,1VZP6@1239|Firmicutes,4HZAB@91061|Bacilli,3F99W@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00738 568703.LGG_02796 1.33e-86 256.0 COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli,3F7EV@33958|Lactobacillaceae 91061|Bacilli S ASCH - - - - - - - - - - - - ASCH NAGPHGKN_00739 543734.LCABL_29990 1.18e-104 303.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,3F3YX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase NAGPHGKN_00740 568703.LGG_02798 7.69e-254 697.0 COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,4HEW7@91061|Bacilli,3F4CJ@33958|Lactobacillaceae 91061|Bacilli P Citrate transporter ysdE - - - - - - - - - - - CitMHS NAGPHGKN_00741 568703.LGG_02799 2.23e-134 388.0 29Q2V@1|root,30B3P@2|Bacteria,1U7H9@1239|Firmicutes,4IHDU@91061|Bacilli,3F9PB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00742 568703.LGG_02800 5.64e-315 858.0 COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli,3F541@33958|Lactobacillaceae 91061|Bacilli E Peptidase dimerisation domain dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 NAGPHGKN_00743 568703.LGG_02801 0.0 1026.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 NAGPHGKN_00744 568703.LGG_02802 9.87e-200 563.0 29Q2V@1|root,30B1G@2|Bacteria,1U7DH@1239|Firmicutes,4IH9F@91061|Bacilli,3F9FB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00745 1423816.BACQ01000031_gene1332 0.0 1136.0 COG2207@1|root,COG3507@1|root,COG2207@2|Bacteria,COG3507@2|Bacteria,1V4GS@1239|Firmicutes,4HIT5@91061|Bacilli,3F6QM@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein bgaR - - - - - - - - - - - AraC_binding,HTH_18 NAGPHGKN_00746 1423816.BACQ01000031_gene1330 0.0 971.0 COG2211@1|root,COG2211@2|Bacteria,1U037@1239|Firmicutes,4HBZK@91061|Bacilli,3F4MV@33958|Lactobacillaceae 91061|Bacilli G MFS/sugar transport protein - - - ko:K03292,ko:K16210 - - - - ko00000,ko02000 2.A.2,2.A.2.5 - - MFS_2 NAGPHGKN_00747 1423816.BACQ01000031_gene1329 0.0 1265.0 2DB7A@1|root,2Z7KK@2|Bacteria,1TZSZ@1239|Firmicutes,4HFM6@91061|Bacilli,3F5CP@33958|Lactobacillaceae 91061|Bacilli S Glycosyl hydrolase family 115 - - - - - - - - - - - - Glyco_hydro_115 NAGPHGKN_00748 568703.LGG_02803 0.0 1102.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4JI@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - - - - - - - - - - - E1-E2_ATPase,Hydrolase NAGPHGKN_00749 568703.LGG_02804 4.09e-99 288.0 COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HPDH@91061|Bacilli,3F7R8@33958|Lactobacillaceae 91061|Bacilli O Hsp20/alpha crystallin family hsp1 - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 NAGPHGKN_00750 568703.LGG_02805 1.94e-91 267.0 2F916@1|root,341CT@2|Bacteria,1VY7K@1239|Firmicutes,4HX4B@91061|Bacilli,3F70S@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn NAGPHGKN_00751 568703.LGG_02806 1.99e-284 781.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,3F45X@33958|Lactobacillaceae 91061|Bacilli O serine protease htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 NAGPHGKN_00752 568703.LGG_02809 2.72e-196 543.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,3F3S4@33958|Lactobacillaceae 91061|Bacilli S domain protein vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 NAGPHGKN_00753 568703.LGG_02810 3.66e-183 510.0 COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,3F3PV@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycI - - - - - - - - - - - YycI NAGPHGKN_00754 568703.LGG_02811 0.0 900.0 COG4863@1|root,COG4863@2|Bacteria,1V32Y@1239|Firmicutes,4HG2Q@91061|Bacilli,3F4HR@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycH - - - - - - - - - - - YycH NAGPHGKN_00755 568703.LGG_02812 0.0 1214.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,3F45G@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 NAGPHGKN_00756 568703.LGG_02813 5.24e-169 472.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,3F4FB@33958|Lactobacillaceae 91061|Bacilli K response regulator yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C NAGPHGKN_00757 568703.LGG_02815 1.1e-159 447.0 COG0596@1|root,COG0596@2|Bacteria,1V02M@1239|Firmicutes,4HN2K@91061|Bacilli,3FBGC@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase family - - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 NAGPHGKN_00758 568703.LGG_02816 0.0 897.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease arpJ - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - iSB619.SA_RS09465 BPD_transp_1,SBP_bac_3 NAGPHGKN_00759 568703.LGG_02817 3.99e-299 815.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,3F46X@33958|Lactobacillaceae 91061|Bacilli E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04675 Arginosuc_synth NAGPHGKN_00760 568703.LGG_02818 0.0 913.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,3F4PF@33958|Lactobacillaceae 91061|Bacilli E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 NAGPHGKN_00761 568703.LGG_02819 4.59e-271 741.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4H9V2@91061|Bacilli,3F4FK@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) ybhE - - ko:K09963 - - - - ko00000 - - - DUF871 NAGPHGKN_00762 568703.LGG_02820 3.7e-96 280.0 2DQNY@1|root,337UX@2|Bacteria,1VEZ0@1239|Firmicutes,4HPE2@91061|Bacilli,3F69F@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF3284) - - - - - - - - - - - - DUF3284 NAGPHGKN_00763 568703.LGG_02821 0.0 876.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F4VG@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane chbC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC NAGPHGKN_00764 568703.LGG_02822 8.04e-168 469.0 COG2188@1|root,COG2188@2|Bacteria,1TTCD@1239|Firmicutes,4HEXQ@91061|Bacilli,3F4DA@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein - - - - - - - - - - - - GntR,UTRA NAGPHGKN_00765 568703.LGG_02823 2.7e-68 207.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F6GU@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit pts20B - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB NAGPHGKN_00766 568703.LGG_02824 2.91e-72 217.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,3F6Z5@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose Cellobiose specific IIA subunit celC - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA NAGPHGKN_00767 568703.LGG_02825 5.23e-140 394.0 COG1670@1|root,COG1670@2|Bacteria,1V3W1@1239|Firmicutes,4HH6A@91061|Bacilli,3F6G6@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain yokL3 - - - - - - - - - - - Acetyltransf_3 NAGPHGKN_00768 568703.LGG_02828 1.14e-105 308.0 COG1051@1|root,COG1051@2|Bacteria,1V5NQ@1239|Firmicutes,4HH6Z@91061|Bacilli,3F674@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX NAGPHGKN_00769 568703.LGG_02829 5.71e-116 332.0 COG4639@1|root,COG4639@2|Bacteria,1V2CI@1239|Firmicutes,4HGAU@91061|Bacilli,3FBXH@33958|Lactobacillaceae 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_33 NAGPHGKN_00770 568703.LGG_02830 2.24e-146 412.0 COG1335@1|root,COG1335@2|Bacteria,1V7WN@1239|Firmicutes,4HIYX@91061|Bacilli,3F4WV@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family ycaC - - - - - - - - - - - Isochorismatase NAGPHGKN_00771 568703.LGG_02831 3.98e-98 298.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F5DA@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 NAGPHGKN_00772 568703.LGG_02831 8.74e-201 565.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F5DA@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 NAGPHGKN_00773 568703.LGG_02832 2.44e-269 739.0 COG2807@1|root,COG2807@2|Bacteria,1TP9R@1239|Firmicutes,4H9YZ@91061|Bacilli,3F52B@33958|Lactobacillaceae 91061|Bacilli P Transporter, major facilitator family protein yycB - - ko:K03449 - - - - ko00000,ko02000 2.A.1.17 - - MFS_1 NAGPHGKN_00774 568703.LGG_02833 7.35e-221 609.0 COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,3F40K@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase iolS - - ko:K06607 - - - - ko00000,ko01000 - - - Aldo_ket_red NAGPHGKN_00775 568703.LGG_02834 1.54e-84 249.0 COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes,4HIMF@91061|Bacilli,3F719@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF956) manO - - - - - - - - - - - DUF956 NAGPHGKN_00776 568703.LGG_02836 7.33e-218 601.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component manN - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA NAGPHGKN_00777 568703.LGG_02837 6.18e-173 484.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli,3F3V5@33958|Lactobacillaceae 91061|Bacilli G PTS system manM - - ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277 R02630,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.4 - - EII-Sor NAGPHGKN_00778 568703.LGG_02838 7.73e-231 635.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli,3F4PU@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component manL - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - EIIA-man,PTSIIB_sorb NAGPHGKN_00779 568703.LGG_02839 2.8e-278 764.0 COG0477@1|root,2ZBIK@2|Bacteria,1UG5D@1239|Firmicutes,4H9W5@91061|Bacilli,3FBS8@33958|Lactobacillaceae 91061|Bacilli EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 NAGPHGKN_00780 568703.LGG_02840 6.98e-241 662.0 COG1396@1|root,COG1396@2|Bacteria,1V9XM@1239|Firmicutes,4HJUU@91061|Bacilli,3F79A@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K20373 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 NAGPHGKN_00781 568703.LGG_02841 3.25e-190 529.0 COG1396@1|root,COG1396@2|Bacteria,1W2GY@1239|Firmicutes,4IGZ7@91061|Bacilli,3F8YW@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 NAGPHGKN_00782 568703.LGG_02842 5.07e-203 562.0 COG1396@1|root,COG1396@2|Bacteria,1W2SR@1239|Firmicutes,4I0B2@91061|Bacilli 91061|Bacilli K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 NAGPHGKN_00787 568703.LGG_02846 0.0 1083.0 COG3409@1|root,COG3409@2|Bacteria,1TPV1@1239|Firmicutes,4HCRA@91061|Bacilli,3F5J4@33958|Lactobacillaceae 91061|Bacilli M peptidoglycan-binding domain-containing protein ybfG - - - - - - - - - - - DUF1906,PG_binding_1 NAGPHGKN_00789 568703.LGG_02848 8.57e-157 452.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease XK27_05795 - - ko:K17073,ko:K17074 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.20 - - BPD_transp_1,SBP_bac_3 NAGPHGKN_00790 568703.LGG_02848 3.76e-177 506.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease XK27_05795 - - ko:K17073,ko:K17074 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.20 - - BPD_transp_1,SBP_bac_3 NAGPHGKN_00791 568703.LGG_02849 1.89e-172 481.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - - ko:K17076 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.20 - - ABC_tran NAGPHGKN_00792 568703.LGG_02850 7.62e-53 166.0 2AHQJ@1|root,3182T@2|Bacteria,1U7RB@1239|Firmicutes,4IHNN@91061|Bacilli,3FA24@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00793 568703.LGG_02851 3.33e-303 827.0 COG1653@1|root,COG1653@2|Bacteria,1TR68@1239|Firmicutes,4HX7S@91061|Bacilli,3F98R@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 NAGPHGKN_00794 568703.LGG_00891 3.97e-23 93.2 2BT3F@1|root,32N80@2|Bacteria,1U8CV@1239|Firmicutes,4IIAU@91061|Bacilli,3FAUG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00795 568703.LGG_02853 1.89e-167 468.0 COG5523@1|root,COG5523@2|Bacteria,1VCPB@1239|Firmicutes,4HN1D@91061|Bacilli,3F69G@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF975) - - - - - - - - - - - - DUF975 NAGPHGKN_00796 568703.LGG_02854 7.92e-76 226.0 COG4918@1|root,COG4918@2|Bacteria,1U783@1239|Firmicutes,4IH2X@91061|Bacilli,3F93I@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn NAGPHGKN_00797 568703.LGG_02855 9.87e-70 210.0 298U1@1|root,2ZVY8@2|Bacteria,1W3JF@1239|Firmicutes,4I1SS@91061|Bacilli,3F7JE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00798 568703.LGG_02857 9.49e-59 184.0 COG3402@1|root,COG3402@2|Bacteria,1VFTS@1239|Firmicutes,4HGMB@91061|Bacilli,3F6GM@33958|Lactobacillaceae 91061|Bacilli S Bacterial PH domain ydbS - - ko:K09167 - - - - ko00000 - - - bPH_2 NAGPHGKN_00799 568703.LGG_02857 8.05e-27 101.0 COG3402@1|root,COG3402@2|Bacteria,1VFTS@1239|Firmicutes,4HGMB@91061|Bacilli,3F6GM@33958|Lactobacillaceae 91061|Bacilli S Bacterial PH domain ydbS - - ko:K09167 - - - - ko00000 - - - bPH_2 NAGPHGKN_00800 568703.LGG_02858 0.0 991.0 COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,3F3VB@33958|Lactobacillaceae 91061|Bacilli S Bacterial PH domain ydbT - - ko:K08981 - - - - ko00000 - - - bPH_2 NAGPHGKN_00801 568703.LGG_02859 8.69e-183 508.0 COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,4HBQT@91061|Bacilli,3F8H5@33958|Lactobacillaceae 91061|Bacilli S AAA ATPase domain - - - - - - - - - - - - AAA_15,AAA_21,AAA_23 NAGPHGKN_00802 568703.LGG_02860 7.03e-213 587.0 COG3001@1|root,COG3001@2|Bacteria,1U79A@1239|Firmicutes,4HAZS@91061|Bacilli,3F3RK@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase enzyme family - - - - - - - - - - - - Fructosamin_kin NAGPHGKN_00803 568703.LGG_02861 7.69e-171 477.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran NAGPHGKN_00804 568703.LGG_02862 0.0 884.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli,3F4HA@33958|Lactobacillaceae 91061|Bacilli P ABC transporter glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 NAGPHGKN_00805 568703.LGG_02863 0.0 919.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli,3F4HA@33958|Lactobacillaceae 91061|Bacilli P ABC transporter glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 NAGPHGKN_00806 568703.LGG_02864 1.33e-128 365.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,3F6YW@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain ydaF GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017198,GO:0018193,GO:0018209,GO:0019538,GO:0030920,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1990189 - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 NAGPHGKN_00807 568703.LGG_02865 3.53e-134 381.0 COG1300@1|root,COG1300@2|Bacteria,1VFG7@1239|Firmicutes,4IRI6@91061|Bacilli,3F7WH@33958|Lactobacillaceae 91061|Bacilli S Stage II sporulation protein M - - - ko:K06384 - - - - ko00000 - - - SpoIIM NAGPHGKN_00808 568703.LGG_02866 2.85e-215 595.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,3F59F@33958|Lactobacillaceae 91061|Bacilli S ATPase family associated with various cellular activities (AAA) moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 NAGPHGKN_00809 1423816.BACQ01000031_gene1277 2.5e-172 488.0 COG1721@1|root,COG1721@2|Bacteria,1VNZZ@1239|Firmicutes,4IGYV@91061|Bacilli,3F8YE@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 NAGPHGKN_00810 568703.LGG_02868 0.0 1342.0 COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,3F5PB@33958|Lactobacillaceae 91061|Bacilli E Transglutaminase/protease-like homologues yebA - - - - - - - - - - - DUF4129,Transglut_core NAGPHGKN_00811 568703.LGG_02869 4.97e-272 743.0 COG0438@1|root,COG0438@2|Bacteria,1TPHK@1239|Firmicutes,4HAXV@91061|Bacilli,3F5EZ@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 NAGPHGKN_00812 568703.LGG_02872 0.0 886.0 COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,4HFM9@91061|Bacilli,3FBTC@33958|Lactobacillaceae 91061|Bacilli E Fumarase C C-terminus aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 NAGPHGKN_00815 1423816.BACQ01000031_gene1273 1.12e-250 691.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,3F4GN@33958|Lactobacillaceae 91061|Bacilli C Malic enzyme, NAD binding domain mae - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic NAGPHGKN_00816 568703.LGG_02877 1.04e-289 794.0 COG3493@1|root,COG3493@2|Bacteria,1TR97@1239|Firmicutes,4HBS8@91061|Bacilli,3F61N@33958|Lactobacillaceae 91061|Bacilli C 2-hydroxycarboxylate transporter family malP - - ko:K11616 ko02020,map02020 - - - ko00000,ko00001 2.A.24.2 - - 2HCT NAGPHGKN_00817 568703.LGG_02878 0.0 949.0 COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,3F62P@33958|Lactobacillaceae 91061|Bacilli T Single cache domain 3 dpiB - 2.7.13.3 ko:K02476,ko:K11614 ko02020,map02020 M00490 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,SPOB_a,sCache_3_2 NAGPHGKN_00818 568703.LGG_02879 4.99e-154 433.0 COG4565@1|root,COG4565@2|Bacteria,1V3PK@1239|Firmicutes,4HGXB@91061|Bacilli,3F702@33958|Lactobacillaceae 91061|Bacilli KT cheY-homologous receiver domain malR - - ko:K02475,ko:K11615 ko02020,map02020 M00490 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_11,Response_reg NAGPHGKN_00819 568703.LGG_02880 1.43e-123 352.0 29Q7E@1|root,30B6F@2|Bacteria,1U7MH@1239|Firmicutes,4IHIP@91061|Bacilli,3F9WQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00820 1545702.LACWKB8_0421 3.32e-150 431.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,3F4Z6@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C NAGPHGKN_00822 568703.LGG_02881 1.96e-192 535.0 COG2084@1|root,COG2084@2|Bacteria,1U5HC@1239|Firmicutes,4IF86@91061|Bacilli,3F5Y9@33958|Lactobacillaceae 91061|Bacilli I NAD binding domain of 6-phosphogluconate dehydrogenase - - - - - - - - - - - - NAD_binding_2 NAGPHGKN_00823 568703.LGG_02882 3.93e-90 264.0 29NYR@1|root,309WU@2|Bacteria,1U5V4@1239|Firmicutes,4IFIS@91061|Bacilli,3F6J0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00824 568703.LGG_02883 4.52e-169 471.0 COG0518@1|root,COG0518@2|Bacteria,1UAH0@1239|Firmicutes,4IS2F@91061|Bacilli,3FBR7@33958|Lactobacillaceae 91061|Bacilli F Glutamine amidotransferase class-I - - - - - - - - - - - - GATase NAGPHGKN_00825 568703.LGG_02884 7.89e-216 596.0 COG0826@1|root,COG0826@2|Bacteria,1TPCZ@1239|Firmicutes,4HC7A@91061|Bacilli,3F4I6@33958|Lactobacillaceae 91061|Bacilli O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity - - - - - - - - - - - - - NAGPHGKN_00827 568703.LGG_02906 3.77e-217 599.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3V8@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs2 - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N NAGPHGKN_00828 568703.LGG_02907 2.32e-233 640.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta - - - ko:K06889 - - - - ko00000 - - - DLH,FSH1,Hydrolase_4 NAGPHGKN_00829 568703.LGG_02908 9.48e-237 650.0 COG0657@1|root,COG0657@2|Bacteria,1V2AW@1239|Firmicutes,4HU2V@91061|Bacilli,3F3N7@33958|Lactobacillaceae 91061|Bacilli I Carboxylesterase family lipA - - - - - - - - - - - Abhydrolase_3 NAGPHGKN_00830 568703.LGG_02909 1.75e-275 753.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,3F448@33958|Lactobacillaceae 91061|Bacilli C mannitol-1-phosphate 5-dehydrogenase activity mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C NAGPHGKN_00831 568703.LGG_02910 5.35e-102 295.0 COG4668@1|root,COG4668@2|Bacteria,1V77P@1239|Firmicutes,4HIM2@91061|Bacilli,3F6EP@33958|Lactobacillaceae 91061|Bacilli G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane mtlF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02798 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2 NAGPHGKN_00832 568703.LGG_02911 0.0 1295.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,3F561@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB NAGPHGKN_00833 568703.LGG_02912 0.0 1150.0 COG2213@1|root,COG2213@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,3F52S@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit mtlA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIC,PTS_IIB NAGPHGKN_00834 568703.LGG_02913 2.92e-170 475.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,3F3NR@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso NAGPHGKN_00835 568703.LGG_02914 2.23e-191 530.0 COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,3F49K@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 NAGPHGKN_00836 568703.LGG_02915 7.2e-60 184.0 29PY5@1|root,30AWK@2|Bacteria,1U774@1239|Firmicutes,4IH1Y@91061|Bacilli,3F926@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00837 568703.LGG_02916 1.29e-25 95.5 2BZTI@1|root,302JZ@2|Bacteria,1U8EV@1239|Firmicutes,4IICR@91061|Bacilli,3FAWN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00838 568703.LGG_02917 1.23e-175 490.0 2E9FK@1|root,333NY@2|Bacteria,1VGHT@1239|Firmicutes,4HP5Z@91061|Bacilli,3F7UD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00839 568703.LGG_02918 2.08e-283 774.0 COG1476@1|root,COG2856@1|root,COG1476@2|Bacteria,COG2856@2|Bacteria,1TSEK@1239|Firmicutes,4HBGW@91061|Bacilli,3F5TB@33958|Lactobacillaceae 91061|Bacilli K IrrE N-terminal-like domain - - - - - - - - - - - - HTH_3,Peptidase_M78 NAGPHGKN_00840 568703.LGG_02919 1.77e-194 546.0 COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,4HG99@91061|Bacilli,3F5MV@33958|Lactobacillaceae 91061|Bacilli M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family hlyD3 - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 NAGPHGKN_00841 568703.LGG_02920 2.05e-162 454.0 COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HFUH@91061|Bacilli,3F4CA@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_00842 568703.LGG_02921 3.88e-265 728.0 COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HBY9@91061|Bacilli,3F5FN@33958|Lactobacillaceae 91061|Bacilli V MacB-like periplasmic core domain yknZ - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD NAGPHGKN_00843 1423747.BAMJ01000053_gene2145 4.41e-113 336.0 COG0604@1|root,COG0604@2|Bacteria,1VZMF@1239|Firmicutes,4HY0D@91061|Bacilli,3F5Z3@33958|Lactobacillaceae 91061|Bacilli C nadph quinone reductase - - - - - - - - - - - - ADH_zinc_N,ADH_zinc_N_2 NAGPHGKN_00844 1423806.JCM15457_1152 3.85e-94 285.0 COG1396@1|root,COG1396@2|Bacteria,1U4VN@1239|Firmicutes,4IPPT@91061|Bacilli,3FBDK@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3 NAGPHGKN_00845 797515.HMPREF9103_03153 2.91e-39 136.0 2CARX@1|root,34BQY@2|Bacteria,1VYYP@1239|Firmicutes,4HYXX@91061|Bacilli,3F7EH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Polyketide_cyc2 NAGPHGKN_00846 568703.LGG_02922 4.23e-237 659.0 2DKMH@1|root,309XQ@2|Bacteria,1U5WE@1239|Firmicutes,4IFK1@91061|Bacilli,3F6MD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00847 568703.LGG_02923 0.0 2439.0 COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1VE5U@1239|Firmicutes,4ITNN@91061|Bacilli,3FBXI@33958|Lactobacillaceae 91061|Bacilli M Leucine rich repeats (6 copies) - - - - - - - - - - - - Gram_pos_anchor,LRR_5 NAGPHGKN_00848 568703.LGG_02923 8.37e-308 935.0 COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1VE5U@1239|Firmicutes,4ITNN@91061|Bacilli,3FBXI@33958|Lactobacillaceae 91061|Bacilli M Leucine rich repeats (6 copies) - - - - - - - - - - - - Gram_pos_anchor,LRR_5 NAGPHGKN_00849 568703.LGG_02924 1.58e-285 779.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,3F4TW@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase mtnE - - ko:K08969 ko00270,ko01100,map00270,map01100 M00034 R07396 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 NAGPHGKN_00850 568703.LGG_02925 5.63e-180 501.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,3F4ND@33958|Lactobacillaceae 91061|Bacilli S Carbon-nitrogen hydrolase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase NAGPHGKN_00851 568703.LGG_02926 9e-191 530.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HD2T@91061|Bacilli,3F632@33958|Lactobacillaceae 91061|Bacilli M NLPA lipoprotein - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 NAGPHGKN_00854 1231336.L248_0573 1.22e-76 235.0 COG5340@1|root,COG5340@2|Bacteria,1U65Z@1239|Firmicutes,4IFW0@91061|Bacilli,3F75B@33958|Lactobacillaceae 91061|Bacilli K Psort location Cytoplasmic, score - - - - - - - - - - - - - NAGPHGKN_00855 568703.LGG_02928 4.1e-251 690.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,4HC8K@91061|Bacilli,3F4E4@33958|Lactobacillaceae 91061|Bacilli C dehydrogenase ypjH - - ko:K08317 - - - - ko00000,ko01000 - - - Fe-ADH NAGPHGKN_00858 568703.LGG_02931 2.84e-284 777.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,3FC42@33958|Lactobacillaceae 91061|Bacilli E Peptidase family M20/M25/M40 amd - - - - - - - - - - - M20_dimer,Peptidase_M20 NAGPHGKN_00859 568703.LGG_02932 1.8e-105 305.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,3F706@33958|Lactobacillaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 NAGPHGKN_00860 568703.LGG_02933 3.65e-173 484.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,3F4XE@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE NAGPHGKN_00862 568703.LGG_02935 6.61e-41 135.0 2BHN3@1|root,32BQX@2|Bacteria,1U791@1239|Firmicutes,4IH3V@91061|Bacilli,3F94X@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00863 568703.LGG_02936 0.0 964.0 COG1132@1|root,COG1132@2|Bacteria,1V08F@1239|Firmicutes,4HTAU@91061|Bacilli,3F517@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NAGPHGKN_00864 568703.LGG_02937 0.0 1239.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,3F454@33958|Lactobacillaceae 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc NAGPHGKN_00865 568703.LGG_02938 0.0 877.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,3F3WA@33958|Lactobacillaceae 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N NAGPHGKN_00866 568703.LGG_02940 3.01e-177 494.0 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli,3F5WG@33958|Lactobacillaceae 91061|Bacilli S R3H domain protein jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H NAGPHGKN_00867 568703.LGG_02941 8.28e-182 508.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,3F3SD@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP NAGPHGKN_00868 568703.LGG_02942 1.56e-78 233.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,3F6GS@33958|Lactobacillaceae 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P NAGPHGKN_00871 543734.LCABL_31270 3.26e-23 88.6 COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,3F81W@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 NAGPHGKN_00872 568703.LGG_00001 0.0 883.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,3F3YA@33958|Lactobacillaceae 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N NAGPHGKN_00873 568703.LGG_00002 7.18e-149 428.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,3F3ZQ@33958|Lactobacillaceae 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 NAGPHGKN_00874 568703.LGG_00002 5.68e-55 181.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,3F3ZQ@33958|Lactobacillaceae 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 NAGPHGKN_00876 568703.LGG_00003 2.87e-43 140.0 COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,4HNMC@91061|Bacilli,3F803@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein YaaA yaaA - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 NAGPHGKN_00877 568703.LGG_00004 3.29e-258 709.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,3F3Q1@33958|Lactobacillaceae 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N NAGPHGKN_00878 568703.LGG_00005 0.0 1293.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,3F48M@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim NAGPHGKN_00879 568703.LGG_00006 0.0 1688.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,3F3YM@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV NAGPHGKN_00880 568703.LGG_00010 6.04e-12 62.0 COG0629@1|root,COG0629@2|Bacteria,1W7D7@1239|Firmicutes,4I45R@91061|Bacilli,3F9K0@33958|Lactobacillaceae 91061|Bacilli L Single-strand binding protein family - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB NAGPHGKN_00884 543734.LCABL_00070 5.66e-08 52.8 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,3F4M3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC NAGPHGKN_00885 568703.LGG_00010 8.99e-99 286.0 COG0629@1|root,COG0629@2|Bacteria,1W7D7@1239|Firmicutes,4I45R@91061|Bacilli,3F9K0@33958|Lactobacillaceae 91061|Bacilli L Single-strand binding protein family - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB NAGPHGKN_00886 568703.LGG_00011 2.26e-64 196.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,3F6ZY@33958|Lactobacillaceae 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 NAGPHGKN_00887 568703.LGG_00012 4.51e-127 362.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,3F66N@33958|Lactobacillaceae 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB NAGPHGKN_00888 1423732.BALS01000057_gene2844 3.26e-48 154.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,3F7CY@33958|Lactobacillaceae 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 NAGPHGKN_00889 568703.LGG_00015 5.33e-119 340.0 COG0693@1|root,COG0693@2|Bacteria,1V3I7@1239|Firmicutes,4HFNG@91061|Bacilli,3FC7V@33958|Lactobacillaceae 91061|Bacilli S DJ-1/PfpI family yfkM - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI NAGPHGKN_00890 568703.LGG_00016 0.0 971.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,3F5E6@33958|Lactobacillaceae 91061|Bacilli C Cytochrome bd terminal oxidase subunit I cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I NAGPHGKN_00891 568703.LGG_00017 2.05e-233 643.0 COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,4H9KF@91061|Bacilli,3F3ZH@33958|Lactobacillaceae 91061|Bacilli C Cytochrome bd terminal oxidase subunit II - - - - - - - - - - - - Cyt_bd_oxida_II NAGPHGKN_00892 568703.LGG_00018 7.17e-39 129.0 2B5YU@1|root,31YUW@2|Bacteria,1U6T8@1239|Firmicutes,4IGM0@91061|Bacilli,3F8G7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00893 568703.LGG_00021 7.49e-138 392.0 COG1266@1|root,COG1266@2|Bacteria,1VFRX@1239|Firmicutes,4HRQQ@91061|Bacilli,3F4Q0@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity XK27_07085 - - ko:K07052 - - - - ko00000 - - - Abi NAGPHGKN_00894 568703.LGG_00025 1.95e-107 314.0 COG0842@1|root,COG0842@2|Bacteria,1VAB2@1239|Firmicutes 1239|Firmicutes V Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13 - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane NAGPHGKN_00895 568703.LGG_00028 9.5e-209 578.0 COG1131@1|root,COG1131@2|Bacteria,1UHTY@1239|Firmicutes,4ISIK@91061|Bacilli,3FBTX@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_00896 568703.LGG_00029 9.89e-243 669.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,3F779@33958|Lactobacillaceae 91061|Bacilli P Ammonium Transporter Family - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp NAGPHGKN_00897 568703.LGG_00030 1.37e-269 737.0 COG2072@1|root,COG2072@2|Bacteria,1TS9X@1239|Firmicutes,4HC9P@91061|Bacilli,3F60T@33958|Lactobacillaceae 91061|Bacilli P Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_3 NAGPHGKN_00898 568703.LGG_00031 3.23e-204 576.0 COG3942@1|root,COG4942@1|root,COG3942@2|Bacteria,COG4942@2|Bacteria,1VCXB@1239|Firmicutes,4HMCB@91061|Bacilli,3F4ZY@33958|Lactobacillaceae 91061|Bacilli D CHAP domain p40 - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - CHAP NAGPHGKN_00899 568703.LGG_00032 0.0 1552.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,3F4HF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease ylbB - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD NAGPHGKN_00900 568703.LGG_00033 3.54e-165 462.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,3F3YU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_00901 568703.LGG_00034 6.57e-125 356.0 COG1309@1|root,COG1309@2|Bacteria,1VI1M@1239|Firmicutes,4HPZV@91061|Bacilli,3F530@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator - - - - - - - - - - - - TetR_C_8,TetR_N NAGPHGKN_00902 568703.LGG_00035 2.94e-195 541.0 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,3F3ZW@33958|Lactobacillaceae 91061|Bacilli G Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 NAGPHGKN_00903 568703.LGG_00036 2.32e-60 186.0 29PRI@1|root,30APR@2|Bacteria,1U6YE@1239|Firmicutes,4IGSK@91061|Bacilli,3F8Q9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00904 568703.LGG_00037 1.58e-164 462.0 COG0730@1|root,COG0730@2|Bacteria,1VR9G@1239|Firmicutes,4HV4W@91061|Bacilli,3F3TR@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE NAGPHGKN_00905 568703.LGG_00038 8.48e-134 380.0 COG3548@1|root,COG3548@2|Bacteria,1V803@1239|Firmicutes,4IRHS@91061|Bacilli,3F6KM@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 NAGPHGKN_00906 568703.LGG_00039 1.86e-146 412.0 COG0110@1|root,COG0110@2|Bacteria,1TQQB@1239|Firmicutes,4HG1G@91061|Bacilli,3FC9A@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase lacA - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac NAGPHGKN_00907 568703.LGG_00040 7.34e-72 216.0 29Q91@1|root,30B85@2|Bacteria,1U7Q9@1239|Firmicutes,4IHMK@91061|Bacilli,3FA0E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00909 568703.LGG_00041 0.0 987.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 NAGPHGKN_00910 568703.LGG_00042 1.7e-142 402.0 COG2364@1|root,COG2364@2|Bacteria,1VQW3@1239|Firmicutes,4HV4F@91061|Bacilli,3F64W@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - NAGPHGKN_00911 568703.LGG_00043 3.12e-111 321.0 29Q95@1|root,30B89@2|Bacteria,1U7QD@1239|Firmicutes,4IHMQ@91061|Bacilli,3FA0J@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00912 543734.LCABL_00440 5.38e-68 210.0 2BM2D@1|root,32FJC@2|Bacteria,1U7S8@1239|Firmicutes,4IHPK@91061|Bacilli,3FA3P@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00914 1423816.BACQ01000031_gene1142 5.33e-300 845.0 COG3409@1|root,COG3409@2|Bacteria,1TPV1@1239|Firmicutes,4HCRA@91061|Bacilli,3F5J4@33958|Lactobacillaceae 91061|Bacilli M peptidoglycan-binding domain-containing protein ybfG - - - - - - - - - - - DUF1906,PG_binding_1 NAGPHGKN_00915 568703.LGG_00048 3.24e-158 444.0 COG1296@1|root,COG1296@2|Bacteria,1U49T@1239|Firmicutes,4HDIJ@91061|Bacilli,3F45S@33958|Lactobacillaceae 91061|Bacilli E branched-chain amino acid azlC - - - - - - - - - - - AzlC NAGPHGKN_00916 568703.LGG_00049 1.29e-66 202.0 COG4392@1|root,COG4392@2|Bacteria,1VH9Q@1239|Firmicutes,4HNDZ@91061|Bacilli,3F7IU@33958|Lactobacillaceae 91061|Bacilli S Branched-chain amino acid transport protein (AzlD) azlD - - - - - - - - - - - AzlD NAGPHGKN_00917 568703.LGG_00050 0.0 1236.0 COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,4HCXR@91061|Bacilli,3F4FZ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 2 family - - 3.2.1.31 ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 M00014,M00076,M00077,M00078,M00129 R01478,R04979,R07818,R08127,R08260,R10830 RC00055,RC00171,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N NAGPHGKN_00918 568703.LGG_00051 0.0 2721.0 COG1409@1|root,COG5520@1|root,COG1409@2|Bacteria,COG5520@2|Bacteria,1UY9C@1239|Firmicutes,4IQ7Q@91061|Bacilli,3FBGD@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolase family 59 - - - - - - - - - - - - FIVAR,Glyco_hydro_59 NAGPHGKN_00919 568703.LGG_00052 5.06e-152 427.0 COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,3F6AY@33958|Lactobacillaceae 91061|Bacilli G KDPG and KHG aldolase eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase NAGPHGKN_00920 568703.LGG_00053 6.08e-227 625.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,4HBH6@91061|Bacilli,3F4FT@33958|Lactobacillaceae 91061|Bacilli G pfkB family carbohydrate kinase kdgK - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB NAGPHGKN_00921 1423816.BACQ01000031_gene1184 0.0 958.0 COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,4HCGI@91061|Bacilli,3F4QN@33958|Lactobacillaceae 91061|Bacilli G glucuronate isomerase uxaC - 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 - - - UxaC NAGPHGKN_00922 568703.LGG_00056 4.1e-276 753.0 COG1312@1|root,COG1312@2|Bacteria,1TP5F@1239|Firmicutes,4H9UR@91061|Bacilli,3F4UF@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the dehydration of D-mannonate uxuA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008198,GO:0008927,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019585,GO:0019752,GO:0030145,GO:0032787,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0071704,GO:0072329,GO:1901575 4.2.1.8 ko:K01686 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 - - - UxuA NAGPHGKN_00923 568703.LGG_00057 0.0 1097.0 COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,4HBQ9@91061|Bacilli,3F3XU@33958|Lactobacillaceae 91061|Bacilli G Mannitol dehydrogenase C-terminal domain uxuB - 1.1.1.57 ko:K00040 ko00040,ko01100,map00040,map01100 M00061 R02454 RC00085 ko00000,ko00001,ko00002,ko01000 - - - Mannitol_dh,Mannitol_dh_C NAGPHGKN_00924 797515.HMPREF9103_02208 0.0 917.0 COG5520@1|root,COG5520@2|Bacteria,1URVQ@1239|Firmicutes,4HE4Z@91061|Bacilli,3F5VR@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolase family 30 TIM-barrel domain - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - Glyco_hydro_30,Glyco_hydro_30C NAGPHGKN_00925 568703.LGG_00058 6.58e-293 803.0 COG2211@1|root,COG2211@2|Bacteria,1V3NJ@1239|Firmicutes,4HTUC@91061|Bacilli,3F4KD@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator - - - - - - - - - - - - MFS_1 NAGPHGKN_00926 568703.LGG_00059 1.9e-163 457.0 COG1802@1|root,COG1802@2|Bacteria,1V3SB@1239|Firmicutes,4HGG8@91061|Bacilli,3F69H@33958|Lactobacillaceae 91061|Bacilli K FCD domain kdgR - - - - - - - - - - - FCD,GntR NAGPHGKN_00927 568703.LGG_00060 1.74e-242 668.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,4HT5E@91061|Bacilli,3FC26@33958|Lactobacillaceae 91061|Bacilli G pfkB family carbohydrate kinase kdgK - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB NAGPHGKN_00928 568703.LGG_00061 0.0 1675.0 COG5520@1|root,COG5520@2|Bacteria,1UKTQ@1239|Firmicutes,4HEXZ@91061|Bacilli,3F5BP@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolase family 59 - - - - - - - - - - - - Glyco_hydro_59 NAGPHGKN_00929 568703.LGG_00062 9.4e-76 226.0 2E9Y3@1|root,3343R@2|Bacteria,1VFF0@1239|Firmicutes,4HPUY@91061|Bacilli,3F8BC@33958|Lactobacillaceae 91061|Bacilli - - ps105 - - - - - - - - - - - - NAGPHGKN_00930 568703.LGG_00063 6.82e-52 166.0 COG3576@1|root,COG3576@2|Bacteria,1VGE7@1239|Firmicutes,4HNE7@91061|Bacilli,3F6YB@33958|Lactobacillaceae 91061|Bacilli S pyridoxamine 5-phosphate - - - - - - - - - - - - Putative_PNPOx NAGPHGKN_00931 568703.LGG_00064 1e-306 838.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 NAGPHGKN_00932 568703.LGG_00065 2.81e-279 763.0 COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,4HI9S@91061|Bacilli 91061|Bacilli I Alpha beta hydrolase - - 3.1.1.83 ko:K14731 ko00903,ko00930,ko01220,map00903,map00930,map01220 - R03751,R06390,R06391,R06392,R06393 RC00713,RC00983,RC01505 ko00000,ko00001,ko01000 - - - Abhydrolase_3 NAGPHGKN_00933 568703.LGG_00066 9.32e-154 432.0 COG1309@1|root,COG1309@2|Bacteria,1VFZP@1239|Firmicutes,4HYAN@91061|Bacilli,3F872@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N NAGPHGKN_00935 568703.LGG_00068 0.0 1511.0 COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4HBM6@91061|Bacilli,3FCCY@33958|Lactobacillaceae 91061|Bacilli S MMPL family ydgH - - ko:K06994 - - - - ko00000 - - - MMPL NAGPHGKN_00936 568703.LGG_00069 3.73e-137 388.0 COG1309@1|root,COG1309@2|Bacteria,1V95E@1239|Firmicutes,4HH9M@91061|Bacilli,3F6ZH@33958|Lactobacillaceae 91061|Bacilli K Tetracycline repressor, C-terminal all-alpha domain - - - ko:K22106 - - - - ko00000,ko03000 - - - TetR_C_10,TetR_N NAGPHGKN_00937 1423816.BACQ01000031_gene1168 2.75e-157 443.0 COG0730@1|root,COG0730@2|Bacteria,1VPY2@1239|Firmicutes,4IQZ2@91061|Bacilli,3F7BY@33958|Lactobacillaceae 91061|Bacilli S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE NAGPHGKN_00938 568703.LGG_00071 1.21e-309 844.0 COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,4HBV3@91061|Bacilli,3F4YC@33958|Lactobacillaceae 91061|Bacilli F Amidohydrolase family - - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 NAGPHGKN_00939 568703.LGG_00072 1.3e-89 264.0 2B1UF@1|root,31UAF@2|Bacteria,1V79N@1239|Firmicutes,4IF71@91061|Bacilli,3F79B@33958|Lactobacillaceae 91061|Bacilli S An automated process has identified a potential problem with this gene model - - - - - - - - - - - - - NAGPHGKN_00940 568703.LGG_00073 1.68e-191 532.0 arCOG09719@1|root,2Z7NA@2|Bacteria,1TSE4@1239|Firmicutes,4HE46@91061|Bacilli,3F5Z4@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3100) - - - - - - - - - - - - DUF3100 NAGPHGKN_00942 568703.LGG_00075 1.37e-142 404.0 COG1174@1|root,COG1174@2|Bacteria,1TQ5C@1239|Firmicutes,4HAVM@91061|Bacilli,3F51B@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component opuCD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iYO844.BSU33800 BPD_transp_1 NAGPHGKN_00943 568703.LGG_00076 1.96e-225 620.0 COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HARV@91061|Bacilli,3F420@33958|Lactobacillaceae 91061|Bacilli M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) opuCC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12835 OpuAC NAGPHGKN_00944 568703.LGG_00077 2.13e-136 387.0 COG1174@1|root,COG1174@2|Bacteria,1TSX8@1239|Firmicutes,4HC1D@91061|Bacilli,3F4EM@33958|Lactobacillaceae 91061|Bacilli E ABC transporter permease opuCB - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 NAGPHGKN_00945 568703.LGG_00078 7.45e-279 764.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,3F55H@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein opuCA - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12845,iYO844.BSU33730 ABC_tran,CBS NAGPHGKN_00946 568703.LGG_00082 0.0 1124.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4T3@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase NAGPHGKN_00947 543734.LCABL_00680 1.04e-45 147.0 COG2608@1|root,COG2608@2|Bacteria,1VFJ8@1239|Firmicutes,4HNY2@91061|Bacilli,3F830@33958|Lactobacillaceae 91061|Bacilli P Heavy-metal-associated domain copZ - - - - - - - - - - - HMA NAGPHGKN_00948 568703.LGG_00084 6.78e-132 374.0 COG0783@1|root,COG0783@2|Bacteria,1VB1X@1239|Firmicutes,4HMJG@91061|Bacilli,3F4SN@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Dps family dpsB - - - - - - - - - - - Ferritin NAGPHGKN_00949 568703.LGG_00085 2.13e-150 423.0 COG0664@1|root,COG0664@2|Bacteria,1UZT0@1239|Firmicutes,4HFR2@91061|Bacilli,3FBKF@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, cAMP Regulatory protein flp - - ko:K21562 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding NAGPHGKN_00951 568703.LGG_00089 2.81e-201 558.0 COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,4HPR4@91061|Bacilli,3F5HF@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi NAGPHGKN_00952 1158602.I590_01304 0.0 877.0 COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,4B1M1@81852|Enterococcaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02770,ko:K02794,ko:K02795 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - PTS_EIIC,PTS_IIB NAGPHGKN_00953 568703.LGG_00092 1.99e-104 301.0 COG1762@1|root,COG1762@2|Bacteria,1V7JV@1239|Firmicutes,4HJ0E@91061|Bacilli,3F73T@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 frvA - 2.7.1.202 ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 NAGPHGKN_00954 568703.LGG_00093 0.0 1693.0 COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HBC7@91061|Bacilli,3F4XS@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 38 N-terminal domain mngB - 3.2.1.170 ko:K15524 - - - - ko00000,ko01000 - GH38 - Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C NAGPHGKN_00955 568703.LGG_00094 1.01e-179 501.0 COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,4HIBB@91061|Bacilli,3F6SV@33958|Lactobacillaceae 91061|Bacilli K SIS domain - - - - - - - - - - - - HTH_6,SIS NAGPHGKN_00956 568703.LGG_00095 0.0 879.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,3FC7B@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.21,3.2.1.85,3.2.1.86 ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03256,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 NAGPHGKN_00957 568703.LGG_00096 5.67e-200 555.0 COG1940@1|root,COG1940@2|Bacteria,1UZ80@1239|Firmicutes,4HD5J@91061|Bacilli,3F5ZR@33958|Lactobacillaceae 91061|Bacilli GK ROK family bglK_1 - - - - - - - - - - - ROK NAGPHGKN_00959 568703.LGG_00098 2.89e-182 508.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,3F50S@33958|Lactobacillaceae 91061|Bacilli E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA NAGPHGKN_00960 568703.LGG_00099 7.93e-290 791.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,3F4DT@33958|Lactobacillaceae 91061|Bacilli E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22640 PALP NAGPHGKN_00961 568703.LGG_00100 2.84e-136 386.0 COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HN68@91061|Bacilli,3F4B6@33958|Lactobacillaceae 91061|Bacilli E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI NAGPHGKN_00962 568703.LGG_00101 2.09e-170 477.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HDZQ@91061|Bacilli,3F5AK@33958|Lactobacillaceae 91061|Bacilli E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS NAGPHGKN_00963 568703.LGG_00102 6.58e-231 637.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,3F50X@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 NAGPHGKN_00965 568703.LGG_00104 0.0 1088.0 COG0477@1|root,COG2211@1|root,COG0477@2|Bacteria,COG2211@2|Bacteria,1TPV3@1239|Firmicutes,4HCJN@91061|Bacilli,3F5DE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 NAGPHGKN_00966 568703.LGG_00105 6.02e-143 403.0 COG1309@1|root,COG1309@2|Bacteria,1V9ST@1239|Firmicutes,4HP6S@91061|Bacilli,3F5J7@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N NAGPHGKN_00967 568703.LGG_00106 8.18e-151 426.0 2BJ44@1|root,32DD4@2|Bacteria,1U7J0@1239|Firmicutes,4IHFT@91061|Bacilli,3F9SG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00968 543734.LCABL_00870 1.39e-198 561.0 COG1277@1|root,COG1277@2|Bacteria,1VKEJ@1239|Firmicutes,4HS6Y@91061|Bacilli,3F7SD@33958|Lactobacillaceae 91061|Bacilli S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - NAGPHGKN_00969 543734.LCABL_00880 2.35e-136 395.0 2AD8Y@1|root,312XZ@2|Bacteria,1U71Z@1239|Firmicutes,4IGWF@91061|Bacilli,3F8VJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00970 543734.LCABL_00890 5.89e-125 360.0 COG1131@1|root,COG1131@2|Bacteria,1UQMC@1239|Firmicutes,4HE32@91061|Bacilli,3F6CK@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_00972 568703.LGG_00107 2.26e-136 386.0 COG1898@1|root,COG1898@2|Bacteria,1VRRN@1239|Firmicutes 1239|Firmicutes M dTDP-4-dehydrorhamnose 3,5-epimerase - - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom NAGPHGKN_00973 568703.LGG_00108 1.18e-174 488.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,3F3MA@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N NAGPHGKN_00974 568703.LGG_00109 3.74e-210 581.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,3F4UH@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS NAGPHGKN_00975 568703.LGG_00110 6.84e-278 759.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,3F419@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 NAGPHGKN_00976 568703.LGG_00111 1.03e-114 334.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,3F3U0@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep NAGPHGKN_00977 568703.LGG_00112 0.0 872.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,3F3VJ@33958|Lactobacillaceae 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC NAGPHGKN_00979 568703.LGG_00113 8.11e-199 558.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,3F48V@33958|Lactobacillaceae 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 NAGPHGKN_00980 568703.LGG_00114 5.72e-238 654.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,3F4F7@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase NAGPHGKN_00981 568703.LGG_00115 5.83e-251 689.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,3F4S9@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC NAGPHGKN_00982 568703.LGG_00116 8.13e-82 242.0 29PM4@1|root,30AVT@2|Bacteria,1U75Z@1239|Firmicutes,4IH0M@91061|Bacilli,3F90S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00983 568703.LGG_00118 2.62e-95 277.0 COG0494@1|root,COG0494@2|Bacteria,1VK3S@1239|Firmicutes,4IHJ0@91061|Bacilli,3F9X5@33958|Lactobacillaceae 91061|Bacilli L NUDIX domain - - - - - - - - - - - - NUDIX NAGPHGKN_00984 568703.LGG_00119 5.16e-192 535.0 COG0697@1|root,COG0697@2|Bacteria,1V86F@1239|Firmicutes,4HJWZ@91061|Bacilli,3F4CV@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA NAGPHGKN_00986 568703.LGG_01153 2.24e-64 209.0 COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,4HEX8@91061|Bacilli,3F5HS@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_5,DDE_Tnp_1 NAGPHGKN_00987 568703.LGG_01959 2.4e-137 389.0 COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,4HEX8@91061|Bacilli,3F5HS@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_5,DDE_Tnp_1 NAGPHGKN_00988 1423734.JCM14202_3924 1.95e-78 241.0 COG1309@1|root,COG1309@2|Bacteria,1U7HQ@1239|Firmicutes,4IHEB@91061|Bacilli,3F9Q8@33958|Lactobacillaceae 91061|Bacilli K Tetracyclin repressor, C-terminal all-alpha domain - - - - - - - - - - - - TetR_C,TetR_N NAGPHGKN_00989 626369.HMPREF0446_01301 3.71e-68 222.0 COG0842@1|root,COG0842@2|Bacteria,1V08Z@1239|Firmicutes 1239|Firmicutes V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 NAGPHGKN_00990 626369.HMPREF0446_01300 4.01e-99 296.0 COG0842@1|root,COG0842@2|Bacteria,1TR3T@1239|Firmicutes,4IQWV@91061|Bacilli 91061|Bacilli P ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane NAGPHGKN_00991 866775.HMPREF9243_1924 3.17e-126 370.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4IPMF@91061|Bacilli,27E06@186827|Aerococcaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 NAGPHGKN_00992 568703.LGG_00121 0.0 1284.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,3F3TY@33958|Lactobacillaceae 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 NAGPHGKN_00993 568703.LGG_00122 4.7e-98 285.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,3F68P@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N NAGPHGKN_00994 568703.LGG_00123 3.57e-314 858.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,3F4MW@33958|Lactobacillaceae 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C NAGPHGKN_00995 568703.LGG_00124 3.05e-282 771.0 2CC2J@1|root,309K5@2|Bacteria,1U598@1239|Firmicutes,4IF0I@91061|Bacilli,3F58S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_00996 568703.LGG_00125 0.0 1221.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts32BC - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NAGPHGKN_00997 568703.LGG_00126 8.75e-209 578.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,3F4T1@33958|Lactobacillaceae 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 NAGPHGKN_00998 568703.LGG_00127 8.98e-253 693.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4HAHJ@91061|Bacilli,3FB4D@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) - - 4.2.1.126 ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - DUF871 NAGPHGKN_00999 568703.LGG_00128 6.9e-200 554.0 COG1737@1|root,COG1737@2|Bacteria,1TPIX@1239|Firmicutes,4HBJA@91061|Bacilli,3F5WQ@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family yleF - - - - - - - - - - - HTH_6,SIS NAGPHGKN_01000 568703.LGG_00129 8.13e-137 387.0 COG1309@1|root,COG1309@2|Bacteria,1V9XI@1239|Firmicutes,4HJ7Q@91061|Bacilli,3F77G@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator C-terminal region - - - - - - - - - - - - TetR_C_8,TetR_N NAGPHGKN_01001 568703.LGG_00130 9.01e-164 458.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,3F3YU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_01002 568703.LGG_00131 0.0 1613.0 COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,3F4HF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease ylbB - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD NAGPHGKN_01003 568703.LGG_00132 2.94e-264 722.0 COG2159@1|root,COG2159@2|Bacteria,1TRAY@1239|Firmicutes,4HFH2@91061|Bacilli,3F485@33958|Lactobacillaceae 91061|Bacilli S Amidohydrolase - - 4.1.1.52 ko:K22213 - - - - ko00000,ko01000 - - - Amidohydro_2 NAGPHGKN_01004 568703.LGG_00133 0.0 863.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,3F3RQ@33958|Lactobacillaceae 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt NAGPHGKN_01005 568703.LGG_00135 0.0 1174.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4T3@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase NAGPHGKN_01006 568703.LGG_00136 4.21e-72 217.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HFYU@91061|Bacilli,3FB53@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor cadC5 - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_5 NAGPHGKN_01007 568703.LGG_00137 7.11e-260 716.0 COG0477@1|root,COG2814@2|Bacteria,1UZKT@1239|Firmicutes,4HDHS@91061|Bacilli,3F4QJ@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily pmrB - - - - - - - - - - - MFS_1 NAGPHGKN_01008 543734.LCABL_01180 1.34e-193 545.0 COG1476@1|root,COG1476@2|Bacteria,1TNYC@1239|Firmicutes,4HF5V@91061|Bacilli,3F58D@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 NAGPHGKN_01009 543734.LCABL_01190 6.52e-36 122.0 2E3AZ@1|root,32YAF@2|Bacteria,1VF37@1239|Firmicutes,4HP14@91061|Bacilli,3F8CH@33958|Lactobacillaceae 91061|Bacilli S Phospholipase_D-nuclease N-terminal - - - - - - - - - - - - PLDc_N NAGPHGKN_01010 543734.LCABL_01200 5.45e-154 440.0 COG1131@1|root,COG1131@2|Bacteria,1TQEV@1239|Firmicutes,4HBHF@91061|Bacilli,3F612@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yxlF - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 NAGPHGKN_01011 543734.LCABL_01210 3.78e-131 377.0 COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,4HIS1@91061|Bacilli,3F5JZ@33958|Lactobacillaceae 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 NAGPHGKN_01012 568703.LGG_00138 0.0 1483.0 COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,4HBIY@91061|Bacilli,3F435@33958|Lactobacillaceae 91061|Bacilli F Ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD NAGPHGKN_01013 568703.LGG_00139 1.43e-38 134.0 2E7NX@1|root,33B9D@2|Bacteria,1VPN2@1239|Firmicutes,4HS0V@91061|Bacilli,3F7ZV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01014 568703.LGG_00139 3.4e-64 200.0 2E7NX@1|root,33B9D@2|Bacteria,1VPN2@1239|Firmicutes,4HS0V@91061|Bacilli,3F7ZV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01015 568703.LGG_00142 2.48e-142 409.0 COG1476@1|root,COG1476@2|Bacteria,1V6QF@1239|Firmicutes,4HIIT@91061|Bacilli,3F7M5@33958|Lactobacillaceae 91061|Bacilli K Bacteriophage CI repressor helix-turn-helix domain - - - - - - - - - - - - DUF3955,HTH_3 NAGPHGKN_01016 568703.LGG_00145 2e-238 655.0 COG0671@1|root,COG0671@2|Bacteria,1V7AD@1239|Firmicutes,4HJB7@91061|Bacilli,3F4Q4@33958|Lactobacillaceae 91061|Bacilli I PAP2 superfamily yveB - - - - - - - - - - - PAP2 NAGPHGKN_01017 568703.LGG_00146 2.16e-265 726.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HDUZ@91061|Bacilli,3F3NK@33958|Lactobacillaceae 91061|Bacilli V LD-carboxypeptidase mccF - - - - - - - - - - - Peptidase_S66 NAGPHGKN_01018 568703.LGG_00147 2.67e-56 174.0 29QF0@1|root,30BEB@2|Bacteria,1U7ZU@1239|Firmicutes,4IHX8@91061|Bacilli,3FAD7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01019 568703.LGG_00148 1.15e-261 716.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,3F41Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N NAGPHGKN_01020 568703.LGG_00149 1.06e-53 168.0 296ET@1|root,2ZTQF@2|Bacteria,1W3JW@1239|Firmicutes,4I0TZ@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01021 568703.LGG_00150 1.05e-143 406.0 29PZE@1|root,30AXV@2|Bacteria,1U78T@1239|Firmicutes,4HYEX@91061|Bacilli,3F94M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01022 568703.LGG_00151 7.29e-290 797.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HTQ7@91061|Bacilli,3F5J1@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 NAGPHGKN_01023 568703.LGG_00154 4.54e-111 320.0 28PR5@1|root,2ZCD3@2|Bacteria,1V3WQ@1239|Firmicutes,4HN4C@91061|Bacilli,3F7UK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01024 568703.LGG_00155 8.02e-255 699.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4H9UD@91061|Bacilli,3F3Z4@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA NAGPHGKN_01025 568703.LGG_00156 4.14e-155 436.0 COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HGB5@91061|Bacilli,3FC96@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C NAGPHGKN_01026 568703.LGG_00157 6.05e-118 337.0 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,3F6RF@33958|Lactobacillaceae 91061|Bacilli L Methyltransferase adaB GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,Methyltransf_1N NAGPHGKN_01027 568703.LGG_00158 6.21e-241 662.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HCIS@91061|Bacilli,3F4US@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhD3 - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C NAGPHGKN_01028 568703.LGG_00159 4.97e-64 196.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F7XZ@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit ptcB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB NAGPHGKN_01029 568703.LGG_00160 1.99e-69 209.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,3FA2W@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit celC - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA NAGPHGKN_01030 568703.LGG_00161 3.35e-111 320.0 2E5MG@1|root,330CD@2|Bacteria,1VE22@1239|Firmicutes,4IRFH@91061|Bacilli,3FBP1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01031 568703.LGG_00162 0.0 882.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HDVN@91061|Bacilli,3FC70@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celD - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC NAGPHGKN_01032 568703.LGG_00163 0.0 989.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 NAGPHGKN_01033 568703.LGG_00164 3.38e-169 473.0 COG2188@1|root,COG2188@2|Bacteria,1V4DC@1239|Firmicutes,4HIDU@91061|Bacilli,3F6TC@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03489 - - - - ko00000,ko03000 - - - GntR,UTRA NAGPHGKN_01034 568703.LGG_00165 9.23e-55 172.0 298HG@1|root,2ZKVW@2|Bacteria,1W538@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - NAGPHGKN_01035 568703.LGG_00166 1.17e-75 226.0 COG3759@1|root,COG3759@2|Bacteria,1VAVU@1239|Firmicutes,4HQHN@91061|Bacilli,3F7NA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1304) - - - ko:K08987 - - - - ko00000 - - - DUF1304 NAGPHGKN_01036 568703.LGG_00167 2.83e-71 215.0 2EGA1@1|root,33A1U@2|Bacteria,1VPXU@1239|Firmicutes,4HS3Y@91061|Bacilli,3F7WK@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1516) - - - - - - - - - - - - DUF1516 NAGPHGKN_01037 568703.LGG_00168 0.0 887.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,3F44D@33958|Lactobacillaceae 91061|Bacilli S permease XK27_07275 - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease NAGPHGKN_01038 568703.LGG_00169 3.44e-70 211.0 COG1416@1|root,COG1416@2|Bacteria,1VEYT@1239|Firmicutes,4HQQN@91061|Bacilli,3FBBQ@33958|Lactobacillaceae 91061|Bacilli S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE NAGPHGKN_01039 568703.LGG_00178 6.44e-239 656.0 COG0346@1|root,COG0346@2|Bacteria,1TP7I@1239|Firmicutes,4H9ND@91061|Bacilli,3F4PB@33958|Lactobacillaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily mhqA - - ko:K15975 - - - - ko00000 - - - Glyoxalase NAGPHGKN_01040 568703.LGG_00179 4.75e-57 177.0 29Q9W@1|root,30B8Z@2|Bacteria,1U7RE@1239|Firmicutes,4IHNS@91061|Bacilli,3FA2D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01041 568703.LGG_00180 9.29e-138 389.0 COG1670@1|root,COG1670@2|Bacteria,1VCN3@1239|Firmicutes,4HKNF@91061|Bacilli,3F7GP@33958|Lactobacillaceae 91061|Bacilli J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins yoaA - - - - - - - - - - - Acetyltransf_3 NAGPHGKN_01042 568703.LGG_00181 0.0 1176.0 2F70X@1|root,33ZGK@2|Bacteria,1VXAH@1239|Firmicutes,4HXTD@91061|Bacilli,3F9HI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01044 568703.LGG_00183 8.2e-177 494.0 2DKUU@1|root,30E2P@2|Bacteria,1V53P@1239|Firmicutes,4HMV7@91061|Bacilli,3FBA0@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL NAGPHGKN_01045 568703.LGG_00184 3.3e-240 662.0 COG4072@1|root,COG4072@2|Bacteria,1VCXS@1239|Firmicutes,4HKJG@91061|Bacilli,3F5HA@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein ynjC - - - - - - - - - - - DUF3324,DUF916 NAGPHGKN_01047 568703.LGG_00186 1.39e-168 482.0 COG3711@1|root,COG3711@2|Bacteria,1VBUE@1239|Firmicutes,4HN8V@91061|Bacilli,3FBAD@33958|Lactobacillaceae 91061|Bacilli L Mga helix-turn-helix domain - - - - - - - - - - - - Mga NAGPHGKN_01048 568703.LGG_00186 4.28e-148 427.0 COG3711@1|root,COG3711@2|Bacteria,1VBUE@1239|Firmicutes,4HN8V@91061|Bacilli,3FBAD@33958|Lactobacillaceae 91061|Bacilli L Mga helix-turn-helix domain - - - - - - - - - - - - Mga NAGPHGKN_01049 568703.LGG_00187 2e-191 536.0 COG3152@1|root,COG3152@2|Bacteria,1VP5A@1239|Firmicutes,4IFSK@91061|Bacilli,3F6XM@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 NAGPHGKN_01050 568703.LGG_00188 9.43e-73 218.0 2C1B3@1|root,302T3@2|Bacteria,1U6JW@1239|Firmicutes,4IGCF@91061|Bacilli,3F821@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01051 568703.LGG_00189 0.0 876.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3NB@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N NAGPHGKN_01052 568703.LGG_00190 1.7e-279 764.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase NAGPHGKN_01053 568703.LGG_00191 3.65e-171 478.0 COG1349@1|root,COG1349@2|Bacteria,1TSV7@1239|Firmicutes,4HD91@91061|Bacilli,3F8GM@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR NAGPHGKN_01054 568703.LGG_00192 0.0 981.0 COG1070@1|root,COG1070@2|Bacteria,1UYIG@1239|Firmicutes,4HUWR@91061|Bacilli,3F9C6@33958|Lactobacillaceae 91061|Bacilli G FGGY family of carbohydrate kinases, C-terminal domain - - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N NAGPHGKN_01055 568703.LGG_00193 9.14e-205 566.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4IQQT@91061|Bacilli,3F64U@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase NAGPHGKN_01056 568703.LGG_00194 1.27e-308 842.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HBAD@91061|Bacilli,3F4Y4@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component - - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT NAGPHGKN_01057 568703.LGG_00195 3.89e-203 561.0 COG0639@1|root,COG0639@2|Bacteria,1V1HN@1239|Firmicutes,4HHQ3@91061|Bacilli,3FCCD@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase superfamily domain pphA - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos NAGPHGKN_01058 568703.LGG_00196 1.39e-174 486.0 COG2231@1|root,COG2231@2|Bacteria,1V4SG@1239|Firmicutes,4HI5U@91061|Bacilli,3F62T@33958|Lactobacillaceae 91061|Bacilli L Base excision DNA repair protein, HhH-GPD family - - - ko:K07457 - - - - ko00000 - - - HhH-GPD NAGPHGKN_01059 568703.LGG_00197 0.0 903.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator bmr3 - - - - - - - - - - - MFS_1 NAGPHGKN_01062 1423732.BALS01000110_gene32 3.47e-112 330.0 2BN5I@1|root,32GSQ@2|Bacteria,1U7WJ@1239|Firmicutes,4IHTY@91061|Bacilli,3FA9G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01064 1423732.BALS01000110_gene31 7.46e-61 193.0 COG1131@1|root,COG1131@2|Bacteria 2|Bacteria V ATPase activity - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_01065 568703.LGG_00198 3.79e-28 102.0 29QMR@1|root,30BMD@2|Bacteria,1U8BI@1239|Firmicutes,4II9I@91061|Bacilli,3FASZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01067 568703.LGG_00200 0.0 1640.0 COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,4HC2J@91061|Bacilli,3F3TZ@33958|Lactobacillaceae 91061|Bacilli G Phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N NAGPHGKN_01068 568703.LGG_00201 0.0 1061.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 NAGPHGKN_01069 1423816.BACQ01000030_gene1065 1.65e-116 340.0 2BFQS@1|root,329JG@2|Bacteria,1TZIV@1239|Firmicutes,4IGKR@91061|Bacilli,3F8FT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01070 568703.LGG_00203 1.92e-149 422.0 2AHJ7@1|root,317WU@2|Bacteria,1U7P7@1239|Firmicutes,4IHKH@91061|Bacilli,3F9Z1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01071 568703.LGG_00204 6.5e-162 454.0 29Q10@1|root,30AZH@2|Bacteria,1U7B5@1239|Firmicutes,4IH65@91061|Bacilli,3F994@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01072 568703.LGG_00205 2.8e-152 428.0 COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,4HDRD@91061|Bacilli,3FC3S@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_01073 568703.LGG_00206 2.2e-97 284.0 29Q9A@1|root,30B8E@2|Bacteria,1U7QJ@1239|Firmicutes,4IHMW@91061|Bacilli,3FA0T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01074 568703.LGG_00207 5.25e-106 306.0 2BFZ1@1|root,329UX@2|Bacteria,1W1ZW@1239|Firmicutes,4I0E0@91061|Bacilli,3F9QT@33958|Lactobacillaceae 91061|Bacilli S NUDIX domain - - - - - - - - - - - - NUDIX NAGPHGKN_01075 568703.LGG_00208 2.66e-271 742.0 COG1537@1|root,COG1537@2|Bacteria,1UPQ9@1239|Firmicutes,4IV8X@91061|Bacilli,3FC0K@33958|Lactobacillaceae 91061|Bacilli S nuclear-transcribed mRNA catabolic process, no-go decay - - - - - - - - - - - - - NAGPHGKN_01076 568703.LGG_00211 0.0 1238.0 COG4529@1|root,COG4529@2|Bacteria,1UZ38@1239|Firmicutes,4HDXC@91061|Bacilli,3F4ZH@33958|Lactobacillaceae 91061|Bacilli S FAD-NAD(P)-binding fnq20 - - - - - - - - - - - NAD_binding_9 NAGPHGKN_01077 568703.LGG_00212 0.0 902.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase nox - 1.6.3.4 ko:K17869 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim NAGPHGKN_01078 568703.LGG_00213 6.18e-150 421.0 29DQI@1|root,300NC@2|Bacteria,1U55V@1239|Firmicutes,4IEX6@91061|Bacilli,3F4UQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01079 568703.LGG_00215 8.84e-274 752.0 COG1512@1|root,COG1512@2|Bacteria,1VHE2@1239|Firmicutes,4HJHN@91061|Bacilli,3F75Q@33958|Lactobacillaceae 91061|Bacilli S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase NAGPHGKN_01080 568703.LGG_00216 2.86e-183 511.0 COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,4HCYJ@91061|Bacilli,3FCAW@33958|Lactobacillaceae 91061|Bacilli S Sulfite exporter TauE/SafE yunE - - ko:K07090 - - - - ko00000 - - - TauE NAGPHGKN_01081 568703.LGG_00217 1.85e-73 221.0 COG4272@1|root,COG4272@2|Bacteria,1VAPQ@1239|Firmicutes,4IRG9@91061|Bacilli,3FBP6@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1634) ywjH - - - - - - - - - - - DUF1634 NAGPHGKN_01082 1423790.BN53_05765 1.47e-07 50.4 29PI4@1|root,30AG9@2|Bacteria,1U6MC@1239|Firmicutes,4IGE7@91061|Bacilli,3F858@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01083 568703.LGG_00219 5.12e-84 251.0 29QKG@1|root,30BK4@2|Bacteria,1U898@1239|Firmicutes,4II73@91061|Bacilli,3FAQ9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01084 568703.LGG_00220 7.43e-69 207.0 29Q8B@1|root,30B7C@2|Bacteria,1U7P0@1239|Firmicutes,4IHK9@91061|Bacilli,3F9YT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01085 568703.LGG_00221 2.23e-107 309.0 COG0716@1|root,COG0716@2|Bacteria,1U7EW@1239|Firmicutes,4IHAT@91061|Bacilli,3F9HX@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin - - - - - - - - - - - - Flavodoxin_1 NAGPHGKN_01086 1423816.BACQ01000030_gene1046 4.57e-49 156.0 2930D@1|root,3270J@2|Bacteria,1USWD@1239|Firmicutes,4IG6X@91061|Bacilli,3F7S4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01087 568703.LGG_00223 4.87e-37 124.0 29QNT@1|root,30BNF@2|Bacteria,1U8D5@1239|Firmicutes,4IIB4@91061|Bacilli,3FAUS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01088 568703.LGG_00225 5.78e-219 605.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,3F4Z6@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C NAGPHGKN_01089 568703.LGG_00226 1.87e-93 272.0 COG3576@1|root,COG3576@2|Bacteria,1V4U5@1239|Firmicutes,4HX4S@91061|Bacilli,3FBB6@33958|Lactobacillaceae 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx NAGPHGKN_01090 568703.LGG_00227 1.55e-51 162.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc NAGPHGKN_01091 568703.LGG_00228 1.68e-116 334.0 COG1302@1|root,COG1302@2|Bacteria,1VN34@1239|Firmicutes,4HRAM@91061|Bacilli,3F8AH@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria - - - - - - - - - - - - - NAGPHGKN_01092 568703.LGG_00229 1.32e-39 131.0 29QCQ@1|root,30BBZ@2|Bacteria,1U7VV@1239|Firmicutes,4IHT8@91061|Bacilli,3FA8J@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01093 1423732.BALS01000042_gene2674 1.62e-80 240.0 COG1302@1|root,COG1302@2|Bacteria,1VCNX@1239|Firmicutes,4HKR6@91061|Bacilli,3FB58@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function asp23 - - - - - - - - - - - Asp23 NAGPHGKN_01094 568703.LGG_00231 3.02e-87 257.0 COG1302@1|root,COG1302@2|Bacteria,1VJRA@1239|Firmicutes,4HXJN@91061|Bacilli,3F692@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function asp2 - - - - - - - - - - - Asp23 NAGPHGKN_01095 568703.LGG_00232 2.73e-166 463.0 COG1011@1|root,COG1011@2|Bacteria,1TQYM@1239|Firmicutes,4HPIM@91061|Bacilli,3F7UN@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 NAGPHGKN_01096 568703.LGG_00233 4.96e-148 418.0 COG3819@1|root,COG3819@2|Bacteria,1TT00@1239|Firmicutes,4HE38@91061|Bacilli,3F538@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF969) - - - - - - - - - - - - DUF969 NAGPHGKN_01097 1423816.BACQ01000030_gene1034 5.63e-186 520.0 COG3817@1|root,COG3817@2|Bacteria,1TQ17@1239|Firmicutes,4HAJT@91061|Bacilli,3F5QJ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF979) - - - - - - - - - - - - DUF979 NAGPHGKN_01098 568703.LGG_00238 5.7e-153 429.0 COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,4HCIJ@91061|Bacilli,3F46I@33958|Lactobacillaceae 91061|Bacilli O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 NAGPHGKN_01099 568703.LGG_00239 1.89e-133 379.0 COG2085@1|root,COG2085@2|Bacteria,1VW6H@1239|Firmicutes,4HWI6@91061|Bacilli,3F6QU@33958|Lactobacillaceae 91061|Bacilli S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored NAGPHGKN_01101 568703.LGG_00240 3.57e-165 461.0 COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,4HD1P@91061|Bacilli,3F4CH@33958|Lactobacillaceae 91061|Bacilli S glutamine amidotransferase cobQ - - ko:K07009 - - - - ko00000 - - - GATase_3 NAGPHGKN_01102 568703.LGG_00241 2.32e-86 254.0 29PCH@1|root,30AAR@2|Bacteria,1U6EK@1239|Firmicutes,4IG6D@91061|Bacilli,3F7R0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01103 568703.LGG_00242 9.03e-173 482.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,3F3ZX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB NAGPHGKN_01104 568703.LGG_00243 5.2e-188 523.0 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,3F4RU@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc NAGPHGKN_01105 568703.LGG_00244 3.67e-178 496.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,3F4AE@33958|Lactobacillaceae 91061|Bacilli D Sporulation initiation inhibitor soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 NAGPHGKN_01106 568703.LGG_00245 6.39e-201 557.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,3F47R@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc NAGPHGKN_01107 568703.LGG_00246 8.4e-42 136.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli,3F823@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF951) yyzM - - - - - - - - - - - DUF951 NAGPHGKN_01108 568703.LGG_00247 4.65e-256 703.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,3F3TK@33958|Lactobacillaceae 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C NAGPHGKN_01109 568703.LGG_00248 2.39e-182 508.0 COG4858@1|root,COG4858@2|Bacteria,1VF5N@1239|Firmicutes,4HH7B@91061|Bacilli,3F4JS@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1129) - - - - - - - - - - - - DUF1129 NAGPHGKN_01110 568703.LGG_00249 0.0 931.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,3F3XN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH NAGPHGKN_01111 568703.LGG_00251 1.67e-152 429.0 2F4SR@1|root,33XFD@2|Bacteria,1VW0F@1239|Firmicutes,4HWCG@91061|Bacilli,3F6TR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01112 568703.LGG_00252 1.68e-156 439.0 COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,3F3Y0@33958|Lactobacillaceae 91061|Bacilli K response regulator vanR - - - - - - - - - - - Response_reg,Trans_reg_C NAGPHGKN_01113 568703.LGG_00253 1.45e-280 767.0 COG5002@1|root,COG5002@2|Bacteria,1TPB6@1239|Firmicutes,4HARU@91061|Bacilli,3F479@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase hpk31 - - - - - - - - - - - HATPase_c,HisKA NAGPHGKN_01114 568703.LGG_00254 5.54e-303 827.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,3F43S@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 NAGPHGKN_01115 568703.LGG_00256 2.55e-111 320.0 COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,4HW8H@91061|Bacilli,3F6ZK@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N NAGPHGKN_01116 568703.LGG_00257 0.0 1014.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,3F3UE@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 - R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M NAGPHGKN_01117 568703.LGG_00258 1.83e-180 502.0 COG1794@1|root,COG1794@2|Bacteria,1V34N@1239|Firmicutes,4HG8W@91061|Bacilli,3F3XZ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the aspartate glutamate racemases family racD - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race NAGPHGKN_01118 568703.LGG_00259 1.93e-209 578.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,3F3PW@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase yvgN - - - - - - - - - - - Aldo_ket_red NAGPHGKN_01119 568703.LGG_00260 1.13e-181 506.0 COG1349@1|root,COG1349@2|Bacteria,1TTGR@1239|Firmicutes,4HEVD@91061|Bacilli,3F9D7@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain iolR - - ko:K06608,ko:K11534 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR NAGPHGKN_01120 568703.LGG_00261 0.0 924.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,3F3ZS@33958|Lactobacillaceae 91061|Bacilli EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family iolT GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K06609 - - - - ko00000,ko02000 2.A.1.1.26 - - Sugar_tr NAGPHGKN_01121 568703.LGG_00262 0.0 971.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family iolA GO:0003674,GO:0003824,GO:0004491,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh NAGPHGKN_01122 568703.LGG_00263 1.64e-198 549.0 COG3718@1|root,COG3718@2|Bacteria,1TR6M@1239|Firmicutes,4HCDY@91061|Bacilli,3F4TI@33958|Lactobacillaceae 91061|Bacilli G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) iolB - 5.3.1.30 ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08503 RC00541 ko00000,ko00001,ko01000 - - - KduI NAGPHGKN_01123 568703.LGG_00264 6.58e-227 625.0 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,4HB78@91061|Bacilli,3FC23@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) iolC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044424,GO:0044464,GO:0046434,GO:0046835,GO:0071704,GO:1901575 2.7.1.92 ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R05661 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU39740 PfkB NAGPHGKN_01124 568703.LGG_00265 0.0 1224.0 COG3962@1|root,COG3962@2|Bacteria,1UI18@1239|Firmicutes,4HCPP@91061|Bacilli,3F9EH@33958|Lactobacillaceae 91061|Bacilli E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) iolD GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0071704,GO:1901575 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08603 RC02331 ko00000,ko00001,ko01000 - - iYO844.BSU39730 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N NAGPHGKN_01125 568703.LGG_00266 1.12e-245 675.0 COG0673@1|root,COG0673@2|Bacteria,1TRHA@1239|Firmicutes,4HA6R@91061|Bacilli,3F4K5@33958|Lactobacillaceae 91061|Bacilli C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively iolG - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C NAGPHGKN_01126 568703.LGG_00267 1.01e-250 688.0 COG0673@1|root,COG0673@2|Bacteria,1TQJX@1239|Firmicutes,4HAJ8@91061|Bacilli,3F5FQ@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain iolG2 - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C NAGPHGKN_01127 568703.LGG_00268 2.99e-222 612.0 COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,4HCIM@91061|Bacilli,3F5FP@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) iolE - 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 - - - AP_endonuc_2 NAGPHGKN_01128 568703.LGG_00269 5.48e-202 560.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,3F9NW@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II iolJ - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39670 F_bP_aldolase NAGPHGKN_01129 568703.LGG_00270 1.75e-87 257.0 COG1942@1|root,COG1942@2|Bacteria,1V3SS@1239|Firmicutes,4HI9G@91061|Bacilli,3F6UD@33958|Lactobacillaceae 91061|Bacilli S Tautomerase enzyme yodA - - - - - - - - - - - Tautomerase_2 NAGPHGKN_01130 568703.LGG_00271 1.2e-203 564.0 COG4130@1|root,COG4130@2|Bacteria,1U626@1239|Firmicutes,4IFR6@91061|Bacilli,3F6UX@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase-like TIM barrel - - 5.3.99.11 ko:K06606 ko00562,ko01120,map00562,map01120 - R09952 RC01513 ko00000,ko00001,ko01000 - - - AP_endonuc_2 NAGPHGKN_01131 568703.LGG_00272 2.1e-215 593.0 COG1082@1|root,COG1082@2|Bacteria,1UZXE@1239|Firmicutes,4HEG4@91061|Bacilli,3F5PE@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase-like TIM barrel iolH - - ko:K06605 - - - - ko00000 - - - AP_endonuc_2 NAGPHGKN_01132 568703.LGG_00273 5.62e-190 528.0 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,3F42G@33958|Lactobacillaceae 91061|Bacilli K rpiR family gntR - - - - - - - - - - - HTH_6,SIS NAGPHGKN_01133 568703.LGG_00274 2.44e-82 250.0 COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,3F4X7@33958|Lactobacillaceae 91061|Bacilli G Dehydrogenase gntZ - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 NAGPHGKN_01134 568703.LGG_00274 1.1e-51 170.0 COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,3F4X7@33958|Lactobacillaceae 91061|Bacilli G Dehydrogenase gntZ - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 NAGPHGKN_01135 568703.LGG_00274 2.94e-54 177.0 COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,3F4X7@33958|Lactobacillaceae 91061|Bacilli G Dehydrogenase gntZ - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 NAGPHGKN_01136 568703.LGG_00275 0.0 1044.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,3F4R2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N NAGPHGKN_01137 568703.LGG_00277 4.61e-270 745.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,3F3V0@33958|Lactobacillaceae 91061|Bacilli EG Gluconate gntP - - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease NAGPHGKN_01138 568703.LGG_00284 3.08e-74 222.0 2CICD@1|root,3462T@2|Bacteria,1VZWZ@1239|Firmicutes,4HY4B@91061|Bacilli,3F6T8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01139 568703.LGG_00285 8.68e-169 471.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,3F49M@33958|Lactobacillaceae 91061|Bacilli P ABC transporter adcC - - ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 M00242,M00244,M00319 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU02860 ABC_tran NAGPHGKN_01140 568703.LGG_00286 2.96e-173 485.0 COG1108@1|root,COG1108@2|Bacteria,1V0SX@1239|Firmicutes,4HE09@91061|Bacilli,3F4BC@33958|Lactobacillaceae 91061|Bacilli U ABC 3 transport family znuB - - ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 NAGPHGKN_01141 568703.LGG_00287 6.52e-215 592.0 COG0639@1|root,COG0639@2|Bacteria,1UZK9@1239|Firmicutes,4HG1F@91061|Bacilli,3F5JR@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase superfamily domain prpA3 - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - Metallophos_2 NAGPHGKN_01142 568703.LGG_00288 3.89e-205 568.0 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,3F3XC@33958|Lactobacillaceae 91061|Bacilli I Dehydrogenase glxR - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 NAGPHGKN_01143 568703.LGG_00289 0.0 1183.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,3F4E5@33958|Lactobacillaceae 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N NAGPHGKN_01144 568703.LGG_00290 6.87e-256 702.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr NAGPHGKN_01145 568703.LGG_00292 2.15e-314 858.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans NAGPHGKN_01146 568703.LGG_00293 4.98e-98 291.0 COG3103@1|root,COG3103@2|Bacteria,1VB6H@1239|Firmicutes,4I1GZ@91061|Bacilli,3F66H@33958|Lactobacillaceae 91061|Bacilli T Sh3 type 3 domain protein - - - - - - - - - - - - LysM,SLAP NAGPHGKN_01147 568703.LGG_00294 2.29e-175 489.0 COG1349@1|root,COG1349@2|Bacteria,1V1VH@1239|Firmicutes,4HHQ0@91061|Bacilli,3FC5T@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain glcR - - ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR NAGPHGKN_01148 568703.LGG_00295 5.69e-189 524.0 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,4HVF8@91061|Bacilli,3FBRX@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 NAGPHGKN_01149 568703.LGG_00296 6.35e-172 480.0 COG5523@1|root,COG5523@2|Bacteria,1U7F2@1239|Firmicutes,4IHB0@91061|Bacilli,3F9IA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF975) - - - - - - - - - - - - DUF975 NAGPHGKN_01150 568703.LGG_00297 4.9e-69 209.0 29PTZ@1|root,30AS5@2|Bacteria,1U71D@1239|Firmicutes,4IGVU@91061|Bacilli,3F8UT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01151 568703.LGG_00298 4.32e-138 391.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HIQ4@91061|Bacilli,3F4SM@33958|Lactobacillaceae 91061|Bacilli U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 NAGPHGKN_01152 568703.LGG_00299 1.43e-97 290.0 COG1397@1|root,COG1397@2|Bacteria,1UZ60@1239|Firmicutes,4HF0W@91061|Bacilli,3F9P4@33958|Lactobacillaceae 91061|Bacilli O ADP-ribosylglycohydrolase - - 3.2.2.24 ko:K05521 - - - - ko00000,ko01000 - - - ADP_ribosyl_GH NAGPHGKN_01153 568703.LGG_00299 1.29e-88 268.0 COG1397@1|root,COG1397@2|Bacteria,1UZ60@1239|Firmicutes,4HF0W@91061|Bacilli,3F9P4@33958|Lactobacillaceae 91061|Bacilli O ADP-ribosylglycohydrolase - - 3.2.2.24 ko:K05521 - - - - ko00000,ko01000 - - - ADP_ribosyl_GH NAGPHGKN_01154 568703.LGG_00300 8.01e-209 587.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,3FC7X@33958|Lactobacillaceae 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn NAGPHGKN_01155 568703.LGG_00300 1.62e-131 385.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,3FC7X@33958|Lactobacillaceae 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn NAGPHGKN_01156 568703.LGG_00301 1.5e-178 497.0 COG0030@1|root,COG0030@2|Bacteria 2|Bacteria J rRNA (adenine-N6,N6-)-dimethyltransferase activity ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.197,2.5.1.134 ko:K02169,ko:K02528,ko:K17216,ko:K17462 ko00270,ko00780,ko01100,ko01230,map00270,map00780,map01100,map01230 M00572,M00609 R09543,R10305,R10404,R10716 RC00003,RC00020,RC00069,RC00460,RC03257 ko00000,ko00001,ko00002,ko01000,ko03009 - - - Methyltransf_11,Methyltransf_25,RrnaAD NAGPHGKN_01158 568703.LGG_00307 1.13e-93 273.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - NAGPHGKN_01159 568703.LGG_00302 1.45e-46 149.0 2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,4HRC7@91061|Bacilli,3F8E8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01160 568703.LGG_01899 0.0 973.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli,3FCE6@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family alsS - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N NAGPHGKN_01161 568703.LGG_01899 4.32e-23 97.1 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli,3FCE6@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family alsS - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N NAGPHGKN_01162 568703.LGG_01900 1.96e-126 360.0 29V6R@1|root,30GKF@2|Bacteria,1UG8K@1239|Firmicutes,4IF4K@91061|Bacilli,3F5MB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01163 568703.LGG_01901 1.69e-125 360.0 COG1670@1|root,COG1670@2|Bacteria,1V49W@1239|Firmicutes,4HHAP@91061|Bacilli,3F5A6@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain yjcK - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 NAGPHGKN_01164 568703.LGG_02097 9.6e-60 206.0 COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1TQ39@1239|Firmicutes,4HA3J@91061|Bacilli,3F5ED@33958|Lactobacillaceae 91061|Bacilli V Eco57I restriction-modification methylase - - - - - - - - - - - - Eco57I,N6_Mtase NAGPHGKN_01165 568703.LGG_02096 8.7e-257 704.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HA65@91061|Bacilli,3F3NJ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase NAGPHGKN_01166 568703.LGG_02097 1.49e-227 660.0 COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1TQ39@1239|Firmicutes,4HA3J@91061|Bacilli,3F5ED@33958|Lactobacillaceae 91061|Bacilli V Eco57I restriction-modification methylase - - - - - - - - - - - - Eco57I,N6_Mtase NAGPHGKN_01167 568703.LGG_02305 2.18e-169 479.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F431@33958|Lactobacillaceae 91061|Bacilli L Putative transposase DNA-binding domain tnpB - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon NAGPHGKN_01187 1423816.BACQ01000062_gene2320 2.96e-57 179.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F7I4@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin NAGPHGKN_01188 568703.LGG_00311 1.14e-169 475.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,3F4XE@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE NAGPHGKN_01189 568703.LGG_00312 2.94e-46 151.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,3F63I@33958|Lactobacillaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 NAGPHGKN_01190 568703.LGG_00312 1.49e-36 126.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,3F63I@33958|Lactobacillaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 NAGPHGKN_01191 568703.LGG_00313 2.32e-90 276.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,3F591@33958|Lactobacillaceae 91061|Bacilli E Receptor family ligand binding region livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 NAGPHGKN_01192 568703.LGG_00313 2.65e-145 417.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,3F591@33958|Lactobacillaceae 91061|Bacilli E Receptor family ligand binding region livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 NAGPHGKN_01193 568703.LGG_00314 5.16e-192 535.0 COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,3F56V@33958|Lactobacillaceae 91061|Bacilli U Branched-chain amino acid transport system / permease component livH - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 NAGPHGKN_01194 568703.LGG_00315 8.13e-185 518.0 COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,3F44M@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid transport system / permease component livM - - ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 NAGPHGKN_01195 568703.LGG_00316 7.09e-179 499.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,3F4IH@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid ATP-binding cassette transporter livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C NAGPHGKN_01196 568703.LGG_00317 6.48e-157 441.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,3F3RP@33958|Lactobacillaceae 91061|Bacilli E ABC transporter livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran NAGPHGKN_01197 568703.LGG_00318 6.94e-70 211.0 COG1694@1|root,COG1694@2|Bacteria,1V6C5@1239|Firmicutes,4HM7F@91061|Bacilli,3F7EC@33958|Lactobacillaceae 91061|Bacilli S MazG nucleotide pyrophosphohydrolase domain - - - - - - - - - - - - MazG NAGPHGKN_01198 568703.LGG_00319 8.54e-88 264.0 COG4814@1|root,COG4814@2|Bacteria,1V8NG@1239|Firmicutes,4HJ22@91061|Bacilli,3F41V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 NAGPHGKN_01199 568703.LGG_00319 1.26e-104 308.0 COG4814@1|root,COG4814@2|Bacteria,1V8NG@1239|Firmicutes,4HJ22@91061|Bacilli,3F41V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 NAGPHGKN_01200 568703.LGG_00320 1.12e-303 829.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HE28@91061|Bacilli,3FC6Y@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts14C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC NAGPHGKN_01201 568703.LGG_00321 2.32e-147 418.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,3F4M3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC,NUDIX NAGPHGKN_01202 568703.LGG_00322 3.78e-292 796.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,3F3Y4@33958|Lactobacillaceae 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme NAGPHGKN_01203 568703.LGG_00323 3.14e-166 465.0 COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli,3F4K1@33958|Lactobacillaceae 91061|Bacilli F Purine nucleoside phosphorylase deoD - 2.4.2.1 ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 NAGPHGKN_01204 568703.LGG_00324 4.22e-216 612.0 COG0791@1|root,COG0791@2|Bacteria,1VG0Z@1239|Firmicutes,4HBE9@91061|Bacilli,3F50V@33958|Lactobacillaceae 91061|Bacilli M NlpC P60 family protein p75 - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60,SLAP NAGPHGKN_01205 568703.LGG_00325 0.0 897.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase nox - 1.6.3.4 ko:K17869 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim NAGPHGKN_01206 1423732.BALS01000028_gene2282 0.0 919.0 COG1440@1|root,COG1455@1|root,COG1440@2|Bacteria,COG1455@2|Bacteria,1TQPV@1239|Firmicutes,4HC9I@91061|Bacilli,3F4DV@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase system, EIIC lacE - 2.7.1.207 ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00281 R04393 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1 - - PTS_EIIC,PTS_IIB NAGPHGKN_01207 1423732.BALS01000028_gene2283 5.96e-185 516.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,3F4SJ@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain - - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD NAGPHGKN_01208 1423732.BALS01000028_gene2284 3.11e-75 225.0 COG1447@1|root,COG1447@2|Bacteria,1VHIU@1239|Firmicutes,4HNX4@91061|Bacilli,3FCDJ@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit lacF-1 - 2.7.1.207 ko:K02786 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00281 R04393 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1 - - PTS_IIA NAGPHGKN_01209 936140.AEOT01000010_gene576 4.73e-294 808.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,3FC7B@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family lacG GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.21,3.2.1.85 ko:K01220,ko:K05350 ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03256,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 NAGPHGKN_01210 568703.LGG_00326 1.1e-197 548.0 28MN3@1|root,2ZAXQ@2|Bacteria,1US2T@1239|Firmicutes,4HW4H@91061|Bacilli,3F55K@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01211 568703.LGG_00327 1.81e-150 424.0 2EEPZ@1|root,338HP@2|Bacteria,1VJZJ@1239|Firmicutes,4HR6K@91061|Bacilli,3F55G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01212 568703.LGG_00328 0.0 1551.0 COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,3F473@33958|Lactobacillaceae 91061|Bacilli KL DEAD_2 uvrB3 - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1 NAGPHGKN_01213 568703.LGG_00329 1.31e-302 826.0 COG1653@1|root,COG1653@2|Bacteria,1TSBD@1239|Firmicutes,4IQ65@91061|Bacilli,3F5HX@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 NAGPHGKN_01214 568703.LGG_00330 1.74e-111 325.0 29V33@1|root,30GGE@2|Bacteria,1UFZH@1239|Firmicutes,4IF1H@91061|Bacilli,3F5BQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01215 1423816.BACQ01000062_gene2342 0.0 1020.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HB6A@91061|Bacilli,3F558@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 manR - - ko:K02538,ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB NAGPHGKN_01216 1423732.BALS01000028_gene2297 1.34e-88 261.0 COG1762@1|root,COG1762@2|Bacteria,1VFGA@1239|Firmicutes,4IFXP@91061|Bacilli,3F78D@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.202 ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 NAGPHGKN_01217 1423816.BACQ01000062_gene2344 1.31e-305 838.0 COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F5JV@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system manP - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIC,PTS_IIB NAGPHGKN_01218 568703.LGG_00331 1.19e-240 661.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,3F40I@33958|Lactobacillaceae 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI NAGPHGKN_01219 568703.LGG_00332 5.43e-167 467.0 COG2188@1|root,COG2188@2|Bacteria,1UYYY@1239|Firmicutes,4HGI6@91061|Bacilli,3F5F4@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA NAGPHGKN_01220 568703.LGG_00333 1.15e-280 767.0 COG2222@1|root,COG2222@2|Bacteria,1TQUT@1239|Firmicutes,4HDKQ@91061|Bacilli,3F3YS@33958|Lactobacillaceae 91061|Bacilli G SIS domain agaS - - ko:K02082 - - - - ko00000,ko01000 - - - SIS NAGPHGKN_01221 568703.LGG_00334 5.31e-287 783.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,3F40F@33958|Lactobacillaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 NAGPHGKN_01222 568703.LGG_00336 0.0 1233.0 COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,4HBAR@91061|Bacilli,3F5XU@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 35 bgaC - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - BetaGal_dom4_5,Glyco_hydro_35 NAGPHGKN_01223 568703.LGG_00337 3.25e-107 309.0 COG3444@1|root,COG3444@2|Bacteria,1V46G@1239|Firmicutes,4HHPN@91061|Bacilli,3FC7S@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb NAGPHGKN_01224 543734.LCABL_02930 2.07e-179 504.0 COG3715@1|root,COG3715@2|Bacteria,1TSX0@1239|Firmicutes,4HBRB@91061|Bacilli,3F4X4@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor NAGPHGKN_01225 568703.LGG_00339 3.66e-187 521.0 COG3716@1|root,COG3716@2|Bacteria,1UMKU@1239|Firmicutes,4HC75@91061|Bacilli,3F434@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA NAGPHGKN_01226 568703.LGG_00340 1.11e-84 249.0 COG2893@1|root,COG2893@2|Bacteria,1VB8U@1239|Firmicutes,4HKV5@91061|Bacilli,3F7YU@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man NAGPHGKN_01227 568703.LGG_00348 0.0 1016.0 COG0438@1|root,COG0438@2|Bacteria,1UY71@1239|Firmicutes,4HFBM@91061|Bacilli,3FC1Q@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Glycos_transf_1 NAGPHGKN_01228 568703.LGG_00349 0.0 1080.0 COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli,3F4P6@33958|Lactobacillaceae 91061|Bacilli M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon tagE GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Asp1,Glyco_trans_A_1,Glycos_transf_1 NAGPHGKN_01229 568703.LGG_00350 1.33e-292 800.0 2E865@1|root,332JJ@2|Bacteria,1VJ1K@1239|Firmicutes,4IFBU@91061|Bacilli,3F662@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2325) - - - - - - - - - - - - DUF2325 NAGPHGKN_01230 568703.LGG_00351 3.79e-293 799.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 NAGPHGKN_01231 568703.LGG_00352 2.08e-202 563.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HV4S@91061|Bacilli,3F9GC@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 NAGPHGKN_01232 568703.LGG_00352 7.48e-35 127.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HV4S@91061|Bacilli,3F9GC@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 NAGPHGKN_01233 568703.LGG_00353 0.0 869.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HEGS@91061|Bacilli,3FC71@33958|Lactobacillaceae 91061|Bacilli U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane - - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC NAGPHGKN_01234 568703.LGG_00354 2.02e-78 233.0 COG1440@1|root,COG1440@2|Bacteria,1V6UA@1239|Firmicutes,4HK0J@91061|Bacilli,3F8G8@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB NAGPHGKN_01235 568703.LGG_00355 3.76e-64 196.0 COG1447@1|root,COG1447@2|Bacteria,1VCDD@1239|Firmicutes,4HZCJ@91061|Bacilli,3F7P9@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit - - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA NAGPHGKN_01236 568703.LGG_00356 1.41e-247 681.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,3F55I@33958|Lactobacillaceae 91061|Bacilli E M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 NAGPHGKN_01237 568703.LGG_00357 0.0 1137.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TS2U@1239|Firmicutes,4HTK5@91061|Bacilli,3F6RZ@33958|Lactobacillaceae 91061|Bacilli GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,PRD,PTS_EIIA_2 NAGPHGKN_01238 568703.LGG_00358 1.3e-298 814.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,3F45V@33958|Lactobacillaceae 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 NAGPHGKN_01239 568703.LGG_00359 0.0 1030.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 NAGPHGKN_01240 568703.LGG_00360 3.71e-153 430.0 COG3153@1|root,COG3153@2|Bacteria,1V3PW@1239|Firmicutes,4HGZK@91061|Bacilli,3F7G3@33958|Lactobacillaceae 91061|Bacilli S Acetyltransferase (GNAT) family - - - ko:K03824 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_9 NAGPHGKN_01242 568703.LGG_00362 0.0 958.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli,3F53S@33958|Lactobacillaceae 91061|Bacilli V ABC transporter nisT - - ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko02000 3.A.1.106,3.A.1.109,3.A.1.111.2,3.A.1.111.3,3.A.1.21 - - ABC_membrane,ABC_tran NAGPHGKN_01243 543734.LCABL_03340 4.39e-34 126.0 29QQ0@1|root,30BPR@2|Bacteria,1U8FC@1239|Firmicutes,4IID8@91061|Bacilli,3FAX8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01244 543734.LCABL_03340 3.19e-49 165.0 29QQ0@1|root,30BPR@2|Bacteria,1U8FC@1239|Firmicutes,4IID8@91061|Bacilli,3FAX8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01245 568703.LGG_00363 4.57e-123 352.0 COG4721@1|root,COG4721@2|Bacteria,1V2G5@1239|Firmicutes,4IRFG@91061|Bacilli,3FBNZ@33958|Lactobacillaceae 91061|Bacilli S ABC-type cobalt transport system, permease component - - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt NAGPHGKN_01246 568703.LGG_00364 1.33e-311 850.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,3FBS0@33958|Lactobacillaceae 91061|Bacilli P ABC transporter - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran NAGPHGKN_01247 568703.LGG_00365 1.55e-141 400.0 COG0619@1|root,COG0619@2|Bacteria,1TUDZ@1239|Firmicutes,4HCPC@91061|Bacilli,3F4FG@33958|Lactobacillaceae 91061|Bacilli P cobalt transport ykoC - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ NAGPHGKN_01248 568703.LGG_00366 5.44e-163 456.0 COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,4HCPF@91061|Bacilli,3FB7U@33958|Lactobacillaceae 91061|Bacilli K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway tenA - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 NAGPHGKN_01249 568703.LGG_00367 1.46e-106 308.0 COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,4HHG6@91061|Bacilli,3F6M6@33958|Lactobacillaceae 91061|Bacilli S Thiamine-precursor transporter protein (ThiW) thiW - - - - - - - - - - - ThiW NAGPHGKN_01250 568703.LGG_00368 6.35e-100 295.0 COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,4HFTJ@91061|Bacilli,3F43J@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM - 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK NAGPHGKN_01251 568703.LGG_00368 7.84e-74 227.0 COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,4HFTJ@91061|Bacilli,3F43J@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM - 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK NAGPHGKN_01252 568703.LGG_00369 5.6e-132 376.0 COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,3FB7Y@33958|Lactobacillaceae 91061|Bacilli H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI NAGPHGKN_01253 568703.LGG_00370 4.28e-191 531.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,3F3NA@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin NAGPHGKN_01254 568703.LGG_00371 0.0 939.0 COG0531@1|root,COG0531@2|Bacteria,1UYSD@1239|Firmicutes,4IPMN@91061|Bacilli,3F48U@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 NAGPHGKN_01255 568703.LGG_00372 1.16e-239 659.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4HE07@91061|Bacilli,3F44Q@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding proteins and sugar binding domain of LacI family rbsR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 NAGPHGKN_01256 543734.LCABL_03220 2.78e-80 239.0 COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,4HIFW@91061|Bacilli,3F6GA@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose rbsD - 5.4.99.62 ko:K06726 ko02010,map02010 - R08247 RC02247 ko00000,ko00001,ko01000 - - - RbsD_FucU NAGPHGKN_01257 1423816.BACQ01000062_gene2383 0.0 928.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,3FBUB@33958|Lactobacillaceae 91061|Bacilli G ABC transporter rbsA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran NAGPHGKN_01258 1423816.BACQ01000062_gene2384 2.36e-205 571.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,3F5NF@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family rbsC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 NAGPHGKN_01259 543734.LCABL_03250 3.24e-204 568.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,4HCSN@91061|Bacilli,3FCEY@33958|Lactobacillaceae 91061|Bacilli G Periplasmic binding protein domain rbsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 NAGPHGKN_01260 568703.LGG_00373 2.71e-209 580.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HE6Z@91061|Bacilli,3FB6B@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB NAGPHGKN_01261 568703.LGG_00374 3.31e-58 181.0 COG3620@1|root,COG3620@2|Bacteria,1VAWH@1239|Firmicutes 1239|Firmicutes K DNA-binding helix-turn-helix protein - - - - - - - - - - - - HTH_3 NAGPHGKN_01262 568703.LGG_00375 7.37e-48 159.0 29QQ0@1|root,30BPR@2|Bacteria,1U8FC@1239|Firmicutes,4IID8@91061|Bacilli,3FAX8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01267 568703.LGG_00380 8.27e-183 509.0 299D6@1|root,2ZWG2@2|Bacteria,1V564@1239|Firmicutes,4HI66@91061|Bacilli,3F6SE@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 NAGPHGKN_01268 568703.LGG_00382 0.0 1257.0 COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,4IQSR@91061|Bacilli,3F5K3@33958|Lactobacillaceae 91061|Bacilli M NTF2-like N-terminal transpeptidase domain pbpC - - ko:K21467 - - - - ko00000,ko01011 - - - MecA_N,PBP_dimer,Transpeptidase NAGPHGKN_01269 543734.LCABL_03360 3.66e-67 209.0 29P6Z@1|root,30A52@2|Bacteria,1U67I@1239|Firmicutes,4IFY3@91061|Bacilli,3F796@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01270 1423732.BALS01000032_gene234 9.81e-111 322.0 COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,4I2PJ@91061|Bacilli,3F4H6@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_01271 543734.LCABL_03400 1.54e-103 306.0 29P41@1|root,30A28@2|Bacteria,1U63C@1239|Firmicutes,4IFSS@91061|Bacilli,3F6Y1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01272 543734.LCABL_03410 7.7e-79 243.0 29QRY@1|root,30BRT@2|Bacteria,1U8J4@1239|Firmicutes,4IIH3@91061|Bacilli,3FB1I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01273 543734.LCABL_03420 5.52e-121 352.0 2AIFZ@1|root,33KBF@2|Bacteria,1UPZ6@1239|Firmicutes,4IVDJ@91061|Bacilli,3F6BW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01274 568703.LGG_00386 4.33e-98 298.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F4D4@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1,MFS_3 NAGPHGKN_01275 568703.LGG_00386 6.17e-177 503.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F4D4@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1,MFS_3 NAGPHGKN_01276 568703.LGG_00387 2.77e-89 263.0 COG1846@1|root,COG1846@2|Bacteria,1V939@1239|Firmicutes,4HJRC@91061|Bacilli,3F7MR@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR NAGPHGKN_01277 568703.LGG_00388 7.11e-135 381.0 2DEN3@1|root,32U3P@2|Bacteria,1VXXQ@1239|Firmicutes,4HXNG@91061|Bacilli,3F73U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01278 568703.LGG_00389 4.94e-40 132.0 2ATAB@1|root,31ITC@2|Bacteria,1U735@1239|Firmicutes,4IGXP@91061|Bacilli,3F8WX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01279 543734.LCABL_03450 8.81e-204 584.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4H9N4@91061|Bacilli,3F64K@33958|Lactobacillaceae 91061|Bacilli GKT transcriptional antiterminator - - - - - - - - - - - - HTH_11,Mga,PRD,PTS_EIIA_2 NAGPHGKN_01280 543734.LCABL_03470 1.27e-61 189.0 COG3414@1|root,COG3414@2|Bacteria,1VBHM@1239|Firmicutes,4HM7H@91061|Bacilli,3F96C@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB NAGPHGKN_01281 543734.LCABL_03480 4.22e-287 786.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HBAD@91061|Bacilli,3F4Y4@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component - - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT NAGPHGKN_01282 543734.LCABL_03490 1.75e-54 173.0 2DQQD@1|root,32UPI@2|Bacteria,1VIC6@1239|Firmicutes,4HSMN@91061|Bacilli,3F8E7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - TPR_1 NAGPHGKN_01283 543734.LCABL_03500 6.56e-192 534.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HA99@91061|Bacilli,3F611@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase NAGPHGKN_01284 543734.LCABL_03510 1.1e-112 327.0 COG0645@1|root,COG0645@2|Bacteria,1V4KB@1239|Firmicutes,4HI0A@91061|Bacilli,3F7CA@33958|Lactobacillaceae 91061|Bacilli S Zeta toxin - - - - - - - - - - - - AAA_33,Zeta_toxin NAGPHGKN_01285 543734.LCABL_03800 7.6e-199 553.0 COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,4HB17@91061|Bacilli,3F4T0@33958|Lactobacillaceae 91061|Bacilli F Nucleoside rihC - 3.2.2.1 ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro NAGPHGKN_01286 543734.LCABL_03810 3.22e-164 471.0 COG3069@1|root,COG3069@2|Bacteria,1U0AJ@1239|Firmicutes,4HB8W@91061|Bacilli,3F9NU@33958|Lactobacillaceae 91061|Bacilli C Tripartite ATP-independent periplasmic transporter, DctM component dcuC - - ko:K03326 - - - - ko00000,ko02000 2.A.61.1 - - DcuC NAGPHGKN_01287 543734.LCABL_03810 2.21e-92 283.0 COG3069@1|root,COG3069@2|Bacteria,1U0AJ@1239|Firmicutes,4HB8W@91061|Bacilli,3F9NU@33958|Lactobacillaceae 91061|Bacilli C Tripartite ATP-independent periplasmic transporter, DctM component dcuC - - ko:K03326 - - - - ko00000,ko02000 2.A.61.1 - - DcuC NAGPHGKN_01289 543734.LCABL_03830 5.49e-44 149.0 COG2188@1|root,COG2188@2|Bacteria,1V4G6@1239|Firmicutes,4HG0G@91061|Bacilli,3F8G0@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - GntR NAGPHGKN_01290 543734.LCABL_03830 6.4e-92 274.0 COG2188@1|root,COG2188@2|Bacteria,1V4G6@1239|Firmicutes,4HG0G@91061|Bacilli,3F8G0@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - GntR NAGPHGKN_01291 1545702.LACWKB8_0318 6.49e-111 327.0 COG1830@1|root,COG1830@2|Bacteria,1TR4S@1239|Firmicutes,4HWA1@91061|Bacilli,3F9XH@33958|Lactobacillaceae 91061|Bacilli G DeoC/LacD family aldolase - - - - - - - - - - - - DeoC NAGPHGKN_01292 1545702.LACWKB8_0317 8.81e-49 163.0 COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,4I614@91061|Bacilli,3FAPB@33958|Lactobacillaceae 91061|Bacilli K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA - - - ko:K02443 - - - - ko00000,ko03000 - - - G3P_antiterm NAGPHGKN_01293 1545702.LACWKB8_0316 4.02e-223 632.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,3F4R2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the FGGY kinase family xylB - 2.7.1.17,2.7.1.53 ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 M00014 R01639,R01901,R07127 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N NAGPHGKN_01294 1545702.LACWKB8_0315 1.96e-117 343.0 COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,3F4IC@33958|Lactobacillaceae 91061|Bacilli IQ KR domain fabG10 - 1.1.1.100,1.3.1.28 ko:K00059,ko:K00216 ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212 M00083,M00572 R01505,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117,RC00534 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 NAGPHGKN_01295 1545702.LACWKB8_0314 7.36e-159 454.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4HAA7@91061|Bacilli,3FBTK@33958|Lactobacillaceae 91061|Bacilli EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C NAGPHGKN_01296 218140.BPSY_0744 1.77e-198 561.0 COG3775@1|root,COG3775@2|Bacteria,2IBG5@201174|Actinobacteria,4D0NN@85004|Bifidobacteriales 201174|Actinobacteria G PTS system sugar-specific permease component - - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT NAGPHGKN_01297 543734.LCABL_04050 0.0 988.0 COG3711@1|root,COG3711@2|Bacteria,1TQTV@1239|Firmicutes,4HFDM@91061|Bacilli 91061|Bacilli K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - - - - - - - - - - HTH_11,PRD,PTS_EIIA_2 NAGPHGKN_01298 543734.LCABL_04060 2.62e-198 550.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HD42@91061|Bacilli,3F58Z@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase NAGPHGKN_01299 543734.LCABL_04070 0.0 1157.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F9FH@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system - - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB NAGPHGKN_01300 543734.LCABL_04220 8.47e-304 827.0 COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,4HBV4@91061|Bacilli,3F602@33958|Lactobacillaceae 91061|Bacilli E Alcohol dehydrogenase GroES-like domain - - - ko:K19956 ko00051,map00051 - R03234 RC00089 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N NAGPHGKN_01301 543734.LCABL_04230 2.81e-209 580.0 COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4HCAR@91061|Bacilli,3F4PP@33958|Lactobacillaceae 91061|Bacilli K sugar-binding domain protein - - - - - - - - - - - - Sugar-bind NAGPHGKN_01302 543734.LCABL_04240 2.81e-167 470.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli,3F4CR@33958|Lactobacillaceae 91061|Bacilli IQ NAD dependent epimerase/dehydratase family srlD2 - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short NAGPHGKN_01303 543734.LCABL_04250 2.14e-81 242.0 COG2893@1|root,COG2893@2|Bacteria,1VGQT@1239|Firmicutes,4HNXM@91061|Bacilli,3F7YA@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.206 ko:K02812 ko00051,ko02060,map00051,map02060 M00278 R04076 RC01069,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.3 - - EIIA-man NAGPHGKN_01304 543734.LCABL_04260 1.65e-102 298.0 COG3444@1|root,COG3444@2|Bacteria,1V3X7@1239|Firmicutes,4HH17@91061|Bacilli,3F6T0@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.206 ko:K02813 ko00051,ko02060,map00051,map02060 M00278 R04076 RC01069,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.3 - - PTSIIB_sorb NAGPHGKN_01305 543734.LCABL_04270 1.64e-176 494.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli,3F5QK@33958|Lactobacillaceae 91061|Bacilli U PTS system sorbose-specific iic component - - - ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277,M00278 R02630,R04076,R08366 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.3,4.A.6.1.4 - - EII-Sor NAGPHGKN_01306 543734.LCABL_04280 5.62e-191 531.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component manZ - - ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00278 R02630,R04076 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.3 - - EIID-AGA NAGPHGKN_01307 543734.LCABL_04290 1.12e-189 529.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HGMN@91061|Bacilli,3FCBA@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II kbaY - 4.1.2.13,4.1.2.40 ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01069,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase NAGPHGKN_01308 543734.LCABL_04300 7.42e-303 832.0 COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,4H9UV@91061|Bacilli 91061|Bacilli P transporter sdcS GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0034220,GO:0044425,GO:0051179,GO:0051234,GO:0055085,GO:0098656 - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp NAGPHGKN_01309 543734.LCABL_04310 3.7e-217 609.0 COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,4HBWH@91061|Bacilli 91061|Bacilli C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_oxidored NAGPHGKN_01310 543734.LCABL_04320 3.95e-138 399.0 COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HFSV@91061|Bacilli,3F48I@33958|Lactobacillaceae 1239|Firmicutes K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate NAGPHGKN_01311 568703.LGG_00428 2.63e-203 562.0 COG1912@1|root,COG1912@2|Bacteria,1TSR3@1239|Firmicutes,4HAW6@91061|Bacilli,3F3JD@33958|Lactobacillaceae 91061|Bacilli K S-adenosyl-l-methionine hydroxide adenosyltransferase XK27_10120 - - - - - - - - - - - SAM_adeno_trans NAGPHGKN_01312 568703.LGG_00429 1.43e-125 358.0 COG4720@1|root,COG4720@2|Bacteria,1V1GT@1239|Firmicutes,4HGAE@91061|Bacilli,3F5A7@33958|Lactobacillaceae 91061|Bacilli S UPF0397 protein - - - ko:K16924 - M00582 - - ko00000,ko00002,ko02000 3.A.1.29 - - ECF-ribofla_trS NAGPHGKN_01313 568703.LGG_00430 0.0 1095.0 COG1123@1|root,COG4172@2|Bacteria,1VRD0@1239|Firmicutes,4ISFN@91061|Bacilli,3FBXM@33958|Lactobacillaceae 91061|Bacilli P ATP-binding cassette cobalt transporter - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 NAGPHGKN_01314 568703.LGG_00431 1.02e-188 525.0 COG0619@1|root,COG0619@2|Bacteria,1TPMV@1239|Firmicutes,4HBTW@91061|Bacilli,3F3Y9@33958|Lactobacillaceae 91061|Bacilli P cobalt transport cbiQ - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iSB619.SA_RS14165 CbiQ NAGPHGKN_01315 1423816.BACQ01000063_gene2423 6.08e-192 538.0 COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,4HBNT@91061|Bacilli,3F5CG@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LacI family cytR - - ko:K02529,ko:K03604 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 NAGPHGKN_01316 1423816.BACQ01000063_gene2424 1.69e-311 851.0 COG2211@1|root,COG2211@2|Bacteria,1TRP7@1239|Firmicutes,4HCUK@91061|Bacilli,3F3YZ@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 NAGPHGKN_01317 1423816.BACQ01000063_gene2425 3.54e-57 192.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459 NAGPHGKN_01318 1423816.BACQ01000063_gene2425 1.81e-295 813.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459 NAGPHGKN_01319 543734.LCABL_03440 0.0 889.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4ISAE@91061|Bacilli,3FBRV@33958|Lactobacillaceae 91061|Bacilli C HI0933-like protein frdC - 1.3.5.1,1.3.5.4 ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C NAGPHGKN_01320 1158609.I586_02712 1.88e-123 358.0 COG0235@1|root,COG0235@2|Bacteria,1V57Z@1239|Firmicutes,4HGYY@91061|Bacilli,4B0P5@81852|Enterococcaceae 91061|Bacilli G Class II Aldolase and Adducin N-terminal domain - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II NAGPHGKN_01322 1123300.AUIN01000011_gene1405 2.02e-236 660.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HAIT@91061|Bacilli 91061|Bacilli G iic component pts36C - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT NAGPHGKN_01323 1122998.AUHZ01000006_gene730 1.47e-08 55.5 COG3414@1|root,COG3414@2|Bacteria,2GQN9@201174|Actinobacteria 201174|Actinobacteria G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_IIB NAGPHGKN_01324 1121864.OMO_01653 4.95e-39 136.0 COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes,4HPPC@91061|Bacilli,4B2BT@81852|Enterococcaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 pts36A - 2.7.1.200 ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_EIIA_2 NAGPHGKN_01325 568703.LGG_00408 1.62e-81 251.0 COG1349@1|root,COG1349@2|Bacteria,1V097@1239|Firmicutes,4HGA7@91061|Bacilli,3F5GM@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - ko:K02530 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR NAGPHGKN_01326 873449.STRCR_1098 2.12e-65 216.0 COG1105@1|root,COG1105@2|Bacteria,1TR9H@1239|Firmicutes,4HAGR@91061|Bacilli 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily - - 2.7.1.144 ko:K00917 ko00052,ko01100,map00052,map01100 - R03236 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB NAGPHGKN_01327 1114972.AUAW01000012_gene1174 2.26e-72 230.0 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,3F42G@33958|Lactobacillaceae 91061|Bacilli K rpiR family gntR - - - - - - - - - - - HTH_6,SIS NAGPHGKN_01328 1111121.HMPREF1247_0397 8e-41 140.0 COG1762@1|root,COG1762@2|Bacteria,2I8CH@201174|Actinobacteria 201174|Actinobacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 ulaC - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_EIIA_2,PTS_IIB NAGPHGKN_01329 1114972.AUAW01000012_gene1176 3.85e-230 643.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HBAD@91061|Bacilli,3F4Y4@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component - - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT NAGPHGKN_01330 77635.BISU_0530 4.79e-35 122.0 COG3414@1|root,COG3414@2|Bacteria 2|Bacteria G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity - - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB NAGPHGKN_01331 77635.BISU_0529 2.24e-159 457.0 COG2220@1|root,COG2220@2|Bacteria 2|Bacteria S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - - - - - - - - - - Lactamase_B_2 NAGPHGKN_01332 1231336.L248_2980 2.45e-21 90.9 COG0561@1|root,COG0561@2|Bacteria,1TR2E@1239|Firmicutes,4HCEA@91061|Bacilli,3F4G9@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 NAGPHGKN_01333 1462526.BN990_02988 1.17e-20 93.6 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,4C4PE@84406|Virgibacillus 91061|Bacilli S haloacid dehalogenase-like hydrolase yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 NAGPHGKN_01334 936140.AEOT01000002_gene2138 4.21e-277 763.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9TM@91061|Bacilli,3F4W5@33958|Lactobacillaceae 91061|Bacilli G Family 4 glycosyl hydrolase C-terminal domain malH - 3.2.1.122 ko:K01232 ko00500,map00500 - R00837,R00838,R06113 RC00049 ko00000,ko00001,ko01000 - GH4 - Glyco_hydro_4,Glyco_hydro_4C NAGPHGKN_01335 936140.AEOT01000002_gene2139 1.25e-263 743.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,3F44V@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system, EIIB glvC - 2.7.1.208 ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 M00268 R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8 - - PTS_EIIB,PTS_EIIC NAGPHGKN_01336 525365.HMPREF0548_0644 8.14e-48 167.0 COG1737@1|root,COG1737@2|Bacteria,1V2J8@1239|Firmicutes,4IQVX@91061|Bacilli,3FBJH@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family glvR - - ko:K03481 - - - - ko00000,ko03000 - - - HTH_6,SIS NAGPHGKN_01338 1139996.OMQ_00159 1.91e-11 70.1 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,4AZCR@81852|Enterococcaceae 91061|Bacilli G phosphotransferase system, EIIB glvC - 2.7.1.208 ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 M00268 R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8 - - PTS_EIIB,PTS_EIIC NAGPHGKN_01339 1293597.BN147_01560 1.01e-56 182.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,3FC0X@33958|Lactobacillaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ptbA - 2.7.1.208 ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1 NAGPHGKN_01340 1139219.I569_02191 3.75e-65 208.0 COG0637@1|root,COG0637@2|Bacteria,1V75J@1239|Firmicutes,4HFK1@91061|Bacilli,4B1ZA@81852|Enterococcaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 NAGPHGKN_01341 1234679.BN424_136 1.74e-116 343.0 COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,4HBB3@91061|Bacilli 91061|Bacilli K antiterminator - - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD NAGPHGKN_01342 1234679.BN424_135 3.04e-293 818.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system bglP11 - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NAGPHGKN_01343 1234679.BN424_134 6.59e-291 801.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,27FFY@186828|Carnobacteriaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 NAGPHGKN_01344 543734.LCABL_03910 8.13e-294 808.0 COG3711@1|root,COG3711@2|Bacteria,1TSGM@1239|Firmicutes,4HB3W@91061|Bacilli,3F482@33958|Lactobacillaceae 91061|Bacilli K PRD domain - - - ko:K02538 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB NAGPHGKN_01345 543734.LCABL_03920 4.54e-40 139.0 COG1762@1|root,COG1762@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system ptsN GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 - - PTS_EIIA_2 NAGPHGKN_01346 543734.LCABL_03930 2.17e-215 595.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HD42@91061|Bacilli,3F58Z@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase NAGPHGKN_01347 543734.LCABL_03940 9.91e-87 257.0 COG1762@1|root,COG1762@2|Bacteria,1V5TG@1239|Firmicutes,4HND7@91061|Bacilli,3F7H8@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.202 ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 NAGPHGKN_01348 543734.LCABL_03950 4.75e-58 181.0 COG1445@1|root,COG1445@2|Bacteria,1VASC@1239|Firmicutes,4HKYF@91061|Bacilli,3F7K8@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.202 ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_IIB NAGPHGKN_01349 543734.LCABL_03960 9.7e-211 588.0 COG1299@1|root,COG1299@2|Bacteria,1TPKU@1239|Firmicutes,4H9XS@91061|Bacilli,3F52Q@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase System - - - ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.2.1 - - PTS_EIIC NAGPHGKN_01350 543734.LCABL_03970 1.7e-60 196.0 COG2017@1|root,COG2017@2|Bacteria,1V5SP@1239|Firmicutes,4IRIW@91061|Bacilli,3F96V@33958|Lactobacillaceae 91061|Bacilli G Domain of unknown function (DUF4432) - - - - - - - - - - - - DUF4432 NAGPHGKN_01351 543734.LCABL_03970 4.13e-80 248.0 COG2017@1|root,COG2017@2|Bacteria,1V5SP@1239|Firmicutes,4IRIW@91061|Bacilli,3F96V@33958|Lactobacillaceae 91061|Bacilli G Domain of unknown function (DUF4432) - - - - - - - - - - - - DUF4432 NAGPHGKN_01352 543734.LCABL_03980 5.1e-144 408.0 COG3822@1|root,COG3822@2|Bacteria,1UXBF@1239|Firmicutes,4HVN6@91061|Bacilli,3F9JP@33958|Lactobacillaceae 91061|Bacilli S Pfam:DUF1498 - - 5.3.1.15 ko:K09988 ko00040,map00040 - R01898 RC00516 ko00000,ko00001,ko01000 - - - Lyx_isomer NAGPHGKN_01353 543734.LCABL_03990 2.92e-248 693.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,3F4R2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the FGGY kinase family xylB - 2.7.1.17,2.7.1.53 ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 M00014 R01639,R01901,R07127 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N NAGPHGKN_01354 1231377.C426_1280 4.05e-258 722.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli 91061|Bacilli G pts system - - 2.7.1.208 ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 M00268 R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NAGPHGKN_01355 1231377.C426_1279 8.16e-108 318.0 COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,4HGXQ@91061|Bacilli 91061|Bacilli G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides - - 3.5.1.105 ko:K03478 - - - - ko00000,ko01000 - - - YdjC NAGPHGKN_01356 1231377.C426_1278 4.41e-104 307.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9TM@91061|Bacilli 91061|Bacilli G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases - - 3.2.1.122,3.2.1.86 ko:K01222,ko:K01232 ko00010,ko00500,map00010,map00500 - R00837,R00838,R00839,R05133,R05134,R06113 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GH4,GT4 - Glyco_hydro_4,Glyco_hydro_4C NAGPHGKN_01357 1121871.AUAT01000047_gene1798 1.97e-91 283.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9TM@91061|Bacilli,27EBJ@186827|Aerococcaceae 91061|Bacilli G Family 4 glycosyl hydrolase - - 3.2.1.122,3.2.1.86 ko:K01222,ko:K01232 ko00010,ko00500,map00010,map00500 - R00837,R00838,R00839,R05133,R05134,R06113 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GH4,GT4 - Glyco_hydro_4,Glyco_hydro_4C NAGPHGKN_01358 1605.Lani381_0304 4.07e-24 104.0 COG1737@1|root,COG1737@2|Bacteria,1TR69@1239|Firmicutes,4HE3S@91061|Bacilli,3F46J@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - ko:K03481 - - - - ko00000,ko03000 - - - HTH_6,SIS NAGPHGKN_01359 543734.LCABL_04010 2.4e-80 240.0 COG1762@1|root,COG1762@2|Bacteria,1VDC4@1239|Firmicutes,4HNDE@91061|Bacilli,3FCBG@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - ko:K11201 - M00306 - - ko00000,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 NAGPHGKN_01360 543734.LCABL_04020 0.0 936.0 COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1TPKU@1239|Firmicutes,4HD9N@91061|Bacilli,3FCBF@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit pts31BC - - ko:K11202,ko:K11203 - M00306 - - ko00000,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIC,PTS_IIB NAGPHGKN_01361 543734.LCABL_04030 7.61e-240 664.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F5DH@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class I and II malY - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 NAGPHGKN_01362 543734.LCABL_04040 8.71e-271 757.0 2DX0A@1|root,342SP@2|Bacteria,1UIXQ@1239|Firmicutes,4ISW1@91061|Bacilli,3F9EI@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - - - - - - - - - - HTH_11,PTS_EIIA_2 NAGPHGKN_01363 1423775.BAMN01000013_gene765 8.9e-83 251.0 COG0794@1|root,COG0794@2|Bacteria,1TQ04@1239|Firmicutes,4HGZ0@91061|Bacilli,3F7HT@33958|Lactobacillaceae 91061|Bacilli M SIS domain kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS NAGPHGKN_01364 1423775.BAMN01000013_gene764 6.54e-58 184.0 COG1762@1|root,COG1762@2|Bacteria,1V42N@1239|Firmicutes,4HP6Y@91061|Bacilli 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_EIIA_2 NAGPHGKN_01365 1423775.BAMN01000013_gene763 3.78e-42 140.0 COG3414@1|root,COG3414@2|Bacteria,1VFJK@1239|Firmicutes,4HQ69@91061|Bacilli,3F8MG@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB NAGPHGKN_01366 1423775.BAMN01000013_gene762 2.88e-106 318.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HBAD@91061|Bacilli,3F4Y4@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component - - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT NAGPHGKN_01367 1423775.BAMN01000013_gene762 8.83e-96 291.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HBAD@91061|Bacilli,3F4Y4@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component - - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT NAGPHGKN_01368 1423775.BAMN01000013_gene761 1.67e-109 326.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4IQWR@91061|Bacilli,3FBJP@33958|Lactobacillaceae 91061|Bacilli E Dihydrodipicolinate synthetase family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS NAGPHGKN_01369 1423775.BAMN01000013_gene760 2.4e-92 276.0 COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,3F6AY@33958|Lactobacillaceae 91061|Bacilli G KDPG and KHG aldolase eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase NAGPHGKN_01370 1423775.BAMN01000013_gene759 8.41e-244 699.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4H9N4@91061|Bacilli,3F5NN@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB NAGPHGKN_01371 1235797.C816_01682 1.74e-15 73.6 COG1733@1|root,COG1733@2|Bacteria,1V6I9@1239|Firmicutes,24JYH@186801|Clostridia 186801|Clostridia K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR NAGPHGKN_01372 1302286.BAOT01000051_gene1831 1.84e-73 229.0 COG0778@1|root,COG0778@2|Bacteria,1V6AG@1239|Firmicutes,4HN5N@91061|Bacilli,3F6YM@33958|Lactobacillaceae 91061|Bacilli C nitroreductase - - - - - - - - - - - - Nitroreductase NAGPHGKN_01373 568703.LGG_00482 1.48e-163 459.0 29Q5Q@1|root,30B4M@2|Bacteria,1U7IV@1239|Firmicutes,4IHFN@91061|Bacilli,3F9S6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01375 568703.LGG_00485 4.39e-25 93.6 29QPW@1|root,30BPK@2|Bacteria,1U8F6@1239|Firmicutes,4IID2@91061|Bacilli,3FAX1@33958|Lactobacillaceae 91061|Bacilli S YvrJ protein family - - - - - - - - - - - - YvrJ NAGPHGKN_01376 568703.LGG_00486 1.98e-186 517.0 COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V3SH@1239|Firmicutes,4HNR1@91061|Bacilli,3F6ZF@33958|Lactobacillaceae 91061|Bacilli M hydrolase, family 25 - - - - - - - - - - - - Glyco_hydro_25,LysM,SH3_5 NAGPHGKN_01377 568703.LGG_00488 2.54e-112 323.0 COG1309@1|root,COG1309@2|Bacteria,1V4D3@1239|Firmicutes,4HJ8Z@91061|Bacilli,3F6ZM@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N NAGPHGKN_01378 568703.LGG_00489 1.56e-235 650.0 COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,3F3K5@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease yxeA - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD NAGPHGKN_01379 568703.LGG_00490 1.22e-154 435.0 COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli,3F4RP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_01380 568703.LGG_00491 0.0 902.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase npr - 1.11.1.1 ko:K05910 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim NAGPHGKN_01381 568703.LGG_00492 2.15e-193 536.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,3F55S@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - - - - - - - - - - - Hydrolase_3 NAGPHGKN_01382 568703.LGG_00493 8.23e-61 186.0 COG3041@1|root,COG3041@2|Bacteria,1U69Z@1239|Firmicutes,4IG17@91061|Bacilli,3F7EP@33958|Lactobacillaceae 91061|Bacilli S Bacterial toxin of type II toxin-antitoxin system, YafQ - - - ko:K19157 - - - - ko00000,ko01000,ko02048 - - - YafQ_toxin NAGPHGKN_01383 543734.LCABL_04720 1.8e-209 582.0 COG1609@1|root,COG1609@2|Bacteria,1TRHK@1239|Firmicutes,4HB9P@91061|Bacilli,3F5FI@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding proteins and sugar binding domain of LacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 NAGPHGKN_01384 543734.LCABL_04730 8.14e-98 286.0 COG3444@1|root,COG3444@2|Bacteria,1V8BP@1239|Firmicutes,4HWNX@91061|Bacilli,3F6R3@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb NAGPHGKN_01385 1423732.BALS01000052_gene2777 2.05e-165 466.0 COG3715@1|root,COG3715@2|Bacteria,1TSX0@1239|Firmicutes,4HBRB@91061|Bacilli,3F4X4@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor NAGPHGKN_01386 543734.LCABL_04750 3.49e-185 516.0 COG3716@1|root,COG3716@2|Bacteria,1TSXA@1239|Firmicutes,4IQM2@91061|Bacilli,3FBHP@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA NAGPHGKN_01387 543734.LCABL_04760 0.0 1221.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HB1D@91061|Bacilli,3F4CE@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 31 family - - - - - - - - - - - - Glyco_hydro_31 NAGPHGKN_01388 543734.LCABL_04770 5.03e-80 239.0 COG2893@1|root,COG2893@2|Bacteria,1V7TP@1239|Firmicutes,4IQPD@91061|Bacilli,3F76S@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man NAGPHGKN_01389 543734.LCABL_04780 0.0 1060.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C NAGPHGKN_01390 568703.LGG_00494 1.35e-174 488.0 COG1708@1|root,COG1708@2|Bacteria,1UCIC@1239|Firmicutes,4HEP7@91061|Bacilli,3F5YN@33958|Lactobacillaceae 91061|Bacilli H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin ant1 - 2.7.7.47 ko:K00984 - - - - ko00000,ko01000,ko01504 - - - DUF4111,NTP_transf_2 NAGPHGKN_01394 568703.LGG_00500 2.12e-192 535.0 COG1464@1|root,COG1464@2|Bacteria,1V0Z6@1239|Firmicutes,4HBBW@91061|Bacilli,3FC6K@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family metQ1 - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 NAGPHGKN_01395 568703.LGG_00501 9.29e-250 684.0 COG3049@1|root,COG3049@2|Bacteria,1UZCV@1239|Firmicutes,4HFHU@91061|Bacilli,3FB8Y@33958|Lactobacillaceae 91061|Bacilli M Linear amide C-N hydrolases, choloylglycine hydrolase family - - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH NAGPHGKN_01396 568703.LGG_00502 2.77e-222 613.0 29Q1F@1|root,30B00@2|Bacteria,1U7BS@1239|Firmicutes,4IH72@91061|Bacilli,3F9AV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01397 568703.LGG_00503 0.0 1140.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,4HAYH@91061|Bacilli,3F3QX@33958|Lactobacillaceae 91061|Bacilli S Myosin-crossreactive antigen l1n - 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA NAGPHGKN_01398 568703.LGG_00504 1.61e-24 91.7 29QJ1@1|root,30BIK@2|Bacteria,1U86E@1239|Firmicutes,4II3Y@91061|Bacilli,3FAKU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01399 568703.LGG_00505 1.18e-134 381.0 COG1309@1|root,COG1309@2|Bacteria,1VCF7@1239|Firmicutes,4IQ66@91061|Bacilli,3FBG6@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_8,TetR_N NAGPHGKN_01400 1423816.BACQ01000064_gene2472 1.22e-77 231.0 COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,4HKCN@91061|Bacilli,3F6YE@33958|Lactobacillaceae 91061|Bacilli S PTS system fructose IIA component dhaM GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05881 ko00561,map00561 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000,ko02000 - - - EIIA-man NAGPHGKN_01401 568703.LGG_00508 1.42e-133 379.0 COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,4HGZY@91061|Bacilli,3F5VS@33958|Lactobacillaceae 91061|Bacilli S Dak2 dhaL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak2 NAGPHGKN_01402 568703.LGG_00509 2e-240 661.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,4H9VS@91061|Bacilli,3F4F2@33958|Lactobacillaceae 91061|Bacilli G Dak1 domain dhaK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05878 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak1 NAGPHGKN_01403 568703.LGG_00510 1.75e-100 291.0 COG1764@1|root,COG1764@2|Bacteria,1VY9T@1239|Firmicutes,4HXI7@91061|Bacilli,3F7CX@33958|Lactobacillaceae 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC NAGPHGKN_01404 568703.LGG_00375 2.52e-16 78.6 29QQ0@1|root,30BPR@2|Bacteria,1U8FC@1239|Firmicutes,4IID8@91061|Bacilli,3FAX8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01408 568703.LGG_00518 0.0 877.0 29Q2U@1|root,30B1F@2|Bacteria,1U7DD@1239|Firmicutes,4IH99@91061|Bacilli,3F9F1@33958|Lactobacillaceae 91061|Bacilli L Exonuclease - - - - - - - - - - - - RNase_T NAGPHGKN_01409 1423732.BALS01000020_gene355 1.27e-37 128.0 COG3077@1|root,COG3077@2|Bacteria,1U800@1239|Firmicutes,4IHXE@91061|Bacilli,3FADD@33958|Lactobacillaceae 91061|Bacilli L RelB antitoxin - - - - - - - - - - - - RelB NAGPHGKN_01410 1423816.BACQ01000058_gene2216 1.52e-39 132.0 2AIE5@1|root,318VJ@2|Bacteria,1U80U@1239|Firmicutes,4IHY8@91061|Bacilli,3FAE7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01411 568703.LGG_00520 1.04e-64 197.0 COG0640@1|root,COG0640@2|Bacteria,1VAK2@1239|Firmicutes,4HMC7@91061|Bacilli,3F704@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain yczG - - - - - - - - - - - HTH_20,HTH_5 NAGPHGKN_01412 568703.LGG_00521 8.1e-262 719.0 COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,3F4X1@33958|Lactobacillaceae 91061|Bacilli EGP transporter yceJ - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1,Sugar_tr NAGPHGKN_01413 568703.LGG_00522 2.19e-136 385.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,3F5KA@33958|Lactobacillaceae 91061|Bacilli L glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco NAGPHGKN_01414 1235801.C822_01441 4.31e-97 288.0 COG2452@1|root,COG2452@2|Bacteria,1UZ1U@1239|Firmicutes,4HIH3@91061|Bacilli,3F5I9@33958|Lactobacillaceae 91061|Bacilli L Resolvase, N-terminal - - - - - - - - - - - - MerR,MerR_1,Resolvase NAGPHGKN_01415 568703.LGG_02305 8.67e-276 755.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F431@33958|Lactobacillaceae 91061|Bacilli L Putative transposase DNA-binding domain tnpB - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon NAGPHGKN_01417 568703.LGG_00523 4.01e-44 143.0 28UH9@1|root,2ZGN0@2|Bacteria,1W65H@1239|Firmicutes,4I0DI@91061|Bacilli,3F8A7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01418 568703.LGG_00524 7.61e-215 592.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,3F4EF@33958|Lactobacillaceae 91061|Bacilli G Fructose-1,6-bisphosphate aldolase, class II fba - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase NAGPHGKN_01419 568703.LGG_00525 0.0 1141.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family cidC - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - iSB619.SA_RS13340 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N NAGPHGKN_01420 568703.LGG_00526 5.86e-61 187.0 29PJA@1|root,30AHF@2|Bacteria,1U6P2@1239|Firmicutes,4IGG0@91061|Bacilli,3F88B@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01421 1423732.BALS01000020_gene350 1.69e-192 540.0 COG1680@1|root,COG1680@2|Bacteria,1UZUZ@1239|Firmicutes,4IPQ5@91061|Bacilli,3F969@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Beta-lactamase,DUF3471 NAGPHGKN_01422 568703.LGG_00530 2.26e-245 675.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,3F4XQ@33958|Lactobacillaceae 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family ykfB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N NAGPHGKN_01423 568703.LGG_00532 1.9e-20 87.4 COG2227@1|root,COG2227@2|Bacteria,1UIIR@1239|Firmicutes,4ISJH@91061|Bacilli,3F5MJ@33958|Lactobacillaceae 91061|Bacilli H Protein of unknown function (DUF1698) - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 NAGPHGKN_01424 568703.LGG_00532 4.21e-120 346.0 COG2227@1|root,COG2227@2|Bacteria,1UIIR@1239|Firmicutes,4ISJH@91061|Bacilli,3F5MJ@33958|Lactobacillaceae 91061|Bacilli H Protein of unknown function (DUF1698) - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 NAGPHGKN_01425 568703.LGG_00534 3.54e-180 502.0 COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,3F4PK@33958|Lactobacillaceae 91061|Bacilli S peptidase C26 puuD - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 NAGPHGKN_01426 1423816.BACQ01000055_gene2117 6.71e-135 390.0 COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,4HGAF@91061|Bacilli,3F4R3@33958|Lactobacillaceae 91061|Bacilli S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii NAGPHGKN_01427 1423732.BALS01000062_gene2205 2.96e-101 297.0 COG5340@1|root,COG5340@2|Bacteria,1U65Z@1239|Firmicutes,4IFW0@91061|Bacilli,3F75B@33958|Lactobacillaceae 91061|Bacilli K Psort location Cytoplasmic, score - - - - - - - - - - - - - NAGPHGKN_01428 568703.LGG_00536 0.0 889.0 COG0174@1|root,COG0174@2|Bacteria,1U0IB@1239|Firmicutes,4HTS7@91061|Bacilli,3F98A@33958|Lactobacillaceae 91061|Bacilli E Glutamine synthetase N-terminal domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N_2 NAGPHGKN_01429 568703.LGG_00538 5.06e-282 769.0 COG2159@1|root,COG2159@2|Bacteria,1V9T6@1239|Firmicutes,4HKS1@91061|Bacilli,3F96M@33958|Lactobacillaceae 91061|Bacilli S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 NAGPHGKN_01430 568703.LGG_00539 6.46e-290 794.0 COG0531@1|root,COG0531@2|Bacteria,1V01X@1239|Firmicutes,4HVQJ@91061|Bacilli,3F7SQ@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease,AA_permease_2 NAGPHGKN_01431 568703.LGG_00540 1.82e-97 283.0 COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4HH53@91061|Bacilli,3F7ID@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 NAGPHGKN_01432 568703.LGG_00541 1.52e-207 573.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HAG6@91061|Bacilli,3FB4S@33958|Lactobacillaceae 91061|Bacilli S reductase - - - - - - - - - - - - Aldo_ket_red NAGPHGKN_01433 568703.LGG_00542 4.95e-246 675.0 COG0604@1|root,COG0604@2|Bacteria,1TRNC@1239|Firmicutes,4HATC@91061|Bacilli,3F48F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily qor - 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 NAGPHGKN_01434 568703.LGG_00543 9.54e-78 231.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HH0A@91061|Bacilli,3F7S1@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, HxlR family ydeP - - - - - - - - - - - HxlR NAGPHGKN_01435 568703.LGG_00544 2.64e-164 461.0 COG0730@1|root,COG0730@2|Bacteria,1VR9G@1239|Firmicutes,4HV4W@91061|Bacilli,3F3TR@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE NAGPHGKN_01436 568703.LGG_00545 1e-251 693.0 29PHK@1|root,30AFR@2|Bacteria,1U6KS@1239|Firmicutes,4IGDI@91061|Bacilli,3F847@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01437 568703.LGG_00546 2.47e-166 466.0 COG1131@1|root,COG1131@2|Bacteria,1TRTC@1239|Firmicutes,4HG0J@91061|Bacilli,3F59T@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities XK27_12140 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_01438 568703.LGG_00547 0.0 1017.0 28IHZ@1|root,2Z8J5@2|Bacteria,1TQV6@1239|Firmicutes,4HPC9@91061|Bacilli,3F5NC@33958|Lactobacillaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - NAGPHGKN_01439 568703.LGG_00548 1.98e-163 457.0 COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,4HHWT@91061|Bacilli,3F536@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein, C terminal - - - ko:K20488 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C NAGPHGKN_01440 568703.LGG_00549 7.75e-258 708.0 COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,4HBC0@91061|Bacilli,3F4NF@33958|Lactobacillaceae 91061|Bacilli T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K20487 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA NAGPHGKN_01441 568703.LGG_00550 1.2e-197 549.0 COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,4HD67@91061|Bacilli,3F5Y2@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran NAGPHGKN_01442 568703.LGG_00551 1.81e-252 694.0 28IVE@1|root,2Z8TU@2|Bacteria,1UYXD@1239|Firmicutes,4HMX1@91061|Bacilli,3F500@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 NAGPHGKN_01443 568703.LGG_00552 8.65e-136 385.0 2CZFI@1|root,30A49@2|Bacteria,1U667@1239|Firmicutes,4IFWD@91061|Bacilli,3F761@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01444 568703.LGG_00554 0.0 1674.0 COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli,3F3UH@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 NAGPHGKN_01445 568703.LGG_00555 0.0 953.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HBIP@91061|Bacilli,3FCAH@33958|Lactobacillaceae 91061|Bacilli E amino acid ycaM - - - - - - - - - - - AA_permease_2 NAGPHGKN_01446 568703.LGG_00557 2.09e-302 827.0 COG2211@1|root,COG2211@2|Bacteria,1VRWM@1239|Firmicutes,4HTJK@91061|Bacilli,3FBC3@33958|Lactobacillaceae 91061|Bacilli G MFS/sugar transport protein xylP - - - - - - - - - - - MFS_2 NAGPHGKN_01447 568703.LGG_00558 4.03e-104 302.0 COG3477@1|root,COG3477@2|Bacteria,1VX0K@1239|Firmicutes,4HX2R@91061|Bacilli,3F6A5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1440) - - - ko:K08996 - - - - ko00000 - - - DUF1440 NAGPHGKN_01448 568703.LGG_00567 9.58e-209 575.0 COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli,3F5CA@33958|Lactobacillaceae 91061|Bacilli E Transfers an acetyl group from acetyl-CoA to metA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS NAGPHGKN_01449 568703.LGG_00568 1.27e-221 611.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,3F4VD@33958|Lactobacillaceae 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP NAGPHGKN_01451 568703.LGG_00569 2.58e-179 499.0 2DMZ9@1|root,32UJF@2|Bacteria,1V5SH@1239|Firmicutes,4HKAC@91061|Bacilli,3F68Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01453 568703.LGG_00571 1.94e-269 738.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,3F3Y2@33958|Lactobacillaceae 91061|Bacilli E cystathionine mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP NAGPHGKN_01454 568703.LGG_00572 1.61e-184 514.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,3F4MH@33958|Lactobacillaceae 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family tcyA - - ko:K02424 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 NAGPHGKN_01455 568703.LGG_00573 9.6e-156 438.0 COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,4H9N1@91061|Bacilli,3F4QR@33958|Lactobacillaceae 91061|Bacilli E ABC transporter tcyB - - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1 NAGPHGKN_01456 568703.LGG_00574 2.12e-173 488.0 29Q72@1|root,30B62@2|Bacteria,1U7KY@1239|Firmicutes,4IHI1@91061|Bacilli,3F9VZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01457 568703.LGG_00575 1.2e-308 843.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans NAGPHGKN_01458 543734.LCABL_06680 3.31e-98 291.0 2DDU7@1|root,2ZJAU@2|Bacteria,1UM02@1239|Firmicutes 1239|Firmicutes S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL NAGPHGKN_01459 568703.LGG_00577 1.18e-228 631.0 COG4072@1|root,COG4072@2|Bacteria,1VCXS@1239|Firmicutes,4HKJG@91061|Bacilli,3F5HA@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein - - - - - - - - - - - - DUF3324,DUF916 NAGPHGKN_01460 568703.LGG_00578 3.8e-61 189.0 2AIBJ@1|root,318SM@2|Bacteria,1U7ZW@1239|Firmicutes,4IHXA@91061|Bacilli,3FAD9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Gram_pos_anchor NAGPHGKN_01461 568703.LGG_00579 6.7e-304 851.0 COG4886@1|root,COG4886@2|Bacteria,1UVV2@1239|Firmicutes,4I2C5@91061|Bacilli,3F806@33958|Lactobacillaceae 91061|Bacilli S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - WxL NAGPHGKN_01463 568703.LGG_00583 3.52e-163 457.0 2DDU7@1|root,2ZJAU@2|Bacteria 2|Bacteria S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL NAGPHGKN_01464 568703.LGG_00584 2.63e-73 221.0 29QPU@1|root,30BPI@2|Bacteria,1U8F4@1239|Firmicutes,4IID0@91061|Bacilli,3FAWZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01465 568703.LGG_00585 6.79e-152 428.0 COG5492@1|root,COG5492@2|Bacteria,1W54S@1239|Firmicutes,4IF30@91061|Bacilli,3F5H0@33958|Lactobacillaceae 91061|Bacilli N WxL domain surface cell wall-binding - - - - - - - - - - - - WxL NAGPHGKN_01466 568703.LGG_00587 0.0 1357.0 COG4886@1|root,COG4886@2|Bacteria,1UVV3@1239|Firmicutes,4I2C6@91061|Bacilli,3F8E0@33958|Lactobacillaceae 91061|Bacilli S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - WxL NAGPHGKN_01467 568703.LGG_00588 1.21e-211 587.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family yicL - - - - - - - - - - - EamA NAGPHGKN_01468 568703.LGG_00590 0.0 1075.0 28HMX@1|root,2Z7WB@2|Bacteria,1TPJG@1239|Firmicutes,4HBRI@91061|Bacilli,3F6T9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01469 568703.LGG_00591 7.71e-185 514.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCT1@91061|Bacilli,3F5PG@33958|Lactobacillaceae 91061|Bacilli V ABC transporter CcmA5 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_01470 1423816.BACQ01000040_gene1616 2.58e-101 296.0 COG4720@1|root,COG4720@2|Bacteria,1V52B@1239|Firmicutes,4HJY9@91061|Bacilli,3FBCH@33958|Lactobacillaceae 91061|Bacilli S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS NAGPHGKN_01471 568703.LGG_00595 3.96e-187 521.0 COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli,3F3V7@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin NAGPHGKN_01472 568703.LGG_00596 5.32e-209 577.0 COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,4HGHI@91061|Bacilli,3FB7R@33958|Lactobacillaceae 91061|Bacilli C Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR NAGPHGKN_01473 568703.LGG_00597 0.0 1529.0 COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli,3F3VW@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 NAGPHGKN_01474 568703.LGG_00598 0.0 1079.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein XK27_09600 - - ko:K06147,ko:K18891 ko02010,map02010 M00708 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 - - ABC_membrane,ABC_tran NAGPHGKN_01475 568703.LGG_00599 0.0 1132.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147,ko:K18892 ko02010,map02010 M00708 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 - - ABC_membrane,ABC_tran NAGPHGKN_01476 568703.LGG_00600 2.07e-281 770.0 COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli,3F4XT@33958|Lactobacillaceae 91061|Bacilli P Major Facilitator Superfamily oxlT - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 NAGPHGKN_01477 568703.LGG_00601 3.66e-165 462.0 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli,3F62J@33958|Lactobacillaceae 91061|Bacilli K UTRA treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA NAGPHGKN_01478 568703.LGG_00602 0.0 1140.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C NAGPHGKN_01479 568703.LGG_00603 0.0 1271.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system treB - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NAGPHGKN_01480 568703.LGG_00604 4.39e-273 751.0 COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,4HBEC@91061|Bacilli,3FB7N@33958|Lactobacillaceae 91061|Bacilli U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) sstT - - ko:K07862 - - - - ko00000,ko02000 2.A.23.4 - - SDF NAGPHGKN_01481 568703.LGG_00605 0.0 934.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 NAGPHGKN_01482 568703.LGG_00606 3.78e-220 607.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F4MZ@33958|Lactobacillaceae 91061|Bacilli C lactate/malate dehydrogenase, alpha/beta C-terminal domain ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N NAGPHGKN_01483 568703.LGG_00607 2.98e-315 859.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,3F4DS@33958|Lactobacillaceae 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N NAGPHGKN_01484 1423732.BALS01000009_gene740 3.08e-43 140.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3F7RG@33958|Lactobacillaceae 91061|Bacilli K 'Cold-shock' DNA-binding domain cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD NAGPHGKN_01485 568703.LGG_00610 3.02e-92 270.0 29PCC@1|root,30AAK@2|Bacteria,1U6ED@1239|Firmicutes,4IG65@91061|Bacilli,3F7QE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01486 568703.LGG_00611 1.95e-99 288.0 COG1764@1|root,COG1764@2|Bacteria,1VBJ0@1239|Firmicutes,4HNBY@91061|Bacilli,3F664@33958|Lactobacillaceae 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC NAGPHGKN_01487 568703.LGG_00612 2.36e-230 641.0 COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,4HBFK@91061|Bacilli,3F53D@33958|Lactobacillaceae 91061|Bacilli S ABC transporter yjcA - - ko:K19350 ko02010,map02010 - - - ko00000,ko00001,ko01504,ko02000 3.A.1.121 - - ABC_tran,ABC_tran_Xtn NAGPHGKN_01488 568703.LGG_00612 4.74e-109 326.0 COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,4HBFK@91061|Bacilli,3F53D@33958|Lactobacillaceae 91061|Bacilli S ABC transporter yjcA - - ko:K19350 ko02010,map02010 - - - ko00000,ko00001,ko01504,ko02000 3.A.1.121 - - ABC_tran,ABC_tran_Xtn NAGPHGKN_01489 568703.LGG_00614 1.11e-146 413.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,3F521@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding ylbE - - - - - - - - - - - NAD_binding_10 NAGPHGKN_01490 568703.LGG_00615 1.02e-203 564.0 COG0656@1|root,COG0656@2|Bacteria,1VSK5@1239|Firmicutes,4HT3F@91061|Bacilli,3FBX5@33958|Lactobacillaceae 91061|Bacilli S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red NAGPHGKN_01491 568703.LGG_00616 0.0 886.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yifK - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease NAGPHGKN_01492 568703.LGG_00617 0.0 1230.0 29PJG@1|root,30AHM@2|Bacteria,1U6PG@1239|Firmicutes,4IGGF@91061|Bacilli,3F896@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3800) - - - - - - - - - - - - DUF3800 NAGPHGKN_01493 568703.LGG_00618 0.0 1231.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter nhaK - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger NAGPHGKN_01494 568703.LGG_00619 7.8e-78 233.0 2C5CN@1|root,2ZGHZ@2|Bacteria,1W5A8@1239|Firmicutes,4I240@91061|Bacilli,3F89I@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 NAGPHGKN_01495 568703.LGG_00620 1.51e-89 264.0 COG3279@1|root,COG3279@2|Bacteria,1W04J@1239|Firmicutes,4HRMI@91061|Bacilli,3F6TA@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR NAGPHGKN_01496 568703.LGG_00621 5.16e-190 529.0 COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,4HJK7@91061|Bacilli,3FCET@33958|Lactobacillaceae 91061|Bacilli V ABC-2 type transporter - - - ko:K11051 ko02010,map02010 M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1.130 - - ABC2_membrane,ABC2_membrane_3 NAGPHGKN_01497 568703.LGG_00622 7.73e-201 557.0 COG1131@1|root,COG1131@2|Bacteria,1TPJE@1239|Firmicutes,4HB5U@91061|Bacilli,3F58G@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01990,ko:K11050 ko02010,map02010 M00254,M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.130 - - ABC_tran NAGPHGKN_01498 568703.LGG_00623 5.46e-187 519.0 COG4814@1|root,COG4814@2|Bacteria,1VXHZ@1239|Firmicutes,4HX59@91061|Bacilli,3F75V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 NAGPHGKN_01499 568703.LGG_00624 3.41e-144 407.0 COG3338@1|root,COG3338@2|Bacteria,1V16J@1239|Firmicutes,4HA62@91061|Bacilli,3F7DZ@33958|Lactobacillaceae 91061|Bacilli P Eukaryotic-type carbonic anhydrase cah - 4.2.1.1 ko:K01674 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Carb_anhydrase NAGPHGKN_01500 568703.LGG_00625 1.06e-69 210.0 COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,4HKGZ@91061|Bacilli,3F6YC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0145 family ybjQ - - - - - - - - - - - YbjQ_1 NAGPHGKN_01501 568703.LGG_00627 1.72e-120 343.0 COG2816@1|root,COG2816@2|Bacteria,1V6WC@1239|Firmicutes,4I1JJ@91061|Bacilli,3FBGF@33958|Lactobacillaceae 91061|Bacilli L NUDIX domain - - 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX NAGPHGKN_01502 568703.LGG_00632 1.23e-200 557.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,3F3WU@33958|Lactobacillaceae 91061|Bacilli C nadph quinone reductase - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 NAGPHGKN_01503 568703.LGG_00633 1.09e-310 847.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,3F3X1@33958|Lactobacillaceae 91061|Bacilli P ammonium transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp NAGPHGKN_01504 568703.LGG_00634 1.62e-226 624.0 COG2837@1|root,COG2837@2|Bacteria,1UY9Y@1239|Firmicutes,4HACQ@91061|Bacilli,3F45Z@33958|Lactobacillaceae 91061|Bacilli P Peroxidase ywbN GO:0005575,GO:0005576 - ko:K07223,ko:K16301 - - - - ko00000,ko01000,ko02000 2.A.108.2.3 - iYO844.BSU38260 Dyp_perox,TAT_signal NAGPHGKN_01505 568703.LGG_00635 3.15e-153 431.0 COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,4HHDI@91061|Bacilli,3FB83@33958|Lactobacillaceae 91061|Bacilli S MgtC family yqgG - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC NAGPHGKN_01506 568703.LGG_00636 2.15e-195 541.0 COG2169@1|root,COG2169@2|Bacteria,1V4X2@1239|Firmicutes,4HIF5@91061|Bacilli,3F3Y8@33958|Lactobacillaceae 91061|Bacilli F DNA RNA non-specific endonuclease endA - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2,Endonuclease_NS NAGPHGKN_01508 568703.LGG_00638 2.29e-196 555.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,3F3ZJ@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn NAGPHGKN_01509 568703.LGG_00638 1.1e-174 499.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,3F3ZJ@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn NAGPHGKN_01510 1423816.BACQ01000077_gene2617 0.0 946.0 COG0249@1|root,COG0249@2|Bacteria,1TPJP@1239|Firmicutes,4HD9G@91061|Bacilli,3F5Q9@33958|Lactobacillaceae 91061|Bacilli L ATPase domain of DNA mismatch repair MUTS family - - - - - - - - - - - - MutS_V NAGPHGKN_01511 568703.LGG_00641 8.94e-146 409.0 COG1573@1|root,COG1573@2|Bacteria,1V1F8@1239|Firmicutes,4HFVS@91061|Bacilli,3F4WH@33958|Lactobacillaceae 91061|Bacilli L Uracil-DNA glycosylase ung2 - - - - - - - - - - - UDG NAGPHGKN_01512 568703.LGG_00642 8.08e-172 479.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,3F4J6@33958|Lactobacillaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP NAGPHGKN_01513 568703.LGG_00643 0.0 1195.0 COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,3F5BS@33958|Lactobacillaceae 91061|Bacilli C C-terminal domain of alpha-glycerophosphate oxidase glpD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 - R00846,R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C NAGPHGKN_01514 568703.LGG_00644 0.0 1011.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,3F3WI@33958|Lactobacillaceae 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N NAGPHGKN_01515 568703.LGG_00645 1.76e-174 486.0 COG0463@1|root,COG0463@2|Bacteria,1V95V@1239|Firmicutes,4HJ1J@91061|Bacilli,3FC1Y@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 epsG - - - - - - - - - - - Glycos_transf_2 NAGPHGKN_01516 568703.LGG_00648 5.46e-178 498.0 COG3711@1|root,COG3711@2|Bacteria,1VS0S@1239|Firmicutes,4HTFM@91061|Bacilli,3F6AX@33958|Lactobacillaceae 91061|Bacilli K PRD domain lacT - - ko:K02531 - - - - ko00000,ko03000 - - - CAT_RBD,PRD NAGPHGKN_01517 568703.LGG_00649 0.0 1092.0 COG1440@1|root,COG1455@1|root,COG1440@2|Bacteria,COG1455@2|Bacteria,1TQPV@1239|Firmicutes,4HC9I@91061|Bacilli,3F4DV@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase system, EIIC lacE GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016310,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704 2.7.1.207 ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00281 R04393 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1 - - PTS_EIIC,PTS_IIB NAGPHGKN_01518 543734.LCABL_07280 4.65e-312 853.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,3FC7B@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family lacG GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.21,3.2.1.85,3.2.1.86 ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03256,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 NAGPHGKN_01519 568703.LGG_00652 8.62e-66 201.0 COG1447@1|root,COG1447@2|Bacteria,1V87W@1239|Firmicutes,4HJSY@91061|Bacilli,3FCDI@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit lacF - 2.7.1.196,2.7.1.205,2.7.1.207 ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 - - PTS_IIA NAGPHGKN_01521 568703.LGG_00653 2.83e-283 773.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli,3F3Q9@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg NAGPHGKN_01522 1423732.BALS01000009_gene700 1.64e-32 120.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,3F3YF@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd NAGPHGKN_01523 568703.LGG_00654 1.93e-203 564.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,3F3YF@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd NAGPHGKN_01524 568703.LGG_00655 0.0 980.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli,3F4D8@33958|Lactobacillaceae 91061|Bacilli G UDP-glucose--hexose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf NAGPHGKN_01525 568703.LGG_00656 5.88e-213 591.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,3F3PB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator msmR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 NAGPHGKN_01526 568703.LGG_00657 5.59e-250 685.0 COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,4HADZ@91061|Bacilli,3F48R@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of alpha and beta anomers of maltose galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim NAGPHGKN_01528 543734.LCABL_07380 4.46e-91 269.0 COG1762@1|root,COG1762@2|Bacteria,1VBW9@1239|Firmicutes,4IR84@91061|Bacilli,3FBMU@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.204 ko:K20112 ko02060,map02060 M00807 R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5 - - PTS_EIIA_2 NAGPHGKN_01529 1423816.BACQ01000077_gene2635 2.13e-64 196.0 COG3414@1|root,COG3414@2|Bacteria,1VACD@1239|Firmicutes,4HKHR@91061|Bacilli,3F732@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.204 ko:K20113 ko02060,map02060 M00807 R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5 - - PTS_IIB NAGPHGKN_01530 543734.LCABL_07400 0.0 889.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HBJG@91061|Bacilli,3FCCG@33958|Lactobacillaceae 91061|Bacilli G PTS system sugar-specific permease component gatC - - ko:K20114 ko02060,map02060 M00807 R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5 - - EIIC-GAT NAGPHGKN_01532 568703.LGG_00661 1.91e-38 128.0 29QNH@1|root,30BN4@2|Bacteria,1U8CP@1239|Firmicutes,4IIAN@91061|Bacilli,3FAUA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01533 568703.LGG_00662 8.15e-241 662.0 COG1680@1|root,COG1680@2|Bacteria,1U7F7@1239|Firmicutes,4IHB6@91061|Bacilli,3F9IK@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase NAGPHGKN_01534 568703.LGG_00663 3.84e-161 451.0 28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,4HMHN@91061|Bacilli,3F6AW@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4867) - - - - - - - - - - - - DUF4867 NAGPHGKN_01535 568703.LGG_00664 1.43e-224 619.0 COG1105@1|root,COG1105@2|Bacteria,1TR9H@1239|Firmicutes,4HAGR@91061|Bacilli,3F56E@33958|Lactobacillaceae 91061|Bacilli H pfkB family carbohydrate kinase lacC - 2.7.1.144 ko:K00917 ko00052,ko01100,map00052,map01100 - R03236 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB NAGPHGKN_01536 568703.LGG_00665 1.2e-238 656.0 COG3684@1|root,COG3684@2|Bacteria,1TQRR@1239|Firmicutes,4HBS9@91061|Bacilli,3F3UA@33958|Lactobacillaceae 91061|Bacilli G Belongs to the aldolase LacD family lacD - 4.1.2.40 ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 - R01069 RC00438,RC00439 ko00000,ko00001,ko01000 - - - DeoC NAGPHGKN_01537 568703.LGG_00666 1.85e-121 346.0 COG0698@1|root,COG0698@2|Bacteria,1U9Y4@1239|Firmicutes,4HE4C@91061|Bacilli,3F41M@33958|Lactobacillaceae 91061|Bacilli G Ribose/Galactose Isomerase lacB - 5.3.1.26 ko:K01819 ko00052,ko01100,map00052,map01100 - R03240 RC00376 ko00000,ko00001,ko01000 - - - LacAB_rpiB NAGPHGKN_01538 568703.LGG_00667 6.59e-96 279.0 COG0698@1|root,COG0698@2|Bacteria,1V5VZ@1239|Firmicutes,4HJK6@91061|Bacilli,3F6CQ@33958|Lactobacillaceae 91061|Bacilli G Ribose/Galactose Isomerase lacA - 5.3.1.26 ko:K01819 ko00052,ko01100,map00052,map01100 - R03240 RC00376 ko00000,ko00001,ko01000 - - - LacAB_rpiB NAGPHGKN_01539 568703.LGG_00668 1.01e-181 506.0 COG1349@1|root,COG1349@2|Bacteria,1V097@1239|Firmicutes,4HGA7@91061|Bacilli,3F5GM@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - ko:K02530 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR NAGPHGKN_01540 568703.LGG_00669 2.46e-120 345.0 COG0546@1|root,COG0546@2|Bacteria,1V7U6@1239|Firmicutes,4HJ9I@91061|Bacilli,3F658@33958|Lactobacillaceae 91061|Bacilli S HAD hydrolase, family IA, variant - - - - - - - - - - - - HAD_2 NAGPHGKN_01541 1423732.BALS01000026_gene2343 2.4e-15 72.4 COG0546@1|root,COG0546@2|Bacteria,1V7U6@1239|Firmicutes,4HJ9I@91061|Bacilli,3F658@33958|Lactobacillaceae 91061|Bacilli S HAD hydrolase, family IA, variant - - - - - - - - - - - - HAD_2 NAGPHGKN_01542 568703.LGG_00670 4.96e-270 739.0 COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli,3F4A9@33958|Lactobacillaceae 91061|Bacilli L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C NAGPHGKN_01543 568703.LGG_00671 0.0 1620.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,3F3TE@33958|Lactobacillaceae 91061|Bacilli L Putative exonuclease SbcCD, C subunit sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C NAGPHGKN_01544 1423732.BALS01000026_gene2347 4.79e-21 83.2 29PWB@1|root,30AUN@2|Bacteria,1U74I@1239|Firmicutes,4IGZ5@91061|Bacilli,3F8YT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01545 568703.LGG_00675 5.22e-112 321.0 COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HPDH@91061|Bacilli,3F7DR@33958|Lactobacillaceae 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family hsp1 - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 NAGPHGKN_01546 568703.LGG_00676 9.26e-129 375.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,3FCD0@33958|Lactobacillaceae 91061|Bacilli L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 NAGPHGKN_01547 568703.LGG_00676 1.71e-123 359.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,3FCD0@33958|Lactobacillaceae 91061|Bacilli L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 NAGPHGKN_01548 568703.LGG_00677 5.27e-191 530.0 COG0657@1|root,COG0657@2|Bacteria,1VEC5@1239|Firmicutes,4HKY6@91061|Bacilli,3F50A@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 NAGPHGKN_01549 568703.LGG_00678 1.22e-155 437.0 COG2249@1|root,COG2249@2|Bacteria,1V4UF@1239|Firmicutes,4HIR3@91061|Bacilli,3F6XY@33958|Lactobacillaceae 91061|Bacilli S Flavodoxin-like fold yrkL - - - - - - - - - - - Flavodoxin_2 NAGPHGKN_01551 568703.LGG_00680 1.34e-115 332.0 COG3247@1|root,COG3247@2|Bacteria,1VK2X@1239|Firmicutes,4HQFY@91061|Bacilli,3F7G9@33958|Lactobacillaceae 91061|Bacilli S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 NAGPHGKN_01552 568703.LGG_00681 3.18e-195 541.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,3F3NA@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin NAGPHGKN_01553 568703.LGG_00682 8.01e-254 696.0 29Q0Q@1|root,30AZ6@2|Bacteria,1U7AN@1239|Firmicutes,4IH5M@91061|Bacilli,3F980@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01555 568703.LGG_00684 2.6e-150 423.0 COG2910@1|root,COG2910@2|Bacteria,1U7HS@1239|Firmicutes,4IHEE@91061|Bacilli,3F9QF@33958|Lactobacillaceae 91061|Bacilli S NmrA-like family - - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 NAGPHGKN_01556 568703.LGG_00685 0.0 1556.0 COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,3F43A@33958|Lactobacillaceae 91061|Bacilli G hydrolase, family 3 bglB - 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C NAGPHGKN_01558 568703.LGG_00687 3.73e-214 593.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F4MI@33958|Lactobacillaceae 91061|Bacilli S ABC transporter substrate binding protein XK27_00670 - - ko:K01989,ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind NAGPHGKN_01559 568703.LGG_00689 3.27e-213 591.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F462@33958|Lactobacillaceae 91061|Bacilli S ABC transporter XK27_00670 - - ko:K01989,ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind NAGPHGKN_01560 568703.LGG_00690 1.68e-208 579.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,3F40J@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family WQ51_06230 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 NAGPHGKN_01561 568703.LGG_00691 4.78e-180 502.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,3F3NW@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein - - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran NAGPHGKN_01562 568703.LGG_00692 2.27e-220 608.0 COG0604@1|root,COG0604@2|Bacteria,1TPGR@1239|Firmicutes,4HACF@91061|Bacilli,3F5R8@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N NAGPHGKN_01563 568703.LGG_00693 0.0 1705.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F588@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus pacL3 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 NAGPHGKN_01564 568703.LGG_00695 8.07e-233 640.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,3F3X7@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 2 ykcC - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 NAGPHGKN_01565 568703.LGG_00696 0.0 1298.0 COG1807@1|root,COG1807@2|Bacteria,1TPGI@1239|Firmicutes,4HCEY@91061|Bacilli,3F5B1@33958|Lactobacillaceae 91061|Bacilli M Dolichyl-phosphate-mannose-protein mannosyltransferase ykcB - - - - - - - - - - - PMT_2 NAGPHGKN_01566 568703.LGG_00697 2.64e-94 275.0 2DTIF@1|root,33KHD@2|Bacteria,1UIGW@1239|Firmicutes,4ISGW@91061|Bacilli,3F7X1@33958|Lactobacillaceae 91061|Bacilli S GtrA-like protein - - - - - - - - - - - - GtrA NAGPHGKN_01567 1423732.BALS01000074_gene2115 1.59e-14 68.2 29QSF@1|root,30BSA@2|Bacteria,1U8JX@1239|Firmicutes,4IIHW@91061|Bacilli,3FB2A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01568 1423732.BALS01000048_gene2577 3.17e-11 64.7 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS NAGPHGKN_01569 568703.LGG_00700 6.13e-165 461.0 COG0745@1|root,COG0745@2|Bacteria,1V295@1239|Firmicutes,4HG3X@91061|Bacilli,3F3TH@33958|Lactobacillaceae 91061|Bacilli K cheY-homologous receiver domain ciaR - - ko:K14983 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C NAGPHGKN_01570 568703.LGG_00701 1.87e-307 838.0 COG5002@1|root,COG5002@2|Bacteria,1TS5K@1239|Firmicutes,4H9Y1@91061|Bacilli,3F49T@33958|Lactobacillaceae 91061|Bacilli T His Kinase A (phosphoacceptor) domain ciaH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K14982 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA NAGPHGKN_01571 568703.LGG_00702 1.99e-87 256.0 COG4918@1|root,COG4918@2|Bacteria,1VK6M@1239|Firmicutes,4HRFS@91061|Bacilli,3F7JD@33958|Lactobacillaceae 91061|Bacilli S Belongs to the HesB IscA family - - - - - - - - - - - - Fe-S_biosyn NAGPHGKN_01572 568703.LGG_00706 1.19e-156 439.0 COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HBVQ@91061|Bacilli,3F4H1@33958|Lactobacillaceae 91061|Bacilli C Nitroreductase family ydgI - - - - - - - - - - - Nitroreductase NAGPHGKN_01573 568703.LGG_00707 1.69e-258 709.0 COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,4HAU5@91061|Bacilli,3F9FE@33958|Lactobacillaceae 91061|Bacilli C IMP dehydrogenase / GMP reductase domain lldD - 1.13.12.4 ko:K00467 ko00620,map00620 - R00319 RC01312 ko00000,ko00001,ko01000 - - - FMN_dh NAGPHGKN_01576 888821.HMPREF9394_1863 1.29e-07 62.0 COG1396@1|root,COG1396@2|Bacteria,1UA46@1239|Firmicutes,4IKDX@91061|Bacilli,1WREM@1305|Streptococcus sanguinis 91061|Bacilli K Transcriptional regulator RggD rggD - - - - - - - - - - - - NAGPHGKN_01580 568703.LGG_00708 7.15e-232 639.0 COG1396@1|root,COG1396@2|Bacteria,1UIR0@1239|Firmicutes,4ISQY@91061|Bacilli 91061|Bacilli K sequence-specific DNA binding - - - - - - - - - - - - - NAGPHGKN_01581 568703.LGG_00709 6.52e-75 224.0 COG1695@1|root,COG1695@2|Bacteria,1VA94@1239|Firmicutes,4HKJS@91061|Bacilli,3F6I1@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family - - - ko:K10947 - - - - ko00000,ko03000 - - - PadR NAGPHGKN_01582 568703.LGG_00710 5.89e-66 200.0 COG4095@1|root,COG4095@2|Bacteria,1VBI9@1239|Firmicutes,4HMY5@91061|Bacilli,3F7IR@33958|Lactobacillaceae 91061|Bacilli S Sugar efflux transporter for intercellular exchange ygbF - - - - - - - - - - - MtN3_slv NAGPHGKN_01583 568703.LGG_00711 1.71e-64 196.0 2AVVX@1|root,31MPR@2|Bacteria,1U7Q2@1239|Firmicutes,4IHMD@91061|Bacilli,3FA04@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01584 568703.LGG_00712 7.49e-237 652.0 COG0604@1|root,COG0604@2|Bacteria,1TRNC@1239|Firmicutes,4HATC@91061|Bacilli,3F48F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily - - 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 NAGPHGKN_01585 568703.LGG_00713 5.83e-75 224.0 2BQ7I@1|root,32J28@2|Bacteria,1U7KB@1239|Firmicutes,4IHHD@91061|Bacilli,3F9V1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01586 568703.LGG_00714 6.82e-104 301.0 2CCJZ@1|root,303JM@2|Bacteria,1U58T@1239|Firmicutes,4IF00@91061|Bacilli,3F565@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01587 568703.LGG_00715 5.52e-265 727.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3F418@33958|Lactobacillaceae 91061|Bacilli S AI-2E family transporter XK27_05220 - - - - - - - - - - - AI-2E_transport NAGPHGKN_01588 568703.LGG_00716 1.99e-36 123.0 29QE7@1|root,30BDI@2|Bacteria,1U7YK@1239|Firmicutes,4IHVZ@91061|Bacilli,3FABT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01589 568703.LGG_00717 1e-129 370.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,3F3JG@33958|Lactobacillaceae 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 NAGPHGKN_01590 568703.LGG_00718 1.81e-98 287.0 29Q6R@1|root,30B5R@2|Bacteria,1U7KG@1239|Firmicutes,4IHHI@91061|Bacilli,3F9VA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01591 1423732.BALS01000001_gene1298 2.92e-19 84.7 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HB48@91061|Bacilli,3FCFH@33958|Lactobacillaceae 91061|Bacilli S Transporter, auxin efflux carrier (AEC) family protein mleP2 - - ko:K07088 - - - - ko00000 - - - Mem_trans NAGPHGKN_01592 568703.LGG_00719 8.71e-184 514.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HB48@91061|Bacilli,3FCFH@33958|Lactobacillaceae 91061|Bacilli S Transporter, auxin efflux carrier (AEC) family protein mleP2 - - ko:K07088 - - - - ko00000 - - - Mem_trans NAGPHGKN_01593 568703.LGG_00720 9.06e-136 385.0 COG1853@1|root,COG1853@2|Bacteria,1V999@1239|Firmicutes,4HK1X@91061|Bacilli,3FBBG@33958|Lactobacillaceae 91061|Bacilli S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct NAGPHGKN_01594 568703.LGG_00721 8.46e-177 498.0 29Q3E@1|root,30B22@2|Bacteria,1U7EG@1239|Firmicutes,4IHAC@91061|Bacilli,3F9H2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01595 568703.LGG_00722 4.09e-136 385.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,3F4KQ@33958|Lactobacillaceae 91061|Bacilli H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family fthC GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig NAGPHGKN_01596 568703.LGG_00723 2.41e-81 240.0 COG3189@1|root,COG3189@2|Bacteria,1VABH@1239|Firmicutes,4HKI2@91061|Bacilli,3F715@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function, DUF488 yeaO - - - - - - - - - - - DUF488 NAGPHGKN_01597 568703.LGG_00724 8.59e-221 609.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,3F5FV@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein - - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA NAGPHGKN_01598 568703.LGG_00725 6.96e-206 570.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli,3F5D2@33958|Lactobacillaceae 91061|Bacilli K LysR family mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - HTH_1,LysR_substrate NAGPHGKN_01599 568703.LGG_00726 0.0 1084.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4HBF1@91061|Bacilli,3F3RH@33958|Lactobacillaceae 91061|Bacilli C Malic enzyme mleS - 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 - R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 - - - Malic_M,malic NAGPHGKN_01600 568703.LGG_00727 8.81e-218 603.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HDX5@91061|Bacilli,3F3S0@33958|Lactobacillaceae 91061|Bacilli S Sodium Bile acid symporter family mleP - - ko:K07088 - - - - ko00000 - - - Mem_trans NAGPHGKN_01601 568703.LGG_01272 3.09e-148 419.0 COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,4HF14@91061|Bacilli,3F3WC@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein aatB - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 NAGPHGKN_01602 568703.LGG_01272 3.16e-31 116.0 COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,4HF14@91061|Bacilli,3F3WC@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein aatB - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 NAGPHGKN_01603 568703.LGG_01271 1.29e-143 405.0 COG1126@1|root,COG1126@2|Bacteria,1UYAZ@1239|Firmicutes,4HE6M@91061|Bacilli,3F4GP@33958|Lactobacillaceae 91061|Bacilli E ABC transporter glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran NAGPHGKN_01604 568703.LGG_01270 2.77e-141 400.0 COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli,3F3VF@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease yecS_2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 NAGPHGKN_01605 568703.LGG_01269 6.07e-182 507.0 COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,4HB2F@91061|Bacilli,3F3U8@33958|Lactobacillaceae 91061|Bacilli D Belongs to the ParA family minD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03609 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA NAGPHGKN_01606 568703.LGG_01268 8.93e-144 406.0 COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,4HBTI@91061|Bacilli,3F61V@33958|Lactobacillaceae 91061|Bacilli D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization minC GO:0000910,GO:0003674,GO:0004857,GO:0007049,GO:0007105,GO:0008150,GO:0009987,GO:0022402,GO:0030234,GO:0031333,GO:0032271,GO:0032272,GO:0032506,GO:0043086,GO:0043254,GO:0044087,GO:0044092,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0065009,GO:0098772 - ko:K03610 - - - - ko00000,ko03036,ko04812 - - - MinC_C NAGPHGKN_01607 568703.LGG_01267 2.13e-113 326.0 COG2891@1|root,COG2891@2|Bacteria,1VEV7@1239|Firmicutes,4HPAC@91061|Bacilli,3F6PG@33958|Lactobacillaceae 91061|Bacilli M rod shape-determining protein MreD mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD NAGPHGKN_01608 568703.LGG_01266 5.62e-193 536.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,3F3MC@33958|Lactobacillaceae 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC NAGPHGKN_01609 568703.LGG_01265 6.84e-229 631.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F3ZV@33958|Lactobacillaceae 91061|Bacilli D cell shape determining protein MreB mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl NAGPHGKN_01610 568703.LGG_01264 2.01e-151 427.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,3F5IM@33958|Lactobacillaceae 91061|Bacilli L DNA repair protein radC - - ko:K03630 - - - - ko00000 - - - RadC NAGPHGKN_01611 568703.LGG_01263 1.63e-147 416.0 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli,3F56K@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 NAGPHGKN_01612 568703.LGG_01262 5.13e-304 829.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,3F498@33958|Lactobacillaceae 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M NAGPHGKN_01613 568703.LGG_01261 0.0 1793.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,3F3RB@33958|Lactobacillaceae 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 NAGPHGKN_01614 568703.LGG_01260 3.97e-149 420.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HWTS@91061|Bacilli,3F9GZ@33958|Lactobacillaceae 91061|Bacilli K CoA binding domain - - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N NAGPHGKN_01615 568703.LGG_01259 1.73e-288 788.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,3F3N0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI NAGPHGKN_01616 568703.LGG_01258 3.81e-275 753.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,3F4CD@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 NAGPHGKN_01617 568703.LGG_01257 0.0 1026.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,3F47K@33958|Lactobacillaceae 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA NAGPHGKN_01618 568703.LGG_01256 6.83e-109 313.0 COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,3F6NT@33958|Lactobacillaceae 91061|Bacilli T GAF domain-containing protein yebR - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 NAGPHGKN_01619 568703.LGG_01255 5.31e-143 403.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,3F3P0@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 NAGPHGKN_01621 1449336.JQLO01000001_gene288 0.0 951.0 COG1061@1|root,COG1061@2|Bacteria,1TPWX@1239|Firmicutes,4HBBG@91061|Bacilli 91061|Bacilli KL Helicase conserved C-terminal domain - - - - - - - - - - - - Helicase_C NAGPHGKN_01622 1449336.JQLO01000001_gene289 2.45e-175 520.0 28HBW@1|root,2Z7NV@2|Bacteria,1TSAK@1239|Firmicutes,4HFWD@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF1998) - - - - - - - - - - - - DUF1998 NAGPHGKN_01623 1449336.JQLO01000001_gene286 2.14e-164 475.0 COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,4HEJQ@91061|Bacilli 91061|Bacilli H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase NAGPHGKN_01624 568703.LGG_01252 1.13e-289 793.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4IPPJ@91061|Bacilli,3FBDD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 NAGPHGKN_01625 568703.LGG_01251 2.4e-180 501.0 COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,3F4PK@33958|Lactobacillaceae 91061|Bacilli S peptidase C26 puuD - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 NAGPHGKN_01626 568703.LGG_01249 0.0 1386.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,3F415@33958|Lactobacillaceae 91061|Bacilli K Tex-like protein N-terminal domain protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF NAGPHGKN_01627 543734.LCABL_14510 3.68e-106 311.0 COG0454@1|root,COG0456@2|Bacteria,1U91G@1239|Firmicutes,4IJ1J@91061|Bacilli,3F938@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 NAGPHGKN_01628 568703.LGG_01242 4.64e-188 536.0 2ABP3@1|root,3114Y@2|Bacteria,1U53U@1239|Firmicutes,4IEV4@91061|Bacilli,3F4F6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01629 568703.LGG_01241 0.0 950.0 29NKB@1|root,309IA@2|Bacteria,1U557@1239|Firmicutes,4IEWP@91061|Bacilli,3F4RF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01630 568703.LGG_01240 1.83e-202 561.0 COG1131@1|root,COG1131@2|Bacteria,1TRM5@1239|Firmicutes,4HFBN@91061|Bacilli,3FC3M@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yvfR - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_01631 568703.LGG_01239 6.21e-165 463.0 COG0842@1|root,COG0842@2|Bacteria,1V7QG@1239|Firmicutes,4HFU4@91061|Bacilli,3F5Q7@33958|Lactobacillaceae 91061|Bacilli V ABC-2 type transporter XK27_09830 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 NAGPHGKN_01632 568703.LGG_01238 1.62e-256 704.0 COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli,3F3VR@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 NAGPHGKN_01633 568703.LGG_01237 2.93e-133 379.0 COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli,3F4VH@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Lux Regulon desR - - ko:K02479,ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg NAGPHGKN_01634 568703.LGG_01236 1.04e-135 388.0 2DBBC@1|root,2Z879@2|Bacteria,1V4KJ@1239|Firmicutes,4HTEU@91061|Bacilli,3F788@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01635 568703.LGG_01235 8.05e-197 546.0 COG1307@1|root,COG1307@2|Bacteria,1TYCV@1239|Firmicutes,4HD8F@91061|Bacilli,3F572@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 degV - - - - - - - - - - - DegV NAGPHGKN_01636 568703.LGG_01234 4.66e-110 316.0 COG0454@1|root,COG0456@2|Bacteria,1UI2W@1239|Firmicutes,4ISXQ@91061|Bacilli,3F8D7@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 NAGPHGKN_01637 568703.LGG_01233 1.72e-208 576.0 COG0454@1|root,COG0456@2|Bacteria,1V7Z2@1239|Firmicutes,4HPF8@91061|Bacilli,3F7HG@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 NAGPHGKN_01638 568703.LGG_01232 1.14e-107 312.0 COG2207@1|root,COG2207@2|Bacteria,1TSHF@1239|Firmicutes,4HFC7@91061|Bacilli,3F6S2@33958|Lactobacillaceae 91061|Bacilli K Psort location Cytoplasmic, score - - - - - - - - - - - - SAP NAGPHGKN_01639 568703.LGG_01232 5.9e-15 71.2 COG2207@1|root,COG2207@2|Bacteria,1TSHF@1239|Firmicutes,4HFC7@91061|Bacilli,3F6S2@33958|Lactobacillaceae 91061|Bacilli K Psort location Cytoplasmic, score - - - - - - - - - - - - SAP NAGPHGKN_01640 1423816.BACQ01000015_gene571 4.39e-06 47.0 29PRG@1|root,30APP@2|Bacteria,1U6YC@1239|Firmicutes,4IGSI@91061|Bacilli,3F8Q6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01641 568703.LGG_01231 2.24e-72 217.0 COG0599@1|root,COG0599@2|Bacteria,1VY4M@1239|Firmicutes,4IQRM@91061|Bacilli,3FBIK@33958|Lactobacillaceae 91061|Bacilli S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD NAGPHGKN_01642 568703.LGG_01230 1.63e-103 298.0 COG1917@1|root,COG1917@2|Bacteria,1V3TP@1239|Firmicutes,4HWR6@91061|Bacilli,3FBIH@33958|Lactobacillaceae 91061|Bacilli S Cupin domain yphH - - - - - - - - - - - Cupin_2 NAGPHGKN_01643 568703.LGG_01229 1.2e-207 574.0 COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HAZB@91061|Bacilli,3F3VP@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate NAGPHGKN_01644 568703.LGG_01228 2.07e-164 462.0 2EGU7@1|root,33AKD@2|Bacteria,1VMES@1239|Firmicutes,4HXVU@91061|Bacilli,3F7PT@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_4 NAGPHGKN_01645 568703.LGG_01227 4.56e-215 594.0 COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HAGA@91061|Bacilli,3FC3R@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system bcrA - - ko:K01990,ko:K19309 ko02010,map02010 M00254,M00747 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.131.1 - - ABC_tran NAGPHGKN_01646 568703.LGG_01226 1.38e-153 432.0 COG0745@1|root,COG0745@2|Bacteria,1UYA6@1239|Firmicutes,4IQ4T@91061|Bacilli,3F6RJ@33958|Lactobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C NAGPHGKN_01647 568703.LGG_01225 1.15e-204 567.0 COG0642@1|root,COG2205@2|Bacteria,1UZKD@1239|Firmicutes,4ITNE@91061|Bacilli,3FBXA@33958|Lactobacillaceae 91061|Bacilli T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA NAGPHGKN_01648 568703.LGG_01224 0.0 1081.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 NAGPHGKN_01649 568703.LGG_01223 9.53e-202 557.0 COG1387@1|root,COG1387@2|Bacteria,1V77D@1239|Firmicutes,4HHQX@91061|Bacilli,3F6HU@33958|Lactobacillaceae 91061|Bacilli E Histidinol phosphatase and related hydrolases of the PHP family hisK - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - - NAGPHGKN_01650 568703.LGG_01222 3.98e-171 478.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,3F488@33958|Lactobacillaceae 91061|Bacilli F deoxynucleoside kinase - - - - - - - - - - - - dNK NAGPHGKN_01651 568703.LGG_01221 1.02e-178 497.0 COG3201@1|root,COG3201@2|Bacteria,1VE5T@1239|Firmicutes,4HMNW@91061|Bacilli,3F3MB@33958|Lactobacillaceae 91061|Bacilli H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter NAGPHGKN_01652 568703.LGG_01220 5.95e-212 587.0 COG1028@1|root,COG1028@2|Bacteria,1VSDG@1239|Firmicutes,4HUM6@91061|Bacilli,3FB7Z@33958|Lactobacillaceae 91061|Bacilli IQ NAD dependent epimerase/dehydratase family - - - - - - - - - - - - adh_short NAGPHGKN_01653 568703.LGG_01219 1.4e-198 550.0 COG0225@1|root,COG0225@2|Bacteria,1TS05@1239|Firmicutes,4HAPI@91061|Bacilli,3FC52@33958|Lactobacillaceae 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine mrsA1 - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - EntA_Immun,PMSR NAGPHGKN_01654 568703.LGG_01218 2.9e-158 444.0 COG0406@1|root,COG0406@2|Bacteria,1U7EB@1239|Firmicutes,4IHA7@91061|Bacilli,3F9GU@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 NAGPHGKN_01655 568703.LGG_01217 1.01e-192 536.0 COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli,3F3X8@33958|Lactobacillaceae 91061|Bacilli E L-serine dehydratase, iron-sulfur-dependent, alpha subunit sdaAA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha NAGPHGKN_01656 568703.LGG_01216 2.93e-158 443.0 COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,4HBD6@91061|Bacilli,3F4UB@33958|Lactobacillaceae 91061|Bacilli E Serine dehydratase beta chain sdaAB - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - ACT,SDH_beta NAGPHGKN_01657 568703.LGG_01215 4.72e-141 398.0 COG4493@1|root,COG4493@2|Bacteria,1UY83@1239|Firmicutes,4HEDB@91061|Bacilli,3F62K@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0637 family yktB - - - - - - - - - - - DUF1054 NAGPHGKN_01658 568703.LGG_01214 1.63e-95 278.0 COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli,3F64D@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1694) XK27_05190 - - - - - - - - - - - DUF1694 NAGPHGKN_01659 568703.LGG_01213 0.0 1244.0 COG1181@1|root,COG1181@2|Bacteria,1UJ6D@1239|Firmicutes,4ITSZ@91061|Bacilli,3FBXN@33958|Lactobacillaceae 91061|Bacilli M Mur ligase middle domain protein - - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - - NAGPHGKN_01660 568703.LGG_01211 1.84e-302 827.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3WF@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N NAGPHGKN_01661 568703.LGG_01209 1.41e-53 168.0 2BNXR@1|root,32HMR@2|Bacteria,1U7ZC@1239|Firmicutes,4IHWQ@91061|Bacilli,3FACP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01662 568703.LGG_01208 6.47e-110 317.0 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,3F68T@33958|Lactobacillaceae 91061|Bacilli T universal stress protein uspA - - - - - - - - - - - Usp NAGPHGKN_01663 568703.LGG_01207 2.16e-206 571.0 COG1476@1|root,COG1476@2|Bacteria,1VMYH@1239|Firmicutes,4ISF0@91061|Bacilli,3F5QH@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3,TPR_8 NAGPHGKN_01664 568703.LGG_01206 3.54e-230 634.0 29SNM@1|root,30DU7@2|Bacteria,1V3Z9@1239|Firmicutes,4HHKX@91061|Bacilli,3F3VM@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 NAGPHGKN_01665 568703.LGG_01205 8.1e-87 255.0 COG5506@1|root,COG5506@2|Bacteria,1V8ID@1239|Firmicutes,4HJTQ@91061|Bacilli,3F7A5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1694) - - - - - - - - - - - - DUF1694 NAGPHGKN_01666 568703.LGG_01204 2.14e-36 122.0 29QHS@1|root,30BH8@2|Bacteria,1U84C@1239|Firmicutes,4II1T@91061|Bacilli,3FAIG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01668 568703.LGG_01203 0.0 960.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,3F44I@33958|Lactobacillaceae 91061|Bacilli O assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 NAGPHGKN_01669 568703.LGG_01202 1.42e-102 296.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,3F6WP@33958|Lactobacillaceae 91061|Bacilli C SUF system FeS assembly protein, NifU family nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N NAGPHGKN_01670 568703.LGG_01201 1.39e-281 770.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,3F3UP@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 NAGPHGKN_01671 568703.LGG_01200 1.21e-243 669.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,3F4BR@33958|Lactobacillaceae 91061|Bacilli O FeS assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 NAGPHGKN_01672 568703.LGG_01199 2.4e-183 509.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,3F3XT@33958|Lactobacillaceae 91061|Bacilli O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran NAGPHGKN_01673 568703.LGG_01198 5.58e-151 426.0 COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,4HBEV@91061|Bacilli,3F48A@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 NAGPHGKN_01674 568703.LGG_01197 9.88e-236 650.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,3F3U5@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL NAGPHGKN_01675 568703.LGG_01196 8.69e-192 533.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3F3WP@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 NAGPHGKN_01676 568703.LGG_01195 1.56e-189 527.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3F3WP@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 NAGPHGKN_01677 568703.LGG_01194 1.63e-266 731.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 NAGPHGKN_01678 568703.LGG_01193 1.41e-63 194.0 COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,3F7WB@33958|Lactobacillaceae 91061|Bacilli E glycine cleavage gcsH2 - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H NAGPHGKN_01679 568703.LGG_01192 1.35e-283 775.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,3F4J4@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE NAGPHGKN_01680 1423816.BACQ01000017_gene611 2.92e-42 138.0 2BQ47@1|root,30ACR@2|Bacteria,1U6GX@1239|Firmicutes,4IG94@91061|Bacilli,3F7W8@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2969) - - - - - - - - - - - - DUF2969 NAGPHGKN_01681 568703.LGG_01190 1.62e-72 217.0 COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli,3F7H1@33958|Lactobacillaceae 91061|Bacilli S Could be involved in insertion of integral membrane proteins into the membrane ytjA - - ko:K08998 - - - - ko00000 - - - Haemolytic NAGPHGKN_01682 568703.LGG_01189 5.48e-35 119.0 2EK0E@1|root,33DQZ@2|Bacteria,1VMAH@1239|Firmicutes,4I4NP@91061|Bacilli,3F8Q0@33958|Lactobacillaceae 91061|Bacilli S DNA-directed RNA polymerase subunit beta - - - - - - - - - - - - EpuA NAGPHGKN_01683 568703.LGG_01188 2.13e-230 635.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F463@33958|Lactobacillaceae 91061|Bacilli D Cell shape determining protein MreB Mrl mbl - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl NAGPHGKN_01684 1423732.BALS01000006_gene669 2.5e-43 141.0 COG4836@1|root,COG4836@2|Bacteria,1U2FR@1239|Firmicutes,4IC1C@91061|Bacilli,3F8YA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1146) - - - - - - - - - - - - DUF1146 NAGPHGKN_01685 568703.LGG_00891 5.78e-19 80.5 2BT3F@1|root,32N80@2|Bacteria,1U8CV@1239|Firmicutes,4IIAU@91061|Bacilli,3FAUG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01686 568703.LGG_01185 6.51e-83 246.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,3F6I6@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N NAGPHGKN_01687 568703.LGG_01184 0.0 908.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,3F3TF@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N NAGPHGKN_01689 568703.LGG_01182 1.78e-211 585.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,3F40E@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt NAGPHGKN_01690 568703.LGG_01181 0.0 983.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,3F3R4@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N NAGPHGKN_01691 568703.LGG_01180 4.59e-115 331.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,3F5TZ@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP NAGPHGKN_01692 568703.LGG_01179 8.51e-72 220.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,3F5M8@33958|Lactobacillaceae 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B NAGPHGKN_01693 568703.LGG_01178 3.01e-36 123.0 COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli,3F82A@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C NAGPHGKN_01694 568703.LGG_01177 4.11e-161 452.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,3F3RE@33958|Lactobacillaceae 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A NAGPHGKN_01695 568703.LGG_01175 2.46e-127 363.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,3F4M0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase NAGPHGKN_01696 568703.LGG_01174 1.29e-297 811.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,3F4C1@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT NAGPHGKN_01697 568703.LGG_01173 7.03e-246 675.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,3F3T1@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC NAGPHGKN_01698 568703.LGG_01172 1.63e-196 545.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,3F460@33958|Lactobacillaceae 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS NAGPHGKN_01699 568703.LGG_01171 3.51e-251 690.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,3F3Q0@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 NAGPHGKN_01700 568703.LGG_01169 8.22e-144 405.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,3F4UE@33958|Lactobacillaceae 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK NAGPHGKN_01701 568703.LGG_01168 0.0 904.0 COG0770@1|root,COG0770@2|Bacteria,1TRG9@1239|Firmicutes,4HAMY@91061|Bacilli,3FBS5@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF1727) murE2 - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - DUF1727,Mur_ligase_M NAGPHGKN_01702 568703.LGG_01167 2.09e-244 671.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,3FBDZ@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase ampC - - - - - - - - - - - Beta-lactamase NAGPHGKN_01703 568703.LGG_01166 9.19e-209 577.0 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli,3F62I@33958|Lactobacillaceae 91061|Bacilli S glyoxalase catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase NAGPHGKN_01704 568703.LGG_01165 4.13e-178 496.0 COG0431@1|root,COG0431@2|Bacteria,1VBJA@1239|Firmicutes,4HSVK@91061|Bacilli,3F41J@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red NAGPHGKN_01705 568703.LGG_01164 0.0 1207.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yfiC - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NAGPHGKN_01706 568703.LGG_01163 0.0 1086.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ycfI - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NAGPHGKN_01707 568703.LGG_01162 5.26e-155 435.0 COG1309@1|root,COG1309@2|Bacteria,1V6CF@1239|Firmicutes,4IQ0F@91061|Bacilli,3FBF7@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N NAGPHGKN_01708 568703.LGG_01161 3.56e-168 471.0 COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HD4C@91061|Bacilli,3F50R@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family pgm7 - - - - - - - - - - - His_Phos_1 NAGPHGKN_01713 568703.LGG_01158 0.0 981.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD2 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 NAGPHGKN_01714 1423816.BACQ01000018_gene641 8e-247 682.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,3F4F9@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator yttB - - - - - - - - - - - MFS_1 NAGPHGKN_01715 568703.LGG_01155 1.56e-25 94.4 29PYH@1|root,30AWY@2|Bacteria,1U77Q@1239|Firmicutes,4IH2I@91061|Bacilli,3F930@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01723 568703.LGG_01149 4e-110 316.0 COG0590@1|root,COG0590@2|Bacteria,1V7G0@1239|Firmicutes,4HMR9@91061|Bacilli,3F6S6@33958|Lactobacillaceae 91061|Bacilli FJ MafB19-like deaminase guaD - - - - - - - - - - - MafB19-deam,dCMP_cyt_deam_1 NAGPHGKN_01724 568703.LGG_01148 3.12e-220 607.0 COG0673@1|root,COG0673@2|Bacteria,1UZRV@1239|Firmicutes,4HEWB@91061|Bacilli,3F4BX@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold ysjB - - ko:K03810 - - - - ko00000 - - - GFO_IDH_MocA NAGPHGKN_01725 568703.LGG_01147 6.51e-293 798.0 COG0438@1|root,COG0438@2|Bacteria,1VIZB@1239|Firmicutes,4HU4N@91061|Bacilli,3F9Q1@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glyco_trans_1_4 NAGPHGKN_01726 568703.LGG_01146 7.92e-102 303.0 COG2433@1|root,COG2433@2|Bacteria,1VH0K@1239|Firmicutes,4ITND@91061|Bacilli,3FBX9@33958|Lactobacillaceae 91061|Bacilli S Pfam Transposase IS66 - - - - - - - - - - - - - NAGPHGKN_01727 568703.LGG_01145 7.26e-183 511.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HHHQ@91061|Bacilli,3F4MB@33958|Lactobacillaceae 91061|Bacilli F DNA/RNA non-specific endonuclease - - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 NAGPHGKN_01728 568703.LGG_01144 3.16e-50 159.0 COG1359@1|root,COG1359@2|Bacteria,1VG4T@1239|Firmicutes,4HPNQ@91061|Bacilli,3F7H6@33958|Lactobacillaceae 91061|Bacilli S Antibiotic biosynthesis monooxygenase ycnE GO:0003674,GO:0003824 - - - - - - - - - - ABM NAGPHGKN_01730 568703.LGG_01085 0.0 889.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,3F3XK@33958|Lactobacillaceae 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI NAGPHGKN_01731 568703.LGG_01084 5.43e-195 541.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,3F4K2@33958|Lactobacillaceae 91061|Bacilli U sugar transport glcU GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659 - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport NAGPHGKN_01732 568703.LGG_01083 3.74e-142 401.0 COG4767@1|root,COG4767@2|Bacteria,1VK3A@1239|Firmicutes,4HPCD@91061|Bacilli,3F5EN@33958|Lactobacillaceae 91061|Bacilli V VanZ like family vanZ - - - - - - - - - - - VanZ NAGPHGKN_01733 568703.LGG_01082 0.0 1462.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase NAGPHGKN_01734 568703.LGG_01081 1.37e-165 464.0 29Z4F@1|root,30M23@2|Bacteria,1U7B2@1239|Firmicutes,4IH62@91061|Bacilli,3F98Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01735 568703.LGG_01080 1.8e-134 380.0 29PYD@1|root,30AWT@2|Bacteria,1U77H@1239|Firmicutes,4IH2B@91061|Bacilli,3F92N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01736 568703.LGG_01079 1.74e-315 858.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,3F48P@33958|Lactobacillaceae 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 NAGPHGKN_01737 568703.LGG_01078 2.43e-263 721.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,3F3YV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK2 - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp NAGPHGKN_01738 568703.LGG_01077 1.87e-304 832.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,3F3Y7@33958|Lactobacillaceae 91061|Bacilli F xanthine permease pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16169 - - - - ko00000,ko02000 2.A.40,2.A.40.3.1 - iSB619.SA_RS02140 Xan_ur_permease NAGPHGKN_01739 568703.LGG_01076 7.6e-131 372.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,3F49S@33958|Lactobacillaceae 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran NAGPHGKN_01740 568703.LGG_01075 1.84e-147 415.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIY4@91061|Bacilli,3F584@33958|Lactobacillaceae 91061|Bacilli NU mannosyl-glycoprotein acmA - 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,SH3_8,YceG NAGPHGKN_01741 568703.LGG_01074 2.8e-105 305.0 COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,4HH45@91061|Bacilli,3F7GI@33958|Lactobacillaceae 91061|Bacilli K GNAT family yvbK - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 NAGPHGKN_01742 1071400.LBUCD034_0299 1.73e-35 122.0 COG2336@1|root,COG2336@2|Bacteria,1VPRD@1239|Firmicutes,4HRKY@91061|Bacilli,3F8B3@33958|Lactobacillaceae 91061|Bacilli T PFAM SpoVT AbrB - - - - - - - - - - - - - NAGPHGKN_01743 568703.LGG_01072 6.22e-43 139.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3F7FW@33958|Lactobacillaceae 91061|Bacilli K Cold shock protein cspC - - ko:K03704 - - - - ko00000,ko03000 - - - CSD NAGPHGKN_01744 568703.LGG_01071 2.84e-215 596.0 COG4129@1|root,COG4129@2|Bacteria,1TP2T@1239|Firmicutes,4HAWV@91061|Bacilli,3F54Y@33958|Lactobacillaceae 91061|Bacilli S Putative aromatic acid exporter C-terminal domain yqjA - - - - - - - - - - - ArAE_1,ArAE_1_C NAGPHGKN_01745 568703.LGG_01070 5.01e-142 402.0 28T4I@1|root,2ZFDJ@2|Bacteria,1W6RG@1239|Firmicutes,4HZG4@91061|Bacilli,3F88M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - YkyA NAGPHGKN_01746 568703.LGG_01069 4.96e-219 604.0 COG1216@1|root,COG1216@2|Bacteria,1UHWE@1239|Firmicutes,4ISA4@91061|Bacilli,3F3JX@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 2 family protein yfdH - - ko:K12999 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 NAGPHGKN_01747 1423816.BACQ01000064_gene2455 3.76e-107 315.0 COG3177@1|root,COG3177@2|Bacteria,1V3AX@1239|Firmicutes,4HVK3@91061|Bacilli,3F4YX@33958|Lactobacillaceae 91061|Bacilli S Fic/DOC family - - - - - - - - - - - - Fic NAGPHGKN_01748 568703.LGG_01068 0.0 1071.0 COG5617@1|root,COG5617@2|Bacteria,1VS0Z@1239|Firmicutes,4HJQE@91061|Bacilli,3FBX8@33958|Lactobacillaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - PTPS_related NAGPHGKN_01749 568703.LGG_01066 0.0 1637.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HCR9@91061|Bacilli,3FC7P@33958|Lactobacillaceae 91061|Bacilli S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO NAGPHGKN_01750 568703.LGG_01065 0.0 1078.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system bglH - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NAGPHGKN_01751 568703.LGG_01064 7.09e-278 763.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 NAGPHGKN_01752 568703.LGG_01064 1.59e-70 225.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 NAGPHGKN_01753 1221537.B807_590 1.75e-269 780.0 COG0653@1|root,COG0653@2|Bacteria,1TRJA@1239|Firmicutes,4HCH0@91061|Bacilli,3F50U@33958|Lactobacillaceae 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA2 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SecA_DEAD,SecA_PP_bind,SecA_SW NAGPHGKN_01754 1302286.BAOT01000018_gene1052 1.06e-39 150.0 COG0438@1|root,COG0438@2|Bacteria,1V8J0@1239|Firmicutes,4HITN@91061|Bacilli,3FBH7@33958|Lactobacillaceae 91061|Bacilli M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - NAGPHGKN_01755 1231336.L248_0821 2.08e-58 195.0 COG1442@1|root,COG1442@2|Bacteria,1VE28@1239|Firmicutes,4HMZE@91061|Bacilli,3F758@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 NAGPHGKN_01756 1423732.BALS01000059_gene2808 2.19e-149 427.0 COG1442@1|root,COG1442@2|Bacteria 2|Bacteria M lipopolysaccharide 3-alpha-galactosyltransferase activity - GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0016740,GO:0016757,GO:0043170,GO:0044238,GO:0071704,GO:1901576 - - - - - - - - - - GT-D,Glyco_transf_8 NAGPHGKN_01757 568703.LGG_01062 1.53e-216 598.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,3F45A@33958|Lactobacillaceae 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase NAGPHGKN_01758 568703.LGG_01061 6.33e-253 694.0 COG1577@1|root,COG1577@2|Bacteria,1TPKP@1239|Firmicutes,4HC93@91061|Bacilli,3F3RZ@33958|Lactobacillaceae 91061|Bacilli I phosphomevalonate kinase mvaK2 - 2.7.4.2 ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R03245 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N NAGPHGKN_01759 568703.LGG_01060 2.12e-40 133.0 2BQ1G@1|root,32IVS@2|Bacteria,1U82T@1239|Firmicutes,4II07@91061|Bacilli,3FAGJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01761 568703.LGG_01057 9.28e-248 680.0 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,4HGSR@91061|Bacilli,3FBSG@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 NAGPHGKN_01762 568703.LGG_01056 2.34e-204 564.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,3F3MK@33958|Lactobacillaceae 91061|Bacilli E Methionine Aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 NAGPHGKN_01763 1423732.BALS01000059_gene2802 7.47e-76 229.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli,3F6HY@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin fld - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 NAGPHGKN_01764 568703.LGG_01054 1.82e-229 633.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,3F4TC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0761 family rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB NAGPHGKN_01765 568703.LGG_01053 0.0 904.0 COG4320@1|root,COG4320@2|Bacteria,1UCBA@1239|Firmicutes,4HBCI@91061|Bacilli,3F3JA@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2252) - - - ko:K13730 ko05100,map05100 - - - ko00000,ko00001 - - - DUF2252 NAGPHGKN_01766 1423732.BALS01000048_gene2577 6.23e-07 52.4 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS NAGPHGKN_01768 568703.LGG_01051 1.41e-142 402.0 COG1309@1|root,COG1309@2|Bacteria,1V8EE@1239|Firmicutes,4HJF2@91061|Bacilli,3FBGB@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N,WHG NAGPHGKN_01769 568703.LGG_01050 1.35e-304 829.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,3F53R@33958|Lactobacillaceae 91061|Bacilli E Thermophilic metalloprotease (M29) pepS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 NAGPHGKN_01770 568703.LGG_01049 0.0 1163.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3F4PY@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind NAGPHGKN_01771 1291743.LOSG293_160010 5.65e-07 57.4 arCOG05209@1|root,31PIN@2|Bacteria,1V5G2@1239|Firmicutes,4HIRV@91061|Bacilli,3F6X9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01773 568703.LGG_01047 1.1e-93 273.0 2DQNY@1|root,337UX@2|Bacteria,1VEZ0@1239|Firmicutes,4HPE2@91061|Bacilli,3F875@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF3284) - - - - - - - - - - - - DUF3284 NAGPHGKN_01774 568703.LGG_01045 2.05e-63 194.0 COG1447@1|root,COG1447@2|Bacteria,1U7M6@1239|Firmicutes,4IHIA@91061|Bacilli,3F9W9@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit - - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA NAGPHGKN_01775 568703.LGG_01044 5.1e-301 822.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,3F4K8@33958|Lactobacillaceae 91061|Bacilli L DEAD DEAH box helicase yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C NAGPHGKN_01776 568703.LGG_01043 1.14e-228 629.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,3F4EV@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase mocA - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C NAGPHGKN_01777 568703.LGG_01042 3.98e-81 240.0 2EGZM@1|root,33ARR@2|Bacteria,1VNS7@1239|Firmicutes,4HSZW@91061|Bacilli,3F83W@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4828) - - - - - - - - - - - - DUF4828 NAGPHGKN_01778 568703.LGG_01040 3.83e-79 235.0 COG5294@1|root,COG5294@2|Bacteria,1VF0I@1239|Firmicutes,4HPC2@91061|Bacilli,3F83V@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 NAGPHGKN_01779 568703.LGG_01039 1.28e-171 479.0 COG3757@1|root,COG3757@2|Bacteria,1V484@1239|Firmicutes,4HJNJ@91061|Bacilli,3FC1I@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,PG_binding_1 NAGPHGKN_01780 568703.LGG_01038 1.05e-40 134.0 29PRV@1|root,30AQ2@2|Bacteria,1U6Z0@1239|Firmicutes,4IGT9@91061|Bacilli,3F8R4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01781 568703.LGG_01037 1.95e-166 471.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli,3F4HV@33958|Lactobacillaceae 91061|Bacilli O prohibitin homologues hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 NAGPHGKN_01782 568703.LGG_01036 7.88e-211 582.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,3F4II@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 yitS - - - - - - - - - - - DegV NAGPHGKN_01783 568703.LGG_01034 7.53e-104 300.0 COG0454@1|root,COG0456@2|Bacteria,1VBAA@1239|Firmicutes,4HN0D@91061|Bacilli,3F9SM@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 NAGPHGKN_01784 568703.LGG_01033 0.0 1254.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F9J0@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N NAGPHGKN_01785 568703.LGG_01032 2.97e-211 583.0 COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,4HDT2@91061|Bacilli,3F59Q@33958|Lactobacillaceae 91061|Bacilli S Polyphosphate nucleotide phosphotransferase, PPK2 family - - - - - - - - - - - - PPK2 NAGPHGKN_01786 568703.LGG_01031 8.04e-190 527.0 COG0561@1|root,COG0561@2|Bacteria,1VAFW@1239|Firmicutes,4HWQV@91061|Bacilli,3FC8C@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 NAGPHGKN_01787 568703.LGG_01030 8.36e-277 758.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,3F4F9@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator yttB - - - - - - - - - - - MFS_1 NAGPHGKN_01788 568703.LGG_01022 0.0 870.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F41R@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_2 - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr NAGPHGKN_01789 568703.LGG_01021 1.42e-247 679.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,3F447@33958|Lactobacillaceae 91061|Bacilli G Lipid kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat NAGPHGKN_01790 568703.LGG_01020 0.0 961.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,3F44H@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey NAGPHGKN_01791 568703.LGG_01019 0.0 931.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,3F4BK@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase NAGPHGKN_01792 568703.LGG_01018 1.26e-61 189.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,3F7XB@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln NAGPHGKN_01793 568703.LGG_01017 2.36e-260 714.0 COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,3F3KI@33958|Lactobacillaceae 91061|Bacilli S sex pheromone camS - - - - - - - - - - - CamS NAGPHGKN_01794 568703.LGG_01016 0.0 1312.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,3F43C@33958|Lactobacillaceae 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 NAGPHGKN_01795 568703.LGG_01015 0.0 1471.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3F400@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C NAGPHGKN_01796 568703.LGG_01014 1.3e-51 164.0 COG4269@1|root,COG4269@2|Bacteria,1VA3P@1239|Firmicutes,4HK0T@91061|Bacilli,3F733@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF898) - - - - - - - - - - - - DUF898 NAGPHGKN_01797 568703.LGG_01013 2.4e-163 459.0 COG2755@1|root,COG2755@2|Bacteria,1VIWQ@1239|Firmicutes,4HPR5@91061|Bacilli,3F64H@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL,Lipase_GDSL_2 NAGPHGKN_01798 568703.LGG_01012 4.45e-173 490.0 COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,3FBEE@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic tcaA - - ko:K21463 - - - - ko00000 - - - zf-ribbon_3,zinc_ribbon_2 NAGPHGKN_01800 568703.LGG_01010 0.0 868.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,3F3WN@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA polymerase type-Y family polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH NAGPHGKN_01801 568703.LGG_01009 1.41e-77 231.0 28WF1@1|root,2ZIF8@2|Bacteria,1W2PF@1239|Firmicutes,4HZUK@91061|Bacilli,3F8BE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01802 568703.LGG_01008 1.84e-77 234.0 29Q3G@1|root,30B24@2|Bacteria,1U7EM@1239|Firmicutes,4IHAG@91061|Bacilli,3F9HE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01803 568703.LGG_01007 1.49e-93 273.0 COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,4HFRC@91061|Bacilli,3F6TJ@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0735 family pheB - 5.4.99.5 ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27910 ACT,ACT_4 NAGPHGKN_01804 568703.LGG_01006 2.21e-42 138.0 29QKN@1|root,30BKA@2|Bacteria,1U89K@1239|Firmicutes,4II7H@91061|Bacilli,3FAQS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01805 568703.LGG_01005 1.9e-121 347.0 COG3153@1|root,COG3153@2|Bacteria,1W0Z5@1239|Firmicutes,4HZAD@91061|Bacilli,3FBB4@33958|Lactobacillaceae 91061|Bacilli S acetyltransferase - - - - - - - - - - - - Acetyltransf_1 NAGPHGKN_01806 568703.LGG_01004 0.0 959.0 COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4IS6U@91061|Bacilli,3FBSR@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA NAGPHGKN_01807 568703.LGG_01003 3.15e-173 483.0 COG0745@1|root,COG0745@2|Bacteria,1TQUQ@1239|Firmicutes,4HAXP@91061|Bacilli,3F3QZ@33958|Lactobacillaceae 91061|Bacilli K response regulator yclJ - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C NAGPHGKN_01808 568703.LGG_01002 1.55e-91 267.0 COG5658@1|root,2ZY3R@2|Bacteria,1VKM4@1239|Firmicutes,4I0CM@91061|Bacilli,3F6IB@33958|Lactobacillaceae 91061|Bacilli S SdpI/YhfL protein family - - - - - - - - - - - - SdpI NAGPHGKN_01810 543734.LCABL_27460 1.26e-52 168.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,3F6YZ@33958|Lactobacillaceae 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL NAGPHGKN_01811 1423732.BALS01000106_gene437 1.4e-35 122.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein ytgB - - - - - - - - - - - Transgly_assoc NAGPHGKN_01812 543734.LCABL_30970 2.3e-23 89.0 2A7T8@1|root,30WSA@2|Bacteria,1U6PB@1239|Firmicutes,4IGGB@91061|Bacilli,3F8SR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01814 1196324.A374_08749 3.8e-17 77.0 2C6FI@1|root,2ZGHD@2|Bacteria,1W3UJ@1239|Firmicutes 1239|Firmicutes S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join NAGPHGKN_01815 568703.LGG_02902 1.88e-62 191.0 28TB1@1|root,2ZIBE@2|Bacteria,1W1M4@1239|Firmicutes,4I0N3@91061|Bacilli 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 NAGPHGKN_01816 543734.LCABL_30950 0.0 953.0 COG3740@1|root,COG4653@1|root,COG3740@2|Bacteria,COG4653@2|Bacteria,1TSYM@1239|Firmicutes,4HE4V@91061|Bacilli,3F5ZB@33958|Lactobacillaceae 91061|Bacilli S Phage capsid family - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78,Phage_capsid NAGPHGKN_01817 568703.LGG_02900 5.66e-277 758.0 COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,4HHWD@91061|Bacilli,3F42D@33958|Lactobacillaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal NAGPHGKN_01818 568703.LGG_02899 6.06e-29 103.0 2BTIA@1|root,32NQT@2|Bacteria,1U8EJ@1239|Firmicutes,4IICE@91061|Bacilli,3FAWA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01819 568703.LGG_02898 0.0 1110.0 COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,4HAXI@91061|Bacilli,3F51U@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name terL - - - - - - - - - - - Terminase_1 NAGPHGKN_01820 568703.LGG_02897 9.4e-105 303.0 COG3747@1|root,COG3747@2|Bacteria,1VJ8S@1239|Firmicutes,4HQ9R@91061|Bacilli,3F4WP@33958|Lactobacillaceae 91061|Bacilli L Phage terminase, small subunit terS - - - - - - - - - - - Terminase_4 NAGPHGKN_01822 565653.EGBG_02354 2.9e-174 504.0 COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4HBTB@91061|Bacilli,4B0SV@81852|Enterococcaceae 91061|Bacilli S D5 N terminal like - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol NAGPHGKN_01823 568703.LGG_02893 5.43e-190 528.0 COG3598@1|root,COG3598@2|Bacteria,1VVT1@1239|Firmicutes,4ITNM@91061|Bacilli,3FBJ8@33958|Lactobacillaceae 91061|Bacilli L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - PriCT_1,Prim-Pol NAGPHGKN_01824 568703.LGG_02892 1.18e-34 118.0 2AIKE@1|root,3192N@2|Bacteria,1U847@1239|Firmicutes,4II1N@91061|Bacilli,3FAIA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01825 1423732.BALS01000058_gene2818 2.89e-43 142.0 29QB8@1|root,30BAG@2|Bacteria,1U7TH@1239|Firmicutes,4IHQZ@91061|Bacilli,3FA5K@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01826 568703.LGG_02890 1.85e-36 123.0 29QP0@1|root,30BNN@2|Bacteria,1U8DG@1239|Firmicutes,4IIBE@91061|Bacilli,3FAV3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01827 568703.LGG_02889 1.6e-21 84.3 29QI2@1|root,30BHH@2|Bacteria,1U84R@1239|Firmicutes,4II26@91061|Bacilli,3FAIV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01828 543734.LCABL_30820 8.37e-42 137.0 2BPNT@1|root,32IFV@2|Bacteria,1U81M@1239|Firmicutes,4IHZ0@91061|Bacilli,3FAF0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01829 1423816.BACQ01000022_gene758 1.85e-58 181.0 2BNWZ@1|root,32HKX@2|Bacteria,1U7ZA@1239|Firmicutes,4IHWN@91061|Bacilli,3FACM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01830 1122963.AUHB01000010_gene1712 2.32e-06 51.6 COG3655@1|root,COG3655@2|Bacteria,1N6VH@1224|Proteobacteria,2UFAM@28211|Alphaproteobacteria,36YWM@31993|Methylocystaceae 28211|Alphaproteobacteria K Cro/C1-type HTH DNA-binding domain - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 NAGPHGKN_01831 1423816.BACQ01000022_gene760 1.01e-273 749.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family sip - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase NAGPHGKN_01832 568703.LGG_01001 0.0 1549.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,3F3RU@33958|Lactobacillaceae 91061|Bacilli G alpha-galactosidase rafA - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase NAGPHGKN_01833 568703.LGG_01000 2.93e-207 573.0 COG0204@1|root,COG0204@2|Bacteria,1V2F4@1239|Firmicutes,4IF2T@91061|Bacilli,3F5FU@33958|Lactobacillaceae 91061|Bacilli I Phosphate acyltransferases arbZ - - - - - - - - - - - Acyltransferase NAGPHGKN_01834 568703.LGG_00999 6.11e-229 630.0 COG1442@1|root,COG1442@2|Bacteria,1UY8Y@1239|Firmicutes,4HBAE@91061|Bacilli,3F4YJ@33958|Lactobacillaceae 91061|Bacilli M family 8 arbY - - - - - - - - - - - Glyco_transf_8 NAGPHGKN_01835 568703.LGG_00998 1.36e-210 580.0 COG1442@1|root,COG1442@2|Bacteria,1UY4M@1239|Firmicutes,4IEY6@91061|Bacilli,3F4YZ@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 8 arbx - - - - - - - - - - - Glyco_transf_8 NAGPHGKN_01836 568703.LGG_00997 1.34e-184 513.0 COG0204@1|root,COG0204@2|Bacteria,1V6NX@1239|Firmicutes,4IQ5I@91061|Bacilli,3FBFU@33958|Lactobacillaceae 91061|Bacilli I Phosphate acyltransferases arbV - - - - - - - - - - - Acyltransferase NAGPHGKN_01837 568703.LGG_00996 1.03e-314 858.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease cycA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease NAGPHGKN_01838 568703.LGG_00995 1.58e-96 281.0 2BH80@1|root,32B99@2|Bacteria,1U70M@1239|Firmicutes,4IGUY@91061|Bacilli,3F8TH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01839 568703.LGG_00994 3.7e-235 647.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli,3F4CI@33958|Lactobacillaceae 91061|Bacilli L N-6 DNA Methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase NAGPHGKN_01840 568703.LGG_00993 1.84e-65 199.0 2BTEK@1|root,32NKT@2|Bacteria,1U8E6@1239|Firmicutes,4IIC3@91061|Bacilli,3FAVY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01841 568703.LGG_00992 2.14e-105 304.0 29Q7R@1|root,30B6S@2|Bacteria,1U7MZ@1239|Firmicutes,4IHJ8@91061|Bacilli,3F9XI@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - - NAGPHGKN_01842 568703.LGG_00991 3.45e-63 194.0 2AHWS@1|root,3189N@2|Bacteria,1U7TM@1239|Firmicutes,4IHR3@91061|Bacilli,3FA5S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01844 568703.LGG_00989 2e-64 197.0 2BKDX@1|root,32EUM@2|Bacteria,1U7Q0@1239|Firmicutes,4IHMB@91061|Bacilli,3FA01@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - - NAGPHGKN_01845 568703.LGG_00988 1.91e-211 586.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,3F3S9@33958|Lactobacillaceae 91061|Bacilli NU type II secretion system comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF NAGPHGKN_01846 568703.LGG_00987 5.7e-183 511.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,3F4HY@33958|Lactobacillaceae 91061|Bacilli NU Type II IV secretion system protein comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE NAGPHGKN_01847 568703.LGG_00986 1.75e-170 476.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,3F4WF@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg NAGPHGKN_01848 568703.LGG_00985 1.8e-119 340.0 COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,4HMDE@91061|Bacilli,3F57S@33958|Lactobacillaceae 91061|Bacilli S VanZ like family - - - - - - - - - - - - VanZ NAGPHGKN_01849 568703.LGG_00984 0.0 1203.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,3F4ZV@33958|Lactobacillaceae 91061|Bacilli E Oligopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N NAGPHGKN_01850 568703.LGG_00983 0.0 1160.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,3F467@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS NAGPHGKN_01851 568703.LGG_00982 0.0 882.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,3F3W5@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV NAGPHGKN_01852 568703.LGG_00981 2.39e-221 615.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,3F41C@33958|Lactobacillaceae 91061|Bacilli S YbbR-like protein ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR NAGPHGKN_01853 568703.LGG_00980 2.69e-195 542.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,3F4N3@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N NAGPHGKN_01854 568703.LGG_00979 1.12e-162 456.0 COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,4HBUK@91061|Bacilli,3F3VV@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_01855 568703.LGG_00978 1.16e-234 650.0 COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,3F40D@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 NAGPHGKN_01856 568703.LGG_00977 7.67e-152 427.0 COG1309@1|root,COG1309@2|Bacteria,1V3R8@1239|Firmicutes,4HBEK@91061|Bacilli,3F6RQ@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_N NAGPHGKN_01857 568703.LGG_00976 0.0 1758.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HTQ4@91061|Bacilli,3FC0Z@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus pacL - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 NAGPHGKN_01859 568703.LGG_00974 2.37e-79 236.0 2CHWU@1|root,34CGV@2|Bacteria,1W494@1239|Firmicutes,4HZJS@91061|Bacilli,3F71N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01860 568703.LGG_00973 3.85e-116 334.0 2ER2X@1|root,33INI@2|Bacteria,1VNYA@1239|Firmicutes,4HSEZ@91061|Bacilli,3F717@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF5067) - - - - - - - - - - - - DUF5067 NAGPHGKN_01861 568703.LGG_00972 2.08e-267 731.0 COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli,3F3W1@33958|Lactobacillaceae 91061|Bacilli P ABC transporter potD - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSB619.SA_RS05395 SBP_bac_8 NAGPHGKN_01862 568703.LGG_00971 7.08e-187 520.0 COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli,3F3ZN@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease potC - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 NAGPHGKN_01863 568703.LGG_00970 2.13e-191 531.0 COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,4HAYS@91061|Bacilli,3F4CM@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease potB - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 NAGPHGKN_01864 568703.LGG_00969 9.49e-262 717.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,3F40H@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 - iSB619.SA_RS05380 ABC_tran,TOBE_2 NAGPHGKN_01865 568703.LGG_00968 4.84e-125 356.0 COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,4HHAY@91061|Bacilli,3FCDZ@33958|Lactobacillaceae 91061|Bacilli K Cupin domain - - - - - - - - - - - - Cupin_2,HTH_3 NAGPHGKN_01866 568703.LGG_00967 0.0 1322.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter yvgP GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger NAGPHGKN_01867 568703.LGG_00966 2.74e-211 584.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,3F40T@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C NAGPHGKN_01868 568703.LGG_00964 3.32e-191 529.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli,3F4GK@33958|Lactobacillaceae 91061|Bacilli L exodeoxyribonuclease III exoA GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos NAGPHGKN_01869 568703.LGG_00963 1.62e-128 365.0 COG0847@1|root,COG0847@2|Bacteria,1V57H@1239|Firmicutes,4HI1V@91061|Bacilli,3F42Z@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T NAGPHGKN_01870 568703.LGG_00962 2.46e-115 340.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,3F3KA@33958|Lactobacillaceae 91061|Bacilli CP ABC-2 family transporter protein ysdA - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 NAGPHGKN_01871 568703.LGG_00962 5.93e-136 395.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,3F3KA@33958|Lactobacillaceae 91061|Bacilli CP ABC-2 family transporter protein ysdA - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 NAGPHGKN_01872 568703.LGG_00961 2.96e-210 581.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,3F4J8@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 NAGPHGKN_01873 568703.LGG_00960 1.2e-106 307.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,3F3MR@33958|Lactobacillaceae 91061|Bacilli O Hydrolase, P-loop family ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE NAGPHGKN_01874 568703.LGG_00959 6.35e-230 633.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,3F3MW@33958|Lactobacillaceae 91061|Bacilli C phosphate acetyltransferase pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB NAGPHGKN_01875 568703.LGG_00958 4.68e-168 469.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,3F3W0@33958|Lactobacillaceae 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG NAGPHGKN_01876 568703.LGG_00957 1.98e-203 564.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,3F58Y@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase ycsE - - - - - - - - - - - Hydrolase_3 NAGPHGKN_01877 568703.LGG_00956 5.33e-119 340.0 COG4894@1|root,COG4894@2|Bacteria,1V8EY@1239|Firmicutes,4HMMS@91061|Bacilli,3F698@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - LOR NAGPHGKN_01878 568703.LGG_00955 7.94e-134 379.0 COG0454@1|root,COG0456@2|Bacteria,1V7GR@1239|Firmicutes,4HJ11@91061|Bacilli,3FB97@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - ko:K06977 - - - - ko00000 - - - Acetyltransf_1 NAGPHGKN_01879 568703.LGG_00954 2.11e-249 685.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HBKK@91061|Bacilli,3FC3J@33958|Lactobacillaceae 91061|Bacilli P ATPases associated with a variety of cellular activities malK - - ko:K10112,ko:K17240 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00599,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.38 - - ABC_tran,TOBE_2 NAGPHGKN_01880 568703.LGG_00953 1.21e-213 590.0 COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,4HCD0@91061|Bacilli,3F464@33958|Lactobacillaceae 91061|Bacilli P ABC-type sugar transport systems, permease components - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 NAGPHGKN_01881 568703.LGG_00952 1.1e-188 525.0 COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,4HBKE@91061|Bacilli,3FC8I@33958|Lactobacillaceae 91061|Bacilli G Binding-protein-dependent transport system inner membrane component malF - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 NAGPHGKN_01882 568703.LGG_00951 5.23e-313 853.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HEKH@91061|Bacilli,3F4P5@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 NAGPHGKN_01883 568703.LGG_00949 6.97e-304 828.0 COG0595@1|root,COG0595@2|Bacteria,1V0AV@1239|Firmicutes,4HEB0@91061|Bacilli,3FB9R@33958|Lactobacillaceae 91061|Bacilli S Metallo-beta-lactamase superfamily YSH1 - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,Lactamase_B_2 NAGPHGKN_01885 568703.LGG_00947 7.78e-66 200.0 29QAR@1|root,30B9X@2|Bacteria,1U7SN@1239|Firmicutes,4IHQ2@91061|Bacilli,3FA4A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01886 568703.LGG_00946 3.38e-149 421.0 COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,4HHB1@91061|Bacilli,3FCA1@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 5.4.2.6 ko:K01838 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 NAGPHGKN_01887 568703.LGG_00945 0.0 1527.0 COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,3F3PG@33958|Lactobacillaceae 91061|Bacilli G hydrolase, family 65, central catalytic mapA - 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 - R01555 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m NAGPHGKN_01888 568703.LGG_00944 0.0 1204.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,3F41N@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family nplT - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Alpha-amylase_N,Malt_amylase_C NAGPHGKN_01889 543734.LCABL_11400 9.03e-108 310.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,3F65B@33958|Lactobacillaceae 91061|Bacilli J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB NAGPHGKN_01890 568703.LGG_00942 0.0 1570.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,3F4EC@33958|Lactobacillaceae 91061|Bacilli J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 NAGPHGKN_01891 568703.LGG_00941 3.69e-177 493.0 COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4HBE6@91061|Bacilli,3F5XW@33958|Lactobacillaceae 91061|Bacilli S Serine aminopeptidase, S33 est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 NAGPHGKN_01892 568703.LGG_00940 2.92e-42 139.0 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli,3F7IQ@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG NAGPHGKN_01893 568703.LGG_00939 1.48e-78 234.0 29Q8Z@1|root,30B82@2|Bacteria,1U7Q4@1239|Firmicutes,4IHMF@91061|Bacilli,3FA07@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01894 568703.LGG_00938 8.04e-98 298.0 COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F3MU@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC NAGPHGKN_01895 568703.LGG_00938 5.63e-257 712.0 COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F3MU@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC NAGPHGKN_01896 568703.LGG_00937 5.53e-84 248.0 29QBC@1|root,30BAJ@2|Bacteria,1U7TN@1239|Firmicutes,4IHR4@91061|Bacilli,3FA5U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01897 568703.LGG_00936 5.04e-314 855.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,3F3JP@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N NAGPHGKN_01898 568703.LGG_00935 8.05e-180 500.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,3F494@33958|Lactobacillaceae 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM NAGPHGKN_01899 568703.LGG_00934 1.52e-282 772.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,3F3SC@33958|Lactobacillaceae 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK NAGPHGKN_01900 568703.LGG_00933 2.99e-247 678.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,3F3JS@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N NAGPHGKN_01901 568703.LGG_00932 2.73e-241 664.0 COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,3F53Y@33958|Lactobacillaceae 91061|Bacilli K Putative sugar-binding domain cggR - - ko:K05311 - - - - ko00000,ko03000 - - - Sugar-bind NAGPHGKN_01903 1423732.BALS01000004_gene1260 1.71e-131 374.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,3F3M0@33958|Lactobacillaceae 91061|Bacilli O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease NAGPHGKN_01904 568703.LGG_00930 6.45e-105 303.0 COG1846@1|root,COG1846@2|Bacteria,1V6G0@1239|Firmicutes,4HKQR@91061|Bacilli,3F74F@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein ohrR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K18906 - M00700,M00702,M00704,M00717 - - ko00000,ko00002,ko01504,ko03000 - - - MarR NAGPHGKN_01905 568703.LGG_00929 3.36e-220 608.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,3F4AB@33958|Lactobacillaceae 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N NAGPHGKN_01906 568703.LGG_00928 8.22e-246 675.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,3F4D5@33958|Lactobacillaceae 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 NAGPHGKN_01907 568703.LGG_00927 1.47e-213 589.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,3F4NY@33958|Lactobacillaceae 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 NAGPHGKN_01908 568703.LGG_00925 2.98e-110 318.0 COG3247@1|root,COG3247@2|Bacteria,1VJ0U@1239|Firmicutes,4HQJ0@91061|Bacilli,3FB5N@33958|Lactobacillaceae 91061|Bacilli S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 NAGPHGKN_01909 568703.LGG_00924 0.0 1897.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,3F4TZ@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran NAGPHGKN_01910 568703.LGG_00923 0.0 1300.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,3F3XM@33958|Lactobacillaceae 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB NAGPHGKN_01911 568703.LGG_00922 2.32e-152 428.0 COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,4HA8H@91061|Bacilli,3F4RZ@33958|Lactobacillaceae 91061|Bacilli S HD containing hydrolase-like enzyme yfbR - - ko:K07023 - - - - ko00000 - - - HD_2 NAGPHGKN_01912 543734.LCABL_10680 2.3e-178 527.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TRAS@1239|Firmicutes,4HC7R@91061|Bacilli,3F5WX@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD NAGPHGKN_01913 543734.LCABL_10680 6.82e-104 327.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TRAS@1239|Firmicutes,4HC7R@91061|Bacilli,3F5WX@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD NAGPHGKN_01914 1231336.L248_2708 1.21e-117 341.0 COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4HGIE@91061|Bacilli,3F6NW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_01915 543734.LCABL_10650 3.28e-143 414.0 COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,4HAPG@91061|Bacilli,3F619@33958|Lactobacillaceae 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA NAGPHGKN_01916 543734.LCABL_10640 2.18e-109 319.0 COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,4HDD2@91061|Bacilli,3F6EC@33958|Lactobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C NAGPHGKN_01917 568703.LGG_00921 0.0 1132.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,3F457@33958|Lactobacillaceae 91061|Bacilli G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV NAGPHGKN_01918 568703.LGG_00920 8.36e-230 632.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,3F411@33958|Lactobacillaceae 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 NAGPHGKN_01919 568703.LGG_00919 1.8e-249 685.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,3F4C8@33958|Lactobacillaceae 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N NAGPHGKN_01920 568703.LGG_00918 2e-201 557.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,3F42N@33958|Lactobacillaceae 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT NAGPHGKN_01921 568703.LGG_00917 5.82e-223 615.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,3F3Z3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N NAGPHGKN_01922 568703.LGG_00916 2.28e-61 189.0 COG1950@1|root,COG1950@2|Bacteria,1VF4I@1239|Firmicutes,4HNXP@91061|Bacilli,3F7IN@33958|Lactobacillaceae 91061|Bacilli S Mycobacterial 4 TMS phage holin, superfamily IV yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 NAGPHGKN_01923 568703.LGG_00915 7.01e-49 156.0 2A2TA@1|root,30R6T@2|Bacteria,1U7RM@1239|Firmicutes,4IHNY@91061|Bacilli,3FA2M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01924 568703.LGG_00914 0.0 877.0 COG2433@1|root,COG3595@1|root,COG2433@2|Bacteria,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,3F5QQ@33958|Lactobacillaceae 91061|Bacilli S Putative adhesin yvlB - - - - - - - - - - - DUF4097 NAGPHGKN_01925 568703.LGG_00911 1.33e-156 439.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,3F46W@33958|Lactobacillaceae 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU NAGPHGKN_01926 568703.LGG_00910 1.75e-180 502.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB1 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran NAGPHGKN_01927 568703.LGG_00909 1.83e-191 531.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB2 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran NAGPHGKN_01928 568703.LGG_00908 3.55e-200 555.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,3F412@33958|Lactobacillaceae 91061|Bacilli P Phosphate transport system permease protein PstA pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 NAGPHGKN_01929 568703.LGG_00907 1.56e-205 570.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,3F3NI@33958|Lactobacillaceae 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 NAGPHGKN_01930 568703.LGG_00906 5.25e-199 552.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 NAGPHGKN_01931 568703.LGG_00905 0.0 1056.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,3F3W2@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like NAGPHGKN_01932 568703.LGG_00904 9.79e-168 468.0 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,3FC91@33958|Lactobacillaceae 91061|Bacilli K response regulator phoP - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C NAGPHGKN_01933 568703.LGG_00903 7.95e-251 689.0 COG0265@1|root,COG0265@2|Bacteria,1TSBA@1239|Firmicutes,4HA05@91061|Bacilli,3F4TP@33958|Lactobacillaceae 91061|Bacilli O Domain present in PSD-95, Dlg, and ZO-1/2. minJ - - - - - - - - - - - PDZ_2 NAGPHGKN_01934 568703.LGG_00902 4.17e-204 565.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,3F4MK@33958|Lactobacillaceae 91061|Bacilli D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX NAGPHGKN_01935 568703.LGG_00901 2.59e-160 449.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,3F4JC@33958|Lactobacillaceae 91061|Bacilli D ABC transporter ftsE GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran NAGPHGKN_01936 568703.LGG_00900 6.43e-238 654.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,3F3SN@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 NAGPHGKN_01937 568703.LGG_00899 0.0 1539.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,3F4DH@33958|Lactobacillaceae 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SecA_DEAD,SecA_PP_bind,SecA_SW NAGPHGKN_01938 568703.LGG_00896 7.96e-127 361.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,3F40M@33958|Lactobacillaceae 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE NAGPHGKN_01939 568703.LGG_00895 1.8e-117 338.0 COG1040@1|root,COG1040@2|Bacteria,1V73S@1239|Firmicutes,4HJ6R@91061|Bacilli,3F714@33958|Lactobacillaceae 91061|Bacilli S Competence protein comFC - - ko:K02242 - M00429 - - ko00000,ko00002,ko02044 - - - Pribosyltran NAGPHGKN_01940 568703.LGG_00894 3.04e-297 811.0 COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli,3F3TQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K02240 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1 - - DEAD,Helicase_C,ResIII NAGPHGKN_01941 568703.LGG_00893 2.6e-150 423.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli,3F3SQ@33958|Lactobacillaceae 91061|Bacilli S YigZ family yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 NAGPHGKN_01942 568703.LGG_00892 0.0 880.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,3F3WX@33958|Lactobacillaceae 91061|Bacilli S Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 NAGPHGKN_01943 568703.LGG_00889 6.68e-240 660.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA NAGPHGKN_01944 568703.LGG_00888 3.23e-288 788.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,3F4I4@33958|Lactobacillaceae 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth NAGPHGKN_01945 568703.LGG_00887 7.88e-135 382.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,3F4BI@33958|Lactobacillaceae 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf NAGPHGKN_01946 568703.LGG_00886 1.8e-167 474.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,3F3SM@33958|Lactobacillaceae 91061|Bacilli S Helix-turn-helix domain ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 NAGPHGKN_01947 568703.LGG_00885 1.43e-164 461.0 COG1028@1|root,COG1028@2|Bacteria,1V0YW@1239|Firmicutes,4ISGK@91061|Bacilli,3FBEA@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 NAGPHGKN_01948 568703.LGG_00884 3.94e-309 842.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,3F4MU@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C NAGPHGKN_01949 568703.LGG_00883 7.4e-293 800.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,3F3SA@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 inactive domain protein ymfF - - - - - - - - - - - Peptidase_M16_C NAGPHGKN_01950 568703.LGG_00882 0.0 1383.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,3F3JZ@33958|Lactobacillaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma NAGPHGKN_01952 1423732.BALS01000003_gene941 1.27e-76 229.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,3F6WZ@33958|Lactobacillaceae 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA NAGPHGKN_01953 568703.LGG_01610 4.46e-181 504.0 COG0861@1|root,COG0861@2|Bacteria,1UVIJ@1239|Firmicutes,4HEKW@91061|Bacilli,3F3WS@33958|Lactobacillaceae 91061|Bacilli P membrane yceF - - ko:K05794 - - - - ko00000 - - - TerC NAGPHGKN_01954 568703.LGG_01609 3.43e-206 571.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,3F3NX@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N NAGPHGKN_01955 568703.LGG_01608 2.57e-224 618.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,3F3TG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase NAGPHGKN_01956 568703.LGG_01607 2.08e-286 781.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,3F4BA@33958|Lactobacillaceae 91061|Bacilli H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM NAGPHGKN_01957 568703.LGG_01606 2.27e-246 677.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,3F3ST@33958|Lactobacillaceae 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg NAGPHGKN_01958 568703.LGG_01605 2.41e-127 363.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,3F4DY@33958|Lactobacillaceae 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE NAGPHGKN_01959 568703.LGG_01604 0.0 1142.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,3F48C@33958|Lactobacillaceae 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 NAGPHGKN_01960 568703.LGG_01603 6.01e-268 734.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,3F490@33958|Lactobacillaceae 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG NAGPHGKN_01961 568703.LGG_01602 0.0 1184.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,3F3Z1@33958|Lactobacillaceae 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C NAGPHGKN_01962 568703.LGG_01601 4.01e-44 143.0 2AI13@1|root,318EQ@2|Bacteria,1U7VD@1239|Firmicutes,4IHST@91061|Bacilli,3FA82@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01963 568703.LGG_01600 4.13e-109 314.0 COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli,3F9AG@33958|Lactobacillaceae 91061|Bacilli S ASCH - - - - - - - - - - - - ASCH NAGPHGKN_01964 568703.LGG_01599 2.01e-81 241.0 29PHG@1|root,30AFM@2|Bacteria,1U6KN@1239|Firmicutes,4IGDE@91061|Bacilli,3F83U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01965 568703.LGG_01598 0.0 1461.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,3F42C@33958|Lactobacillaceae 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C NAGPHGKN_01966 1423732.BALS01000003_gene959 4.87e-123 350.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli,3F4DB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran NAGPHGKN_01967 568703.LGG_01596 2.18e-117 335.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HHVB@91061|Bacilli,3F5H1@33958|Lactobacillaceae 91061|Bacilli S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit NAGPHGKN_01968 568703.LGG_01595 8.85e-72 215.0 2ED3T@1|root,3370N@2|Bacteria,1VIJK@1239|Firmicutes,4HPGM@91061|Bacilli,3F765@33958|Lactobacillaceae 91061|Bacilli S Staphylococcal protein of unknown function (DUF960) XK27_08430 - - - - - - - - - - - DUF960 NAGPHGKN_01969 568703.LGG_01594 5.46e-189 525.0 COG3741@1|root,COG3741@2|Bacteria,1V6B3@1239|Firmicutes,4HQ4E@91061|Bacilli,3F6V6@33958|Lactobacillaceae 91061|Bacilli E N-formylglutamate amidohydrolase hutG - 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - FGase NAGPHGKN_01970 568703.LGG_01593 1.07e-238 656.0 29Q4I@1|root,30B38@2|Bacteria,1U7GD@1239|Firmicutes,4IHCJ@91061|Bacilli,3F9M4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01971 568703.LGG_01592 1.75e-274 921.0 2DQAU@1|root,335PW@2|Bacteria,1VR35@1239|Firmicutes,4HUUM@91061|Bacilli,3F7WX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01972 568703.LGG_01591 0.0 1298.0 29Q3U@1|root,30B2I@2|Bacteria,1U7FA@1239|Firmicutes,4IHBA@91061|Bacilli,3F9IU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01974 568703.LGG_01589 0.0 1071.0 COG2340@1|root,COG4932@1|root,COG2340@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - 2.4.1.9,3.4.24.40 ko:K01406,ko:K20811 ko00500,ko01503,map00500,map01503 - R04194 RC00077,RC00247 ko00000,ko00001,ko01000,ko01002 - GH68 - CAP,CW_binding_2,SLH NAGPHGKN_01976 568703.LGG_01587 0.0 1033.0 COG0438@1|root,COG0438@2|Bacteria,1UY71@1239|Firmicutes,4HFBM@91061|Bacilli,3FC1Q@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Glycos_transf_1 NAGPHGKN_01977 568703.LGG_01586 0.0 1007.0 COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli,3F4P6@33958|Lactobacillaceae 91061|Bacilli M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon tagE GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Asp1,Glyco_trans_A_1,Glycos_transf_1 NAGPHGKN_01978 568703.LGG_01582 5.29e-238 654.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,3F4EV@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase mocA - - - - - - - - - - - GFO_IDH_MocA NAGPHGKN_01979 568703.LGG_01580 3.21e-117 337.0 COG1309@1|root,COG1309@2|Bacteria,1W6HU@1239|Firmicutes,4HY6F@91061|Bacilli,3F6V3@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N NAGPHGKN_01980 568703.LGG_01579 1.6e-145 409.0 COG2249@1|root,COG2249@2|Bacteria,1VB36@1239|Firmicutes,4HW64@91061|Bacilli,3F66F@33958|Lactobacillaceae 91061|Bacilli S Flavodoxin-like fold - - - - - - - - - - - - Flavodoxin_2 NAGPHGKN_01982 568703.LGG_01578 1.05e-79 238.0 29PAD@1|root,30A8I@2|Bacteria,1U6BX@1239|Firmicutes,4IG3I@91061|Bacilli,3F7JN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01983 568703.LGG_01577 3.45e-37 124.0 29QDN@1|root,30BCY@2|Bacteria,1U7XK@1239|Firmicutes,4IHUZ@91061|Bacilli,3FAAQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01984 568703.LGG_01576 9.77e-80 237.0 COG5294@1|root,COG5294@2|Bacteria,1W0J9@1239|Firmicutes,4HYK1@91061|Bacilli,3F8AZ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 NAGPHGKN_01985 568703.LGG_01575 1.1e-50 160.0 29QBB@1|root,30BAI@2|Bacteria,1U7TK@1239|Firmicutes,4IHR2@91061|Bacilli,3FA5R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01986 568703.LGG_01574 2.26e-143 404.0 COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HJ10@91061|Bacilli,3FC7N@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA glycosylase MPG family - GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco NAGPHGKN_01987 568703.LGG_01573 2.02e-112 323.0 2E0MY@1|root,32W75@2|Bacteria,1VFZQ@1239|Firmicutes,4HKWR@91061|Bacilli,3F6FP@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3013) XK27_03960 - - - - - - - - - - - DUF3013 NAGPHGKN_01988 568703.LGG_01572 5.37e-221 610.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,3F47Z@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA NAGPHGKN_01989 568703.LGG_01571 7.38e-167 467.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,3F64Z@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA NAGPHGKN_01990 568703.LGG_01570 1.7e-70 212.0 2DKTI@1|root,30ARB@2|Bacteria,1U70F@1239|Firmicutes,4IGUR@91061|Bacilli,3F8T9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01991 568703.LGG_01569 0.0 1466.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS NAGPHGKN_01992 568703.LGG_01568 2.17e-97 283.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,3F6GK@33958|Lactobacillaceae 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase NAGPHGKN_01993 568703.LGG_01567 2.95e-147 414.0 COG0546@1|root,COG0546@2|Bacteria,1V3DR@1239|Firmicutes,4HGMU@91061|Bacilli,3F741@33958|Lactobacillaceae 91061|Bacilli J HAD-hyrolase-like - - - - - - - - - - - - HAD_2 NAGPHGKN_01994 568703.LGG_01566 0.0 865.0 COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,3F4F4@33958|Lactobacillaceae 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3 NAGPHGKN_01995 568703.LGG_01565 1.72e-103 299.0 COG0537@1|root,COG0537@2|Bacteria,1V5XZ@1239|Firmicutes,4HHN5@91061|Bacilli,3FCAY@33958|Lactobacillaceae 91061|Bacilli FG adenosine 5'-monophosphoramidase activity - - - - - - - - - - - - HIT NAGPHGKN_01996 568703.LGG_01564 1.95e-168 473.0 COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,4HFS1@91061|Bacilli,3F52V@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - - - - - - - - - - ABC_tran NAGPHGKN_01997 568703.LGG_01563 7.14e-61 200.0 2DV5N@1|root,33U6G@2|Bacteria,1VUTX@1239|Firmicutes,4HVQT@91061|Bacilli,3FBQP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01998 568703.LGG_01563 7.1e-247 686.0 2DV5N@1|root,33U6G@2|Bacteria,1VUTX@1239|Firmicutes,4HVQT@91061|Bacilli,3FBQP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_01999 568703.LGG_01562 1.8e-308 840.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,3F3M3@33958|Lactobacillaceae 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His NAGPHGKN_02000 568703.LGG_01561 0.0 1209.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,3F4PE@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon NAGPHGKN_02001 568703.LGG_01560 1.26e-105 304.0 COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,4HGWN@91061|Bacilli,3F6H4@33958|Lactobacillaceae 91061|Bacilli O peptide methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR NAGPHGKN_02002 568703.LGG_01559 7.61e-217 598.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,3F3PH@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 yitT - - - - - - - - - - - DUF2179,YitT_membrane NAGPHGKN_02003 568703.LGG_01558 6.26e-215 593.0 COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,4HB4F@91061|Bacilli,3F42I@33958|Lactobacillaceae 91061|Bacilli L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 NAGPHGKN_02004 568703.LGG_01557 4.18e-199 551.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,3F3WK@33958|Lactobacillaceae 91061|Bacilli F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase NAGPHGKN_02005 568703.LGG_01556 5.66e-29 103.0 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli,3F81Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 NAGPHGKN_02006 568703.LGG_01555 1.47e-90 266.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,3F6I0@33958|Lactobacillaceae 91061|Bacilli S YqeY-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY NAGPHGKN_02007 568703.LGG_01554 6.59e-229 631.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,3F4E7@33958|Lactobacillaceae 91061|Bacilli T phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH NAGPHGKN_02008 568703.LGG_01553 5.09e-107 308.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,3F516@33958|Lactobacillaceae 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 NAGPHGKN_02009 568703.LGG_01552 4.25e-85 251.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,3F7DC@33958|Lactobacillaceae 91061|Bacilli M Diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSB619.SA_RS07900 DAGK_prokar NAGPHGKN_02010 568703.LGG_01551 8.35e-84 248.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli,3F7RM@33958|Lactobacillaceae 91061|Bacilli F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 NAGPHGKN_02011 568703.LGG_01550 5.57e-216 596.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,3F3WQ@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 NAGPHGKN_02012 568703.LGG_01549 4.96e-188 522.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,3F56P@33958|Lactobacillaceae 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N NAGPHGKN_02013 568703.LGG_01548 7.35e-70 210.0 2C8G2@1|root,348DR@2|Bacteria,1VZDC@1239|Firmicutes,4HZ47@91061|Bacilli,3F740@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02014 568703.LGG_01547 1.08e-155 438.0 COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,4HK33@91061|Bacilli,3F7PH@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_02016 568703.LGG_01545 1.77e-44 148.0 COG1670@1|root,COG1670@2|Bacteria,1V4ZB@1239|Firmicutes,4HHG0@91061|Bacilli,3FCAZ@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 NAGPHGKN_02017 568703.LGG_00020 5.77e-244 670.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HADR@91061|Bacilli,3F3YG@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve NAGPHGKN_02018 568703.LGG_01545 3.51e-67 206.0 COG1670@1|root,COG1670@2|Bacteria,1V4ZB@1239|Firmicutes,4HHG0@91061|Bacilli,3FCAZ@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 NAGPHGKN_02019 568703.LGG_01514 1.96e-224 617.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,3F3T8@33958|Lactobacillaceae 91061|Bacilli J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e NAGPHGKN_02020 568703.LGG_01513 0.0 1305.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,3F4G8@33958|Lactobacillaceae 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f NAGPHGKN_02021 568703.LGG_01512 0.0 1154.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,3F3N1@33958|Lactobacillaceae 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 NAGPHGKN_02022 568703.LGG_01511 1.21e-257 711.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,3F4CF@33958|Lactobacillaceae 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 NAGPHGKN_02023 568703.LGG_01510 1.39e-130 373.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,3F4GT@33958|Lactobacillaceae 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK NAGPHGKN_02024 568703.LGG_01509 1.83e-187 521.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,3F3ZD@33958|Lactobacillaceae 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 NAGPHGKN_02025 568703.LGG_01508 0.0 1061.0 COG1132@1|root,COG1132@2|Bacteria,1TRCZ@1239|Firmicutes,4HCDT@91061|Bacilli 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran NAGPHGKN_02026 568703.LGG_01507 0.0 941.0 COG1132@1|root,COG1132@2|Bacteria 2|Bacteria V (ABC) transporter - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NAGPHGKN_02027 568703.LGG_01506 1.05e-35 121.0 COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli,3F83T@33958|Lactobacillaceae 91061|Bacilli G Belongs to the 4-oxalocrotonate tautomerase family dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase NAGPHGKN_02028 568703.LGG_01505 1.15e-79 236.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,3F7D5@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein yitW - - - - - - - - - - - DUF1858,FeS_assembly_P NAGPHGKN_02029 568703.LGG_01504 5.06e-181 503.0 2E39Q@1|root,32Y99@2|Bacteria,1VQQ8@1239|Firmicutes,4HRY1@91061|Bacilli,3F4UX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02030 568703.LGG_01502 1.54e-222 614.0 2EPHD@1|root,33H40@2|Bacteria,1VNCY@1239|Firmicutes,4HYY7@91061|Bacilli,3F495@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - MacB_PCD NAGPHGKN_02031 568703.LGG_01501 0.0 900.0 COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli,3F492@33958|Lactobacillaceae 91061|Bacilli J NOL1 NOP2 sun family protein rsmF - - - - - - - - - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI NAGPHGKN_02032 568703.LGG_01500 7.36e-250 685.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,3F3UY@33958|Lactobacillaceae 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh NAGPHGKN_02033 568703.LGG_01499 3.66e-229 632.0 COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli,3F4B5@33958|Lactobacillaceae 91061|Bacilli I diphosphomevalonate decarboxylase mvaD - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N NAGPHGKN_02034 568703.LGG_01498 4.19e-212 587.0 COG1577@1|root,COG1577@2|Bacteria,1TT5C@1239|Firmicutes,4HAQQ@91061|Bacilli,3F3TW@33958|Lactobacillaceae 91061|Bacilli I mevalonate kinase mvk - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N NAGPHGKN_02035 568703.LGG_01497 0.0 1338.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,3F3RS@33958|Lactobacillaceae 91061|Bacilli L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C NAGPHGKN_02036 568703.LGG_01497 0.0 946.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,3F3RS@33958|Lactobacillaceae 91061|Bacilli L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C NAGPHGKN_02037 568703.LGG_01496 0.0 2358.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,3F3Z0@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C NAGPHGKN_02038 568703.LGG_01495 0.0 1794.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,3F4KA@33958|Lactobacillaceae 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII NAGPHGKN_02039 568703.LGG_01493 8.92e-111 318.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,3F4MM@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria ypmB - - - - - - - - - - - PepSY NAGPHGKN_02040 568703.LGG_01492 3.43e-281 768.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 NAGPHGKN_02041 568703.LGG_01491 0.0 893.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,3F4EK@33958|Lactobacillaceae 91061|Bacilli J Asparaginyl-tRNA synthetase asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon NAGPHGKN_02042 568703.LGG_01490 9.49e-143 403.0 COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,3F4FF@33958|Lactobacillaceae 91061|Bacilli L DnaD domain protein dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 NAGPHGKN_02043 568703.LGG_01489 1.9e-147 416.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,3F42U@33958|Lactobacillaceae 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD NAGPHGKN_02044 568703.LGG_01488 7.79e-112 320.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HCDG@91061|Bacilli,3F6BF@33958|Lactobacillaceae 91061|Bacilli F ComE operon protein 2 comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 NAGPHGKN_02045 568703.LGG_01487 0.0 1377.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F424@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein 1A ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 NAGPHGKN_02046 568703.LGG_01486 4.21e-156 437.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,3F4DG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU NAGPHGKN_02047 568703.LGG_01485 1.54e-136 386.0 COG4474@1|root,COG4474@2|Bacteria,1V6SM@1239|Firmicutes,4HJGM@91061|Bacilli,3F4MR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0398 family ypsA - - - - - - - - - - - DUF1273 NAGPHGKN_02048 568703.LGG_01484 5.37e-88 258.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli,3F6VZ@33958|Lactobacillaceae 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA NAGPHGKN_02050 568703.LGG_01482 5.02e-277 757.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,3F3NZ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 NAGPHGKN_02051 568703.LGG_01481 2.57e-222 613.0 COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4HAW5@91061|Bacilli,3F4DF@33958|Lactobacillaceae 91061|Bacilli EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C NAGPHGKN_02052 568703.LGG_01480 7.29e-46 147.0 2CDEF@1|root,30AS2@2|Bacteria,1U71A@1239|Firmicutes,4IGVR@91061|Bacilli,3F8UP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02053 568703.LGG_01479 4.08e-248 680.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,3F4UZ@33958|Lactobacillaceae 91061|Bacilli H Lipoate-protein ligase lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C NAGPHGKN_02054 568703.LGG_01478 0.0 1280.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F4CX@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N NAGPHGKN_02055 568703.LGG_01476 2.53e-210 581.0 COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HAZB@91061|Bacilli,3F3VP@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator lysR - - - - - - - - - - - HTH_1,LysR_substrate NAGPHGKN_02057 568703.LGG_01475 2.95e-240 659.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,3F3P1@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm NAGPHGKN_02058 568703.LGG_01474 0.0 1443.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,3F3XG@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN NAGPHGKN_02059 568703.LGG_01473 1.76e-51 162.0 COG0695@1|root,COG0695@2|Bacteria,1VEFX@1239|Firmicutes,4HNUX@91061|Bacilli,3F874@33958|Lactobacillaceae 91061|Bacilli O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin NAGPHGKN_02060 568703.LGG_01472 0.0 937.0 2C9BC@1|root,2ZI2Q@2|Bacteria,1TVHZ@1239|Firmicutes,4I07N@91061|Bacilli,3F96P@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - Mga NAGPHGKN_02061 568703.LGG_00891 4.86e-05 43.9 2BT3F@1|root,32N80@2|Bacteria,1U8CV@1239|Firmicutes,4IIAU@91061|Bacilli,3FAUG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02062 568703.LGG_01471 5.46e-72 216.0 29PM1@1|root,30AJ7@2|Bacteria,1U6RT@1239|Firmicutes,4IGJ9@91061|Bacilli,3F8DQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02063 568703.LGG_01469 0.0 968.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N NAGPHGKN_02064 568703.LGG_01468 1.72e-142 402.0 COG3560@1|root,COG3560@2|Bacteria,1V1CR@1239|Firmicutes,4HD6W@91061|Bacilli,3F576@33958|Lactobacillaceae 91061|Bacilli S Nitroreductase family XK27_02070 - - ko:K07078 - - - - ko00000 - - - Nitroreductase NAGPHGKN_02065 568703.LGG_01467 5.59e-90 263.0 COG0328@1|root,COG0328@2|Bacteria,1VH2B@1239|Firmicutes,4HIY9@91061|Bacilli,3F7JC@33958|Lactobacillaceae 91061|Bacilli L Ribonuclease HI rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H,RVT_3 NAGPHGKN_02066 568703.LGG_01466 5.76e-84 248.0 2BF1V@1|root,328TS@2|Bacteria,1UUT0@1239|Firmicutes,4IHGJ@91061|Bacilli,3F9TN@33958|Lactobacillaceae 91061|Bacilli S Family of unknown function (DUF5322) - - - - - - - - - - - - DUF5322 NAGPHGKN_02067 568703.LGG_01465 0.0 1101.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,3F3U6@33958|Lactobacillaceae 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS NAGPHGKN_02068 568703.LGG_01464 1.99e-106 308.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,3F66R@33958|Lactobacillaceae 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 NAGPHGKN_02069 568703.LGG_01463 1.74e-222 613.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,3F3P6@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 NAGPHGKN_02070 568703.LGG_01461 3.67e-126 359.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,3F4SR@33958|Lactobacillaceae 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran NAGPHGKN_02071 568703.LGG_01460 2.33e-299 818.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,3F3UJ@33958|Lactobacillaceae 91061|Bacilli F Permease pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease NAGPHGKN_02072 568703.LGG_01459 5.88e-229 630.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,3F4BQ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N NAGPHGKN_02073 568703.LGG_01458 1.12e-305 833.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,3F3S3@33958|Lactobacillaceae 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 NAGPHGKN_02074 568703.LGG_01457 5.32e-267 730.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,3F43R@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase NAGPHGKN_02075 568703.LGG_01456 1.17e-248 711.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS NAGPHGKN_02076 568703.LGG_01456 0.0 1326.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS NAGPHGKN_02077 568703.LGG_01455 3.8e-193 537.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,3F4PJ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh NAGPHGKN_02078 568703.LGG_01454 6.86e-123 353.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,3F47Y@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase NAGPHGKN_02079 568703.LGG_01453 3.69e-143 404.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,3F487@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran NAGPHGKN_02080 568703.LGG_01452 3.31e-246 679.0 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HAK5@91061|Bacilli,3FCB4@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase system, EIIC pfoS/R - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 NAGPHGKN_02081 568703.LGG_01451 1.43e-67 204.0 COG1694@1|root,COG1694@2|Bacteria,1VJNA@1239|Firmicutes,4I1AJ@91061|Bacilli,3F7BG@33958|Lactobacillaceae 91061|Bacilli S MazG-like family - - - - - - - - - - - - MazG-like NAGPHGKN_02082 568703.LGG_01450 0.0 1111.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,3F3PS@33958|Lactobacillaceae 91061|Bacilli K Fibronectin-binding protein FbpA - - - - - - - - - - - DUF814,FbpA NAGPHGKN_02084 568703.LGG_01448 3.08e-207 573.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,3F40W@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family - - - - - - - - - - - - DegV NAGPHGKN_02085 568703.LGG_01447 3.8e-130 369.0 COG0494@1|root,COG0494@2|Bacteria,1VXC7@1239|Firmicutes,4HX58@91061|Bacilli,3F45R@33958|Lactobacillaceae 91061|Bacilli L Belongs to the Nudix hydrolase family - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX NAGPHGKN_02086 568703.LGG_01446 1.99e-260 714.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,3F97T@33958|Lactobacillaceae 91061|Bacilli E Cys/Met metabolism PLP-dependent enzyme hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 NAGPHGKN_02087 568703.LGG_01445 1.1e-277 759.0 COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli,3F4W1@33958|Lactobacillaceae 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His NAGPHGKN_02088 568703.LGG_01444 2.28e-54 174.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli,3F4WT@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His NAGPHGKN_02089 568703.LGG_01444 2.13e-58 185.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli,3F4WT@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His NAGPHGKN_02090 568703.LGG_01443 3.62e-287 786.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,3F40P@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU34910 Histidinol_dh NAGPHGKN_02091 568703.LGG_01441 9.96e-135 382.0 COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli,3F4TQ@33958|Lactobacillaceae 91061|Bacilli E imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14130 IGPD NAGPHGKN_02092 568703.LGG_01440 1.15e-144 408.0 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HHSP@91061|Bacilli,3FBCG@33958|Lactobacillaceae 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase NAGPHGKN_02093 568703.LGG_01439 2.97e-108 316.0 COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli,3F5YT@33958|Lactobacillaceae 91061|Bacilli E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth NAGPHGKN_02094 568703.LGG_01439 9.22e-47 155.0 COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli,3F5YT@33958|Lactobacillaceae 91061|Bacilli E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth NAGPHGKN_02095 568703.LGG_01438 4.26e-171 478.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli,3F3XV@33958|Lactobacillaceae 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth NAGPHGKN_02096 568703.LGG_01437 4.81e-76 226.0 COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,3F73W@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH NAGPHGKN_02097 568703.LGG_01436 5.01e-69 209.0 COG0140@1|root,COG0140@2|Bacteria,1VB6S@1239|Firmicutes,4HKDY@91061|Bacilli,3F7V5@33958|Lactobacillaceae 91061|Bacilli E phosphoribosyl-ATP diphosphatase activity hisE - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH NAGPHGKN_02098 568703.LGG_01435 4.53e-263 721.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,3F466@33958|Lactobacillaceae 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 NAGPHGKN_02099 568703.LGG_01434 3.82e-187 520.0 COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,3F585@33958|Lactobacillaceae 91061|Bacilli Q Fumarylacetoacetate (FAA) hydrolase family yisK - 3.7.1.5,4.1.1.68 ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 M00533 R01085,R04134,R04380 RC00326,RC00446,RC01085,RC02669 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase NAGPHGKN_02100 568703.LGG_01433 1.76e-145 410.0 COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HYXD@91061|Bacilli,3F9QI@33958|Lactobacillaceae 91061|Bacilli C Nitroreductase family - - - - - - - - - - - - Nitroreductase NAGPHGKN_02101 568703.LGG_01432 1.22e-93 273.0 COG0454@1|root,COG0456@2|Bacteria,1UVU0@1239|Firmicutes,4IG71@91061|Bacilli,3F7S8@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 NAGPHGKN_02102 568703.LGG_01431 7.37e-90 263.0 COG0454@1|root,COG0456@2|Bacteria,1UI3A@1239|Firmicutes,4ISBV@91061|Bacilli,3F83Y@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 NAGPHGKN_02103 568703.LGG_01430 2.13e-277 760.0 COG0477@1|root,COG0477@2|Bacteria,1UHRM@1239|Firmicutes,4ISTP@91061|Bacilli,3FBXB@33958|Lactobacillaceae 91061|Bacilli EGP Transmembrane secretion effector - - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1 NAGPHGKN_02104 568703.LGG_01429 1.24e-164 460.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HIBI@91061|Bacilli,3FC95@33958|Lactobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C NAGPHGKN_02105 568703.LGG_01428 5.58e-221 610.0 COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,4ITPK@91061|Bacilli,3FBXK@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c NAGPHGKN_02106 568703.LGG_01427 5.18e-174 486.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3F3MG@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein XK27_05695 - - ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 - - ABC_tran NAGPHGKN_02107 568703.LGG_01426 2.75e-244 685.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli,3FBRY@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family XK27_05700 - - ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 - - FtsX NAGPHGKN_02108 568703.LGG_01426 1.64e-174 503.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli,3FBRY@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family XK27_05700 - - ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 - - FtsX NAGPHGKN_02109 568703.LGG_01425 9.88e-55 180.0 COG4974@1|root,COG4974@2|Bacteria,1URNQ@1239|Firmicutes,4HEPI@91061|Bacilli,3FBHV@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family xerS - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase NAGPHGKN_02110 568703.LGG_01425 2.88e-197 550.0 COG4974@1|root,COG4974@2|Bacteria,1URNQ@1239|Firmicutes,4HEPI@91061|Bacilli,3FBHV@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family xerS - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase NAGPHGKN_02111 568703.LGG_01424 1.13e-220 608.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,3F3PJ@33958|Lactobacillaceae 91061|Bacilli C inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 NAGPHGKN_02112 568703.LGG_01423 1.15e-235 647.0 COG0583@1|root,COG0583@2|Bacteria,1UYRT@1239|Firmicutes,4IQQ1@91061|Bacilli,3FBIB@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate NAGPHGKN_02113 568703.LGG_01422 3.64e-217 597.0 COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,4HACV@91061|Bacilli,3F472@33958|Lactobacillaceae 91061|Bacilli C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM NAGPHGKN_02114 568703.LGG_01421 0.0 1531.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,4H9RD@91061|Bacilli,3F53K@33958|Lactobacillaceae 91061|Bacilli C Pyruvate formate lyase-like pflB GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like NAGPHGKN_02115 568703.LGG_01420 0.0 1575.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,3F3MJ@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV NAGPHGKN_02116 568703.LGG_01419 0.0 1321.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,3F430@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim NAGPHGKN_02117 568703.LGG_01418 5.92e-142 401.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,3F543@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf NAGPHGKN_02118 568703.LGG_01417 4.61e-220 605.0 COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,4HA4J@91061|Bacilli,3F3KT@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase lacX - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim NAGPHGKN_02119 568703.LGG_01416 0.0 889.0 COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,3F3WB@33958|Lactobacillaceae 91061|Bacilli O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small NAGPHGKN_02120 568703.LGG_01414 8.41e-119 340.0 COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,3F4HS@33958|Lactobacillaceae 91061|Bacilli O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome NAGPHGKN_02121 568703.LGG_01413 3.34e-214 591.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,3F44K@33958|Lactobacillaceae 91061|Bacilli D Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase NAGPHGKN_02122 568703.LGG_01412 3.4e-315 858.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,3F3WW@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA NAGPHGKN_02123 568703.LGG_01411 0.0 1347.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,3F3VS@33958|Lactobacillaceae 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom NAGPHGKN_02124 568703.LGG_01410 4.65e-189 525.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,3F41U@33958|Lactobacillaceae 91061|Bacilli LU DNA protecting protein DprA dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A NAGPHGKN_02125 568703.LGG_01409 1.61e-175 489.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,3F3JC@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII NAGPHGKN_02126 568703.LGG_01408 7.5e-202 559.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,3F3MI@33958|Lactobacillaceae 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 NAGPHGKN_02127 568703.LGG_01407 3.27e-167 467.0 28K10@1|root,2Z9QW@2|Bacteria,1VU2U@1239|Firmicutes,4HVDF@91061|Bacilli,3F4AC@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4918) - - - - - - - - - - - - DUF4918 NAGPHGKN_02128 592029.DDD_0723 3.12e-08 65.1 28IAD@1|root,2Z8CZ@2|Bacteria,4NIKV@976|Bacteroidetes,1I7BB@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - NAGPHGKN_02130 1408311.JNJM01000037_gene2232 6.14e-75 279.0 2C0IE@1|root,2Z7YA@2|Bacteria,1U1MA@1239|Firmicutes,24BCE@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score - - - - - - - - - - - - - NAGPHGKN_02131 568703.LGG_01405 0.0 899.0 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,3F3SS@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 NAGPHGKN_02132 568703.LGG_01404 2.52e-55 172.0 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli,3F7ZP@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like NAGPHGKN_02133 568703.LGG_01403 1.41e-125 357.0 COG0225@1|root,COG0225@2|Bacteria,1V1MJ@1239|Firmicutes,4HG4U@91061|Bacilli,3FBG0@33958|Lactobacillaceae 91061|Bacilli C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR NAGPHGKN_02134 568703.LGG_01402 5.89e-145 409.0 COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli,3F5K5@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2140) ypmS - - - - - - - - - - - DUF2140 NAGPHGKN_02135 568703.LGG_01401 3.87e-202 559.0 COG2755@1|root,COG2755@2|Bacteria,1V1HR@1239|Firmicutes,4HDXS@91061|Bacilli,3F4N0@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase XK27_03630 - - - - - - - - - - - Lipase_GDSL_2 NAGPHGKN_02136 568703.LGG_01400 2.79e-190 529.0 COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli,3F4CW@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family WQ51_01275 - - - - - - - - - - - DegV NAGPHGKN_02137 568703.LGG_01399 9.09e-149 419.0 COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,3F578@33958|Lactobacillaceae 91061|Bacilli S protein, hemolysin III hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII NAGPHGKN_02138 568703.LGG_01398 1.48e-118 338.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,3F6Y4@33958|Lactobacillaceae 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 NAGPHGKN_02139 568703.LGG_01397 1.03e-244 670.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,3F3SB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt NAGPHGKN_02140 568703.LGG_01396 0.0 958.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,3FC7W@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn NAGPHGKN_02141 568703.LGG_01396 1.68e-51 178.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,3FC7W@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn NAGPHGKN_02142 568703.LGG_01395 2.08e-110 317.0 2A42J@1|root,30SMC@2|Bacteria,1V54W@1239|Firmicutes,4HGI5@91061|Bacilli,3F3R1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02143 568703.LGG_01394 2.42e-161 459.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,3F3VH@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 NAGPHGKN_02144 568703.LGG_01394 5.47e-101 302.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,3F3VH@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 NAGPHGKN_02145 568703.LGG_01393 2.95e-207 573.0 COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,4H9UY@91061|Bacilli,3F44R@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 ypjC - - - - - - - - - - - DUF2179,YitT_membrane NAGPHGKN_02146 568703.LGG_01392 3.7e-298 814.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,3F3ND@33958|Lactobacillaceae 91061|Bacilli S Tetratricopeptide repeat protein XK27_05225 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 NAGPHGKN_02147 568703.LGG_01391 1.6e-54 171.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,3F6YN@33958|Lactobacillaceae 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding NAGPHGKN_02148 568703.LGG_01390 3.67e-312 850.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,3F4V0@33958|Lactobacillaceae 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 NAGPHGKN_02149 568703.LGG_01389 6.19e-300 820.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,3F4DQ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 NAGPHGKN_02150 568703.LGG_01388 1.09e-149 422.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,3F3W4@33958|Lactobacillaceae 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin NAGPHGKN_02151 568703.LGG_01387 6.23e-87 262.0 COG1388@1|root,COG1388@2|Bacteria,1VFEU@1239|Firmicutes,4HNW5@91061|Bacilli,3F6WV@33958|Lactobacillaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM NAGPHGKN_02152 568703.LGG_01386 0.0 920.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3F4PY@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase RecQ recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind NAGPHGKN_02153 568703.LGG_01385 1.83e-231 637.0 COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HJ71@91061|Bacilli,3F45N@33958|Lactobacillaceae 91061|Bacilli S Helix-turn-helix domain - - - - - - - - - - - - HTH_40 NAGPHGKN_02154 568703.LGG_01384 4.03e-61 187.0 COG1141@1|root,COG1141@2|Bacteria,1VAC2@1239|Firmicutes,4HKG7@91061|Bacilli,3F7KF@33958|Lactobacillaceae 91061|Bacilli C 4Fe-4S single cluster domain of Ferredoxin I fer GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - ko:K05337 - - - - ko00000 - - - Fer4_13 NAGPHGKN_02155 568703.LGG_01383 4.54e-125 357.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,3F4HD@33958|Lactobacillaceae 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt NAGPHGKN_02156 568703.LGG_01382 2.34e-111 323.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,3F402@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 NAGPHGKN_02157 568703.LGG_01382 8.13e-43 146.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,3F402@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 NAGPHGKN_02158 568703.LGG_01381 6.34e-134 380.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,3F5RN@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB NAGPHGKN_02159 568703.LGG_01380 8.93e-163 456.0 COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,3FCCZ@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA NAGPHGKN_02160 568703.LGG_01379 2.81e-88 259.0 COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,3F7QC@33958|Lactobacillaceae 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ribT - - ko:K02859 - - - - ko00000 - - - Acetyltransf_1 NAGPHGKN_02161 568703.LGG_01378 2.09e-212 586.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae 91061|Bacilli D recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase NAGPHGKN_02162 568703.LGG_01377 7.26e-209 577.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli,3F44W@33958|Lactobacillaceae 91061|Bacilli S S1 domain yitL - - ko:K00243 - - - - ko00000 - - - S1_2 NAGPHGKN_02163 568703.LGG_01376 7.15e-94 275.0 COG2707@1|root,COG2707@2|Bacteria,1V7JN@1239|Firmicutes,4IRT9@91061|Bacilli,3FB78@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF441) ytwI - - - - - - - - - - - DUF441 NAGPHGKN_02164 1423732.BALS01000013_gene1583 3.85e-71 217.0 COG0469@1|root,COG3848@1|root,COG0469@2|Bacteria,COG3848@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,3F3JU@33958|Lactobacillaceae 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C NAGPHGKN_02165 568703.LGG_01375 0.0 912.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,3F3JU@33958|Lactobacillaceae 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C NAGPHGKN_02166 568703.LGG_01374 9e-227 625.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,3F4CC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iYO844.BSU29190 PFK NAGPHGKN_02167 568703.LGG_01373 0.0 2141.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,3F4AM@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon NAGPHGKN_02168 568703.LGG_01372 2.92e-38 127.0 2BAS8@1|root,3247E@2|Bacteria,1U6V1@1239|Firmicutes,4IGNY@91061|Bacilli,3F8J0@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2929) - - - - - - - - - - - - DUF2929 NAGPHGKN_02169 568703.LGG_01371 2.15e-187 523.0 2F31P@1|root,33VWT@2|Bacteria,1VWGD@1239|Firmicutes,4HWD9@91061|Bacilli,3F4CP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02170 568703.LGG_01370 0.0 1022.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,3FC24@33958|Lactobacillaceae 91061|Bacilli F 5'-nucleotidase, C-terminal domain ycjM - 3.1.3.5,3.1.3.6,3.1.4.16 ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02370,R02719,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos NAGPHGKN_02171 568703.LGG_01369 2.32e-57 182.0 COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes,4HJXK@91061|Bacilli,3FB3S@33958|Lactobacillaceae 91061|Bacilli K Domain of unknown function (DUF1836) - - - - - - - - - - - - DUF1836 NAGPHGKN_02172 1423732.BALS01000013_gene1573 1.35e-38 128.0 COG0333@1|root,COG0333@2|Bacteria,1VKMZ@1239|Firmicutes,4HR2Q@91061|Bacilli,3F7ZT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p NAGPHGKN_02173 568703.LGG_01367 0.0 1598.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3F3RV@33958|Lactobacillaceae 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N NAGPHGKN_02174 568703.LGG_01366 5.47e-63 193.0 COG5416@1|root,COG5416@2|Bacteria,1VIG5@1239|Firmicutes,4HP5V@91061|Bacilli,3F7IW@33958|Lactobacillaceae 91061|Bacilli S Lipopolysaccharide assembly protein A domain - - - - - - - - - - - - LapA_dom NAGPHGKN_02175 568703.LGG_01365 1.28e-181 506.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,3FC9J@33958|Lactobacillaceae 91061|Bacilli S Enoyl-(Acyl carrier protein) reductase yqjQ - - ko:K07124 - - - - ko00000 - - - adh_short NAGPHGKN_02176 568703.LGG_01364 2.92e-232 639.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,3F4F1@33958|Lactobacillaceae 91061|Bacilli J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 NAGPHGKN_02177 568703.LGG_01363 0.0 1271.0 COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,3F3WT@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase oatA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - - - - - - - - - - Acyl_transf_3 NAGPHGKN_02178 1423732.BALS01000013_gene1567 1.29e-297 813.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,3F4ZA@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 NAGPHGKN_02179 568703.LGG_01361 5.84e-172 480.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli,3F3JB@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR NAGPHGKN_02180 568703.LGG_01360 1.21e-212 588.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,3F3SG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB NAGPHGKN_02181 568703.LGG_01359 0.0 1225.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F44C@33958|Lactobacillaceae 91061|Bacilli GT Phosphotransferase System fruA - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB NAGPHGKN_02182 568703.LGG_01358 0.0 1185.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,3F3MY@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N NAGPHGKN_02183 568703.LGG_01357 1.33e-172 482.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran NAGPHGKN_02184 568703.LGG_01356 0.0 900.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnPH2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1,SBP_bac_3 NAGPHGKN_02185 568703.LGG_01355 2.34e-28 102.0 2AYHS@1|root,31QM8@2|Bacteria,1U8B8@1239|Firmicutes,4II98@91061|Bacilli,3FASP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02186 568703.LGG_01354 2.28e-63 193.0 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli,3F6WJ@33958|Lactobacillaceae 91061|Bacilli S mazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG NAGPHGKN_02187 568703.LGG_01353 4.82e-104 302.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,3F44G@33958|Lactobacillaceae 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 NAGPHGKN_02188 568703.LGG_01352 5.9e-297 810.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,3F41K@33958|Lactobacillaceae 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX NAGPHGKN_02189 568703.LGG_01351 8.34e-271 747.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,3F40B@33958|Lactobacillaceae 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N NAGPHGKN_02190 568703.LGG_01350 5.72e-48 167.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yknV - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran NAGPHGKN_02191 1423816.BACQ01000013_gene458 7.8e-288 800.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yknV - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran NAGPHGKN_02192 568703.LGG_01349 2.93e-85 251.0 COG0789@1|root,COG0789@2|Bacteria,1VB69@1239|Firmicutes,4HN6R@91061|Bacilli,3FC69@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 NAGPHGKN_02193 568703.LGG_01348 1.12e-83 247.0 COG0599@1|root,COG0599@2|Bacteria,1V78I@1239|Firmicutes,4HKFY@91061|Bacilli,3F5I2@33958|Lactobacillaceae 91061|Bacilli S Carboxymuconolactone decarboxylase family pcaC - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD NAGPHGKN_02194 568703.LGG_01347 1.24e-172 481.0 COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HC4I@91061|Bacilli,3F9HM@33958|Lactobacillaceae 91061|Bacilli K Sir2 family - - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 NAGPHGKN_02195 1423816.BACQ01000013_gene462 1.14e-108 324.0 COG5434@1|root,COG5434@2|Bacteria,1TQXN@1239|Firmicutes,4HBHT@91061|Bacilli,3F4Y5@33958|Lactobacillaceae 91061|Bacilli M Protein of unknown function (DUF3737) - - - - - - - - - - - - DUF3737 NAGPHGKN_02196 568703.LGG_01342 4.73e-286 781.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,3F3ZP@33958|Lactobacillaceae 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - ko:K02358,ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 NAGPHGKN_02197 568703.LGG_01341 5.38e-170 478.0 COG0457@1|root,COG0457@2|Bacteria,1W4AR@1239|Firmicutes,4HZIS@91061|Bacilli 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - - NAGPHGKN_02198 568703.LGG_01340 0.0 1100.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3U9@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL NAGPHGKN_02199 568703.LGG_01339 6.79e-152 428.0 29Q46@1|root,30B2W@2|Bacteria,1U7FW@1239|Firmicutes,4IHBY@91061|Bacilli,3F9K7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02200 568703.LGG_01612 0.0 902.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,3F3JV@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N NAGPHGKN_02201 568703.LGG_01612 1.9e-181 538.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,3F3JV@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N NAGPHGKN_02202 568703.LGG_01613 1.85e-59 184.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,3F7ZK@33958|Lactobacillaceae 91061|Bacilli J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae NAGPHGKN_02203 568703.LGG_01614 2.02e-62 191.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,3F7E2@33958|Lactobacillaceae 91061|Bacilli K Protein of unknown function (DUF448) ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 NAGPHGKN_02204 568703.LGG_01615 7.38e-273 748.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,3F3KZ@33958|Lactobacillaceae 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 NAGPHGKN_02205 568703.LGG_01616 3.81e-110 317.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,3F6GZ@33958|Lactobacillaceae 91061|Bacilli J Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C NAGPHGKN_02206 568703.LGG_01617 0.0 2843.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,3F4AN@33958|Lactobacillaceae 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon NAGPHGKN_02207 568703.LGG_01618 0.0 1106.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,3F44A@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit NAGPHGKN_02208 568703.LGG_01619 2.89e-291 796.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,3F3TM@33958|Lactobacillaceae 91061|Bacilli M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 NAGPHGKN_02209 568703.LGG_01620 9.72e-182 506.0 COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli,3FC0H@33958|Lactobacillaceae 91061|Bacilli S Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06255 CTP_transf_1 NAGPHGKN_02210 568703.LGG_01621 2.05e-177 494.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,3F42M@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf NAGPHGKN_02211 568703.LGG_01624 4.96e-121 346.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,3F4X2@33958|Lactobacillaceae 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF NAGPHGKN_02212 568703.LGG_01625 1.96e-165 463.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,3F42J@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase NAGPHGKN_02213 568703.LGG_01627 3.28e-200 555.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,3F459@33958|Lactobacillaceae 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS NAGPHGKN_02214 568703.LGG_01628 9.72e-182 506.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,3F3M1@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 NAGPHGKN_02215 568703.LGG_01629 1.29e-63 194.0 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,3F7G2@33958|Lactobacillaceae 91061|Bacilli L GIY-YIG catalytic domain protein yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG NAGPHGKN_02216 568703.LGG_01630 1.5e-173 484.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,3F4C5@33958|Lactobacillaceae 91061|Bacilli L Methyltransferase small domain yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS NAGPHGKN_02217 568703.LGG_01631 4.02e-158 442.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,3F4QB@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase NAGPHGKN_02218 568703.LGG_01632 2.83e-301 825.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid yhdG - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 NAGPHGKN_02219 568703.LGG_01633 6.05e-177 495.0 COG4420@1|root,COG4420@2|Bacteria,1V46X@1239|Firmicutes,4HI49@91061|Bacilli,3F4FJ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1003) yejC - - - - - - - - - - - DUF1003 NAGPHGKN_02220 568703.LGG_01634 0.0 1137.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NAGPHGKN_02221 568703.LGG_01635 0.0 1131.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran NAGPHGKN_02222 568703.LGG_01636 1.39e-40 134.0 COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,4HNN9@91061|Bacilli,3FCDQ@33958|Lactobacillaceae 91061|Bacilli S UPF0154 protein yneF - - ko:K09976 - - - - ko00000 - - - UPF0154 NAGPHGKN_02223 568703.LGG_01637 3.45e-49 156.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,3F87S@33958|Lactobacillaceae 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 NAGPHGKN_02224 568703.LGG_01638 1.08e-35 120.0 29QDP@1|root,30BCZ@2|Bacteria,1U7XM@1239|Firmicutes,4IHV0@91061|Bacilli,3FAAR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02225 568703.LGG_01639 1.16e-74 223.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,3F6K4@33958|Lactobacillaceae 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 NAGPHGKN_02226 568703.LGG_01640 2.14e-189 525.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,3F3NP@33958|Lactobacillaceae 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT NAGPHGKN_02227 568703.LGG_01641 9.14e-122 347.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,3F74P@33958|Lactobacillaceae 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM NAGPHGKN_02228 568703.LGG_01642 2.2e-51 162.0 COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4HNX0@91061|Bacilli,3F829@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 NAGPHGKN_02229 543734.LCABL_18150 2.97e-59 182.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 NAGPHGKN_02230 568703.LGG_01644 1.02e-301 828.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,3F40R@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB NAGPHGKN_02231 568703.LGG_01645 2.45e-75 225.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli,3F7FG@33958|Lactobacillaceae 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 NAGPHGKN_02232 568703.LGG_01647 1.47e-33 115.0 29QMI@1|root,30BM6@2|Bacteria,1U8B4@1239|Firmicutes,4II94@91061|Bacilli,3FASJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02233 568703.LGG_01648 1.12e-69 210.0 2EU16@1|root,33MI8@2|Bacteria,1VPSM@1239|Firmicutes,4HS7T@91061|Bacilli,3F6QA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02234 568703.LGG_01649 7.44e-232 639.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,3F3YC@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N NAGPHGKN_02235 568703.LGG_01650 0.0 2008.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,3F478@33958|Lactobacillaceae 91061|Bacilli D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge NAGPHGKN_02236 568703.LGG_01651 2.68e-159 447.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,3F564@33958|Lactobacillaceae 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm NAGPHGKN_02237 568703.LGG_01652 0.0 1174.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA1 - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 NAGPHGKN_02238 568703.LGG_01653 6.51e-196 545.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HA7I@91061|Bacilli,3FCB6@33958|Lactobacillaceae 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component oppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N NAGPHGKN_02239 568703.LGG_01654 8.93e-223 615.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,3FCCU@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease oppB - - ko:K02033,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 NAGPHGKN_02240 568703.LGG_01655 5.65e-229 630.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,3F4GM@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY NAGPHGKN_02241 568703.LGG_01656 2.99e-247 678.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3F41T@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY NAGPHGKN_02242 568703.LGG_01658 9.22e-49 155.0 COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,3F7F4@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding NAGPHGKN_02243 568703.LGG_01659 1.16e-240 662.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,3F4N9@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis NAGPHGKN_02244 568703.LGG_01660 0.0 1315.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,3F3JW@33958|Lactobacillaceae 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge NAGPHGKN_02245 568703.LGG_01661 0.0 1010.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,3F3X0@33958|Lactobacillaceae 91061|Bacilli S DAK2 domain fusion protein YloV yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 NAGPHGKN_02246 568703.LGG_01662 5.83e-75 224.0 COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,3F72W@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function yloU - - - - - - - - - - - Asp23 NAGPHGKN_02247 568703.LGG_01663 3.26e-36 122.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli,3F7ZN@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 NAGPHGKN_02248 568703.LGG_01664 1.1e-158 444.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,3F4N8@33958|Lactobacillaceae 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic NAGPHGKN_02249 568703.LGG_01665 1.63e-148 418.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,3F4KX@33958|Lactobacillaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim NAGPHGKN_02250 568703.LGG_01666 2.45e-215 594.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,3F3XH@33958|Lactobacillaceae 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N NAGPHGKN_02251 568703.LGG_01667 0.0 1217.0 COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase NAGPHGKN_02252 568703.LGG_01668 4.47e-175 488.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,3F4UI@33958|Lactobacillaceae 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 NAGPHGKN_02253 568703.LGG_01669 0.0 872.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,3F45F@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB NAGPHGKN_02254 568703.LGG_01670 2.29e-224 619.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,3F4N7@33958|Lactobacillaceae 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N NAGPHGKN_02255 568703.LGG_01671 0.0 1585.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,3F3N8@33958|Lactobacillaceae 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII NAGPHGKN_02256 568703.LGG_01672 3.8e-273 749.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,3F3XX@33958|Lactobacillaceae 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein NAGPHGKN_02257 568703.LGG_01673 4.4e-47 151.0 COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4HNHS@91061|Bacilli,3F81N@33958|Lactobacillaceae 91061|Bacilli K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 NAGPHGKN_02258 568703.LGG_01674 5.09e-148 416.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,3F3X9@33958|Lactobacillaceae 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin NAGPHGKN_02259 568703.LGG_01675 4.46e-156 438.0 COG1752@1|root,COG1752@2|Bacteria,1UXU0@1239|Firmicutes,4IBIE@91061|Bacilli,3F92T@33958|Lactobacillaceae 91061|Bacilli S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin NAGPHGKN_02260 568703.LGG_01676 8.07e-68 205.0 29PXH@1|root,30AVW@2|Bacteria,1U763@1239|Firmicutes,4IH0V@91061|Bacilli,3F90Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02261 568703.LGG_01677 0.0 1062.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,3F43U@33958|Lactobacillaceae 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N NAGPHGKN_02262 568703.LGG_01678 3.59e-97 283.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli,3F71C@33958|Lactobacillaceae 91061|Bacilli K Regulates arginine biosynthesis genes argR2 - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C NAGPHGKN_02263 568703.LGG_01679 4.68e-196 543.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,3F45T@33958|Lactobacillaceae 91061|Bacilli J Ribosomal RNA large subunit methyltransferase J rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 NAGPHGKN_02264 568703.LGG_01680 2.27e-186 520.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,3F436@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt NAGPHGKN_02265 568703.LGG_01681 2.87e-43 141.0 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,3F81K@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S NAGPHGKN_02266 568703.LGG_01682 2.58e-310 847.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,3F4RE@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 NAGPHGKN_02267 568703.LGG_01683 9.8e-197 546.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,3F46A@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C NAGPHGKN_02268 568703.LGG_01684 1.29e-87 258.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,3F7KW@33958|Lactobacillaceae 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB NAGPHGKN_02269 568703.LGG_01685 8.72e-100 290.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,3F71X@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function WQ51_04310 - - ko:K10947 - - - - ko00000,ko03000 - - - Asp23 NAGPHGKN_02270 568703.LGG_01686 4.27e-132 374.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F422@33958|Lactobacillaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C NAGPHGKN_02271 568703.LGG_01687 1.51e-259 711.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,3F4DR@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 NAGPHGKN_02272 543734.LCABL_18600 1.6e-63 194.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,3F6WU@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 NAGPHGKN_02273 568703.LGG_01689 4.18e-73 219.0 COG2868@1|root,COG2868@2|Bacteria,1VEQ9@1239|Firmicutes,4HNMV@91061|Bacilli,3F839@33958|Lactobacillaceae 91061|Bacilli J Cysteine protease Prp ysxB - - ko:K07584 - - - - ko00000 - - - Peptidase_Prp NAGPHGKN_02274 568703.LGG_01690 1.18e-66 202.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,3F6WT@33958|Lactobacillaceae 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p NAGPHGKN_02275 568703.LGG_01691 5.41e-43 140.0 29QDE@1|root,30BCP@2|Bacteria,1U7X3@1239|Firmicutes,4IHUF@91061|Bacilli,3FAA2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02276 568703.LGG_01692 1.77e-20 81.3 29QJP@1|root,30BJ9@2|Bacteria,1U87T@1239|Firmicutes,4II5H@91061|Bacilli,3FANH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02277 568703.LGG_01693 2.69e-297 810.0 COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,4HITC@91061|Bacilli,3F50M@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - NAGPHGKN_02279 568703.LGG_01694 0.0 911.0 COG1132@1|root,COG1132@2|Bacteria,1V08F@1239|Firmicutes,4HTAU@91061|Bacilli,3F517@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NAGPHGKN_02280 568703.LGG_01695 0.0 1567.0 COG2936@1|root,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4HBA0@91061|Bacilli,3F44E@33958|Lactobacillaceae 91061|Bacilli E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline pepX - 3.4.14.11 ko:K01281 - - - - ko00000,ko01000,ko01002 - - - PepX_C,PepX_N,Peptidase_S15 NAGPHGKN_02281 568703.LGG_01696 0.0 909.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,3F41A@33958|Lactobacillaceae 91061|Bacilli E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N NAGPHGKN_02282 568703.LGG_01697 5.4e-80 237.0 COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli,3F7RX@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - MerR_1 NAGPHGKN_02283 568703.LGG_01698 0.0 1362.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,3F3TV@33958|Lactobacillaceae 91061|Bacilli E Orn/Lys/Arg decarboxylase, C-terminal domain speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.17,4.1.1.18,4.1.1.19 ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 M00133,M00134 R00462,R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C NAGPHGKN_02284 568703.LGG_01699 6.73e-305 831.0 COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,3F3PU@33958|Lactobacillaceae 91061|Bacilli P aluminum resistance ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - - - - - - - - - - Met_gamma_lyase NAGPHGKN_02285 568703.LGG_01700 3.41e-231 636.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,3F3XS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT NAGPHGKN_02286 568703.LGG_01701 2.75e-34 117.0 2C91M@1|root,33E1E@2|Bacteria,1VPEZ@1239|Firmicutes,4HRR2@91061|Bacilli,3F8C0@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3042) WQ51_02665 - - - - - - - - - - - DUF3042 NAGPHGKN_02287 568703.LGG_01702 6.47e-95 276.0 COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,3F67E@33958|Lactobacillaceae 91061|Bacilli P Rhodanese-like protein yqhL - - - - - - - - - - - Rhodanese NAGPHGKN_02288 568703.LGG_01703 4.82e-227 625.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,3F4F0@33958|Lactobacillaceae 91061|Bacilli G Glucokinase glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK NAGPHGKN_02289 568703.LGG_01704 1.37e-54 170.0 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli,3F83I@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF910) yqgQ - - - - - - - - - - - DUF910 NAGPHGKN_02290 568703.LGG_01705 8.99e-157 440.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,3F3WR@33958|Lactobacillaceae 91061|Bacilli S Peptidase, S54 family gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 NAGPHGKN_02291 568703.LGG_01706 0.0 1374.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,3F3KH@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbp2b - - ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase NAGPHGKN_02292 568703.LGG_01708 0.0 1725.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HCR9@91061|Bacilli,3FC7P@33958|Lactobacillaceae 91061|Bacilli S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO NAGPHGKN_02293 568703.LGG_01709 1.91e-70 211.0 COG4841@1|root,COG4841@2|Bacteria,1VEQE@1239|Firmicutes,4HNU2@91061|Bacilli,3F7SB@33958|Lactobacillaceae 91061|Bacilli S Belongs to the HesB IscA family yneR - - - - - - - - - - - Fe-S_biosyn NAGPHGKN_02294 568703.LGG_01710 3.39e-148 418.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,3F4DN@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Lux Regulon vraR - - ko:K07694,ko:K11618 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg NAGPHGKN_02295 568703.LGG_01711 2.79e-234 647.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,3FC2U@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase vraS - 2.7.13.3 ko:K07681,ko:K11617 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 NAGPHGKN_02296 568703.LGG_01712 2.31e-166 465.0 COG4758@1|root,COG4758@2|Bacteria,1V3D0@1239|Firmicutes,4HDIA@91061|Bacilli,3F5S1@33958|Lactobacillaceae 91061|Bacilli S Cell wall-active antibiotics response 4TMS YvqF yvqF - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 NAGPHGKN_02297 568703.LGG_01713 6.1e-101 293.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,3F4ZF@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N NAGPHGKN_02298 568703.LGG_01714 1.98e-147 415.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli,3F3KE@33958|Lactobacillaceae 91061|Bacilli F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK NAGPHGKN_02299 568703.LGG_01715 2.75e-267 733.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,3F4IG@33958|Lactobacillaceae 91061|Bacilli S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG NAGPHGKN_02300 568703.LGG_01717 0.0 1580.0 COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,3F3V3@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind NAGPHGKN_02301 568703.LGG_01718 1.21e-91 275.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,3F4NT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d NAGPHGKN_02302 568703.LGG_01718 2.11e-148 423.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,3F4NT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d NAGPHGKN_02303 568703.LGG_01719 1.44e-90 265.0 COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,3F7FK@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, HxlR family yodB GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HxlR NAGPHGKN_02304 568703.LGG_01720 2.26e-106 307.0 COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,4HHW0@91061|Bacilli,3F64N@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. XK27_09705 - - ko:K06950 - - - - ko00000 - - - HD NAGPHGKN_02305 568703.LGG_01721 5e-175 488.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,3F3NF@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind NAGPHGKN_02306 568703.LGG_01723 1.45e-60 186.0 COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,4HNN7@91061|Bacilli,3F81R@33958|Lactobacillaceae 91061|Bacilli C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020 Acylphosphatase NAGPHGKN_02307 568703.LGG_01724 9.37e-230 633.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli,3F3P3@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP NAGPHGKN_02308 568703.LGG_01725 0.0 991.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,3F3NU@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA NAGPHGKN_02309 543734.LCABL_18980 1.01e-157 442.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,3F421@33958|Lactobacillaceae 91061|Bacilli K response regulator csrR - - - - - - - - - - - Response_reg,Trans_reg_C NAGPHGKN_02310 568703.LGG_01727 0.0 938.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,3F3S8@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 NAGPHGKN_02311 568703.LGG_01731 1.14e-122 350.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,3F61Z@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized ACR, COG1399 ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 NAGPHGKN_02312 568703.LGG_01732 3.45e-263 722.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,3F3QC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 NAGPHGKN_02313 568703.LGG_01733 1.19e-178 497.0 COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,4HD2W@91061|Bacilli,3F4KM@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase yqeM - - - - - - - - - - - Methyltransf_25 NAGPHGKN_02314 568703.LGG_01734 1.68e-78 233.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,3F7QN@33958|Lactobacillaceae 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS NAGPHGKN_02315 568703.LGG_01735 9.21e-142 400.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,3F47C@33958|Lactobacillaceae 91061|Bacilli H Hydrolase, HD family yqeK - - - - - - - - - - - HD NAGPHGKN_02316 1423816.BACQ01000007_gene136 1.19e-150 424.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,3F4D6@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like NAGPHGKN_02317 568703.LGG_01737 7.67e-63 192.0 COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,3F7EW@33958|Lactobacillaceae 91061|Bacilli J RNA-binding protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY NAGPHGKN_02318 568703.LGG_01738 9.33e-275 751.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,3F4JU@33958|Lactobacillaceae 91061|Bacilli S Ribosome biogenesis GTPase YqeH yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 NAGPHGKN_02319 568703.LGG_01739 4.16e-125 356.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,3F46V@33958|Lactobacillaceae 91061|Bacilli S HAD phosphatase, family IIIA yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase NAGPHGKN_02320 568703.LGG_01740 4.06e-213 588.0 COG0346@1|root,COG0346@2|Bacteria,1VWUR@1239|Firmicutes,4HXTS@91061|Bacilli,3FB66@33958|Lactobacillaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ykcA - - - - - - - - - - - Glyoxalase NAGPHGKN_02321 568703.LGG_01741 3.2e-242 664.0 COG0346@1|root,COG0346@2|Bacteria,1TP7I@1239|Firmicutes,4H9ND@91061|Bacilli,3F4PB@33958|Lactobacillaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily mhqA_2 - - ko:K15975 - - - - ko00000 - - - Glyoxalase NAGPHGKN_02322 568703.LGG_01742 8.79e-156 436.0 COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,4HB45@91061|Bacilli,3F6EM@33958|Lactobacillaceae 91061|Bacilli S Dienelactone hydrolase family mhqD - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2,DLH NAGPHGKN_02323 568703.LGG_01743 2.91e-229 631.0 COG0604@1|root,COG0604@2|Bacteria,1V7QI@1239|Firmicutes,4HJMD@91061|Bacilli,3F69N@33958|Lactobacillaceae 91061|Bacilli C Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 NAGPHGKN_02324 568703.LGG_01744 4.79e-129 367.0 COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4HE2X@91061|Bacilli,3F5U4@33958|Lactobacillaceae 91061|Bacilli S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox NAGPHGKN_02325 568703.LGG_01745 1.44e-74 223.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,3F6HZ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 NAGPHGKN_02326 543734.LCABL_19160 1.13e-36 124.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,3F7CQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p NAGPHGKN_02327 568703.LGG_01747 2.6e-101 294.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,3F4MS@33958|Lactobacillaceae 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N NAGPHGKN_02328 1231336.L248_2850 7.83e-292 833.0 COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,4HCQK@91061|Bacilli,3F5TC@33958|Lactobacillaceae 91061|Bacilli O ATPase family associated with various cellular activities (AAA) spoVK - - - - - - - - - - - AAA,Beta_helix NAGPHGKN_02329 1423807.BACO01000060_gene1745 9.99e-05 47.4 29PXS@1|root,30AW5@2|Bacteria,1U76J@1239|Firmicutes,4IH1A@91061|Bacilli,3F91E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02331 1122149.BACN01000061_gene1861 1.28e-29 109.0 COG2378@1|root,COG2378@2|Bacteria 2|Bacteria K regulation of single-species biofilm formation - - - - - - - - - - - - HTH_11 NAGPHGKN_02332 1122149.BACN01000061_gene1862 1.71e-28 110.0 COG2378@1|root,COG2378@2|Bacteria,1U82G@1239|Firmicutes,4IHZV@91061|Bacilli,3FAG6@33958|Lactobacillaceae 91061|Bacilli K WYL domain - - - - - - - - - - - - WYL NAGPHGKN_02333 568703.LGG_01752 1.19e-160 450.0 2DMFR@1|root,32R83@2|Bacteria,1VJJ0@1239|Firmicutes,4HQP8@91061|Bacilli,3F9AJ@33958|Lactobacillaceae 91061|Bacilli S SseB protein N-terminal domain - - - - - - - - - - - - SseB,SseB_C NAGPHGKN_02334 568703.LGG_01753 5.87e-86 253.0 29Q5P@1|root,30B4K@2|Bacteria,1U7IT@1239|Firmicutes,4IHFJ@91061|Bacilli,3F9S3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02335 568703.LGG_01754 0.0 1323.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,3F3TC@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD NAGPHGKN_02336 568703.LGG_01756 3.91e-217 600.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,3F4JK@33958|Lactobacillaceae 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 NAGPHGKN_02337 568703.LGG_01757 6.82e-91 278.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,3F5D7@33958|Lactobacillaceae 91061|Bacilli L replication initiation and membrane attachment dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 NAGPHGKN_02338 568703.LGG_01757 1.84e-180 510.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,3F5D7@33958|Lactobacillaceae 91061|Bacilli L replication initiation and membrane attachment dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 NAGPHGKN_02339 568703.LGG_01758 3.55e-104 301.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,3F65S@33958|Lactobacillaceae 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone NAGPHGKN_02340 568703.LGG_01759 4.88e-133 378.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,3F6WF@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE NAGPHGKN_02341 568703.LGG_01760 5.95e-202 559.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,3F43E@33958|Lactobacillaceae 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS NAGPHGKN_02342 568703.LGG_01761 0.0 1728.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,3F3ZA@33958|Lactobacillaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A NAGPHGKN_02343 568703.LGG_01762 1.65e-151 427.0 COG0670@1|root,COG0670@2|Bacteria,1V9CJ@1239|Firmicutes,4HM3D@91061|Bacilli,3FBMQ@33958|Lactobacillaceae 91061|Bacilli S Inhibitor of apoptosis-promoting Bax1 ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I NAGPHGKN_02344 568703.LGG_01763 7.54e-242 665.0 COG4072@1|root,COG4072@2|Bacteria,1VCXS@1239|Firmicutes,4HKJG@91061|Bacilli,3F5HA@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein - - - - - - - - - - - - DUF3324,DUF916 NAGPHGKN_02346 568703.LGG_01765 2.02e-174 488.0 29Q0J@1|root,30AZ1@2|Bacteria,1U7AF@1239|Firmicutes,4IH5E@91061|Bacilli,3F97I@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL NAGPHGKN_02347 568703.LGG_01766 0.0 2111.0 COG5492@1|root,COG5492@2|Bacteria,1TVFF@1239|Firmicutes,4I2CX@91061|Bacilli,3F9JA@33958|Lactobacillaceae 91061|Bacilli N domain, Protein - - - - - - - - - - - - - NAGPHGKN_02348 568703.LGG_01767 0.0 912.0 COG3711@1|root,COG3711@2|Bacteria,1V0R0@1239|Firmicutes,4HE1S@91061|Bacilli 91061|Bacilli K Mga helix-turn-helix domain XK27_00195 - - - - - - - - - - - Mga NAGPHGKN_02349 568703.LGG_01768 0.0 874.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,3F49J@33958|Lactobacillaceae 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M NAGPHGKN_02350 568703.LGG_01769 0.0 1290.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,3F441@33958|Lactobacillaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma NAGPHGKN_02352 568703.LGG_01771 1.63e-146 413.0 COG0073@1|root,COG0073@2|Bacteria,1V7QA@1239|Firmicutes,4HJBD@91061|Bacilli,3FBJ0@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily XK27_10290 - - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind NAGPHGKN_02353 568703.LGG_01772 4.38e-72 216.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,3F72K@33958|Lactobacillaceae 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin NAGPHGKN_02355 568703.LGG_01774 1.11e-154 434.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,3F3QM@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 NAGPHGKN_02356 568703.LGG_01775 3.86e-190 527.0 COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,3F4GU@33958|Lactobacillaceae 91061|Bacilli M Choline/ethanolamine kinase ytmP - - - - - - - - - - - APH NAGPHGKN_02357 1423732.BALS01000048_gene2577 0.000128 45.8 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS NAGPHGKN_02358 568703.LGG_01776 4.2e-284 777.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,3F4HH@33958|Lactobacillaceae 91061|Bacilli U ABC transporter ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB NAGPHGKN_02359 568703.LGG_01777 3.79e-29 109.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,3F444@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_02360 568703.LGG_01777 1.34e-125 361.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,3F444@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_02361 568703.LGG_01778 1.14e-96 281.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,3F6K5@33958|Lactobacillaceae 91061|Bacilli FG histidine triad hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT NAGPHGKN_02362 568703.LGG_01779 3.17e-61 191.0 COG4980@1|root,COG4980@2|Bacteria,1VM8M@1239|Firmicutes,4HR25@91061|Bacilli,3F7TT@33958|Lactobacillaceae 91061|Bacilli S YtxH-like protein - - - - - - - - - - - - YtxH NAGPHGKN_02363 568703.LGG_01780 2.5e-203 564.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,3F45W@33958|Lactobacillaceae 91061|Bacilli M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 NAGPHGKN_02364 568703.LGG_01781 3.57e-233 641.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,3F4SF@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon NAGPHGKN_02365 568703.LGG_01782 3.88e-73 219.0 COG3679@1|root,COG3679@2|Bacteria,1V62T@1239|Firmicutes,4IRH3@91061|Bacilli,3FBP8@33958|Lactobacillaceae 91061|Bacilli S Control of competence regulator ComK, YlbF/YmcA - - - - - - - - - - - - Com_YlbF NAGPHGKN_02366 568703.LGG_01783 0.0 1347.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F49Q@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein pbp2A - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase NAGPHGKN_02367 568703.LGG_01784 1.4e-198 550.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,3F50K@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 NAGPHGKN_02368 568703.LGG_01785 2.72e-97 283.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HN5H@91061|Bacilli,3FBR5@33958|Lactobacillaceae 91061|Bacilli K Regulates arginine biosynthesis genes argR1 - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C NAGPHGKN_02369 568703.LGG_01786 9.47e-48 166.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,3F4DE@33958|Lactobacillaceae 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d NAGPHGKN_02370 568703.LGG_01786 0.0 924.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,3F4DE@33958|Lactobacillaceae 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d NAGPHGKN_02372 568703.LGG_01787 3.28e-87 256.0 2A8KV@1|root,30XP9@2|Bacteria,1U6R7@1239|Firmicutes,4IGII@91061|Bacilli,3F8CJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02373 568703.LGG_01788 1.93e-30 107.0 29QNK@1|root,30BN8@2|Bacteria,1U8CT@1239|Firmicutes,4IIAS@91061|Bacilli,3FAUE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02374 568703.LGG_01789 3.26e-226 623.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HBFE@91061|Bacilli,3FC4P@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of dihydroorotate to orotate pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.5.2,1.3.98.1 ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh NAGPHGKN_02375 568703.LGG_01790 0.0 1091.0 COG0584@1|root,COG4781@1|root,COG0584@2|Bacteria,COG4781@2|Bacteria,1UG1C@1239|Firmicutes,4HCPQ@91061|Bacilli,3F3SZ@33958|Lactobacillaceae 91061|Bacilli C phosphodiesterase glpQ4 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,GPDPase_memb NAGPHGKN_02376 568703.LGG_01791 1.1e-156 440.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HID6@91061|Bacilli,3F5G4@33958|Lactobacillaceae 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K16511 - - - - ko00000 - - - MecA NAGPHGKN_02377 543734.LCABL_19550 1.9e-72 219.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F6HJ@33958|Lactobacillaceae 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC NAGPHGKN_02378 568703.LGG_01793 1.63e-176 491.0 COG1234@1|root,COG1234@2|Bacteria,1V1TF@1239|Firmicutes,4HFNV@91061|Bacilli,3F4U0@33958|Lactobacillaceae 91061|Bacilli S Metallo-beta-lactamase superfamily yhfI GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - - - - - - - - - - Lactamase_B,Lactamase_B_2 NAGPHGKN_02379 568703.LGG_01794 9.97e-119 339.0 COG2329@1|root,COG2329@2|Bacteria,1U6YF@1239|Firmicutes,4IGSM@91061|Bacilli,3F8QA@33958|Lactobacillaceae 91061|Bacilli S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - - NAGPHGKN_02380 568703.LGG_01795 0.0 1267.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli,3F5VK@33958|Lactobacillaceae 91061|Bacilli V ABC transporter (permease) - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX NAGPHGKN_02381 568703.LGG_01796 5.63e-178 496.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3F5FY@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_02382 568703.LGG_01798 5.24e-158 443.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli,3F5NZ@33958|Lactobacillaceae 91061|Bacilli K response regulator rrp1 - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C NAGPHGKN_02383 568703.LGG_01799 1.03e-263 722.0 COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,4HCB6@91061|Bacilli,3FBXD@33958|Lactobacillaceae 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - ko:K19168 - - - - ko00000,ko02048 - - - HATPase_c NAGPHGKN_02384 568703.LGG_01800 1.09e-139 394.0 COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HGJ9@91061|Bacilli,3F46H@33958|Lactobacillaceae 91061|Bacilli O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM NAGPHGKN_02385 568703.LGG_01801 0.0 1354.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,3F4IX@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase copB - 3.6.3.3,3.6.3.4,3.6.3.5 ko:K01533,ko:K01534 - - R00086 RC00002 ko00000,ko01000 3.A.3.5,3.A.3.6 - - E1-E2_ATPase,Hydrolase NAGPHGKN_02386 568703.LGG_01802 6.75e-101 292.0 COG3682@1|root,COG3682@2|Bacteria,1VA7Q@1239|Firmicutes,4HKGF@91061|Bacilli,3F7D0@33958|Lactobacillaceae 91061|Bacilli K Copper transport repressor CopY TcrY copR - - ko:K02171 ko01501,map01501 M00627 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Penicillinase_R NAGPHGKN_02387 568703.LGG_01803 1.59e-286 784.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,3F4Z8@33958|Lactobacillaceae 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N NAGPHGKN_02388 568703.LGG_01805 1.72e-137 401.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,3F4FD@33958|Lactobacillaceae 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS NAGPHGKN_02389 568703.LGG_02305 2.27e-89 271.0 COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBKP@91061|Bacilli,3F431@33958|Lactobacillaceae 91061|Bacilli L Putative transposase DNA-binding domain tnpB - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon NAGPHGKN_02390 568703.LGG_02270 5.51e-82 265.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli,3F3PY@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504 2.A.1.3.37 - iYO844.BG12900 DUF2156,LPG_synthase_TM NAGPHGKN_02391 568703.LGG_02270 0.0 1333.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli,3F3PY@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504 2.A.1.3.37 - iYO844.BG12900 DUF2156,LPG_synthase_TM NAGPHGKN_02392 568703.LGG_02269 3.34e-139 393.0 COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HHCA@91061|Bacilli,3F4NU@33958|Lactobacillaceae 91061|Bacilli J Methyltransferase rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS NAGPHGKN_02393 568703.LGG_02268 5.69e-65 198.0 2EMDH@1|root,33F2E@2|Bacteria,1VKX3@1239|Firmicutes,4HR5Y@91061|Bacilli,3F709@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02394 568703.LGG_02267 5.13e-113 325.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,3F6IS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam NAGPHGKN_02395 568703.LGG_02266 0.0 1089.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,3F3P2@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 NAGPHGKN_02396 568703.LGG_02265 2.29e-50 161.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,3F7F3@33958|Lactobacillaceae 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd NAGPHGKN_02397 568703.LGG_02264 2.17e-140 396.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,3F4JQ@33958|Lactobacillaceae 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 NAGPHGKN_02398 568703.LGG_02263 1.35e-51 163.0 2DKQT@1|root,30ADD@2|Bacteria,1U6HS@1239|Firmicutes,4IGA3@91061|Bacilli,3F7Y1@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2508) - - - - - - - - - - - - DUF2508 NAGPHGKN_02399 568703.LGG_02262 6.06e-134 380.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,3F4JR@33958|Lactobacillaceae 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin NAGPHGKN_02400 568703.LGG_02261 2.31e-69 209.0 COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,3F6VW@33958|Lactobacillaceae 91061|Bacilli S Cyclic-di-AMP receptor yaaQ - - - - - - - - - - - CdAMP_rec NAGPHGKN_02401 568703.LGG_02260 2.38e-225 622.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,3F50D@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C NAGPHGKN_02402 568703.LGG_02259 2.27e-75 225.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli,3F864@33958|Lactobacillaceae 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB NAGPHGKN_02403 568703.LGG_02258 1.56e-194 540.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,3F4AI@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase NAGPHGKN_02404 568703.LGG_02257 4.51e-184 511.0 COG3884@1|root,COG3884@2|Bacteria,1V3RB@1239|Firmicutes,4HHJ4@91061|Bacilli,3F41B@33958|Lactobacillaceae 91061|Bacilli I Acyl-ACP thioesterase fat - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE NAGPHGKN_02405 568703.LGG_02256 8.71e-232 638.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli,3F3XA@33958|Lactobacillaceae 91061|Bacilli EJ Asparaginase ansB - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase NAGPHGKN_02406 568703.LGG_02255 4.02e-116 333.0 COG3275@1|root,COG3275@2|Bacteria,1VB87@1239|Firmicutes,4ISET@91061|Bacilli,3FBSH@33958|Lactobacillaceae 91061|Bacilli T ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt NAGPHGKN_02407 568703.LGG_02253 7.32e-153 431.0 2AQ5J@1|root,31FAY@2|Bacteria,1U7CF@1239|Firmicutes,4IH7T@91061|Bacilli,3F9CK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02408 568703.LGG_02252 3.82e-168 470.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,3F3WV@33958|Lactobacillaceae 91061|Bacilli O Universal bacterial protein YeaZ yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 NAGPHGKN_02409 568703.LGG_02251 1.06e-127 362.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,3F522@33958|Lactobacillaceae 91061|Bacilli K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 NAGPHGKN_02410 568703.LGG_02250 4.36e-240 660.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,3F4AX@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 NAGPHGKN_02411 568703.LGG_02249 6.92e-66 201.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F6GU@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit ptcB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB NAGPHGKN_02412 568703.LGG_02248 0.0 1259.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,3F3QI@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn NAGPHGKN_02413 568703.LGG_02247 7.76e-152 427.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,3F40G@33958|Lactobacillaceae 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N NAGPHGKN_02414 568703.LGG_02246 7.06e-81 239.0 COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,3F7AX@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR NAGPHGKN_02415 568703.LGG_02245 4.17e-204 565.0 COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,4HA3P@91061|Bacilli,3FC3A@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01990,ko:K16921 ko02010,map02010 M00254,M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_02416 568703.LGG_02244 6.27e-248 681.0 2DKT0@1|root,30APV@2|Bacteria,1U6YM@1239|Firmicutes,4IGSU@91061|Bacilli,3F8QM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02417 568703.LGG_02242 4.11e-251 689.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr NAGPHGKN_02418 568703.LGG_02241 1.23e-142 403.0 COG1266@1|root,COG1266@2|Bacteria,1UZGJ@1239|Firmicutes,4HFCB@91061|Bacilli,3F5JU@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity ydiL - - ko:K07052 - - - - ko00000 - - - Abi NAGPHGKN_02419 543734.LCABL_24210 1.7e-59 183.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,3F7CZ@33958|Lactobacillaceae 91061|Bacilli O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 NAGPHGKN_02420 568703.LGG_02239 0.0 1009.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,3F3MM@33958|Lactobacillaceae 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 NAGPHGKN_02421 568703.LGG_02238 7.56e-75 224.0 2EUB0@1|root,33MTD@2|Bacteria,1W3MW@1239|Firmicutes,4HZUX@91061|Bacilli,3F7TK@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1827) - - - - - - - - - - - - DUF1827 NAGPHGKN_02422 568703.LGG_02236 0.0 1150.0 COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,4HAZH@91061|Bacilli,3F44Y@33958|Lactobacillaceae 91061|Bacilli E amino acid ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 NAGPHGKN_02424 568703.LGG_02235 0.0 1657.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,3F4A5@33958|Lactobacillaceae 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V NAGPHGKN_02425 568703.LGG_02234 0.0 1261.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,3F3PK@33958|Lactobacillaceae 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C NAGPHGKN_02426 568703.LGG_02233 1.43e-123 352.0 COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli,3F65C@33958|Lactobacillaceae 91061|Bacilli D nucleoside-triphosphate diphosphatase activity maf GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K06287 - - - - ko00000 - - - Maf NAGPHGKN_02427 568703.LGG_02232 1.08e-107 311.0 2C9UQ@1|root,309VR@2|Bacteria,1U5T4@1239|Firmicutes,4IFH1@91061|Bacilli,3F6FU@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4811) - - - - - - - - - - - - DUF4811 NAGPHGKN_02428 568703.LGG_02231 0.0 909.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 NAGPHGKN_02429 568703.LGG_02230 3.95e-253 692.0 COG3594@1|root,COG3594@2|Bacteria,1V08V@1239|Firmicutes,4IRX9@91061|Bacilli,3F5QM@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase - - - - - - - - - - - - Acyl_transf_3 NAGPHGKN_02430 568703.LGG_02229 2.21e-184 513.0 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 NAGPHGKN_02431 568703.LGG_02228 0.0 888.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3TX@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain yhdP - - - - - - - - - - - CBS,CorC_HlyC,DUF21 NAGPHGKN_02432 568703.LGG_02227 1.82e-175 489.0 COG4295@1|root,COG4295@2|Bacteria,1VAHN@1239|Firmicutes,4HY6J@91061|Bacilli,3FBBD@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2263) - - - - - - - - - - - - DUF2263 NAGPHGKN_02433 568703.LGG_02226 1.71e-145 410.0 COG0518@1|root,COG0518@2|Bacteria,1UAH0@1239|Firmicutes,4HHTX@91061|Bacilli,3F4AV@33958|Lactobacillaceae 91061|Bacilli F glutamine amidotransferase - - - - - - - - - - - - GATase NAGPHGKN_02434 568703.LGG_02225 3.75e-142 412.0 COG3103@1|root,COG3103@2|Bacteria,1VB6H@1239|Firmicutes,4I1GZ@91061|Bacilli,3F66H@33958|Lactobacillaceae 91061|Bacilli T Sh3 type 3 domain protein - - - - - - - - - - - - LysM,SLAP NAGPHGKN_02435 568703.LGG_02224 5.22e-132 375.0 COG0500@1|root,COG0500@2|Bacteria,1U7E4@1239|Firmicutes,4IHA0@91061|Bacilli,3F9GA@33958|Lactobacillaceae 91061|Bacilli Q methyltransferase - - - - - - - - - - - - - NAGPHGKN_02437 568703.LGG_02223 2.46e-114 329.0 COG1268@1|root,COG1268@2|Bacteria,1VAAD@1239|Firmicutes,4HI8T@91061|Bacilli,3F6YG@33958|Lactobacillaceae 91061|Bacilli S BioY family bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY NAGPHGKN_02438 568703.LGG_02222 2.11e-82 243.0 29PE3@1|root,30ABP@2|Bacteria,1U6FN@1239|Firmicutes,4IG7M@91061|Bacilli,3F7TB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02439 568703.LGG_02221 5.06e-282 769.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,3F5I3@33958|Lactobacillaceae 91061|Bacilli C Domain of unknown function (DUF1730) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 NAGPHGKN_02440 568703.LGG_02220 4.49e-187 520.0 COG2365@1|root,COG2365@2|Bacteria,1VBGE@1239|Firmicutes,4HN6J@91061|Bacilli,3FBJY@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family ptp3 - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 NAGPHGKN_02441 568703.LGG_02218 8.34e-86 253.0 29Q5Z@1|root,30B4V@2|Bacteria,1U7J6@1239|Firmicutes,4IHG0@91061|Bacilli,3F9SW@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_31 NAGPHGKN_02442 568703.LGG_02217 1.94e-100 291.0 COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,4HNHG@91061|Bacilli,3F4Z0@33958|Lactobacillaceae 91061|Bacilli T universal stress protein usp5 - - - - - - - - - - - Usp NAGPHGKN_02443 568703.LGG_02215 5.33e-57 182.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,3F5KA@33958|Lactobacillaceae 91061|Bacilli L glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco NAGPHGKN_02444 568703.LGG_02215 1.19e-71 219.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,3F5KA@33958|Lactobacillaceae 91061|Bacilli L glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco NAGPHGKN_02445 568703.LGG_02214 3.9e-180 504.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA NAGPHGKN_02446 568703.LGG_02213 1.57e-34 117.0 29PYW@1|root,30AXC@2|Bacteria,1U786@1239|Firmicutes,4IH32@91061|Bacilli,3F93Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02447 1423732.BALS01000008_gene845 4.28e-11 60.5 2CCK1@1|root,309S4@2|Bacteria,1U5KG@1239|Firmicutes,4IFBA@91061|Bacilli,3F64Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02448 568703.LGG_02212 5.73e-86 254.0 2CCK1@1|root,309S4@2|Bacteria,1U5KG@1239|Firmicutes,4IFBA@91061|Bacilli,3F64Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02449 568703.LGG_02211 3.38e-50 159.0 2900D@1|root,2ZMQP@2|Bacteria,1W1YJ@1239|Firmicutes,4I01F@91061|Bacilli,3F8VC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02450 568703.LGG_02210 8.01e-231 637.0 COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,4HCES@91061|Bacilli,3F5RC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism add - 3.5.4.2,3.5.4.4 ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 M00236 R01244,R01560,R02556 RC00477 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - A_deaminase NAGPHGKN_02451 568703.LGG_02209 9.73e-249 687.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,3F45P@33958|Lactobacillaceae 91061|Bacilli F pyrimidine-nucleoside phosphorylase pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C NAGPHGKN_02452 568703.LGG_02209 1.9e-33 125.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,3F45P@33958|Lactobacillaceae 91061|Bacilli F pyrimidine-nucleoside phosphorylase pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C NAGPHGKN_02453 568703.LGG_02208 0.0 967.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,3F4MJ@33958|Lactobacillaceae 91061|Bacilli C ubiquinol oxidase cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I NAGPHGKN_02454 568703.LGG_02207 4.14e-232 640.0 COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,4H9KF@91061|Bacilli,3F40S@33958|Lactobacillaceae 91061|Bacilli C Cytochrome d ubiquinol oxidase subunit II cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iYO844.BSU38750 Cyt_bd_oxida_II NAGPHGKN_02455 568703.LGG_02206 0.0 1130.0 COG4988@1|root,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,4HAN0@91061|Bacilli,3F451@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD cydC GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran NAGPHGKN_02456 568703.LGG_02205 0.0 1134.0 COG4987@1|root,COG4987@2|Bacteria,1UHN5@1239|Firmicutes,4HAAB@91061|Bacilli,3F4PG@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC cydD - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran NAGPHGKN_02458 568703.LGG_02198 1.77e-227 630.0 COG3409@1|root,COG3409@2|Bacteria,1V2YC@1239|Firmicutes,4HFNB@91061|Bacilli,3F6TH@33958|Lactobacillaceae 91061|Bacilli M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - - NAGPHGKN_02459 568703.LGG_02197 6.36e-98 284.0 COG5341@1|root,COG5341@2|Bacteria,1VCR8@1239|Firmicutes,4HKP0@91061|Bacilli,3FBC0@33958|Lactobacillaceae 91061|Bacilli S NusG domain II - - - - - - - - - - - - NusG_II NAGPHGKN_02460 568703.LGG_02196 0.0 1065.0 COG4988@1|root,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,4HCDA@91061|Bacilli,3F4VY@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter transmembrane region cydD1 - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran,DUF454 NAGPHGKN_02461 568703.LGG_02195 0.0 985.0 COG1132@1|root,COG1132@2|Bacteria,1UHQP@1239|Firmicutes,4HC57@91061|Bacilli,3F5XV@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region msbA9 - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran NAGPHGKN_02462 568703.LGG_02194 1.99e-204 566.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,3F4SJ@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain bglG4 - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD NAGPHGKN_02463 568703.LGG_02192 0.0 1138.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system bglP - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NAGPHGKN_02464 1423732.BALS01000018_gene1810 0.0 886.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglH - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 NAGPHGKN_02465 568703.LGG_02189 1.69e-186 518.0 COG1028@1|root,COG1028@2|Bacteria,1TRQC@1239|Firmicutes,4HD7P@91061|Bacilli,3F4FH@33958|Lactobacillaceae 91061|Bacilli IQ reductase gdh - 1.1.1.47 ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 - R01520,R01521 RC00066 ko00000,ko00001,ko01000 - - - adh_short_C2 NAGPHGKN_02466 568703.LGG_02188 6.91e-149 419.0 COG1835@1|root,COG1835@2|Bacteria,1UG9X@1239|Firmicutes,4IGYH@91061|Bacilli,3F8XZ@33958|Lactobacillaceae 91061|Bacilli I ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_5 NAGPHGKN_02467 568703.LGG_02187 7.25e-206 569.0 COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,4HB36@91061|Bacilli,3F4BW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter CcmA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_02468 568703.LGG_02186 1.13e-84 250.0 COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,4HKSY@91061|Bacilli,3F78Z@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR NAGPHGKN_02469 568703.LGG_02185 1.39e-278 764.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,3F3KA@33958|Lactobacillaceae 91061|Bacilli CP ABC-2 family transporter protein ysdA - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 NAGPHGKN_02470 568703.LGG_02184 1.04e-213 590.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,3F465@33958|Lactobacillaceae 91061|Bacilli S ABC transporter ysdB - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 NAGPHGKN_02471 568703.LGG_02183 1.35e-283 775.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase NAGPHGKN_02472 568703.LGG_02182 4.43e-224 618.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,3F4GC@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt NAGPHGKN_02473 568703.LGG_02181 4.09e-43 148.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F3JM@33958|Lactobacillaceae 91061|Bacilli H 1,4-dihydroxy-2-naphthoate menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA NAGPHGKN_02474 568703.LGG_02181 5.79e-132 379.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F3JM@33958|Lactobacillaceae 91061|Bacilli H 1,4-dihydroxy-2-naphthoate menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA NAGPHGKN_02475 568703.LGG_02180 4.35e-263 719.0 2EQYH@1|root,33II5@2|Bacteria,1VMH1@1239|Firmicutes,4HUIK@91061|Bacilli,3F5E7@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos NAGPHGKN_02476 1423816.BACQ01000077_gene2640 2.44e-06 52.0 COG1105@1|root,COG1105@2|Bacteria,1TR9H@1239|Firmicutes,4HAGR@91061|Bacilli 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily lacC - 2.7.1.144 ko:K00917 ko00052,ko01100,map00052,map01100 - R03236 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB NAGPHGKN_02477 568703.LGG_02175 0.0 1284.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,3F3NT@33958|Lactobacillaceae 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 NAGPHGKN_02478 568703.LGG_02174 4.41e-220 607.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer NAGPHGKN_02479 568703.LGG_02170 2.91e-223 628.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli 91061|Bacilli V domain protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 NAGPHGKN_02480 568703.LGG_02169 2.96e-132 375.0 COG1309@1|root,COG1309@2|Bacteria,1VZUX@1239|Firmicutes,4HY3K@91061|Bacilli,3F6GF@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N NAGPHGKN_02481 568703.LGG_02168 1.06e-185 516.0 COG0596@1|root,COG0596@2|Bacteria,1U3PB@1239|Firmicutes,4HB4W@91061|Bacilli,3F73K@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 NAGPHGKN_02482 568703.LGG_02167 3.3e-162 455.0 COG2013@1|root,COG2013@2|Bacteria,1TPN2@1239|Firmicutes,4HHYG@91061|Bacilli,3F4J7@33958|Lactobacillaceae 91061|Bacilli S Mitochondrial biogenesis AIM24 WQ51_05710 - - - - - - - - - - - AIM24 NAGPHGKN_02483 568703.LGG_02164 6.61e-277 757.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspC - 2.6.1.57 ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 M00024,M00025,M00034,M00040,M00525 R00694,R00734,R01731,R04467,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 NAGPHGKN_02484 568703.LGG_02163 6.32e-228 629.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HCIS@91061|Bacilli,3F4US@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhD - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C NAGPHGKN_02485 1423816.BACQ01000051_gene1954 1.16e-211 589.0 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC4N@91061|Bacilli,3FCB3@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase system, EIIC pfoSR - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 NAGPHGKN_02486 568703.LGG_02158 6.68e-89 261.0 2ESCD@1|root,33JX6@2|Bacteria,1VQB2@1239|Firmicutes,4HT0C@91061|Bacilli,3F9Y6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02487 568703.LGG_02157 3.05e-269 748.0 COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,4HA0C@91061|Bacilli,3F5TM@33958|Lactobacillaceae 91061|Bacilli S SPFH domain / Band 7 family floL - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot NAGPHGKN_02488 568703.LGG_02156 2.4e-312 852.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,3F48V@33958|Lactobacillaceae 91061|Bacilli E Belongs to the aspartokinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 NAGPHGKN_02489 568703.LGG_02155 7.93e-291 793.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,3F5BM@33958|Lactobacillaceae 91061|Bacilli E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 NAGPHGKN_02490 568703.LGG_02154 0.0 989.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,4H9R7@91061|Bacilli,3F3UF@33958|Lactobacillaceae 91061|Bacilli E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N NAGPHGKN_02491 568703.LGG_02153 8.12e-205 567.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,3F44T@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB - 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N NAGPHGKN_02492 568703.LGG_02152 0.0 864.0 COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,4HAB0@91061|Bacilli,3F3S7@33958|Lactobacillaceae 91061|Bacilli S ATP-grasp enzyme yxbA - 6.3.1.12 ko:K17810 - - - - ko00000,ko01000 - - - CPSase_L_D2,Dala_Dala_lig_C NAGPHGKN_02493 568703.LGG_02151 1.5e-95 279.0 COG0589@1|root,COG0589@2|Bacteria,1U62R@1239|Firmicutes,4IFRW@91061|Bacilli,3F6W5@33958|Lactobacillaceae 91061|Bacilli T Universal stress protein family usp1 - - - - - - - - - - - Usp NAGPHGKN_02494 568703.LGG_02149 9.41e-175 487.0 COG1489@1|root,COG1489@2|Bacteria,1V1GZ@1239|Firmicutes,4HCPN@91061|Bacilli,3F4KV@33958|Lactobacillaceae 91061|Bacilli S Belongs to the SfsA family sfsA - - ko:K06206 - - - - ko00000 - - - SfsA NAGPHGKN_02495 568703.LGG_02148 1.85e-284 778.0 COG4175@1|root,COG4175@2|Bacteria,1UHNE@1239|Firmicutes,4HA9P@91061|Bacilli,3FC38@33958|Lactobacillaceae 91061|Bacilli E glycine betaine gbuA - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS NAGPHGKN_02496 568703.LGG_02147 1.23e-190 530.0 COG4176@1|root,COG4176@2|Bacteria,1UHRI@1239|Firmicutes,4IS7D@91061|Bacilli,3F4W7@33958|Lactobacillaceae 91061|Bacilli E glycine betaine gbuB - - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 NAGPHGKN_02497 568703.LGG_02146 7.41e-211 582.0 COG2113@1|root,COG2113@2|Bacteria,1TP82@1239|Firmicutes,4H9MM@91061|Bacilli,3F4B3@33958|Lactobacillaceae 91061|Bacilli E glycine betaine gbuC - - ko:K02001,ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC NAGPHGKN_02498 568703.LGG_02145 0.0 1150.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family - - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N NAGPHGKN_02499 568703.LGG_02144 1.72e-76 229.0 COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,4HNK7@91061|Bacilli,3F4GH@33958|Lactobacillaceae 91061|Bacilli S Teichoic acid glycosylation protein gtcA2 - - - - - - - - - - - GtrA NAGPHGKN_02500 568703.LGG_02143 7.52e-80 241.0 COG3764@1|root,COG3764@2|Bacteria,1V4ZG@1239|Firmicutes,4HMUE@91061|Bacilli,3FBG7@33958|Lactobacillaceae 91061|Bacilli M Sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase NAGPHGKN_02501 568703.LGG_02143 1.57e-71 219.0 COG3764@1|root,COG3764@2|Bacteria,1V4ZG@1239|Firmicutes,4HMUE@91061|Bacilli,3FBG7@33958|Lactobacillaceae 91061|Bacilli M Sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase NAGPHGKN_02502 568703.LGG_02142 1.02e-238 658.0 COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,3F46E@33958|Lactobacillaceae 91061|Bacilli K AI-2E family transporter ydbI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport NAGPHGKN_02503 568703.LGG_02141 5.46e-258 707.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX - - - - - - - - - - - Beta-lactamase,SLH NAGPHGKN_02504 568703.LGG_02140 4.05e-201 562.0 COG4640@1|root,COG4640@2|Bacteria,1VIMB@1239|Firmicutes,4HP7R@91061|Bacilli,3F7Z9@33958|Lactobacillaceae 91061|Bacilli S zinc-ribbon domain - - - - - - - - - - - - zf-ribbon_3,zinc_ribbon_2 NAGPHGKN_02505 568703.LGG_02139 1.39e-40 134.0 2AWRG@1|root,31NNE@2|Bacteria,1U7XJ@1239|Firmicutes,4IHUY@91061|Bacilli,3FAAP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02506 568703.LGG_02138 1.15e-168 470.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,3F3SK@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 NAGPHGKN_02507 568703.LGG_02136 7.19e-113 323.0 COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,4HHQT@91061|Bacilli,3F4BS@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX NAGPHGKN_02508 568703.LGG_02134 5.56e-136 385.0 COG1846@1|root,COG1846@2|Bacteria,1VF51@1239|Firmicutes,4HM7R@91061|Bacilli,3F725@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR,MarR_2 NAGPHGKN_02509 568703.LGG_02132 9.23e-241 664.0 28USJ@1|root,2ZGWS@2|Bacteria,1W533@1239|Firmicutes,4I1UJ@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - zinc_ribbon_2 NAGPHGKN_02510 568703.LGG_02131 8.41e-236 649.0 COG0627@1|root,COG0627@2|Bacteria,1V856@1239|Firmicutes,4HVCY@91061|Bacilli,3F5Y5@33958|Lactobacillaceae 91061|Bacilli S Putative esterase - - - - - - - - - - - - Esterase NAGPHGKN_02511 1423734.JCM14202_162 3.25e-13 76.6 COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,3FBEE@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic tcaA - - ko:K21463 - - - - ko00000 - - - zf-ribbon_3,zinc_ribbon_2 NAGPHGKN_02512 568703.LGG_02129 8.12e-90 263.0 COG1846@1|root,COG1846@2|Bacteria,1VMZX@1239|Firmicutes,4HMTC@91061|Bacilli,3FBM2@33958|Lactobacillaceae 91061|Bacilli K MarR family - - - ko:K18909 - M00705 - - ko00000,ko00002,ko01504,ko03000 - - - MarR,MarR_2 NAGPHGKN_02513 568703.LGG_02128 9.17e-37 124.0 2AI31@1|root,318GU@2|Bacteria,1U7W4@1239|Firmicutes,4IHTI@91061|Bacilli,3FA8Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02514 568703.LGG_02127 2.45e-109 315.0 COG1846@1|root,COG1846@2|Bacteria,1VK0M@1239|Firmicutes,4IR3X@91061|Bacilli,3FBM5@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR_2 NAGPHGKN_02515 568703.LGG_02126 1.3e-79 237.0 COG0607@1|root,COG0607@2|Bacteria,1VVR4@1239|Firmicutes,4HWD0@91061|Bacilli,3FBBI@33958|Lactobacillaceae 91061|Bacilli P Rhodanese-like domain - - - - - - - - - - - - Rhodanese NAGPHGKN_02516 568703.LGG_02124 1.61e-117 345.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4H9TR@91061|Bacilli,3F4VF@33958|Lactobacillaceae 91061|Bacilli C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH NAGPHGKN_02517 568703.LGG_02124 5.21e-145 416.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4H9TR@91061|Bacilli,3F4VF@33958|Lactobacillaceae 91061|Bacilli C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH NAGPHGKN_02518 568703.LGG_02123 4.22e-245 672.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 NAGPHGKN_02519 568703.LGG_02122 7.93e-94 274.0 COG0764@1|root,COG0764@2|Bacteria,1V3UN@1239|Firmicutes,4HHYD@91061|Bacilli,3F77T@33958|Lactobacillaceae 91061|Bacilli I FabA-like domain - - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA NAGPHGKN_02520 1423732.BALS01000016_gene1714 1.41e-98 286.0 COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,4IR3W@91061|Bacilli,3FC7M@33958|Lactobacillaceae 91061|Bacilli K Winged helix DNA-binding domain - - - - - - - - - - - - MarR NAGPHGKN_02521 568703.LGG_02120 2.03e-223 616.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,3F3XP@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C NAGPHGKN_02522 568703.LGG_02119 5.61e-45 145.0 COG0236@1|root,COG0236@2|Bacteria,1VGIY@1239|Firmicutes,4HP0V@91061|Bacilli,3F7ZJ@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding NAGPHGKN_02523 568703.LGG_02118 3.91e-220 608.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,3F4PC@33958|Lactobacillaceae 91061|Bacilli S Nitronate monooxygenase fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO NAGPHGKN_02524 568703.LGG_02117 1.25e-211 585.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,3F3W9@33958|Lactobacillaceae 91061|Bacilli I Malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 NAGPHGKN_02525 568703.LGG_02116 2.03e-164 461.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,3F4RI@33958|Lactobacillaceae 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 NAGPHGKN_02526 568703.LGG_02115 4.03e-283 775.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,3F51H@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt NAGPHGKN_02527 568703.LGG_02114 2.52e-87 258.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,3F7M1@33958|Lactobacillaceae 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl NAGPHGKN_02528 568703.LGG_02113 4.77e-100 290.0 COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli,3F5EE@33958|Lactobacillaceae 91061|Bacilli I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA NAGPHGKN_02529 568703.LGG_02112 0.0 900.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,3F3PT@33958|Lactobacillaceae 91061|Bacilli I Acetyl-CoA carboxylase biotin carboxylase subunit accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 NAGPHGKN_02530 568703.LGG_02111 2.72e-197 546.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,3F3T6@33958|Lactobacillaceae 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans NAGPHGKN_02531 568703.LGG_02110 4.11e-141 400.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,3F496@33958|Lactobacillaceae 91061|Bacilli I alpha subunit accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA NAGPHGKN_02532 568703.LGG_02109 1.54e-294 802.0 COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,4HDKI@91061|Bacilli,3F3PA@33958|Lactobacillaceae 91061|Bacilli M cyclopropane-fatty-acyl-phospholipid synthase cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS NAGPHGKN_02533 568703.LGG_02108 6.17e-203 562.0 COG0702@1|root,COG0702@2|Bacteria,1UY7W@1239|Firmicutes,4HDIS@91061|Bacilli,3F4M7@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10,NmrA NAGPHGKN_02535 568703.LGG_02107 0.0 1023.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,3F4UD@33958|Lactobacillaceae 91061|Bacilli G invertase scrB - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N NAGPHGKN_02536 568703.LGG_02106 4.42e-225 622.0 COG1609@1|root,COG1609@2|Bacteria,1TRHK@1239|Firmicutes,4HB9P@91061|Bacilli,3F5FI@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding proteins and sugar binding domain of LacI family purR2 - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 NAGPHGKN_02537 568703.LGG_02105 0.0 1143.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459,Malt_amylase_C NAGPHGKN_02538 1423732.BALS01000016_gene1697 0.0 1161.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts26BCA - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NAGPHGKN_02539 568703.LGG_02102 0.0 1406.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,3F3Y3@33958|Lactobacillaceae 91061|Bacilli V domain protein pip - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 NAGPHGKN_02540 568703.LGG_02101 2.87e-270 741.0 2DSXT@1|root,32UTZ@2|Bacteria,1VRUF@1239|Firmicutes,4HTM0@91061|Bacilli,3FB9G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF998 NAGPHGKN_02541 568703.LGG_02100 1.16e-135 384.0 2BHSC@1|root,32BVX@2|Bacteria,1TURM@1239|Firmicutes,4HYSA@91061|Bacilli,3F81M@33958|Lactobacillaceae 91061|Bacilli S Putative inner membrane protein (DUF1819) - - - - - - - - - - - - DUF1819 NAGPHGKN_02542 568703.LGG_02099 6.14e-86 255.0 28KCG@1|root,2Z9ZE@2|Bacteria,1V4X3@1239|Firmicutes,4IRD7@91061|Bacilli,3F6NV@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1788) - - - - - - - - - - - - DUF1788 NAGPHGKN_02543 568703.LGG_02098 0.0 2346.0 COG1293@1|root,COG1293@2|Bacteria,1TR5Q@1239|Firmicutes,4H9MP@91061|Bacilli,3F5TF@33958|Lactobacillaceae 91061|Bacilli K RNA-binding protein homologous to eukaryotic snRNP - - - - - - - - - - - - KAP_NTPase NAGPHGKN_02544 568703.LGG_02097 5.07e-116 365.0 COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1TQ39@1239|Firmicutes,4HA3J@91061|Bacilli,3F5ED@33958|Lactobacillaceae 91061|Bacilli V Eco57I restriction-modification methylase - - - - - - - - - - - - Eco57I,N6_Mtase NAGPHGKN_02545 568703.LGG_02083 1.46e-134 382.0 2AGPG@1|root,316X2@2|Bacteria,1U7BQ@1239|Firmicutes,4IH6V@91061|Bacilli,3F9AE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02546 568703.LGG_02082 0.0 1681.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,3F5WR@33958|Lactobacillaceae 91061|Bacilli L Helix-hairpin-helix containing domain - - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,UvrD_C_2 NAGPHGKN_02547 568703.LGG_02081 6.82e-170 475.0 COG3860@1|root,COG3860@2|Bacteria,1TPHH@1239|Firmicutes,4HCHE@91061|Bacilli,3F56B@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2087) - - - - - - - - - - - - DUF2087,GerE NAGPHGKN_02548 568703.LGG_02080 4.11e-171 478.0 COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,4HFN2@91061|Bacilli,3F4KR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0246 family XK27_08125 - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD NAGPHGKN_02549 568703.LGG_02079 0.0 1506.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,3F3RU@33958|Lactobacillaceae 91061|Bacilli G alpha-galactosidase galA - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase NAGPHGKN_02550 568703.LGG_02078 0.0 924.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F4VG@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane chbC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC NAGPHGKN_02551 568703.LGG_02076 1.92e-92 270.0 2DQNY@1|root,337UX@2|Bacteria,1VEZ0@1239|Firmicutes,4HPE2@91061|Bacilli,3F875@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF3284) - - - - - - - - - - - - DUF3284 NAGPHGKN_02552 568703.LGG_02075 6.25e-269 735.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4H9V2@91061|Bacilli,3F4FK@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) ybhE - - ko:K09963 - - - - ko00000 - - - DUF871 NAGPHGKN_02553 568703.LGG_02074 6.5e-71 214.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,3FA0Y@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit - - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA NAGPHGKN_02554 568703.LGG_02073 1.32e-131 373.0 2AYWY@1|root,30B2F@2|Bacteria,1U7F5@1239|Firmicutes,4IHB5@91061|Bacilli,3F9II@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02555 568703.LGG_02071 3.29e-188 522.0 COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli,3F4GX@33958|Lactobacillaceae 91061|Bacilli C Cysteine-rich domain lutA - - ko:K18928 - - - - ko00000 - - - CCG NAGPHGKN_02556 568703.LGG_02070 0.0 999.0 COG1139@1|root,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,3F4IV@33958|Lactobacillaceae 91061|Bacilli C 4Fe-4S dicluster domain lutB - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_8,LUD_dom NAGPHGKN_02557 568703.LGG_02069 2.6e-168 470.0 COG1556@1|root,COG1556@2|Bacteria,1UZAK@1239|Firmicutes,4HH3R@91061|Bacilli,3F4UV@33958|Lactobacillaceae 91061|Bacilli S LUD domain lutC - - ko:K00782 - - - - ko00000 - - - LUD_dom NAGPHGKN_02558 568703.LGG_02068 5.82e-130 369.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F4EW@33958|Lactobacillaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C NAGPHGKN_02559 568703.LGG_02067 6.86e-196 555.0 COG0477@1|root,COG2814@2|Bacteria,1VSAB@1239|Firmicutes,4HECQ@91061|Bacilli,3FCCN@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 NAGPHGKN_02560 568703.LGG_02067 1.97e-61 201.0 COG0477@1|root,COG2814@2|Bacteria,1VSAB@1239|Firmicutes,4HECQ@91061|Bacilli,3FCCN@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 NAGPHGKN_02561 568703.LGG_02066 0.0 1059.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 NAGPHGKN_02562 568703.LGG_02065 1.15e-207 575.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,3F42T@33958|Lactobacillaceae 91061|Bacilli P ABC-type dipeptide oligopeptide nickel transport systems, permease components oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 NAGPHGKN_02563 568703.LGG_02064 3.36e-224 619.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,3F3W3@33958|Lactobacillaceae 91061|Bacilli EP ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N NAGPHGKN_02564 568703.LGG_02063 8.73e-150 429.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3F41T@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD - - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY NAGPHGKN_02565 568703.LGG_02063 8.13e-61 195.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3F41T@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD - - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY NAGPHGKN_02566 568703.LGG_02062 7.74e-232 638.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,3F4GM@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppF - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY NAGPHGKN_02567 568703.LGG_02061 8.42e-149 419.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F4IS@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpm5 - - - - - - - - - - - His_Phos_1 NAGPHGKN_02568 568703.LGG_02060 3.39e-64 196.0 COG1396@1|root,COG1396@2|Bacteria,1V3D7@1239|Firmicutes,4IGD5@91061|Bacilli,3F83A@33958|Lactobacillaceae 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 NAGPHGKN_02569 568703.LGG_02059 8.55e-49 155.0 2E68Y@1|root,330X0@2|Bacteria,1VFBF@1239|Firmicutes,4HP3V@91061|Bacilli,3F810@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2829) XK27_01315 - - - - - - - - - - - DUF2829 NAGPHGKN_02570 568703.LGG_02058 1.09e-161 453.0 COG1028@1|root,COG1028@2|Bacteria,1U8IC@1239|Firmicutes,4HC26@91061|Bacilli,3F4X3@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 NAGPHGKN_02571 568703.LGG_02057 5.97e-106 306.0 COG4708@1|root,COG4708@2|Bacteria,1V22G@1239|Firmicutes,4HGG2@91061|Bacilli,3F6CG@33958|Lactobacillaceae 91061|Bacilli S QueT transporter ccl GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - QueT NAGPHGKN_02572 568703.LGG_02054 1.38e-166 466.0 COG2755@1|root,COG2755@2|Bacteria,1UI5G@1239|Firmicutes,4ISEF@91061|Bacilli,3F652@33958|Lactobacillaceae 91061|Bacilli E lipolytic protein G-D-S-L family - - - - - - - - - - - - - NAGPHGKN_02573 568703.LGG_02053 4.63e-139 402.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,3F4M5@33958|Lactobacillaceae 91061|Bacilli M biosynthesis protein epsB - - - - - - - - - - - GNVR,Wzz NAGPHGKN_02574 568703.LGG_02052 5.97e-136 389.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,3F4BM@33958|Lactobacillaceae 91061|Bacilli D Capsular exopolysaccharide family ywqD - - - - - - - - - - - AAA_31,ParA NAGPHGKN_02575 665950.HMPREF1025_00987 1.43e-18 92.8 COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,24H9J@186801|Clostridia,27NU9@186928|unclassified Lachnospiraceae 186801|Clostridia M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 NAGPHGKN_02577 457396.CSBG_00444 8.46e-18 90.5 COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,24H9J@186801|Clostridia,36UU1@31979|Clostridiaceae 186801|Clostridia S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 NAGPHGKN_02578 1158610.UC3_00550 2.78e-76 246.0 COG0438@1|root,COG0438@2|Bacteria,1UZ0I@1239|Firmicutes,4HC23@91061|Bacilli,4B3HR@81852|Enterococcaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_A_1,Glyco_transf_4,Glycos_transf_1 NAGPHGKN_02579 1203076.CAKF01000015_gene1665 4.87e-32 129.0 COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HCW0@91061|Bacilli,3FBRJ@33958|Lactobacillaceae 91061|Bacilli S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 NAGPHGKN_02580 1423806.JCM15457_1665 6.3e-33 132.0 COG5039@1|root,COG5039@2|Bacteria,1V5MK@1239|Firmicutes,4HB4G@91061|Bacilli,3F5ZU@33958|Lactobacillaceae 91061|Bacilli GM Polysaccharide pyruvyl transferase - - - ko:K19426 - - - - ko00000,ko01000 - - - PS_pyruv_trans NAGPHGKN_02581 866895.HBHAL_1978 3.86e-85 279.0 COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,4HCW6@91061|Bacilli 91061|Bacilli S Psort location CytoplasmicMembrane, score cps2I - - - - - - - - - - - Polysacc_synt NAGPHGKN_02582 568703.LGG_02048 3.15e-42 147.0 COG1442@1|root,COG1442@2|Bacteria,1U6EG@1239|Firmicutes,4HG4F@91061|Bacilli,3F539@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF4422) cps3J - - - - - - - - - - - DUF4422 NAGPHGKN_02584 568703.LGG_02043 2.57e-104 307.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HEU3@91061|Bacilli,3FBD1@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase rfbP - - - - - - - - - - - Bac_transf NAGPHGKN_02585 568703.LGG_01962 1.39e-196 554.0 COG4974@1|root,COG4974@2|Bacteria,1TQST@1239|Firmicutes,4HPQC@91061|Bacilli,3F47D@33958|Lactobacillaceae 91061|Bacilli L Transposase IS66 family - - - ko:K07484 - - - - ko00000 - - - DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66 NAGPHGKN_02586 568703.LGG_01962 1.22e-81 255.0 COG4974@1|root,COG4974@2|Bacteria,1TQST@1239|Firmicutes,4HPQC@91061|Bacilli,3F47D@33958|Lactobacillaceae 91061|Bacilli L Transposase IS66 family - - - ko:K07484 - - - - ko00000 - - - DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66 NAGPHGKN_02587 543734.LCABL_04090 5.68e-76 227.0 COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,4HWVD@91061|Bacilli,3FB8I@33958|Lactobacillaceae 91061|Bacilli L IS66 Orf2 like protein - - - ko:K07484 - - - - ko00000 - - - TnpB_IS66 NAGPHGKN_02588 568703.LGG_01960 9.81e-32 111.0 2DKT5@1|root,30AQC@2|Bacteria,1U6ZC@1239|Firmicutes,4IGTM@91061|Bacilli,3F8RM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02589 568703.LGG_02037 6.35e-200 555.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr NAGPHGKN_02590 568703.LGG_02036 1.09e-174 488.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,3F3RT@33958|Lactobacillaceae 91061|Bacilli GM PHP domain protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - NAGPHGKN_02591 1423816.BACQ01000050_gene1849 1.95e-197 555.0 COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,4HB5F@91061|Bacilli,3F52G@33958|Lactobacillaceae 91061|Bacilli M UDP-galactopyranose mutase glf - 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - GLF,NAD_binding_8 NAGPHGKN_02592 568703.LGG_02035 0.0 1391.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F43D@33958|Lactobacillaceae 91061|Bacilli O associated with various cellular activities clpE - - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR NAGPHGKN_02593 568703.LGG_02034 2.27e-85 252.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F9SP@33958|Lactobacillaceae 91061|Bacilli P ArsC family spx2 - - ko:K16509 - - - - ko00000 - - - ArsC NAGPHGKN_02594 568703.LGG_02032 6.8e-222 625.0 COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,4HBAN@91061|Bacilli,3F4MG@33958|Lactobacillaceae 91061|Bacilli G phosphatase activity fbp - 3.1.3.11 ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_2 NAGPHGKN_02595 568703.LGG_02032 9.86e-231 647.0 COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,4HBAN@91061|Bacilli,3F4MG@33958|Lactobacillaceae 91061|Bacilli G phosphatase activity fbp - 3.1.3.11 ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_2 NAGPHGKN_02596 568703.LGG_02031 3.72e-186 519.0 COG1284@1|root,COG1284@2|Bacteria,1TWZ5@1239|Firmicutes,4HD8R@91061|Bacilli,3F54A@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - DUF2179,YitT_membrane NAGPHGKN_02597 568703.LGG_02030 1.8e-180 506.0 COG3764@1|root,COG3764@2|Bacteria,1VXZD@1239|Firmicutes,4HXV4@91061|Bacilli,3F9NX@33958|Lactobacillaceae 91061|Bacilli M Sortase family - - - - - - - - - - - - DUF5011,Sortase NAGPHGKN_02598 568703.LGG_02028 1.02e-260 712.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli,3F4BD@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 NAGPHGKN_02599 568703.LGG_02027 0.0 1451.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli,3F4KT@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 NAGPHGKN_02600 568703.LGG_02026 1.51e-254 701.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,3F4IA@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase NAGPHGKN_02601 568703.LGG_02025 3.02e-258 710.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli,3F58E@33958|Lactobacillaceae 91061|Bacilli G Nucleotidyl transferase glgD - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase NAGPHGKN_02602 568703.LGG_02024 0.0 986.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,3F3PP@33958|Lactobacillaceae 91061|Bacilli F Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 NAGPHGKN_02604 568703.LGG_02023 0.0 1595.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,3F4Z1@33958|Lactobacillaceae 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase NAGPHGKN_02605 568703.LGG_02022 0.0 1231.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,3F41N@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family malZ - 3.2.1.20,3.2.1.41 ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 - R00028,R00801,R00802,R02111,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - CBM48,GH13,GH31 - Alpha-amylase,Alpha-amylase_N NAGPHGKN_02606 568703.LGG_02021 6.3e-222 612.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HHVC@91061|Bacilli,3F3QR@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE NAGPHGKN_02607 568703.LGG_02020 1.38e-71 215.0 COG0640@1|root,COG0640@2|Bacteria,1VFY4@1239|Firmicutes,4HP5T@91061|Bacilli,3F8JS@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5 NAGPHGKN_02608 1423816.BACQ01000049_gene1827 5.22e-207 574.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer NAGPHGKN_02609 568703.LGG_02017 6.53e-309 841.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,3F48J@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b NAGPHGKN_02610 568703.LGG_02016 8.57e-203 571.0 COG0791@1|root,COG0791@2|Bacteria,1UVYK@1239|Firmicutes,4HDAX@91061|Bacilli,3F5PQ@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family spl - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 NAGPHGKN_02611 568703.LGG_02015 9.55e-88 258.0 COG0454@1|root,COG0454@2|Bacteria,1VA4N@1239|Firmicutes,4HIIX@91061|Bacilli,3F7MY@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 NAGPHGKN_02612 568703.LGG_02014 8.86e-145 407.0 COG0194@1|root,COG0194@2|Bacteria,1V8PW@1239|Firmicutes,4HJCB@91061|Bacilli,3F6N3@33958|Lactobacillaceae 91061|Bacilli F Guanylate kinase gmk2 - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin NAGPHGKN_02613 568703.LGG_02013 1.1e-13 63.9 29QNJ@1|root,30BN7@2|Bacteria,1U8CS@1239|Firmicutes,4IIAR@91061|Bacilli,3FAUD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02614 568703.LGG_02012 1.93e-110 317.0 COG0735@1|root,COG0735@2|Bacteria,1V6RI@1239|Firmicutes,4HIGM@91061|Bacilli,3F6W3@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Fur family zur - - ko:K02076,ko:K03711 - - - - ko00000,ko03000 - - - FUR NAGPHGKN_02615 1329250.WOSG25_060140 0.000417 45.8 2EQI3@1|root,33I43@2|Bacteria,1VN2E@1239|Firmicutes,4HR4S@91061|Bacilli,4AY6Z@81850|Leuconostocaceae 91061|Bacilli - - - - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - - NAGPHGKN_02616 568703.LGG_02010 1.95e-221 611.0 2C6F0@1|root,32RH8@2|Bacteria,1V7ET@1239|Firmicutes,4HJDI@91061|Bacilli,3F4UC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02617 568703.LGG_02009 1.05e-172 482.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - - ko:K10041 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran NAGPHGKN_02619 568703.LGG_02008 5.86e-189 525.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli,3F4GG@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein glnH - - ko:K10039 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 NAGPHGKN_02620 568703.LGG_02007 1.18e-140 398.0 COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HFBH@91061|Bacilli,3F3XW@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnM GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 NAGPHGKN_02621 568703.LGG_02006 7.92e-142 402.0 COG0765@1|root,COG0765@2|Bacteria,1UJM4@1239|Firmicutes,4HBAS@91061|Bacilli,3F3WJ@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 NAGPHGKN_02622 568703.LGG_02005 4.63e-225 620.0 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,3F5GY@33958|Lactobacillaceae 91061|Bacilli M RmlD substrate binding domain cps2D - 5.1.3.2,5.1.3.25 ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 M00361,M00362,M00632 R00291,R02984,R10279 RC00289 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS00780 Epimerase,GDP_Man_Dehyd NAGPHGKN_02623 1423816.BACQ01000049_gene1814 7.75e-146 414.0 COG0463@1|root,COG0463@2|Bacteria,1TSFF@1239|Firmicutes,4HCPR@91061|Bacilli 91061|Bacilli M Glycosyltransferase like family 2 tuaG - - ko:K16698 - - - - ko00000,ko01000,ko01003 - GT2 - Glycos_transf_2 NAGPHGKN_02624 1423732.BALS01000012_gene1489 1.09e-170 477.0 COG3774@1|root,COG3774@2|Bacteria,1V9J7@1239|Firmicutes,4HIAM@91061|Bacilli,3F4U2@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase sugar-binding region containing DXD motif - - - - - - - - - - - - Caps_synth,Gly_transf_sug NAGPHGKN_02625 1423732.BALS01000012_gene1488 0.0 877.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HB15@91061|Bacilli,3F5WM@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase cps2E - - - - - - - - - - - Bac_transf,CoA_binding_3 NAGPHGKN_02626 1423732.BALS01000012_gene1487 1.41e-115 341.0 2BVD0@1|root,32QT1@2|Bacteria,1V3YR@1239|Firmicutes,4HIBT@91061|Bacilli,3FBAX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02627 1423816.BACQ01000049_gene1810 4.48e-254 699.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,3F3KQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 NAGPHGKN_02628 1423816.BACQ01000049_gene1809 8.66e-202 563.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,3F3X7@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 2 ykoT - - - - - - - - - - - Glycos_transf_2 NAGPHGKN_02629 1423816.BACQ01000049_gene1807 3.19e-142 410.0 COG3936@1|root,COG3936@2|Bacteria,1VKG7@1239|Firmicutes 1239|Firmicutes M Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 NAGPHGKN_02630 1423816.BACQ01000049_gene1806 1.42e-224 632.0 COG1807@1|root,COG1807@2|Bacteria,1V114@1239|Firmicutes,4HB64@91061|Bacilli,3F5S6@33958|Lactobacillaceae 91061|Bacilli M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 NAGPHGKN_02631 1423732.BALS01000012_gene1482 0.0 1066.0 COG3757@1|root,COG3757@2|Bacteria,1UJED@1239|Firmicutes,4IV6A@91061|Bacilli,3FC2G@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25,SH3_8 NAGPHGKN_02632 1423816.BACQ01000049_gene1804 1.03e-275 770.0 COG4485@1|root,COG4485@2|Bacteria,1UZCF@1239|Firmicutes,4HDPY@91061|Bacilli,3F48H@33958|Lactobacillaceae 91061|Bacilli S Bacterial membrane protein, YfhO - - - - - - - - - - - - - NAGPHGKN_02633 1423816.BACQ01000049_gene1802 5.35e-151 435.0 COG0463@1|root,COG0463@2|Bacteria,1W2XN@1239|Firmicutes,4I0ZS@91061|Bacilli,3FAFU@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 NAGPHGKN_02634 1423816.BACQ01000049_gene1801 2.61e-252 695.0 COG0438@1|root,COG0438@2|Bacteria,1V2GM@1239|Firmicutes,4IQA6@91061|Bacilli 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 NAGPHGKN_02635 1423732.BALS01000084_gene2007 6.29e-314 858.0 COG2244@1|root,COG2244@2|Bacteria,1V21R@1239|Firmicutes 1239|Firmicutes S polysaccharide biosynthetic process - - - - - - - - - - - - - NAGPHGKN_02636 1423732.BALS01000084_gene2008 1.45e-126 364.0 COG3944@1|root,COG3944@2|Bacteria 2|Bacteria M capsule polysaccharide biosynthetic process ywqC - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - GNVR,Wzz NAGPHGKN_02637 1423816.BACQ01000048_gene1797 3.25e-107 313.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,3F4BM@33958|Lactobacillaceae 91061|Bacilli D Capsular exopolysaccharide family - - - - - - - - - - - - AAA_31 NAGPHGKN_02638 1423732.BALS01000084_gene2010 1.7e-221 614.0 2DR4Q@1|root,33A5I@2|Bacteria,1VM59@1239|Firmicutes,4HT66@91061|Bacilli 91061|Bacilli S EpsG family - - - - - - - - - - - - EpsG NAGPHGKN_02639 1423816.BACQ01000047_gene1795 0.0 1195.0 COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,4HBY6@91061|Bacilli,3F3NY@33958|Lactobacillaceae 91061|Bacilli M Sulfatase - - - - - - - - - - - - Sulfatase NAGPHGKN_02640 1423816.BACQ01000047_gene1794 1.33e-140 407.0 COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HHQN@91061|Bacilli,3FC25@33958|Lactobacillaceae 91061|Bacilli G Polysaccharide deacetylase nodB3 - - - - - - - - - - - Polysacc_deac_1 NAGPHGKN_02641 568703.LGG_01989 1.53e-302 826.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,3F4B2@33958|Lactobacillaceae 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 NAGPHGKN_02642 568703.LGG_01988 5.19e-207 575.0 COG1597@1|root,COG1597@2|Bacteria,1V4PN@1239|Firmicutes,4HHJP@91061|Bacilli,3F3Z6@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat NAGPHGKN_02643 568703.LGG_01987 0.0 1100.0 COG0531@1|root,COG0531@2|Bacteria,1VTQI@1239|Firmicutes,4HU7Y@91061|Bacilli,3FBET@33958|Lactobacillaceae 91061|Bacilli E Amino Acid - - - - - - - - - - - - AA_permease_2 NAGPHGKN_02644 568703.LGG_01986 5.4e-174 486.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3F3MG@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein cysA - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_02645 568703.LGG_01985 0.0 1105.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4HAZG@91061|Bacilli,3F45H@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX NAGPHGKN_02646 568703.LGG_01984 1.69e-218 602.0 COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,4H9QT@91061|Bacilli,3F4WZ@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde rhaD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.2.19 ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01785,R02263 RC00438,RC00599,RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II NAGPHGKN_02647 568703.LGG_01983 4.02e-165 461.0 COG0406@1|root,COG0406@2|Bacteria,1TQWQ@1239|Firmicutes,4HF2N@91061|Bacilli,3F524@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpm2 - - - - - - - - - - - His_Phos_1 NAGPHGKN_02648 568703.LGG_01982 1.02e-234 645.0 COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli,3F4VU@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase NAGPHGKN_02649 568703.LGG_01981 1.31e-304 833.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp NAGPHGKN_02650 568703.LGG_01980 9.11e-106 305.0 2C3KP@1|root,2Z802@2|Bacteria,1TQD1@1239|Firmicutes,4HBGA@91061|Bacilli,3F71P@33958|Lactobacillaceae 91061|Bacilli S Phage tail protein yjhE - - - - - - - - - - - - NAGPHGKN_02651 568703.LGG_01979 3.98e-230 632.0 COG2267@1|root,COG2267@2|Bacteria,1UEDT@1239|Firmicutes,4HF61@91061|Bacilli,3F47H@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepR - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 NAGPHGKN_02652 568703.LGG_01978 0.0 1117.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,4H9Q5@91061|Bacilli,3F4AZ@33958|Lactobacillaceae 91061|Bacilli P TrkA C-terminal domain protein yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N NAGPHGKN_02653 568703.LGG_01977 7.41e-37 124.0 2AX78@1|root,31P5Y@2|Bacteria,1U818@1239|Firmicutes,4IHYP@91061|Bacilli,3FAEP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02654 568703.LGG_02307 7.5e-190 530.0 COG4939@1|root,COG4939@2|Bacteria,1V2YY@1239|Firmicutes,4HGMF@91061|Bacilli,3FBKH@33958|Lactobacillaceae 91061|Bacilli S FMN_bind cad - - ko:K20379 ko02024,map02024 - - - ko00000,ko00001 - - - FMN_bind NAGPHGKN_02655 568703.LGG_02308 0.0 1248.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,3F4N1@33958|Lactobacillaceae 91061|Bacilli C NADH dehydrogenase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DoxX,Pyr_redox_2 NAGPHGKN_02656 568703.LGG_02309 2.87e-106 306.0 COG5341@1|root,COG5341@2|Bacteria,1VCR8@1239|Firmicutes,4HMR5@91061|Bacilli,3F7R1@33958|Lactobacillaceae 91061|Bacilli S NusG domain II - - - - - - - - - - - - NusG_II NAGPHGKN_02657 568703.LGG_02310 7.23e-128 364.0 COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,4HG1H@91061|Bacilli,3F3R8@33958|Lactobacillaceae 91061|Bacilli S Heptaprenyl diphosphate synthase component I hepA - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - Hpre_diP_synt_I NAGPHGKN_02658 568703.LGG_02311 9.42e-232 638.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,3F4GC@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 - R09245,R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt NAGPHGKN_02659 568703.LGG_02312 9.18e-105 303.0 2AVBI@1|root,31M2U@2|Bacteria,1U7J9@1239|Firmicutes,4IHG6@91061|Bacilli,3F9T2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02660 568703.LGG_02313 3.41e-187 520.0 COG0639@1|root,COG0639@2|Bacteria,1UZK9@1239|Firmicutes,4HG1F@91061|Bacilli,3F5JR@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase superfamily domain prpA3 - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - Metallophos_2 NAGPHGKN_02661 568703.LGG_02315 5.81e-125 356.0 2C156@1|root,31XDV@2|Bacteria,1W25B@1239|Firmicutes,4I11R@91061|Bacilli,3FAM2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02662 568703.LGG_02316 1.29e-202 561.0 2AGH5@1|root,316PQ@2|Bacteria,1U79G@1239|Firmicutes,4IH4B@91061|Bacilli,3F95I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02663 568703.LGG_02318 3.67e-196 545.0 COG1131@1|root,COG1131@2|Bacteria,1TQA2@1239|Firmicutes,4HEU0@91061|Bacilli,3FC3N@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_02664 568703.LGG_02319 2.02e-273 751.0 28MM7@1|root,2ZAX4@2|Bacteria,1TT1Z@1239|Firmicutes,4HDYX@91061|Bacilli,3F45B@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02665 568703.LGG_02320 4.05e-247 681.0 28MJI@1|root,2ZAW0@2|Bacteria,1UZZX@1239|Firmicutes,4HCUA@91061|Bacilli,3F5KU@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - NAGPHGKN_02666 568703.LGG_02321 2.58e-155 436.0 COG2085@1|root,COG2085@2|Bacteria,1UXZM@1239|Firmicutes,4HDRH@91061|Bacilli,3FB9A@33958|Lactobacillaceae 91061|Bacilli S Rossmann-like domain - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored NAGPHGKN_02667 568703.LGG_02322 3.64e-249 684.0 COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,3F4KZ@33958|Lactobacillaceae 91061|Bacilli C Luciferase-like monooxygenase XK27_00915 - - - - - - - - - - - Bac_luciferase NAGPHGKN_02668 568703.LGG_02323 1.45e-126 360.0 COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli,3F5KC@33958|Lactobacillaceae 91061|Bacilli S YacP-like NYN domain yacP - - ko:K06962 - - - - ko00000 - - - NYN_YacP NAGPHGKN_02669 568703.LGG_02324 2.6e-185 515.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,3F3TD@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind NAGPHGKN_02670 568703.LGG_02325 2.3e-96 280.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,3F6HS@33958|Lactobacillaceae 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 NAGPHGKN_02671 568703.LGG_02326 0.0 944.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,3F4K7@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g NAGPHGKN_02672 1423816.BACQ01000055_gene2124 4.31e-312 853.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,3F4AD@33958|Lactobacillaceae 91061|Bacilli C FAD linked oxidases, C-terminal domain loxD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 NAGPHGKN_02673 568703.LGG_02330 5.16e-127 362.0 29Q7Y@1|root,30B6Z@2|Bacteria,1U7NE@1239|Firmicutes,4IHJP@91061|Bacilli,3F9Y4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02675 568703.LGG_02332 1.42e-187 531.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,3F3PR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c NAGPHGKN_02676 568703.LGG_02332 3.64e-138 402.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,3F3PR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c NAGPHGKN_02677 568703.LGG_02333 1.93e-179 501.0 COG4377@1|root,COG4377@2|Bacteria,1V3UF@1239|Firmicutes,4HEYB@91061|Bacilli,3F7XI@33958|Lactobacillaceae 91061|Bacilli S Putative membrane peptidase family (DUF2324) yhfC - - - - - - - - - - - DUF2324 NAGPHGKN_02678 568703.LGG_02334 2.65e-224 620.0 COG4194@1|root,COG4194@2|Bacteria,1UY2R@1239|Firmicutes,4HEEQ@91061|Bacilli,3F7N8@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - DUF1648 NAGPHGKN_02679 568703.LGG_02335 3.54e-82 243.0 COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,4HJDB@91061|Bacilli,3F8MP@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - GntR NAGPHGKN_02680 568703.LGG_02336 0.0 1000.0 COG1132@1|root,COG1132@2|Bacteria,1UYYQ@1239|Firmicutes,4HWP7@91061|Bacilli,3F5DU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran NAGPHGKN_02681 568703.LGG_02337 6.07e-292 800.0 COG4932@1|root,COG4932@2|Bacteria,1UWF2@1239|Firmicutes,4HGU0@91061|Bacilli,3F6D1@33958|Lactobacillaceae 91061|Bacilli M MucBP domain inlJ - - - - - - - - - - - DUF285,Gram_pos_anchor,MucBP NAGPHGKN_02682 543734.LCABL_25050 6.42e-88 268.0 COG1277@1|root,COG1277@2|Bacteria,1V1GX@1239|Firmicutes,4HG2P@91061|Bacilli,3F52P@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4 NAGPHGKN_02683 543734.LCABL_25060 1.39e-120 354.0 COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,3F3YW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_02684 543734.LCABL_25070 1.12e-138 400.0 COG1396@1|root,COG1396@2|Bacteria,1U7HF@1239|Firmicutes,4IHE2@91061|Bacilli,3F9PR@33958|Lactobacillaceae 91061|Bacilli K sequence-specific DNA binding - - - - - - - - - - - - - NAGPHGKN_02685 568703.LGG_02339 1.22e-93 282.0 COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,3F46T@33958|Lactobacillaceae 91061|Bacilli S domain protein yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - TRAM NAGPHGKN_02686 568703.LGG_02339 5.62e-145 416.0 COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,3F46T@33958|Lactobacillaceae 91061|Bacilli S domain protein yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - TRAM NAGPHGKN_02687 568703.LGG_02340 1.18e-50 171.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,3F3W8@33958|Lactobacillaceae 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI NAGPHGKN_02688 568703.LGG_02340 9.39e-189 532.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,3F3W8@33958|Lactobacillaceae 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI NAGPHGKN_02689 568703.LGG_02340 1.84e-38 139.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,3F3W8@33958|Lactobacillaceae 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI NAGPHGKN_02690 568703.LGG_02341 4.49e-130 369.0 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli,3FB45@33958|Lactobacillaceae 91061|Bacilli F dUTPase dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase NAGPHGKN_02691 568703.LGG_02343 2.37e-65 198.0 COG2388@1|root,COG2388@2|Bacteria,1VEEX@1239|Firmicutes,4HNR2@91061|Bacilli,3F80F@33958|Lactobacillaceae 91061|Bacilli S GCN5-related N-acetyl-transferase yjdJ - - ko:K06975 - - - - ko00000 - - - Acetyltransf_CG NAGPHGKN_02692 568703.LGG_02345 0.0 889.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F3QA@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepE - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 NAGPHGKN_02693 568703.LGG_02346 9.04e-308 841.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F49B@33958|Lactobacillaceae 91061|Bacilli E Peptidase C1-like family pepC - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 NAGPHGKN_02694 568703.LGG_02347 1.42e-249 686.0 28MJI@1|root,2Z8NZ@2|Bacteria,1TP66@1239|Firmicutes,4IF47@91061|Bacilli,3F9EY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02695 568703.LGG_02348 7.65e-272 745.0 28MM7@1|root,2Z8B9@2|Bacteria,1UJ2G@1239|Firmicutes,4ISZP@91061|Bacilli,3FBU3@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - NAGPHGKN_02696 568703.LGG_02349 2.55e-212 586.0 COG1131@1|root,COG1131@2|Bacteria,1TQA2@1239|Firmicutes,4HEU0@91061|Bacilli,3FC3T@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_02697 568703.LGG_02350 0.0 1327.0 COG3158@1|root,COG3158@2|Bacteria,1TRUQ@1239|Firmicutes,4HA8Z@91061|Bacilli,3F4CU@33958|Lactobacillaceae 91061|Bacilli P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans NAGPHGKN_02698 568703.LGG_02351 0.0 1688.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4HBU2@91061|Bacilli,3FBUR@33958|Lactobacillaceae 91061|Bacilli G Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N NAGPHGKN_02699 568703.LGG_02352 2.36e-119 342.0 COG0517@1|root,COG0517@2|Bacteria,1TRZD@1239|Firmicutes,4HC4C@91061|Bacilli,3F6K8@33958|Lactobacillaceae 91061|Bacilli K Domain in cystathionine beta-synthase and other proteins. ccpN GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - CBS,HTH_11 NAGPHGKN_02700 568703.LGG_02353 9.8e-158 442.0 COG0588@1|root,COG0588@2|Bacteria,1V2UT@1239|Firmicutes,4HGRK@91061|Bacilli,3F443@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA1 - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 NAGPHGKN_02701 568703.LGG_02354 1.1e-256 705.0 COG4292@1|root,COG4292@2|Bacteria,1VD7Y@1239|Firmicutes,4HMTW@91061|Bacilli,3F4QG@33958|Lactobacillaceae 91061|Bacilli S Bacterial low temperature requirement A protein (LtrA) ltrA - - - - - - - - - - - LtrA NAGPHGKN_02702 568703.LGG_02355 5.45e-61 187.0 294CX@1|root,2ZRSX@2|Bacteria,1W32Y@1239|Firmicutes,4I1C7@91061|Bacilli,3F85H@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02703 568703.LGG_02356 6.93e-228 630.0 COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,4HAU5@91061|Bacilli,3F3N3@33958|Lactobacillaceae 91061|Bacilli C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases lctO - 1.13.12.4 ko:K00467,ko:K10530 ko00620,map00620 - R00319 RC01312 ko00000,ko00001,ko01000 - - - FMN_dh NAGPHGKN_02704 568703.LGG_02357 9.49e-26 96.7 COG3237@1|root,COG3237@2|Bacteria,1VZVB@1239|Firmicutes,4HYP0@91061|Bacilli,3F8QH@33958|Lactobacillaceae 91061|Bacilli S CsbD-like - - - - - - - - - - - - CsbD NAGPHGKN_02705 543734.LCABL_25260 9.56e-189 535.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,3F3Y4@33958|Lactobacillaceae 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose - - 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme NAGPHGKN_02706 543734.LCABL_25270 3.49e-242 671.0 COG0477@1|root,COG2814@2|Bacteria,1TQM0@1239|Firmicutes,4HATA@91061|Bacilli,3F3SE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - ko:K08196 - - - - ko00000,ko02000 2.A.1.15 - - MFS_1,Sugar_tr NAGPHGKN_02707 543734.LCABL_25280 4.06e-146 415.0 COG2820@1|root,COG2820@2|Bacteria,1TSEU@1239|Firmicutes,4HFDH@91061|Bacilli,3F5N6@33958|Lactobacillaceae 91061|Bacilli F Phosphorylase superfamily udp - 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 - - - PNP_UDP_1 NAGPHGKN_02708 543734.LCABL_25290 3.92e-218 610.0 COG0477@1|root,COG2814@2|Bacteria,1TQM0@1239|Firmicutes,4HATA@91061|Bacilli,3F3SE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - ko:K08196 - - - - ko00000,ko02000 2.A.1.15 - - MFS_1,Sugar_tr NAGPHGKN_02709 543734.LCABL_25300 9.32e-118 353.0 COG3835@1|root,COG3835@2|Bacteria,1UKTM@1239|Firmicutes,4HY2V@91061|Bacilli,3F4E9@33958|Lactobacillaceae 91061|Bacilli KT Purine catabolism regulatory protein-like family - - - ko:K02647 - - - - ko00000,ko03000 - - - HTH_30,PucR NAGPHGKN_02711 568703.LGG_02361 2.13e-44 143.0 29PRZ@1|root,30AQ7@2|Bacteria,1U6Z6@1239|Firmicutes,4IGTF@91061|Bacilli,3F8RC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02712 568703.LGG_02362 4.69e-46 148.0 2DKSV@1|root,30APG@2|Bacteria,1U6Y5@1239|Firmicutes,4IGSB@91061|Bacilli,3F8PU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02713 568703.LGG_02364 4.93e-286 782.0 COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,4HFIF@91061|Bacilli,3F5PJ@33958|Lactobacillaceae 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 NAGPHGKN_02714 568703.LGG_02365 5.56e-287 785.0 COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli,3F3W7@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13130 Aldedh NAGPHGKN_02715 568703.LGG_02366 1.38e-189 527.0 COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli,3F4E1@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase NAGPHGKN_02717 568703.LGG_02368 3.96e-120 343.0 29Q5T@1|root,30B4Q@2|Bacteria,1U7IZ@1239|Firmicutes,4IHFS@91061|Bacilli,3F9SF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02718 1215915.BN193_05860 3.66e-36 143.0 COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HBVW@91061|Bacilli,1YC4W@1357|Lactococcus 91061|Bacilli V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD NAGPHGKN_02719 889201.HMPREF9422_0823 6.62e-69 218.0 COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli 91061|Bacilli V ABC transporter, ATP-binding protein salX - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_02721 568703.LGG_02369 1.16e-179 502.0 COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,4HG4C@91061|Bacilli,3FCAD@33958|Lactobacillaceae 91061|Bacilli M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase NAGPHGKN_02722 568703.LGG_02370 0.0 998.0 COG4932@1|root,COG4932@2|Bacteria,1UY9B@1239|Firmicutes,4HW31@91061|Bacilli,3F6KV@33958|Lactobacillaceae 91061|Bacilli M Cna protein B-type domain - - - - - - - - - - - - GramPos_pilinD1 NAGPHGKN_02723 568703.LGG_02371 0.0 893.0 COG4932@1|root,COG4932@2|Bacteria,1VSXA@1239|Firmicutes,4HTS0@91061|Bacilli,3F4SG@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - GramPos_pilinD1,Gram_pos_anchor NAGPHGKN_02724 568703.LGG_02372 0.0 1877.0 COG4932@1|root,COG4932@2|Bacteria,1VRZM@1239|Firmicutes,4HTFC@91061|Bacilli,3F8GT@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - - NAGPHGKN_02725 568703.LGG_02373 4.45e-133 377.0 2AYWY@1|root,31R2N@2|Bacteria,1UPXG@1239|Firmicutes,4IVCM@91061|Bacilli,3F66A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02726 568703.LGG_02374 4.38e-285 779.0 COG3410@1|root,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,4HBI0@91061|Bacilli,3F47M@33958|Lactobacillaceae 91061|Bacilli N Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075,GIY-YIG NAGPHGKN_02727 568703.LGG_02375 4.88e-263 719.0 COG1073@1|root,COG1073@2|Bacteria,1UF81@1239|Firmicutes,4HI1Q@91061|Bacilli,3FBVJ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 NAGPHGKN_02728 568703.LGG_02376 2.1e-75 230.0 COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,4HH0D@91061|Bacilli,3F84P@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 NAGPHGKN_02729 568703.LGG_02377 5.62e-75 224.0 COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,4HKBS@91061|Bacilli,3F7N2@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family padR - - ko:K10947 - - - - ko00000,ko03000 - - - PadR NAGPHGKN_02730 568703.LGG_02378 5.59e-176 491.0 2AG9B@1|root,30AYZ@2|Bacteria,1U7AB@1239|Firmicutes,4IH59@91061|Bacilli,3F976@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02731 568703.LGG_02379 1.93e-170 477.0 2AG9B@1|root,316EU@2|Bacteria,1U76R@1239|Firmicutes,4IH1J@91061|Bacilli,3F91S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02732 568703.LGG_02380 1.23e-58 181.0 2DEZ9@1|root,2ZPV3@2|Bacteria,1W247@1239|Firmicutes,4I0IP@91061|Bacilli,3F8UH@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun NAGPHGKN_02733 568703.LGG_02381 1.07e-237 654.0 COG0667@1|root,COG0667@2|Bacteria,1UKPC@1239|Firmicutes,4HCF8@91061|Bacilli,3F5X5@33958|Lactobacillaceae 91061|Bacilli C Aldo/keto reductase family tas - - - - - - - - - - - Aldo_ket_red NAGPHGKN_02734 568703.LGG_02383 0.0 881.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,4HU4D@91061|Bacilli,3F4FR@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE,ThrE_2 NAGPHGKN_02735 568703.LGG_02384 5.9e-78 232.0 2BTF9@1|root,32NMI@2|Bacteria,1U8E8@1239|Firmicutes,4IIC5@91061|Bacilli,3FAW0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02736 568703.LGG_02385 9.56e-195 549.0 COG0845@1|root,COG0845@2|Bacteria,1V5C8@1239|Firmicutes,4HHKB@91061|Bacilli,3F5W4@33958|Lactobacillaceae 91061|Bacilli M Transport protein ComB mesE - - ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko02000 3.A.1.112,8.A.1,8.A.1.4.2 - - HlyD_3 NAGPHGKN_02737 568703.LGG_02385 8.2e-77 242.0 COG0845@1|root,COG0845@2|Bacteria,1V5C8@1239|Firmicutes,4HHKB@91061|Bacilli,3F5W4@33958|Lactobacillaceae 91061|Bacilli M Transport protein ComB mesE - - ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko02000 3.A.1.112,8.A.1,8.A.1.4.2 - - HlyD_3 NAGPHGKN_02738 568703.LGG_02386 1.04e-198 568.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli,3F3QF@33958|Lactobacillaceae 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 NAGPHGKN_02739 568703.LGG_02386 1e-283 790.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli,3F3QF@33958|Lactobacillaceae 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 NAGPHGKN_02741 568703.LGG_02387 5.99e-287 787.0 COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,4HH4V@91061|Bacilli 91061|Bacilli T ATPase histidine kinase DNA gyrase B HSP90 domain protein comD - 2.7.13.3 ko:K07706,ko:K12294 ko02020,ko02024,map02020,map02024 M00495,M00496 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 NAGPHGKN_02742 568703.LGG_02388 1.58e-170 478.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,3F3VI@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain plnD - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg NAGPHGKN_02743 568703.LGG_02390 1.3e-59 184.0 2EQ91@1|root,33HV8@2|Bacteria,1W5QW@1239|Firmicutes,4I1R5@91061|Bacilli,3FBUP@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun NAGPHGKN_02744 568703.LGG_02391 1.59e-30 107.0 2AIQB@1|root,31972@2|Bacteria,1U866@1239|Firmicutes,4II3R@91061|Bacilli,3FAKI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02748 568703.LGG_02395 8.4e-170 476.0 COG1266@1|root,COG1266@2|Bacteria,1W74D@1239|Firmicutes,4HXYG@91061|Bacilli,3F80E@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi NAGPHGKN_02749 568703.LGG_02397 2.35e-91 268.0 COG1959@1|root,COG1959@2|Bacteria,1VG8M@1239|Firmicutes,4HYHM@91061|Bacilli,3F6QY@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - Rrf2 NAGPHGKN_02750 568703.LGG_02398 0.0 873.0 COG0477@1|root,COG0477@2|Bacteria,1UHNW@1239|Firmicutes,4IS4S@91061|Bacilli,3FCCP@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily norB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K08170 - M00702 - - ko00000,ko00002,ko01504,ko02000 2.A.1.3.23,2.A.1.3.59 - - MFS_1,Sugar_tr NAGPHGKN_02751 568703.LGG_02399 1.05e-70 213.0 29PYM@1|root,30AX3@2|Bacteria,1U77W@1239|Firmicutes,4IH2P@91061|Bacilli,3F935@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02752 568703.LGG_02400 1.59e-71 215.0 2CCCW@1|root,2ZFAQ@2|Bacteria,1W39Y@1239|Firmicutes,4I054@91061|Bacilli,3F8D6@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun NAGPHGKN_02753 568703.LGG_02401 3.98e-229 630.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,3F4U1@33958|Lactobacillaceae 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red NAGPHGKN_02754 568703.LGG_02403 1.49e-167 469.0 COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,3F468@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short NAGPHGKN_02755 568703.LGG_02404 1.61e-274 751.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,3F3UQ@33958|Lactobacillaceae 91061|Bacilli C Oxidoreductase yqiG - - - - - - - - - - - Oxidored_FMN NAGPHGKN_02756 568703.LGG_02405 5.39e-32 115.0 29PFU@1|root,30ADZ@2|Bacteria,1U6IN@1239|Firmicutes,4IGB1@91061|Bacilli,3F7ZS@33958|Lactobacillaceae 91061|Bacilli S Short C-terminal domain - - - - - - - - - - - - SHOCT NAGPHGKN_02757 568703.LGG_02406 0.0 872.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,3F3K0@33958|Lactobacillaceae 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 NAGPHGKN_02758 568703.LGG_02407 2.58e-171 480.0 29Q1N@1|root,30B08@2|Bacteria,1U7C1@1239|Firmicutes,4IH7B@91061|Bacilli,3F9BP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02767 568703.LGG_02500 7.17e-104 300.0 COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli,3F53E@33958|Lactobacillaceae 91061|Bacilli K Belongs to the CtsR family ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03708 - - - - ko00000,ko03000 - - - CtsR NAGPHGKN_02768 568703.LGG_02499 0.0 1593.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3F3RV@33958|Lactobacillaceae 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR NAGPHGKN_02769 568703.LGG_02498 0.0 2358.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,3F4ET@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 NAGPHGKN_02770 568703.LGG_02497 0.0 2407.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,3F3KF@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 NAGPHGKN_02771 568703.LGG_02496 2.84e-109 315.0 29Q94@1|root,30B88@2|Bacteria,1U7QC@1239|Firmicutes,4IHMP@91061|Bacilli,3FA0H@33958|Lactobacillaceae 91061|Bacilli - - - - 3.4.23.43 ko:K02236 - M00429 - - ko00000,ko00002,ko01000,ko02044 - - - - NAGPHGKN_02772 543734.LCABL_26780 3.06e-44 164.0 COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,3F7WQ@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - Cna_B,Collagen_bind,FctA,Gram_pos_anchor NAGPHGKN_02773 543734.LCABL_26780 0.0 3774.0 COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,3F7WQ@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - Cna_B,Collagen_bind,FctA,Gram_pos_anchor NAGPHGKN_02774 568703.LGG_02495 3.18e-92 270.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli,3F64B@33958|Lactobacillaceae 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 NAGPHGKN_02775 1423732.BALS01000083_gene2031 2.06e-108 312.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,3F3RX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 NAGPHGKN_02776 568703.LGG_02493 0.0 1378.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,3F3JR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 NAGPHGKN_02777 568703.LGG_02491 1.67e-250 687.0 COG2378@1|root,COG2378@2|Bacteria,1VVQ0@1239|Firmicutes,4HW20@91061|Bacilli,3FB7T@33958|Lactobacillaceae 91061|Bacilli K WYL domain - - - - - - - - - - - - WYL NAGPHGKN_02778 568703.LGG_02490 5.85e-139 392.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HVUV@91061|Bacilli,3FCCT@33958|Lactobacillaceae 91061|Bacilli O C-terminal domain of 1-Cys peroxiredoxin ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA NAGPHGKN_02779 568703.LGG_02489 1.26e-90 266.0 COG3223@1|root,COG3223@2|Bacteria,1V9CG@1239|Firmicutes,4HIMW@91061|Bacilli 91061|Bacilli S Phosphate-starvation-inducible E psiE - - ko:K13256 - - - - ko00000 - - - PsiE NAGPHGKN_02780 1423732.BALS01000005_gene1068 1.09e-66 202.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,3F6KC@33958|Lactobacillaceae 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 NAGPHGKN_02781 568703.LGG_02487 1.4e-146 413.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli,3F45I@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 NAGPHGKN_02782 568703.LGG_02486 3.43e-141 399.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,3F3QD@33958|Lactobacillaceae 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 NAGPHGKN_02783 568703.LGG_02485 5.07e-62 190.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli,3F6Z2@33958|Lactobacillaceae 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 NAGPHGKN_02784 568703.LGG_02484 2.07e-200 555.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,3F3XI@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C NAGPHGKN_02785 1423732.BALS01000005_gene1073 5.26e-63 192.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,3F6XP@33958|Lactobacillaceae 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 NAGPHGKN_02786 1423732.BALS01000005_gene1074 4.5e-73 219.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,3F6K6@33958|Lactobacillaceae 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 NAGPHGKN_02787 568703.LGG_02481 2.92e-153 431.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,3F3Q8@33958|Lactobacillaceae 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C NAGPHGKN_02788 1423732.BALS01000005_gene1076 1.96e-98 286.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,3F653@33958|Lactobacillaceae 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 NAGPHGKN_02789 1423732.BALS01000005_gene1077 4.53e-33 114.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,3F82Z@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 NAGPHGKN_02790 1423732.BALS01000005_gene1078 9.86e-54 168.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,3F7FX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 NAGPHGKN_02791 543734.LCABL_26600 1.73e-77 231.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli,3F6GT@33958|Lactobacillaceae 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 NAGPHGKN_02792 568703.LGG_02476 1.67e-66 202.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,3F6X5@33958|Lactobacillaceae 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 NAGPHGKN_02793 568703.LGG_02475 1.23e-123 352.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,3F3Q7@33958|Lactobacillaceae 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C NAGPHGKN_02794 543734.LCABL_26570 1.32e-88 260.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,3F64E@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 NAGPHGKN_02795 568703.LGG_02472 3.7e-123 351.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,3F4G5@33958|Lactobacillaceae 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 NAGPHGKN_02796 568703.LGG_02471 5.63e-77 229.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,3F6KN@33958|Lactobacillaceae 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p NAGPHGKN_02797 568703.LGG_02470 8.15e-109 314.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,3F3VY@33958|Lactobacillaceae 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C NAGPHGKN_02798 1423732.BALS01000005_gene1086 1.83e-33 115.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli,3F7ZU@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 NAGPHGKN_02799 1423732.BALS01000005_gene1087 1.42e-92 271.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,3F675@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A NAGPHGKN_02800 568703.LGG_02467 1.63e-297 814.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,3F4FV@33958|Lactobacillaceae 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY NAGPHGKN_02801 568703.LGG_02466 3.86e-157 440.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,3F3KB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid NAGPHGKN_02802 543734.LCABL_26490 4.15e-46 148.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,3F7CW@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a NAGPHGKN_02803 543734.LCABL_26480 6.38e-20 79.7 COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4HR2X@91061|Bacilli,3F8TC@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 NAGPHGKN_02804 568703.LGG_02463 2.66e-76 228.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,3F6GN@33958|Lactobacillaceae 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 NAGPHGKN_02805 543734.LCABL_26460 3.82e-82 243.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,3F67D@33958|Lactobacillaceae 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 NAGPHGKN_02806 568703.LGG_02461 1.8e-218 603.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,3F3W6@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L NAGPHGKN_02807 568703.LGG_02460 2.94e-80 238.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli,3F6GJ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 NAGPHGKN_02808 568703.LGG_02459 3.39e-148 418.0 2BKGG@1|root,32EXB@2|Bacteria,1U7Q7@1239|Firmicutes,4IHMI@91061|Bacilli,3FA0B@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02809 568703.LGG_02458 2.32e-197 547.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,3F3VD@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran NAGPHGKN_02810 568703.LGG_02457 4.3e-203 562.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,3F48E@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran NAGPHGKN_02811 568703.LGG_02456 5.43e-185 514.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,3F3UW@33958|Lactobacillaceae 91061|Bacilli U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ NAGPHGKN_02812 568703.LGG_02455 1.44e-30 113.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,3F4KC@33958|Lactobacillaceae 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 NAGPHGKN_02813 568703.LGG_02455 9.7e-135 384.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,3F4KC@33958|Lactobacillaceae 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 NAGPHGKN_02814 568703.LGG_02454 3.52e-175 489.0 COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,4HUDT@91061|Bacilli,3FC68@33958|Lactobacillaceae 91061|Bacilli K TipAS antibiotic-recognition domain tipA - - - - - - - - - - - MerR_1,TipAS NAGPHGKN_02815 568703.LGG_02452 1.28e-45 147.0 29PH8@1|root,30AFD@2|Bacteria,1U6KC@1239|Firmicutes,4IGD6@91061|Bacilli,3F83D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02816 568703.LGG_02451 3.01e-163 457.0 COG1136@1|root,COG1136@2|Bacteria,1UYJ6@1239|Firmicutes,4HF89@91061|Bacilli,3F5SR@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NAGPHGKN_02817 568703.LGG_02450 7.16e-236 650.0 COG0577@1|root,COG0577@2|Bacteria,1TVQ4@1239|Firmicutes,4IRU4@91061|Bacilli,3FBQ0@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX NAGPHGKN_02818 568703.LGG_02449 2.05e-134 381.0 COG1309@1|root,COG1309@2|Bacteria,1VD4H@1239|Firmicutes,4HNBF@91061|Bacilli,3F5VC@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N NAGPHGKN_02819 568703.LGG_02448 4.23e-104 300.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,3F696@33958|Lactobacillaceae 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 NAGPHGKN_02820 543734.LCABL_26320 8.98e-86 253.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,3F656@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 NAGPHGKN_02821 568703.LGG_02444 7.22e-264 725.0 COG0477@1|root,COG0477@2|Bacteria,1UHQE@1239|Firmicutes,4IS66@91061|Bacilli,3FBVQ@33958|Lactobacillaceae 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 NAGPHGKN_02822 568703.LGG_02443 0.0 1107.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli,3F5Y6@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran NAGPHGKN_02823 568703.LGG_02442 1.16e-66 218.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli,3F5RW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_tran NAGPHGKN_02824 568703.LGG_02442 0.0 905.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli,3F5RW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_tran NAGPHGKN_02826 1449337.JQLL01000001_gene1688 3.92e-28 106.0 COG2337@1|root,COG2337@2|Bacteria,1VXWG@1239|Firmicutes,4HXKD@91061|Bacilli 91061|Bacilli T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin NAGPHGKN_02828 568703.LGG_02440 1.06e-156 439.0 COG3382@1|root,COG3382@2|Bacteria,1V50R@1239|Firmicutes,4IR12@91061|Bacilli,3FC8T@33958|Lactobacillaceae 91061|Bacilli S B3/4 domain - - - - - - - - - - - - B3_4 NAGPHGKN_02829 568703.LGG_02439 6.12e-190 528.0 COG0600@1|root,COG0600@2|Bacteria,1TQ26@1239|Firmicutes,4HCJ7@91061|Bacilli,3F4W8@33958|Lactobacillaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component ssuC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0042908,GO:0042910,GO:0042918,GO:0042959,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K15554 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.2 - - BPD_transp_1 NAGPHGKN_02830 568703.LGG_02438 5.81e-155 436.0 COG1116@1|root,COG1116@2|Bacteria,1TRE2@1239|Firmicutes,4HAHM@91061|Bacilli,3F5YE@33958|Lactobacillaceae 91061|Bacilli P ATPases associated with a variety of cellular activities ssuB - - ko:K15555 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.17.2 - - ABC_tran NAGPHGKN_02831 568703.LGG_02437 5.68e-298 813.0 COG1835@1|root,COG1835@2|Bacteria,1V8A9@1239|Firmicutes,4HJ67@91061|Bacilli,3F5JA@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 NAGPHGKN_02832 568703.LGG_02436 0.0 1007.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,3FC48@33958|Lactobacillaceae 91061|Bacilli IQ AMP-binding enzyme C-terminal domain - - 6.2.1.48 ko:K02182 - - - - ko00000,ko01000 - - - AMP-binding,AMP-binding_C NAGPHGKN_02833 568703.LGG_02435 2.26e-218 604.0 COG0715@1|root,COG0715@2|Bacteria,1TPI2@1239|Firmicutes,4HDP6@91061|Bacilli,3F4DK@33958|Lactobacillaceae 91061|Bacilli P NMT1-like family ssuA - - ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - NMT1,NMT1_2 NAGPHGKN_02834 568703.LGG_02433 0.0 1832.0 COG3408@1|root,COG3408@2|Bacteria,1TSVY@1239|Firmicutes,4HWSX@91061|Bacilli,3F4M6@33958|Lactobacillaceae 91061|Bacilli G Bacterial alpha-L-rhamnosidase concanavalin-like domain - - 3.2.1.40 ko:K05989 - - - - ko00000,ko01000 - - - Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N NAGPHGKN_02835 568703.LGG_02432 0.0 987.0 COG2211@1|root,COG2211@2|Bacteria,1U037@1239|Firmicutes,4HBZK@91061|Bacilli,3F4MV@33958|Lactobacillaceae 91061|Bacilli G MFS/sugar transport protein - - - ko:K03292,ko:K16210 - - - - ko00000,ko02000 2.A.2,2.A.2.5 - - MFS_2 NAGPHGKN_02836 568703.LGG_02431 5.96e-87 256.0 COG0239@1|root,COG0239@2|Bacteria,1U4G6@1239|Firmicutes,4IE88@91061|Bacilli,3F6R4@33958|Lactobacillaceae 91061|Bacilli U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB1 - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB NAGPHGKN_02837 568703.LGG_02430 3.3e-70 212.0 COG0239@1|root,COG0239@2|Bacteria,1VM30@1239|Firmicutes,4HRC4@91061|Bacilli,3F8A8@33958|Lactobacillaceae 91061|Bacilli U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB NAGPHGKN_02839 568703.LGG_02427 2.99e-27 99.0 29QM9@1|root,30BKW@2|Bacteria,1U8AT@1239|Firmicutes,4II8S@91061|Bacilli,3FAS5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02840 568703.LGG_02426 5.73e-209 578.0 COG0803@1|root,COG0803@2|Bacteria,1V110@1239|Firmicutes,4HZ7G@91061|Bacilli,3FBJR@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family psaA - - ko:K02077,ko:K11707 ko02010,map02010 M00244,M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA NAGPHGKN_02841 568703.LGG_02425 7.54e-113 324.0 29Q79@1|root,30B6A@2|Bacteria,1U7MC@1239|Firmicutes,4IHIH@91061|Bacilli,3F9WH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02842 568703.LGG_02424 1.4e-152 428.0 COG0702@1|root,COG0702@2|Bacteria,1UJSC@1239|Firmicutes,4HCVT@91061|Bacilli,3F4ZZ@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 NAGPHGKN_02843 568703.LGG_02423 2.35e-215 595.0 COG0803@1|root,COG0803@2|Bacteria,1V110@1239|Firmicutes,4HZ7G@91061|Bacilli,3FBJR@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family psaA - - ko:K02077,ko:K11707 ko02010,map02010 M00244,M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA NAGPHGKN_02844 568703.LGG_02422 8.32e-56 174.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HKK1@91061|Bacilli,3F7KX@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 NAGPHGKN_02845 568703.LGG_02421 1.61e-168 471.0 COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,4HA2W@91061|Bacilli,3F4VW@33958|Lactobacillaceae 91061|Bacilli P ABC transporter mntB - 3.6.3.35 ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 M00243,M00244,M00792 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.15 - - ABC_tran NAGPHGKN_02846 568703.LGG_02420 9.44e-186 519.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli,3F4JM@33958|Lactobacillaceae 91061|Bacilli U ABC 3 transport family mtsB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K19972,ko:K19976 ko02010,map02010 M00791,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.14,3.A.1.15.15,3.A.1.15.2 - - ABC-3 NAGPHGKN_02847 568703.LGG_02419 1.55e-224 619.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli,3F4B9@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family mntA - - ko:K19975,ko:K19976 ko02010,map02010 M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.15 - - ZnuA NAGPHGKN_02848 568703.LGG_02418 1.68e-67 205.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,3F7DH@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, ArsR family czrA - - ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 NAGPHGKN_02849 568703.LGG_02417 2.4e-144 407.0 COG0053@1|root,COG0053@2|Bacteria,1V9B6@1239|Firmicutes,4HJTJ@91061|Bacilli,3F4M1@33958|Lactobacillaceae 91061|Bacilli P Cation efflux family - - - - - - - - - - - - Cation_efflux NAGPHGKN_02850 568703.LGG_02416 2.5e-34 117.0 2FB4N@1|root,343B1@2|Bacteria,1VZEN@1239|Firmicutes,4HYPA@91061|Bacilli,3F944@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02851 568703.LGG_02415 0.0 1063.0 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli,3F3XB@33958|Lactobacillaceae 91061|Bacilli Q Multicopper oxidase sufI - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 NAGPHGKN_02852 568703.LGG_02414 6.76e-305 834.0 COG0477@1|root,COG0477@2|Bacteria,1UJ8F@1239|Firmicutes,4IT4C@91061|Bacilli,3FBUG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_5 NAGPHGKN_02853 568703.LGG_02413 4.42e-84 248.0 29PE3@1|root,32D7A@2|Bacteria,1U7IM@1239|Firmicutes,4IHFA@91061|Bacilli,3F9RV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - NAGPHGKN_02854 568703.LGG_02412 0.0 1701.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase atp2C1 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 NAGPHGKN_02855 568703.LGG_02411 0.0 998.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp NAGPHGKN_02856 568703.LGG_02410 7.48e-25 92.8 2BSE3@1|root,32MG2@2|Bacteria,1U8AV@1239|Firmicutes,4II8V@91061|Bacilli,3FASA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - ## 2641 queries scanned ## Total time (seconds): 1.9286932945251465 ## Rate: 1369.32 q/s