LOCUS       gnlProkkaHNCLKEEJ_43    2295 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HNCLKEEJ_43.
ACCESSION   gnlProkkaHNCLKEEJ_43
VERSION     gnlProkkaHNCLKEEJ_43
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 00:50:50
            Original ID  :: gnl|Prokka|HNCLKEEJ_43
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2295
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2295
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1:1652]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..1652
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..2295
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2295
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(2..934)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 112.8;
                     E-value: 2.6e-34)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_1"
                     /sec_met_domain="CTP_transf_like (E-value: 3.6e-14,
                     bitscore: 40.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.2e-71, bitscore:
                     228.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 7.5e-36, bitscore:
                     111.5, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVCEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLI"
     CDS             complement(954..1652)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.4e-15, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKDALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             complement(1666..2295)
                     /locus_tag="ctg43_3"
                     /transl_table=11
                     /translation="MLRQFFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIF
                     TQTEVPIAVFVLVLMFLIVFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWW
                     MILSGLGLYMGYIPFTYLIERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSA
                     DISWTVMLMRTALFSGFVSVLSIFAIYCYFKQQLNSLILIPSEIHD"
ORIGIN
        1 caataaggct ttcgatacgc gcaatgatca taaagtcacc ggtgacctgg gcattcttcc
       61 ctgctctgat cttatcgcag aaaccctcga tactatcctg agtctggata gcgtcagtac
      121 caaaaaggga attcttcttc agaccaactt tatcttcaat gattaccgca gaaatgccgt
      181 gacgttccag agtgcgcaca gtaaagacaa agtgttcgat cttgccaccc gtgtctccat
      241 caaaaataat aggcttggtg gtgcattcaa ggatattgtt caggtcctgt aaacgggtgg
      301 taaggtcgac cgcttcaata tccggtttac ccttactcgt agagtcggtc aggctgctgg
      361 accacatgcc gtcaaagacc tcgcgcttat cacccttctg gacttcaaga ttctcaataa
      421 tcagaccgca aagaccgtcg tgagcctcca ggatacggac cacaggcttg gcctggatca
      481 ggcggcggag ggacttaaga cgtacgtcag gggtagtccc gatcgccttg atatccttgt
      541 cgagcgagga ggagttgatg ccccgggtat aagggatctc gattaccttg cccccctggg
      601 cgttcatcac ctcaaaaacc tgttcgcgca cctcgcgcaa cgggcccgtt ttccagtcgt
      661 cgccgtggat gatatagtca ggcttgagtt tttccagatt cggaacatag ctccaatcct
      721 cctggggaac aacttcgcaa acccctttga tattctcaac aacctcctta cgctgatcat
      781 aggtaaggta agggaggcgt ttgtgttcgg cgatggcctt gtccgtcagc agaccgacga
      841 tgacatcacc gtatttagta gcttcatgaa taatatggat caaccccgga tgcatgatat
      901 ccgcggtcat accgacatag attttcttgt tcatatatgg aaaagatttg tttttaacaa
      961 tagcggatga tgtgctcctc agcatacgaa aggtcggctt catcatcgat ttcataccat
     1021 ttaagaccct ccaccctgag cacacggaca ggggaaacgg aacgggacat gcggagcagt
     1081 tcgtactcgt aacccagttt aggctgggac tccaggatgg tcgcataatc ggcgcacatc
     1141 cggcggtaga aagtattgga aagtttatgg ataccgacca gctcgccttt tgcctcaagg
     1201 gcgtccttgt ctaccgaaca ggaagtaagg atgtgattgc ggtcatattc cacataatac
     1261 tgatcctgga acttggtcag agaagagaca agcatcacat ccgggaattc gtcatccagc
     1321 agcgagagga tggccttgcg ttcaaaaaca aggtccgatt caagcagcag gaaactgtca
     1381 tcgcctatca cgtcacgcgt attgtacaga gtgtacatac tgttagtatc ggcataacgg
     1441 ggactgaaac aggtctctat ctgggggaaa tccgcctgaa gggcttcata agcctctttt
     1501 ttataacccg taccgaggat gatacgttcg ataccgcagg aaagaagggt ttcgatagag
     1561 cggataatca taggttttcc accaacctcc acaaaacctt tgggcacaag ctcggtataa
     1621 tgcccgaagc gggtaccaag accggcagcc atgatcattg ctgttttaat catgaatttc
     1681 agagggaatt aatataagtg aattcaattg ttgcttgaaa taacagtaaa tcgcaaaaat
     1741 cgacaggaca gaaacaaatc ctgaaaaaag ggcagtacgc atcagcatga cagtccagga
     1801 aatgtcagca gaaacgaagt tcttgaccat aaacacaccc gtagtgccca gatagccgaa
     1861 agaatcggcc aaataaataa taaaaacagc cgtactaacc accctaaggg aagcaatcag
     1921 acgttctatc aggtaagtga aaggaatata ccccatatac agaccaagac cggaaagaat
     1981 catccaccaa ataggagaaa gaaaaccgta cacataaagc aatgtggaaa aaaccattaa
     2041 ggaaccgcct gtgacggcga tgcaataaat gatattaaga gccaaacggt tattacggac
     2101 aaacacaatc aggaacatca gtacaaggac aaaaacggca atgggaacct ctgtctgagt
     2161 aaagatcatt gcaccctcaa tatggagctc cttccaaata tcggcagcga aagagtcacg
     2221 aagctcacgg aacacggtca gggcaccgta aaaaacaacc agcatgcaga ttccccaaaa
     2281 gaattgcctc aaaaa
//
