LOCUS       gnlProkkaOCLPFKJG_11   11727 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OCLPFKJG_11.
ACCESSION   gnlProkkaOCLPFKJG_11
VERSION     gnlProkkaOCLPFKJG_11
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 06:12:26
            Original ID  :: gnl|Prokka|OCLPFKJG_11
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11727
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11727
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2453:6727]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2454..6727
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11727
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11727
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             147..671
                     /locus_tag="ctg11_1"
                     /transl_table=11
                     /translation="MSEQQKYWFAARTRDKQEFAIRDSLEKLKTELDLNYYLPTQFVIR
                     QLKYRRKRVEVPVIKNLIFIQATKQDACDISNKYNIQLFYMKDLLTRAMLIVPDKQMQD
                     FIFVMDLDPNGVSFDNDHLSVGSRVQVVKGDFCGVEGELASEANKTYVVIRIAGVLSAS
                     VKVPKSYLRVI"
     CDS             675..1160
                     /locus_tag="ctg11_2"
                     /transl_table=11
                     /translation="MNTLTSQIEQLQSLAHELLYLGVDGAPIYTDHFRQLNKEVLEQSD
                     ALYPQRGATPEEEANICLALLMGYNATIYNQGDKEEKKQVVLNRCWDVLDQLPATLLKC
                     QLLTYCYGEVFEEELAKEAHTIIESWSNRELLKAEKEIAESLNNLEANPYPYSELHE"
     CDS             1157..2440
                     /locus_tag="ctg11_3"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAAFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             2454..3152
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_4"
                     /sec_met_domain="NTP_transf_3 (E-value: 4.9e-13, bitscore:
                     44.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDNFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             3172..4473
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.9;
                     E-value: 2.2e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_5"
                     /sec_met_domain="CTP_transf_like (E-value: 1.4e-11,
                     bitscore: 39.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 4.5e-121, bitscore:
                     398.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.6e-63, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVCEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPVTK"
     CDS             4485..5621
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_6"
                     /sec_met_domain="TPP_enzyme_N (E-value: 8.4e-21, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.8e-19, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             5618..6727
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 4.5e-34.
                     Score: 109.8. Matches aSDomain:
                     nrpspksdomains_ctg11_7_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 81.8; E-value:
                     7.7e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_7"
                     /sec_met_domain="Aminotran_5 (E-value: 4e-30, bitscore:
                     100.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKALSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMKSVNTVLVNK"
     aSDomain        5708..6496
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg11_7_Aminotran_5.1"
                     /evalue="4.50E-34"
                     /label="ctg11_7_Aminotran_5.1"
                     /locus_tag="ctg11_7"
                     /protein_end="293"
                     /protein_start="30"
                     /score="109.8"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKALSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
     CDS             6740..7558
                     /locus_tag="ctg11_8"
                     /transl_table=11
                     /translation="MLKKRLDYSQLKVIQLNILKDVDAFCRENNITYYLTYGTLLGAVR
                     HQGYIPWDDDIDIAMPRKDYEKFLSNYNLNGSKKNVYQVVAIELNNAYPYPFGKVQDLS
                     TVLLEYSDINYPLGINIDIFPIDGLPVDLKKSDKHFLKIKWLMMIMNLKKVKITIKRSF
                     LKNLILLIGKILTLLIPYRFIVCKMSYIAQRYDYEKSDYVSNLSCPDGKHERTSKRVFE
                     NSIEILFEGNNFYAPIGYHEWLHNIYGDYMKMPPVPERVSHHKFEIYKIL"
     CDS             7561..8556
                     /locus_tag="ctg11_9"
                     /transl_table=11
                     /translation="MCSKDNFLQEVRALCIFTVILLHVPFQGHDNISFNTWLMSKQLIT
                     FPVAVFFFLSGYFYSFRNYKSRIVKLLCPFLFWNMSVHLIKFIRGESGFNIENFLLGNG
                     LPYYYLAVLLQIVLFHYIIFKYWSEMVYRVLSISISIISLMAYYYFSISYSIHFNCYLY
                     FPFWILFYTLGTFGKKYWRNLISKIPFCVILLFILISVFLMFFEANLMYYILFQEGIAG
                     SQVKFSSWVYSILIVLLLLKIDYSIDENVTRNFGTLIGDYSYGVYLIHIFILSLIYKLC
                     IVVFNDNYNVLLPFIAASITLVISVFMIYILNKCLPPFILKFLGLYVKSN"
     CDS             8540..9712
                     /locus_tag="ctg11_10"
                     /transl_table=11
                     /translation="MLKVTDECTACGACLSICPKNCISFKSNEEGFLYPHIDIEKCVDC
                     DLCSKVCFLNDHITPTFRENDISYYAAKAIERCNLSSSGGIFPLLAESVLKNDGVVIGA
                     AWDDKFNVKHILIKSKSELPLLCGSKYIQSNTEKVFKIVKEHLSIQTVLFSGTPCQVKG
                     LKTFLGKDYDNLITVELVCHGVPSPLVFRRYLNGVLKYNNLDISQCSKINFREVKDDIY
                     RFVIYNKTKIPFYEQYTNLYTKTFLQNLFLRNSCYNCKCKLENSVGDFILGDFWGCRDF
                     YPEFYDPKGVSLVIVCTERAKKIWLNLKLSRIEVKKKIVFRSNRHLLKSASYNRNRDLF
                     FKTFIHEAEISLDDILMGYTNKDIWVKVKGLIISVLRFVGLFQLVQLYRK"
     CDS             9709..10767
                     /locus_tag="ctg11_11"
                     /transl_table=11
                     /translation="MKIALLTLPFVNNYGGILQAYALKHFLELRGHSVCIIDRNSNFKI
                     SFIDILRLAKRKFLGNRIRNFAYFKKQYLLPMTSEIITNKEMLLLDEKYQFDIYIVGSD
                     QVWRAIYYRDIKYNFYLDFVSSKRKISFAASFGISSWEYTNTETDIIAKLLMDFSFVSV
                     REDTAVRLCSDYLNINAVQFLDPTFLLDKNEYCCLADCFYSSKKIDIFAYIMGPDSSKD
                     KLIKIISDYSGLSVQSITQSKFSFKKNESIQEWLQNFYKSKFVVTDSFHGLAFSLIFNK
                     PFIVCGFSNRGMGRYESLLRYFSLENRLLYSLEDLKELNLSTIWDINWKEVNAKIAENK
                     RFVLELMQTVGV"
ORIGIN
        1 acgaacgttt tttgaaacac attcgttcgt tctcaacttc taaaaatgtt tcgtaaaatt
       61 tgacggtttg aaagagaaaa gatgtctcgt tcaaaccgcg aagcgcaccc gaaataaagg
      121 aaaatttccc caagtataaa tcgtaaatgt ctgaacaaca gaagtattgg tttgccgccc
      181 gtacccgaga taaacaagag tttgctattc gtgactctct tgaaaaattg aagactgaac
      241 ttgatctcaa ttactatctt cccactcagt ttgtcatccg gcagttgaaa tatcgtcgaa
      301 aacgggtgga agtccctgtt attaagaatc ttatcttcat ccaagctacc aagcaagatg
      361 cttgtgatat ttctaataaa tacaatatcc agctttttta tatgaaagac ctgcttacca
      421 gggctatgct gatagttcct gataaacaga tgcaggactt catatttgtc atggatttag
      481 atccgaatgg cgtcagtttc gataatgacc atttatctgt cggtagcagg gttcaggtag
      541 ttaaaggtga tttctgtggt gtcgagggcg aacttgccag cgaggccaac aaaacttatg
      601 ttgttattcg tattgccggt gtattgagcg ccagcgtcaa agttcctaaa agttatttac
      661 gtgtcattta agttatgaat acactcactt ctcaaattga acaattacag agtctcgcgc
      721 acgagttact ctatttaggt gtggatggtg ctcctattta taccgatcat ttccgtcagt
      781 tgaacaaaga agttttagaa caatccgatg cgttgtatcc tcagcgtggt gctactcccg
      841 aagaggaagc aaacatctgt ctggcattat tgatgggtta caatgcaacc atctataatc
      901 agggtgacaa ggaggagaaa aagcaagttg ttctcaatcg ttgttgggac gtgcttgacc
      961 aacttcctgc tactttattg aaatgccagt tgttgactta ttgttatggt gaggtgtttg
     1021 aagaggagtt ggcgaaagag gcgcatacta tcatagaaag ttggagcaat cgagaacttt
     1081 taaaagctga aaaagaaata gctgaaagtt tgaataattt ggaagctaat ccatatccgt
     1141 acagcgaact acacgaatga ttcgttcctt tctttcccgt tctccccttt acgttttggc
     1201 tctctatgcc agcgttttga tttttctggt ttatacttgt gcctatgcct accgtaagcc
     1261 atttaccgca gccatttatg aaggtgagat tctttgggga ttcgatgtca aaatcctgta
     1321 tgtcctttct gagattatcg gctacgccct ttccaagttc atcggtgttc gtattctgcc
     1381 ttcgatgaaa gcgggtcacc gcatctatta tataataggg ctgcttactt tttccgaagt
     1441 tgctttgttg ggttttgcac ttcttccggt tcctttgaag gtgtgttcta tttttctgag
     1501 cggtcttccc ctgggtatga tctggggtgt catttttagc tatatcgaag gacgtcgtat
     1561 cagtgaaata ttgaatgtcg ggctgagcgt tgctttgata gtctcttccg gtttggtgaa
     1621 aaccttggga caattcgtga tggataattt gcatgtgtcg gaatattgga tgccttttac
     1681 caccggtttg ttggtatacc ctgttatgtt gctttgcagc tggcttctca atcagattcc
     1741 ggctcccaat gagcaagata tcatacagcg taccaaacgt gctccgatgg atggtaaaga
     1801 caggcgtaaa tttttgaggc aattcttctg gggaatctgc atgctggttg ttttttacgg
     1861 tgccctgacc gtgttccgtg agcttcgtga ctctttcgct gccgatattt ggaaggagct
     1921 ccatattgag ggtgcaatga tctttactca gacagaggtt cccattgccg cttttgtcct
     1981 tgtactgatg ttcctgattg tgtttgtccg taataaccgt ttggctctta atatcattta
     2041 ttgcattgcc gtcacaggcg gttccttaat ggttttttcc acattgcttt atgtgtacgg
     2101 ttttctttct cctatttggt ggatgattct ttccggtctt ggtctgtata tggggtatat
     2161 tcctttcact tacctgatag aacgcctgat tgcttccctt agggtggtta gtacggctgt
     2221 ttttattatt tatttggccg attctttcgg ctatctgggc actacgggtg tgtttatggt
     2281 caagaacttc gtttctgctg acatttcctg gactgtcatg ctaatgcgta ctgccctttt
     2341 ttcaggattt gtttctgtcc tgtcgatttt tgcgatttac tgttatttca agcaacaatt
     2401 gaattcactt atattaattc cctctgaaat tcatgattaa aacagcaatg atcatggctg
     2461 ccggtcttgg tacccgcttc gggcattata ccgagcttgt gcccaaaggt tttgtggagg
     2521 ttggtggaaa acctatgatt atccgctcta tcgaaaccct tctttcctgc ggtatcgaac
     2581 gtatcatcct cggtacgggt tataaaaaag aggcttatga agcccttcag gcggatttcc
     2641 cccagataga gacctgtttc agtccccgtt atgccgatac taacagtatg tacactctgt
     2701 acaatacgcg tgacgtgata ggcgatgaca atttcctgct gcttgaatcg gaccttgttt
     2761 ttgaacgcaa ggccatcctc tcgctactgg atgacgaatt cccggatgtg atgcttgtct
     2821 cttctctgac caagttccag gatcagtatt atgtggaata tgaccgcaat cacatcctta
     2881 cttcctgttc ggtagacaag aacgcccttg aggcaaaagg cgagctggtc ggtatccata
     2941 aactttccaa tactttctac cgccggatgt gcgccgatta tgcgaccatc ctggagtccc
     3001 agcctaaact gggttacgag tacgaactgc tccgcatgtc ccgttccgtt tcccctgtcc
     3061 gtgtgctcag ggtggagggt cttaaatggt atgaaatcga tgatgaagcc gacctttcgt
     3121 atgccgagga gcacatcatc cgctattgtt aaaaacaaat cttttccata tatgaacaag
     3181 aaaatctatg tcggtatgac cgcggatatc atgcatccgg ggctgatcca tattattcat
     3241 gaagctacta aatacggtga tgtcatcgtc ggtctgctga cggacaaggc catcgccgaa
     3301 cacaaacgcc tcccttacct tacctatgat cagcgtaagg aggttgttga gaatatcaag
     3361 ggggtttgcg aggttgttcc ccaggaggat tggagctatg ttccgaatct ggaaaaactc
     3421 aagcctgact atatcatcca cggtgacgac tggaaaacgg gtccgttgcg cgaggtgcgc
     3481 gaacaggttt ttgaggtgat gaacgcccag gggggcaagg taatcgagat cccttatacc
     3541 cggggcatca actcctcctc gctcgacaag gatatcaagg cgatcgggac tacccctgac
     3601 gtacgtctta agtccctccg ccgcctgatc caggccaagc ctgtggtccg tatcctggag
     3661 gctcacgacg gtctttgcgg tctgattatt gagaatcttg aagtccagaa gggtgataag
     3721 cgcgaggtct ttgacggcat gtggtccagc agcctgaccg actccacgag taagggtaaa
     3781 ccggatattg aagcggtcga ccttaccacc cgtttacagg acctgaacaa tatccttgaa
     3841 tgtaccacca agcctattat ttttgatgga gacacgggtg gcaagatcga acactttgtc
     3901 tttactgtgc gcactctgga acgtcacggc atttctgcgg taatcattga agataaagtc
     3961 ggtctgaaga agaattccct ttttggtact gacgctatcc agactcagga tagtatcgag
     4021 ggtttctgcg ataagatcag agcagggaag aatgcccagg tcaccggtga ctttatgatc
     4081 attgcgcgta tcgaaagcct tattgccggc aaacccatga gtgacgccct cgaacgtgct
     4141 tatgcctatg tacaggcggg tgcggacggc atcatgatcc acagcaagga taagtcgggt
     4201 gaggatatcc gtgagttctg ccggactttc cgcaaagaat acgcccatgt tcccattgtc
     4261 gttgttccga cgacttatga ccatgtgcac gaatccgaac ttcacgaatg gggtgccaac
     4321 gtagtcattt acgccaacca ccttctccgt gccgcttatc cggccatgat gaacgtggcc
     4381 aggaccatcc ttgaaaacga gcgcgccgag gaggtccgtc cgctttgtat gcctatcaag
     4441 gaaattctgg aattgattcc ggtcactaaa taaatcagac ggttatggta agtgtagaaa
     4501 agatatacga tacgttcctt catcacggtg ttgacttctt tacgggtgtt cccgattccc
     4561 ttttgaagaa tatttgcgcc tatatcacgg atcatgctcc gcgtggtaag catatcatcg
     4621 ccgctaatga aggttccgcg gtgggcattg cctgcggtta ttatatggct tctggcaacg
     4681 ttcctttggt ttatatgcag aactccggtc tgggaaatac ggtgaatccc ctcttgtccc
     4741 ttgcggacga gaaagtgtac agccttcctc ttcttttgct ggtcggctgg cgcggtgagc
     4801 ccggcacaaa agacgaaccc cagcataaga agcagggcga ggttaccctt gatcttctga
     4861 aagccatgaa aattcctttt ataattctgg atacggatga agacgaggcc ctggcgcaga
     4921 tccatgacgc ggttgtctcg gcgaagagcc ggtcgattcc ccatgcgatt gtcatccgta
     4981 aagatacgtt tggaaaatat aaattgcgtc aggaagcctt gaatgactat cctctgtccc
     5041 gcgaggaggc gctaatgcag gttgtcgacc acctcgggga caatgacatt gtggtttcca
     5101 ccacgggcaa gctctcccgt gagcttttcg agtaccgtga atcgaaaggg caggggcacg
     5161 caagggattt cctaactgtg ggttccatgg gtcacagttc ttccattgcc ctggggattg
     5221 cccttgagaa gcctgaccgc cgtgtctact gtcttgacgg tgacggtgcc tttatcatgc
     5281 acatgggtgc tgtcagcaat atcggcgatc tttctcccaa gaattacagg cacgtccttt
     5341 tcaacaacgg tgcgcatgaa tctgtcggcg gtcaacccac gctcggtttc cgtctggata
     5401 tcgcctcgat agcgaaaggt tgcggttatg cgcatgtact gactgcctcc gacaaggaag
     5461 ggctttcgtg tgcgcttgag aagctgtccg gcctgtccgg cccggttctt cttgaaatta
     5521 aggtccggat cgattcacgt gatgatctgg gtcgccctac gactactccg gtagagaata
     5581 aagagcattt tatggcattt ttaaaagata cgcattcatg aatatcgaaa gaaagatcct
     5641 tttgaatccg ggtcccgcca ccacgacgga tacggtgaag ctggcgcagg ttgttcccga
     5701 tatctgtccg cgtgagaaag agtttgcggg tatgatgaaa cagttacgtg acgacctggt
     5761 ccgcgttgcg catggagacc tttccaaaca tacggccgtc ctgttttgcg gctcgggtac
     5821 gatcaatatc gatatctgcc tgaactctct tcttcctgcg gataagaaag ttctggtggt
     5881 caataacggt gcctacagca cccgtgcggt ggaagtctgc gaatattacg gtcttcccca
     5941 tatcgatttg aagttttccg tttacgaact tcccgacctg tcggtaatcg aaaaggcgct
     6001 ttccgacaat ccggacatcg ctttggtcta taccacgcac catgaaacgg gtacgggtat
     6061 cttgaacccc atccgtgaga tcggaaaaat agcccattcg cacggtgccg tttttgttgt
     6121 cgacaccact tcctccctgg gtatgattcc ttttgatatc ggaaaggata atgttgactt
     6181 ttgtatggct tcggctcaga aaggccttca ggccatgacg ggtctttcct ttatcatagg
     6241 tgatgaatcc ctgatacgtg cttcaaggga ttatccgaaa cgctcctact attgtaacct
     6301 ctatttacaa tacgattact ttgagaagac gggtgagatg cattttactc ctcctgttca
     6361 aaccgtttac gcagcccgtc aggctcttga tgaatatttt gcagtaggtg aagaggctaa
     6421 attcgcccgt cacaagaggg tctttgaagc catccataaa ggtttgcaag agcttggtct
     6481 tcagtatgcg atcaaacgtg aatggcagtc gggtcttgtt gtttctgtat tgtatcctga
     6541 tgatcccctc tgggattttg ataaggttca tgattactgc tatgaacgtg gctttacgat
     6601 ctacccgggt aagatttcca caacgaatac attccggctt tgtgcgttgg gagagattga
     6661 tgtggaggat attgagaggt tctttgaggt gatgaaaagc gtaaatacgg tattagttaa
     6721 taaataattt agctcattca tgttgaaaaa aaggttggac tattcccaat taaaggttat
     6781 acagttgaat atattaaaag atgtagatgc tttttgtcgt gaaaataata taacttatta
     6841 tttaacttat gggactttgt tgggggctgt aagacatcaa ggatatattc cttgggatga
     6901 cgatattgat attgctatgc cgaggaaaga ttatgaaaag tttttatcaa attataatct
     6961 aaatggaagt aaaaaaaatg tgtatcaagt tgttgctata gagttaaata atgcttatcc
     7021 ttatcctttt ggaaaggttc aagatttatc aactgtttta ttagaatatt cagatattaa
     7081 ttatccgttg gggataaata ttgatatttt ccctattgat ggattacctg tagaccttaa
     7141 aaaatcagac aaacattttt tgaagataaa gtggttaatg atgataatga atcttaaaaa
     7201 agtaaaaatc acaataaaac gttctttttt gaagaactta atattattaa tagggaagat
     7261 tttgacactt ttgattccat atcgatttat agtgtgcaaa atgtcttata ttgcacagag
     7321 gtatgattat gagaaatctg attatgtttc taacttgtct tgtccagatg ggaaacatga
     7381 acggacgtct aaaagagttt ttgaaaatag tatagagatt ttatttgaag gtaataattt
     7441 ctatgctcct ataggatatc atgaatggct tcataatatt tatggagatt atatgaaaat
     7501 gcctccagtt ccggaaagag tatctcatca taaatttgaa atttataaga tactgtaatc
     7561 atgtgttcta aggataattt tcttcaagaa gttcgtgcat tatgtatatt tactgtaata
     7621 ttgttacatg taccatttca gggacatgat aatataagtt ttaatacttg gctaatgtca
     7681 aagcagttga ttactttccc tgttgctgtg ttcttctttt tatctggata tttttattct
     7741 tttagaaatt ataagagtag aattgttaaa ttgctttgtc cttttttatt ttggaatatg
     7801 agtgtacatc taattaagtt tattagaggg gaaagcggat ttaatattga aaatttttta
     7861 ttaggtaatg gattacctta ttattattta gcagtacttc ttcagattgt gttatttcat
     7921 tacataatct ttaaatattg gagcgaaatg gtatatagag tattgtccat aagtattagt
     7981 attataagtt tgatggccta ttattatttt tccatttctt attctatcca ttttaattgt
     8041 tatctctatt ttcccttttg gatattattc tatactttag gaacatttgg gaaaaaatat
     8101 tggcgtaatt taatatctaa aatacctttt tgtgtaattc tattgtttat tttaatatct
     8161 gtctttttga tgttttttga agctaattta atgtattata ttttgtttca agagggaatt
     8221 gccggctctc aggttaagtt ctcttcctgg gtgtattcta tactaattgt gttgctttta
     8281 cttaaaatag attattcaat agacgaaaat gttactcgaa attttggtac acttataggt
     8341 gactattcat atggagtcta tttaattcat atatttatat tatctttaat ttataaatta
     8401 tgtattgtcg tttttaatga taattataat gtattattgc cttttatcgc agcttctata
     8461 acattggtta tttcagtttt tatgatttat attttaaata aatgtcttcc tccctttata
     8521 cttaaatttt taggattgta tgttaaaagt aactgatgaa tgtacggctt gtggagcttg
     8581 cttgtctata tgtccaaaga actgtatttc ttttaaaagt aatgaagaag gttttttata
     8641 tccacatatt gatatagaaa aatgtgtaga ttgcgatttg tgttctaaag tttgtttttt
     8701 aaatgatcat attactccga cttttaggga aaatgatatc agttattatg cggctaaggc
     8761 tattgaacga tgtaatttga gctcttctgg aggaatattc ccattgcttg cagaatcagt
     8821 tttgaagaat gacggcgtag taataggagc tgcttgggac gataaattta atgtcaaaca
     8881 tattcttatt aaatcaaaaa gtgaactgcc attattatgt ggttcaaaat acatacagag
     8941 taatacagaa aaggtcttca agatagttaa agaacatctg tctattcaaa ctgttctttt
     9001 ctcaggaaca ccttgtcaag tgaaaggact taaaacattt ttgggaaaag attatgataa
     9061 tttgattacg gtcgaattgg tttgtcatgg agttccttca ccattggttt ttagacggta
     9121 tttgaatggg gttttgaaat ataataattt agatatttca cagtgtagta aaattaattt
     9181 tagggaagta aaagatgata tctatagatt tgtgatatat aataagacca aaataccatt
     9241 ttatgaacaa tatacaaatc tttatactaa aacatttctt caaaatttat tcttacgtaa
     9301 ttcttgttat aactgtaaat gtaaattgga aaattccgta ggagatttta tcttaggaga
     9361 cttttgggga tgtagggatt tctatcctga attttatgat ccaaaaggag ttagcttagt
     9421 tattgtttgt actgaacgtg caaaaaaaat atggttaaat ttaaaattat caagaataga
     9481 agttaagaaa aagattgttt ttagaagtaa taggcattta ttaaaatctg catcttataa
     9541 tagaaataga gacttgttct ttaaaacttt tattcatgag gctgagatat cactagatga
     9601 tattttgatg ggatacacaa ataaggatat ttgggttaag gttaaaggtt tgataattag
     9661 tgttttacgt tttgtggggc ttttccaatt agttcaattg tatagaaaat gaaaatagca
     9721 ttacttactt taccatttgt taataattat ggaggaatat tacaagctta tgctttaaaa
     9781 cattttttag agttaagagg gcatagtgtt tgcattatag atagaaattc aaattttaaa
     9841 ataagtttta ttgatatatt acgtcttgca aaaaggaagt ttctgggaaa tagaattcgt
     9901 aactttgctt attttaagaa gcaatattta ttaccaatga catctgagat tataactaat
     9961 aaagaaatgt tattgcttga tgaaaaatat caatttgata tttatattgt tggtagtgac
    10021 caggtttgga gagcaatata ttatagagat attaaatata atttttattt ggattttgtg
    10081 tcgagtaaga ggaagatatc ctttgccgct tcttttggca tatcttcttg ggaatataca
    10141 aacactgaaa ctgatattat tgcaaaactg ttaatggatt tttcttttgt ttctgttaga
    10201 gaagatacag cagtaaggtt atgttctgat tacttgaata ttaatgctgt gcaattccta
    10261 gatccaactt tcttattgga taaaaacgaa tattgttgtc ttgctgattg tttttatagt
    10321 tctaaaaaga ttgatatttt tgcttatata atggggcctg attcatctaa agataaatta
    10381 attaaaataa taagcgatta ttctggcttg agtgttcaat ctataactca aagtaaattc
    10441 tcttttaaaa agaatgaaag tattcaagaa tggctacaaa atttttataa gtcgaaattt
    10501 gttgtaacag actcttttca tggtttagct ttttctttaa tatttaataa accttttatt
    10561 gtttgtggct ttagtaatag aggaatgggg agatatgaat ctttattgag atatttctct
    10621 ttggaaaata gacttttata ttcattggaa gatttaaaag aactaaattt atctactatt
    10681 tgggatataa attggaagga agttaatgct aaaattgctg agaataaaag gtttgtattg
    10741 gagttaatgc agacggtagg tgtataatgt cacttaaaga aaatacaatt tatggtgtac
    10801 tgtggagttc atttgagaaa tttggaactt tatcgataca atttatttac atgattgtga
    10861 tggcaagatt gctatctcct tctgattttg gtatagttgg catgttgaca atttttattt
    10921 ctgtaggcca agttatactt gatagtggtt ttggacaggc tttaataaga ttacaaaaat
    10981 atgatgattt acatttttct tcaattttta taattaatgt tattatggga gttctactct
    11041 atggaatatt attttatatg gctccatata tttctttatt ctatagagaa cctagcttaa
    11101 cattaatttc aagaatatct tttttgattt ttcccatcaa ttcactaagt atagtccaat
    11161 atactttatt agtgaaaaaa atggatttta aatctatttc taaaatatct ttattctcga
    11221 taattttatc tacaatttca ggtattacat atgggtattt ttaccctaat atatttgcac
    11281 tattaattca aaatgtctca ttttattttt ataggctact tttattatgg tattatggaa
    11341 actggaaatt atcatgtcga atttcatgga gtaaattaca agatttgatg ccattctctt
    11401 ttacgttatt agctacaggc tttatttcta ctgtcgtagg agagttgtat tcattgtcta
    11461 ttggtaagtt cttttcttca tctgttttag gtttatattc tcaagcagaa aggttttcga
    11521 aaattccatc tttttctata acagatgttg ttcaacgtgt gacttatcct gcattatcag
    11581 tgttacaaga cgatgatcaa aaattaaagc attcatatag aatggttatt atgtgcacat
    11641 tctttatagt attgcctgta atgctttttc tttttattag cgctggcgaa atttttgaat
    11701 tattatttac tgaaaaatgg gaacagg
//
