LOCUS       gnlProkkaBFFJEIOL_12   21589 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BFFJEIOL_12.
ACCESSION   gnlProkkaBFFJEIOL_12
VERSION     gnlProkkaBFFJEIOL_12
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:40:00
            Original ID  :: gnl|Prokka|BFFJEIOL_12
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 282
            Orig. end    :: 21871
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21589
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11589]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11589
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21589
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21589
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             511..1461
                     /locus_tag="ctg12_2"
                     /transl_table=11
                     /translation="MQKDYETFVEKLEIGIYEATGIPRENISFEKEGGRFAPVGDRLLV
                     KLAEHDDAWEVCGLYTQELFKSYQNGSPFEKIIKEITDDLNRIKKADIYEKTRVIRDYE
                     KTKPRLFIRLLNADKYSADLQDAVYKTLGDIALVLYMKVTEYEGCVTSTKIRQGMLEQW
                     GKECDEVFKEAILNTYFMSPPRIYRWEQMIFNPEYEGESFMNLGDKCELKKDAMGNCLS
                     TTKKTNGAVAVFLPGVAEQLAYMLDSDFYMVFTSVHEVMIHNDKFVEPEDLQCVLQDTI
                     REATPKEDYLTSRIYQYNRETHKFICVTPLEKDEK"
     CDS             complement(1535..2329)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 168.4; E-value:
                     3.5e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg12_3"
                     /transl_table=11
                     /translation="MLELKNIYKTFNPGTINEKRALNGLNLKLNEGDFVTVIGGNGAGK
                     STMLNAVAGTWPVDEGQILIDNIDVTKLSEHKRATYLGRVFQDPMTGTAATMGIEENLA
                     LAKRRGKSRLLRSGITKAEREEYKELLKILGLGLEDRLTSKVGLLSGGQRQALTLLMAT
                     LQKPKLLLLDEHTAALDPKTAAKVLEITDMIVNRDHLTTLMITHNMKDAIAHGNRLIMM
                     MEGKIILDIQGEEKKKLTVKNLLDQFEKASGEEFSNDSALLG"
     CDS             complement(2332..3249)
                     /gene_functions="transport (smcogs)
                     SMCOG1113:inner-membrane translocator (Score: 68.5;
                     E-value: 8.4e-21)"
                     /gene_kind="transport"
                     /locus_tag="ctg12_4"
                     /transl_table=11
                     /translation="MQIITLITALPGAVAQGLIWGIMAIGVYITFRILDIADLTVDGTM
                     CTGGAVCIMMMLSGHNVWISMLAATLAGMLAGLVTGIFHTFMGIPAILAGILTQLSLYS
                     VNLKIMGKANQAINVDKYNLLVSLRHIKNASLSQNTIFIVAVMCVLLIAILYWFFGTEL
                     GCSLRATGCNPNMSRAQGINTNRNKVLGLMISNGLVGLSSALLAQYQGFADVNMGRGSI
                     VIGLAAVIIGEAIFGRIFRNFALRLLAVIFGSILYYLVLQIVIWMGIDTDLLKMLSAIV
                     VALFLAFPYWKGKYFNKPAKRGGK"
     CDS             complement(3400..4464)
                     /locus_tag="ctg12_5"
                     /transl_table=11
                     /translation="MKRKTLAIALAAAMAMGTCAVTASAADGDKYTIGICQLVQHEALD
                     AATQGFKDEVTKELGKDAVTFDEQNAQGDSNTCSTIINSFVSNNVDLILANATPALQAA
                     AAGTSDIPILGTSVTEYGVALGLDDFDGTVGGNISGTADLAPLDQQAAMLNELFPDAKN
                     VGLLYCSAEANSQYQVDTVKAELEKLGYTCEYYAFSDSNDLSSVVTTAADASDVIYVPT
                     DNTVASNTEIINNICLPAKVPVITGEEGICSGCGVATLSISYYDLGVTTGKMAVKILKD
                     GEDISTMPIEYAPNYTKEYNKDICKELGIEVPDDYVAIGEAAEDTEEASDDAEASDKSS
                     DETSEDNTTEEAAR"
     CDS             4728..5492
                     /locus_tag="ctg12_6"
                     /transl_table=11
                     /translation="MAYSIMLDAGHGGQDPGAVYKGRQEKNDNLKLALAVGEILKNKGI
                     DISYTRTGDVYQTPFEKAQLANQAGVDYFISFHRNSSPKENQYNGAEVLIYDKSGIKYQ
                     MAENILGALGEVGFCEIGVKERPGLVVLRRTRMPALLIETGFINSEEDNKLFDNKFSDI
                     AQGIADAILGSLDEETVQEPLYYRVQTGAFRKKENADHMLYQLLEKGYPSFMLHETGLY
                     KVQTGAYQQIGNAVNMEQRLRDDGYSTVIVTK"
     CDS             5733..6386
                     /locus_tag="ctg12_7"
                     /transl_table=11
                     /translation="MHYLRGAVEKTDNEELVMMNDVYEKFLKSSEEFIFAENKPEKSDI
                     IFVPGNSYPQMAEKAAELFKKGMADWILPSGKYSVVNGKFSGVLEKSNVYDKEYGTEWE
                     FLRDVLTKNGVPDQKILKEDQATFTYENAIYSRQVTDHAGLEIERAILCCKSYHARRCL
                     MYYQLLYPETEFYVVPVNADGITRENWRKNEEGIDAVTGELSRIVKQFSLMLER"
     CDS             complement(6390..7673)
                     /gene_functions="other (smcogs) SMCOG1273:hypothetical
                     protein (Score: 355.5; E-value: 7.2e-108)"
                     /gene_kind="other"
                     /locus_tag="ctg12_8"
                     /transl_table=11
                     /translation="MDSSIAFQAVAILILIALSSFFSSAETAMTTVNKIRIQSLAEQGN
                     KRAVILEKIISDSPKMLSTVLIGNNIVNMSVSSLMTTLTIKILGNAYVGIATGILTLLI
                     LIFGEITPKNLATIHAEKLSLAYSRIIYGLMILLTPVVFIVNKITEGVLVILHVNPDEK
                     ANAMTEHELRTLVNVGEKDGVIENEEKQMIYNVFDFGDSTAKDVMIPRIDMTFIDINFS
                     YDELMAVFNEDMHTRFPVYEDNTDNVIGIINMKDLLVYPKDKPFSIRNILREPYFTYEY
                     KATADLMIEMRKASVNLAIVLDEYGATAGLVTLEDLLEEIVGEIRDEYDEDEVEDIKEI
                     QPEREYVVQGSAKLDDINEALHINLESEDYDSIGGYIIEQLDCLPKEGQSVTLESGIRL
                     VVDRLDKNRIELVHIWLPEKKTETEEQP"
     CDS             8019..9527
                     /locus_tag="ctg12_9"
                     /transl_table=11
                     /translation="MSNNITRIRKNKLKGTGIFAAAALTAALIAGNNVPGVIRQVSAAE
                     SQENTVSSLIPDNITLDKPVELANVELPATEYGTFEWADGSFVPAQRVQSCEVLLIPAE
                     GQDLSHVDGWDPESGAVVGYINVIVNSITDGDNSDKTEGSDKTDPTENADPTETPETSS
                     EKPAADENADTDNKEDKESKSDQDNKTDTDNEENKIEEDKTDNKNNKDNNSNADKTDKD
                     TETTGKLEPADDMTQDKEDTKKDDEDGADDNIFDNPVLPDDKDDRPTDAEESLSDEEKE
                     ERAALNHTCDGITVSGVNLPWYVQFRVSSGDSYQFTNESDAMIFQSYEFELWDLKNNTE
                     YEIPNGDYISVTVPVKSGYQYTIEHLLDNGATETIVPSVENGIMVFSTHSFSPFGIAGS
                     RQLVGPDTGNDTDDTDAVTPAPASSDSQSSDSGKNNTVSMNDSSDSNNGSSSDQNDNST
                     ENKAVKNNNTVNTGDTTSIMPFVILFVAAAVIAGVVVFIKKRKK"
     CDS             9577..9927
                     /locus_tag="ctg12_10"
                     /transl_table=11
                     /translation="MKVRAILKSLLFAYALTGVALLLLALVLFAFDLGETAVDAGIIII
                     YVLACFMGGFMAGRIVRKDKYLWGVITGLTYYVLLLTVSVMAKGGWDMSAAHAVTTFFM
                     CTGGGTLGGMLS"
     CDS             10001..10141
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_11"
                     /sec_met_domain="TIGR03973 (E-value: 9.4e-28, bitscore:
                     87.3, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.2e-27, bitscore: 87.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHIKTLNTKNLQNTVKKGGCGECQTSCQSACKTSCTVGNQSCEQ
                     K"
     CDS             10222..11589
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_12"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.7e-29,
                     bitscore: 93.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.8e-16, bitscore: 51.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.7e-14, bitscore: 45.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.2e-20, bitscore:
                     62.9, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLIHRYKSNGFNIVLDINSGCIHLVDEVTYEVLPYLEKGLDTEA
                     IAEKLENKYNREDIETSVKECNKLKEDGMLFTKDVYENVIEEFSNNRQTVVKALCLHIA
                     HDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGSRKNLEVDFFGGEPLMNW
                     QVVKDLVKYGREQEKLHNKKFRFTLTTNGVLLNDEVMEFCNKEMGNVVLSVDGRKEVHD
                     YMRPFRKGAGSYDLIMPKFQKFAESRNQDKYYVRGTFTHHNLDFSKDVLHLADLGFKQI
                     SVEPVVAADTEEYAIREEDIPQIMEEYDTLAKEMIKREKEGKGFNFFHFMIDLTGGPCV
                     YKRLSGCGSGTEYLAVTPWGDFYPCHQFVGEEQYLMGNVNEGITKPEIQKEFGGCNVYT
                     KKDCKDCFARFYCSGGCAANAFHFQGDIKGNYEIGCELQRKRVECAIMIKAALACD"
     CDS             11701..14109
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     38.5; E-value: 6.5e-12)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_13"
                     /transl_table=11
                     /translation="MKKSKGIVVLLLTLILTVFFCFTAAVGIGPTGTGAAKHINTGLDL
                     AGGVSITYQAKESNPTSEEMSDTIYKLQKRVEQYSTEAQVYQEGSDRITVEIPGVTDAD
                     TILNDLGKPGSLYFITKEDADGNQNFTTGQDGYVLSRTMDEIKESGSVVLEGSDVADAQ
                     GGAIQNQGTSGKEYVVSLTLTSDGENSGKTKFAEATKNNVGKQIAIVYDNNIISAPNVN
                     EEISGGKAQISGMSDLEEAQNLASYIRIGSLGLELEELRSSVVAAQLGEEAISTSVLAG
                     AIGLIIVIIFMIIVYRVPGVVAGIALILYTSLMLITLNAFDITLTLPGIAGIILGIGMA
                     VDANVIIYARIREEIGAGVSVRNSIKSGFSKAFSAIFDGNITTLIAAFVLMWLGSGTVK
                     GFAYTLALGIVISMFTALVVSRLVVNALYAVGVRDPKFYGSAKERKAVDFIGKKKVFFI
                     ISIILILCGPAAMFANSHAGNKALNYSLEFSGGTSTTVTFNEDMDIKTIDSEVTPVVEK
                     VTGDKNVQPTKVVGTNQVVIKTRSLNQSEREALQSALVEKFGVDDSTISTESISSTVSS
                     EMRRDAIVAVIVATICMLLYIWFRFKDIRFASSAVLALLHDVLVVLAFYALARVSVGNT
                     FIACMLTIVGYSINATIVIFDRIRENLHSSSREKLAEVVNTSITQTLTRSIYTSFTTFV
                     MVAVLYIMGVSSIREFAAPLMVGVLIGAYSSVCITGALWYVMKKKFTGKGQPAIAAAST
                     STKSSSKPKKTRDVSQKDPTQPKKKNRKRVAERLAAEESAKKQQNDDAE"
     CDS             14226..15938
                     /locus_tag="ctg12_14"
                     /transl_table=11
                     /translation="MEKWVIAAKRADFNQIGQQFHIDPVIARVIRNRDVIGEDKIREYL
                     SGTVQELPSPWLMKDMEKAVDILERKISQKAKIRIIGDYDIDGVTSTYILMKGLARIGA
                     DVDTYIPDRVSDGYGIHAHLIERAETDRIDTIVTCDNGIAAAAEIQMAKDKKMTVIVTD
                     HHEVPYREEKGERRMVLPPADAILNPKQYDCPYPNKNLCGAVVAFKYIAALYERSGVPA
                     EELEDYYELAAIATVGDVMDLQGENRILVKEGLCRLKNTKNKGLQELIRANSLEDAKIT
                     AYHIGFVLGPCINASGRLDTASRSLALLNAKTKEEAARLAGDLTALNQSRKALTEKGKE
                     EAIRIIETTELKNDRVLVVYLPDCHESLAGIIAGRIREKYHKPAFVLTGGETSAKGSGR
                     SIESYSMYEELIKCADLMIQFGGHPMAAGLSIEEKNIEEFRRCLNVNCTLTDEELRPKV
                     VIDVPMPVSYVTKELVEQISLLEPFGKGNTKPVFAQKNLRVLDHSIIGKNKNAVKLKLL
                     DPQGISVEGIYFGEAEEFVNFIREKDSVSVTYYPEINRFRGRESLQIIIQNYC"
     CDS             16086..16610
                     /locus_tag="ctg12_15"
                     /transl_table=11
                     /translation="MKKIEDYVLSIPDFPEPGIIFRDITSVLQDADGLQLAIDSMQDCL
                     KDVDVDVIAGTESRGFIFGVPIAYNLHKPFVPIRKKGKLPRETVSVSYDLEYGSAEIEM
                     HKDSIKPGQKVVIVDDLIATGGTIEAAIKLVEQLGGEVVKVVFLMELAGLKGRERLNGY
                     DVASVICYDGK"
     CDS             16648..18978
                     /locus_tag="ctg12_16"
                     /transl_table=11
                     /translation="MTEITRSTEAKKDEMQIEKEKLESVKRADAAVKTMHDFTSPEVLY
                     KELINSVLKYHPSTDISMIEKAYKVASEAHEGQKRKSGEPYIIHPLCVAIILADLELDK
                     ETIVAGLLHDAVEDTWMTYEEVEKEFGSEVALLVDGVTKLGQLSYSADKVEVQAENLRK
                     MFLAMAKDIRVILIKLADRLHNMRTLQYMRPEKQQEKARETMDIYAPIAMRLGISKIKV
                     ELDDLSLKYLKPDVYYDLVQKVALRKSEREQFVGAIVKEVKKHMDDANIKAQVDGRVKH
                     FFSIYKKMVNQDKTIDQIYDLFAVRILVDTVKDCYAALGVIHEMYKPIPGRFKDYIAMP
                     KPNMYQSLHTTLIGPNGQPFEIQIRTYEMHRTAEYGIAAHWKYKESSDGKVPVGKSEEE
                     KLNWLRQILEWQRDMSDNKEFMSLLKNDLDLFADSVYCFTPQGDVKTLPSGSTPVDFAY
                     SVHSAVGNKMVGARVNGKLVPIEYEIKNGDRIEIITSQNSQGPSRDWLKLVKSTQAKNK
                     INQWFKKELKEDNILKGKEMLAQYARAKGFKITNYTKTQYLEAVLRKYGFRDWDSVLAA
                     IGHGGLKEGQVFNKLVEAYDKENKKNLTDEQVLEAASETQEKLHIAKSKSGIVVKGIHD
                     VAVRFSKCCNPIPGDEIVGFVTRGRGITIHRTDCVNVLNMSETDRTRLIEAEWQQPDTK
                     EKEKYMAEIQVYANNRTGLLVDLSKIFTERKIDLRSINSRTSKQEKATISMSFEIGSKE
                     ELRSLIEKIRQVESVIDVERTTG"
     CDS             19043..19672
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     159.8; E-value: 9.5e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_17"
                     /transl_table=11
                     /translation="MKNLELQKCILGPVYTNCYLLKNKETGELIIVDPADCPEKIELKI
                     SRMSGKPVAILLTHGHFDHILAAQAVKEKYNIPIYACRQEEEMLREPSINMTVHYGRGC
                     SIVPDVFLEDLDVIRMAGFSVQMIHTPGHTKGSCCYYLKDEGVLFSGDTVFYGSVGRTD
                     FPGGSTAEIVKSLHKLVDSLPEETEVFPGHDASTTIGYEKRYNPFV"
     CDS             19665..21179
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_18"
                     /sec_met_domain="PF04055 (E-value: 4.3e-25, bitscore: 80.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCKIGILFENRDFEHDVYELIKAFYPEAEIHTLYENAEAEYDLRF
                     SVERDNDSYIIKYERAENLSKQETEQKGVISADILSKENAGCGIQDAHALRKENKDTIK
                     YALYQLLVKLTGRTLPWGNLTGIRPAKLAMGMIESGMKNTEAAREMRERYLVSPQKTAL
                     AITIANREREILKDIDYENGYSLYIGIPFCPSICLYCSFSSYPLKVWEKRTDEYVEALC
                     REVRETALMMKGRKLDTIYIGGGTPTTLLPHQIRKLLDTVGEAFGYEGLAEFTVEAGRP
                     DSITREKLMTIREYPVTRISVNPQTMNQETLDIIGRRHTVEQTKEAFRLARELGYDNIN
                     MDLIVGLPGEDIHMVERTLEQIRELAPDSITVHSLAVKRAARLNIFKEKYQEMSFENNQ
                     EIMDLTMKTAYEMGMGPYYLYRQKNMKGNFENVGYAKVDKAGIYNILIMEEKQPIIALG
                     AGGSSKLVFDHGQRIERVENVKDVSNYISRIDEMIERKRTAIATWL"
ORIGIN
        1 aatggaatcg ggaatccggt atatcctccg gcgcgagagg agcttgctaa gcatgggatt
       61 gattgtaagg gtaagcgtgc agttcaactg acgaaggcag attatgataa atatgattat
      121 attctcggta tggatcattg gaatctgaag aatatgttaa gaatattgaa atcggatcca
      181 gaggacaagg ttaagcttct tctggattat agtgatgatc cgagggatat cgcagatcca
      241 tggtatacag gtggatttga tgtcacatat tcggatgtgg tggagggctg tgaggctttt
      301 ctggaatatc tgaaagataa aaagaaactg taataaataa tgtcgatgaa atttacttta
      361 caaatagctg tggctatttt atactatgtc tacagcgact cttaaggggg ctttcgctcc
      421 cttattttct tttttccgaa aacggaaagt caacattcaa atcagggcat cctgcccgta
      481 ttattttcaa agtaagaaag gaaactgaat atgcagaaag actatgaaac attcgtagag
      541 aaactggaga ttggtattta cgaggctaca gggattccga gggaaaatat ttcttttgag
      601 aaagaaggcg ggaggtttgc acctgtagga gacagactgc tggtgaagtt agcagagcat
      661 gatgatgcct gggaggtctg tggactttat acacaggaac tttttaaatc ttatcagaat
      721 ggcagtccgt ttgagaaaat tataaaagaa attacagatg atctgaatcg gataaaaaag
      781 gcggatattt atgagaaaac aagagtgatc agggattatg agaagacaaa accccgcctg
      841 tttataagat tgctgaatgc agataaatat tccgcggatc ttcaggatgc ggtgtataaa
      901 actcttggtg atattgcact tgtgctttat atgaaagtta cggaatatga aggatgtgtg
      961 acaagtacaa aaatccggca gggaatgctg gagcagtggg gaaaagaatg tgatgaggtg
     1021 tttaaggagg cgattctcaa tacgtatttc atgagtccgc ccagaattta cagatgggaa
     1081 cagatgattt ttaatccgga atatgaaggt gaaagtttta tgaatctggg ggataagtgt
     1141 gaattgaaga aagatgcaat gggaaattgt ctcagtacaa cgaagaagac aaatggtgca
     1201 gttgcagtgt tcctgccggg agtggcagaa caactggcat atatgctgga ttccgatttc
     1261 tatatggtct ttaccagtgt acatgaggta atgattcata atgataaatt tgtagaacct
     1321 gaagatttgc agtgtgtttt gcaggatacg atcagggagg ccacaccgaa agaggactat
     1381 ctgacatcga gaatctacca gtacaatagg gaaacacata aatttatctg tgtaactccg
     1441 ctggaaaaag atgagaaata aaaatatgag agtactccat aaaaagtact ctcatataaa
     1501 ggatatttag aaacgttatg agtgatttat acggttatcc gagcagtgca gagtcattgc
     1561 tgaactcttc tccgcttgct ttttcaaact gatccagaag atttttaact gtcagttttt
     1621 tcttttcttc tccctgaatg tccagaatga tttttccttc catcatcatg atcagacgat
     1681 tgccatgtgc aatagcgtcc ttcatgttgt gggtgatcat caatgtcgta aggtgatcgc
     1741 ggtttacgat catatctgta atttccagaa ctttggcagc tgtttttgga tcaagagctg
     1801 cggtatgttc gtccagaagc agaagctttg gtttctgaag cgttgccatc agaagagtaa
     1861 gagcctgtct ctgaccaccc gagagaagtc ctactttaga agtcagtctg tcttccagac
     1921 caagaccaag aattttcagg agctctttgt attcttcgcg ctcagcttta gtgattccgg
     1981 agcggagaag acgggatttt ccgcggcgtt ttgcaagtgc aaggttttcc tcgataccca
     2041 ttgttgcagc ggttcctgtc attggatcct gaaacacacg tccaaggtat gtagcacgtt
     2101 tatgttcaga aagttttgta acatcaatat tatcgataag aatctgtcct tcatcaaccg
     2161 gccaggttcc tgcaacagca tttagcatag tagatttgcc ggcgccgttt cctccgataa
     2221 cagttacaaa atcgccttcg ttcagcttca ggttcagacc atttaatgca cgtttctcat
     2281 taatggttcc gggattaaag gttttataga tatttttaag ttcaagcatt tttatttacc
     2341 tccccttttg gctggtttat taaagtattt gcctttccag tatgggaatg caaggaagag
     2401 agcaactacg attgcggaca gcatcttcag caggtcagtg tcgataccca tccagataac
     2461 aatctgaagt accagataat acagaatgga accgaagata actgctaaca agcgaagggc
     2521 aaagttgcgg aaaatacgtc caaagattgc ctcgccaata ataactgctg ccagaccgat
     2581 aacgatggaa ccacgtccca tgttgacatc tgcaaatccc tgatactgtg caaggagtgc
     2641 actggaaagt cctaccagac cgttggaaat cataagtccg agaactttat tcctgtttgt
     2701 gttgataccc tgggcgcgtg acatatttgg gttacatccg gttgcacgaa gggaacagcc
     2761 aagctctgtt ccaaaaaacc agtagagaat ggcaatcagg agaacacaca taactgctac
     2821 aataaaaatt gtgttttggg aaagagatgc attttttata tgtcgcaggg aaaccagaag
     2881 attatattta tcaacgttga ttgcctgatt tgcttttccc atgatcttca ggtttacgga
     2941 atacagagat aactgtgtca ggattccggc aaggattgcg ggaattccca taaaggtatg
     3001 aaaaattccg gttacaaggc ctgccagcat tccggcgaga gtagcggcca acatggaaat
     3061 ccagacatta tgaccggaaa gcatcatcat aatacacact gcaccaccgg tgcacatggt
     3121 gccatcaact gtaaggtctg caatatccag aatgcggaaa gtgatataaa caccgattgc
     3181 cataattccc cagatcagac cctgggctac tgcacccgga agtgcagtga ttaatgttat
     3241 aatttgcatt tgtaatttcc tcctgttgag acgcgaaaag cgagagaggc gtcaaacctt
     3301 tcccgctgat cgcatataaa ttgaattttt tataactgtt tgataagctg ttactcaaaa
     3361 tcctgttgct gtgagtattt ttcaactgtc tgaccggatt tatctggcag cttcttcagt
     3421 tgtgttatct tctgatgttt catcagaaga tttgtctgat gcctctgcat catcagaagc
     3481 ctcttctgtg tcttcagcag cctcaccgat tgcaacataa tcatccggaa cttcgatgcc
     3541 cagctctttg cagatatctt tgttatattc ttttgtgtag tttggtgcat attcgatcgg
     3601 cattgtggaa atatcttcac cgtcttttaa aatcttaaca gccatcttac cggttgtaac
     3661 accaaggtca taatagctga tggaaagtgt tgcaacacca catccgctgc agataccttc
     3721 ttcacctgtg attaccggaa cttttgccgg aaggcagatg ttgttgataa tctctgtgtt
     3781 ggaagcaact gtattatctg ttggtacata aattacatca cttgcgtcag cagcggttgt
     3841 aacaacagaa gagagatcat tagaatcaga gaatgcatag tattcacatg tatatccgag
     3901 tttttcaagt tcagctttta ctgtatctac ctgatactga gagtttgcct cggcagaaca
     3961 gtagagaaga cctacatttt ttgcatccgg gaaaagttca ttgagcattg ctgcctgctg
     4021 atcaagggga gcaaggtctg cagttccgga aatatttccg cccacagttc cgtcgaaatc
     4081 atccagtcca agtgcaacac cgtattcagt aacagaagta ccaagaatcg gaatatcgct
     4141 tgttcctgct gcagctgcct gaagagcagg agttgcattt gcaagaatca ggtcaacatt
     4201 attggaaacg aagctgttaa tgattgtaga acaggtgttg gaatctccct gtgcgttctg
     4261 ctcgtcaaag gtaacggcat cctttcccag ttctttggtg acttcatcct tgaatccctg
     4321 tgtcgcagcg tcgagagctt cgtgctgtac aagctgacag ataccaattg tatatttgtc
     4381 tccgtcagca gcacttgctg ttactgcgca ggttcccata gccatggctg ctgcaagagc
     4441 gattgctaat gtttttcttt tcataatgat atatcctcct aatataatgt ttaaattaag
     4501 tcaggtaaga attgcgttta ttatttgata atatgaaact tacctgaacc cgaatgattt
     4561 tctgcaggga aagcagtact ggtaaatgat tcggataatg tcatcgagtt atttgactat
     4621 gacgttttaa agtataacgc tttagcgtga aaaagtcaag cgacctgcac aattatattt
     4681 ttaattcata tagtataaag agtatatgaa gaaagcagag tgtcgtcatg gcatattcga
     4741 tcatgctgga tgccggacat ggaggtcagg atccgggagc cgtatataag ggaagacagg
     4801 aaaagaatga caatcttaaa cttgctcttg cggtaggtga gattttaaaa aataaaggga
     4861 ttgacatctc ttatacccgt accggtgatg tatatcagac accttttgag aaggcacagc
     4921 ttgcaaatca ggcaggagta gattacttta tttcatttca ccgaaacagc agtccaaagg
     4981 aaaatcagta taatggagcg gaagttctga tttatgataa aagtgggatt aaatatcaga
     5041 tggctgagaa tattctggga gctctgggag aagtgggatt ttgcgaaatc ggtgtaaaag
     5101 agcggccggg acttgtggtc ctcagacgaa ccaggatgcc ggctctttta atagaaaccg
     5161 gatttatcaa ttccgaagaa gataataaac tgttcgataa caagtttagc gatatagctc
     5221 agggaattgc agatgcgatt cttggaagcc tggatgagga aacagtgcag gaaccgcttt
     5281 attacagagt gcagactgga gcgttcagaa aaaaagagaa tgcggaccat atgttatatc
     5341 agttactgga aaaaggttat ccctctttta tgttacatga aaccggattg tataaagttc
     5401 agacaggtgc ctatcagcag attggtaatg cggtaaatat ggagcagaga ctgagggatg
     5461 acggttacag tacggttatt gtgacaaaat agccttctgg aaatattgga agtctgcgga
     5521 ttttttgttt aaccgaatca aataagtccc ctgcggaggt tgcgaaaagc aataagtagt
     5581 gggggacata gttttaagaa ttaacttggt tgtactttaa cagaaaaaat atggtacact
     5641 gtatctgtct atagaaatcc catagaaatc ctcgtaaata atgcatattg ttccggctca
     5701 tcagaacgta aaattctgtt ggactgtctc aaatgcatta tttgagaggt gctgtagaaa
     5761 aaacagataa cgaggagtta gtaatgatga atgacgtata tgaaaaattt ttaaaaagtt
     5821 cagaagagtt tatttttgca gaaaacaagc cggaaaaatc tgatattatt tttgttcccg
     5881 gaaatagtta tccgcagatg gcggaaaaag cagcagaatt gtttaagaaa gggatggcgg
     5941 actggattct gcccagtgga aaatacagcg tagtaaatgg aaagttttca ggcgttcttg
     6001 aaaaaagcaa tgtatatgat aaagaatatg gaacagaatg ggaatttctc agggatgttc
     6061 ttacaaaaaa cggagttccg gatcagaaaa tcctgaaaga agatcaggca acctttactt
     6121 atgagaatgc aatttattcc agacaggtga cagatcatgc gggactggaa atagaaagag
     6181 cgattttgtg ctgcaaatct taccatgcaa gaagatgtct gatgtattat cagcttttgt
     6241 atccggaaac agagttttat gtggtgcctg tgaatgcaga tggaattacc agagaaaact
     6301 ggagaaagaa cgaagaagga attgatgcgg ttacaggaga actctccaga atcgtgaaac
     6361 aattttcact gatgctggag agatgacagt tacggctgtt cttctgtttc ggttttcttc
     6421 tcgggaagcc agatgtggac aagttcgatt ctgtttttgt ccagacggtc aacaaccagg
     6481 cggatgccac tttcaagtgt gacagactga ccctctttgg gaaggcagtc aagctgttca
     6541 ataatatatc cgccgataga atcataatct tcagattcca gattaatatg gagggcttcg
     6601 ttgatatcat ccagcttggc agaaccctga acaacatatt ctctttcagg ctggatttct
     6661 ttaatatctt cgacttcatc ctcatcgtat tcgtcgcgaa tctcacctac gatctcttcc
     6721 aacagatctt ccaatgtgac cagaccggct gtggcaccgt attcgtccag aacgattgcc
     6781 agattgacgg atgctttacg catttcaatc atcaggtctg ctgtagcttt gtattcatag
     6841 gtaaaataag gctcacgcag gatgttgcgg attgaaaaag gtttgtcctt tggataaaca
     6901 agaagatctt tcatattgat aataccgatt acgttatcag tgttgtcctc ataaaccgga
     6961 aaacgggtat gcatatcttc attgaagacc gccataagtt catcatagga aaaattgata
     7021 tctataaagg tcatgtcgat tctgggaatc atgacatctt ttgcagttga atcgccaaaa
     7081 tcaaacacat tgtagatcat ctgtttttct tcgttttcaa tgacgccgtc tttttcacct
     7141 acattgacga gggtacgcag ttcatgttca gtcatggcat ttgccttttc gtccgggtta
     7201 acatgcagaa tgaccagtac accttctgtt attttattta caataaaaac aacgggagta
     7261 aggagaatca taagtccgta tattattctt gaataggcca gggacaattt ctctgcatgg
     7321 attgttgcca ggttttttgg ggttatctcg ccaaaaataa gaatcaacag agtcagaatg
     7381 ccggttgcga ttcctacata tgcgtttccc agaatcttta tggtgagtgt agtcatgaga
     7441 gaagaaacag acatatttac aatgttgttt ccgattaata cggtactgag catctttgga
     7501 gaatcggaaa ttattttttc cagaataaca gcacgtttgt tgccctgctc ggcaagagac
     7561 tgtatccgaa ttttatttac ggttgtcata gcggtttccg cagaagaaaa aaatgaagaa
     7621 agtgcgatca gtatcagaat cgccaccgcc tgaaaggcaa tacttgaatc caagatttat
     7681 tcactccttt tgattatttt tttattgatt gaatcatatc ataaaacatt taagcaaaat
     7741 atacatgatt tcatataaaa aatcaagaaa aagcttttgg ttcaaagata gtataaaaaa
     7801 atttaaaaga ggactgtcga aaaagtaaga tttgtgttat aattcactcg attaaaatga
     7861 aaaaaaacat tacagaatat ttacaaaatg ataaaagttt gataatatac agatatgtaa
     7921 tattattgta ttacgtaaaa aagaactgat atttggctga aagtaaaaaa ataattatca
     7981 ggaaacataa aaatcgaata taaatataga ggtgcgatat gtccaataat ataactagaa
     8041 taagaaaaaa taaattaaaa ggaacgggta tttttgcggc agcggcttta acggcggctt
     8101 tgattgcagg aaataatgta ccgggtgtaa taagacaggt cagtgcggct gagtcacagg
     8161 agaatactgt atcttctctg attccggata acatcacgct tgataagcct gtagaacttg
     8221 cgaatgtaga acttccggca acggaatatg gaacttttga atgggcggat ggaagtttcg
     8281 ttcctgcaca gcgtgtacag agctgtgagg tacttcttat accggcagaa ggacaggatt
     8341 taagccatgt ggatggatgg gatccggaga gcggcgcggt tgtcggttac atcaatgtaa
     8401 tagtgaacag tattacggat ggtgataatt ctgataagac agaaggctca gataaaacag
     8461 atccaacaga aaatgcagat ccaacagaaa cgcctgaaac ttcgtcagaa aaacctgccg
     8521 cagatgaaaa tgctgataca gacaataaag aagataagga aagtaaatca gatcaggata
     8581 ataaaactga tacagacaat gaagagaata agattgaaga agataaaaca gataataaaa
     8641 acaacaaaga taataacagc aatgcagata agacggataa agatacagaa actaccggta
     8701 agctggaacc tgcagatgat atgacacagg ataaagaaga tacgaagaaa gatgatgaag
     8761 atggcgcaga tgataatatc tttgataatc ctgttctgcc ggacgataag gatgaccgtc
     8821 ctacagatgc agaggagtct ctttctgatg aagaaaaaga agagagggcc gcacttaatc
     8881 atacctgcga cggtattaca gtaagcggag ttaatcttcc atggtatgta cagttcagag
     8941 tttcaagcgg tgacagctat cagtttacca atgaatcaga tgcaatgatt ttccagtctt
     9001 atgaatttga actctgggat cttaagaata atacagaata tgagattcct aatggagatt
     9061 atatcagtgt cactgtgccg gtaaaatccg gatatcagta tactatcgaa catctcctgg
     9121 ataacggggc aactgagacg attgttccga gtgtagagaa tggtattatg gtattcagca
     9181 cacattcttt cagcccattt ggaattgcag gaagcagaca attggtaggg cctgatacag
     9241 gaaatgatac ggacgacaca gatgcggtaa ctcctgcacc ggcttcctcc gacagtcaga
     9301 gttctgattc cggaaagaac aatacagtat ctatgaatga cagttctgac agcaataatg
     9361 gttcttcttc tgatcagaat gataattcaa cggaaaataa agctgtgaaa aataacaata
     9421 cagtaaatac cggagataca acatcaatta tgccgtttgt gatactgttt gtggcagctg
     9481 cagtgatcgc cggtgtggtt gtatttataa aaaagagaaa gaaatagaag aataacactg
     9541 attcctcccc catatagttt aacaggaggg gaagcaatga aagtcagagc aattttgaaa
     9601 tcactattat ttgcatatgc attaacagga gtggcattac tgcttttggc cctggtactg
     9661 tttgcttttg atctgggaga aacagctgta gatgcaggga ttatcataat ttatgtactt
     9721 gcatgtttca tgggaggttt tatggcaggc agaattgtgc gtaaagacaa atatctctgg
     9781 ggcgttatca caggcctgac ttattatgtt ttactgttga ctgtctctgt tatggcaaaa
     9841 ggtggttggg atatgagtgc agctcatgca gttacaacat tttttatgtg cacaggcggc
     9901 ggaacactgg gtggaatgct gtcataaaaa aaagctttca aaatgaaaag atatatgata
     9961 tactatgcca agaatataat tacataagga ggatagagtt atggaacata tcaaaaccct
    10021 gaatacaaag aatttacaga acactgtaaa aaaaggtgga tgtggcgagt gccagacttc
    10081 ctgccagtcc gcatgtaaaa cttcctgtac agtaggaaac cagagctgcg agcagaaata
    10141 agatcagcta tggagaaatg agataagcag cggaactttt attccgctgc ttatcttacg
    10201 cttagaaagg attttagtaa aatgagtctg attcaccgtt ataaaagcaa tggctttaat
    10261 attgtactgg atatcaacag tggatgcatc catctggtag atgaggttac atatgaggtt
    10321 cttccatatc tggaaaaggg ccttgacaca gaagctattg cagagaaact ggaaaacaaa
    10381 tataacagag aagatattga gacatctgta aaagaatgta ataagctgaa agaagatgga
    10441 atgcttttta caaaagatgt ttacgagaat gtaattgaag aattttcaaa taaccggcag
    10501 accgttgtaa aagcattgtg cctgcacatt gctcatgact gcaatctggc ctgccgttat
    10561 tgttttgccg aagaaggcga atatcatggc agaagagctc ttatgtccta tgaagtcggc
    10621 aagaaagctc ttgatttcct gatcgcgaac tccggttcca gaaaaaatct ggaagtagat
    10681 ttctttggcg gcgagccgct gatgaactgg caggttgtaa aagatctggt aaaatatggc
    10741 agagagcagg aaaagcttca caataagaaa ttccgtttca ctttaacaac aaacggagtt
    10801 cttctgaacg atgaagtaat ggaattctgc aataaagaga tgggcaacgt tgtactcagt
    10861 gtggacggac gtaaggaagt acatgactac atgcgcccat tcagaaaagg tgcagggagc
    10921 tatgatctga tcatgccgaa attccagaag tttgcagaat ccagaaatca ggataaatat
    10981 tatgtaagag gtacttttac ccaccataat cttgatttct ccaaggatgt gcttcatctg
    11041 gcagaccttg gattcaaaca gatttccgta gagcctgtag ttgcggctga tacggaggaa
    11101 tatgcgatcc gcgaggagga tatcccgcag atcatggaag agtatgacac tcttgcaaaa
    11161 gaaatgatca aaagagagaa agagggaaaa ggatttaact tcttccattt tatgatcgac
    11221 cttacaggtg gtccttgtgt atacaagaga ctgtcaggct gtggttcagg aacagagtac
    11281 ctggctgtaa ccccctgggg tgatttttac ccatgtcacc agtttgttgg tgaagaacag
    11341 tatctcatgg gaaatgtaaa cgaaggtatc acaaagccgg aaatccagaa agaattcggc
    11401 ggatgcaacg tttacacaaa gaaagactgc aaagactgct tcgcacgttt ctactgtagt
    11461 ggcggatgtg cggcaaatgc gttccatttc cagggagata tcaaaggcaa ttatgaaatc
    11521 ggatgcgaac tccagagaaa acgtgtggag tgcgccatca tgataaaagc cgcactggca
    11581 tgtgattagt ggacaggaat ctgtctgact gataccgctg tcggctgtta tcataacaga
    11641 aaatggctgg caggcggatg aacatgaccg cggacaaaaa atcaagaagg gaaaagaact
    11701 atgaagaaaa gtaaaggaat cgtagtgctg cttctgacac tgatcctgac tgtgttcttt
    11761 tgctttactg cagccgtagg tatcggtcct accggaaccg gtgcagcaaa acacatcaac
    11821 acaggtcttg atcttgccgg tggtgtcagc attacctatc aggctaagga gagcaatccg
    11881 acaagcgaag agatgtcaga tacgatctac aagcttcaga agcgtgtaga gcagtacagt
    11941 actgaggctc aggtatacca ggaaggatca gaccgtatta cagttgaaat tcctggtgtt
    12001 acagatgcag atactattct gaatgatctg ggtaaaccag gttctctgta tttcatcaca
    12061 aaagaagatg ctgacggaaa ccagaacttt actaccggcc aggatggata tgttctctcc
    12121 aggactatgg atgagattaa ggaatccgga agtgttgttc tggaaggttc tgatgtagca
    12181 gatgcccagg gtggtgcaat ccagaatcag ggcacaagtg gaaaggaata tgtggtaagt
    12241 cttactctta cttctgatgg agaaaacagt ggtaaaacaa aattcgcaga agctacaaag
    12301 aataatgtag gcaagcagat cgctatcgtc tatgataata acattatcag tgctccgaat
    12361 gtaaatgaag agatttccgg cggaaaagca cagatcagcg gaatgtctga cctggaagaa
    12421 gcacagaacc ttgcttctta tatccgtatc ggttctctgg gactggaact ggaagaactt
    12481 cgttccagtg ttgtagctgc acagcttggt gaagaagcaa tctctacaag tgttcttgca
    12541 ggtgcaatcg gtctgatcat agttatcatt tttatgatca ttgtataccg tgtacctggt
    12601 gtagttgcag gcatcgcact gattctttat acatcattaa tgctgatcac gctgaatgcc
    12661 tttgatatta ctcttactct tccgggtatt gcgggtatta tccttggtat cggtatggcg
    12721 gtggatgcca atgttattat ttatgcccga atcagagagg aaatcggcgc aggagtttca
    12781 gtaaggaatt ctattaagtc cggtttcagc aaagctttct ctgcaatctt cgatggaaat
    12841 atcacaacgc tgatcgcagc ctttgtgcta atgtggcttg gttcaggtac tgttaaggga
    12901 tttgcttata cacttgccct tggtattgta atctccatgt ttacagcact ggttgtatcc
    12961 agattggttg taaatgcact ttatgcagtt ggtgtgcgtg atccaaagtt ctacggatct
    13021 gcaaaagaac gtaaggcagt tgattttatt ggaaagaaga aagtattttt tattatttcc
    13081 attatcctga tcctctgtgg cccggcagcg atgtttgcta attcacatgc aggaaacaaa
    13141 gcattaaatt acagtcttga gttctcgggc ggtacttcta caactgttac atttaatgaa
    13201 gatatggata tcaagaccat tgattctgaa gtaactcctg ttgtagaaaa ggtgacggga
    13261 gataaaaatg ttcagcctac aaaggtagtc ggaacaaatc aggttgttat caagacacgt
    13321 tctctgaatc agagcgagcg tgaagctctg cagagtgcac tggttgagaa atttggtgta
    13381 gatgacagca caatttccac agaaagcatt tcttctacag taagtagtga aatgcgtcgt
    13441 gatgcaatcg tagccgttat agtagctaca atctgtatgc ttctttatat atggttcaga
    13501 tttaaagaca tccgttttgc aagcagtgct gtattagcgc ttctgcatga tgttctggtt
    13561 gtacttgcat tctatgccct tgccagagta tctgtcggta atacatttat tgcctgcatg
    13621 cttacaatcg taggttattc tatcaatgct acaatcgtta tctttgaccg tatacgtgag
    13681 aaccttcaca gtagttccag agagaaactg gcagaagtcg taaatacaag tatcactcag
    13741 actcttacaa gaagtattta tacttctttt acaacttttg ttatggtagc tgttctttat
    13801 atcatgggtg tttcttctat ccgtgaattt gcagcacctc tgatggttgg tgttcttatc
    13861 ggtgcatatt cttctgtatg tattacaggt gcattgtggt atgtaatgaa aaagaaattt
    13921 acaggaaaag gacagccggc aattgctgca gcttccacat ccacaaagtc ctcttcaaaa
    13981 ccgaagaaaa cacgtgatgt atcacagaaa gatccgactc agccaaagaa gaaaaacaga
    14041 aaaagagtag ctgaacgtct ggctgccgaa gaatcagcta agaaacagca gaatgatgat
    14101 gctgaataaa agttactgtt cactccgttc acagtaacaa ataaaacaat aattgtctgg
    14161 aaaacaggca gacagaaata tcccggggta aaactccggg atatttttat gaggagagaa
    14221 aatatatgga aaaatgggta atagctgcaa aaagagcaga ttttaatcag atcggtcaac
    14281 agtttcatat tgatccggtg attgcgagag taatcaggaa cagagatgtg atcggagaag
    14341 ataagataag agagtatctg tcaggaacag tacaagagct tccttctccc tggctgatga
    14401 aagatatgga aaaagctgta gatatcctgg agagaaaaat atcgcagaaa gcaaaaatcc
    14461 gtattattgg tgattatgat attgatggtg tgacctctac atacatttta atgaaaggtc
    14521 tcgcaaggat tggagcagat gtggatactt acattccgga cagagtttca gacggatatg
    14581 ggattcatgc acatcttata gaaagagcag aaacggatcg aatcgataca atcgtgacct
    14641 gtgataatgg aattgctgcg gctgccgaaa tccagatggc aaaggataag aaaatgacag
    14701 tgattgttac agatcatcat gaggttcctt acagggagga aaagggggaa cgccggatgg
    14761 tgcttccgcc ggcagatgcg attttgaatc caaaacaata tgattgtcca tacccgaata
    14821 aaaacctgtg tggggcagtg gtggcattta aatatattgc agcactctac gagagatctg
    14881 gtgttccggc agaggagctg gaagattatt atgaactggc ggctattgca acagtaggag
    14941 atgttatgga tcttcaggga gagaacagga ttctggtaaa agaagggctg tgtcgtctga
    15001 aaaataccaa aaataaagga ttgcaggaac tgatccgcgc aaattctctg gaagatgcta
    15061 aaattacagc ttatcatatc ggatttgtgc tgggaccatg tatcaatgcc agtggcagac
    15121 tggatacagc ttcccgttct cttgcgcttc ttaatgcaaa aacaaaggaa gaagcagcaa
    15181 ggcttgccgg agatcttaca gctcttaatc agagccgaaa agctctcact gagaaaggaa
    15241 aagaagaggc aatccggatc atagagacta cagagctgaa aaacgacaga gtactggtag
    15301 tttatcttcc ggattgtcat gaaagtcttg ccggtattat agcaggcagg atcagggaaa
    15361 aatatcacaa gcctgccttt gtgctgacgg gcggtgagac aagcgcaaaa ggaagcggaa
    15421 gatcaataga aagttactcc atgtatgaag aactgataaa gtgtgcagac ctgatgatac
    15481 agtttggggg ccatcctatg gcagcaggcc tttctataga agaaaaaaat atagaggaat
    15541 tccggagatg tctcaacgta aactgtacat tgacggacga agaactgcgc cctaaggtcg
    15601 tgattgacgt accgatgcct gtgtcttatg tcacaaaaga actggtagaa cagatttcac
    15661 ttctggaacc ttttggaaaa ggaaatacaa aaccggtctt tgcacagaaa aatctcagag
    15721 tgcttgatca cagtattatc gggaaaaata aaaatgcagt aaaattaaaa ctccttgatc
    15781 cgcagggaat ctcagtggaa ggcatttatt tcggagaagc ggaggaattt gtgaacttta
    15841 tcagggaaaa agacagtgtt tctgttactt attatccgga gatcaacaga ttcaggggac
    15901 gagagagtct tcagatcatt attcagaatt actgttaaca ttaccgcctg ttttgtatct
    15961 gccggtaagc ctggaaatac aaatgtcatg gtttaacagt aacttgattc taaaataaaa
    16021 aggtgatata ctatagaata tttatgaatg aacagcaata taacacacac tggaggagaa
    16081 ataaaatgaa gaaaattgaa gattatgtat taagtatacc ggattttcct gaaccgggga
    16141 ttattttcag agatattaca agtgttctgc aggatgcaga tggcctgcag cttgcaatcg
    16201 actccatgca ggactgcctt aaggatgtag atgtggacgt gattgcagga acagagtcca
    16261 gaggttttat ctttggtgta ccgatcgcat ataatcttca taaaccattt gtaccgattc
    16321 gtaaaaaagg caaacttccc cgcgaaacag tatctgtaag ctatgatctg gaatatggca
    16381 gtgcagagat tgaaatgcat aaagattcca taaaaccagg tcagaaagta gttatcgttg
    16441 atgatctgat cgcaacaggc ggtacgatcg aagcagcgat caagctggtg gaacagcttg
    16501 gcggtgaggt tgtcaaggtt gtatttctca tggaacttgc aggtttaaaa ggacgcgaaa
    16561 gactgaacgg gtatgacgta gcgtccgtaa tttgttatga tggtaaataa gcacagctga
    16621 ttgtgcagga caggcaggtg ggagcatatg acagagataa caagaagtac agaagcaaaa
    16681 aaagatgaaa tgcagattga gaaagaaaaa ctggaatctg taaagagagc agatgcggca
    16741 gtaaagacca tgcatgattt tacaagtccg gaggtgcttt ataaagaact gataaacagt
    16801 gttctgaagt atcatccatc aacagatatt tccatgatag agaaggcata taaggttgca
    16861 agtgaagctc atgaaggaca gaaaagaaag tcaggagagc catatatcat tcatcctttg
    16921 tgtgttgcca tcattctggc agatctggaa cttgacaaag aaacgatagt tgcaggtctt
    16981 cttcatgatg cagttgaaga tacctggatg acctatgagg aagtggagaa ggaatttggt
    17041 tcagaggtcg cacttcttgt ggatggtgtt accaagctgg gacagttatc ttattctgca
    17101 gataaagtag aagttcaggc agagaacctc agaaagatgt ttcttgccat ggctaaggat
    17161 atcagagtta ttctgatcaa gcttgcagac cgtcttcata atatgcgtac cttacagtat
    17221 atgcgtcctg aaaagcagca ggaaaaagcc agagagacca tggatattta tgctcctatt
    17281 gccatgcgtc tgggtatttc caagataaag gtagagctgg atgacctgtc gctgaaatat
    17341 cttaagccgg atgtatatta tgacctggtg cagaaggttg ccctgcgtaa aagtgagaga
    17401 gaacagtttg taggtgcgat tgtaaaagaa gttaagaaac atatggatga tgctaatatt
    17461 aaggcacagg tggacggacg tgtaaaacat tttttcagca tctacaagaa gatggtaaat
    17521 caggataaga ctattgatca gatttatgat ttatttgctg tccgtattct tgtagataca
    17581 gtgaaggatt gttatgctgc ccttggtgtg atccatgaga tgtataagcc gattccggga
    17641 cggtttaaag attatattgc catgccgaaa cccaatatgt atcagtcatt gcataccaca
    17701 ttgatcggac ctaacggaca gccctttgaa atccagatcc gtacttatga aatgcacaga
    17761 actgcagaat atggtattgc tgcacactgg aaatataaag agtcgtctga cggaaaggtt
    17821 cctgtaggta agagtgagga agagaaactg aactggctgc gtcagattct ggaatggcag
    17881 agagacatgt ctgataacaa agaattcatg agtcttctga agaatgacct ggatcttttt
    17941 gcggacagtg tttactgttt cactccacag ggagatgtta aaacacttcc aagtggttct
    18001 acaccggtgg attttgcata cagtgttcac agtgcagttg gaaataagat ggtaggtgcc
    18061 agagttaacg gtaagctggt tccgattgaa tatgagatca aaaacggtga ccgtattgag
    18121 atcattactt cccagaactc tcagggacca agccgtgact ggctgaaact ggttaagagt
    18181 acgcaggcaa agaacaagat taaccagtgg ttcaagaagg aattaaaaga agataatatc
    18241 cttaagggca aggagatgct tgcgcagtat gcgcgtgcaa aggggtttaa gatcacaaat
    18301 tatacaaaaa cccagtatct ggaggccgtc ttgcgtaaat atggtttcag ggactgggat
    18361 tcagtacttg cggcaattgg tcatggcgga ctgaaagaag gtcaggtttt caataagctg
    18421 gtagaggcat atgataagga aaataagaag aatctgacag atgagcaggt tcttgaagct
    18481 gcttctgaga cacaggagaa gcttcacatt gccaagagta agagtggtat tgtggtaaaa
    18541 ggaatccatg atgtggcagt ccgtttttcc aagtgttgta atccgatccc gggtgatgag
    18601 attgtaggct ttgttacaag aggacgtgga atcacgatcc atcgtacaga ttgcgtcaat
    18661 gtgctgaata tgtctgagac agacaggaca cgactgatcg aggcggaatg gcagcagcct
    18721 gataccaagg aaaaagaaaa gtatatggct gagattcagg tttatgcaaa taaccgtaca
    18781 gggcttcttg tggatctttc caaaatattt acagaacgta agattgacct gcgaagtatc
    18841 aacagccgta caagcaagca ggagaaggca actatttcca tgagctttga gattggaagc
    18901 aaagaggaac tgcgttccct gatcgagaag atccgtcagg tagaaagtgt cattgacgta
    18961 gagagaacta caggctgatc atggtaaaat ctgttggaac attattttat ggaactgctg
    19021 cagattgaca gaaaggaata acatgaagaa tttagaatta cagaaatgta tattaggacc
    19081 tgtatataca aattgctatc tcctcaagaa taaagaaacc ggagaactga ttattgttga
    19141 tcccgcagat tgtccggaga agattgaact gaagatttcc cggatgagtg gaaaaccggt
    19201 ggcgattctt cttacccatg gacatttcga ccacattctg gctgcacagg cagtaaagga
    19261 gaaatataat attccgattt atgcctgtcg tcaggaagag gagatgctgc gcgaaccctc
    19321 gattaatatg actgtacatt atggacgggg atgttctatt gtgccggatg tatttctgga
    19381 ggatctggat gttatcagaa tggcgggatt ttctgttcag atgatccata caccgggaca
    19441 taccaaagga agctgctgtt attatctgaa agatgaaggc gtattgttca gcggtgatac
    19501 agtattctat ggttctgttg gaagaacgga ttttccgggt ggaagtacag cagaaatcgt
    19561 gaaaagtctc cataaactgg tagattcgct tcctgaagag accgaggttt tccccggaca
    19621 tgatgcatct accactattg gttatgaaaa gaggtataat ccatttgtgt aaaataggca
    19681 ttctgtttga gaacagagat tttgaacatg atgtttatga actgatcaaa gcgttttatc
    19741 ccgaagcgga gatacatact ctttatgaaa atgctgaagc agagtatgac ctccgcttca
    19801 gtgtggaacg ggataatgac agttatatca taaaatacga aagggcagag aatctgtcga
    19861 aacaggagac agagcaaaaa ggggtaattt ccgcagacat actttctaaa gagaatgcag
    19921 gctgtggaat acaggatgct catgctctga gaaaagagaa taaagatact atcaaatatg
    19981 ctctgtatca gttgttggta aaactgacgg gcagaactct tccatgggga aatctgacag
    20041 gaatacgtcc tgccaaactg gcaatgggaa tgatcgaatc cggaatgaaa aatacggaag
    20101 cagcccggga gatgcgtgag agatatctgg taagtccgca gaaaacagcg cttgccatca
    20161 ctattgcaaa cagggaaaga gagattctga aggatattga ctatgaaaat ggatacagcc
    20221 tttatattgg aatcccgttt tgcccaagta tctgtctgta ttgttccttc agctcctatc
    20281 cgctgaaagt gtgggagaag agaacagatg aatatgtgga agctctctgc cgggaggtaa
    20341 gagagactgc tcttatgatg aagggaagaa aactggacac catctatatt ggcggcggta
    20401 ccccgactac actgcttcca catcagatcc gtaagctcct ggatacagtg ggagaagctt
    20461 ttggctatga aggactggca gagtttactg tggaagccgg cagaccggac agtattacac
    20521 gtgaaaagct gatgacgatc agggagtatc cggtaacaag aatttccgta aatccacaga
    20581 ccatgaatca ggaaaccctg gatattatcg gccgcagaca tactgtggag cagacaaaag
    20641 aagcgtttcg tctggcaaga gagctgggat acgataacat taacatggat ctgatcgtag
    20701 gtcttccggg tgaggatatt catatggtag aacgtactct tgaacagatt cgtgaactgg
    20761 caccggacag tattaccgta cattcactgg cagtgaaacg tgcagcaagg ctgaatattt
    20821 ttaaagagaa atatcaggaa atgtcttttg agaataatca ggagattatg gatctgacca
    20881 tgaaaacagc atatgaaatg ggaatgggcc cttattatct gtacagacag aagaatatga
    20941 agggaaattt tgaaaatgtt ggctatgcaa aggttgacaa agcgggaatt tacaatatac
    21001 tgattatgga ggaaaaacag cctatcatcg cactgggggc aggcggttct tccaagctgg
    21061 tctttgacca cggacagaga attgagcgtg tggagaatgt aaaagacgtt tccaattata
    21121 tttcccgcat tgatgagatg atcgagagaa aacggacagc aatagctacc tggctgtagg
    21181 atgtggaggt aacattttgg acacagtaca aaagacagcg gcaggttcac agcagaggat
    21241 cctggaattt gaccttgctt ctgaactgca tcatggaatg ctggtaagta atctggctta
    21301 tgcggttgcg gaggagatgg gactgacgca tgaacagtgc tatgagcttg caatggcggg
    21361 aatgctccat gatataggaa agctgaagct gacaagttat atcaacggac aggagcagga
    21421 tcctctggtg atcgaggaac tgaagtatgt ccggatgcat tctgcattgg gatatgagga
    21481 acttaaaggg cagggatatt cggattttgt attggagagt atcctgtacc atcatgagaa
    21541 ttatgatggc agtggatatc cgtccaataa agcaggtgat gacataccc
//
