LOCUS       c00013_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BFFJEIOL_13.
ACCESSION   c00013_gnlPro..
VERSION     c00013_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:24:23
            Original ID  :: gnl|Prokka|BFFJEIOL_13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 15521
            Orig. end    :: 38770
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[25521:28770]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             570..2078
                     /locus_tag="ctg13_16"
                     /transl_table=11
                     /translation="LRGHKWRLLGKVKNEWIKKGKEQKAMEEKNNTTVDIPENDGEFML
                     EPVPMSARRSTRSQFMVWIGFGYAVTGLIIGGTLGGYGGTGGMPPSQAMMAIILGMGAL
                     YLVTCFLGIVAQKTGLNLSLLARFSYGYKGSAIPMAVMALLTLGWFSSILGMIGDIWGA
                     FIGNPTGVIVFDPSKYGFSGVAPITLEVVIACVFWGLVFTFTAVKGMGAIEKVSDVFAP
                     LILIVAVVVGIIYVVQCGGVGGFLDKANKLHGLGMGEAITAVVGSWIAGAVMGVDMFRF
                     NKSTKAVWGCAAACFILTNPILNIVGYIGTVYIGNFNYVLWMLGVNFIVAILGVVVWTT
                     ALWTTDNSELYCNALYTGPSLNAFGINVSRKKLVIIAGVIGTVLGSFAFYQLFFANFIN
                     ILGSMAPPLCAPILADYFVIGRKNKDKYNMELLNKHPNFRWAGVISFAVGAILGFVFQY
                     KITLPLDLPSGLVAMVISFIVYIAIYKMTPDAAVDEKLVSGLEK"
     CDS             2075..3076
                     /locus_tag="ctg13_17"
                     /transl_table=11
                     /translation="MKRILLILTGGTIASVETEQGLRPGISEEELRESLSGITDFCQVE
                     ILSLLNVDSTNIQPEHWQMIVQAIEKRFDCYDGFVITHGTDTMAYTAAALSYMIQNPHK
                     PVVITGAQKPLVKTVTDARKNLRDSFRFACEENVNGVFLIFNGEVILGTRARKVRSKSF
                     NAFDSINYPIVAFIDNDRVIRYVDISGDSGPTSFYSHLVPKVFLLKLVPGITPDILDYI
                     SDHYEAVVIESYGVGGIPFADERNFLEKLECLNRKKCIVVIATQVMLEGSDVELYEVGF
                     RAMSRYHLLQAYDMTTEAIVAKLMWLLGKCNDFESFQKEFYTPVSCDLLRCE"
     CDS             complement(3155..4090)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg13_18"
                     /sec_met_domain="LysR_substrate (E-value: 1.2e-33,
                     bitscore: 107.4, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.3e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFEHYTYQKEQ
                     LLLAVPKNYSVNNRLQKYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4188..5630
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_19"
                     /sec_met_domain="Lyase_1 (E-value: 5.7e-95, bitscore:
                     309.4, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 3.1e-22, bitscore:
                     70.0, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGRITMKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITG
                     LNMHPEIINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIISGKFHNEFIVDPIQG
                     GAGTSLNMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRL
                     LQNLKKQLLRLYDALNKKAAEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRM
                     DKAMDEMRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPF
                     VAVSGAVKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVV
                     NQVAFNIIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGIT
                     ANEERCRYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELN
                     RILDPIHMTEPGISGKDYLIKK"
     CDS             complement(5738..7423)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_20"
                     /sec_met_domain="FTHFS (E-value: 1.5e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_21"
                     /sec_met_domain="OKR_DC_1_C (E-value: 8.8e-14, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 1.9e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_22"
                     /sec_met_domain="Spermine_synth (E-value: 2.7e-53,
                     bitscore: 171.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 1.6e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKAGYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDDLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_23"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.3e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 3.3e-36,
                     bitscore: 115.6, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKVDADNAEEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_24"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 6.8e-15,
                     bitscore: 46.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTRSSLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13197..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_25"
                     /sec_met_domain="PAD_porph (E-value: 2.6e-128, bitscore:
                     418.9, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRLSDISDTKTLRAGFPDICRAIKEKETDMEVTEKNRTKYRMPGE
                     FEPHEGCVMIWPERPGSWNYGAREAQKAFVKVAEAIGESENVYMLVSKAQMENAKNQLG
                     NVSGVTLLECETDDAWARDVGATMVLDEKEAVCGVDWQFNAWGGDFDGLYRNWEKDDRV
                     AAFICRTLGCPCLDARPFVLEGGSIHSDGEGTLIVTEACLLSQGRNPQMSREQIEEQLK
                     YWLGVHKIIWLPCGIYQDETNEHVDNVCAFVRPGEVVLAWTEDETDPQYAMSLADLKVL
                     EQETDAKGRKFKIHKLPIPQKPVCLTREDVDGFVFEEGEDEREAGERMAASYVNFYISN
                     GGIILPQFGDENDKRAVEILQKCFPERRIYPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14488..15366
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_26"
                     /sec_met_domain="CN_hydrolase (E-value: 3.2e-55, bitscore:
                     178.4, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYENYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15590..16051
                     /locus_tag="ctg13_27"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETEFPHQQEKRWKKVIDLS
                     TWHGRAVVIVAAAVIIILLILIIGVAIPFFIILAIILYFLSWLKKRNNQ"
     CDS             16273..20982
                     /locus_tag="ctg13_28"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIQAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCSAKAESIQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKSVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDEIPSCLQLLEGQYTVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQSITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGEAETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGAFIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEMVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEAYVKAKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKVT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYANSGGYSGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             20979..21866
                     /locus_tag="ctg13_29"
                     /transl_table=11
                     /translation="MKKFRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             21905..23149
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     105.5; E-value: 1.2e-32)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_30"
                     /sec_met_domain="Peripla_BP_3 (E-value: 6.8e-33, bitscore:
                     105.5, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNCYCLYITIPRGVLEKTNEKSLDILYNLCIKNNLFVRAYKLYPK
                     YRREEDMTDNGKPKYFSLMEQLRSDIVSGAIRPGEKLPSENELSQKYSLSRHTVRKALG
                     ILEQDGYVEAFHGRGTYCSENVRHIKNSKNIAVVTTYISDYIFPRLIQGMDNVLSVSGY
                     SIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDKFGIPYVFI
                     QGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERHKGYVKALQ
                     ESGIVYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQVMEELEKMG
                     VRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPEEESKVERL
                     IYPELIIRGSCRKIL"
ORIGIN
        1 aaatcaattt ttttactggc aatctgataa attttttcca gttcggaatc agatgcaaat
       61 cggattgcat attcaactgc tccgcattca agaatagaac ggtactggca tagctcctga
      121 agctctgaaa gagacagctt acggatcaga taaccctttc gagggatttt ttcaaggata
      181 ccctcctgac acaatatatt cagtgcttcc cttgcaggtg ttctgcttac ttgaaaacgg
      241 gatgagactt ctgcttctgt aatgaactga tcattatagt gtagattatt aatatcattt
      301 cgaagctgtt gcagaatggc ctctgtagta gaaaaatttt ttttattaac gtttggtatc
      361 atatatggac gctcctcaat aaaagataaa gaatgaaata aatgaattta aacacattat
      421 aaatgtaata tcagtaactt gcaactacgt atatcaccag aatactaaca aaaatcatag
      481 aaaaagattg ttactttcga cggtttttgt ggaaaattta gaaaattatt gacgcagatg
      541 tatttctgtg atatacatct ggtatacgtt tgcgcgggca taaatggagg ctccttggaa
      601 aggtaaagaa tgaatggatt aaaaagggaa aggaacagaa agctatggaa gaaaaaaaca
      661 atactactgt agatataccg gaaaatgatg gggaatttat gctggaacca gttccgatgt
      721 cggcacgtcg ttcgacccga agccagttca tggtatggat cggttttgga tatgcagtaa
      781 ccggtctgat cattggcgga actttaggcg gttacggtgg aacaggcggt atgccacctt
      841 cacaggcaat gatggctatt attcttggta tgggtgcact gtatctggtt acatgtttcc
      901 ttgggattgt cgcacagaaa acagggttaa atctttctct gcttgcacgt ttttcttatg
      961 gatataaggg aagtgctata ccaatggctg taatggcatt gctgacttta gggtggttct
     1021 caagtattct tggaatgatt ggtgatatat ggggagcatt catcggcaat ccgactggag
     1081 tgattgtatt tgacccatca aaatacggat tttccggagt agcacctatt acactggaag
     1141 tagtaatcgc ctgcgttttc tggggactgg ttttcacttt tacagcagtg aagggaatgg
     1201 gagcaataga aaaagtatca gatgtttttg ctccattgat tctgatcgta gctgttgtag
     1261 taggaattat ttatgtagtt cagtgtggcg gcgttggtgg ctttttggat aaagcaaata
     1321 aacttcacgg acttggcatg ggagaagcaa ttactgcagt agtgggaagc tggattgcag
     1381 gtgcggttat gggcgttgac atgttccgtt tcaataagag cacaaaagca gtctggggat
     1441 gtgcagctgc atgctttatt cttactaatc ctattttaaa tattgtagga tatattggca
     1501 cagtatatat tggcaatttt aattatgtac tttggatgct tggcgtgaac tttattgttg
     1561 cgattttagg tgttgtggta tggacaacag ctctctggac aacagacaat agtgaacttt
     1621 attgcaatgc tctgtatacg ggcccgtctt tgaatgcatt tggaatcaat gtttccagaa
     1681 aaaaactggt tattattgca ggagttatag gaactgttct tggttcattt gcattttatc
     1741 agctgttttt tgcaaatttc attaatattc tgggatctat ggctccgcca ttatgtgcgc
     1801 cgatccttgc agattatttc gtaattggaa gaaagaataa agacaaatac aatatggaac
     1861 ttttaaataa acatccaaat ttccgctggg caggggtaat ctcttttgct gtaggagcaa
     1921 tcttaggatt tgtattccag tataagataa ctcttccttt agatttaccg tcaggtctgg
     1981 ttgcaatggt gatttctttt atcgtttaca ttgctattta taaaatgaca ccagatgcag
     2041 cggtggatga aaaacttgtt tcaggattgg aaaaatgaag cgtattttat tgatattaac
     2101 aggaggtaca attgcctctg tagaaactga acaggggctg cgtccgggaa tctcagaaga
     2161 agaacttaga gaaagcctgt ctggcataac ggatttctgc caggtagaaa tactgtctct
     2221 gctgaacgta gacagtacta atattcaacc ggaacactgg caaatgatcg ttcaggcgat
     2281 agaaaagcgt tttgactgtt atgatggatt tgttatcacc catggtacgg atacgatggc
     2341 atatacagcg gcagctcttt catatatgat tcaaaatcct cacaagccgg ttgtgattac
     2401 aggagcacaa aaacctctgg ttaaaacggt tacagatgcc cgcaaaaatc taagagatag
     2461 ctttcgcttt gcatgtgaag aaaatgtaaa tggtgttttt ctgatattta acggagaagt
     2521 aatactaggc acacgcgcca gaaaagtacg ttccaagagt tttaacgctt ttgacagtat
     2581 caattatccc attgtggcat ttatagataa tgacagagta attcgctatg tagatatatc
     2641 aggtgactcc ggtccaacca gcttttattc ccatttggtg cccaaagtat ttcttttgaa
     2701 gcttgttccg ggaatcacac cagatatatt ggattacatc agtgatcatt atgaagcagt
     2761 agttatagaa agttatgggg ttggtggaat tccgtttgca gatgaaagaa attttctgga
     2821 aaaactggaa tgtcttaaca gaaaaaaatg tattgttgtg attgctacac aggtaatgct
     2881 ggagggaagt gatgtagaat tgtatgaggt tggattcagg gcaatgtcca gatatcatct
     2941 ccttcaggca tatgatatga caacggaggc aatagtcgca aagttgatgt ggcttcttgg
     3001 aaagtgtaat gattttgaga gctttcagaa agaattttat actccggttt cctgtgatct
     3061 cctgagatgc gaataaaaag ctattgataa agaaaagctg ccgtcttcac aagtaaaatc
     3121 tgtggaggcg gcagtttttg atatgtatga catatcagga aaagggcagc ttcaggaatt
     3181 cttccatggc tctgctgata tagcggcctt tcttccagta aaaaaataca gtgcgtttac
     3241 tgctctgacc gggcagctta taaaaaacaa gttctgaatt tgttggaact ctggagagca
     3301 gaagatcccc gatgaaagtg atacccattc ccaaacatgc aatattatag gcggtcatct
     3361 gttgatccag gcgaaatact acagaaggtg aaaagtgatt ttcctgacaa atggtcagtg
     3421 cacgcttacc ggtatcgtta tctgaacgaa gaataataaa tggttcgttc tcgaatttgt
     3481 ttaatggaac agaaggaata tgagaagaac ggaactgccc gttccggatt tcttcaatag
     3541 gaatctgata tttctgcagt ctgttattta ctgaataatt ttttggaacc gccagaagaa
     3601 gttgttcttt ctggtaggta taatgttcaa aaatctggtt atccaggata cagttatcga
     3661 ttaccagatc taactttccg gcctggagaa actgggatag ctttgctgta ctttcttcta
     3721 caagagaaat ttgaacatgg gggaattttt gggaaaaatc agcaataagg ggaggcagaa
     3781 tccacgaaga aaaaaagtta ctgccaccta cattaagagt tcctgttttg agatttccca
     3841 gatccagtag gtagttttcg agattatttt caatatccat gactttttca acagcctgta
     3901 tataatgttt tccgacttcg gttaattgta aaggtttggt acttcgatca aaaataggat
     3961 agccaatacg gttttccaca cgttttacat tggcgcttaa agaaggctgc gaaatgaaaa
     4021 gagcagcagc agctttggaa aagctttttt ccttgtatac ctcatagatg tattccattc
     4081 cttgaaacat ataaactcct ccgatatata acttaaacac tatatatttt ataaaaatat
     4141 atgtatttga ttatattata gcagagatat ataatgaggg caaatacatg ggagggcgaa
     4201 taactatgaa aaaaacagac tatcgtgtag aaagggattc tattggtgta aaggatattc
     4261 cggaagatgt atattatgga gtacaatcct tacgtgcggc tgaaaatttc cacattacgg
     4321 ggctgaatat gcatccggaa attattaaca gtcttgcata cataaaaaaa gcagcagcga
     4381 taaccaattg tgaggtgggg cttcttgaga agaaaaaagc acaggcgatt gtccaggcat
     4441 gtgatgaaat tatttcagga aaattccata atgaatttat tgtggatccc attcagggag
     4501 gagcaggcac atctttaaat atgaatgcca atgaagtaat tgcaaatcgc gcaattgaga
     4561 tactgggagg aaaaaagggc gattatacaa ttataaatcc taacgatgat gtgaattgtg
     4621 gacagtctac caatgacgtg attcctactg ccggtaaaat gacttctctt cgtttgttgc
     4681 agaatctgaa aaaacagctt cttcgcctct acgatgctct taataaaaaa gctgcagagt
     4741 ttgatcacat aataaaaatg gggcgtacac agatgcagga tgcagtacca attcgtctgg
     4801 gacaggaatt taaggcatat tcggtagcaa tcatgcgtga tatccacaga atggataaag
     4861 caatggatga aatgcggact cttaatatgg gaggtactgc tattggaaca ggaattaatg
     4921 cagatgaggg ctatctgaga agaattgttc caaatctcac tgaaatatcg ggaatggact
     4981 ttatacaggc ttttgatctg attgattcca ctcagaatct ggatccattt gtagccgttt
     5041 ccggtgctgt gaaagcatgt gcggtaactc tttccaaaat gtcaaatgat ctccgtctga
     5101 tgtcctccgg tccacgtact ggttttgggg agattaatct tccggcaaaa cagaatggtt
     5161 cctctattat gccaggtaaa gttaatccgg ttattcctga agtagtgaat caggttgctt
     5221 ttaatattat tggtaatgat gttaccatta ccatggctgc agaggctggt cagctggaat
     5281 taaatgcgtt tgagccgatt attttctatt gcatgttcca gtctatcgat actcttggct
     5341 atgcagtcca gacattggtg gataattgta ttgtaggaat tacggcaaat gaagaaagat
     5401 gccgttatct ggtagaaaac agtgtaggta ttatcactgc aatcagcccc catcttggat
     5461 atcagaaggc tgcggatatt gcaaaaaagg caattaagac aggcgaatct gtaagaagtc
     5521 tgattctgaa agaaaagctt atggacgagg atgaacttaa tcgcattctg gatccgatcc
     5581 atatgacgga acctggtatt tccggaaaag attatcttat aaaaaaataa gaaaaaaaca
     5641 ggcgggaaaa tcttcccgcc tgtaaaatcg tctggacaca tatcatatat aaatatgatt
     5701 tttatatttt tgaattattc gattgatttc aaccggatca gaacagacct gtgatcttac
     5761 ctgtctcgtc tacgtcgatt ctctcagcag ccggaacttt aggaagacct ggcattgtca
     5821 tgatctcgcc tgtaagagct acgatgaatc ctgcaccagc ggaaatcttc aggttacgta
     5881 ctgtaacttc gaagtcagta ggagcaccca gtttagtctg gtcatctgtt aagctgtact
     5941 gtgtcttagc tacacagatc gggcagttgc caaagccaag agcttctaac tgtttcgcct
     6001 gtttctgagc gttagctgtc agaactactt tcttaccgcc atatactttc tgaacgatct
     6061 ggttcagttt gtcttcgata gaaccttcca gttcatatgc ataggagaag tcgtttggtt
     6121 cttcaacaag acggataact tcttctgcaa gtttgattcc gccttcgccg ccttttgccc
     6181 atacttcaga aagagcaacg ttaacgccca gttctttaca tttagcttct acaaagtcaa
     6241 gctctgcttt tgtatctgta gggaatgcgt tgatagcaac aacacatgga agtttgtata
     6301 cgtttttgat gttggaaacg tgttttaaca ggttcgggat acctttttca agagcttcca
     6361 ggttttcatt gttaaggtca gccttagcaa cgccgccgtt gtatttcagg gcacgtactg
     6421 tagctacgat tacaactgcg cttggtttta agccagccat acggcatttg atatcaagga
     6481 atttctcagc accaaggtca gcaccgaaac cagcttctgt gattgcataa tcagcaagct
     6541 tcatggccat ctttgtagct gttacggagt tacatccgtg agcgatgttt gcgaatggtc
     6601 cgccgtgtac gattgcagga acgtgttcca gagtctgtac gaggtttggt ttcagggcat
     6661 cttttaacag ggctgtcata gcgccttctg cgtgaaggtc acctgctgtt acaggtttct
     6721 gttcggaaac tttgccgtat gtatatccga tgatgatctt ggataatctt tctttcaggt
     6781 ctttgatgtc acttgcgaga cagagaactg ccatgatttc agatgcaact gtgatgtcgt
     6841 atccgtcttc acgaggcata ccgtttgtct ttccgccaag accatctact acgttacgaa
     6901 gctgacggtc attcatatct acacatcttc tccatgtgat cttacgtggg tcgatgttta
     6961 atgcattgcc ctggaagata tggttatcga tcatagctgc cagtaagttg ttagctgcgc
     7021 caatggcatg gaagtcacct gtgaagtgaa ggttaatatc ttccatagga acaacctgtg
     7081 catatccgcc gcctgctgca ccgcctttaa caccgaatac cggtcctaag gatggctcac
     7141 gaagagctac cataacactc ttgccaagtc tctgcatacc atctgcaaga cctacagtag
     7201 tagtagtttt accttctcct gctggagttg ggttgatagc tgtaacgagg attaattttc
     7261 catccttctt atcgctttct ttcagaagat tgtagtcgat ttttgctttg tattttccgt
     7321 actgctccag atatttgtcg tcaatacctg ctttctctgc aatctgagta attggaagca
     7381 tctcgcattc ctgtgcaatt tcaatgtctg atttgaatcc cataatgttt ttctcctttc
     7441 gtctccgcat aacatgaaaa acttctgtta ctgttcattc cgtgatcagc aacaattatt
     7501 aattgaaaga agtatcggcc ggtctgtctg acattcctga tttctgccct gaaagttata
     7561 aaaaaaggcc agtatctgaa tatttcaaat actgcccaga cggtcggctc ccacaaacct
     7621 ccgactacac gtggtttgca ctccactctt tccgtcagta ctcgaaggtt ctttcaattg
     7681 atgagtataa tatatcattt tgagaaaaaa atgtcaagaa aatttttgct gaaacgtcaa
     7741 aaaatgagaa taaactggat aaaagttgtg caaattgata ggagaaaaga atcgtaatcc
     7801 ctggtaatgg aagaaaatgt gttttctcaa gaagaaaaat tgttaaaaaa taaacacagt
     7861 tttcccggat aaataaagaa aatataaaaa gagggtaaag cctgtgcaaa atatggaaaa
     7921 tggaattgac aacagttcag aaagtatgtt attctcatct ttagtatgaa aagacactat
     7981 cgttttcatg caaatatttg ctcacattca gagacagttt ctgaatgtta agccatacgg
     8041 acaggcgggg cagttgccgg gtgggagaca ccacattatt gattgagtta gaagctcaaa
     8101 ttttataagt tgattacttt ataataatca gtgcgtaagc acacatcatc ttgtgaaacg
     8161 gtcaataaga gcatagcata tatttgccag cgattgaaga cgacagcagt catgaatatt
     8221 tcagaatatg ggaacaggcg caggatacag acggatttat acgggaaatc tgctcagtat
     8281 agagagagac agagcctgag aaattctata gatcatgaga gaagcagatg gtgaatgaac
     8341 ttatctgctt ctttttttgt gcagatatag caaatatata ggcgttggag ataaacgctt
     8401 tgcgaggacg cacatgcgtt cggcctgaat atatagagaa ataattgaat cattgtgccg
     8461 atgttaaatc agtatacaat tgctgaatga ttgaactgta tttgccggta catgacaaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaaggg
     8641 gaagaggaaa tccggagctt gcacagcttc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc acccggtttc ggtgatcaga gaagcggagg
     8761 agctggcagc agatgctttt ggcgcagcgc atgcatttct tatggtagga ggaaccacat
     8821 ctgcagtgca gagcatgatc ctttctgtct gtaaggcagg ggataaaatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg cggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgca cagctgggta tctcccttgg catggaggtc agtcaggtgg
     9001 agaaggctat ggatgagaac ccggatgcgg tggcggttct tgtaaataac cctacctatt
     9061 atggaatctg ttcggatctg cggactatcg taaagaaggc tcatgcaaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtgtccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gcatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agtgcttcct atcttctgtt gtccagtctg gatatatcca
     9361 gaagaaatct ggcactcagg ggagaggaat cctttgaaaa ggttgcaggg atggctcagt
     9421 atgccagaga ggagatcaat gagatcggcg gctattatgc atatggtatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc catttataca ctgggaaatg
     9541 gactggcggg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccattgg agacaggctt caggatattg
     9661 agagactggt aggggcactg gctgatattg aacgtctgta taagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctgggga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtggaaca tcttcaggtt ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtatttt ctgacaaaga tgaatttatt tatgatgaga tggtcacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg atcatcggcg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtagaatc
    10321 cgataaaatg tttgtagatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaatattt attatgaaga cggtcttcgg ttcctgcgga ataaaaaggc
    10441 cggatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gatgatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggcggg gtagcttcgg tagcaattcg caaatgctgt
    10921 cagaacagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaaggtagat
    11041 gcggataatg cagaagaggt cgcagaactg atcagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgca
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctatgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgagaaatt taaggaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgca tatgccctga agcattattt tgatgaaatt
    11401 cataccattg atattctgga ctgtaacggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaatccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct atgatttccc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa gaatattccg
    11641 ggagtacaga ggatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtgggaat gctttctacc gcacctgtgg aatttaatgg acaggagatc
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc agctgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttccg gctttgccct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatagag gaactggatc ggatctgtga
    12421 ccatattatt tttaattcca cagcacagct gaagaaattt aaagaagtgt gtaccagatc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg cgatctatga
    12541 tccctgtgcg ccgggttcca ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatc gacggactgc attttcatac gctctgcgaa cagaatgcgg atgatctgga
    12661 gaaaacattg caggcggtag aggagaagtt tggagaattt ctgtctgagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatgagat
    12901 cagaacgctg attctggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgcctgg caggagatgt gatcggagat tattcctttg acagagagat
    13081 ccggatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaat ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcgcaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaatgtatat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agcttgggaa tgtttcgggt gtgactttgc tggaatgcga gacagatgat gcctgggcga
    13561 gagatgtggg agcaaccatg gttctggatg agaaagaggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggagga gactttgacg gactttaccg gaactgggaa aaggatgaca
    13681 gggtagctgc ctttatctgc aggactcttg gttgtccatg tctggatgcc agaccttttg
    13741 tgctggaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagtaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtctct ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccgg gaagatgtgg atggctttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggctgcca gttatgtgaa tttctatatt tccaatggag
    14221 ggatcatcct tccacaattt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gtcggcggtg
    14341 gaaatattca ctgtattacc cagcagattc ccggaaaaaa tatctgacct tgatgcagaa
    14401 aaactttgag agtcatgtgt ttgcgggtta ttacctgaaa gttatgaaaa aacttactta
    14461 taaacaggag caggaggaac agacaggatg agaaatgtaa cagtggcagc agttcagatg
    14521 aaatgcagta aaagtgtgga gaaaaatatt gcccatgcag aggaactggt gcgtcaggca
    14581 gcagcaaagg gagctgagat tgttcttctt ccggagcttt ttgaacggcc ctatttctgc
    14641 caggagcgca gatatgagaa ttatgaatat gcgcagactg cagaggaaaa ccctgcagtg
    14701 cgtcatttca gcagggtagc ggcagagctg gggattgtga tcccggtcag cttttatgaa
    14761 aaagaggtca ataatactta taacagcgtt gcggttctgg atgcagatgg aaagaatctc
    14821 ggcatttatc ggaaaacaca tattccggat gaccattatt atcaggaaaa attctatttc
    14881 acaccgggag ataccggctt taaggttttt gataccagat ttggaaccat tggagttgga
    14941 atctgctggg atcagtggtt cccggaaacg gcaagatgta tggcactgca gggagcagag
    15001 cttctctttt atcccactgc catcggaagt gaacccatcc tggaatgcga cagcatggaa
    15061 cactggagaa gatgtatgca gggacacgct gcctccaacc tgatccctgt gatcgctgct
    15121 aacagaatcg gtgaggaaac agtagagcca tgtccggaaa acggaatgca gaaatctgct
    15181 cttaattttt acggctcttc ttttatcaca gacaacacag gtgctctctg tgcagaattg
    15241 cccggagggg aagagggggt gcttgtaagc acttttgacc tggatgcatt aaaggcagac
    15301 agactgaact ggggactttt cagagaccgc agaccggaga tgtatgcaaa aattgtcggg
    15361 aaatgacata caagccaaaa ttccattgcc gcaggcaatc tggaatgaat tttggctcag
    15421 ttactgagaa cggagtgaac agtaactgag tttataagaa tttcataaaa agtttatgat
    15481 tatattagtt gctacctgta gtatatatgg taaaataaga gtacgaacgt tactgataac
    15541 ggagcaggaa agttttgaca tgtatttctg gcaaaatgga gtgtaaaaga tgaacagaaa
    15601 agaatttttg gaaatcctga gaagccagct tgccggtcag atgcaggagg gcaaagcagc
    15661 ggcacatatc aggtattatg aagattatat acagtctcag gtacgtggcg gacgttcaga
    15721 gcaggaagta ctgcaggaac tgggagaccc acatctgata gcaaagactc tgattgatac
    15781 agatgatgga agtacacagg aagattacgg agagtattct tcttacggaa gcagttatgg
    15841 caatgagaca gagtttcctc atcagcagga gaaacgatgg aaaaaagtaa ttgatctttc
    15901 tacctggcat ggcagggctg ttgttattgt agcagcggct gttataatta ttttactgat
    15961 actgataatc ggagttgcga ttccgttttt tattattctt gcaattattc tttattttct
    16021 ttcatggctg aagaaaagaa ataatcaatg aaaatctatg cagggtttca gaaaagaaac
    16081 cctgcgcaaa atcttaaaaa ttttaaaaat ctaaaaaatc ttaagtgtaa acattcttgt
    16141 ttcacgatat taattcccct tgaatattta taatcataca atttcaactt atttctattc
    16201 tttaatcctg cctggtgcag ggaaaaatcc cacattcatt tttatatttt ttgttcggaa
    16261 aggagacgga aaatgaaaca caatttcaaa ctgaaagaac gccttggagc tttgctgctt
    16321 gcaatgcttt ttattctgca ggcaattctg gggcttgtgc ctgtctgcgt aactcaggcg
    16381 gcaccgttaa ctgtagaaac atgggatagt gacaaggtgg tagattatgg ttatcgcttt
    16441 aacatgaagt ttcagcccgg aattaccaca tatgaatctt ttgggtgtga taatctggac
    16501 agggaagctt tttcagacaa tggaaaaagt gaacgtgaca cagagtgcgt tcgtgtagga
    16561 gcggactata aagccggaag cgcagggatg cgttataaca atgtaggaaa agatggaaat
    16621 ggaaatattg ttgatgtcag actcattctt gtgggagtag agaatgcaga accccgttat
    16681 gatctgcgca ctgcagaatc gattgttcag aataaaggcg gagctacgtt tgcatggaaa
    16741 gataatgaag cttatccaat ggttggcttt tccaaaaaca gtatcggtgt atttatttat
    16801 tctgtaggat acgcaaaggt taagtttcag tttctgaagc atggaacaga agaaacactg
    16861 ccgatcagtg gacatggaac catacgtgat attgatgcgg gacagggagt ccgtattccg
    16921 tcagacagca gtctggataa tgcatatgtt ctgaaaaaca atgattatct gacggtagat
    16981 gggaattctg taagctcacc ccttggttcc gttgagccgg atgatccgag aggatggttg
    17041 aatctttttt ataatacaga taattttacg gtagaattct gtcatcagtt cagactggat
    17101 aaatgggata aaagtcgtga agatgccatt gcaaaagccg gttctcagga aagatgggca
    17161 gagattacaa gaaataaata tctggatcca tcaggcaaca gttattgtcc gaactttaaa
    17221 ggacagaaat actgcaaagc atatgcatat tttgatttta catcctattg tttcggtgat
    17281 gttgagatga aaaaagcgcc cgagaaacgt gtgggagagg caaactgtac atgggaacag
    17341 gcagctgccg catcaaaaga aaaacctttt ggcattcgtc agggacagga atttcagtat
    17401 atgatccagg cggaggtgac acctaataga ctgaaatcct ttgtggtaca ggatatactt
    17461 gaggattgtc ttactataga ggatgcatca aaagtcagta tcgtgaatga tgcagggcag
    17521 acagtgacag actggtttga tgttgctgtt gaaggacaga aagtgacctg cagcgccaaa
    17581 gcagagagta ttcaggatga agcatttaca gataatcaga cttacacatt tactttaaaa
    17641 gtacgccaga gaccggaatc agaaatcaac atttcaaaat accttgcaga ggatggatac
    17701 agtattcttg taccgaatca cgcatccatg agttatgaac gtacaaacgg aagcggcgat
    17761 acaatggata cggaaacagt gtgggtaaag agtgtgattc caccggaact ggaagtaaag
    17821 aaaaatactt ctcagtatga atggaaaacg ggagatatca tagattatga ggttctggtt
    17881 tctcagacaa aacaggatgt aaaagcagta aatgttgtta ttacagatga gattccatca
    17941 tgtctgcagc ttctggaagg gcagtatact gtagagacaa gtcagggagg tgagaactgt
    18001 acgcttaccg gacagggaga aaatggatgg aaagcagagt gtccgtccct gaagtatggg
    18061 gagacgatca caatccgttt taaatgtcag gcatctgcgg attccaatgg acaggaatgg
    18121 gaaaatattg tgactgcaac agcggataat ctgatcaatc ctgagacagg agaacaggaa
    18181 tccagaaagg atatggcaga agtatggccg aacagtccac agcttgaaat tgataaaaca
    18241 gcagacaaat atgaatggca ggcaggagag caggtagctt accggatcgt ggtgaataat
    18301 gtaacggcag gaacaattgc aaaagatgta actattactg atattggttt gccgcaggga
    18361 ctggttctgg caggtggtgc acagagcatg gaagtactgg gagttcagca acaggtaaac
    18421 tatcccgtac cggataagaa aacaggacag gcatatgaag cgagacctgt ggattctcag
    18481 ttgaatgcag atgagaacgg attttccttt tattgttctt atgtgccata cagtcagcct
    18541 gtaacgatta ttttccattg tatcgcacag gaagaggcaa atggacacga aagcgtaaat
    18601 gcagcaactg taaaagctgc taatacagat gagagatctg atgacgcaga agtatatgta
    18661 aattcaggag aattctggat tgagaaatct gcagatcatt atgaatggca ggtcggagaa
    18721 caggtacagt acaatgtggt ggtggagaat aaaaaagcag gtacagtggc ccggaacgta
    18781 actgtctggg ataccggtat gccggcagga cttgcgcttt catcggcaga ggatgtatcg
    18841 gtaagcggaa tcccacagag tattacgcag ctgacagcag ggaccaaaga tgttttgaac
    18901 cagctcaatc cggaatttta taatgagaca tcagagaaac cggtgaatta tgaatttctt
    18961 caggagggaa gcggatggag actgaacatt tcagatcttc cggcaaatac tccggttatg
    19021 atttctttcc tttgcacagt tacggaagcg gcaaatggaa tggaaagcat taatgttgcc
    19081 aatgtgcagg cgcagaatgc ccctgtttca caggatgacg cagaagtgta tgtaaataca
    19141 gcagttcttt ctattgagaa aagttttcag aatccatatc tggcagccgg ggacggacgt
    19201 gcggaaaatg aatttcgggt aggagaacag gtgaattatc aggttacggt taataatctt
    19261 cagaagggat ctatcgcaag aaatcttgtg atcagtgatc tttcccttcc tgaagggctg
    19321 gctctggacg gagctgaaga tgctgttact gtaagcggtg ttccggctgt tattcagaat
    19381 ccggtggcag gaactgatga tgcaggaaat cagctgaatc cggaaaatta taaagaaaca
    19441 gtggaaaaac cggtcagctg tcaggttaca cgtcagggaa ccggatggat cgtgacgatt
    19501 tcagatcttc cgtatcagac acctgtgact gttaatttcc gctgtactgc gcaggaaagc
    19561 gtaaatggga tggagattgt aaatacagca caggcatatg cagataatgc acagaaagta
    19621 aaggactcct caaaaatctg ggtgaactcg cctgttctta aagtagagaa gacgacggac
    19681 aaaccatttt acaaatatgg tgatattatt acataccgca ttgtcctgac acaggagcag
    19741 accggatgtg tggcgcgtaa tgttactctg caggatgtga tcgatactca gggagtacgt
    19801 cttctgaaag attcggtgat tctgatggat gagaaaggaa atgtggcaga tgctgatgta
    19861 cagatcaatg atgataatac tttcctgatg tcaacaggca ggacactggt cagggatagt
    19921 agatatagta tctgcgataa tgataaaggc ggtctttttg agcaggtaat gtataatcct
    19981 ctggactgtc aggaacagaa aagtatgatc gtggaatatc aggcagcagt gattgatgca
    20041 gccctggcag gacagaaagt gcacaatact gcagttgcag acagcagtga aaagatacct
    20101 gcaaccgggg aagcagagac agaggtacac agtccgattc tggaaattgt gaaggaatca
    20161 gataagaaag agtatgcgtc cggtgaaaaa ggatactata aactgacagt aagacaactg
    20221 cgtgaggatg tcacagatca gaatattgtt atcgaagata aactggaaac ccaaggggct
    20281 ttcattgtaa aagacagcat ttttgtgaag aaaaacggta tagaactgaa agatgccaaa
    20341 atagaggcag atgatacagg atttgtaatt cagacaggag catcgttgtc agatatggat
    20401 aaaattgaag tctgctatga aatggtattt aaaacagaaa gcacagagcc tgaaaaaatt
    20461 gtaaacacag cgaaagcaag aggtgatatt tcaccggaaa ttactgcaca gcaggaggca
    20521 tatgtgaaag caaaagcaga acccactgcc acaccaacac cgtctgccac accgaaacca
    20581 acagaaacac caaagccgac agagacacca aaaccaacag aagtaccgaa accaacagag
    20641 cagccaaaag tcacaccaac accatctgta ccgggaacct gcccgaaaat gactcctgta
    20701 ccgacgaaag caccgttagc atcttataat ggtggaaata atggaggcac aacttccgga
    20761 agcggaggca gcagttacgc aaattcgggt ggatattccg gtggatatgg aagctatcag
    20821 ggtggttcca tggcaggaag ttctaaaaca ggagatgtca gaccgtttaa aatgatggct
    20881 gttcttggac ttatcggaat gggactgctg acaggaggtg tggtgatcta cagaagaact
    20941 gtttccggga agagaaatat aaagggtatg ccgcggaaat gaaaaaattc agaacatttg
    21001 cagtaagtat gatcatagca gcaatcgggc ttcttatata ttgtgccggc ttctatataa
    21061 aaagttatga acagaatctt gcagcaaggc aggaatatgc agagctttcc caaatggcag
    21121 gggtgaagaa cagagaaggt gccggattat tggcagatgg caaaaaaact gatgaagaca
    21181 gcagtacaaa aaacagtgaa aaaaaacgca ggaaaaaaca gagaagatct tctgaatcaa
    21241 aaaacaaaaa ctgtacagat gaaatcaggg aatccttcgg gatttcctgg gaaaatttaa
    21301 gaaagatcaa ctctcagaca gttgcctgga ttactgtccc gggagccgat atttcttatc
    21361 ctgtagttca ggcggcagat gatgaatatt acctgaaaca taatttcaga ggagaggaag
    21421 atctgtttgg atgtattttt ctggaacatg acataaaaaa gaattttaca gattcccaca
    21481 gtattcttta cgggcataat atagaaggta atatgatgtt cgcaaatctg aaccgttatg
    21541 aacagcctga atttctgaaa aaatgtcctg aaattgagat cacaacaccc aaaagaaagt
    21601 ttctgtacaa aattttttct gtggaacagg catcttccca aagcccggca tttgaatatg
    21661 gatacaagtt atccagtcct gcatacagga gacaattatc tatattgaaa aataattcca
    21721 tgtatgacac aggagtagag cctgatgaaa gggagagaat ggtgactctg atcacctgta
    21781 attcacgtct ggataaagaa atacgtatgg cggtacatgg gatttgccat gaatgttatg
    21841 gtatagaaaa agctgagccg aagtgatgtt gaaatcaatc ggatattggt aactttcgta
    21901 aaggatgaac tgttactgtt tatacatcac tatccctcga ggtgttttgg aaaaaactaa
    21961 tgaaaaatct ctcgatattt tgtataattt atgcataaaa aacaacttgt tcgtacgtgc
    22021 gtacaagttg tatcctaaat acaggaggga agaagacatg acagataatg gaaagccgaa
    22081 atatttctca ctaatggaac agcttagaag tgatattgtg tcaggagcta tccggccggg
    22141 agagaagctt ccttcagaaa atgagctttc acagaaatat tccctgagca gacatacggt
    22201 tcgtaaggca ctgggaatcc tggagcagga cggatatgtg gaggcatttc acgggagagg
    22261 tacctattgc tctgagaatg tgcgccatat aaagaattca aagaatattg cggtagtgac
    22321 cacatatatt tctgattata tttttccgag actgatacag ggaatggata atgtcctttc
    22381 agtaagcggt tacagtatta tcctgaaaaa cacagcaaac agcagacaga aagaggccag
    22441 atgtctggag gaacttctga agaaagatat tgatggactg atcattgaac caagcaaaag
    22501 tgagatgatc tgtaaacaca gaaatcttta tcagaatctg gataaatttg gaattccgta
    22561 tgtgtttatt cagggaatct attcagaaat gagggataaa cctcatattc ttatggatga
    22621 tgcacaggga ggctatcttg taacaaaata tctgctggaa ctgggacata aaaagatcaa
    22681 gggtttcttt aaggcagacg atatgcaggg actggagcgc cacaagggat atgtgaaggc
    22741 cttacaggag tcagggattg tctatgatcc tgatgatgtt gtctggtttc atacagagga
    22801 caggaaagta aaacctgcac tgatggcaaa agaaatggta cagagcggac agcttccgga
    22861 tggaatcgtc tgttacaatg atcagattgc tgttcaggtt atggaagaac tggagaaaat
    22921 gggagtcagg ataccggatg atatttccat taccggttat gacaattcac tgtatgctca
    22981 gcgaggaagc ggaatcacaa cgatagctca tccgcaggaa aagttgggag aaatggcagc
    23041 agagcttata cttgagaaga tcaacggagt tcctgaagaa gaaagtaagg ttgaaagact
    23101 gatttatccg gaactgatca tacggggatc atgcagaaaa atattgtaaa caaatgaaat
    23161 aaataaaaaa taaaaataaa tccaggagga attttatcat gaaaacagga agaaactata
    23221 agttttggtt ttgtacaggt tcacaggat
//
