LOCUS       gnlProkkaDIGMNBLD_69    5869 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DIGMNBLD_69.
ACCESSION   gnlProkkaDIGMNBLD_69
VERSION     gnlProkkaDIGMNBLD_69
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 01:48:53
            Original ID  :: gnl|Prokka|DIGMNBLD_69
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5869
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5869
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1657:5869]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1658..5869
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..5869
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5869
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..593
                     /locus_tag="ctg69_1"
                     /transl_table=11
                     /translation="MTNYPSAELFINGKSQGKRTKDLSVTIDNSADSVSIMNLKRQSRY
                     RLMWMDTKYEPGTVKVVAYDADGKAVAEKELHTAGKPDHIELVADRNVIKADGKDLSFV
                     TVRVVDKDGNLCPDASHEISFKVKGEGSYRAGANGNAASLESFQRPKMKVFSGMMTAIV
                     SSTEQPGKITLEATGKGLKKGTLIIESRQEAKK"
     CDS             927..1481
                     /locus_tag="ctg69_2"
                     /transl_table=11
                     /translation="MNDLDKERQTEGRKAWYAVQTFYCKEEHLGKYLEKKGVNYFIPMR
                     YIEHETLDGKKHRKLTPAVHNLLFIEKEFTEKELLERVKDCTIPFLLVRDRSTRRCYEI
                     PDCEMLEFRAVCDPNYKGTLYVDTVTAEARPGQAVRVIRGPFAGLEGKLTQYKKSYYVV
                     VTLATIGVMLHIPKWYCEKIN"
     CDS             1658..2551
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 268.8; E-value:
                     9.3e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 8e-14, bitscore:
                     41.0, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAG
                     IREILIISTPYDLPGFKRLLGDGSDYGVRFEYAEQPSPDGLAQAFIIGEEFIGNDSVCL
                     VLGDNIFYGQGFTRMLQEAVYTAEEENKATVFGYWVADPERYGVAEFDKMGSVLSIEEK
                     PIQPKSNYAVVGLYFYPNKVVEIAQNIKPSPRGELEITTVNQQFLLDQELKVKLLGRGF
                     AWLDTGTHDSLSEASTFIEVIEKRQGLKVACLEGIAFRQGWISSEKMKVLAQPMLKSQY
                     GQYMLKMIDITTSNEE"
     CDS             2724..4028
                     /locus_tag="ctg69_4"
                     /transl_table=11
                     /translation="MIYMFTRMIRSLLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTA
                     AIYEGEILWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVAL
                     LGFALLPVPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKT
                     LGQFVMDNLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKD
                     RRKFLRQFFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFV
                     LVLMFLIVFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMG
                     YIPFTYLIERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRT
                     ALFSGFVSVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             4042..4740
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_5"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.6e-15, bitscore:
                     44.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKALLSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKDALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             4760..5869
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 170.6;
                     E-value: 6.8e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_6"
                     /sec_met_domain="CTP_transf_like (E-value: 1e-13, bitscore:
                     40.4, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-100, bitscore:
                     325.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 7.9e-54, bitscore:
                     171.3, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVCEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYD"
ORIGIN
        1 tgtataccaa ctatccttca gccgaattat tcatcaacgg aaagagccag gggaaacgta
       61 ccaaagacct ttccgtaacc attgataata gtgctgactc tgtttccatc atgaacttga
      121 aacgtcagag ccgttaccgc ctgatgtgga tggatacaaa atatgagcca ggcacggtga
      181 aagtcgtggc ttatgatgct gacgggaaag ctgtagctga aaaagaactc catacagccg
      241 gtaaaccgga tcatattgaa ttggtagccg atcgtaatgt aatcaaagcg gatggaaaag
      301 atctttcttt tgtaacagtg cgagtggtag acaaagacgg taatctgtgt ccggatgcct
      361 cacatgaaat cagtttcaaa gtgaaggggg agggtagtta ccgtgcagga gctaatggta
      421 atgcagcttc cttggaatct ttccagcgtc cgaagatgaa agtcttcagt ggtatgatga
      481 ctgctattgt atcttcgaca gagcaaccgg gcaaaataac ccttgaagct acgggcaaag
      541 gcttgaaaaa aggaaccttg atcattgaaa gccgtcagga agctaagaag taagaaatat
      601 cgttgtaata tatgtaattc ctctaagtgt ttcattgcga cacacttaga gggatttttg
      661 tttaagcaga caggagttta acatctttgc aggcaaaata aaagctgtaa aagtatgttc
      721 ttttattaaa ttgtattact tttgcatcgt tttagtactg tatccgtttc tctatgaacc
      781 ttggttctta tatggagata agataaaaag gctaaatcct taagagatgc gctactgctt
      841 cataaatgga tttcatttgt gaaagtcagg gcgcttttgt cttttaagta agtgatgaaa
      901 taaaaaacaa ggggtaatgg gtgataatga atgatttgga caaagaacga caaacagagg
      961 gaaggaaggc atggtatgct gtacaaacct tctattgtaa agaagaacat ttggggaaat
     1021 atttggaaaa aaaaggggta aattatttta ttccgatgcg atatatcgag catgagacgc
     1081 ttgatggtaa aaagcatcgg aaactgactc cagctgtaca caatctgctg tttatcgaga
     1141 aagaatttac ggaaaaagaa cttttagaaa gggtaaaaga ttgtactata ccttttttgc
     1201 ttgttcgtga ccggagtaca cggcggtgtt atgagattcc agactgtgag atgttggaat
     1261 tccgtgccgt atgcgatcct aattataaag gaactcttta tgtcgataca gtaacagcag
     1321 aagcccgtcc cggacaagca gttcgggtga tccgtggccc gtttgccgga cttgaaggca
     1381 aactcacgca atacaagaag agctattacg tagttgttac gttagctact atcggcgtca
     1441 tgctacatat tcccaagtgg tattgcgaaa aaatcaacta atcataacat tacgatcatc
     1501 tgctcaacac cttgttgtcg gacacttcat gtctgacctt tagaactatt tttttttaat
     1561 ctcggaaggt aatctatttt tttaataaaa tattcaattt tttgagtgga aggatatata
     1621 ccctgccact caaatcttga gtactaataa caaatcaatg aaaggaattg ttttagccgg
     1681 tggttcaggt actcgtttgt atccgatcac aaaaggagtg agcaaacaac tgctccctat
     1741 ctttgataag ccaatgattt attatcctat ttcggtattg atgttggctg gtatacgtga
     1801 gattctgata atttctactc cttatgatct tccgggcttt aaacgtcttt taggagatgg
     1861 ctctgattat ggtgtacgtt ttgaatatgc agagcaacct tctccggatg gattggctca
     1921 agcatttatt atcggagaag aatttatcgg taacgattct gtttgtctgg tactaggtga
     1981 taatattttc tatggtcagg gtttcacccg tatgctgcaa gaagctgtgt atactgcaga
     2041 agaagagaat aaagctactg tttttggata ctgggttgcc gatcctgaac gttatggtgt
     2101 tgctgaattt gataaaatgg ggagtgttct gagtatagaa gaaaaaccta ttcagccaaa
     2161 atctaattat gcagtagtcg gtctttattt ctatcctaat aaagtggtgg agatagccca
     2221 aaatatcaaa ccttctcctc gtggagaatt agaaataact actgttaatc aacagttttt
     2281 gttagaccag gaactgaagg tcaaattatt agggcgtggc tttgcttggt tggatacagg
     2341 tacgcatgac tcgctgtccg aagcgagcac ttttatcgaa gtgatagaaa aacgtcaagg
     2401 gctgaaagtt gcttgtttag agggaattgc ttttaggcaa ggttggattt cttccgagaa
     2461 gatgaaagta ttggcacaac cgatgttaaa gagccaatat gggcaatata tgttgaagat
     2521 gattgatata acgacctcta atgaggaata gatgcctgaa ttagatagta aaaaaattaa
     2581 taatactgac ttcttcaaat atagctaatc cttataattc tttatttatg gataaataga
     2641 tttctgagtg ttttttattt agcgaataga atatttttac attcagccct gttaaatcgt
     2701 aatttgaatt gtcgttacat tggatgattt atatgtttac acgaatgatt cgttcccttc
     2761 tttcccgttc tcccctttac gttttggctc tctatgccag cgttttgatt tttctggttt
     2821 atacctgtgc ctatgcctac cgtaagccat ttaccgcagc catttatgaa ggtgagattc
     2881 tttggggatt cgatgtcaaa atcctgtatg tcctttctga gattatcggc tacgcccttt
     2941 ccaagttcat cggtgttcgt attctgcctt cgatgaaagc gggtcaccgc atctattata
     3001 taatagggct gcttactttt tccgaagttg ctttgttggg ttttgcactt cttccggttc
     3061 ctttgaaggt gtgttctatt tttctgagcg gtcttcccct gggtatgatc tggggtgtca
     3121 tttttagcta tatcgaaggg cgtcgtatca gtgaaatatt gaatgtcggg ctgagcgttg
     3181 ctttgatagt ctcttccggt ttggtgaaaa ccttgggaca attcgtgatg gataatttgc
     3241 atgtgtcgga atattggatg ccttttacca ccggtttgtt ggtataccct gttatgttgc
     3301 tttgcagctg gcttctcaat cagattccgg ctcccaatga gcaagatatc atacagcgta
     3361 ccaaacgtgc tccgatggat ggtaaagaca ggcgtaagtt tttgaggcaa ttcttttggg
     3421 gaatctgcat gctggttgtt ttttacggtg ccctgaccgt gttccgtgag cttcgtgact
     3481 ctttcgctgc cgatatttgg aaggagctcc atattgaggg tgcaatgatc tttactcaga
     3541 cagaggttcc cattgccgtt tttgtccttg tactgatgtt cctgattgtg tttgtccgta
     3601 ataaccgttt ggctcttaat atcatttatt gcatcgccgt cacaggcggt tccttaatgg
     3661 ttttttccac attgctttat gtgtacggtt ttctttctcc tatttggtgg atgattcttt
     3721 ccggtcttgg tctgtatatg gggtatattc ctttcactta cctgatagaa cgtctgattg
     3781 cttcccttag ggtggttagt acggctgttt ttattattta tttggccgat tctttcggct
     3841 atctgggcac tacgggtgtg tttatggtca agaacttcgt ttctgctgac atttcctgga
     3901 ctgtcatgct gatgcgtact gccctttttt caggatttgt ttctgtcctg tcgatttttg
     3961 cgatttactg ttatttcaag caacaattga attcacttat attaattccc tctgaaattc
     4021 atgattaaaa cagcaatgat catggctgcc ggtcttggta cccgcttcgg gcattatacc
     4081 gagcttgtgc ccaaaggttt tgtggaggtt ggtggaaaac ctatgattat ccgctctatc
     4141 gaaacccttc tttcctgcgg tatcgaacgt atcatcctcg gtacgggtta taaaaaagag
     4201 gcttatgaag cccttcaggc ggatttcccc cagatagaga cctgtttcag tccccgttat
     4261 gccgatacta acagtatgta cactctgtac aatacgcgtg acgtgatagg cgatgacagt
     4321 ttcctgctgc ttgaatcgga ccttgttttt gaacgcaagg ccctcctctc gctgctggat
     4381 gacgaattcc cggatgtgat gcttgtctct tctctgacca agttccagga tcagtattat
     4441 gtggaatatg accgcaatca catccttact tcctgttcgg tagacaagga cgcccttgag
     4501 gcaaaaggcg agctggtcgg tatccataaa ctttccaata ctttctaccg ccggatgtgc
     4561 gccgattatg cgaccatcct ggagtcccag cctaaactgg gttacgagta cgaactgctc
     4621 cgcatgtccc gttccgtttc ccctgtccgt gtgctcaggg tggagggtct taaatggtat
     4681 gaaatcgatg atgaagccga cctttcgtat gctgaggagc acatcatccg ctattgttaa
     4741 aaacaaatct tttccatata tgaacaagaa aatctatgtc ggtatgaccg cggatatcat
     4801 gcatccgggg ttgatccata ttattcatga agctactaaa tacggtgatg tcatcgtcgg
     4861 tctgctgacg gacaaggcca tcgccgaaca caaacgcctc ccttacctta cctatgatca
     4921 gcgtaaggag gttgttgaga atatcaaagg ggtttgcgaa gttgttcccc aggaggattg
     4981 gagctatgtt ccgaatctgg aaaaactcaa gcctgactat atcatccacg gcgacgactg
     5041 gaaaacgggc ccgttgcgcg aggtgcgcga acaggttttt gaggtgatga acgcccaggg
     5101 gggcaaggta atcgagatcc cttatacccg gggcatcaac tcctcctcgc tcgacaagga
     5161 tatcaaggcg atcgggacta cccctgacgt acgtcttaag tccctccgcc gcctgatcca
     5221 ggccaagcct gtggtccgta tcctggaggc tcacgacggt ctttgcggtc tgattattga
     5281 gaatcttgaa gtccagaagg gtgataagcg cgaggtcttt gacggcatgt ggtccagcag
     5341 cctgaccgac tccacgagta agggtaaacc ggatattgaa gcggtcgacc ttaccacccg
     5401 tttacaggac ctgaacaata tccttgaatg taccaccaag cctattattt ttgatggaga
     5461 cacgggtggc aagatcgaac actttgtctt tactgtgcgc actctggaac gtcacggcat
     5521 ttctgcggta atcattgaag ataaagtcgg tctgaagaag aattctcttt ttggtactga
     5581 cgctatccag actcaggata gtatcgaggg tttctgcgat aagatcagag cagggaagaa
     5641 tgcccaggtc accggtgact ttatgatcat tgcgcgtatc gaaagcctta ttgccggcaa
     5701 acccatgagt gacgccctcg aacgtgctta tgcctatgta caggcgggtg cggacggcat
     5761 catgatccac agcaaggata agtcgggtga ggatatccgt gagttctgcc ggactttccg
     5821 caaagaatac gcccatgttc ccattgtcgt tgttccgacg acttatgac
//
