LOCUS       c00013_gnlPro..        14272 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DIGMNBLD_13.
ACCESSION   c00013_gnlPro..
VERSION     c00013_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:19:21
            Original ID  :: gnl|Prokka|DIGMNBLD_13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14272
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14272
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[28:4272]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      29..4272
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14272
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14272
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             29..1366
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_1"
                     /sec_met_domain="Fer4_10 (E-value: 6.2e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4.4e-16, bitscore: 50.6,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.3e-50, bitscore:
                     163.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 8.1e-30, bitscore: 94.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.3e-05, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PIVAKGDMVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTVVDASGYAKPAIFIDVEGDE
                     WEETIDRSKTLVKECELSSEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEVMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVTKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             1373..2365
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_2"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 2.6e-120,
                     bitscore: 393.2, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIVKFLMKKPATTICDGSAVITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPVVGQLTSYMDATTGATPL
                     ALMKQAIHGDASALSQIPDALTLFIGQNGGCIGEVSALALLLGLVYMLWKKIITWHIPV
                     SIIVTVFVFAGIMHMVDPEKYVSPILQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             2392..3075
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_3"
                     /sec_met_domain="FMN_bind (E-value: 4.4e-23, bitscore:
                     73.8, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAVSVALLAYVNELTTGPIAEANAKTLNEALKKVLPE
                     YTNNPVAESDTVFSEKDGKKIVDFIIYPAKNGEKWVGSAVEAKSMGFGGELKVLVGFDA
                     EGKIYNYSLLAHAETPGLGSKADKWFGAYDPAKNEKPVSHEESAKSILGMNPGETPLAV
                     TKDMNGQVDAITASTITSRAFLNAVNAAYQAYKGGEVDTNSGASQKNEPAVAPEGEAAA
                     NDTNN"
     CDS             3093..3677
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_4"
                     /sec_met_domain="Rnf-Nqr (E-value: 7e-71, bitscore: 229.8,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPIFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISSIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPDLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNPLASMFDGIGMGFGFTIALTLLGAVREFLGTGKIFNLTILP
                     EEYGMLIFVLAPGAFIALGYLIAIINSLKKA"
     CDS             3700..4272
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.2e-62, bitscore:
                     203.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDAFGLGYLQTITFILVIAGLVQMVEIILKKVSPSLYQALGV
                     FLPLITTNCCILGVAILVIQKDFDLLTGVVYAFSTALGFGLALVLFAGLREQMTLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             4531..5565
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_6"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 2.3e-52, bitscore:
                     170.4, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPAFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVEKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTIASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAMGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEQKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDYANQELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(5798..6622)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_7"
                     /sec_met_domain="GHMP_kinases_C (E-value: 6.7e-10,
                     bitscore: 31.3, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 7.8e-10,
                     bitscore: 31.0, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITFPNAKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     EADKKFSLHQYGMEISGNPEDNLVVKAYLLLDKEFHLCPIEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNEHFQLNLSEDQLEIYAATLGADCAFFIRNAPTFAEGIGNIFSPIPLSLK
                     GYQILIIKPDVFVSTREAFANIHPHHPEYSIKEAIKRPVNEWKEILINDFEDSVFPQHP
                     VIGEIKAELYKQGAVYASMSGSGSSVYGLFEPEGTLPETDWGTNVFCFKGRL"
     CDS             6821..8374
                     /locus_tag="ctg13_8"
                     /transl_table=11
                     /translation="MAEQRRNSRNTKSTKVQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYEHRHQLIYAAITDLAVNQKPVDILTVKEQLSKRGELEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLITNVCEIPSEKIKS
                     GQLASYEWQQLDYKLKDLLDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIYQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKLNAGAMPPPPPEPDFVPQGNNPFGATEGPLPF
                     "
     CDS             8697..11159
                     /locus_tag="ctg13_9"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCEEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPAEAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLDIEVVVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTLPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNGVIYCLKLAALMVKELAGG
                     TISSEIKDVCVAAPQDFMVELSYEKVNSLIGKVIPVETIKSIVTSLEMKIMNETVDGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLVAEQL
                     VGCGFNEILNNSLTRAAYYDGLENYPSNHLVMLLNPLSADLNCMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYYFDADKKNPEKVLATYSEDYHLGLWVTGKKVANSWAHPDENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDIFATALSVHTKGGKRLASFGVVTKKLLK
                     AFDIDNEVYYADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNVQFAEIEKIA
                     YDTEKKLLKEVELFDVYEGKNIEAGKKSYAVSFLLQDETQTLNDKMIDKIMSKLVKNLE
                     DKLNAKLR"
     CDS             11195..11938
                     /locus_tag="ctg13_10"
                     /transl_table=11
                     /translation="MGRAFEYRKAAKLKRWGHMAKTFTRLGKQIAIAVKAGGPEPENNP
                     TLRSVIATCKRENMPKDNIERAIKNAMGKDQSDYKSMTYEGYGPHGIAVFVDTLTDNTT
                     RTVADVRSVFNKFGGNLGTMGSLAFLFDHKCMFTFKIKDGMDMEELILDLIDYDVEDEY
                     EQDDEEGTITIYGDPKSYAAIQKHLEECGFEDVGGDFTYIPNDLKEVTPEQRETLDKMI
                     ERLEEFDDVQTVYTNMKPEEGGNEE"
     CDS             11946..12191
                     /locus_tag="ctg13_11"
                     /transl_table=11
                     /translation="MEYVYRTQGTCSTNIELNVEDGVVKEVAFWGGCNGNLQGLSRLVK
                     GMKVEEVIKKLEGVRCSGRPTSCPDQLCHALHEMGY"
     CDS             12353..13609
                     /locus_tag="ctg13_12"
                     /transl_table=11
                     /translation="MMKNIFQDLKRKDHKRYLGGLDVFKYIGPGLLVTVGFIDPGNWAS
                     NFAAGSEFGYSLLWVVTLSTIMLIVLQHNVAHLGIVTGLCLSEAATKYTPKWVSRPILG
                     TAVLASISTSLAEILGGAIALEMLFDMPIMWGAVLTTLFVSIMLFTNSYKKIERSIIAF
                     VSVIGLSFIYELFLVEIDWPAATMGWVTPAFPKGSMLIIMSVLGAVVMPHNLFLHSEVI
                     QSHEYNKKDDASIKKVLKYELFDTLFSMIVGWAINSAMILLAAATFFKSGIQVEELQQA
                     KSLLEPLLGSNAAIVFALALLMAGISSTITSGMAAGSIFAGIFGESYHIKDSHSQVGVI
                     LSLGIALLLIFFIGDPFKGLLISQMILSIQLPFTVFLQVGLTSSRKVMGNYVNSRWSTF
                     VLYAIAVIVSVLNIMLLFS"
ORIGIN
        1 ataataacag aataaaatac agaattgtat gttaaagaca ttttcaattg gtggagttca
       61 tccacacgaa aataaattgt cggcacatca acctatcatc acagcggaag ttcctgcaaa
      121 ggcagttatt ctgttggggc agcacattgg cgcacctgcc aaaccgatag tagcaaaagg
      181 tgatatggtg aaggtaggca cgaagattgc cgaacctgcc ggcttcgttt cggcagcaat
      241 tcactcttct gtcagtggaa aagtggcgaa gattgataca gtagtcgatg cgagcggtta
      301 tgcaaaacct gctatcttta ttgatgtaga aggcgacgaa tgggaagaaa ccattgaccg
      361 tagtaagaca ctggtcaaag aatgtgagct ttcgtccgaa gaaatcgtga agaagattgc
      421 cgatgccggt atcgtaggtt tgggtggtgc ttgttttcct acacaggtga aactttgtcc
      481 gcctccttcg ttcaaggcag aatgtgtgat tatcaatgcg gtggaatgtg aaccgtatct
      541 gactgccgac catcagctga tgctggaaca cgcggaagaa gtcatggtag gtgtctccat
      601 tctgatgaaa gccgtgaagg taaataaggc atttatcgga attgagaata acaagccgga
      661 tgctattgaa ctgatgacga aagttgcttc cagttatgca ggcatcgaag ttgttccttt
      721 gaaagtgaaa tatcctcagg gtggtgagaa acagttgatt gatgcgatta ccaaacgcca
      781 ggtggcaagt ggtgcgctgc ctatctctac tggggcagtt gtgcagaatg tgggtacggc
      841 atttgctgtt tatgaagctg ttcagaaaaa taaaccgttg tttgagcgtg tgattaccgt
      901 aactggtaag tctgtgacca aaccttccaa cttcctggct cgtatcggta caccgatgaa
      961 acagctgatt gatgcttgtg gcggtctgcc ggaggatacg ggaaaagtga tcggtggcgg
     1021 tccgatgatg ggtaaggctc tggtgaatat cgaagttcct accgcaaaag gcagttccgg
     1081 catcttgatt atgaatcaga aggaagccaa acgtggtgaa gcacaaacct gtatccgttg
     1141 cgcaaagtgt gtgagcgctt gtccgatggg actggagccg tacttgctcg gagctttgtc
     1201 cgaaaacgga gattttgaaa caatggaaaa agaaagaatc atggattgta tcgagtgcgg
     1261 ttcctgtcag ttcacttgtc ctgccaaccg tccgctgctt gattactgcc gcttgggtaa
     1321 gggtaaagta ggagctatga ttcgtgcacg tcaagctaaa aaataacgaa gtatggaaaa
     1381 taaattaatc gtatcactat caccccacgt gcatggcgga gacagcgtac agaaaaatat
     1441 gtatggtgtg ctgatcgcac tgattccggc ttttctggtg tcgctttatt tcttcggcct
     1501 gggggctctg attgtcacgg ctacttcggt agcagcctgt ttattcttcg aatgggcgat
     1561 cgttaaattc ttaatgaaga aacctgctac aaccatttgt gacggttctg ctgtcattac
     1621 aggtgtgttg ctggcattca atctaccttc caatctgcct atctggatta tcattctggg
     1681 tgcactgttc gcaatcggtg taggcaagat gtctttcggt ggtctgggct gcaacccatt
     1741 caacccggca ttggcgggac gtgtattcct gttgctttct ttcccggtgc agatgacaac
     1801 atggccggta gtaggtcagc tgacatctta tatggacgct accaccggtg ctactccgct
     1861 ggcattgatg aaacaggcta ttcacggcga tgcaagtgct ttgagccaga tacctgatgc
     1921 gctgactctg tttatcggac agaacggcgg atgtatcggt gaagtaagtg cgctggcact
     1981 gttgctcgga ctggtataca tgctctggaa aaagatcatc acctggcata ttccggtttc
     2041 tatcattgtg actgtatttg tatttgcagg cattatgcac atggtggatc ccgaaaagta
     2101 tgtttctccg atattgcaac tactctccgg aggtctgatg ctgggagctg tctttatggc
     2161 aaccgactat gtgacttctc cgatgagcaa gaaaggtatg ctgatttacg gtgtttgtat
     2221 cggtctgctg acggtggtta tccgtctgtt cggtgcatat cccgaaggta tgtcattcgc
     2281 catcctgatt atgaatgcgt tcactccgct gattaacacc tattgtaaac ctaaacgctt
     2341 tggggaggta gcgaagaaga aatgaaaaag ttacaatcat ctttaaagaa tatgttgctg
     2401 gtacttacgg gcgttacagc cgtttccgta gcgttactgg cttatgtgaa cgaactgacg
     2461 acaggcccta ttgccgaagc gaatgcaaag acgctgaacg aggctttgaa aaaggtgctt
     2521 cctgaatata ccaataatcc ggtagccgaa agcgatactg ttttcagcga gaaagacgga
     2581 aagaaaatcg tggatttcat tatctatccg gccaagaatg gcgaaaagtg ggtaggttct
     2641 gccgttgaag ccaagtcaat gggatttggc ggtgaactga aagtgctggt gggctttgat
     2701 gctgaaggca agatttataa ctactcttta ttggcgcacg ctgaaactcc gggattgggt
     2761 tcgaaagcgg acaaatggtt tggagcttat gatcctgcaa agaacgaaaa accggtatct
     2821 cacgaagaaa gtgcaaagtc tattttgggc atgaatccgg gagagactcc attggctgtg
     2881 accaaagaca tgaatggaca ggtagatgct atcacggctt ctactatcac ttcacgtgct
     2941 ttcctgaatg cggtgaatgc tgcttatcag gcatataaag gcggtgaggt ggatacgaat
     3001 tccggagctt cccagaaaaa tgaaccggct gttgcaccgg aaggtgaagc agctgctaat
     3061 gacactaata actaagaaag gaggagacag ttatgaataa ttttaaagta atgatgaacg
     3121 ggattatcaa agagaatcct atttttgtgc tcctgctcgg tatgtgtcct acactgggta
     3181 cgacatcatc ggcaatcaac ggtatgggta tgggactggc cactatgttc gtcctgattt
     3241 gctcgaacgt ggtaatttca tctatcaaga atctgattcc ggatatggta cgcatccctt
     3301 catttatcgt ggtgatcgcg tcattcgtga cactgttgca gatgataatg caagcatacg
     3361 tgcccgatct gtatgctact ctcggtcttt tcattccgct gatcgtagta aattgtatcg
     3421 tattgggacg tgcggaagct ttcgcagcga agaacaatcc gctggcttct atgtttgatg
     3481 gtatcggtat gggatttggt tttaccattg ccctgactct gttgggtgcc gtacgtgaat
     3541 tcctcggaac aggtaagata tttaatctga ccattctgcc ggaagaatac ggaatgctga
     3601 tctttgttct ggctccgggt gcctttatcg ctttaggtta tctgattgcc attattaata
     3661 gtctgaagaa agcctaactc tattaaataa gaaaagaata tggaatatat attgatattt
     3721 atctcggcaa tctttgtaaa caacattgtg ttgtcgcagt tcctgggaat ctgtccgttc
     3781 ctgggtgttt ccaagaaggt ggaaacagcg atgggtatga gtgcggcagt tgctttcgtg
     3841 ctgactatcg ctaccatcgt cacattcctg attcagaagt ttgtgttgga cgctttcgga
     3901 ttggggtact tacagacaat cacttttatt ctggttattg ccggactggt gcagatggta
     3961 gaaattattc tgaagaaagt ttctccttct ttgtatcagg cactgggggt gttcctgccg
     4021 ttgattacaa cgaactgctg tattctcggt gtggcaatcc tggtaatcca gaaagacttt
     4081 gatctgctga caggtgttgt atacgcattc tctactgctc ttggctttgg tctggcactg
     4141 gtattgtttg ccggattgcg tgagcagatg accctggtga agattccgaa aggaatgcag
     4201 gggactccga ttgctttgat taccgcaggt ttgctggcaa tggcattcat gggcttctct
     4261 ggcgtcgtgt aaaagactaa gttgataatt agataaagag gctggaaact ctgtcgtatg
     4321 gcaacataca ggcagtttgt ttccggcctt tttctttata tctgttcata ccgaatatgt
     4381 tttttatcat accaaaacgc cctcaaatcg tcccgtaagt atcttcctgt gaataaaatt
     4441 gcgatagttt attgcatttc cattttattt ccatacattt gtacctcaaa caaactgaaa
     4501 accgaaaaac taaccatatt ttaaaattat atgaaagaaa gaattttagt aacgggagga
     4561 acaggctata ttgggtctca taccgttgta gaactacaaa acagtggata cgaagtaatc
     4621 attatcgata atttatcaaa ttcgagtgct gacgttgttg acaatataga gaaagtatcc
     4681 ggtatccgcc cagcttttga gaaactggat tgtcttgatt ttgctggcct tgatgccgta
     4741 tttgccaaat ataaaggaat taaagcgatt attcatttcg cagcaagcaa agcagtagga
     4801 gagtcggtag agaagccgtt gctttattat cgtaacaacc tggtttcttt aatcaacctt
     4861 ctggagttaa tgcctaaaca tggagtagaa ggcatagtgt tctcttcttc ctgtacagta
     4921 tatggtcaac cggatgagtt gcctgtaacg gaaaaggctc cgatcaagaa agcggaatct
     4981 ccttatggaa atacaaaaca gattaatgaa gaaattatcc gtgatacaat agcttccggt
     5041 gccccgatca atgctatttt gttacgttat ttcaatccga ttggcgcaca tcctacagca
     5101 ttgctgggtg aacttccgaa cggtgttcct caaaacctga ttccttatct gactcagaca
     5161 gcgatgggta tccgtgaaaa actaagtgta ttcggtgacg attatgatac tcctgacggt
     5221 tcttgtatcc gtgactttat caacgttgtt gacttggcaa aagcacacgt gattgcaatc
     5281 cgccgtattt tggagcaaaa acagaaagaa aaagtagaag tatttaatat cggtacagga
     5341 cgcggcgttt cagtattgga actgattaat ggctttgaaa aagctaccgg cgttaaattg
     5401 aattatcaga ttgtaggccg tcgcgcaggt gatattgaaa aggtatgggc taatcccgat
     5461 tatgcaaacc aggaactggg ttggaaagcg gtagaaacat tagaagatac tttacgctct
     5521 gcatggaatt ggcagctgaa actccgtgaa agaggcattc agtaaaaaga tatttgtttt
     5581 aattaacata aaagtttaaa caaatcgttc atgcgatttg tttattagat gctaatcagc
     5641 ttgatctgtt tgtgagtatg tgaatatgag taaatggtac ttatgcctct ccggcataga
     5701 caggtatgat tgcatagtag ttttgtcgtg ttttattttg tgtttgtgtt gtgacggtac
     5761 tacgacggga gtcgtggtac cgttttttgt tactctttta cagcctgcct ttaaaacaga
     5821 atacgttagt tccccaatcg gtttcaggta aagttccttc cggctcgaac aatccgtata
     5881 cggaagaacc ggaaccgctc atagaggcat aaacagcacc ttgcttgtat agttcggctt
     5941 taatttctcc gatcaccgga tgctggggga atacgctgtc ttcaaaatca ttgattaata
     6001 tctctttcca ttcatttacc gggcgtttga tcgcttcttt gatcgagtat tcgggatgat
     6061 gagggtgaat attggcgaaa gcttcccgcg ttgatacgaa tacatccggt ttgatgatca
     6121 gaatctgata tccttttaag gatagtggaa tgggggagaa tatgttaccg attccttcgg
     6181 caaaggtcgg ggcgtttctg ataaagaaag cgcagtctgc tcccaaagtt gcggcatata
     6241 tttccagctg atcttcggat aaattcagct gaaagtgttc gttgagtaat ttcagcatga
     6301 aagccgcgtc tgatgagcct cctcccagtc cggcaccgga aggaatgtgt ttgtacagat
     6361 ggatctcgat aggacagagg tgaaactctt tatctaatag cagatatgct ttcaccacta
     6421 aattgtcttc cggattaccg gatatctcca ttccgtactg atgcagggag aactttttgt
     6481 ccgcttcggg gctggtccgg atttccagcg catcttcgag agcgacgggg tagaatacgg
     6541 tttcgaggtt gtgatatccg tccggacgct tctcggtaat agagagtccc aggtttattt
     6601 ttgcgtttgg gaaagtgatc atattcgttc tgaattatta tttttgaatt ttaaattatg
     6661 ggttgcgaat ttatgctatt ggtgacaaag ttactaaaat cttcattttt ccttatcttt
     6721 tcttcattat tatattctat ctttgtcatc cctttcggat tttactatgt ataaaagccg
     6781 gggatcataa attgtaaatc ataaaattgt atataagcag atggctgaac aaagaagaaa
     6841 ttcccgtaac acaaaatcaa ctaaagtaca accggtcaat gattatggtc gtatccaacc
     6901 tcaggcaccg gagctggaag aggcggtgtt gggtgcttta atgattgaga aggatgctta
     6961 ttcgctggtg agtgagattc ttcgcccgga gtcattttat gagcatcgtc atcagttgat
     7021 ttatgctgcc attactgatc ttgccgttaa tcagaagccg gtggacattc tgacggtcaa
     7081 agagcagttg agcaaaagag gtgagttgga agaggtcggt ggaccgttct atattactca
     7141 gttgagcagt aaggttgctt cttccgcaca tatcgaatat cacgcccgta ttattgcaca
     7201 aaaatcgttg gcgcgcgaat tgataacgtt taccagtaat attcaaagca aggcttttga
     7261 tgagacactg gatgtggacg acttgatgca ggaggcggaa ggcaagctgt ttgagatttc
     7321 ccagcagaat atgaagaaag actatacgca gattaatccg gtaattgacg aagcgtataa
     7381 gctgattcag aaagcggctg cacgaacgga cggtctgagt ggtcttgaaa gtggatttac
     7441 gaaactggac aagatgacct ccggttggca gaactccgac cttattataa tcgctgcccg
     7501 tcctgccatg ggtaagacag ctttcgtact ttctatggct aagaatattg ctgttgatta
     7561 tcggaatccg gtagcgttgt tctctcttga aatgagtaac gtccagttgg tcaaccgtct
     7621 tatcaccaat gtttgtgaga ttccgagtga gaagatcaaa agtggacaat tggcaagcta
     7681 tgagtggcaa cagttggact acaaactgaa agacctgctg gatgctccgc tttatgtgga
     7741 cgatactccg tctttgtctg tgtttgaact ccggaccaaa gcacgtcgtc tggtgcgtga
     7801 acatggggtg agaatcatta ttattgacta ccttcagttg atgaatgcga gtggtatggc
     7861 attcggtagc cgtcaggaag aggttagtac gatatcccgt tcgttgaaag gattggcaaa
     7921 ggagttgaac attcccatta tagccttgtc gcagttgaat cgtggtgtgg agagtcgtga
     7981 aggtattgac ggtaaacgcc ctcagttgag tgaccttcgt gaatccggag ccatcgagca
     8041 ggatgccgat atggtgtgtt ttattcaccg tccggaatat tataagattt atcaggatga
     8101 tcgtggtaac gacctgcgcg gtatggcgga aattgtgata gccaagcatc gtaatggtgc
     8161 ggtaggtgaa gtcttgctcc gattcaaagg tgagtttaca cgattctcta atccggaaga
     8221 tgatatggtt ataccgatgc cgggtgaacc tgcaggtgcc atgctggggt ctaaactgaa
     8281 tgccggtgct atgcctccgc ctccgccgga accggacttt gttccgcagg gaaataatcc
     8341 gttcggtgca acggaagggc cgttaccttt ctaaaaaaac gttcgtttgg gttgaataga
     8401 atgaccgctt agtcagatga aaataaccgc tcgatttact ccaatcgagc ggtcgattat
     8461 tttttataga gtatagccaa gttgtattct gatagggata ggtggcaaaa atgacaaaga
     8521 ataccccttt gttttttgcc actttgtcac caaccatgaa tttattgggg aataatacag
     8581 tcaggtcctt gttagtttag cttctcttga catttttctc tcaaatcgtt ctatgtcaac
     8641 cgaaaaatct tattaacttt gcgaaacttt ttgagaaaca ataaaaattt aattatatga
     8701 atatctctta taactggctg aaagagtatg tcaactttga tttgaccccc gatgaaacgg
     8761 ctgctgcgct gacctcaatc ggcttggaaa caggtggtgt agaagaagtg caaaccatta
     8821 agggtggttt ggaaggactc gtaatcggtg aagtgctgac ttgcgaagaa catccgaatt
     8881 ccgaccattt gcatatcact accgtcaatc tgggagacgg cgaacctgta cagattgtat
     8941 gcggtgctcc gaatgtagct gccggacaga aagtagtggt tgccactttg ggtaccaaac
     9001 tttatgacgg tgatgaatgc tttactatca agaagtcaaa aatccgtggt gtagaatcta
     9061 cagggatgat ttgtgcagaa gacgaaatcg gtattggtac tgatcatgca ggaatcatcg
     9121 tgttgccggc tgaagctgtt ccgggtactc tcgccaaaga ctattataat atcaagagtg
     9181 actacgtact cgaagtagat attactccta accgtgcaga cgcttgctca cactatggtg
     9241 tggcccgcga cttgtatgct tacctgattc agaatggcaa gcaggctact ttgcaacgtc
     9301 catctgtaga tggatttaag gtggaaaatc atgatttgga tatcgaagta gtggttgaaa
     9361 acagcgaagc ctgtcctcac tatgccggcg ttacggtgaa aggcgttact gtgaaggaaa
     9421 gccccgaatg gttgcagaat aaattgcgct tgatcggtgt acgtcctatt aataatgtag
     9481 tggatattac taattatatc gttcatgctt tcggtcagcc attgcattgt ttcgatgccg
     9541 gaaagataaa aggcaatgaa gtaattgtca agacattgcc ggaaggcact ccattcgtca
     9601 cattggatga agtggaacgc aagttgaacg aacgcgatct gatgatctgc aacaaagaag
     9661 aagcgatgtg tattgccggt gtattcggcg gactggattc cggttctacg gaagctacga
     9721 cagatgtatt tatcgaaagc gcttatttcc atcctacatg ggtgcgtaag actgcccgtc
     9781 gtcacggtct gaatacggat gcttctttcc gtttcgaacg tggcatcgat ccgaacggag
     9841 taatctattg tctgaaactg gctgctctga tggtgaaaga actggccggt ggcactatct
     9901 catccgaaat taaggatgtt tgcgttgcag ctccacaaga ctttatggta gaactttctt
     9961 atgagaaagt aaattcgctg attggtaaag tgattcccgt ggaaacgatc aagagcattg
    10021 ttaccagcct ggaaatgaaa atcatgaatg agacagttga cggactgaca ttagccgttc
    10081 ctccttatcg tgtagacgta cagcgtgatt gcgatgtgat cgaagatatt ctacgtatct
    10141 acggatataa taatgtagaa atcccgacta cgctgaactc cagtctgaca accaagggtg
    10201 agcatgataa atcaaacaaa ttacagaatc tggttgcaga acagttggtt ggctgtggct
    10261 tcaatgaaat actgaataat tctctgactc gtgccgctta ctacgacggt ctggagaact
    10321 atccatccaa ccatctggtg atgctgctga atccactgag tgccgatctg aactgtatgc
    10381 gtcagacatt gctgttcggt ggactggaaa gcatcgctca caatgcaaac cgcaagaatg
    10441 ccgatttgaa attcttcgaa ttcggtaatt gctattactt cgatgcggac aagaagaatc
    10501 cagaaaaagt actggctacc tattcggaag actatcactt gggtttgtgg gtgactggaa
    10561 agaaagtagc caactcatgg gcacacccgg atgaaaacag ttcggtatac gaattgaagg
    10621 cttatgtaga gaatatattg aagcgcctgg gactggattt gcacaacctg gtagttggca
    10681 atctgactga cgatattttc gctaccgcac tttctgttca taccaagggg gggaagcgtc
    10741 ttgcctcttt cggtgttgtg acgaagaaac tgctgaaagc attcgatata gataatgagg
    10801 tgtattatgc cgacttgaac tggaaagaac tgatgaaggc tatccgttca gtgaagatca
    10861 gctacaagga aatttccaaa ttccctgctg tgaagcgtga cttggcattg ttgctcgaca
    10921 agaacgtaca gtttgccgaa atcgaaaaaa tcgcttacga tacagaaaag aaactgctga
    10981 aagaagtgga actcttcgat gtatacgaag gtaagaacat cgaagcaggt aagaaatcgt
    11041 atgcggtcag cttcctgctt caggatgaaa ctcagacgct gaacgataag atgatcgata
    11101 agatcatgtc taaactggtg aagaatctgg aagataagct gaatgcaaaa ttgagataaa
    11161 tttaaaattc acaattcaaa attaatacaa accaatggga agagcatttg aatatagaaa
    11221 agccgcaaag ctgaaaagat ggggccacat ggctaaaaca tttacaagac tgggtaaaca
    11281 gatcgctatt gccgtgaagg cgggtggtcc ggaaccggaa aataacccga cactgcgttc
    11341 ggtcatcgct acttgtaagc gtgagaatat gccgaaggac aatatcgaac gtgcgattaa
    11401 gaatgcaatg ggtaaggatc agagcgacta caagagcatg acttacgaag gatacggtcc
    11461 tcacggaatt gctgtctttg tagatacgct gactgataat acgactcgta cggtagccga
    11521 tgtacgctct gtattcaata aatttggtgg taacctcgga acaatgggat cattggcttt
    11581 cctcttcgac cataaatgta tgttcacttt caagataaag gacggcatgg atatggaaga
    11641 actgatcctt gatctgattg attacgacgt agaagatgag tacgaacagg atgacgaaga
    11701 aggaacaatc actatctacg gtgatcctaa gagctatgcc gctattcaga aacatcttga
    11761 agagtgtggc ttcgaggatg tcggcggtga ttttacttat atcccgaacg atctgaaaga
    11821 ggtaactccg gaacaacgcg aaactttgga taagatgata gaacgtcttg aagaatttga
    11881 tgacgtgcag actgtttata caaacatgaa gccggaagaa ggcggaaacg aggagtaagc
    11941 ggattatgga atatgtttat agaacccagg gtacttgcag cacaaacatc gaactgaatg
    12001 tagaagatgg agttgtgaag gaagttgcct tttggggagg atgtaacgga aatcttcagg
    12061 gactttcacg tctggtaaag ggaatgaagg tagaagaggt tatcaagaaa cttgaaggag
    12121 tacgttgcag tggcagaccg acgtcctgtc ccgatcagtt gtgccatgca ctgcatgaaa
    12181 tgggatatta acggaagtct ccctttataa aatatacact ggcctccggc aattcatttt
    12241 gccggaggtt ttttattgtg ccgtaccttt ccctatttgt cggtattttg aaccaaaatc
    12301 gaccttcggt cgttatttat aagtatattt gtgctgaata aactattatg caatgatgaa
    12361 gaatattttt caagacttga aacggaaaga tcataaacgt tatttgggcg gactggatgt
    12421 ttttaaatat attggtcccg gacttttggt aactgtcgga tttattgatc cgggcaactg
    12481 ggcatcaaat tttgccgcag gttccgagtt cggctattca cttctttggg tggtcacctt
    12541 atccactatc atgttgattg tcctccagca taatgttgct cacttgggga ttgttacggg
    12601 gctttgcctt tcggaagccg ctacgaaata tactcctaaa tgggtatccc gtcctatttt
    12661 gggtacggcg gtattggcgt ctatttctac ttcattggct gagattctgg gaggagccat
    12721 cgcattggag atgctgtttg atatgcctat tatgtggggg gcggtgctga ccacactttt
    12781 tgtctccatc atgctcttta ccaactccta taaaaagata gaacgttcca ttattgcttt
    12841 tgtctcggtg atcggtcttt catttattta tgaattgttt ctggtagaaa tagactggcc
    12901 ggctgcgacg atgggttggg tgacgcctgc tttcccgaag ggtagtatgc tgattattat
    12961 gagtgtgctg ggagcggttg tgatgcctca taatctgttt ctgcattcgg aagtaataca
    13021 gagtcacgag tataataaga aagacgatgc gtctatcaag aaagtattga aatacgagtt
    13081 gttcgatacg cttttctcga tgatcgttgg ctgggcaatt aacagtgcta tgattctgct
    13141 ggctgctgct actttcttta aaagtggtat tcaggtggaa gaattgcaac aagccaaatc
    13201 actgcttgaa cctttgttgg gaagtaatgc ggcaatcgta ttcgcattgg ctctgttgat
    13261 ggcaggtatt tcgtccacca taacaagcgg aatggcggca ggttctatct ttgcaggtat
    13321 ctttggagag tcatatcata ttaaagacag tcactcgcag gtaggagtaa tcctttcgtt
    13381 gggaattgcg ctgttgctga ttttctttat tggtgatcca ttcaagggat tactgatttc
    13441 gcagatgata ttgagtattc agttgccttt cacggtattc ctgcaagtag ggttgacttc
    13501 atcccgaaag gtaatgggga attatgtcaa tagccgttgg agtacttttg tattatatgc
    13561 tattgcagtc attgtttcgg tattgaatat aatgctgctg ttttcataaa acgaacataa
    13621 atctataaac tataaaatga tgaagattat tacttataat gtgaacgggc ttcgtgctgc
    13681 cgtttctaaa ggtttgccgg aatggctggt gcaggagaat ccggatattc tttgtctgca
    13741 agagacaaaa ctacagccgg accaatatcc ggcagaagta tttgaagctt tgggttacag
    13801 ggcttatctc tattctgcac aaaagaaggg atacagcggt gtggcgatcc ttactaagca
    13861 ggaacccgat catgtggaat atggtatggg gatagaagct tatgacaatg aagggcgttt
    13921 tatccgtgcg gattttggcg acttgtccgt agtcagtgtt tatcatcctt cgggaacgag
    13981 cggagacgaa cggcaggcat ttaaaatggt gtggctggaa gactttcaga aatatgtgac
    14041 agagctgcgc aagactcgtc cgaaccttat cctttgcggt gactataata tctgtcatga
    14101 gccgattgat attcatgatc ctgtccggaa tgccacgaac agcggcttcc tgcccgaaga
    14161 acgggaatgg atgactcgtt tcctttctgc aggatttatt gattctttcc gtctgctcta
    14221 tccggagaaa caggagtata cgtggtggag ctatcgtttt aattcgcgtg cc
//
