LOCUS       c00103_gnlPro..        12788 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DIGMNBLD_103.
ACCESSION   c00103_gnlPro..
VERSION     c00103_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:19:21
            Original ID  :: gnl|Prokka|DIGMNBLD_103
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12788
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12788
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[16:2788]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      17..2788
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..12788
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12788
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             17..1996
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 200.6; E-value:
                     1.5e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_1"
                     /sec_met_domain="FAD_binding_2 (E-value: 3e-62, bitscore:
                     200.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 6.5e-37,
                     bitscore: 116.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLFTRYEMQDVVIIDGRARGIIAKNLITGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAIKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHIMWEYVGMGRTAEGLKKGIAELKAVRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLIKEPLVYEAIKVQTRNYKS"
     CDS             2033..2788
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_2"
                     /sec_met_domain="Fer4_7 (E-value: 8.8e-13, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 6.3e-26, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.9e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             2950..4179
                     /locus_tag="ctg103_3"
                     /transl_table=11
                     /translation="MNKLLLIWIVVLLTSCITNQENARDTLFVNLTDATDSQSLKLSDF
                     GNTVRYVPLETNEVCLIGDNPHIALLEDKIVISTTDQCFLFHKQTGKYICSIGHIGDDP
                     SGYSSTNYWIDDAGLFYFFRAPDQLLKYNQKGEMTGKIQIPHIPAAPGYFAFSNSTIIA
                     HCNSNIGMEPGNSLLFLNSFGEKLDSIPSLLKSPSIPSPDNISSLSILKRGAGFFGNLG
                     RRGVMIIKDKEQGELLLPLYNPSLWSSENELRFRETFTDTIYTVKNKKLYPYMVFHTDT
                     DHSSANPLWYSNPQSIYVAYVLENTHSVFFQYVKNKQVYNGLYNKETQQTKFAKCQQFI
                     VDDLTSEQELKVDLSALCSYKGEYGFILEAASIPDASQKQSDNKNENIPHWMSQLDEDA
                     NPVIAIVSDK"
     CDS             complement(4251..5777)
                     /locus_tag="ctg103_4"
                     /transl_table=11
                     /translation="MRTKRAFKEFCVLGGLASSVCGVAQERPNIIVFLVDDMGLMDTSV
                     PFIADESGQPVRHPLNDWYHTPNMERLAKQGICFSTFYAQSVSSPSRASIMTGQNATRH
                     GVTNWINAESNNRNPFGPPQWNWKGLRKDMPTMPRVLQQAGYKTIHVGKAHFGCMGSEG
                     ENPLNIGFDVNIAGSGIGHPGSYYGEWGYGHIKGQKIRAVPDLEKYHGTDTFLSEALTI
                     EANREITKAVEEKRPFYLNMAHYAVHSPFQADKRFLSRYTDPDKNEQARAFATLIEGMD
                     KSLGDIMDQLEKLGIAENTLILFLGDNGGDAPLGDERGYGSSAPLRGKKGTEFEGGMRV
                     PFIAAWAKPEKKSKVQKNLPIGVGSMQTQVGTIMDIYPTVLSVAGCEVPQNYVIDGFDL
                     KKQLSGKVDKKRPESFLMHFPHAHRGSYFTTYRMGDWKLIYYYLPETPKQPKALLYNLK
                     DDPEERNELSAAHPDQCREMIREMSARLEKEGALYPVDKQGNELKPFVYF"
     CDS             complement(6125..6967)
                     /locus_tag="ctg103_5"
                     /transl_table=11
                     /translation="MSSICQGTWDCQNCPKAVDNAIIHTTHTRGYHQPARKCEDNFILF
                     LIKGELLVNSQEYAGTMLKAGEFILQAIGSKYEMLAMTECECIYYRFIQPELFCDFRFN
                     HIMKDVPSPLIYSPLKIIPELKYFLDGSKSYLSESKVCRDLLSLKRKELAFVLSYYYSD
                     YDLASLVHPLSKYTTTFEYFILQNYKKVKTVEELAQLGGYTVSTLRRIFNNVFHEPVYE
                     WMQARRKEGILDDLNNSEYSISEICYKYGFESLPHFSNFCKKFFGASPRMLRTSKKNV"
     CDS             complement(7308..8291)
                     /locus_tag="ctg103_6"
                     /transl_table=11
                     /translation="MKKVLLAIAAVATITSCSQNEEFENPAQNAEINFSTIVSKSTRAV
                     IIENKDFKKFTAYGYSHGETNFTGVVTSTIMSSAEYTKGEDGGWTTSGRYYWPTSGKVT
                     FFGYGGVATATYAKEDGKFPTLKYTVLTDVNKQEDLLVAQQANKSKENNNPSVNLNFKH
                     ALAQVYFKLKGNDADLTYTVSKIELNKVRTEGTFTYGGDPDTSIGQWAVEDNASTGNYA
                     ITLNDQKVIGEAEATILNDALTQVMILMPQSLAGVEVKVTYSAEKGGLEVHSASEPVTV
                     KLTGNWEAGSKTAYVLSLNGDAINLTGSSDDTSWSEKTDVNTDVNK"
     CDS             complement(8344..9300)
                     /locus_tag="ctg103_7"
                     /transl_table=11
                     /translation="MQDTRYILLVLLSSLLMLTGCSRRELLDDYPVSGVDIKLDWNGVT
                     DKLPEGVRVIFYPKSAEGRKIDTYLSVRGGKVKVPPGRYSVVAYNYDTETVQIRGEEAY
                     ETIEAFTGYCNGLGIAGTEKMVWGPDPLYVVQINDLHIANSEEELLLDWKPKLVVKTYS
                     FKIKVEGLEYVSSIVGSVEGMAGCYCLGRCCGMMNDAPIYFEAQGCSGEVTGSFTAFGL
                     PEGAMSRASLAIKFTLAFVKVDNTVQKIEVDITDVIVNSESGEGGGNDEPSKDIELPLD
                     DDEVKVDKPENSSGGDGGIGGDVGDWGEEEEVPLPVI"
     CDS             complement(9308..10585)
                     /locus_tag="ctg103_8"
                     /transl_table=11
                     /translation="MQHGIYTCVILMAFLALSESVYAVVPVFTIASDTIRRVVIYFDQE
                     ETDVDSCYKTNNQEVNVLDSLLEERINSRYITALNVVTFVSPDGDSVYNAALSVRRNNS
                     MREFLRQRYPYVDVEKIKLTSEGEDWSELRKLVASDSDLPDREEVLMLIDYHRDNIVKR
                     KELLQKLNQGMAYRYIVRNVLPKLRRAEITVVREVPEMEKNTFEPVSSVSGLFVSKQEE
                     ALPSDQPDKPEGESKESMAYEVVVSEAEGPVESKTVLAVKNNLLYDLALAPNLEVEIPV
                     GKRWSLNAEYKCPWWLNSKHNFCYQLLSGGVEGRCWLGNRQKRNRLTGHFVGLYAEGGI
                     YDFQWKGDGYRGDYYGAAGVTYGYARQLARHLSLEFSFGIGYLTTEYKKYTPYEGDIVW
                     TTSGRYNFIGPTKAKVSLVWLIKRGR"
     CDS             complement(10857..11354)
                     /locus_tag="ctg103_9"
                     /transl_table=11
                     /translation="MALEYVVTKRVFGFDKDKNEKYVAKSVRSGRVSFSKMCGKVSRLC
                     GVHRKVVDLVVSGLVDMMAEDIDDGKSVQMGEFGIFSPTIRAKSADDEKEVSSKSIVQR
                     KILFYPGKIFKTTLDDMSITRRAELDTDYTDGSSNNGSGSVKPNPGGDGGKGDEEAPDP
                     TV"
     CDS             complement(11715..11840)
                     /locus_tag="ctg103_10"
                     /transl_table=11
                     /translation="MRKHTFLFIIFLYVGICIQVKATDQRGEYLVIGKDTLEMFT"
     CDS             complement(12314..12535)
                     /locus_tag="ctg103_11"
                     /transl_table=11
                     /translation="MRGILSFAALAAMYFPGCTTSKNAVHCLSRWIKGCNPLVKELIPT
                     GYLPYNHRFLTSKQYKIITKHLGDPYED"
ORIGIN
        1 aattgtaaat aatattatga tcaagataga ttcaaaaatt ccagaaggcc cggtggctga
       61 gaaatggacc aactataaag ctcaccagaa attggtgaac cccgctaata aacgccgttt
      121 ggatatcatc gttgtgggta cgggtctggc aggtgcttct gctgctgcat ccctcggtga
      181 aatgggtttc agagtattca acttctgtat tcaggactct ccgcgccgtg cacactctat
      241 cgctgcacag ggtggtatca atgctgcaaa gaattatcag aatgatggtg actccgttta
      301 ccgtctgttt tacgatacag taaaaggtgg tgactatcgt gcacgtgaag ccaacgttta
      361 ccgtctggcc gaagtgtcca acgctatcat cgaccaatgc gtggcacaag gtgttccttt
      421 cgcacgcgaa tacggcggta cactggacaa ccgttctttc ggtggtgcac aggtatcacg
      481 tacattctac gctaaaggcc agaccggtca gcaactcttg ctgggtgctt actccgcact
      541 gagccgtcag gtaaacgtag gtacggtgaa gttgttcacc cgttatgaaa tgcaggacgt
      601 tgtgatcatc gacggacgtg ctcgcggtat catcgccaag aacttaatca ccggtgaact
      661 ggaacgtttc gctgcccacg ccgtagtgat cgctaccggt ggttacggta acgcttactt
      721 cctgtctacc aacgctatgg gttgtaactg tacagctgct atctcttgct accgcaaggg
      781 tgctgtattc gcaaaccccg catacgttca gattcacccg acttgtatcc cggtacacgg
      841 tgacaagcag tccaaactga ctctgatgtc cgaatctctg cgtaacgacg gtcgtatctg
      901 ggttccgaag aagaaagaag acgctatcaa attgcagaaa ggcgaaatca agggaagcga
      961 tattcctgaa gaagaccgcg actattatct ggaacgccgt tatccggcat tcggtaacct
     1021 ggttccacgt gacgttgcca gccgtgcagc taaagaacgt tgcgacgcag gtttcggtgt
     1081 gaacaacaca ggtctggccg tattcctcga tttctctgaa gctatcaacc gcctgggcat
     1141 cgatgtagtg cttcagcgtt atggtaacct cttcgatatg tatgaagaaa tcactgacgt
     1201 taatccgggc gaactggcaa aagaaatcag tggtgtgaaa tattataatc cgatgatgat
     1261 ttatccggct atccactaca caatgggtgg tatctgggta gactacgaac tgcagactac
     1321 catcaagggt ctgttcgcta tcggtgaatg taacttctcc gaccacggtg caaaccgcct
     1381 cggtgcttcc gcattgatgc aaggtctggc cgacggttac ttcgtattgc cttacactat
     1441 ccagaactat ctggcagatc agattactgt tcctcgtttc tctactgacc ttccggaatt
     1501 tgccgaagca gaaaaggcag ttcaggctaa gatcgacaag ttcatgagca tccagggtaa
     1561 agaatcagtt gattctatcc acaagaaact gggtcacatc atgtgggaat acgtaggtat
     1621 gggacgtacg gcagaaggcc tgaagaaagg tatcgccgaa ctgaaagcag tccgcaagga
     1681 attcgaaacc aatctgttta tccccggttc taaggaaggt atgaacgttg agctcgacaa
     1741 ggctatccgt ctgtatgact tcatcactat gggcgagctc gttgcttacg acgcattgaa
     1801 ccgtaatgaa agttgtggtg gtcacttccg tgaagaatac cagactgaag aaggagaagc
     1861 aaaacgtgat gacgaaaact tcttctacgt agcttgctgg gaatatcagg gtgacgatga
     1921 aaaggctcct gtattgatca aagaaccgct ggtatacgaa gctatcaagg ttcagacccg
     1981 taactacaag agctaatcgg tgaagttaaa catttaaaag aattagacga aaatggataa
     2041 aaatatatca tttacactga aggtatggcg tcaagcaggc ccgaaggcta aaggcgcttt
     2101 tgaaacctac caaatgaaag atatccccgg tgatacttcc ttcctcgaaa tgctggatat
     2161 tctgaacgaa cagctgatca gcgaaagaaa agaaccggtt gtattcgacc acgactgccg
     2221 cgaaggtatt tgcggtatgt gttctcttta catcaacgga catccgcacg gtcctgcaac
     2281 aggtgctact acttgccaga tttacatgcg tcgtttcaac gatggtgaca ccatcactgt
     2341 tgagccttgg cgttcggccg gtttccctgt catcaaggac ttgatggtag accgtactgc
     2401 ttatgacaag atcatgcagg ccggtggtta tgtaagcgtt cgtacaggcg ctccgcagga
     2461 tgccaacgct atcctgatcc cgaagcccat tgctgacgaa gctatggatg ccgcttcttg
     2521 tatcggttgc ggtgcttgtg tagctgcttg taagaatggt tctgccatgt tgttcgtttc
     2581 ggcaaaggtc agccagttga acttgcttcc gcaaggtaaa ccggaagctc tgcgccgtgc
     2641 gaaagctatg ttgtccaaga tggacgaact cggattcggt aactgtacca acacccgcgc
     2701 ttgcgaggct gaatgtccga agaacatctc tatcagcaac atcgcccgcc tgaaccgcga
     2761 cttcatcatc gctaaactga aagactaagc gtgagcttga tttgattaat agcataaatc
     2821 ccccgtcggc gttagctggc gggggatttt ctttttactg accaattatt tatagatagc
     2881 ttgttcatta tccgtttttt attcttttct ttgtgacata aggccagaca atcaaataaa
     2941 ttaaatacga tgaataaatt attgctgata tggatagtag tcttactaac ctcatgcatc
     3001 acaaatcagg aaaatgccag ggatacatta tttgtaaatc ttacggatgc aactgattcc
     3061 caaagcctaa agttatctga cttcggaaat actgtacgtt atgtaccttt ggaaaccaac
     3121 gaagtatgcc tgataggaga caatccccat atagcgctgc tggaagataa gattgtgatt
     3181 agcactacag accaatgttt cttattccac aaacagaccg ggaagtatat atgcagtata
     3241 ggccatatcg gtgatgatcc aagtggatat agctcgacaa attactggat agatgatgca
     3301 ggtctttttt acttctttcg cgcaccggac caactgctaa aatataatca gaaaggagaa
     3361 atgaccggga aaattcaaat tccacatata cctgctgcac ccggctattt tgcattttcc
     3421 aactctacca ttatcgccca ttgtaatagt aatataggaa tggaacccgg taactctttg
     3481 cttttcctca actcctttgg ggaaaagctg gattcaattc ccagtttatt aaaatcacct
     3541 tccatccctt ctccggataa tatatccagc ctttctatac taaaaagagg agcaggtttc
     3601 tttggaaatc tgggaagaag aggggtaatg attatcaaag ataaggagca aggagagtta
     3661 ctgctgcctc tctataatcc tagcctatgg tcgtccgaga atgaattacg tttcagagaa
     3721 accttcacag acacgatata cacagttaaa aacaagaaac tatatccata tatggttttt
     3781 catacagata cagatcattc atccgccaat cctttatggt atagtaatcc gcaaagtatc
     3841 tacgtagctt atgtattgga aaacacacat tctgtatttt ttcaatacgt aaaaaacaaa
     3901 caagtctata atggtttgta taataaagaa acacagcaaa ctaagtttgc aaagtgccag
     3961 caattcattg ttgacgatct cacttcagaa caggaactga aagttgacct gtcggcattg
     4021 tgcagttata aaggagaata tggatttatt ctggaagctg ccagtattcc tgatgcttct
     4081 caaaaacaat ctgacaataa aaatgagaat attccccatt ggatgagcca attggatgag
     4141 gatgccaatc cggtcatagc aattgtatct gacaaatgat atataattct gtctgttttg
     4201 cctaatagat atgctttggc aaaacagaca gttgaaatag tagcacctat ttaaaagtaa
     4261 acaaaaggct tcaactcatt tccttgttta tccaccggat aaagagctcc ttccttttct
     4321 agccgggcgg acatttcccg aatcatctct ctgcattgat ccggatgtgc ggcagacagc
     4381 tcattccttt cttccggatc gtctttcaga ttgtaaagca aggctttggg ttgtttcgga
     4441 gtctcgggaa gataataata aatcagtttc cagtcgccca tgcgataggt ggtgaagtag
     4501 ctgccgcggt gtgcgtgagg gaagtgcatc aggaaagact cgggacgctt cttgtccacc
     4561 ttaccgctca gttgcttttt cagatcgaat ccgtctatca cgtagttttg gggaacttcg
     4621 catcctgcca cagacagaac agtcggatag atatccatga ttgtgcccac ctgtgtctgc
     4681 atacttccta ctccaatagg caagttcttc tgtactttgc tcttcttctc aggctttgcc
     4741 caagctgcga tgaaaggaac acgcatacca ccttcaaact ccgtcccctt tttacctctc
     4801 agcggagcgg aagaaccata gccacgttca tctcccaatg gagcatcacc accgttatct
     4861 cctaaaaaga gaatcagcgt attttcggca attcccagct tttcgagttg gtccatgatg
     4921 tcgcctaatg atttatccat gccttctatc aatgtagcaa aagctcttgc ctgctcgttc
     4981 ttatccgggt cggtgtagcg tgacaagaaa cgtttgtctg cctggaaagg tgaatgaact
     5041 gcgtaatggg ccatattcag atagaaaggt cgtttttctt ctacggcttt ggtgatctcc
     5101 cgattcgctt ctatagtcag cgcttcactc aagaaggtat ctgtaccgtg atatttctcc
     5161 aggtcaggaa ctgctctaat cttctgtccc ttgatatgcc cgtatcccca ttcgccataa
     5221 tagctgccgg gatggccgat gccggaacct gcgatattta catcaaagcc gatattcagc
     5281 ggattctctc cttcgcttcc catacagccg aaatgtgcct ttcctacatg aatggtttta
     5341 tatccggctt gttgcaggac tctcggcatg gtaggcatat cttttctgag acctttccag
     5401 ttccattggg gcggtccgaa aggattccgg ttgttgctct cagcattaat ccagttagtg
     5461 actccatgcc tggtcgcatt ctgtccggtc atgatggaag ctctggaagg ggaactcacg
     5521 ctctgtgcgt aaaaagtaga gaaacaaata ccctgtttag ccagtctctc catattcggg
     5581 gtatgatacc agtcattcag cggatgacgc accggctgac cactctcatc tgcgataaaa
     5641 ggaaccgacg tatccataag tcccatgtca tctacaagga aaacaataat attcgggcgc
     5701 tcctgagcta ctccgcaaac ggaagatgcc aaaccaccca atacacaaaa ttccttaaaa
     5761 gctcgttttg ttctcattac atagtattta tgatttatat cctagttatt gtacgtgcca
     5821 taatagattt caaactcaga ctctcttctg attacacaaa agagtattag aaaaatatcc
     5881 tattatcttt cattcattca gcataatcta tcatgttatt attctgcttt gaaacctgat
     5941 tttaattcgt tgaaataaaa agtttaattt ccgtatccgc cttatcatgg ctttatttga
     6001 agtgatctga ctttataata aagatgtatt agactggttt taaaggaaac agctagcaat
     6061 atacaacaaa tgtactacac ccacaaagaa aaaaatagtt tttgactttc tctctgaaaa
     6121 attatcagac gttcttcttg cttgttctaa gcatacgtgg agaagctcca aagaacttct
     6181 tacagaaatt ggagaagtga ggcagagact caaaaccgta tttatagcat atttcggaga
     6241 tactgtactc agagttattc aagtcatcca aaataccttc cttacgtcgc gcctgcatcc
     6301 attcgtatac cggttcgtgg aatacattat tgaagatacg ccgcaaggtg ctgacggtat
     6361 aacctcccag ttgagccagt tcttctaccg tttttacttt cttatagttc tgaaggatga
     6421 agtattcaaa agtggtggtg tatttcgaga gtggatgcac caaactagcc aagtcataat
     6481 ccgaataata gtagcttagc acaaacgcca gttctttgcg ctttaaagac agcagatccc
     6541 ggcagacttt actttcactc aaataggatt tggaaccatc caaaaagtat ttcaattcag
     6601 gaattatctt taaaggagaa tagataagcg gagaaggtac atccttcatg atatgattga
     6661 aacggaagtc acagaatagt tccggctgaa taaaacgata atagatacat tcgcactcgg
     6721 tcatcgcaag catctcgtat tttgaaccaa tagcctgaag aataaattca cctgctttca
     6781 acatcgtacc tgcatactcc tgactattaa ccaagagctc tccctttatc aaaaaaagga
     6841 tgaaattatc ttcacacttc cgggctggtt gatggtagcc ccttgtatgg gtagtgtgaa
     6901 tgatagcatt gtctacggct ttcggacagt tctgacaatc ccaagtaccc tgacagattg
     6961 atgacatata tttgtgttgg cgtttgattt gttcctgttt gcaacaaaaa tatatgaaat
     7021 cttttacatg gcaatagaaa agggaggaaa agtgaaaaag aggttatttt tacatttttt
     7081 ttgtaatata aaaaggagag tatttttact tttaaaaaag ctattcacta ttttatatta
     7141 tcaaaaattc ctaaatataa attttacact agattttgac tttcaaacat aactagaatt
     7201 aatttaaaat taggggacta tctgaaatat catcagataa agtccccgga atattttatt
     7261 ttcaaataat caaaacagac atttgtttct taataaatac gtccaaatta tttatttaca
     7321 tcagtattta catctgtttt ttctgaccat gaagtgtcat cagaagaccc tgtcaaattt
     7381 atagcatcac catttaaaga taatacataa gctgttttag aaccagcttc ccagttccct
     7441 gtcaatttta ccgtaacagg ttcactcgca ctatgaactt caaggccacc cttttctgca
     7501 ctatatgtta ctttaacttc tactccggct aaggattggg gcataagaat cattacctgt
     7561 gttaaggcat catttaaaat tgtggcttct gcttctccta taactttctg atcatttaat
     7621 gtgattgcat aatttccagt agaagcgtta tcctctacag cccactgtcc aatagatgta
     7681 tcaggatcac ccccatatgt gaaagtacct tctgttctta ccttatttag ttcaatctta
     7741 gaaactgtat atgtaaggtc tgcgtcatta cctttcaatt taaagtaaac ttgagccaat
     7801 gcatgcttaa aattcaaatt aacagaagga ttattgtttt ctttactttt attagcttgc
     7861 tgtgctacta gtaagtcttc ttgcttatta acatccgtta acacagtata ttttaaagta
     7921 ggaaacttac cgtcttcttt agcatacgtt gcagtagcca ctcctccata tccaaagaaa
     7981 gtaaccttac cagatgtcgg ccaataataa cgccctgatg tagtccagcc tccatcttca
     8041 cctttagtat attcagcact agacattata gtagatgtaa caactcccgt aaaattcgtt
     8101 tcaccatgag aatacccata ggctgtaaat ttcttaaagt ccttattctc tattataacg
     8161 gctcttgtag atttacttac aatagtacta aaatttatct ccgcattctg tgctggattc
     8221 tcaaattctt cattctgtga gcagcttgta attgttgcaa ctgctgcaat cgccaataat
     8281 acctttttca taatcgtatt tttttaagtt tataatattg ttatattttg cttatgcttt
     8341 atctcaaatt acgggcaaag gcacctcctc ctcttccccc caatcaccaa catcaccgcc
     8401 aataccacca tcaccaccag acgaattttc cggcttatca accttcacct catcatcatc
     8461 aagcggtaac tctatatctt tagaaggctc atcgttgcct cccccttcac cactctccga
     8521 attaacaatc acatccgtta tatcaacctc tatcttctgt accgtattat ccaccttcac
     8581 aaatgccagc gtaaacttta tagcaagact tgcccgactc atcgcccctt ccggtaaccc
     8641 aaaagcagta aaactacccg ttacttcgcc cgaacaccct tgcgcttcaa agtagatagg
     8701 agcatcgttc atcatcccgc aacatctgcc caaacagtaa caacccgcca taccttccac
     8761 actgcctaca attgaagaaa catattccag cccttccacc ttgatcttga aagaataggt
     8821 ctttaccact aatttcggtt tccaatccag tagaagctct tcttcactgt tcgctatatg
     8881 taaatcattg atctgcacta cgtataaggg atcaggtccc cataccattt tttccgttcc
     8941 cgctattccc agaccattgc aatagcctgt aaatgcttca atcgtctcat aggcttcctc
     9001 tcctctgatc tgcaccgttt cagtgtcgta gttgtaagcc actaccgaat aacgccccgg
     9061 cggcaccttt acttttccac ctcttactga aaggtatgta tcaatctttc tgccttccgc
     9121 actcttcgga taaaaaatca cccgaacccc ttccggcaac ttatcggtaa caccgttcca
     9181 atctaacttt atatctaccc cgcttacggg ataatcatcc aatagttcgc gacggctaca
     9241 tccggtcagc atcagcagcg aggacagaag cacaagaagt atgtatcttg tatcttgcat
     9301 aacgtcctta tctccctctt tttatcagcc ataccagaga gactttcgcc ttggtaggac
     9361 ctataaagtt ataacgtcca ctagttgtcc acacgatatc cccctcgtaa ggagtatatt
     9421 tcttatattc tgttgtcaga tacccgatgc cgaagctaaa ttcgagcgac agatggcgag
     9481 ccagttgccg cgcatacccg taggtcactc ccgcagctcc gtaataatcg ccccgataac
     9541 cgtcgccctt ccactggaaa tcgtaaattc caccttcagc ataaagccca acaaaatgcc
     9601 ctgtcaaccg gttgcgcttc tgacgattgc ccaaccagca acgtccttcc actcctcccg
     9661 aaagaagctg ataacagaaa ttgtgtttac tgttgagcca ccacgggcat ttgtattcag
     9721 catttaaaga ccaccttttg cctaccggaa tctctacttc cagatttggc gccaacgcca
     9781 agtcgtacaa cagattattc ttcactgcaa gcaccgtttt actttcaacc ggcccttctg
     9841 cctccgacac taccacctca taagccatac tctctttact ttctccctcc ggcttatcag
     9901 gttgatcgct cggaagcgcc tcttcctgct ttgaaacaaa caatccggag acagaagata
     9961 ccggttcaaa agtattcttt tccatttccg gaacttcccg gacaaccgta atctcagcgc
    10021 gtctcaactt aggtaacaca ttgcggacaa tatatcggta agccattccc tgattcaact
    10081 tctgcaacag ttcttttcgc ttcacgatgt tatcccgatg ataatctatc aacatcaaga
    10141 cttcttcccg gtccggcaag tctgaatccg acgccaccaa cttacgaagt tcagaccagt
    10201 cttctccttc agaagtaagt ttaatctttt cgacatcaac atacggataa cgttgcctta
    10261 agaactctct catcgaattg tttcttcgga cagataatgc ggcattgtaa accgaatctc
    10321 cgtcaggcga tacaaaagtg accacattga gcgcagtgat atatcttgaa tttattcttt
    10381 cctcaagcaa agaatctaaa acattaactt cttgattatt agttttataa caggaatcaa
    10441 catctgtttc ttcctgatcg aaatatatca ccacccgcct gatagtgtca ctcgcaatcg
    10501 tgaaaaccgg aaccactgca tacacacttt ctgataaagc aagaaatgcc atgagaataa
    10561 cgcatgtata gattccgtgt tgcataattg ttcgtttctg tgaacaaata tagaagttat
    10621 aatataaact aaatcatact agcagaacaa aaaacaggac atggaaggtt ctgtgaaacg
    10681 attggaacga atttgcaagt ttagaagcaa ataaggagga aacaatagat acaccaaggc
    10741 attatataaa gaaaaaatgc acagaaaatc gagtataacc gattatctgt gcatttgcaa
    10801 cttttcaata agcctttccc acgctgtctg ctacctaaaa agaaagtaca gaagatttat
    10861 acagtcgggt ccggcgcttc ttcatcaccc tttcctccgt ctccaccggg attaggtttt
    10921 acgctaccgc tgccattgtt actacttccg tccgtatagt ccgtatccaa ctccgcacga
    10981 cgggtaatac tcatatcatc caacgtggtc ttgaatattt ttccaggata gaaaaggatc
    11041 tttctttgga cgattgactt agatgatact tccttctcgt catccgcact cttagcgcga
    11101 atggtagggc tgaagatgcc gaactcaccc atctgaacac tctttccgtc gtcaatgtcc
    11161 tccgccatca tatcgacaag accgctgacg accagatcca caactttgcg gtgaactcca
    11221 caaagacggc tcaccttgcc acacatcttg gaaaaactta ctctgccgga acgaaccgac
    11281 tttgctacat acttttcgtt tttgtccttg tcaaaaccga acactctttt tgttactaca
    11341 tactctaaag ccataattgt taaagtttaa atggttaaaa aaataaaggt tatctgtttg
    11401 ccattccgtt ttgtctgaat gactctgcaa agatataaca gggcgcaaac cgtccagtcc
    11461 cctttagtcc cccttgtgtc tcctttcaat ggctttaaag cagtaaatat cctaaagtaa
    11521 ttcgcttatt ttcaatcgac tatacagatg aatatttttt ttccaaagtg cgttcattgc
    11581 tgtttctcca aatagagtct gtcggtttcc agtctccata taccgacata cccccgcccg
    11641 caatcagtag agaaggagcg cttcgaaata caattcttta cctgcttact cagagtctca
    11701 ctatctccca atggtcaagt aaacatttcc aatgtatctt tacctatgac gagatattcc
    11761 cctctttgat ctgttgcctt aacctgtatg cagatgccaa catacaaaaa gataataaat
    11821 agaaaagtgt gctttctcat agctttataa ttttagaaaa ccgaatatac atatatataa
    11881 tagagcaata atactcattt cggtatttat catatgcgaa taaacgaatt attctgtttg
    11941 ctcaaataga attacgtaca aattagctgc attatagtat aaccaacgaa aaagcaacat
    12001 gatactttgc catacaaaac ggtctatgag agaaaggtaa aaatagtcat gcaaatttac
    12061 caatatacta atccaatgaa tacgatactg ccttctcccg atttacccac aatgaaaaac
    12121 atagacactg tatactaaaa ccgtatttga gtttctaata aattctttca tcgtttatta
    12181 gaaacggttc ccaagtttat taaaaacacc gatacgcctt tcaaatctct ttttcttgaa
    12241 tttatgcaac aaaaaaggct gcaaactccg taaaagtttg cagccttttg ctcattgccg
    12301 ggctacttat gccctaatcc tcataaggat ctcctagatg ttttgttata atcttatact
    12361 gttttgatgt caaaaaccga tgattgtacg gcaagtaacc tgtcggtata agttctttga
    12421 ccaacgggtt acaaccttta atccatcggc tgagacaatg caccgcattt ttactcgttg
    12481 tacatccggg gaagtacatc gcagccagtg cagcaaaaga taagattcct ctcattcgtt
    12541 tctaagtttt gatttgagtt ttattgttgt tattacgact acaaatatac aacataaaaa
    12601 agcctttgtc aagtcctcaa gaccttcgag cgttaataac aaattaaaga actggagtac
    12661 tggcacataa gcaaggattg catcgtcaat gactaacaag tttgttacta acaactttgt
    12721 tagtaacaaa cttgttagtt aataaaaagg ctgagattcc tcaattcaga cccattgtgt
    12781 gcgataac
//
