LOCUS       gnlProkkaHDDIGPKE_10   21666 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HDDIGPKE_10.
ACCESSION   gnlProkkaHDDIGPKE_10
VERSION     gnlProkkaHDDIGPKE_10
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 00:55:57
            Original ID  :: gnl|Prokka|HDDIGPKE_10
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 7644
            Orig. end    :: 29310
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21666
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11666]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11666
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21666
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21666
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             1547..3823
                     /locus_tag="ctg10_10"
                     /transl_table=11
                     /translation="MLDMIKCSTGGAYYARGEWVPADGNAPAALAAKGFDAAAVATAKT
                     GTMAYNIMQAHNTSGDAENLKIKFDAMASHDITFVGIIQTARASGLEKFPIPYVLTNCH
                     NSLCAVGGTINEDDHRFGLSAAKKYGGIFVPPHMAVIHQYMRERFAGCGKMILGSDSHT
                     RYGALGTMAIGEGGGELAKQLLGRTYDVARPGVVAIYLTGSLPAGCGPHDVAIALVGKL
                     FKSGYVKNKVMEFVGPGIASLRQDTRNAIDAMTTETTCLSSIWETDEVTQRFLAVHGRA
                     ADYKKLAPADLAYYDGVVEVDLSAIRPMIALPMHPSNAFTIEELNANLEDILHACEQDV
                     QKLIGRKDVQLDLCSKIENGKLRVDQGVIAGCAGGLYDSIYEAASILKGHTGGCGDYAL
                     SVYPGSQPIMMELVRTGVIGELMASGATIRTAFCGPCFGAGDVPANGALSIRHTTRNFP
                     SREGSKPGSGQLAGVALMDARSIAATTANGGILTPATDIDYDPTVPEYQYDASSYDTRV
                     YQGFGKGDYDALLKFGPNIKDWPEIAPLGDNLLLKVASYITDPVTTTDELIPSGETSSY
                     RSNPLGLAEFTLSRKDPEYVGRAKAVQAEENARRAGAGDAALLAKVNAVPGCEQLSWND
                     IQIASTIFAVKPGDGSAREQAASCQRVLGAGANIVTEYATKRYRSNLINWGMLPLQLAG
                     ATPFGLGDYVLIPNVREALKGDLQNIKAYVLGDTVKEFELYMAPLTTDERQILADGCLI
                     NFYKH"
     CDS             3838..4698
                     /locus_tag="ctg10_11"
                     /transl_table=11
                     /translation="MSCDLHIHSTCSDGAVPIERLAPIAARTGLHAIALSDHDTLLSAQ
                     YAYAHTGQDGVELIPAVELTGYDFERQHRVHLLCYYPDVDCPALREHCAIMKERRNACA
                     LQSAKELEQLYPQFTTDLAWETTKASGVLFKSGLMQALELLGLTDGSIYGETYHKLFGW
                     NPRGIVLHSPEYLPVRQVLATAKASGGAVVFAHPTVYKSMPLLRELAAEGAVDGIEVYH
                     PSNSPEDSAECLALCKQYGLVATAGTDFHGRNHKHPHPIGTCTAPDEAAAQLRAIAEKR
                     KRERT"
     CDS             4704..4967
                     /locus_tag="ctg10_12"
                     /transl_table=11
                     /translation="MSKEFSFPNKGTCSKQTNFVLNDDHTIASIEVIGGCNGNLKGICQ
                     LLTGMKAEDAIARLDGTLCGFRSTSCPDQIAKNLKKALEEMN"
     CDS             5146..7107
                     /locus_tag="ctg10_13"
                     /transl_table=11
                     /translation="MILRCALCHNLYAIPANKGGCKKSIHRAGFVCCSGSLCGVYYCHR
                     EQHDEGCETKIWKQGGFFMYYSSGNYEAFAHPKKPEGVDHKSAYIIGSGLAALTAACYL
                     VRDGQMKGEHVHVFEKNALAGGACDGYKYDIGYVMRGGREMDNHFEVMWDMLHSIPSLE
                     TEGASVLDEYYWLNKEDPNFSLCRATVNRGEDAHTDGKFGLSDKGAMEIMKLFFTPDEQ
                     LQDKKITDFFDDEVLNTNFWMYWRTMFAFENWHSALEMKLYLKRYIHHIGGLPDFTALR
                     FTRYNQYESIILPMVRYLEGFGVQFHYNTKVTDVKFDIQKGRKLASSVTVEHAGETTNI
                     DLTENDLLFITNGGCVESCTVGAQDKATGFDPTIQPGNGWDLWKKIAAQDPSFGHPEKF
                     CSEPELSNWESATITTLDDKIPQYIRKICKRDPFSGHTVTGGIVTVKDSSWLLSWTLNR
                     QQQFKDQPKNQLCVWVYGLFSDKPGDYVKKPMRDCTGREICMEWLYHIGVPEDQIAELA
                     EHSANTVPVMMPYIDAFFMPRAMGDRPDVVPEGAVNFAFLGQFAETARDTIFTTEYSMR
                     TGMEAVYTLLNIDRGVPEVWGSTYDVRALIDATVKLRDGKKITDMDLPLIPRLALKEAL
                     KKIEGTDLEKFLKEYNAI"
     CDS             7462..9156
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283:2`,3`-cyclic-nucleotide 2`-phosphodiesterase
                     (Score: 254.2; E-value: 4.8e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_14"
                     /transl_table=11
                     /translation="MAIGAPAASACWFGDKSDVTILYTNDVHTYIDKQSPKLTYAAIAD
                     LKQSYQNAGKDVLLVDAGDHVQGTAYGSMDEGASIIKLMNAAGYDVATPGNHEFDYGMD
                     RAKAIMKEADFPYLSCNWVDLRTTLRVLPSVKVFVRGGRRIAFVGVTTPETFTKSTPAY
                     FMDKAQRKYIYDIQGGEDGKKLYDAVQKAIDKAKLLADVVIGLGHLGVDPSSSPWTSEE
                     VIAHTSGFDAFIDGHSHTVMENKQVQDASGKAVTLTQTGSYFANVGEMTIAADGTITTK
                     LIPTHEGMDAGIAAMQTGWVNTVDDMLGEKIAVGDSDFYVSDPATGKRRIRSAETNLGD
                     FVADGIYTYFNEVEKLHCDVAIMNGGGIRADVPAGDWTFKTCKQVSPFGNVACLMSVTG
                     KQIQDALEFAARFAGEDGKENGGFLQVAGATYEIHTDIPNTVQTDEKNVWIGSATGTPR
                     VQNVKIYDKVSGSYLPLDPGATYALAGMNYTLRNLGDGFAMFDGAELIKDYVSEDYLVM
                     STYAMIFDGADAAGLPHLSSANSPLAAYPGYLLNYEQPYGAGRITIL"
     CDS             9593..9880
                     /locus_tag="ctg10_15"
                     /transl_table=11
                     /translation="MPERTTQNAQTLLSPRIPRDTEHERYHPELEEELKECLFCLKRNE
                     MMFDMEVDTDLIEQRIYERQALLCRYRYLLARARELGLHTVLTRYQPMGR"
     CDS             10001..10147
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_16"
                     /sec_met_domain="TIGR03973 (E-value: 2.6e-26, bitscore:
                     82.1, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.5e-25, bitscore: 79.7,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERIKTIATRDLTKSVKTGGCGECQTSCQSACKTSCGVANQQCEN
                     SNK"
     CDS             10215..11666
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_17"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 8.5e-31,
                     bitscore: 97.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.4e-15, bitscore: 48.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.1e-16, bitscore: 52.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.3e-20, bitscore:
                     63.6, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHQYQLNGYNIVLDTCSGSVHVVDEVAYDVIAMYPEHTADEIVA
                     AMLAKYGSRPDVTEEDLRQCIDDVTSLKENGKLWSPDVYKDMAFDFKNRNTVVKALCLH
                     VAHSCNLSCSYCFASQGRYHGDRALMSFEVGKRAMDFLIENSGTRRNLEVDFFGGEPLM
                     NFDMVKKLVAYCREQEKIHNKNFRFTMTTNGVLIDDDVIDFCNKECHNVVLSLDGRKEV
                     NDRFRVDCAGNGSYDRIVPKFQEFVKKRGDKNYYMRGTYTHFNTDFTNDIFHMADLGFT
                     ELSMEPVVCDPSDPSALTEADLPILKEQYEILAKEMIKRDREGRGFTFYHYMIDLTGGP
                     CIYKRISGCGSGTEYMAVTPWGDLYPCHQFVGDPKYLLGDIWKGVTNTAVRDEFKHCNA
                     YARKECQDCWAKLYCSGGCAANSYHATGSITGVYEYGCELFKKRMECAIMIKVAENQEL
                     AAKGIEVPIELGSTCNACADGEACE"
     CDS             11663..13081
                     /locus_tag="ctg10_18"
                     /transl_table=11
                     /translation="MSMTTPIVDFVRSYAQSGTARLHMPGHKGQSLLGFEPLDITEICG
                     ADELYAPEGIIAESEANATRLFGTAHSYYSTEGSSQCIRAMLFLALQGAPQSGRRPVLL
                     AARNAHKALLYAAALLDFDIRWLWPSAQAEGALCSCPVTAEALTGALHALAQQGNTPFG
                     VYVTSPDYLGGVQDIPALAAVCRAQGVPLLVDNAHGAYLRFLPQNCHPIAQGAAMCCDS
                     AHKTLPVVTGGAYLHLAHDAPVQDEAAVRGALALFGSTSPSYLILQSLDACNAVLAGNY
                     SRRLVQCCAALEGLRRSLNKAAAARQCPVPLAVAGAQQEPMKLTLDAAALGCTGTALAD
                     ALRRAQLECEYADPRYVVLMFTPENPPQDFERLQTVLEQLLAAVPAGLPRPENRAGEFA
                     ALQQQAVQRCTIRQAVLGAQVRVPVHKALGRVCATPTVSCPPAIPVAVSGEEITPAAIA
                     LMQRYGIEELSVLR"
     CDS             complement(13143..13820)
                     /locus_tag="ctg10_19"
                     /transl_table=11
                     /translation="MTDLPFVSALVQADLPVWEQCLQTEFLQKMENGTLSEDCFKSYLV
                     EDSLYLREYAKIFAWGMTKATTMAAMRTYYSLLSFVQENEDLTRLRYLEQYGLREADIQ
                     SLPLRPESRAYLDCMIDAARTGEGEAECLMACLPCMLSYGWLFQKLLQRSPAVKDTYYG
                     ALVLDYAGSGYDAACRAWAERAEVACTGLSPERAARCSAIFRACSEHELHFWEMCATPR
                     TDI"
     CDS             complement(13813..14613)
                     /locus_tag="ctg10_20"
                     /transl_table=11
                     /translation="MKTALTIAGSDSSGGAGIQADIKTMTANGVFAMSAITALTAQNTT
                     GVTAIFDTTPQFLAQQLDAVFTDIYPDAVKIGMVSSAPLIDTIAERLHFYGAKHIVVDP
                     VMVATSGAKLLQDDAVQALTEKLLPLAEVLTPNIPEAEILSGMHIANAADMEAAARTIS
                     ERYGCAVLCKGGHQINDADDLLWRNGTGKWFKGKRIANPNTHGTGCTLSSAIASNLAKG
                     YDLDTAVERAKAYISGCLSAMLDLGHGSGPMDHTFNLKGDFVRD"
     CDS             complement(14836..15732)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 98.3; E-value: 5.9e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_21"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2e-17, bitscore:
                     53.8, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFEKLVAIEPVSLISSAEEELHRYAKEVVLYRDVPASDDEMVRRI
                     GDADAVLLSYTSRMGKEVIAQCPNIRYIGMCCSLYSEESANVDIAYARTRGIQVLGIRD
                     YGDRGVVEYVLHELTGLLHGFGMPMLRDEPVEITGLKVGIVGLGVSGRMIADALQFMGA
                     EISYFARSAKPDAEAAGMTFKPLPQLLADSEVVFTCLNKNVLLLGENEFAQLGAGKVLF
                     NTSIGPGFDSAALEKWLDLPGTHFFCDTRAAAGPVAEDFFSRENVRCANVSAGRTKQAF
                     VLLSKKVLDNIRTALGE"
     CDS             complement(15751..16551)
                     /locus_tag="ctg10_22"
                     /transl_table=11
                     /translation="MKTKLGIVGCGFLGNIVADAWKKGLLPDYELVGVTSRTRASAEKT
                     AANVGCAVCEDVDALLALEPEYIVEAASVESVRAMAIPVLKRGVNLVILSIGAFADLDF
                     YAQVKAAAVEGGAKVHLASGAIGGFDVLQTVTLMAQAQGLPETAGIETHTGAKGFRNTP
                     VWAEHLLTDTEKTTVFTGNAKQAIATFPRRVNVAVATSLATTGPEITGVTMHSVPGWVG
                     DDHCITAEIEGVKAVVDICSSTSAIAGWSAVSLLRNLASPVCFY"
     CDS             17168..18682
                     /locus_tag="ctg10_23"
                     /transl_table=11
                     /translation="MAYFYEEPSRTFGEYLLVPGYSSAENVPTAVSLKTPLVKYRKGQE
                     ECPLQMNIPMISAIMQSVSGDKLAIALARQGGVSFIYGSQSIENEAAMVRRVKSFKAGY
                     VVSDSNLAPTATLHDVLELKARTGHSTIAITADGTPNGKLLGIVASRDYRINHTPDDAC
                     VTTFMTPVEKLVTAPANTSLHDCNNIIWDNKINTLPLVDAEGNLVYMVFRKDYDSHKAN
                     VNELLDKNKSYVVGAGINTRDYAQRVPALVEAGVDVLCIDSSEGYSEWQSRTIGWIREH
                     YGDTVKVGAGNVVDAEGFRFLAEAGADFVKIGIGGGSICITRETKGIGRGQATAVIEVA
                     KARDEYYKETGIYVPICSDGGIVHDYHITLALAMGADFVMLGRYFARFDESPTNKVRIN
                     GQYMKEYWGEGSNRARNWQRYDLGGSTKLSFEEGVDSYVPYAGPLADGVQTTLYKVKST
                     MCNCGALSIPELQQKAKLTVVSSTSIVEGGSHDVVLKNATPSIMNG"
     CDS             18906..20423
                     /locus_tag="ctg10_24"
                     /transl_table=11
                     /translation="MNEIKVEPYIPDEDYDNPAMVVDFYEFTMANCLFLHGFKDTTLVF
                     DMFFRKNPDNQGYSISAGQRKLTRFLLDYHFNEQDIHWLRTKGMSEEFCEYLRTYKWKG
                     DMYALPEGTVCYPHVQMVRIECDLVGAILIETYLLQTMNFHSLIATKATRVTGLNTHTP
                     RNVMEFGTRRAQGESAGNDGAYAAVLGGCIGTANCLAEMKFGAEVKAVGTVAHSFIEFF
                     PTEFDAFKAFADTYPDSVSLLLDTYNIMESGLPNLIKLDDYLIEKYPNDPNRRVKSARI
                     DSGDLARGSKRLRKALDAAGKPYIKLVASNGLDEKKIANMELYEHAHFDSYGVGENLIT
                     SASDPVFGGVYKLVAVKKPDGSYTPKMKCSDSASKAIIPGKKMPWRLYDENGQAQCDLI
                     AMDGEVIEAGKPVTMVNLDSDAIERTITFTPTAVRPLLVPHILGGELAIDLPSIAEKKA
                     YIAKQLTEETWESELRLECPHKHYVNMTPAVAECRSRMYAELHGGKV"
ORIGIN
        1 ctgtgccgct gatgctgggc agcctgttcc agcagttcta caatctggcc gataccatca
       61 tcgtggggcg gttcgtgggc gtggaagcgc tggcggcagt aggcagcgtg ggcggtttga
      121 actatctggt gctgggcttt gtcaacggca ttgcctgcgg cttttccatc cccatctcat
      181 ggaccttcgg cgcccacgat caccacgaga tgcgccgcta caccgccaat accgtgtggc
      241 tgtccatcgc ctttgccacg gtgcttacca tcgttacggt ggctatgacc cggctggtgc
      301 tggtgtggac gaacaccccg gccgatatca tcgaccttgc ggatgtgtat atccgcacca
      361 tctttgcggg catccccttc accctgcttt ataatgtgac cagcgctctg atgcgtgcac
      421 tgggcgacag caagcgcccg ctgtattttc tgctggtggc cagcgtgctg aacatcgggc
      481 tggaccttgc ctgcatcatt gtgctcaaca tgggcgtgtt cggcgcagcc tttgccaccg
      541 tgttcagtca ggctgtggcg ggcatcggca gccttattta catcatgcgc cactacccgg
      601 aactgcgctg gaataaggaa gaagggcgca tcagcgctcc gcactgcgca aagctttgcg
      661 ccatgggcct ccccatgggc ctgcagtgca gcattaccgc cattggcagc gtggtgctgc
      721 agggcgcggt gaacggtctg ggcagcgata tcgtggcagc gcagaccgcc ggcggcaagg
      781 ctgcgcagtt cctctgcgtg ccgctggaga gcatcggcac cgccatgacc acctacacca
      841 gccagaatat gggcgcaaag gatctgggcc gcgtgaaccg cggcgtgaac accgcactgg
      901 gcatcggctg cgtgtacagc gtggcctcct tcctcatcct gcgcgtgctg gacaagcccc
      961 tgatcggcct gtttttggac gcaggcgaga ccgccattat ggccaatgcg caggacttca
     1021 tcttctggaa cagtgtgttc tacatcccgc tggcagtgct tatcatctac cgctacacca
     1081 ttcagggtct agggcactcc ggccttgcca tgtttgctgg tgtggctgaa atgatcgccc
     1141 gcgccatggt gggcttctgg ttcgtgccgc tgtggggcta ctttgccgcc tgcatcgcaa
     1201 gcccggtggc atggttcttt gcctgcttct tcctgatccc ggcgtatttt gtggtgttcc
     1261 gtaaactgca aaaggaaaag cagcaggaag ccgccgcaaa ggcgcagtaa gggttcataa
     1321 aaaatgcttt ttcttttcgc tttttcatgc tataataaca aataaatacg gctttgccgt
     1381 aacagggcag gggttataag tctttgaaaa gctggtttgc ttaaaggctt cccccggtcg
     1441 ggggaagcct aagaggacgg ctgttttcgg gatgaatggc tgcactgtcg gggcaatgcc
     1501 cgcaattgcg gcgggcggga aaatacaaaa agagaggcga atcgagatgt tggatatgat
     1561 caaatgcagc accggcggtg cgtactatgc gcgcggagag tgggtgcccg cagacggcaa
     1621 cgcacctgca gcgctggcag caaagggctt tgatgccgct gccgttgcca cggctaagac
     1681 cggtactatg gcctacaata ttatgcaggc acacaacacc agcggcgatg ccgagaacct
     1741 gaagatcaag tttgatgcca tggcaagcca tgacatcacc tttgtgggca ttatccagac
     1801 cgcccgtgct tccgggctgg aaaagttccc catcccttat gtgcttacca actgccacaa
     1861 cagcctgtgc gctgtgggcg gcaccatcaa cgaggacgac caccgcttcg gtctgtccgc
     1921 tgccaaaaag tacggcggca tctttgtgcc cccgcacatg gcagtcatcc accagtatat
     1981 gcgcgagcgc tttgcgggct gcggcaaaat gatccttggc tcggactccc acacccgcta
     2041 cggcgcactg ggcaccatgg ccatcggtga gggcggcggc gagctggcaa agcagctgct
     2101 gggccgcacc tatgacgttg cccgcccggg cgtggtggct atctacctga ccggcagtct
     2161 gccggcgggc tgcggccccc acgatgtagc cattgctctt gtgggcaagc tgttcaagag
     2221 cggctacgtc aaaaacaagg tcatggagtt cgtgggcccc ggcattgcct ccctgcggca
     2281 ggatacccgc aacgccattg atgccatgac caccgagacc acctgtctgt cttccatctg
     2341 ggagaccgac gaagtcaccc agcgttttct ggcagtgcac ggccgtgcag cagactataa
     2401 aaagctggca ccggcagacc ttgcctatta cgatggcgtg gtggaggtgg atctttctgc
     2461 catccgtccc atgatcgccc tgcctatgca cccctccaac gcctttacca tcgaggagct
     2521 gaacgcaaat ctggaggaca tcctccacgc ctgtgagcag gatgtgcaga agctgatcgg
     2581 ccgcaaggac gtgcagctgg atctgtgcag caagatcgag aacggcaagc tgcgggtaga
     2641 tcagggcgtt attgcaggct gcgcaggcgg tctgtacgac agcatctacg aggctgcttc
     2701 catcctcaag ggtcataccg gcggctgcgg cgactacgcc ctgagcgttt accccggcag
     2761 ccagcccatc atgatggaac tggtgcgcac cggcgtcatc ggcgagctga tggccagcgg
     2821 tgctaccatc cgcaccgcct tctgcggccc ctgcttcggc gcaggcgatg tgcccgccaa
     2881 cggcgctctg tccatccgtc acaccacccg caacttcccc agccgcgaag gctccaagcc
     2941 cggcagcggt cagctggcgg gtgtggcact gatggatgcc cgcagcattg cagccaccac
     3001 cgcaaacggc ggcatcctga cccccgccac cgacattgat tacgatccta ccgtgccgga
     3061 gtaccagtac gatgcttcca gctacgacac ccgcgtgtat cagggcttcg gcaagggcga
     3121 ttacgatgcc ctgctcaagt ttggccccaa catcaaggac tggccggaga tcgcaccgct
     3181 gggcgacaac ctgctgctga aggtggcttc ttatatcacc gaccccgtca ccaccaccga
     3241 cgagctgatc ccctccggtg agacctcttc ttaccgttcc aaccccttgg gtctggccga
     3301 gttcaccctc agccgcaagg acccggagta tgtgggccgc gccaaggctg tgcaggctga
     3361 ggagaatgcc cgccgcgccg gtgcagggga cgctgccctg ctggcaaagg tgaacgccgt
     3421 gcccggctgc gaacagctga gctggaacga tatccagatc gcctccacca tctttgcagt
     3481 caagcccggc gacggctctg cccgcgagca ggccgccagc tgccagcgtg tgctgggtgc
     3541 cggtgccaat atcgttactg agtacgccac caagcgttac cgctccaacc tgatcaactg
     3601 gggcatgctg cctctgcagc tggcaggtgc cacccccttt ggtctggggg actatgtgct
     3661 catccccaat gtgcgggagg cgctcaaggg cgacctgcag aacatcaagg cctacgttct
     3721 gggcgatacc gtcaaggagt ttgagctgta catggctccg ctcaccaccg atgagcgcca
     3781 gatcctggct gatggctgcc tgatcaattt ctataagcac taaggaagta acccgctatg
     3841 tcctgtgacc tgcatatcca ttccacctgc tcggatggtg ctgtgcccat cgagcggctg
     3901 gcacccatcg ctgcccgcac cgggctgcat gccatcgccc tttcggacca cgacaccctg
     3961 ctcagcgccc agtacgccta tgcccacacc gggcaggatg gggtagagct gatccccgcc
     4021 gtggagctga ctggctacga ctttgagcgc cagcaccggg tgcacctgct gtgctactac
     4081 ccggacgtgg actgcccggc gctacgcgag cattgcgcca tcatgaagga gcgccgcaac
     4141 gcctgcgctt tgcagagcgc aaaggagctg gagcagctgt acccgcagtt taccaccgac
     4201 cttgcatggg agaccacaaa ggccagcggg gtgctgttca aaagcgggct gatgcaggca
     4261 ctggaactgc tgggtctgac cgatggcagc atctacggcg agacctacca caagctgttc
     4321 gggtggaacc cccggggcat cgtgctgcac tcgccggagt atctgccggt gcggcaggtg
     4381 ctggctactg ccaaggcaag cggcggtgcg gtggtgtttg cccaccccac ggtgtataaa
     4441 agtatgcccc tgctgcgcga gctggcggca gagggcgcag tggacggcat agaggtgtac
     4501 caccccagca acagcccgga ggacagcgcc gagtgccttg cactgtgcaa gcagtacggc
     4561 cttgtggcta ctgcgggcac ggacttccat ggccgcaacc acaagcaccc gcaccccatc
     4621 ggcacctgta ccgcaccgga cgaggctgca gcgcagctgc gcgccatcgc cgaaaaacgt
     4681 aaaagagaga ggacgtaaag actatgagca aggaattttc cttcccgaac aagggcacct
     4741 gctccaagca gaccaacttt gtgctgaacg atgaccacac cattgcatcc atcgaggtca
     4801 tcggcggctg caacggcaac ctgaagggca tctgccagct gcttaccggc atgaaggcag
     4861 aggatgccat tgcccgtctg gacggcacgc tgtgcggctt ccgcagcacc agctgcccgg
     4921 accagatcgc caagaacctg aaaaaggctc tggaagagat gaactaaaat ccaccggaga
     4981 gccgctgcac agaaccttgt gcggcggctc tctttttgcg cagggacgat tttgaatgcc
     5041 cgccgctatg ctctgggcat gaatagcgga aaattatttt aaattagtgc aatgccgggc
     5101 agcccgcagg ctgcccggca ttgcactttt gagggagtgt tttaaatgat tttgcgctgc
     5161 gctttatgtc acaatttgta cgcaattcca gcaaataagg gcggatgtaa aaaatctata
     5221 caccgggcgg ggtttgtttg ttgttccggt tcactttgcg gggtatacta ttgccataga
     5281 gagcagcacg atgaaggctg tgaaacgaaa atatggaagc agggaggctt ttttatgtac
     5341 tattccagtg gcaactacga agcttttgca caccccaaaa agccggaggg cgtggatcat
     5401 aaatccgctt atatcatcgg ctccggtctg gcagccctga ccgctgcctg ctatctggtg
     5461 cgtgacggtc agatgaaggg cgagcacgtc catgtgtttg aaaagaacgc actggccggc
     5521 ggtgcctgcg atggctacaa gtacgatatc ggctatgtga tgcgcggcgg ccgcgagatg
     5581 gacaaccact tcgaagttat gtgggatatg ctgcactcca tcccgtctct ggagaccgag
     5641 ggtgccagcg tgctggacga gtactactgg ctgaacaagg aggaccccaa cttctccctg
     5701 tgccgtgcca ccgtcaaccg cggcgaggat gctcacaccg atggcaaatt cggcctgtcc
     5761 gataagggcg ccatggagat catgaagctg ttctttaccc cggacgagca gctgcaggat
     5821 aaaaagatca ccgatttctt tgatgacgag gtgctcaaca ccaacttctg gatgtactgg
     5881 cgcaccatgt tcgccttcga gaactggcac agcgctctgg agatgaagct gtacctcaag
     5941 cgctatatcc accacatcgg cggtctgccg gactttaccg ccctgcgctt tacccgctat
     6001 aatcagtacg aatccatcat cctgcccatg gtgcgctatc tggaaggttt cggcgtgcag
     6061 ttccactaca acaccaaggt caccgatgtg aagttcgata tccagaaagg ccgcaagctg
     6121 gcaagttctg tcaccgtgga gcacgcgggc gagaccacca acattgatct gaccgagaac
     6181 gatctgctgt tcatcaccaa cggcggctgc gtggaaagct gcaccgtggg tgcgcaggat
     6241 aaggccaccg gctttgaccc caccatccag cccggcaacg gctgggatct gtggaagaag
     6301 atcgccgcac aggacccctc cttcggtcac ccggaaaagt tctgctccga gccggaactg
     6361 agcaactggg agagcgccac catcaccacg ctggacgaca agatccctca gtatatccgc
     6421 aagatctgca agcgcgaccc cttcagcggc cacactgtca ccggcggcat cgttaccgtc
     6481 aaggactcca gctggctgct cagctggacg ctgaaccgtc agcagcagtt caaggaccag
     6541 cccaagaacc agctgtgcgt ctgggtgtac ggcctgttca gcgataagcc cggcgattac
     6601 gtcaagaagc ccatgcgcga ctgcaccggc cgcgagatct gcatggagtg gctgtaccac
     6661 atcggtgtgc ccgaggatca gatcgcggag ctggcagagc acagcgccaa caccgtgcct
     6721 gtgatgatgc cctatatcga cgccttcttc atgccccgtg ccatgggcga ccgccccgat
     6781 gttgtgcccg agggtgctgt gaactttgct ttcctcggtc agtttgccga gaccgcccgc
     6841 gacaccatct ttaccaccga gtactccatg cgcaccggta tggaggccgt gtacaccctg
     6901 ctgaacattg accgcggcgt gcccgaggtc tggggcagca cctacgatgt gcgcgctttg
     6961 atcgatgcca ccgtgaagct gcgcgacggc aagaagatca ccgacatgga tctgccgctg
     7021 atcccgcgtc tggctctgaa ggaagccctg aagaagatcg agggcaccga ccttgagaag
     7081 ttcctcaagg agtataacgc catctgatat ttcctctcct ccgatagacc cggcaacggg
     7141 tctgaatccc ccctaaaaaa gacctctccg ctgctctgcg acagggcgcg gggaggtctt
     7201 ttttgtatag gatttgtgta aaaatggtac aatgtgtgtc aaaataaagc gggacgtgaa
     7261 aattatttgt gccaaaagaa cgattttggc ttgtctgcgg cggcgttctg tgctatgcta
     7321 gagctattga aagggcagga gggaagagcc tgccccaaat gcgatacgcc aaaaataaaa
     7381 ggaggtcgtt ttcctgtgaa acaacttatt tcccgtcgca gctttttaaa ggctgctggt
     7441 gtgaccgctg ccgctgcatc catggccatc ggtgcgcctg ccgcatcggc ctgctggttt
     7501 ggtgataagt ctgacgtcac catcctgtac accaacgatg tccataccta catcgacaag
     7561 cagagcccca agctgaccta cgccgccatt gccgacctga agcagagcta tcagaacgcc
     7621 ggtaaggacg tgctgctggt ggacgcaggc gaccatgtgc agggcaccgc ctacggctcc
     7681 atggacgagg gtgcctccat catcaaactg atgaacgctg ccggttacga tgtcgccacc
     7741 cccggcaacc acgagtttga ctacggcatg gaccgcgcca aggccatcat gaaggaagcc
     7801 gatttcccgt acctgtcctg caactgggta gacctgcgca ctacgctgcg tgtgctgccc
     7861 tccgtcaagg tgttcgtgcg cggcggcaga cgcatcgcct ttgtgggcgt gaccaccccc
     7921 gagaccttta ccaagtccac cccggcctac tttatggata aggcacagcg caagtacatc
     7981 tacgatattc agggtggcga ggacggcaaa aagctctatg acgccgtgca gaaggccatt
     8041 gataaggcaa agcttctggc agatgtggtc atcggtctgg gccatctggg cgtagacccc
     8101 tcttcctctc cgtggaccag tgaggaagtc attgcccaca ccagcggctt tgacgccttt
     8161 atcgacggtc actcccatac cgtaatggag aacaagcagg tgcaggatgc ttccggcaag
     8221 gctgtcaccc tgacccagac cggctcttac tttgccaacg ttggcgagat gaccatcgct
     8281 gcggacggca ccatcaccac caaactcatc cccacccacg aaggcatgga cgcaggcatc
     8341 gccgccatgc agactggctg ggtgaacacc gtggacgata tgctgggcga gaagatcgct
     8401 gtgggcgaca gcgatttcta cgtctctgac cccgccaccg gcaagcgccg catccgctct
     8461 gccgagacca acctcggcga ctttgtggcc gacggcatct acacctactt caacgaggtg
     8521 gaaaagctgc actgtgatgt ggccatcatg aacggcggcg gcatccgcgc cgacgtgccc
     8581 gcaggcgact ggaccttcaa gacctgcaag caggtcagcc cctttggcaa cgtggcctgc
     8641 ctgatgtcgg tcaccggcaa gcagatccag gacgcattgg agtttgcagc ccgctttgca
     8701 ggcgaggacg gcaaggagaa cggcggcttc ctgcaggtgg ccggtgctac ctacgagatc
     8761 cacaccgata tccccaacac tgtgcagacc gacgagaaga acgtctggat cggcagcgcc
     8821 accggtaccc cgcgtgtgca gaacgtgaag atctacgata aggtttccgg cagctatctg
     8881 ccgctggacc cgggcgctac ttacgcactg gccggcatga actacactct gcgtaatctg
     8941 ggcgatggct ttgccatgtt tgacggcgca gaactgatca aggactatgt gtccgaggat
     9001 tatctggtca tgtctaccta cgctatgatt tttgacggcg cagatgctgc gggtctgccg
     9061 cacctgtcca gcgccaacag cccgctggcc gcataccccg gctacctgct caactacgag
     9121 cagccctacg gcgcaggccg catcaccatt ctgtaaattt atatttcccg tgaaaaggcg
     9181 aacccggaaa gtcctgcgga ctttccgggt tcgctctatc tataatagtt tttccgcgcg
     9241 gaatcataca aatagaaaag ccacctgagc ttcctcagat ggctttgttc tggttgggga
     9301 tgagagaatc gaactcccac aagtagagtc agagtctacc gcactaccac tatgcaaatc
     9361 cccaatattc tgttgtgttt tgcgggttga gccgctcaac gtgtgctatt atacgggaaa
     9421 agcccggagt tgtcaagcat atttttgaaa aaagttgtac ttttttggaa aatgccgcag
     9481 cagcgccgga taatctatgc cggagcgctg ccacgcttcg gcaggttctg cgcaccgcac
     9541 cgcctatact ggaaggtaca aaaccttgca gaataccaga aggaggatgc ctatgccgga
     9601 acgaaccaca caaaatgccc agaccctgct ttcgccccgc atcccgcggg ataccgagca
     9661 cgagcgctac cacccggagc tggaggagga gctgaaggaa tgcctgttct gtttgaagcg
     9721 caacgagatg atgtttgaca tggaggtgga cacggacctg atcgagcagc gcatatacga
     9781 gcgtcaggcg ctgctgtgtc gttaccggta cttactggcg cgcgcccggg agctggggct
     9841 gcacacggtg cttacccgct accagcccat gggcagatga aaaggcttag cgaaaaaatc
     9901 ttgacaaaag ccgcgctgcg tgatatccta ttacaagata aaagcgtacc ggaactatgt
     9961 ccggcgcgat aaatttttga gagttagaga ggtttctatc atggagcgta ttaagactat
    10021 tgctactcgt gacctgacca agagcgttaa gaccggtggc tgcggcgagt gccagacttc
    10081 ctgccagtcc gcctgcaaga cctcctgcgg cgtggctaac cagcagtgcg agaacagcaa
    10141 caagtgattt ttgcaaacct tatgccgcct ttgccgggcg gcattttttt gtgtaatctg
    10201 gaatggagtg taaaatggta catcagtatc aattgaacgg ttataacatc gtgctggaca
    10261 cctgcagcgg ctcggtgcac gttgtggacg aggtggccta cgatgtcatc gccatgtacc
    10321 cggagcatac cgcagacgag atcgttgccg ccatgctggc aaagtacggc agccgcccgg
    10381 acgtgaccga ggaggatctg cgccagtgca tcgacgacgt gaccagcctg aaggaaaacg
    10441 gcaagctgtg gagcccggat gtctataagg acatggcctt cgactttaaa aaccgcaaca
    10501 ctgtggtaaa ggcgctgtgc ctgcacgttg cccatagctg caacctgagc tgctcttact
    10561 gctttgcctc gcaggggcgc taccacggcg accgcgccct gatgagcttt gaggtgggca
    10621 agcgcgccat ggacttcctc atcgagaaca gcggcacccg ccgcaatctg gaagtggact
    10681 tctttggcgg cgagccgctg atgaactttg atatggtcaa aaagctggtg gcctactgcc
    10741 gcgagcagga aaagatccat aacaagaact tccgctttac catgaccacc aacggtgtgc
    10801 tcattgatga cgacgttatc gacttctgca acaaggagtg ccacaacgta gtgctgagtc
    10861 tggatggccg caaggaggtc aacgaccgtt tccgcgtgga ctgtgcaggc aacggcagct
    10921 acgaccgcat cgtgcccaag ttccaggagt tcgtcaagaa acgcggcgac aagaactact
    10981 atatgcgcgg cacctatacc cactttaaca ccgacttcac caacgatatc ttccacatgg
    11041 cagacctcgg ctttaccgag ttgagcatgg agccggtggt ctgcgacccc agtgacccca
    11101 gcgccctgac tgaggccgac ctgcccatcc tgaaggagca gtacgagatc cttgccaagg
    11161 aaatgatcaa gcgcgaccgc gagggcagag gttttacctt ctaccactac atgatcgacc
    11221 tgaccggcgg cccctgcatc tataagcgca tctctggctg cggctccggc accgagtaca
    11281 tggctgttac cccctggggc gatctgtatc cctgccacca gttcgtgggc gaccccaagt
    11341 acctgctggg cgatatctgg aagggcgtta ccaacaccgc tgtgcgggat gagttcaagc
    11401 actgcaacgc ctacgcccgc aaggagtgtc aggactgctg ggcaaagctg tattgctccg
    11461 gcggctgcgc tgccaactcc taccatgcca ccggcagcat taccggcgtg tatgagtacg
    11521 gctgcgagct gttcaaaaag cgcatggagt gcgccatcat gatcaaggtt gccgagaatc
    11581 aggagctggc tgccaagggc attgaggtgc ccattgagct gggctctacc tgcaacgcct
    11641 gcgccgacgg cgaagcctgc gaatgagcat gaccaccccc atcgtggatt ttgtgcgcag
    11701 ctatgcacag tctggcaccg cccggctgca catgcccggc cacaaggggc agagcctctt
    11761 gggttttgag ccgctggata tcaccgagat ctgcggcgca gacgagcttt acgcgccgga
    11821 gggcatcatt gccgagagcg aagccaacgc cacccggctg tttggcacag cgcacagcta
    11881 ttacagcacc gagggctcgt ctcagtgcat ccgcgccatg ctgtttctgg cgctgcaggg
    11941 tgcaccgcaa agcggcaggc gcccggtgct gctggcagcc cgcaacgccc acaaggcgct
    12001 gctatatgcg gcggcactgc tggattttga catccgctgg ctctggccgt ctgcgcaggc
    12061 agagggcgca ctgtgcagct gccctgtcac agccgaagcg ctgaccgggg ctttgcacgc
    12121 gctggcgcag cagggtaaca ccccctttgg cgtgtacgtc accagcccgg attatctggg
    12181 cggggtgcag gacatcccgg cgctggcggc ggtctgccgg gcgcagggtg tgccgctgct
    12241 ggtggataac gcccacggcg cctacctgcg ctttctgccg cagaactgcc accccatcgc
    12301 gcagggcgcg gccatgtgct gcgactctgc ccacaagacc ctgccggtgg tcaccggcgg
    12361 tgcgtatctg catctggcgc acgatgcccc tgtgcaggac gaagcggctg tgcggggagc
    12421 gctggcgctg ttcggttcta ccagcccctc ttacctcatt ttgcaatcgc tggatgcctg
    12481 caatgcggtg ctggcaggga attattccag gcggctggtg cagtgctgcg cggcgctgga
    12541 aggtctgcgc cgcagcctga ataaggccgc agcggcgcgg cagtgcccgg tgccgctggc
    12601 agttgccggg gcacagcagg agccgatgaa gctcacgctg gatgccgctg cccttggctg
    12661 caccggcaca gcgctggcag atgctttgcg ccgcgcacag ctggagtgcg agtatgccga
    12721 cccccgttat gtggtgctga tgttcacccc ggagaacccg ccgcaggact ttgaacgcct
    12781 gcaaaccgtg ctggagcagc ttttagctgc cgtgcccgcc ggactgcccc gccccgagaa
    12841 ccgggcaggg gagtttgccg ccttgcagca gcaggcggtg cagcgctgca ccatccggca
    12901 ggcggtgttg ggcgcacagg tacgcgttcc ggtgcacaag gcactgggac gggtgtgcgc
    12961 cacgcccacg gtatcctgcc cgcccgccat ccctgtggcg gtcagcggtg aggagatcac
    13021 cccggcagca atcgccctga tgcagcgcta cggcatcgag gaactctcgg tgctgcgata
    13081 aagattttat aagaagagaa cccggaaggt ctgcggacct tccgggttct ctatatttat
    13141 tcttaaatat ccgtccgggg tgtggcgcac atctcccaga agtgcagctc atgctccgag
    13201 caggcgcgga agatcgcgct gcagcgggcg gcacgctccg gcgaaaggcc ggtgcaggcc
    13261 acctcggcgc gctctgccca tgcacggcag gcggcatcgt agccggaacc ggcgtagtcc
    13321 agcaccagcg cgccgtagta ggtgtccttt acggcggggg agcgctgcaa aagcttctgg
    13381 aatagccagc cgtaactcag catacagggc aggcaggcca tcaggcactc agcttccccc
    13441 tcgccggtac gggcagcatc gatcatgcag tccagatagg cgcggctttc cgggcgcagg
    13501 ggcagggact ggatatcggc ttcccgcaga ccgtactgtt ccagataccg cagtcgggtc
    13561 aggtcctcgt tctcctgcac gaaggacagc agggaataat aagtgcgcat ggccgccatg
    13621 gtggtggcct tggtcatgcc ccaagcaaag atcttagcgt actcccgcag atacaggctg
    13681 tcctctacga ggtagctttt aaagcagtcc tcgctcaggg tgccgttttc catcttttgc
    13741 agaaactcgg tctgcaaaca ctgctcccac acaggcaggt cggcctgcac cagcgccgag
    13801 acaaagggca ggtcagtcac ggacaaaatc tcccttcagg ttgaaggtat gatccatggg
    13861 cccggagccg tgccctaagt ccagcatggc agacagacag ccggaaatgt aggccttggc
    13921 gcgctccacg gcggtgtcaa ggtcataccc cttggccaga ttggaggcaa tggcgctgga
    13981 cagggtgcag ccggtgccgt gggtgttggg gtttgcaatg cgcttgccct tgaaccactt
    14041 gccggtgcca ttgcgccaca aaaggtcgtc agcatcgttg atctggtggc cgcccttgca
    14101 cagtacggcg cagccgtagc gctcgctgat ggtacgggca gcggcttcca tgtcggcggc
    14161 attggcaatg tgcatgccgg acaggatctc agcctccggg atgttggggg taagcacctc
    14221 agccagcggc agcagctttt cggtcagtgc ctgcacagca tcgtcctgca gcagctttgc
    14281 accggaggtg gccaccatca cagggtccac cacgatgtgc tttgcgccgt aaaagtgcag
    14341 ccgctcggca atggtgtcga tgagcggggc agaggatacc ataccgatct ttaccgcatc
    14401 cgggtagatg tcggtgaaca cggcatcgag ctgctgcgcc agaaactgcg gcgtggtgtc
    14461 aaaaatggcg gtcacaccgg tggtgttctg tgccgtcagg gcagtaatgg cgctcatggc
    14521 aaacacgccg ttggcggtca tggtcttgat atcggcctga attccggcgc cgccgctgga
    14581 atcactgccg gcaatggtca atgcagtttt catgggtaaa atgctccttt acagcaaaaa
    14641 tgcggatatg cccgcaaaga catatccgca gataaaagcg ctatctccct acgttggcat
    14701 gatccaaatc aggtcacagg tcagggcaat acagcccact ctcagcccgc ttgcacggac
    14761 tcccctttta tagtagaaag cataccacaa tcggggaaaa gatgcaagaa aaacaggctg
    14821 cgcaaaatgc accgcttatt cgcccagtgc ggtgcggatg ttgtccagca cctttttgct
    14881 cagcagcaca aaagcctgct tggtgcggcc tgcggacaca ttggcgcagc gcacgttttc
    14941 ccgggaaaag aagtcctcgg ccacggggcc tgcggcggct cgggtgtcgc agaagaaatg
    15001 ggtgccgggc agatcaagcc acttttccag cgcagcggaa tcaaagccgg ggccgatgga
    15061 agtgttgaac agcaccttgc ctgcacccag ctgggcaaac tcattttcgc ccagcagcag
    15121 cacgttcttg ttcaggcagg tgaacaccac ctcgctgtcc gccagcagct ggggcagggg
    15181 cttgaaggtc ataccggcag cctcggcgtc cggctttgcg ctgcgggcaa agtagctgat
    15241 ctctgcgccc ataaattgca gcgcatcggc gatcatccgg ccggaaacgc ccagccccac
    15301 gatgcccacc tttagcccgg tgatctccac cggctcgtcc cgcagcatgg gcatcccaaa
    15361 gccgtgcaac agaccggtca gttcgtgcag aacatactcc acaacgccgc ggtcgccgta
    15421 gtcccggatg cccagcacct ggatgccccg ggtgcgtgcg taggcgatat ccacgttggc
    15481 gctctcctca gagtacaggc tgcagcacat gccgatatag cggatgttgg ggcactgcgc
    15541 aatgacctcc ttgcccatgc gggaggtgta gctcagcagc acggcatcgg cgtccccgat
    15601 gcggcgcacc atctcgtcgt cgctggcagg cacgtcacgg tacagcacca cctctttggc
    15661 gtagcggtgc agctcttcct cggcagagga aatcaggctg accggctcaa tggcaacaag
    15721 cttttcaaac atgacggact cctccttata ttagtagaag cagacgggcg aggccagatt
    15781 gcgcagcagg gagacggcgc tccagcccgc gatagcgctg gtggaagagc agatatccac
    15841 cacagccttc acgccctcga tctcggcagt gatgcagtgg tcatcgccca cccagccggg
    15901 cacggagtgc atggtcacgc cggtgatctc ggggccggtg gtggccagag aggtagctac
    15961 cgccacgttc acccggcggg ggaaggtagc aatggcctgc tttgcattgc cggtgaacac
    16021 ggtggtcttt tcggtgtcgg tcagcagatg ctctgcccac accggggtgt tgcggaagcc
    16081 ctttgcaccg gtatgggtct cgatgccggc agtctccggc aggccctgcg cctgtgccat
    16141 cagggtgacg gtctgcagca cgtcaaagcc gccgatggca ccgctggcca ggtgcacctt
    16201 ggcaccgccc tccacggcag ctgccttgac ctgtgcgtag aaatccaaat ctgcaaaggc
    16261 accgatggac agaatgacca gattgacgcc ccgtttcagc accgggatgg ccatggcgcg
    16321 caccgactcc accgaggcag cctccacaat gtactccggc tcaagcgcca gcagtgcgtc
    16381 cacgtcctca cagacggcgc agccgacatt ggcggcggtc ttttcagccg aggcgcgggt
    16441 gcggctggtc acgcccacca gctcgtagtc cggcagcaga cccttcttcc acgcgtcagc
    16501 tacgatgttg cccagaaatc cgcagcccac aatacccaat tttgttttca taccgtatcc
    16561 taaactcctt ttttctgcct gtggcagcat attcatagcc agtataccat accgggtaca
    16621 aaaagggaaa taatgtttgc ggcagcccgg cggggcaaga cataaaaagt taacaaaata
    16681 aattacaaat aaattacaaa accctattgc aaaatggttt caaaagagtt acaatatggt
    16741 tacagcaagg gcaaagcccc aaggctgtgt gtgaaatctt tttcttcttg tttttgggat
    16801 actgggcgcg ggtcctcctc ctccggctgt tctccttcac agctatgacc catgcgccgc
    16861 acaggcagtg tcccgcttcg tgtgcaaaag ggctcgtccg gtgttccgga cgagcttttt
    16921 tgcattctgc aagccctgtt ttgcccgtaa aagtgatact tcaaaaatca aagtatgacc
    16981 aatgcccgaa aacgcttggc aatttgtctg tttttccgca aaggacaatt ataaagtttg
    17041 gcgcggcagg ggtttgtatt cttgcgggct ttgtggtaaa gtatatacaa tcaatttata
    17101 agcagcaaac atgaatgatt ttgatgctga tttgtatcgg atgcgttaag agaaaaggag
    17161 tttgattatg gcttatttct acgaagaacc ctcccgcacc tttggcgagt acctgctggt
    17221 ccccggctat tcctctgcgg agaatgtgcc cacagcggtc agcctgaaga ccccgctggt
    17281 caagtaccgc aagggacagg aggagtgccc gctgcagatg aatatcccca tgatcagcgc
    17341 catcatgcag tcggtctccg gcgataagct ggccattgca ctggctcgtc agggcggcgt
    17401 ttcctttatc tatggctctc agagcattga gaacgaagcc gccatggtgc gccgtgtcaa
    17461 gagcttcaag gccggctatg tggtgtccga ttccaatctg gctcccactg ccaccctgca
    17521 tgatgtgctg gaactgaagg cacgcaccgg ccactccacc attgccatca ctgccgacgg
    17581 cactcctaac ggcaagctgc tgggcatcgt ggcctcccgc gattaccgca tcaaccacac
    17641 cccggacgac gcctgcgtta ccacttttat gacccccgtt gaaaagctgg tcaccgctcc
    17701 ggccaacacc tctctgcacg actgtaacaa catcatctgg gacaacaaga tcaacaccct
    17761 gccgctggtg gatgccgagg gcaatctggt gtatatggta ttccgcaagg actacgattc
    17821 ccacaaggca aacgtcaacg agctgctgga caagaacaag agctatgttg tgggtgccgg
    17881 tatcaatacc cgcgactacg cccagcgcgt gcccgcactg gtagaggccg gtgtggatgt
    17941 gctgtgcatc gactcctccg agggctactc cgagtggcag agccgcacca tcggctggat
    18001 ccgcgagcac tacggcgaca ccgtcaaggt gggtgccggc aacgtggtgg atgccgaggg
    18061 cttccgcttc ctcgcagagg ctggcgcaga cttcgtgaag atcggtatcg gcggtggctc
    18121 catctgcatc acccgcgaga ccaagggcat cggccgcggt caggctaccg ctgtcattga
    18181 ggtcgccaag gctcgtgacg agtactacaa ggagaccggc atctatgtgc ccatctgctc
    18241 cgacggcggc atcgtccacg actaccacat caccctcgcg ctggctatgg gcgcggactt
    18301 cgtcatgctg ggccgctact ttgcccgctt tgacgagagc cccacgaaca aggtgcgcat
    18361 caacggccag tatatgaagg agtactgggg cgaaggctcc aaccgtgccc gcaactggca
    18421 gcgctatgat ctgggcggtt ccaccaagct gagctttgag gagggcgtgg acagctatgt
    18481 gccctacgcc ggtcctctgg cagatggcgt gcagaccacc ctgtacaagg tgaagagcac
    18541 catgtgcaac tgcggcgctc tgtccatccc cgagctgcag cagaaggcca agctgaccgt
    18601 tgtttcttcc acctccatcg tggagggcgg cagccacgac gttgtgctga agaacgccac
    18661 ccccagcatc atgaacggct aagcctgttc tgaaaagaat ctattgattt aagcgcagag
    18721 accgctgcac agcgtttgtg tagcggtctt tttgcgcgaa aatacttgca ccggcagggg
    18781 aatcgtgcta tcatgataga aacgctctgt catgacaggg cggaggatcc ccctgccggg
    18841 caagcggcag gcggcgcgca gtagggaaga gctgacgccg ggtataaata gagaggaaaa
    18901 cattcatgaa cgagatcaag gttgagcctt atatccccga tgaggactac gataaccccg
    18961 cgatggtggt ggatttttac gaattcacca tggcaaactg cctgttcctg catggcttta
    19021 aggataccac gctggtgttt gatatgttct tccgcaaaaa cccggataat cagggctatt
    19081 ccatcagcgc aggccagcgc aagctgaccc gctttttgct ggactatcac ttcaatgagc
    19141 aggatatcca ctggctgcgc accaagggca tgagcgagga gttctgcgag tatctgcgca
    19201 cctacaagtg gaagggtgat atgtacgccc tgcccgaggg cacggtctgc tacccccatg
    19261 tgcagatggt gcgcatcgag tgcgatctgg taggcgcgat cctgatcgag acctatctgc
    19321 tgcagaccat gaacttccat agcctgatcg ccaccaaggc cacccgcgtc accggcctga
    19381 acacccacac cccccgcaac gtcatggagt tcggtacccg ccgcgcacag ggcgagagcg
    19441 ctggtaatga tggcgcttac gcagcagtgc tgggcggctg catcggtacg gccaactgtc
    19501 tggcagagat gaagttcggc gcagaggtca aggctgtggg caccgtggca cacagcttta
    19561 tcgagttttt ccccaccgag ttcgatgcct tcaaggcctt tgccgatacc tacccggatt
    19621 cggtcagcct gctgctggat acctataata ttatggaaag cggcctgccc aatctgatca
    19681 agctggacga ttatctcatt gagaaatacc ccaacgatcc caaccgccgc gtcaagagcg
    19741 cccgcatcga ctctggcgac cttgcccgcg gctccaagcg gctgcgcaag gcactggatg
    19801 ccgccggtaa gccctacatc aagctggtag cctccaacgg tctggatgag aagaagattg
    19861 ccaacatgga gctgtacgag cacgcacact tcgactccta cggcgtgggc gaaaacctca
    19921 tcacttctgc ctccgacccc gtgttcggcg gcgtatacaa gttggtggca gtgaagaagc
    19981 cggacggcag ctacaccccc aagatgaagt gctcggactc cgccagcaag gccatcatcc
    20041 cgggcaaaaa gatgccttgg cgtctgtacg acgaaaacgg tcaggcacag tgcgacctga
    20101 ttgccatgga cggcgaggtc atcgaggccg gtaagccggt cactatggtc aatctggact
    20161 cggacgccat cgaacgcacc attaccttta cccccaccgc tgtgcgcccg ctgttggtgc
    20221 cgcatattct gggcggcgag ctggccattg acctgccctc tattgcagaa aagaaggcct
    20281 atattgcaaa gcagctcacc gaggagactt gggagagcga gctgcgtctg gagtgccccc
    20341 acaagcacta cgtcaacatg acacccgcag tggccgagtg tcgttcccgg atgtacgccg
    20401 aactgcacgg cggcaaggtg taagcagcac cgaataagcg gtttttcttg acaaaacagg
    20461 gaaactattg tatcataaaa gccgctgatt taataaaaat gttaatacca ccagattgcg
    20521 aagaacagtg tggttgtaat aatttttcct cacacctgtt attcccggct ccctctcaag
    20581 ccagagggca gcagaacttt gtaagccggg tttgcgccgc tgtggtgaaa ttggcagaca
    20641 cgagggactt aaaatccctt tctggagaca gagtacgggt tcgacccccg tcggcggcat
    20701 gtaaaagctc agaattgttc gttgattcga atgattttga gctttttctt tttattccat
    20761 tttctgggag cgctgagcgg gcgagaggga tttttcgcga aaaaaggagg agtctctctc
    20821 gtgcgtaacc gtgatttaag acccgctgcc aaggcaaacc ccaccatcca acaggccttt
    20881 gaaaggttcc aaaagtacaa ccggctcaag aacctctccc aaggctcact cgacttctac
    20941 gccgcaaagg gcagaagctt ctttcggttt ctgggggata cagagcagcc cattcatacc
    21001 atcacagaag aaacggtgga ggactatatt ttctatatga aggaccagca gctccacgat
    21061 acgaccatca atacgaacct ccgtatggtg cgtgcgtttt tgtactggtg catggaaaag
    21121 ggctatctgg aaaagtatcc gatcagactg gtgcgtgccg atgatccaat caaagaaccc
    21181 tacaccaccg acgaattgca gaagctactg aaggaaccgg actgcaagac ctgctctttt
    21241 gccgaatacc gcaattgggt cattgtcaac ttcctgcttg gtaccggctg ccgtgcgtcc
    21301 acgctgctca acctgcacat tgaccctgtc tcgttgacgg aagaagaacg acagcaaaaa
    21361 ctgcaggaga ttctggattg tattaatgcc tctcgcaaaa agaaaaagga ggccgacgaa
    21421 cagcttgatc ccattgtgcc ggaggaagaa ccggaaaccg ccggggcaac tccacagcct
    21481 gcaaaacagt acatcacaga tcttgttggc gaggattaca agaactggca tgggatcgtg
    21541 gtgcttgatg cgggcacgaa ctccggtaaa acctatttta ttctgaagac attgctgcca
    21601 tggacatatg aacatcgtaa gcgtatcctg atcctgtgca atcgcgaagc tctgcgcaac
    21661 cagatc
//
