LOCUS       c00044_gnlPro..        15349 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HDDIGPKE_44.
ACCESSION   c00044_gnlPro..
VERSION     c00044_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 04:11:18
            Original ID  :: gnl|Prokka|HDDIGPKE_44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15349
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..387
                     /locus_tag="ctg44_1"
                     /transl_table=11
                     /translation="PREYQEAYRSLNECREIDYQVMSADNFTAEDIVSIYVLITADPVA
                     TAVVSEMIVELLKKITHEVLIRLKKAKEKQKTENSSETHVRLLTRETPLENGGVQIERE
                     VIVNKPLDNDHICELIDKLVKLDK"
     protocluster    1..15349
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5829:10069]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5830..10069
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..15349
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15349
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             405..1370
                     /locus_tag="ctg44_2"
                     /transl_table=11
                     /translation="MENAHDMRFIFYHKRNIDEGRDSVYTFVNMLEQAQIDVVDRAVLK
                     HSYEEEDFVDEEMLHLILETLDIHIPIQYTPRCRRTMNAEAYGPTEPGILIDELFEYTI
                     ISFLFTMYSLAYDQSEENTIRCMKNFYVIEDLQRRQHQFGTHNQEQLYRMSMLPENLIH
                     TAMDNYWTIWTFVVGHELYHLMNPEDQEGKKTEFRADRYAYQLLIKLIMKQKAGEIPEQ
                     LRVFYECQYLAPAILFEMFRLFDVYSELRGLEVNLSSHPAPIERQKNILELSDTDVPEE
                     METKDGNLLLNCILDSSEMAENWLRDKIRKGKLHPLDTLG"
     CDS             complement(2389..3006)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AstE_AspA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_3"
                     /sec_met_domain="AstE_AspA (E-value: 5.3e-08, bitscore:
                     22.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPFLGHGGRELVSRPVTAEKCNLPGDFVSHVRIMNTGCQTASLG
                     NLFGLPYVVMRKSEPIDTTTLNYNWQVWETNAFSVYTKETDEIDERSAQEAVAAVLRYL
                     SRVGLLRYNCHSGYLSSVVQETEMANVLTPAGGIFRRFVEPGQEVEYGQKLGVILGPFT
                     AEIEAEVLCPTSGVVFFALKKPLTTEHEVAFKVIRRLHGGCL"
     CDS             3251..4288
                     /locus_tag="ctg44_4"
                     /transl_table=11
                     /translation="MPYILLYLFLAVLCLLNIRFCPTGADIKKTMNRLHELRFIFAVLI
                     IFSHCTNPFSPMPHILLPLSKISTLGVGYFFISSGFGLACSVASKPNYLRNFWKKIVNL
                     LWITLFSSVVSTLIRNTMLGEHQIFQLVNWYMPTLIALYLVFYISYRIFPKNKFRRVAF
                     LSGVIFIITALLCAFDAVTGLNHRVYYISELAFPFGVFIYEYADILASFLKKKYALPLI
                     VAAELIFSFFGLTVPEKSLPDLIFHNLMIFPFGLLLIWLLDKFKVGNRIISAMNPYAPF
                     LYLFQFVVLDVMKNYYITNARPFGIFYFWGVLFFTCILAVALQHLYNFIGAEVHKHFCP
                     NRSTL"
     CDS             complement(4301..5680)
                     /locus_tag="ctg44_5"
                     /transl_table=11
                     /translation="VRTLSEIIVKRDYSRKTPSSVFYKDSPFWQRLICICYVGFIALAG
                     LGDWKTMQSILGGLPKIITAGVIGMAIVYGLIYPEMERVKKVFWPTLVYMSLIVLLFLW
                     SMVIWLMDFSAVSTMIRACSKLMFQSISILAAVSGVFLLGSKTIDLFAIAVCLANAGIM
                     VLEIPTFGLSASIQSLMRCLLTFGEAEGYARNLEIHDLTFVFGQLVLYYAAFAPHDTKQ
                     EKRRRWRMLVACTFFFFVGMKRIAIPAVVLFIFVTMIVRCFKDKKKLLILWGVAWVVFF
                     FLYIYAVRSGLVSKLLHITGIDMMGRDYLWSLANDYYDLSITYVGHGFEYVDTIVTEWY
                     NSGIINHPYPFHNDILKVFVEMGFPGFVFWAGIQYIITPIFWIHYADEDTALLYLSNLS
                     YMTMTYLTDNTSFSFWCTMTLRLLPLAYSVQRRKPPKPQVWKPKDKKEMQDRIRIMMQE
                     T"
     CDS             complement(5830..7041)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_6"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 8.1e-15,
                     bitscore: 44.9, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVRDSRPPFAGLANLSEEQLHRLPTPCYLLDEAQLRRNGEILLD
                     VQQRTGCRILLAQKAFSNFNVYPVLAPYLAGTEASGLYESRLGREELPEKENHVFCAAY
                     RADEFEELLQYADHIVFNSPSQLAKFGPAAKAVGKSIGLRINPECSTQEGHEIYDPCAP
                     GSRLGTTRAQWDAAVAAHPELPALLDGLHFHTLCEQDADALAVTLAAVEKKFADLLPRM
                     QWLNFGGGHHITRPGYALDTLESCILSVRQKYGVQVYLEPGEAWALNAGYLVTTVLDTL
                     RNGDTSLAILDMSAACHTPDVIEMPYRPPLLDAGEAGEKAHTVRLGGPTCLAGDIIGDY
                     SFDAPLAEGDKLIFGDMAIYTTCKNNTFNGMPLPPIWLLGADGNCRELVHFGYQDFKMR
                     LGAK"
     CDS             complement(7041..8300)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_7"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 3.9e-45, bitscore:
                     144.9, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.7e-33,
                     bitscore: 105.6, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVLIIGCGGVASVAIHKCCQVPEVFTEICIASRTKAKCDKLAA
                     ELAPTTATKITTAQVDADKVEEVIALIKAYQPDLVMNIALPYQDLTIMDACLACGVNYM
                     DTANYEPENTDDPEWRAIYEKRCKEAGFSAYFDYSWQWAYAKKFEEAGLTALLGSGFDP
                     GVTQAYCAYAKKHEFDTIDTIDILDCNGGDHGYAFATNFNPEINLREVSAPGSYWENGH
                     WVEIPAMSIKREYNFDQVGDKDMYLLHHEEIESLAKNIPEAKRIRFFMTFGQSYLDHMR
                     CLEDVGMLSTTPVNFNGQEIVPIQFLKALLPDPASLGPRTKGKTNIGCIFTGKKDGKDK
                     TYYIYNVCDHQECYKEVGSQAISYTTGVPAMCGALMLLTGKWTTKGVHTVEEFDPDPYL
                     DALDKYGLPRSESHNPALVD"
     CDS             complement(8337..9212)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_8"
                     /sec_met_domain="Arginase (E-value: 1.2e-77, bitscore:
                     250.9, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPNVETFIGCDSSYRAASIVLYGAPYDSTTSYRPGARFGPAAIR
                     HESYGLETYSPYQNADLTDFDVFDSGDLELCFGSSELALADIEARAEEILKDGKFPLLL
                     GGEHLVTLGAVRAAVKKYPDLHIVHFDAHADLRDDYLGAKLSHACVLRRCHELVGDGHI
                     HQFCIRSGDRAEFEFAAQHTEMHKFDFTGLAELTAQLCESKVPVYLTIDLDCLDPSCFP
                     GTGTPEAGGVSFLQLLDAIRTVTKANIIGADLNELAPTLDTTGVSTATACKVLRETLIA
                     LDKGWPGFQV"
     CDS             complement(9212..10069)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_9"
                     /sec_met_domain="Spermine_synth (E-value: 3.2e-54,
                     bitscore: 173.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 3.4e-23,
                     bitscore: 71.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFWFSEFHTPDVKHSIRVNKQLYSKQSDYQRIDIFETPEFGRVL
                     TLDGNVMLTERDEFIYDEMIVHVPMAVHKEAKDILVIGAGDGGVVRELTRYDRVERIDL
                     VEMDPQVVEACRAYLPGNACRMDDRRVHIYFENALKYIRRCEEEYDLIIVDSSDPFGPS
                     EGLFTREFYGSCFNALKEDGIMVNQQGSPFYAEDASAMQRSHKRIASTFPISRVYQAHI
                     PTFAAGYWLFGFASKKYHPIDDLDAEAWKALNMRTRYYTTKLHIGAFYLPAFLEEMLRE
                     VEEH"
     CDS             complement(10082..11548)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_10"
                     /sec_met_domain="OKR_DC_1_C (E-value: 4.7e-12, bitscore:
                     36.3, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 3.1e-123,
                     bitscore: 401.1, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNENKARSRLDQRRAPIYEALERFRQMRVVPFDVPGHKRGRGNPE
                     LTAFLGQQCVGVDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSSVQS
                     MVLTACKRGDEIILPRNVHRSVLNALVLCGAVPVYVNPEVDKRLGISLGMKREQVAKAI
                     KEHPNAVAVLVNNPTYYGICSDLRAIVKMAHDAGMLCLADEAHGTHFYFGGGLPVSAMA
                     AGADMASVSMHKSGGSLTQSSLLLIGPNVHPGYVRQIINLTQTTSGSYLLMSSLDISRR
                     NLALRGRQVFHQVADIAEYAREEINAVGGYYAFGKELCNGDSVFDFDTTKLSVHTLDIG
                     LAGIEVYDILRDEYDIQIEFGDIGNILAYLSIGDRPQEVERLVSALAEIKRRYRTDGSG
                     LLSQEYIDPVVAASPQEAFYAPKKSLPLRETEGMVCSEFVMCYPPGIPILAPGERITKE
                     ILNYIEYAKAKGCSMTGPEDPEILHLNVLA"
     CDS             12119..12862
                     /locus_tag="ctg44_11"
                     /transl_table=11
                     /translation="MEKEGIWMALPIAIVEDQTPDAQRLEELLQQQLPEAECTWFTCGD
                     DFLRAAAEPGLYAVVFLDICMAGTNGIETARRLRQADPEVLIVFVTSSPEYVWDAFPVH
                     PFDYLLKPYQEEKFEHLAAELRRALRCKEPELEIRIARQSIQLPLRKVLYAIARNHYVL
                     ITTEEGEYRAMCSFAQIEEKLTALENFMSCNRGVIINMDKVLRFGEDCIEILDGTRLPV
                     RQKDKCTLLARFTQYQFRHMRQELH"
     CDS             12880..14196
                     /locus_tag="ctg44_12"
                     /transl_table=11
                     /translation="MDLALFGRYFLDFALLYPSAFLCLAALWEKLRTPKRTACIAAGCI
                     TLLCFGCAALCAVFGLSSNSLLPAIVLVSFWLLRWRVTPEVTVSQTAFLFSISAVMMAV
                     CSLLSTVLNAQAEISNPRTVCLASTALLRLGLAAVLTVLFWFTAVQWGRWLLREYSGEA
                     FWQSAWPLPALYAVFLVYCMPLNPAVVLVGRLKIISVLAVSISLFGIFLLLYEMYRVAR
                     EFTRNARLDRENQLLAMESRRYMELQTYLDNTRRLRHDFRQHLHVIAGLTETGQLEELK
                     SYLHQYESELSEHRPSLCANAAVDALAGYYDHAAGQQGVPVEWKLALPRQLPMPEADLC
                     TILGNLLENALHASQKLPPEQRRVQVMAQMLSPAMLGLVVENRYDGMLKKQQGVLRSTK
                     HEGTGIGLVSAETVVHKYNGNLHLETEEHLFRVNVLLNL"
     CDS             complement(14281..14520)
                     /locus_tag="ctg44_13"
                     /transl_table=11
                     /translation="MGFFAVLAASLFAVFIFTVFGGYSLLLWCQQSLWMVVPPALVLAV
                     LVWTFLKMDDKITALQKRVDELEAAQKSTEKLEK"
     CDS             complement(14540..15016)
                     /locus_tag="ctg44_14"
                     /transl_table=11
                     /translation="MIYDTLNNLPNYLGVSDNLDTVIEYIMARDITTLPAGRTRIDGDK
                     AVVTVSTVTPQTSDKALFQRHDNHITLETDLDGSELFEVSLAELTPTKPTDEAADTTVG
                     TAGTSIAGMLCEGRFALYLAGEPYKSGLKAQGCGKLKKAVFSIELDPDEEETEE"
ORIGIN
        1 cctcgtgaat atcaagaggc atatcgttcc ttgaatgagt gtagagaaat tgattatcag
       61 gtgatgtctg cggataactt cacagctgaa gacattgtaa gcatttatgt tctgataaca
      121 gcagaccctg tagcgacagc agttgtgagt gaaatgatag ttgagcttct taaaaagatc
      181 acccatgaag tgctgattcg attgaagaaa gcaaaagaaa agcagaaaac agagaacagt
      241 tctgagacac atgtaaggct tttgacccgt gagacaccgc ttgaaaatgg aggagtccag
      301 attgagcggg aagtcattgt aaataaacca ctggataatg atcatatttg tgagctgatt
      361 gataaactgg taaagctcga taaataaaaa gaaggtattt tcacatggaa aatgcacatg
      421 atatgcgatt cattttctat cacaagcgga acattgatga gggaagagat agcgtatata
      481 cttttgtgaa tatgctggaa caggcgcaga ttgatgttgt agacagagct gtgttaaagc
      541 attcatacga agaagaagat ttcgtagatg aagaaatgct gcatttgatt cttgagacac
      601 ttgatattca cataccaatt cagtatacac cacggtgcag gaggacgatg aatgctgaag
      661 catatggacc aactgagccg ggaattttga ttgacgaatt gtttgagtat acgattattt
      721 cgtttctctt tacgatgtat tctcttgcat atgaccaaag cgaagaaaat acgatacgct
      781 gtatgaagaa tttttacgtg attgaagatc ttcagcggag acagcaccag tttggaacgc
      841 ataatcagga acaactttat cggatgtcga tgttaccaga aaatttgata cacacagcaa
      901 tggacaatta ctggacaatt tggacgtttg ttgtgggaca cgagttgtat catcttatga
      961 atccagagga tcaggaagga aaaaagaccg aatttcgtgc ggatcgatat gcgtaccagt
     1021 tacttattaa gcttatcatg aagcagaagg caggagaaat cccggaacaa ttaagggttt
     1081 tctatgaatg tcagtatttg gcaccagcta tcttgtttga aatgtttcgt ctgtttgatg
     1141 tatattcaga actgagaggt ttagaggtga acctatcaag ccatccagct ccaatagaac
     1201 ggcagaaaaa tattttggag ttgtcagaca cagatgttcc ggaggaaatg gaaacaaagg
     1261 atggaaactt gctgctgaac tgtattttgg acagtagtga aatggctgaa aactggctgc
     1321 gagataaaat tcgaaaagga aaactgcatc cattggatac acttggataa aacaagccga
     1381 aattttcaaa gttactgcag ctaacagaaa gtcttacacg gttgtgtcaa gggctgaaac
     1441 cgacagtgac acagaaacat tgtaaaacct ccgctgaaaa aatttttatt gagaaatgaa
     1501 aaaggcgcaa cttcgatttt gcaggtcgaa attgcgctat gtaattagaa atggaaaaat
     1561 attgccttgc tctagtgcca taaattgcac gaaacatctt gacagcaagt atatctgact
     1621 gtagaataca attcaataag tctttgctct ttgaaattgt ctttattgct ggttggattc
     1681 caaggtcaaa ttacactttt gtggaaataa aacgaatcaa cgccgaatat cgttcatcct
     1741 cgcacctttg tgtgggggtg cgtgagtgcg tggttcggga gagcgcttgc atggcatgca
     1801 agaggtcacc ggttcgatcc cggtaatctc caccagaagg aaaaagcact gcacagaaat
     1861 gtgtggtgct tttttgttgc tgccaaacga gtgagggttt agctcaccca ggagagcgcc
     1921 gtgcatggac tgcaagaggg tcaccgtgat cagaatcggc ccggtaatct ccaccagaac
     1981 gaaagcacta cacagaaacg tgtggtgctt ttttgtttta tctgccgttt accttaacga
     2041 cccctttcat gaaaaatgcg tttgtcgcac tccgcagaga gcgacaaacg caaaatataa
     2101 ataatctttc ctctgatcat agtcagagca caccggaaca tctacacaaa actttgcatc
     2161 aactccctca agcagctgca gccatgcatc gacgtcctcc attccgacgg aaacggcacc
     2221 gcgctgccgg agcagcctcc tgaagctgcg gagccggaga aaaaagagga cgagcttccc
     2281 atgaccgact gaacctgaaa aagatatggc ctggcagagt gcccacgggc acactgccag
     2341 tccatttttt acgagaaaaa cggttttagc aaagcatcca gcttctgttt acaggcagcc
     2401 gccgtgcagc cgccggatca ccttgaaggc cacctcgtgc tcggtcgtca gcggcttttt
     2461 gagggcaaag aacacaacgc cgctggtagg acagaggacc tccgcttcta tctctgcggt
     2521 gaatgggcca aggatgaccc ccagcttctg gccgtattcc acctcctgcc ccggctccac
     2581 aaatcggcgg aaaatgccgc ccgccggggt gagcacattg gccatttcgg tttcctgcac
     2641 aacagaggat agatatccgc tgtggcagtt atagcgcagc agacccaccc ggctgagata
     2701 ccgcagcacc gccgccacag cctcctgtgc gctgcgctcg tcgatttcat ccgtctcctt
     2761 ggtgtagacg ctgaaggcgt tcgtttccca gacctgccag ttgtagttca gagtggtcgt
     2821 gtcgatgggc tccgatttgc gcatgaccac atagggcagg ccgaacaaat tgcccagact
     2881 tgccgtctgg cagccggtat tcataatgcg cacatgagac acaaaatcgc cgggcagatt
     2941 gcatttttct gccgttacag gtcgagaaac aagctctcta ccgccgtgac ccaaaaaggg
     3001 tatcatatag caaagctgag cagctgtgaa aaagcagaag ctcagctttt ttgcattttc
     3061 ggttccgaaa atgctatgcc tattctgata tgtaccccca ataccaggtg tccagtaggg
     3121 ggtacatatc agtcaaaaaa gatgcagtag cccctttttg ttatccgctt gccatatcaa
     3181 acagcttatg ataagataaa tttgtgtacg ctttttagtc cacagaattc cgaacacaag
     3241 gaggccttgc atgccctata ttttactcta cctcttttta gcagtacttt gtcttttgaa
     3301 catccggttc tgtccaaccg gcgcagatat caaaaagacg atgaaccgtc tgcacgagtt
     3361 acgctttatt tttgcagtac tgatcatctt ttctcattgt acaaatccgt tttctcctat
     3421 gccacacatc ctgctgccgt taagcaagat ttccacactc ggtgtggggt atttctttat
     3481 ctcatccggc tttgggctgg cttgctccgt tgcatccaaa ccgaactatc tgcgcaactt
     3541 ttggaaaaaa attgtcaatc tgctatggat cactctgttt tcaagcgttg taagcacact
     3601 tattcggaac acgatgctcg gcgagcatca gatttttcag ctggtcaact ggtatatgcc
     3661 cacattgatt gcactgtatc tggttttcta tatttcctac cgcattttcc cgaaaaataa
     3721 atttcggcgt gttgcatttc tttccggcgt tatattcatt atcactgcgc tcctctgtgc
     3781 ctttgatgct gttacaggtt taaatcacag agtttattac atcagtgaac tggcttttcc
     3841 ctttggtgta ttcatttatg agtatgcaga cattcttgcc agttttttaa aaaagaaata
     3901 cgccttacca ctgatcgttg cggcagaact tattttttca ttttttggcc tgactgtgcc
     3961 tgaaaaaagc ttaccggatc tgattttcca caaccttatg atctttccgt ttggtctgct
     4021 tttgatctgg ctgctggata aattcaaagt cggcaatcga attataagcg caatgaaccc
     4081 ttatgctccg ttcctatatc tgtttcagtt tgtggttctt gatgtcatga agaactacta
     4141 tataacaaac gctcgtcctt ttggcatctt ctacttctgg ggcgttctgt ttttcacctg
     4201 catattggct gttgcacttc agcacctgta taattttatt ggggcagaag tacataagca
     4261 cttctgcccc aatcgttcaa ccctataaca ccttttgctt ttatgtttcc tgcatcatga
     4321 tgcggatacg gtcctgcatt tctttcttat ctttcggctt ccagacctgc ggcttgggcg
     4381 gcttgcgccg ctgcaccgaa taggccagcg gcagtagccg cagcgtcatc gtgcaccaga
     4441 aagaaaagga tgtgttatct gtaagatatg tcatcgtcat gtagctgaga ttgctcaagt
     4501 acagcagtgc ggtatcttca tccgcataat gtatccagaa gatcggcgta atgatatact
     4561 ggataccggc ccagaacaca aagcccggaa aacccatttc cacaaatact tttaaaatgt
     4621 cgttatggaa gggataagga tggttaataa tgcctgaatt gtaccattcg gtgacaatag
     4681 tgtccacata ctcaaagccg tggccaacgt aggtaatgga taaatcgtag taatcattag
     4741 caagactcca caggtagtca cgccccatca tgtcaatacc cgttatatgc agcagctttg
     4801 aaacaaggcc actgcgaact gcgtaaatat acagaaagaa aaacacgacc catgcaacac
     4861 cccacaggat gagcagcttc tttttgtcct tgaaacagcg gacgatcatc gtcacaaaaa
     4921 taaacagcac caccgccgga atggcgatac gcttcatgcc cacaaaaaag aaaaacgtac
     4981 aggccacaag catccgccag cggcggcgct tttcctgttt tgtgtcatgc ggggcaaacg
     5041 ctgcataata aagcaccaac tggccaaaca caaatgtgag atcatgtatt tccagattgc
     5101 gggcatatcc ctctgcttcg ccaaaggtga gcagacaccg cataagcgat tggatgcttg
     5161 ccgaaaggcc aaaggtagga atctccagaa ccatgatacc cgcatttgcc agacacaccg
     5221 caatggcaaa cagatcaatg gtttttgaac ccagcaggaa tactccgctc accgctgcaa
     5281 ggatcgaaat gctctggaac atcagcttgg agcaggcccg gatcatcgtg gataccgcgc
     5341 tgaagtccat cagccagatg accatggacc acaaaaatag cagcacaatc aaggacatat
     5401 agaccagtgt aggccagaac acctttttta cacgttccat ctctggatat atgaggccat
     5461 agacaattgc cataccgata acacccgcag taatgatctt aggcagacca cccaaaatac
     5521 tctgcatagt cttccagtcg ccaagtcccg ccagtgcaat aaaccccaca tagcagatgc
     5581 agatcagcct ttgccagaag gggctgtcct tataaaaaac ggaggacgga gtttttctgg
     5641 aataatcccg cttgacaatg atctcagaca atgtgcgcac gcgctgtttc tcctcttttg
     5701 tcggttctgt ggcgatagtt ttcttataag ttcaattata tgtttctgcc gaaactttgt
     5761 caatcgcgtc atcgggcaga aataacagaa gggtcaccgg cacagtcgat gacccttctg
     5821 ttattcattt tattttgcgc ccagacgcat tttgaagtcc tgatagccaa agtgcaccag
     5881 ttctctgcaa ttgccgtctg cgcccagcag ccagatgggc ggcaggggca tgccgttgaa
     5941 agtgttgttc ttgcaggtgg tgtagatggc catgtcgccg aaaatgagct tatcgccctc
     6001 agcaaggggt gcgtcaaagc tgtaatcccc gatgatatcc cccgcaaggc aggtggggcc
     6061 gcccaagcgg acagtgtgcg ctttctcccc cgcctcgccg gcgtccagca acggcgggcg
     6121 gtagggcatc tcgatgacat ccggggtgtg gcaggctgcg gacatatcca gaatggcaag
     6181 actggtatcc ccgttgcgca gggtgtccag cacggtagtg accagatagc ctgcgttcag
     6241 cgcccaagcc tcgccgggct ccagatacac ctgtacgccg tacttctgcc gcaccgaaag
     6301 aatgcagctt tccagcgtgt caagggcata acccgggcgg gtgatgtggt gtcccccgcc
     6361 gaagttgagc cactgcattc tgggcagcag gtctgcaaac tttttctcca ctgcggccag
     6421 cgttaccgcc agcgcatcgg cgtcctgctc gcacagggta tggaagtgca gaccgtccag
     6481 cagggcgggc agctccgggt gcgctgccac agcggcatcc cactgagcac gggtggtgcc
     6541 cagacggcta ccgggggcgc aggggtcgta aatttcgtgc ccctcctgcg tggagcactc
     6601 cgggttgatg cgcagaccga tgcttttgcc cactgccttt gccgccgggc cgaactttgc
     6661 cagctggctg ggcgagttga acacgatgtg gtcggcgtat tgcagcaatt cctcaaactc
     6721 gtctgcccgg taggcggcgc agaacacatg gttctctttt tccggcagct cttccctgcc
     6781 caagcggctc tcgtacaggc cgctggcctc ggtaccggcc agatagggtg ccagcaccgg
     6841 gtagacgtta aagttggaaa aagccttctg cgccagcagg atgcggcagc cggtgcgctg
     6901 ctgcacatcc agcaggatct caccgttgcg gcgcagctgg gcttcgtcca gcagatagca
     6961 gggggtaggc aggcggtgca gctgctcctc ggacaggttt gccagccccg caaagggcgg
     7021 gcggctgtcg cgcacccgca tcagtccacc agagccgggt tatggctctc ggagcggggc
     7081 aggccgtact tatccagtgc atccagatac ggatcgggat caaactcctc gacagtgtgc
     7141 acgcccttgg tggtccactt gccggtgagc agcatcaggg cgccgcacat agccggcacg
     7201 ccggtggtat agctgatggc ctgagagccc acttccttgt agcactcctg atggtcgcag
     7261 acgttgtaga tgtagtaggt cttgtccttg ccgtcctttt tgccggtaaa gatgcagccg
     7321 atgttggtct tgcccttggt acgagggcca aggctggcag ggtccggcag cagtgccttg
     7381 aggaactgga tgggcacgat ctcctgtccg ttgaagttga cgggggtggt ggacagcatg
     7441 cccacgtcct ccagacagcg catgtggtcc agatagctct ggccaaaggt catgaagaag
     7501 cggatgcgct ttgcctccgg gatgttcttt gccagagact cgatctcctc atggtgcagc
     7561 aggtacatat ccttgtcgcc cacctgatcg aagttgtact cccgcttgat gctcatagcc
     7621 ggaatttcta cccagtggcc gttctcccag tagctgccgg gtgcggacac ctcgcgcagg
     7681 ttgatctccg ggttaaagtt ggtggcaaag gcatagccgt ggtcgccgcc gttgcagtcc
     7741 agaatatcaa tggtgtcgat ggtatcaaac tcatgctttt tggcgtaggc gcagtatgcc
     7801 tgggtcacac ccgggtcgaa gccgctgccc agcagagcgg tcagaccggc ttcctcaaac
     7861 tttttggcgt aggcccactg ccagctgtaa tcaaagtagg cagagaagcc ggcctccttg
     7921 cagcgctttt catagatggc gcgccactcc gggtcgtcgg tgttctcggg ctcgtagttg
     7981 gcggtgtcca tgtagttgac gccgcaggca aggcaggcgt ccatgatggt cagatcctga
     8041 taaggcaggg cgatgttcat cacaaggtcg ggctggtagg ccttgatgag agcgatgacc
     8101 tcttccacct tgtctgcgtc cacctgtgcg gtggtgatct tggtagcggt ggtgggagcc
     8161 agctcggcag ccagcttatc gcactttgcc ttggtacggc tggcgatgca gatctcggtg
     8221 aacacctctg gcacctggca gcacttatgg atggcaacgg aggccacgcc gccgcagccg
     8281 atgatcagaa ctttgctcat gtcggttact cctttatctg taaattctct gtattctcat
     8341 acctgaaaac ccggccagcc cttgtccagc gcgatcaggg tctcgcgcag caccttgcag
     8401 gcggtggcgg tggaaacgcc ggtggtgtcc agcgtggggg caagctcgtt caggtctgca
     8461 ccgatgatgt tggccttggt cacagtgcgg atggcatcca gcagctgcaa aaagcttacg
     8521 ccgccagcct ccggggtacc ggtgcccggg aagcaggaag gatcaaggca atccagatcg
     8581 atggtcaggt acaccggcac cttgctctcg cacagctgtg cggtcagttc ggcaaggccg
     8641 gtaaaatcga acttgtgcat ctcggtgtgc tgagcagcaa actcaaactc tgcccggtct
     8701 ccgctgcgga tgcagaactg atggatgtgc ccatccccta ccagctcgtg gcagcggcgc
     8761 agcacacaag cgtggctgag ctttgcgccc agatagtcat cccgcaggtc ggcgtgggca
     8821 tcgaagtgga cgatgtgcag gtcagggtat ttcttcaccg cagcccgcac ggcacccagt
     8881 gtgaccagat gctcgccgcc cagcagcagc gggaacttgc cgtccttcaa aatctcctct
     8941 gcccgggcct cgatatctgc cagcgccagc tcgctggagc cgaagcacag ctccagatcg
     9001 ccgctgtcga acacatcaaa atcggtcagg tcggcgttct ggtaagggct gtaagtctcc
     9061 agaccgtagc tctcgtgccg gatggccgcc gggccgaacc gtgcaccggg gcggtagctg
     9121 gtggtggaat cgtaaggtgc accgtacagc acgatgctgg cggcgcggta gctgctgtcg
     9181 cagccgataa aggtctcaac gttggggtgc atcagtgttc ctccacttcc cgcagcatct
     9241 cctccagaaa agccggcagg tagaatgctc cgatatgcag tttggtggtg tagtagcggg
     9301 tgcgcatatt cagcgccttc cacgcttctg cgtccagatc atcaatggga tggtattttt
     9361 tgcttgcaaa gccgaacagc cagtagcccg ccgcaaaggt agggatatgt gcctgataca
     9421 cccggctgat ggggaaggtg gatgcgatgc gcttatggct gcgctgcatg gcgctggcgt
     9481 cctcggcgta gaaggggctg ccctgctggt tgaccatgat gccgtcctct ttcagagcgt
     9541 tgaagcagct gccgtagaac tcgcgggtga acagaccctc agaggggccg aaggggtcgg
     9601 aggagtccac gatgataagg tcgtactcct cctcgcagcg gcggatatac ttcagggcat
     9661 tctcaaaata gatatgcacc cggcggtcat ccatacggca ggcattgccg ggcagatagg
     9721 cgcggcaagc ctccaccacc tgcgggtcca tctccacaag gtcgatgcgc tccacacggt
     9781 cgtagcgggt cagctcccgc accacgccgc cgtctccggc tccgatgacc agaatatcct
     9841 tggcctcctt gtgcaccgcc ataggcacat ggacgatcat ttcatcgtag atgaactcat
     9901 cgcgctcggt cagcatcacg ttgccgtcca gcgtgagcac ccggccgaac tccggagtct
     9961 caaagatatc aatgcgctgg taatcgctct gcttggagta gagctgcttg ttcacacgaa
    10021 tgctgtgctt cacatccggg gtgtgaaact ctgaaaacca aaattccatc tctttccctc
    10081 cttatgccag aacattcagg tgcaaaattt cggggtcctc cgggccagtc atgctgcagc
    10141 ccttggcctt ggcgtactcg atatagttca aaatctcctt ggtgatgcgc tcgccgggtg
    10201 cgaggatggg gatgcccggg ggatagcaca tcacgaactc gctgcacacc atgccctcgg
    10261 tctcccgcag gggcaggctc tttttggggg cgtagaaggc ctcctgcggg ctggcagcca
    10321 ccacagggtc gatgtattcc tgactcagca gacccgagcc gtcggtacgg tagcggcgct
    10381 tgatctcagc cagcgcactg accagacgct ccacctcctg cgggcggtca ccgatggaca
    10441 ggtaggcaag gatgttgccg atatcgccga actcgatctg aatatcgtac tcatcgcgca
    10501 ggatgtcgta gacctcgatg ccggccagac cgatatccag cgtatggacg ctgagcttgg
    10561 tggtgtcgaa gtcaaagacg gaatcgccgt tgcacagttc cttgccaaag gcgtagtagc
    10621 cgcccacggc gttgatctcc tcgcgggcat actcggcaat atccgccacc tgatggaaca
    10681 cctgccgtcc ccgcagcgcc agattgcggc gggagatatc cagactggac atcagcagat
    10741 agctgccgga ggtagtctgg gtcaggttga tgatctgacg cacatagccc gggtgcacgt
    10801 tgggaccgat gagcagcagg ctggactggg tcaggctgcc gccgctcttg tgcatggaca
    10861 ccgaggccat atccgcgcct gccgccatgg cagaaaccgg caggccgccg ccaaagtaga
    10921 agtgggtgcc gtgggcttca tccgcaaggc agagcatgcc ggcgtcgtgc gccattttta
    10981 cgatggcacg caggtcggag cagatgccgt agtaggtggg gttattcacc agcacagcca
    11041 cagcgttggg gtgctccttg atggccttgg ccacctgctc ccgcttcatg cccagcgaga
    11101 tgcccaggcg cttatccacc tccgggttca catacaccgg caccgcgccg cacagcacca
    11161 gcgcgttcag cacgctgcgg tgcacattgc ggggcagaat gatctcatcg ccccgcttgc
    11221 aggcggtaag caccatgctc tgcacgctgc tggtggtgcc gcccaccatc aaaaaggcgt
    11281 gtgctgcgcc aaaggcatcg gcggcaagct cctcggcttc ccggataacc gacaccgggt
    11341 ggcaaaggtt atccagcggc ttcatactgt tcacgtccac gcccacgcac tgctgaccca
    11401 gaaaagcggt cagctccggg ttgccgcggc ctcgcttgtg gccgggcacg tcaaaaggca
    11461 ccacccgcat ctgccggaac cgctccagcg cctcgtaaat gggcgcacgg cgctgatcca
    11521 gccgggaacg cgctttgttt tcgttcatca tttcctccgt ccctgttctc ctttttgcac
    11581 aacaaaaaag cgcagacact gcacaaatgt gcagacctgc gcttggagca gctttttccg
    11641 cgctgataaa gcacccagcc gtaagtgccg gtgctgcgcg ttattcgcga tccaaaaaga
    11701 cggggtgatg agagtctata tagcaactac acttttacta ctcttattga ccgtttcaca
    11761 agtctgcgca taggctgcgc aatttcatgg ttgtaaagga accaacttat aaaatttgag
    11821 cttcaaactc aatcaataat ggcagcttgc gccgccggtc ggcagtggac ccggctgtcc
    11881 gtatggcctt agccccgttt gggcggtccc gagtaaattg ctttgaaaag actctgcaag
    11941 gcggcgtctc tcaaaatcaa caaaagaata acatgattcg ccccgtctgt caaccaaaac
    12001 tttttggcag tcgcccgctg cgggtgcgca gggcggcgct cggcgcgcaa aatagggcgt
    12061 tttgtgcaaa aagcagatgc ccttcccgcc gcagtatgct ataataaagg aacaatgaat
    12121 ggagaaagag ggtatatgga tggcactgcc aatcgccatc gtagaggatc agaccccgga
    12181 cgcccagcgg ctggaggagt tgctgcaaca gcagctgccc gaagccgagt gcacatggtt
    12241 tacctgcggg gatgattttc tccgcgccgc agcagagccc ggcctgtacg ccgtggtgtt
    12301 tctggatatc tgcatggcgg gcaccaacgg catcgagacc gcccgccgac tgcggcaggc
    12361 cgacccggag gtgctgatcg tattcgtgac ttcctccccg gaatatgtat gggatgcctt
    12421 tccggtgcac cccttcgatt atctgctcaa accctatcag gaggaaaaat tcgagcatct
    12481 tgccgccgag ctgcggcggg cgctgcgctg taaggagccg gaactggaga ttcgcattgc
    12541 ccgccagagc attcaactac cgctgcgtaa ggtgctgtat gccattgccc ggaaccacta
    12601 cgtccttatc accactgagg agggcgagta ccgcgccatg tgcagttttg cgcagatcga
    12661 agaaaagctt actgctctgg aaaactttat gagctgcaac cggggcgtta tcatcaacat
    12721 ggacaaggtg ctgcggttcg gggaggactg catcgagatc ctggacggca cccgcctgcc
    12781 ggtacggcaa aaggataaat gcaccctgct tgcccgcttt acacaatacc agttccgcca
    12841 catgcggcag gagctgcact gaggaaagga gcagccgcca tggatcttgc cctgttcggc
    12901 cgttattttc tggattttgc actgctgtac cccagcgcat ttctgtgtct ggccgctctg
    12961 tgggaaaagc tgcgcacccc caagcgcacc gcctgcatcg ctgccggatg catcaccctg
    13021 ctgtgcttcg gatgcgccgc gctctgcgcc gtgttcgggc tgagcagcaa ttctctcctg
    13081 cccgccatcg tgctggtttc cttctggctg ctgcgctggc gggtaacgcc ggaagtgacc
    13141 gtaagccaga ccgcgtttct gttttccatc tctgccgtga tgatggcggt gtgttccctg
    13201 ctgtcgacgg tactcaacgc ccaggccgag atctccaacc cacggacagt ctgccttgcc
    13261 tccacggcgc tgctgcggct gggcttggca gcggtactca ccgtgctgtt ctggttcact
    13321 gccgtgcagt ggggccggtg gctgctgcgg gagtacagcg gtgaagcctt ctggcagtct
    13381 gcgtggccgc tgcccgccct ctatgccgtt tttctggtat actgtatgcc gctgaacccc
    13441 gccgtggtgc tggtcgggcg actgaagatc atctcggtgc tggcggtgtc catctcgctg
    13501 ttcggcatct ttctgctgct gtacgagatg taccgcgttg cccgggagtt cacccgcaac
    13561 gcccggctgg accgggaaaa ccagctgctg gccatggaat cccgccggta catggagtta
    13621 cagacctatc tggacaacac ccgccgtctg cggcatgact tccggcagca tctgcatgtg
    13681 attgccggac tgaccgagac cgggcagctg gaggagctga aaagctatct gcaccagtac
    13741 gaaagcgagc tcagcgagca ccgccccagc ctgtgtgcca acgccgccgt ggatgcgctg
    13801 gccggatatt acgaccacgc ggccgggcag cagggtgttc ctgtggagtg gaagctggca
    13861 ctgccccggc agctgcccat gccggaggcc gacctgtgca ccattctggg caatctgctg
    13921 gaaaacgccc tgcacgccag ccagaagctg ccgccggagc agcgccgggt gcaggtgatg
    13981 gcgcagatgc tcagtcccgc catgctgggg cttgtggtag agaaccgtta cgacggcatg
    14041 ctgaaaaaac agcagggcgt cctgcgctcc accaagcacg agggcaccgg catcgggctg
    14101 gtatccgccg agacggtggt gcacaaatat aacggcaatc tgcacttgga gacagaggaa
    14161 cacctcttcc gggtgaatgt cctgctgaat ctgtagccac cggcagacta acgtgaaagc
    14221 gttcacaaaa agcagcgccg tcctttgcag agaggttttt ctgcgaaggg cggcgctgta
    14281 ttatttttca agcttctctg tgcttttttg tgcggcttcc agctcatcca cccgcttttg
    14341 cagggcggtg atcttatcgt ccattttcaa aaatgtccag accagaacgg ccagcaccag
    14401 cgcgggagga acgaccatcc acagggactg ctgacaccag agcagcagcg aatagccgcc
    14461 gaatacagta aaaataaata cggcaaacag gcttgcagcc agtacagcaa aaaatcccat
    14521 acagacagtc tcctttcagt tattcttccg tttcttcctc atccgggtcc agctcgatgc
    14581 tgaacacggc ttttttcagc ttgccgcagc cctgcgcctt cagaccggat ttatacggtt
    14641 cccccgccag atacagggca aagcgtccct cgcacagcat tccggcaatg ctggtaccgg
    14701 cggtgcctac ggtggtgtcg gcggcttcat cggtgggctt ggtgggcgtc agctccgcaa
    14761 ggcttacctc aaacagctca ctgccgtcta agtcggtctc cagcgtaatg tgattgtcgt
    14821 gccgctggaa cagcgccttg tcggaggtct ggggcgtgac agtgctcacg gtgaccaccg
    14881 ccttgtcccc atcaatgcgg gtgcgtccgg caggcagggt ggtgatatcc cgcgccatga
    14941 tgtactcgat cacggtgtcc agattgtcgc ttacgcccag atagttgggc aggttgttca
    15001 gggtatcgta gatcatggaa aaagtcctcc gtctgtgttg tttcagttac ctgtatggta
    15061 tcacaggtca gggacagatg caatatgtgt gcgggcggat gtcgcgagcc gcgcatctaa
    15121 aaaagccccg caggggcttt tttacccgcc ggactattcg gcgggtcgat gctgttcgaa
    15181 tccacccttg tagccccttt ttcaaggcag ataaaacaga aactccggta cccattggat
    15241 accggagttc ttggtgggcg cgggtggatt gcgcgagccg cgctgctaaa aacagcccac
    15301 tgggctgttt ttgcgctgtc ttctgcgaca gcgccgcagc tgttcgaat
//
