LOCUS       c00190_gnlPro..         4319 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HDDIGPKE_190.
ACCESSION   c00190_gnlPro..
VERSION     c00190_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 04:11:18
            Original ID  :: gnl|Prokka|HDDIGPKE_190
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4319
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..129)
                     /locus_tag="ctg190_1"
                     /transl_table=11
                     /translation="MEKPAAACYHLPGLFEFYELYRRFLPLYREHREYFYDWCTIGS"
     protocluster    1..4319
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[212:4318]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      213..4318
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..4319
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4319
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(213..1529)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg190_2"
                     /sec_met_domain="HGD-D (E-value: 9.9e-23, bitscore: 69.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYHYPKFTPEMKKTHTILIPNMAVTQFRLMEYALRCEGYKCELL
                     GNCGSAVAQLGLKYVHNDTCYPALLVIGQFLDALNSGKYDLEHTALLITQTGGGCRASN
                     YIHLLRKALVKAGYPQIPVASLNFSGLEKDSGFQMTLPLARKCIACIFYGDMLCALRNQ
                     VAPYENEKGAADRMVDRWIARLGRALLAGKGFTSREMKHTFPLIAKEFATIPVTRVPKV
                     KVGVVGEIYVKYSPLGNNDLQKFLESQDCEVNFPGLMGFVQYCAFNMGEDHVLYGGKLA
                     VKVGTDQFLNWLDSVERVMLKAETDAGFYAPGPFKELVEKPKGVISLGAKMGEGWLLTA
                     EMIELVQGGYGNIVCAQPFGCLPNHIVGKGMVNKIRALYPSANITPIDYDPSATRVNQE
                     NRIKLMLAVAKERLNAPAEAQPLTAEQLAGGAPQVGATV"
     CDS             complement(1619..4318)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg190_3"
                     /sec_met_domain="HGD-D (E-value: 2.3e-16, bitscore: 48.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 7.2e-40, bitscore:
                     124.8, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="FSTRVAVKRFMPKTDCVIELGGEDAKILFLTNGTEVRMNGSCAGG
                     TGAFIDQMATLLKMSADEMNKAAEQAQRTYTIASRCGVFAKSDVQPLINQGARTEDIAA
                     SIYKAVVNQTIAGLAQGRPIKGNILYLGGPLTFSTVLRKSFDEALNVTGTCPENSLLYV
                     ALGAALYADKEFVLTEVADALDKYAATATYASEPPLFASKEEYEAFHARHMSHSVPHVA
                     FSAHCGPVHIGIDSGSTTVKLVVVDEKSQILYTNYQPNLGNPLPLIREQLLKIYKEHPG
                     LQVASVTTTGYGEELVKNAFRCDYGLVETVAHFTAAKYFMPDVDFIIDIGGQDMKCFKI
                     EDGAISNIFLNEACSSGCGSFLQTFAQALGYDVKEFAALGLFADRPVDLGSRCTVFMNS
                     SVKQAQKDGASIENISAGLSISVVKNALYKVIRASSPEELGRKIVVQGGTFYNEAVLRA
                     FEKEMGVEVIRPDIAGLMGAYGAALYGLRQSHKNNQTTSAMMDEQELEKFAQQVVSVKC
                     GGCGNHCQLTVNTFADGRKFISGNRCDKPVTGKSEDNSLNLYAYKQQLLASYKPVPGKR
                     GSIGIPLCLGFYELLPFWYAFWTSLGFAVHTSPVSTRGLYLAGQATIPSDTACFPAKLS
                     HGHIKALSQMQLDAIFYPCLTYNVDEGLGDNHYNCPVVAYYPEVLAGNCPELEGKKFIY
                     DYVGIHRPKDFVHKMAKDVLPKYFGGISEREVQAAADAAYAEYEAHMAKIRVKGSEIID
                     EARRQGKRIIVLAGRPYHVDPEVNHGIDHLITRHGAAVVTEDSISNRVQKFPTSVLNQW
                     TYHSRLYAAAKYCTTQKDMDLVQLVSFGCGVDAITTDETREILQRGNKLYTQLKIDEIT
                     NLGAVNIRLRSLFAALDERDEAAAEKSE"
ORIGIN
        1 agagccgatg gtgcaccaat cgtaaaaata ttcccggtgc tcccggtaca gcggcaaaaa
       61 acggcggtac agctcgtaaa actcgaacag gccgggcaga tgataacagg cagctgcggg
      121 cttttccata gcggttcctt tcctgcaaaa agggagctgc tgcgtaaaaa tgccgtgcag
      181 cggctcccct gtttttatcg tatttgcttt tgttacacgg tagcgccgac ctgaggggca
      241 cccccggcaa gctgctctgc cgtaagcggc tgggcttctg cgggggcgtt cagccgctcc
      301 ttggccacag ccagcatcag cttgatgcgg ttttcctgat tgacccgggt ggcgctgggg
      361 tcgtagtcga tgggggtgat gttggcactg gggtacagcg cacggatctt gttcaccatg
      421 cccttgccca cgatatggtt gggcaggcag ccaaaaggct gtgcacacac gatgttgccg
      481 tagccgccct gcaccagctc gatcatctcg gcggtcagca gccagccctc acccattttt
      541 gcgcccagcg agataacgcc cttgggcttt tccaccagct ccttgaaggg gcccggcgca
      601 tagaacccgg cgtccgtctc tgccttgagc atgacgcgtt ccacgctgtc caaccagttg
      661 aggaactggt cggtgcctac ctttacagcc agcttgccgc cgtaaagcac atgatcctcg
      721 cccatgttga aggcgcagta ctgcacaaag cccatcagac cggggaagtt cacctcgcag
      781 tcctgacttt ccaggaattt ttgcaggtca ttgttgccca gcgggctgta cttgacgtag
      841 atctcgccca caacacccac cttgaccttg ggtacccggg tgaccgggat ggtggcaaat
      901 tcctttgcga tcagcgggaa ggtgtgcttc atttcccggg aagtaaagcc tttaccggcc
      961 agcaaggcac ggcccagacg ggcgatccag cgatccacca tgcggtcagc agcccccttt
     1021 tcgttctcgt agggagccac ctgattgcgc agcgcacaca gcatatcgcc gtagaagatg
     1081 caggcgatac acttgcgcgc cagcgggagg gtcatctgga aaccgctgtc cttttccaga
     1141 ccggaaaagt tcaggcttgc caccgggatc tgcgggtaac cggccttgac cagcgccttg
     1201 cgcagcagat ggatgtagtt ggaggcgcgg cagccgccgc cggtctgggt gatcagcaag
     1261 gcagtgtgct ccagatcata cttgccgctg ttcagcgcat ccagaaactg gccgatgacc
     1321 agcagcgccg ggtagcaggt atcgttatgc acatacttca gccccagctg tgccacggca
     1381 ctgccgcagt tgcccagcag ctcacacttg tagccctcgc agcgcagtgc gtactccatg
     1441 agccggaact gggtcacggc catgttgggg ataaggatgg tgtgggtctt tttcatctcc
     1501 ggggtaaatt tgggataatg atattccata ggttcctcct atgttactct aaacaagata
     1561 gtctccgcaa aagcttcccc cgccggggga agcccttcag cctatctcag gatttctttt
     1621 attctgactt ttctgcggcg gcctcgtccc gctcgtccag tgcggcaaac aggctgcgca
     1681 gacggatgtt cacggcaccg aggttcgtga tctcgtcgat cttcagctgg gtgtacagct
     1741 tgttgccccg ctgcaaaatc tcgcgggtct cgtcggtggt aatggcatcc acgccgcagc
     1801 cgaaggacac cagctgcacc agatccatat ccttttgggt ggtgcagtac ttggcggcag
     1861 catacagacg gctgtggtag gtccactggt tcagtacgct ggtggggaac ttctgcaccc
     1921 ggttggagat gctgtcctcg gtgaccaccg cagccccgtg gcgggtgatc aggtggtcga
     1981 tgccgtggtt gacctccggg tctacatggt aggggcggcc tgccagcacg atgatgcgct
     2041 tgccctgacg gcgcgcctcg tcgatgatct cgctgccctt tacccggatc tttgccatgt
     2101 gtgcctcgta ctccgcatag gcggcatcgg ctgcggcctg cacctcccgc tcggagatgc
     2161 cgccaaagta cttgggcagc acatcctttg ccatcttgtg cacaaaatcc ttggggcggt
     2221 ggatgcccac gtaatcatag atgaactttt tgccttccag ctccgggcag ttgcctgcca
     2281 gaacctccgg gtagtaggcc accaccgggc agttataatg gttgtcgccc aagccctcgt
     2341 ccacattgta ggtcaggcag gggtaaaaga tggcgtccag ctgcatctga ctcagagcct
     2401 tgatgtggcc gtggctcagc tttgccggga agcaggcggt atcgctgggg atggtggcct
     2461 gtccggccag atacagcccg cgggtggaca ccgggctggt gtgcaccgca aagccaaggc
     2521 tcgtccagaa ggcgtaccag aagggcagca gctcgtaaaa gcccagacac agcgggatac
     2581 cgatagaacc gcgcttgccg ggcacaggct tgtagctggc cagcagctgc tgcttgtagg
     2641 catacaggtt caagctgtta tcctcacttt ttccggtaac gggcttatcg cagcggttgc
     2701 cggagatgaa cttgcggcca tcggcaaagg tgtttacggt cagctggcaa tggttgccgc
     2761 agccgccgca cttgacgctg accacctgct gtgcaaactt ttccagttcc tgctcgtcca
     2821 tcatggcaga ggtggtctgg ttgtttttat ggctctggcg caggccgtac aaagcagcgc
     2881 cgtaagcgcc catcaggccg gcaatgtccg gccggatgac ctccacgccc atctcttttt
     2941 caaaggcgcg gagcacggct tcattataga aggtaccgcc ctgcaccacg atcttgcggc
     3001 ccagctcctc cgggctggag gcgcggatca ccttgtacag cgcgttcttg accacgctga
     3061 tggacaggcc tgcggagata ttctcgatgc tggcaccgtc cttttgcgcc tgcttgaccg
     3121 agctgttcat gaacacagtg cagcggctgc ccaagtccac cgggcggtct gcgaacagac
     3181 ccagtgcggc aaactccttg acatcatagc ccagcgcctg cgcaaaggtc tgcaaaaagc
     3241 tgccgcagcc ggaggagcag gcctcgttca ggaagatgtt gctgatggca ccatcctcga
     3301 tcttgaagca cttcatgtcc tgcccgccga tgtcaatgat gaagtccaca tccggcataa
     3361 agtacttggc agcggtaaaa tgcgccaccg tttccaccag accgtaatca cagcggaaag
     3421 cgttttttac cagctcctca ccgtagccgg tggtggtgac gctggccacc tgcagccccg
     3481 gatgctcctt atagatcttg agcagctgct cccggatgag gggcagcggg ttgccaaggt
     3541 tgggctgata gttggtgtac aaaatctggc tcttttcgtc caccaccacc agcttgacgg
     3601 tggtagagcc ggagtcgatg ccgatatgca ccggcccgca gtgggcacta aaagccacgt
     3661 ggggcacact atgggacatg tgccgtgcgt ggaaagcctc gtactcctcc ttgctggcga
     3721 acagcggcgg ctcgctggca taggtagcag tggcggcgta cttgtccagc gcatcggcca
     3781 cctcggtgag cacaaattcc ttgtcggcat acagggcagc gcccagcgcc acatacagca
     3841 gactattttc cgggcaggtg ccggtcacgt tcagcgcttc atcaaagctt ttgcgcagca
     3901 cggtgctgaa agtgagcggg ccgcccagat aaaggatatt gcccttgatg gggcggccct
     3961 gtgccagacc ggcgatggtc tggttgacca cagccttata gatgctggcg gcgatatcct
     4021 cggtgcgggc gccctgattg atcagcggct gcacatcact tttggcaaac acgccgcagc
     4081 gggaggcgat ggtataggta cgctgcgcct gctctgccgc cttgttcatt tcatcggcgc
     4141 tcatcttcaa cagggtagcc atctggtcga tgaaggcacc ggtgccgccg gcacagctgc
     4201 cgttcatgcg cacctcggtg ccgttggtca aaaacagaat cttggcatcc tcgccgccca
     4261 gttcgatgac gcaatcggtc ttgggcataa agcgcttgac cgccacgcgg gtggagaac
//
