LOCUS       c00005_gnlPro..        14920 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GNPNIOLG_5.
ACCESSION   c00005_gnlPro..
VERSION     c00005_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:16:48
            Original ID  :: gnl|Prokka|GNPNIOLG_5
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 116123
            Orig. end    :: 131043
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14920
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[126123:129351]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13228
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14920
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14920
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1406..1891)
                     /locus_tag="ctg5_101"
                     /transl_table=11
                     /translation="MIKINIICIGKIKEKYFTDAIAEYAKRLTAFCKFNIIELSEERIK
                     SNIPNRSQIDEVIFSEGKRIMQKISPSDYVVAMCIEGKSMSSEELSKLIDNASVSGKST
                     VDFIIGGSYGLDESVKKRADVRLSMSRMTFPHQMARMILSEQIYRAFEISSNGKYHK"
     CDS             complement(1913..2701)
                     /locus_tag="ctg5_102"
                     /transl_table=11
                     /translation="LARAVPLFSGSKGNSYYIGSASEGVLIDAGRSCKQIENAMLANGL
                     DMGSIGAVFITHEHTDHCSALRVLAKRYGFKVYSSLGTLNALRAGNKLDPNTDADVITD
                     EVVIGNMRVQRIDTPHDAAESCCYRVTAPDGKSALIATDMGVMLPNVRTAAEQSDFVVL
                     ESNHDINMLKNGFYPYPLKQRILSNRGHLSNEACAKELVNLVEKGTLRLMLGHLSEENN
                     TVPLAMSTSVDLLTSNGMKYKSDYSLDVAPSVSTTKAIIF"
     CDS             complement(2824..4116)
                     /locus_tag="ctg5_103"
                     /transl_table=11
                     /translation="LEKFVVTGGKPLSGEVTISGAKNAAVAIIPAVILCDEPCQIENIP
                     NISDVSLISRILQQMGANVRRINRSSLYIDPTKIRTCNAVTDLVRGMRASYYLLGALLG
                     KYGKAKVALPGGCNFGVRPIDQHLKGFEALGATTQLVDGAIIEAECDNLVGTHVYLDVV
                     SVGATMNIMLAASKAKGQTIIENAAREPHIVDLANFLNSMGADVRGAGTDVIKIRGVEY
                     LHGITYSIIPDQIEAGTYMCAAAATRGCITVKNITPKHLESISAKLREMGVKITEYDEA
                     LKVDASSAPLKRCNIKTMPHPGFPTDCQPQFAALLMSVPGTSIINENVWDNRYQYVSEL
                     IRMGAQISVEGRLAIIEGGVPLTAAPVKATDLRAGAAMIIAALEINGTTEISNIQFIER
                     GYEDVVEKFRALGADIKKVYFTGDNEQELGA"
     CDS             4797..5513
                     /locus_tag="ctg5_104"
                     /transl_table=11
                     /translation="MSETAKEPKKISKRSSEEKIEIIVAIFLGITALATAWASWIGSLH
                     GGNQATNYTKSNNLSSEGNSMWNEASQNLMQDMITWNDINEANLNYQYAESKNDKAEME
                     KYQYQIDQLMSDNCTEEFLEAINWAMDQKENVTPFMKDGYTESYFAEAKATIEESDKLL
                     EQGKKDNANGDAFGLVSVIYSVVLFMLGIVGTFKNLPNRRIVLGVAVVGFILATIYMFT
                     IPMPTGFNILSYFGMA"
     CDS             5716..6033
                     /locus_tag="ctg5_105"
                     /transl_table=11
                     /translation="MENKEKTTNPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALSMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
     CDS             6046..8370
                     /locus_tag="ctg5_106"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCAHCAGKIEAKIAETNGFEDVSFNFATKLLNFKS
                     EKQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLNCAHCAGKIEAKITETDG
                     FEDVSFNFATKLLNFKSEKQNPVSEIQAICDSIEDGVTVVDKTPKNDITTKAEPKITKK
                     KINRDTIFLAISIVLAVVSEILHLTLDGVTAVHYVVLAACFVATLLSGYKVFIKGAKNI
                     LKLRIDETTLMAVAVIAAFCLGDFVEAAMVTILFSIGEIFEDRAVDASRRDIEKLANIR
                     PDTATIIVDGAEQIVPAESVEIGSIIEVKPYERVPLDGIIIKGKTTLDTSALTGESLPV
                     DAGEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDAAAQKGNSEKLISRFASV
                     YTPVVVLIAVAIAVIPPLCGLGAFSEWLYRALVCLVASCPCAIVISVPLSYYSGIGAAS
                     EVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTVGSYSADEVLALAAASEK
                     YSAHPIASAIREKAIGLELPELSDYSESAGHGTSAVYNGKTIQCGGSKILSDEQKKIAN
                     KDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLKALGVKNTVMLTGDRQQPAENVKNE
                     LGLSECHAELLPAQKLELFKGLKSKSKGACFVGDGINDAPVLSASDCGIAMGFGSEAAI
                     EASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKALVIILAAFGLAQIWMSVI
                     ADTGVSVVCVLIAARLLKKKY"
     CDS             8569..9804
                     /locus_tag="ctg5_107"
                     /transl_table=11
                     /translation="LKKIFLLLVTALFLLSLYGCNTSSSSNNPTEQTTVTNTDDLSLDS
                     DTDSETEFNNDLEIYYNDKKIDNLNLFDALMPTEDGLIYSKINETSPNEIEYYRYYLDK
                     KSSIKLGSIKDWTMQINDKAYVNNHLCFMASTGDITDEENRTLEFIDIDLNKNKMTTVF
                     SDKGGFPYDTITGADNLVIITKVLNNGTSLELYDTETQKFKQLKYLEFDDKNCVGKTIR
                     KVSIDDSTKTICLLVLDCVSETDVSLKIETYDYDMNFLKSYDISDISDDSNELIQGVQF
                     FDFRNNYLIYQNFSMTRCIGYIRDRKLQKSDMIDNIDDTYSMAQTPQKGYNTVLSFKDV
                     DLERNIYLFNTIDKTMKKTKFKPEEENYYIGSMSRTGKDNLMIITTPDNADKKSDLNSR
                     IYFTKLSDLNFQ"
     CDS             10001..11623
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_108"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.4e-42, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             11636..12127
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_109"
                     /sec_met_domain="ALS_ss_C (E-value: 1.5e-29, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             12188..13228
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_110"
                     /sec_met_domain="IlvN (E-value: 6.8e-83, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4.8e-60, bitscore: 194.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKIAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(13520..14920)
                     /locus_tag="ctg5_111"
                     /transl_table=11
                     /translation="GVKISWGKVSGATKYRVYYKGSKGWTRMVDTTSTSYIDKDVSSGR
                     NYTYTVRCITSDAKKFTSGYNPTGKSVKYVATPKISKLEVTYDGVKLTWNKVAGAEKYR
                     VYYKDRNGWTKLADTTGTTMLDMNVVSKEFDLSVDDIYYTVRCISKDAKSFTSGYDSKG
                     TPIGNHQDCPEIYSIGAVNNGVEMHWTGDAPKFRVYIKENGSWKRIAETYDNYYVHKGA
                     KSGSNTYTVRGVSKDGKKFTTMFNPTGVTYRYKTSDKTRDAYINYMMNHQSEWMPSLGS
                     NHNLSGVMFLDFDFDGVPELVAQKADSNEYSFHSVVYKFEDGKLKRVGNVNDGFAIYYN
                     KTAKKYEVHDLKISLNVDDGYYWSGNSIITYDGENLFANMYSARGVGEESNNNIYYNYF
                     DGNDKNISRAKYNEINLKQFNNCVNAHMFTEFIATGYGDNSVWSENTTAENKQSLLDAY
                     NSFSYEKY"
ORIGIN
        1 aattcgagcg gcggcaaagt tgtctgacgg ggctttttgc ccttttgaac cttgagatag
       61 ccctgctcgg taagttcctc acgaatttgt gcaaggtctt tttcattctc cgcacggtca
      121 accgtatcga gaaccgagtt aatataatca agctcttccc tgcccttttc aagctgttct
      181 ttgagcataa tttcggcatt tttagccttg cggtaatcct tgtaatactt ctgggcattt
      241 gccgaaggtg agattgccgg attaagcttt atgcgtaaaa ttgcgttgtt ctcatcgtaa
      301 aagttttcaa catcaacata ctccgcacca cgctcaatgc gatagatatt tgcctgtaaa
      361 aggtcaccgc atatgcgaag atgctcacgg tctgcacagc gttcaagttc actcttctgc
      421 tttgcaattt ttcgtgcaag cctttcaagt gtgttgttca aaagctttgt aagactttgt
      481 gatttcaccc tcattctgtc acgactgtca cgagcctcat agaatccgtc aagcaaagcg
      541 gagaagcttt ccttactctc aacctttgca aaatcgccgt actgctcaac attcataaag
      601 caaaagtcca taggcttgcc gtcctcacga taaaccacaa caggcttgcc cgaacaatcg
      661 ctgcaaacgc ttttcagctt ttcgatttca actgcgagtc ggtcaaaaag cacaccctca
      721 attctgtttg ttgcgccctc cataaccttg tattcaatct cacggcatac aatcggagaa
      781 acaccctcaa ttgtccttaa cagcgccttg ttaagcggca tttccgtgtc aagatttttt
      841 acggctgtac acacatcaag caccgaacat ttaaggagat tcagcttgtt ctgcgattcg
      901 ggaagttcgt attttatatt cggcagtaca agtcttttac tgctcattgt aagatctaca
      961 cgcttgagcg agtcgatgat aacaccgttt gaatcgacaa taattatgtt gctgtacata
     1021 cccataattt cgcatacaac agttatcatc acagtatcgc cgagttcgtt cacgcactcg
     1081 aaatcgagca taagaacacg gtcacaaccg ttctggcgaa gtcccacaag ctttcctccg
     1141 ccgattcttt ttcgcaaaag catacagaac atcggaggtt gtgcaggatt ttcgggtgtt
     1201 gaggaacaga agttcactct cggtgaattt gctcgtgccg aaagcaacag ctttttgttg
     1261 ccggaaaagg ttctcagccc gaacacaagc tcctctctgt tcggctgata aatctgcgac
     1321 acccttgcac cgagagcctc tttttctatt tcacttttaa tatgtcttaa aaaaattccg
     1381 tcaagcgcca tagtaactcc gtaaattatt tatgatattt accgtttgat gaaatttcaa
     1441 atgcacggta aatctgttcg cttaaaatca ttcttgccat ttggtgagga aaggtcattc
     1501 tgctcattga aagacgaaca tccgcccgtt ttttaaccga ttcgtcaagt ccgtagctgc
     1561 cgccgataat aaaatcaacg gtgctttttc cgcttacaga cgcattgtca atcagctttg
     1621 aaagctcctc actcgacata gactttccct caatacacat tgcaacaaca taatccgaag
     1681 gcgaaatttt ttgcatgatt cgttttccct cagagaaaat aacctcatca atctgcgacc
     1741 tattcggtat gttgctctta atgcgttctt ccgaaagctc aataatattg aatttacaaa
     1801 atgcggtcaa gcgttttgca tactctgcaa ttgcgtcggt aaaatatttt tccttgattt
     1861 tgccgataca aattatgtta atcttaatca tattcctctt gtctgtttaa ggttaaaaga
     1921 tgatggcttt tgttgtgctt acactcggag caacatcaag cgaataatcg cttttgtact
     1981 tcattccgtt tgatgtgagc aggtctacgg atgttgacat tgcaagcgga acggtattat
     2041 tttcttcgct gagatggccg agcataagtc ttaaagttcc cttttcaaca aggttaacaa
     2101 gttcttttgc acatgcctca tttgaaagat gtcctctgtt tgaaaggatt ctctgcttta
     2161 gcggataagg ataaaatccg tttttgagca tattgatatc gtgatttgac tcaagcacaa
     2221 caaagtcgct ctgctctgcg gcagttctga cattgggcaa cataacgccc atatcagttg
     2281 ctataagtgc ggattttccg tcgggagcag taacacggta gcaacagctt tccgccgcat
     2341 cgtggggtgt gtcaattcgc tgaacacgca tattgccgat tacaacctcg tcagttataa
     2401 catctgcatc cgtgtttgga tcaagcttat tacctgccct caaagcattg agcgtaccaa
     2461 ggcttgaata caccttaaag ccgtaacgct ttgcaagcac acgcaacgca ctgcaatggt
     2521 cagtgtgttc gtgagttata aaaaccgccc cgatactgcc catatcaagt ccgtttgcaa
     2581 gcatggcatt ttcaatctgc ttgcatgaac ggcctgcgtc aatcagtacg ccttcacttg
     2641 ccgaacctat gtagtagctg ttccccttac ttccgctgaa cagcggtact gctcttgcca
     2701 aaacaatcaa tccttatctt tagtataacg aatatgataa cacaaatttt aaaatttgta
     2761 aattatctca caaaaaagcc gttctcacaa agaaaacggc tttgatttct aattaaattt
     2821 tagtcaggca ccaagctcct gctcgttgtc tcctgtaaaa tacacctttt tgatatctgc
     2881 accgagtgct ctgaactttt caacaacatc ttcatatcca cgctcaatga actgaatatt
     2941 agaaatctct gttgtaccgt taatttcaag agcggcaata atcatagccg cacctgcacg
     3001 aaggtcggtt gccttaacgg gagccgctgt gagcggaaca ccgccctcaa tgattgcaag
     3061 tctgccctca acagaaatct gtgcacccat tctgataagc tcgctgacat actgatagcg
     3121 attatcccaa acattctcgt tgatgatgct tgttccggga acgctcataa gcaatgcggc
     3181 aaactgcggc tgacagtctg tcgggaagcc gggatgcggc attgtcttga tgttacagcg
     3241 cttgagcgga gcagatgacg catcaacctt gagagcctca tcatattccg taatcttgac
     3301 gcccatctca cgcagctttg cactgattga ttcaagatgc ttcggtgtaa tattctttac
     3361 cgtaatacaa cctctggttg cggcggcggc acacatatat gttcctgcct caatctggtc
     3421 gggaataatc gaataagtaa tgccgtgaag atactcaacg ccacggattt tgataacatc
     3481 cgtacctgca cctctgacat ccgctcccat tgaattaagg aagttcgcaa ggtcaacaat
     3541 atgcggttct cttgcggcat tttcaataat ggtctgtccc tttgcctttg atgcggcaag
     3601 cataatgttc attgttgcac caacggacac aacatcaagg tacacatgtg taccgacaag
     3661 gttgtcgcat tctgcctcta taatcgcacc gtcaacaagc tgagttgtcg caccgagagc
     3721 ctcaaagcct ttaagatgct ggtcaatcgg acgcacgcca aagttacagc cgcccggaag
     3781 agccacctta gccttgccgt acttgcccaa aagtgcgccg aggagataat atgacgctct
     3841 catacctctt acaaggtcgg tcacagcatt gcatgtgcgg atttttgtag gatcaatata
     3901 taaggacgaa cggttgattc gtcttacatt agcacccatc tgctgaagaa ttctgctgat
     3961 aagtgataca tcgctgatgt taggaatatt ttcaatctgg cacggctcat cacaaagaat
     4021 aactgccgga ataattgcaa cggctgcatt tttcgcaccg ctgattgtca cttcacccga
     4081 taatggcttt ccgccggtaa ctacgaactt ctccaattgt tacaccccaa ttaatgtgta
     4141 gaagatactt ttaactaaat aagctaaata tctgaaaatg tatatctata tagtgtataa
     4201 gtaaaaatca aaaattatac gaatctaaaa attcataatg agaactaatt tgttacattt
     4261 tattaaaaac gaacccactc ggttacgcag atgtaattta acaattctct tacagaaaat
     4321 gatactacaa aattgtagta aagtcaacgg aataataaaa ctgtaatcta tttttgggca
     4381 agttgtactc aaattattaa tttgttgctt tttttgtttt taatataacc aaccatactt
     4441 tttaaaatcg ttttttccta aaaagaagta attaatcaaa gcaatttttt gtaaaattat
     4501 tacaaattga aacagttatt atattttctt aattgaaaat ttgcaggcaa atctatcgta
     4561 tatttattct ttgcaaatca aacgaataaa acaaaaatat ttaaaggtaa attttttaaa
     4621 aatcacagac aaaatgatta ttatgccgaa aaaaagactt tactgccact tgcattgaat
     4681 ttaaaacttt tatcaattat gattgaaaca gaatcagtcg gcaagtgtcc ttttacatta
     4741 taataacgac aaaattaagg cattgcggca aatttttaat taacggggga ttcagaatga
     4801 gcgaaacagc aaaagaaccg aaaaaaataa gtaaaagaag cagtgaagaa aaaattgaaa
     4861 ttattgttgc gatttttctc ggaataaccg cactcgccac agcatgggca tcgtggatag
     4921 gttcacttca cggcggaaat caggcgacta actacacaaa aagcaacaac ctctcatcag
     4981 agggcaactc gatgtggaat gaggcttctc aaaatcttat gcaggatatg atcacatgga
     5041 atgacatcaa tgaggcaaac cttaattacc aatatgcgga atctaaaaac gataaagcgg
     5101 aaatggaaaa atatcagtac caaattgatc agcttatgag tgataactgt acagaagaat
     5161 ttcttgaggc aattaattgg gcaatggatc aaaaggaaaa tgtaactccg tttatgaagg
     5221 acggttacac cgaaagctat tttgcagagg caaaagctac aattgaagag tcggacaaac
     5281 ttcttgaaca aggtaagaaa gataacgcaa acggtgacgc attcggtctt gtaagcgtaa
     5341 tttactcggt tgtactcttt atgctcggta tcgtaggcac attcaagaat cttccgaata
     5401 gaagaattgt gctcggtgtt gcagttgtag gttttattct tgccactata tatatgttta
     5461 caattccgat gccgacagga ttcaatattc tcagttattt cggaatggca taaaacaaaa
     5521 tattctgtac tcacagcggt gaaagcaaat gcttttgccg ctgttttttt gtaaaaaatc
     5581 aaaaaaatat tacacttttc cctctatgtc tattgacttt ctaaagagag aatgctatat
     5641 tataattaac atatgagcat atcttcatat gttcaagtat aactattaac ctgagagaaa
     5701 attaagggga cgcctatgga aaacaaagaa aaaacaacca atcccgaaat gcccgacatt
     5761 gatgtgctgt ttgagcttgc agaccttttt aaggttttcg gtgattcaac ccgacttcgc
     5821 attatgtaca ccatttcgga aaatgaaatg tcggtgctca acattgctga agctctcagc
     5881 atggagcaaa gcacaatttc ccaccaactg cgtgtgttaa ggcagaacaa gctggtgcgt
     5941 gttcgccgtg aaggaaagca gatttattac agccttgacg atgaccatgt gaaacgaatc
     6001 atagaaatgg gacttgacca tgttcttgaa taaggaggga gacatatgag gtacaaatat
     6061 cagcttgaca atctcaactg cgctcattgt gcaggcaaga ttgaggctaa aattgcagaa
     6121 acaaacggct ttgaggatgt aagcttcaat tttgcgacaa aacttctcaa tttcaaaagc
     6181 gaaaagcaga atcctgtttc cgaaattcag gcaatttgcg acagcattga ggacggtgta
     6241 accgttgttg acaaaactcc gaaaaccaat ctcaaaaaat acacctacac tttagacaat
     6301 ctcaactgcg ctcactgtgc aggcaaaatt gaggctaaaa ttacagaaac agacggcttt
     6361 gaggatgtaa gctttaattt tgcgacaaaa cttcttaact tcaaaagcga aaagcagaat
     6421 cctgtttccg aaattcaggc aatctgcgac agcattgagg acggtgtaac tgttgttgac
     6481 aaaactccga aaaatgatat cacaacaaag gcagaaccca aaatcacgaa aaagaaaatc
     6541 aaccgtgaca caatcttcct tgcaatttca attgtacttg ctgtagtgtc cgaaattctc
     6601 caccttacac ttgacggtgt tacggctgtt cattatgttg tactcgcagc gtgttttgtt
     6661 gcaacacttc tttcgggtta caaggtattc atcaagggtg caaaaaacat tctaaagctg
     6721 agaattgacg aaacaacgct tatggctgtt gcggtaattg cggcattctg tcttggagat
     6781 tttgttgagg ctgcaatggt aacaatcctc ttttctatcg gtgaaatttt tgaggatcga
     6841 gcagttgacg catcccgccg tgacattgaa aagcttgcaa acattcgtcc cgatacagca
     6901 acaattattg ttgacggtgc ggaacagatt gttcctgccg aaagcgttga aatcggaagt
     6961 atcattgaag tcaagccata cgaaagagtt ccgcttgacg gcattattat caaaggtaaa
     7021 acaactctcg acacatcggc tctcacaggc gaaagccttc ctgttgatgc aggcgagggc
     7081 agtgaggtac tcagcggcgc aatcaacggc agtaacctta ttaccgtcaa aaccacaaag
     7141 catttcggcg acagtaccgc aacaaggatt cttcagcttg ttgaagatgc cgccgctcaa
     7201 aagggcaaca gcgaaaagct tatttcaaga tttgcctctg tttacacacc ggttgttgta
     7261 ctcattgcag ttgcaatcgc agtaattcct ccgctttgcg gactcggagc attcagtgaa
     7321 tggctatacc gtgcgcttgt ttgtcttgta gcgtcatgtc cgtgtgctat tgttatttcc
     7381 gtacctctct cctactattc gggtatcggt gcggcatccg aagtcggtgt actcatcaag
     7441 ggcggaaaat atattgaggc tcttgcaaaa gcagacacat tcgtattcga taaaacaggc
     7501 acgctcacaa gcggcaagct cagcgtaaac aaggttaata ctgtcggttc atacagtgcc
     7561 gacgaagttc ttgctcttgc cgctgcaagc gaaaaatatt ccgctcatcc gattgcctcc
     7621 gcaatcagag aaaaggcaat cggtcttgaa cttcccgagc tttcagacta cagtgaaagt
     7681 gccggtcacg gaacaagcgc agtttataac ggcaaaacta ttcagtgcgg cggttcaaag
     7741 attctttcgg acgaacagaa aaagattgca aataaagacg attctgtttt cgtaatttat
     7801 gacggtcagc ttatcggttc gctcaatgtc agcgatacgg taaggcctga ggcaaaagag
     7861 gttatctcac agcttaaagc gctcggtgtc aagaacacgg taatgctcac aggtgacaga
     7921 caacagcctg ccgaaaatgt taaaaacgaa ctcggacttt ccgaatgtca cgcagagctt
     7981 ctccctgctc aaaagcttga gcttttcaag ggcttgaagt caaaatccaa gggtgcttgc
     8041 tttgtgggcg acggcatcaa tgatgcccct gttctttcgg caagcgactg cggtatcgca
     8101 atgggattcg gcagtgaagc cgctattgaa gcgtcagacg cagttctcgc atcaggcaca
     8161 ctcaaacagc ttccaaaggc aattaaaatt gcaagaagtg ttatcaacac cgtcaagggc
     8221 aacatcatct ttgccctctc aatcaaggct cttgtaatta tccttgccgc attcggtctt
     8281 gcacaaatct ggatgtctgt tatcgctgac acaggcgtca gcgtagtctg cgtactcata
     8341 gccgcaagac tcctcaaaaa gaaatattga tttttttgca aatcatatca tttattatga
     8401 taaagcaccg tgagctttca caagtttcac ggtgctttca tttgccaaaa tttttctaaa
     8461 cataatctta tattatagta ttttgaaatt attgactttt ataattatat aaattataat
     8521 gtttttgtca gcgcttgtaa ctgataaata aacttcggag agattaattt gaaaaagata
     8581 tttttattat tagtaaccgc tttattttta ctttcattat acgggtgtaa cacttcttca
     8641 tcaagcaata accccactga acaaacaacc gtaacgaata cagatgattt atctcttgat
     8701 tcagatacag attctgaaac agaatttaat aacgatttgg agatttacta taacgataaa
     8761 aagattgata atttaaatct tttcgatgca cttatgccaa ctgaggatgg actcatatat
     8821 tcaaaaatca acgaaacttc tccgaatgaa atagaatact acagatacta tttagacaaa
     8881 aagagcagta taaaactcgg ctcaataaaa gactggacaa tgcaaattaa cgataaagcg
     8941 tatgtaaata atcacttatg ttttatggca agcacgggtg acattacaga tgaagaaaac
     9001 agaacccttg aatttattga tatagacctt aataaaaaca aaatgactac tgtcttttct
     9061 gacaaaggcg gttttcccta tgataccatt acaggtgcag acaatcttgt cataatcaca
     9121 aaagtattaa acaacggtac ttctttggaa ctgtatgaca ccgaaacgca aaagtttaaa
     9181 caactgaaat atttagagtt tgatgataag aactgtgtag gaaaaactat aagaaaagtt
     9241 tcaattgacg acagcacaaa aacaatttgc cttttggttt tggactgtgt ttcggaaaca
     9301 gatgtttctt taaaaataga aacctatgac tatgatatga attttctcaa aagctatgat
     9361 atatccgata tttcagatga ttcaaatgaa ctgattcaag gagtgcagtt ttttgatttc
     9421 agaaacaact accttatcta tcagaatttt agtatgacaa gatgtatagg ttacataagg
     9481 gacaggaaat tgcaaaaatc cgatatgatt gacaacattg acgacaccta ctctatggct
     9541 caaactccac aaaaaggata taatacagtt ttatcattta aagatgttga tttagaacgg
     9601 aatatatact tatttaatac cattgacaaa acaatgaaaa aaacaaaatt caaacctgaa
     9661 gaagaaaact actatatcgg ctcaatgtca agaactggaa aagataattt gatgataata
     9721 actactcctg ataatgcaga caaaaaaagt gaccttaatt caagaatata ctttacaaaa
     9781 ttaagcgact taaattttca gtaaacaggc ggtaaaaatc aattaaaatc cattttgcaa
     9841 attatctgtc aaaatcctgc aaaaaattta atttatgggc aatactgctc tttacttttt
     9901 aaggtattta ttgtataatt agcggtaaag taaaaaggta tatttaatgt tacaaaacac
     9961 cttttgctca caataaaaag gataggaggg acaaaacata atgatcagcg gtgctgaaat
    10021 tatggtaaaa tgtttggaag ccgagggcgt tgacatagtc tttggttatc ccggtgcggc
    10081 tatctgccca ttttacgata aagtttacga ttcgagcatt acccacattc ttgttcgtca
    10141 ggaacagaac gctgctcatg cggcaagcgg ctatgcaaga tgcagtaatc gtcccggtgt
    10201 ttgcgtggca acttccggtc ccggtgcaac caacctcatc acaggcattg caaccgccta
    10261 tacggactct attccgattg ttgccattac aggtcaggtt cgttccgacc ttctcggcag
    10321 agatgtcttt caggaagctg acatcacagg agcttgtgaa ccgtttgtaa agcacagtta
    10381 tctcgtcagc aaaacagaag accttccgag agttttcaaa gaggctttcc atattgcctc
    10441 aaccggcaga cccggtcctg tacttatcga cattcccgtt gatattcagg aaaatgaaat
    10501 tgaaagtttt gaatatcccg aaagcgtaaa cattatcggt tacaagccga acactaaggg
    10561 acatgcaatt caggttaaaa aggctgttga ggccatcaac gcaagcaagc gtcctgttat
    10621 cgtatcaggc ggcggcgtgc tgagttcggg tatcaagctt aaacttcaaa aatttgcaga
    10681 aactacgggt atccccgtta tttcaactat gatgggcatc ggtgttatgc ccagcgagca
    10741 tgagctttat ctcggaatgc tcggcactca cggcaaggct gttgccaacc gtgctcttca
    10801 cgaagccgac cttgtaatcg tatgcggtgc aagactcggt gacagagctg ttgcagctcc
    10861 cgaccagatg agtgaaaaca caaaggtaat tcacattgac attgaccctg ctgaaatcgg
    10921 taagaatgtt aaaacagaaa ttccgattgt aggcgatatg aaaaatgtca tcaatatgct
    10981 gcttgacagc atcggcgatt acaaggttac aacaatgtgg agcgaaaccg taaagaactg
    11041 gaaaaaagac ctttaccgtg agcctcccgt ttttgacggc tttgttgagc cgagaacact
    11101 tgtcggtcat ctcagtgcaa tgttccgctc aaaggcaatt cttgttgccg atgtaggaca
    11161 aaatcaaatc tggtgtgcaa acaacttccg tattcgtgag ggcagatttc tcacaacagg
    11221 cggtatgggt acaatgggtt actcaattcc cgctgcaatc ggtgcaaagt ttgcaagacc
    11281 cgaccgtgat gttattgtaa tctgcggtga cggcagtttt cagatggggc ttaatgagct
    11341 tgcgactatt gcaggcaatc agctcggaat taaaatcatc attatgaaaa acgcacgact
    11401 cggaatggtt cgtgaacttc aggacaaaca ctacggcggc agacactccg caacaattct
    11461 caacggtgat cccgacttct tgaagattgc cgatgcttac ggcattgacc atgcagaggc
    11521 tcattcaaac aaggaagccg aaaacatcat caagggtatt gttgattcgg aaaaaccgtt
    11581 cattcttgtt tgcgatgttc accccgacac tccgtcaatt taatgaggtg ataaaatgca
    11641 gtatacatta tcaatacttg ttgaaaatca ggcgggcgtt ctttcaaaaa tttcgggact
    11701 tttctctcgc cgaggtttta acatcgactc actcgcagta ggtgttactc aggacccgtc
    11761 ggtttcccga atcacaatcg ttgcaaacgg tgacgagtac attgttgaac agcttgaaaa
    11821 acagctcaac aaactcattc ccgttattaa ggtaaaaagg cttaacgagg gcgaatttat
    11881 cagccgtgag cttgtattaa tcaaggttca ctgcgccgcc tcaaaaagag ccgaaattgt
    11941 caaaacggtt gaaattatgc aagcaaaaat cgttgatgta tccccttcgt cagttaccgt
    12001 tgagtactgc gaatgtgcaa gccgcatcaa cacgcttgtt gacttactca agccttatgg
    12061 tatccgtgag attgtaagaa caggtactgt tgccattgac agaggcacag cttcggtttc
    12121 cgtttaatct tacagttagc atatatttta atttatatgc cgcgtttgcg gtaaggagga
    12181 ctttaatatg aaagactaca caaaaaacat gacagcacca atctactatc agtcagattg
    12241 caaccttgac cttctcaagg gtaagaaaat tgctattatc ggttacggca gccagggtca
    12301 tgcacacgct ctcaacctca aggattcagg ttgcgatgta atcatcggtc tttacaaagg
    12361 cagcaagagc tgggcaaagg ctgaggcaca gggctttaag gtatatacat cagcagaggc
    12421 tgcaaagcag gctgacatca ttatgattct tatcaacgat gaaaagcagg cagctcttta
    12481 caagaacgac atcgagccaa acctcgaagc aggcaatatg cttatgtttg ctcacggctt
    12541 taacattcac ttcggttgca tcaagcctcc aaaggatgtt gatgttacaa tggtagctcc
    12601 taagggacct ggtcacacag ttcgttcaga gtatcaggtt ggtaagggtg taccttgcct
    12661 cgttgctgtt gagcaggacg ctacaggtca ggctaaggat ctcgcacttg catatgcact
    12721 cggtatcggc ggtgcaagag ccggcgttct tgaaacaaca ttcagaacag aaacagaaac
    12781 agacctcttc ggtgagcagg ctgttctttg cggcggtgtt tgcgcactta tgcaggcagg
    12841 ttttgaaaca ctttgcgatg ccggttacga cccaagaaac gcttactttg agtgtatcca
    12901 tgagatgaag ctcatcgttg accttatcta tcagtcaggt tttgcaggca tgagatattc
    12961 aatctctaac acagctgagt acggtgacta catcacaggt ccaaagatca tcacagagga
    13021 tactaagaag gctatgagaa aggttctttc tgacattcag gacggtacat ttgctaagga
    13081 cttcctcctt gacatgagcg atgccggttc acaggttcac ttcaaggcta tgagaaagat
    13141 cgctgccgaa gctcctgccg aagtattcgg taaggaagtt agaaagctct acagctggtc
    13201 tgacgaagat aagctcatca acaactaatg ttttttagtt cgtgaagtta gtttgatata
    13261 ttcaagcttc tgtcacccga gcattacata gtacgaattt agggtagctt gattttcaag
    13321 ctaccctttt tgcgagtacc tcgcccgcag ttcgtgtagg tagtttgtga taatttacaa
    13381 ctacttgttc ccaagcatta catagtacag attaacggtt cagtcaattt ggctgaaccg
    13441 ttttttgttg ttcaataaaa gggttcagct ttttacagct gaaccctttt gcagttaaaa
    13501 cttattaatt tttaaatatt caatacttct cataggagaa agaattataa gcgtcaagca
    13561 aagactgctt attctcagct gtagtattct cactccatac gctgttatca ccataacctg
    13621 ttgcaataaa ttcggtaaac atatgtgcat ttacgcaatt attaaactgt ttaaggttaa
    13681 tttcgttata ttttgcccgt gaaatatttt tgtcattacc gtcaaaataa ttataataaa
    13741 tattattatt tgattcttcg cctacgcctc ttgccgaata catatttgca aaaagattct
    13801 ctccgtcgta tgtgattatt gaattacccg accaatagta accatcatct acatttaaag
    13861 atatctttag gtcgtgaacc tcatactttt tggcagtttt attatagtat atcgcaaaac
    13921 cgtcgttaac atttcccact ctttttaact taccgtcttc aaatttgtaa acaacggaat
    13981 ggaaactata ctcattggaa tcagcctttt gtgcaacaag ctccggaact ccgtcaaagt
    14041 cgaaatccaa aaacataaca cctgacaaat tgtgattact tcccaagctt ggcatccatt
    14101 cactctgatg attcatcata taattgatat aagcgtccct tgttttatcg gatgtcttat
    14161 atctgtatgt tacaccggtt gggttaaaca tcgtagtaaa ctttttaccg tcttttgaaa
    14221 cacctcttac cgtataagtg ttactgccgg actttgcacc cttgtgaaca taatagttgt
    14281 cataagtttc tgctatcctc ttccaagaac cgttttcttt aatataaaca cggaactttg
    14341 gcgcatctcc cgtccaatgc atttcaacac cgttgtttac tgcaccaatg ctgtaaattt
    14401 cgggacaatc ctgatgattg ccaataggcg taccctttga atcgtagccg cttgtaaaac
    14461 tcttggcatc cttgctgata caacgaaccg tgtaataaat atcgtcaacg cttaaatcaa
    14521 attcctttga aacaacattc atatcaagca tagtcgtgcc tgttgtgtcg gcaagctttg
    14581 tccaaccgtt cctgtccttg tagtacacac gatatttttc agcacctgcg accttgttcc
    14641 atgtcagctt tacgccgtca tatgtaacct caagttttga aattttcgga gtggcgacat
    14701 actttaccga cttgcctgtc gggttataac cgcttgtgaa tttctttgcg tcggatgtaa
    14761 tacatctaac cgtataggtg taatttctgc ccgatgaaac atccttgtcg atatatgagg
    14821 ttgaagttgt atcaaccatt cgtgtccagc ctttactgcc cttgtagtaa actctgtatt
    14881 tagtcgcacc gcttactttg ccccaagaga ttttcacacc
//
