LOCUS       c00022_gnlPro..         8853 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PKAANBCB_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 06:33:06
            Original ID  :: gnl|Prokka|PKAANBCB_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8853
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8853
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3688:6916]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3689..6916
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..8853
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8853
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..2057
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="CAGKIEAKIAETDGFEDVSFNFATKLLNFKSEKQNPVSEIQAICD
                     SIEDGVTVVDKTPKNDITTKAEPEITKKKISHDTIFLAISIVLAVVSEILHLTLDGVTA
                     VHYVVLAACFVATLLSGYKVFIKGAKNILKLRIDETTLMSVAVIAAFCLGDFVEAAMVT
                     ILFSIGEIFEDRAVDASRRDIEKLANIRPDTATIIVDGAEQVVPAESVEIGSIIEVKPY
                     ERVPLDGIIIKGKTTLDTSALTGESLPVDAGEGSEVLSGAINGSNLITVKTTKHFGDST
                     ATRILQLVEDAAAQKGNSEKLISRFASVYTPVVVLIAVAIAVIPPLCGLGAFSEWLYRA
                     LVCLVASCPCAIVISVPLSYYSGIGAASEVGVLIKGGKYIEALAKADTFVFDKTGTLTS
                     GKLSVNKVNTVGSYSADEVLALAAASEKYSAHPIASAIREKANGLELPELSDYSESAGH
                     GTSAVYNGKTIQCGGSKILSDEQKKIANKDDSVFVIYDGQLIGSLNVSDTVRPEAKEVI
                     SQLKGLGVKNTVMLTGDRQQPAENVKNELGLSECHAELLPAQKLELFKGLKSKSKGACF
                     VGDGINDAPVLSASDCGIAMGFGSEAAIEASDSVLASGTLKQLPKAIKIARSVINTVKG
                     NIIFALSIKALVIILAAFGLAQIWMSVIADTGVSVVCVLIAARLLKKKY"
     CDS             2250..3491
                     /locus_tag="ctg22_2"
                     /transl_table=11
                     /translation="MNLKKIFLLLVTALFLLSLYGCNTSSSSNNSTEQTTVTDTDDSSL
                     DTDTDSETEFNYDLEIYYNDKKIDNLNLFDAFMPTEDGLIYSKINETSPNEIEYYRYYL
                     DKKSSIKLGSIKDWTMQINDKAYVNNHLCFMASTGDITDEENRTLEFIDIDLNKNKMTT
                     VFSDKGGFPYDTVTGADNLVIITKVLNNGTSLELYDTETQKFKQLKYLEFDDKNCVGKT
                     IRKVSIDDKTKTICLLVLDCVSETDVSLKIETYDYDMNFLKSYDISNISDDSNELIQGV
                     QFFDFRNNHLIYQNFSMTRCIGYIGNKKLQKSDMIDNIDDTYSMAQTPQKGYNTVLSFK
                     DVDLERNIYLFNTIDKTMKKTKFKPEEENYYIGSMSRTGKDNLMIITTPDNTDGKSNLN
                     PKLYFTKLSDLNFQ"
     CDS             3689..5311
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-43, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             5324..5815
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="ALS_ss_C (E-value: 8.1e-31, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             5876..6916
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_5"
                     /sec_met_domain="IlvN (E-value: 3.7e-84, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.9e-61, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(7325..8851)
                     /locus_tag="ctg22_6"
                     /transl_table=11
                     /translation="YTYTVRCISADGKSFTSGYDSKGTTVKYVAAPEISKLESVNGGVK
                     ISWGKVSGATKYRVYYKGSKGWTKMVDTTSTSYIDKDVSSGRNYTYTVRCITSDAKKFT
                     SGYNPTGKSVKYVATPKISKLEVTYDGVKLTWNKVAGAEKYRVYYKDRNGWTKLADTTG
                     TTMLDMNVVSKEFDLSIDDIYYTVRCISKDAKSFTSGYDSKGTPIGDHQDCPEIYSIGA
                     VNNGVEMHWTGDAPKFRVYIKEKGSWKKIAETYDNYYVHKGAKSGSNTYTVRGVSKDGK
                     KFTTMFNPTGVTYRYKTSDKTRDAYINYMMNHTDEWMPSLGSNHNLSGVMFLDFDFDGV
                     PELVAQKADSNEYSFHSVVYKFEDGKLKRVGNVNDGFAIYYNKTAKKYEVHDLKISLNV
                     DDGYYWSGNSIITYDGENLFANMYSARGVGEESNNNIYYRYFDGNDKNISRAKYNEINL
                     KQFNNCVNAHMFTKFIATGYGDNSVWGENTTAENKQSLLDAYNSFSYEKY"
ORIGIN
        1 attgtgcagg caagattgag gctaaaattg cagaaacaga cggctttgag gatgtgagct
       61 tcaattttgc gacaaaactt ctcaacttca aaagcgaaaa gcagaatcct gtttccgaaa
      121 ttcaggcaat ctgcgacagc attgaggacg gtgtaactgt tgttgacaaa actccgaaaa
      181 atgatatcac aacaaaggca gaacccgaaa tcactaaaaa gaaaatcagc catgacacaa
      241 tcttccttgc aatttcaatt gtacttgctg tagtgtccga aattctccac cttacacttg
      301 acggtgttac ggctgttcat tatgttgtac tcgcagcgtg ttttgttgca acacttcttt
      361 cgggttacaa ggtatttatc aagggtgcaa aaaacattct aaagctgagg attgacgaaa
      421 caacgcttat gtctgttgcg gtaattgcgg cattctgtct tggagatttt gttgaggcgg
      481 caatggtaac aatcctcttt tctatcggtg aaatttttga ggatcgagca gttgacgcat
      541 cccgccgtga cattgaaaag cttgcaaaca ttcgtcccga tacagcaaca attattgttg
      601 acggtgcgga acaggttgtt cctgccgaaa gcgttgaaat cggaagtatc attgaagtca
      661 agccatacga aagagttccg cttgacggca ttattatcaa aggtaaaacg actctcgaca
      721 catcggctct cacaggcgaa agccttcctg ttgatgcagg cgagggcagt gaggtactca
      781 gcggcgcaat caacggcagt aaccttatta ccgtcaaaac cacaaaacat ttcggcgaca
      841 gtaccgcaac aagaattctt cagcttgttg aagatgccgc cgctcaaaag ggcaacagcg
      901 aaaagcttat ttcaagattt gcctctgttt acacaccggt tgttgtactc attgcagttg
      961 caatcgcagt aatccctccg ctttgcggac tcggagcatt cagcgaatgg ctttaccgtg
     1021 cgcttgtttg tcttgtagcg tcatgtccgt gtgctattgt tatttccgta cctctctcct
     1081 actattcggg tatcggtgcg gcatccgaag tcggtgtact catcaagggc ggaaaatata
     1141 ttgaggctct tgcaaaagca gacacattcg tattcgataa aacaggcacg ctcacaagcg
     1201 gcaagctcag cgtaaacaag gttaatactg tcggttcata cagtgccgac gaagttcttg
     1261 ctcttgccgc tgcaagcgaa aaatattccg ctcatccgat tgcctccgca atcagagaaa
     1321 aggcaaacgg tcttgaactt cccgagcttt ccgactacag cgaaagtgcc ggtcacggaa
     1381 caagcgcagt ttataacggc aaaactattc agtgcggcgg ttcaaagatt ctttcggacg
     1441 aacagaagaa gattgcaaac aaagacgatt ctgttttcgt aatttatgac ggtcagctta
     1501 tcggttcgct caatgtcagc gacacagtaa gacctgaggc aaaagaggtt atctcacagc
     1561 ttaaagggct cggtgtcaag aacacggtaa tgctcacagg cgacagacaa cagcctgccg
     1621 aaaatgttaa aaacgaactc ggactttccg aatgtcacgc agagcttctc cctgctcaaa
     1681 agcttgaact tttcaagggc ttgaaatcaa aatccaaggg tgcttgcttt gtaggcgacg
     1741 gcatcaatga tgcccctgtt ctttcggcaa gcgactgcgg tattgcaatg ggattcggca
     1801 gtgaagccgc tattgaagcg tcagactcag ttctcgcatc aggcacactc aaacagcttc
     1861 caaaggcaat taaaattgca agaagtgtta tcaacacagt caagggcaac atcatcttcg
     1921 ccctctcaat caaggctctt gtaatcatcc tcgccgcatt cggacttgca caaatctgga
     1981 tgtctgttat cgccgacaca ggcgtcagcg tagtctgcgt cctcatagcc gcaagactcc
     2041 tcaaaaagaa atattgattt ttttgcaaat catatcattt attatgataa agcaccgtga
     2101 gctttcacaa gtttcacggt gctttcattt gccaaaattt ttctaaacat aatcttatat
     2161 tatagtattt tgaaattatt gacttttata attatttaaa ttataatgtt tttgtcagcg
     2221 cttgtaactg ataaataaac ttcggagaga tgaatttgaa aaagatattt ttattattag
     2281 taaccgcttt atttttactt tcattatatg gatgtaacac ttcttcatca agcaataatt
     2341 ccactgaaca aacaaccgta acggatacag atgattcatc tcttgataca gatacagatt
     2401 ctgaaacaga atttaattac gatttggaga tttactataa cgataaaaag attgataatt
     2461 taaatctttt cgatgcattt atgccaactg aggatggact catatattca aaaatcaacg
     2521 aaacttctcc gaatgaaata gaatactaca gatactattt agacaaaaag agcagtataa
     2581 aactcggctc aataaaagac tggacaatgc aaattaacga taaagcgtat gtaaataatc
     2641 acttatgttt tatggcaagc acgggtgaca ttacagatga agaaaacaga acccttgaat
     2701 ttattgatat agaccttaat aaaaacaaaa tgactactgt cttttctgac aaaggcggtt
     2761 ttccctatga taccgttaca ggtgcagaca atcttgtcat aattacaaaa gtattaaaca
     2821 acggtacttc tttggaactg tatgacaccg aaacgcaaaa gtttaaacaa ctgaaatatt
     2881 tagagtttga tgataagaac tgtgtaggaa aaactataag aaaagtttca attgacgaca
     2941 aaacaaaaac aatctgcctc ttggttttgg actgtgtttc ggaaacagat gtttctttaa
     3001 aaatagaaac ctatgactat gatatgaatt ttcttaaaag ctacgatatc tccaatattt
     3061 cggatgattc taacgaattg attcaaggag tgcagttttt tgattttaga aacaaccacc
     3121 ttatctatca aaattttagt atgacaagat gtataggtta tatagggaac aaaaaattgc
     3181 aaaaatccga tatgattgac aacattgacg acacctactc tatggctcaa actccacaaa
     3241 aaggatataa tacagtttta tcatttaaag atgttgattt agaacgcaat atatacttat
     3301 ttaataccat tgacaaaaca atgaaaaaaa caaaattcaa acctgaagaa gaaaactact
     3361 atatcggctc aatgtcaaga actggaaaag ataatttgat gataataaca actcctgata
     3421 atacagacgg gaaaagtaat cttaatccaa aactatactt tacaaaatta agcgacttaa
     3481 attttcagta aacaggcggt aaaaatcaat taaaatccat tttgcaaatt atctgtcaaa
     3541 atcctgcaaa aaatttaatt tatgggcaat actgctcttt actttttaag gtatttattg
     3601 tataattagc ggtaaagtaa aagggtatat ttattgttac aaaacacctt ttgctcacaa
     3661 taaataagga taggagggac aaaacataat gatcagcggt gctgaaatta tggtaaaatg
     3721 tttggaagcc gagggcgttg acatagtctt tggttatccc ggtgcggcta tctgcccatt
     3781 ttacgataaa gtttacgact cgagcattac ccacattctt gttcgtcagg aacagaacgc
     3841 tgctcatgcg gcaagcggct atgcaagatg cagtaatcgt cccggtgttt gcgtggcaac
     3901 ttccggtccc ggtgcaacca acctcatcac aggcattgca accgcctata cggactctat
     3961 tccgattgtt gccattacag gtcaggttcg ttccgacctt ctcggcagag atgtctttca
     4021 ggaagctgac atcacgggag cttgtgaacc gtttgtaaag cacagttatc tcgtcagcaa
     4081 aacagaagac cttccgagag ttttcaaaga ggctttccac attgcctcaa ccggcagacc
     4141 cggtcctgta cttatcgaca ttcccgttga tattcaggaa aatgaaattg aaagttttga
     4201 atatcccgaa agcgtaaaca ttatcggtta caagccgaac actaaaggac acgcaattca
     4261 ggttaaaaag gctgttgaag ccatcaacgc aagcaagcgt cctgttatcg tatcaggcgg
     4321 cggcgtgctg agttcgggta tcaagcttaa acttcaaaaa tttgcagaaa ctacgggtat
     4381 ccccgttatt tcaactatga tgggcatcgg tgttatgccc agcgagcatg agctttatct
     4441 cggaatgctc ggcactcacg gcaaggctgt tgccaaccgt gctcttcacg aagccgacct
     4501 tgtaatcgta tgcggtgcaa gactcggcga cagagctgtt gcggctcccg accagatgag
     4561 tgaaaacaca aaggtaattc acattgacat tgaccctgct gaaatcggta agaatgttaa
     4621 aacagaaatt ccgattgtag gcgatatgaa aaatgtcatc aatatgctgc ttgacagcat
     4681 cggcgattac aaggttacaa caatgtggag cgaaaccgta aagaactgga aaaaagacct
     4741 ttaccgtgag cctcccgtat ttgacggctt tgttgagccg agaacacttg tcggtcatct
     4801 cagtgcaatg ttccgctcaa aggcaattct tgttgccgat gtaggacaaa atcaaatctg
     4861 gtgtgcaaac aacttccgta ttcgtgaggg cagattcctc acaacaggcg gtatgggtac
     4921 aatgggttac tcaattcccg ctgcaatcgg tgcaaagttt gcaagacccg accgtgatgt
     4981 tattgtaatc tgcggtgacg gcagttttca gatggggctt aatgagcttg cgactattgc
     5041 aggcaatcag ctcggaatta aaatcatcat tatgaaaaac gcacgactcg gaatggttcg
     5101 tgaacttcag gacaaacact acggcggccg acactccgca acaattctca acggtgatcc
     5161 cgacttcttg aagattgccg atgcttacgg cattgaccat gcagaggctc attcaaacaa
     5221 ggaagccgaa aacatcatca agggtattgt tgattcggaa aaaccgttca ttcttgtttg
     5281 cgatgttcac cccgacactc cgtcaattta atgaggtgat aaaatgcagt atacattatc
     5341 aatacttgtt gaaaatcagg cgggcgttct ttcaaaaatt tcgggacttt tctctcgccg
     5401 aggttttaac atcgactcac tcgcagtagg tgttactcag gacccgtcgg tttcccgaat
     5461 cacaatcgtt gcaaacggtg acgagtacat tgttgaacag cttgaaaaac agctcaacaa
     5521 gctcattccc gtcatcaagg taaaaaggct taacgagggc gaatttatca gccgtgagct
     5581 tgtattaatc aaggttcact gcgccgcctc aaaaagagcc gaaattgtca aaacggttga
     5641 aattatgcag gcgaaaatcg ttgatgtatc cccttcgtca gttaccgttg agtactgcga
     5701 atgtgcaagc cgcatcaaca cgcttgttga cttactcaag ccttatggta tccgtgagat
     5761 tgtaagaaca ggtactgttg ccattgacag aggcacagct tcggtttccg tttaatctta
     5821 cagttagcat atattttaat ttatatgccg cgtttgcggt aaggaggact ttaatatgaa
     5881 agactacaca aaaaacatga cagcaccaat ctactatcag tcagattgta accttgacct
     5941 tctcaagggt aagaaaattg ctattatcgg ttacggcagc cagggtcatg cacacgctct
     6001 caacctcaag gattcaggtt gcgatgtaat catcggtctt tacaaaggca gcaagagctg
     6061 ggcaaaggct gaggcacagg gctttaaggt atatacatcg gcagaggctg caaagcaggc
     6121 tgacatcatc atgattctta tcaacgatga aaagcaggca gctctttaca agaacgacat
     6181 cgagccaaac ctcgaagcag gcaatatgct tatgttcgct cacggcttta acattcactt
     6241 cggttgcatc aagcctccaa aggatgttga tgttacaatg gtagctccta agggaccggg
     6301 tcacacagtt cgttcagagt atcaggttgg taagggtgta ccttgcctcg ttgctgttga
     6361 gcaggatgct acaggtcagg ctaaggatct cgcacttgca tatgcactcg gtatcggcgg
     6421 tgcaagagcc ggcgttcttg aaacaacatt cagaacagaa acagaaacag acctcttcgg
     6481 tgaacaggct gttctttgcg gcggtgtttg tgcacttatg caggcaggtt ttgaaacact
     6541 ttgcgatgca ggttacgacc caagaaacgc ttactttgag tgtatccatg agatgaagct
     6601 catcgttgac cttatctatc agtcaggttt tgcaggcatg agatattcaa tctctaacac
     6661 agctgagtac ggtgactaca tcacaggtcc taagatcatc acagaggata ctaagaaggc
     6721 tatgagaaag gttctttctg acattcagga cggtacattt gctaaggact tcctccttga
     6781 catgagcgat gccggttcac aggttcactt caaggctatg agaaagctcg ctgccgaagc
     6841 tcctgccgaa gtattcggta aggaagttag aaagctctac agctggtctg acgaagataa
     6901 gctcatcaac aactaatgcg agtgtctcgc acacagttcg tgaagacagt ttgatgtatt
     6961 caaacttctg tcacccgagt attacatagt acgaatttag ggtagcttga ttttcaagct
     7021 accctttttg cgagtacctc gcccgcacgg cgagccgccg tccccaattc gtgtagacag
     7081 tttgcaatgt aaaaaacata ttatgcccga gcgtagtatt gtagttgtgt tcgaaatttt
     7141 atagcacggc ttttattgtg tcaaaacata ttatcataaa cataaatttt catcaaggca
     7201 gacaaataat gctcctcact catctaaaaa tttcaatttt tcgttttcaa ctttcaataa
     7261 aaaaagggtt cagcttttta cagctgaacc cttttgcagt taaaacttat taatttttaa
     7321 ataatcaata cttctcatag gagaaagaat tataagcgtc aagcaaagac tgcttattct
     7381 cagcggtagt gttctcaccc catacgctgt tatcaccata acctgtcgca ataaatttgg
     7441 taaacatatg tgcatttacg caattattaa actgtttaag gttaatttcg ttatattttg
     7501 cccgtgaaat atttttgtca ttaccgtcaa aatatctata ataaatatta ttatttgatt
     7561 cttcgcctac gcctcttgcc gaatacatat ttgcaaaaag attctctccg tcgtatgtga
     7621 ttattgaatt acccgaccaa tagtaaccgt catctacatt taaagatatc tttaggtcgt
     7681 gaacctcata ctttttggca gttttattat agtatatcgc aaaaccgtcg ttaacatttc
     7741 ccactctttt taacttaccg tcttcaaatt tgtaaacaac ggaatggaaa ctatactcat
     7801 tggaatcagc cttttgtgca acaagctccg gaactccgtc aaagtcgaaa tccaaaaaca
     7861 taacacctga caaattgtga ttacttccca agcttggcat ccattcatca gtgtgattca
     7921 tcatataatt gatataagcg tcccttgttt tatcggatgt cttatatctg tatgttacac
     7981 cggttgggtt aaacatcgta gtaaactttt taccgtcttt tgaaacacct cttaccgtat
     8041 aagtgttact gccggacttt gcacccttgt gaacataata gttgtcataa gtttctgcta
     8101 tcttcttcca agaacccttt tctttaatat aaacacggaa ctttggcgca tctcccgtcc
     8161 aatgcatttc aacaccgttg tttactgcac caatgctgta aatttcggga caatcctgat
     8221 gatcgccaat aggcgtaccc tttgaatcgt agccgcttgt aaaactcttg gcatccttgc
     8281 tgatacaacg aaccgtgtaa taaatatcat caatgcttaa atcaaattcc tttgaaacaa
     8341 cattcatatc aagcatagtc gtgcctgttg tatcggcaag ctttgtccaa ccgtttctgt
     8401 ccttgtagta cacacgatac ttctctgcac ctgcaacctt gttccatgtc agctttacac
     8461 cgtcatatgt aacctcaagt tttgaaattt tcggtgtggc aacatacttt accgacttgc
     8521 ctgtcgggtt ataaccgctt gtaaatttct ttgcgtctga tgtaatacat cttacagtat
     8581 aagtgtaatt tctgcccgat gaaacatcct tgtcgatata tgaggttgaa gttgtatcaa
     8641 ccatttttgt ccagccttta ctgcctttgt agtaaactct gtatttagtc gcaccgctta
     8701 ctttgcccca agagattttt acaccgccgt ttacgctttc aagctttgaa atttcgggag
     8761 cagcaacata ttttacagtt gtcccctttg aatcatatcc gcttgtaaag ctctttccgt
     8821 cagcagaaat acatcttaca gtataggtgt aat
//
