LOCUS       c00035_gnlPro..        16234 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CPMAHIBI_35.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 04:15:00
            Original ID  :: gnl|Prokka|CPMAHIBI_35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3847
            Orig. end    :: 20081
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16234
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[13847:16840]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12993
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16234
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16234
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             212..1036
                     /locus_tag="ctg35_5"
                     /transl_table=11
                     /translation="MVYKIMYPPIPNMGDLLNKDMLEELFNIKVVRKDLKSCNLIAIGS
                     ALDHIMYSTYPRIRAKQKIEHFMNDNVHIWSTGFIRGNAELDLGLMFRHIHIHALRGRL
                     SLQRMENILGKKLDVPTGDGGLLAERWLGFYPEKKYRVGIIPHFKEQDHPVVKKLLDNY
                     ENSTLIDLKENPKKVVEKIGECEYIISSSLHGMIVADSFHIPNMHITLTNNMFGDGNKY
                     NDYLSAFDITHTPFDCSNGDMPTISEVKNNYRIDPDVVELKKEQLFNAFPKF"
     CDS             1060..2604
                     /locus_tag="ctg35_6"
                     /transl_table=11
                     /translation="MKKLSTSKQMAINMVAAIVSFLIGTGINFVLAPYLVKELGSETYG
                     FIGLANNFVQYATIVTSALNSMSGRFISIEYSKGNIDKASRYFSSVLVADLIIAGVLLL
                     VSSIITFNIEFILNVPENLVDSVKILFALTFATFIISVITAIFTTAAFVKNKLYINSLR
                     DIASNTLKLLLVVILFSFFPAKVYFLAMASLASGIFLLLTNIKVKNKILPEVKMNFNLF
                     SFKLVKVLISAGIWSSIGYLSTALNRGLDLLICNLTLGAGLMGLLSIANTVPHCIDNLI
                     TTIANIFTPRFTILYAKDNTDLLVEETKFSSKIMSFLMTAPLAGFIAFGNKFYTLWQPT
                     KSPDEITIIQILSVLVCISYLFTCHTRTLSSLFTVCNKLKASVLISLVCGVLTVIIVLL
                     LIHFTPLGVYAIAGVSSVFIGLKAIVFVPLYAAHILKIKLTTYYRSIFRGWFCFAVVIT
                     MFIFINSFVHANSWMSFLLLCAASGLAGYAVSVPLIFSRKELVLIKDKIKKKFKKS"
     CDS             2628..3542
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_7"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6.1e-31,
                     bitscore: 97.8, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYTFSVFTPSYNRAKTLPRLYEALKKQTYRNFEWIIVDDGSAD
                     NTKETVEKFISDRPDFNITYKYQTNKGKHIATNVAAQIAKGEFFITIDSDDSVKDDALE
                     TFINEWNKIPDEDRSKYKGISCRTCNESGKTNGCPLPSERFDCSDLDLRLKYKIDGEMW
                     GMTRLEIIRANPYPCVSGLHFYPENIYWDNIGRKYITRFIDTPLRYYINDQENSLTGNA
                     YSAHRETIFVRLHFINECWDYAKSNPKFFIKQFVGLSRDGLLNGKRFSEIKKMPDTFSK
                     RALAVIFYPMGYFLYKKQSGGSR"
     CDS             3542..4621
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MKKVGIVTFHRALNYGAVLQSYALQKTVSSLGAECEIVDYICPKI
                     TADYKPFRIYKNDLLKSFAKSCVMVRRRAKRRDAFKSFFNNYLVKSKKSYTPQNIRELK
                     NDYDLFISGSDQVWSPRCVGFDPAYFLTFADDKQKYSYAASFAVPTLPDEFIDEYKKRL
                     NGFQKFSVREPSGEKLVKELTGRTAETHLDPTLLISADEWKKIAVSKIDKPYILIFTAN
                     PAVSLVDFAIKLSKEKNLPVYCINDAPHPVSHGINYIVAPTVEEFVGCFKNAEYVVTNS
                     FHGTAFSVIFNKNLFVEFKNKSGRNIRSEGLLKSLGINREIVDGNCRETEINWYDVNEK
                     IKNQTIISLDYLKSFVSGG"
     CDS             4797..6560
                     /locus_tag="ctg35_9"
                     /transl_table=11
                     /translation="MYSTIKSIQLLTALLKKYNINKLVLSPGGSDIPIIHSLENDDFFE
                     CHSVVDERSAVYYGIGLAQQTKSPVACICTSGTAVSNYLPGMTEAFYQDVPIVAITADK
                     DPYRLNQLMLQKTQQVNIFESVTKKSVNLPVVRGGNDRWYCERLINEALSELDHHGTGP
                     VHINIPIVENSAVYDCENLPQVRKINRISPDMPSEKWREYAERLSKYKKILVIAGQNNC
                     FSEDDRACVEKFFEKYNCLISVEHMSNLKCKGCLMTYPLSECSMQGMFGELCPDLIISF
                     GNNIASYKLKPMIKAHKEKFVHWQIDTAGRIRDFSDKLTDVFECTPQYFFNCFAENAPQ
                     NSKNDMTYYNMWNDDIKMLDYSSNLPFSNMYVAKKLAEIIPDRSVLHLAILSSTRTMQF
                     FDLKPNVKVYSNIGALGIDGCMSSFFGQASATDELAFCVVGDLSFFYDMNSAGIRGIKN
                     NARIILLNNGGGSEFHFFMGKEKIPTINQYICAEHHKGAKGWIESLGYDYYSATTKEEV
                     DNIIPTLAEESDRPIFVEIFTDMEEDAKLINRLFHDNRMKFGGMKLKMMEKAKSILSPS
                     QIQKAKKLLKK"
     CDS             6575..7759
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_10"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 1.1e-37,
                     bitscore: 119.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 3.1e-29, bitscore:
                     91.4, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAIAGTGYVGLSNAVLLSQKHEVTAVDVVESKVKLINEKKSPI
                     ADREIEEYLADKKLNLVATVDAKSAYKNADFVIISTPTNYDDERHFFDTSSVEAVIKLV
                     IECNPNAVIVIKSTIPVGYTKSVIEKYKYTKILFSPEFLREGKALYDNLYPSRIIVGVD
                     MANEELKKSAETFATALADCAIKENIDTLFMDYTEAEAVKLFANTYLAMRVSFFNELDT
                     YAEMKNLNTKSIIDGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLKANFSDVPNDIISA
                     VVTSNKTRKEFITSQIMNKNPKAVGIYRLTMKSNSDNFRQSSIQSVMELLKNNGIELII
                     YEPTLKVDLFEGFSVENDFEKFVTKSDVIVANRYSSVLDCVKEKVYTRDLFFRD"
     CDS             7775..8926
                     /locus_tag="ctg35_11"
                     /transl_table=11
                     /translation="METLIIGKPKIEKLDNRARLCSKISENGKPSYTLWFDVDAKYADY
                     LTESADAFVVALLPYAMNNSLNISAEAKMSKQLCFQLNEIFIPVLTKNSKLFNKISISA
                     KELTQENYCCKNASATGFSRGVDSFDTICSLSENSMEKLSHLTFFNVGSHRSTANYTPE
                     QSAELYENRLEIAKKSAKIFDMPLIDINSNLGEHLTLPYVKVHHYCSFSAVLCMQKFFK
                     NYYYASGYPISSFSIKQCDTGSAHYEAFTASMLSTESTDFYITGLEKTRLEKVDFISKF
                     PITYDNLNVCYYGENNCGHCEKCVRTQFELMALGKLELYKNVFDIPKFYRDKNKYMDYV
                     LKHQNKDYYAEILSLMKKKGFKLTPIQKIKKAVYAIYLKFRGN"
     CDS             complement(9238..9456)
                     /locus_tag="ctg35_12"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEEAAKEEPQAEVTADELAEEE"
     CDS             complement(10001..10654)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_13"
                     /sec_met_domain="Radical_SAM (E-value: 4.7e-27, bitscore:
                     85.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRCQFCHNPDTWKHDENTVEYTADELLNKALAYRPYWKNKGGITV
                     SGGEPLLQIDFLLDLFKKAKKQGVNTCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDI
                     KHIDNEQHKILTGQPNTNILEMARQLSDMGKPVWIRHVLVPERNDKDEYLFRLADFIRS
                     LKNVERVEVLPYHTLGVYKWKALGYDYPLEGIEPPTKERVKNAEMILNGEKTRD"
     CDS             complement(10756..12993)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_14"
                     /sec_met_domain="Gly_radical (E-value: 1.9e-41, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 5.4e-272, bitscore:
                     893.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQRNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDEDGIAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             complement(13260..13751)
                     /locus_tag="ctg35_15"
                     /transl_table=11
                     /translation="MKTDRVITAMIEYFGSDKKRIHHFLKVYSFAKTIGESENLLPDDQ
                     ELLEISAIVHDIGIKVSEEKYNSSAGKYQELEGPHEAEKLLAALGYEKTFIDKVCYLVG
                     HHHTYGNIDTLPYRILVESDFLVNLYEDDSSRSAAEQAYDKIFRTNTGKNLLKIMFLIP
                     "
     CDS             complement(13869..14405)
                     /locus_tag="ctg35_16"
                     /transl_table=11
                     /translation="MVIIMAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSP
                     TEFILGAKYFQGTRSPNEKERELYGYSQAWMHHKGRNRHHYEYWNDYNPKTKQIENVEM
                     PVKYVIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRD
                     EGEEKTFAYIRSMKK"
     CDS             14570..15757
                     /locus_tag="ctg35_17"
                     /transl_table=11
                     /translation="MKKKIFILLLCVVLIATCILCGVTGIFGNDSQNSPKPQTPDTAAT
                     ENMTFPSKVDSLTLKVGESKLIELSSEKAKSVTKWTSSDSKIVTVDDGGRVDALKEGTA
                     LISAISKDKSKSEFQVTVAKSTTKKQQSYSTCITANLDKLENNKRNTAKNLYAIKVNRT
                     ANCVTVYTYDEKGKYTIPVRAMICSTGLDNSTITGDYTIGIKSEWLSLVGDVFGRYISG
                     ISGDYLFHSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPTGTNVSI
                     YDDAENAGPLGKPDAIKITDFTNKWDPTDSNKKCPYAKATPIISGANDYTIKSGGEFYA
                     LAGVTAVDTCGNDITSNIEVFGNVVTTRKGKYKVTYSVTDVLKRTSSVTITVTVQ"
     CDS             complement(16138..16233)
                     /locus_tag="ctg35_18"
                     /transl_table=11
                     /translation="CLCTVVYYVTTLHTSAARLDEIFCLIIYVLM"
ORIGIN
        1 aatcaaagat aagtcagaat ttgcgttgtg ctgtacgctt gtgtgcgtaa cacttccaaa
       61 acttctgatt tccaccgaac catgggcaac aacatcgata tggatgctta ttacttattc
      121 gctgatatac atatgcaaga caaatccgat atttatatct cttaatcaga gcttctgctc
      181 acggcgcaaa taatacaacg gagaaaatac aatggtatat aagataatgt atcccccgat
      241 tccgaatatg ggagatcttc ttaataaaga tatgcttgaa gaactgttta acatcaaggt
      301 tgtaagaaaa gaccttaaaa gctgtaacct gattgcaatc ggttctgcac ttgaccacat
      361 aatgtactca acatatccga ggatcagagc aaagcagaaa attgagcatt ttatgaatga
      421 taatgtccac atatggagta cgggctttat ccgaggcaat gccgagcttg atttggggct
      481 gatgttcaga catatacata tacacgctct gaggggcaga ctttcattgc agagaatgga
      541 aaatattctc ggcaaaaagc ttgatgtgcc gacaggtgac ggaggacttc ttgccgaaag
      601 gtggcttgga ttttatcccg aaaaaaagta tcgtgtcgga attatcccgc actttaagga
      661 acaggatcac cctgttgtga aaaaacttct tgataactac gaaaattcaa cgcttattga
      721 cctgaaggaa aacccaaaaa aggttgtcga aaaaataggc gagtgcgaat acattatttc
      781 aagcagcctt cacggtatga ttgttgccga cagtttccac attcccaata tgcacataac
      841 ccttacaaac aatatgttcg gtgacggaaa caagtacaat gattacctct ccgcctttga
      901 cattacacac acaccctttg attgttcaaa cggcgatatg cctacaatca gcgaggtgaa
      961 aaataattac agaatcgatc cggatgttgt tgaactgaag aaagaacagc tcttcaatgc
     1021 ttttccaaaa ttttaatcag ttaaaactaa ggtcatatta tgaaaaaatt atcaacaagt
     1081 aaacaaatgg caataaatat ggttgccgcc atagtgtctt tcttgatagg aacaggaatt
     1141 aactttgttc ttgcacccta tcttgtaaag gaactcggtt ctgaaaccta cggatttatc
     1201 ggacttgcaa acaactttgt ccagtatgcc accattgtaa catctgctct caactcaatg
     1261 tcgggcagat ttatttcaat tgaatacagc aaaggaaaca ttgacaaggc atcaagatat
     1321 ttcagctcgg ttctggttgc cgacctgatt attgccggcg ttttactttt ggtttcgtca
     1381 attattacat tcaacattga atttatactg aatgttcccg aaaatcttgt tgacagcgta
     1441 aagatattgt ttgcgctcac ttttgcaaca tttataatca gcgttatcac ggcaatattt
     1501 actactgcgg catttgtaaa aaacaagctg tatatcaatt ccctccgtga tattgcgtca
     1561 aatacgctca agctcttgct tgtagtaatt ttgttctcgt tttttcccgc aaaagtatat
     1621 tttctcgcta tggcgtcact tgcaagcgga atttttcttt tgcttaccaa tatcaaagtc
     1681 aagaataaaa ttctgccgga agtaaagatg aacttcaacc ttttcagttt caagctggta
     1741 aaagttctga tttccgcagg aatttggtcg tcaatcggtt atctcagcac agctctgaac
     1801 agaggtcttg acctgttaat ctgtaacctg actctcggag cgggactcat gggacttttg
     1861 tcgattgcaa acaccgttcc gcactgcatt gataacctta ttacaaccat tgcaaatata
     1921 ttcactccca gatttacaat cctttatgca aaggacaaca cggacttact tgttgaagaa
     1981 acaaagtttt cgtcaaagat tatgagtttt ctcatgactg cacctcttgc gggatttatt
     2041 gcgtttggca acaagttcta tacattgtgg cagccgacca aatctccgga cgaaattacc
     2101 ataattcaga ttttgtcggt gcttgtatgt atttcatacc tatttacctg tcacacaaga
     2161 actctttcta gccttttcac cgtatgcaac aagctcaagg cctccgttct tatctcgctt
     2221 gtgtgcggtg ttcttacggt tattatcgtt ttactgctca tacactttac accgctcggt
     2281 gtttatgcta ttgcaggcgt cagctctgtt tttatcggtc ttaaagcgat agtatttgtt
     2341 ccgttgtacg ccgcacatat tttgaaaata aagcttacaa catattacag gtctattttc
     2401 aggggatggt tctgctttgc tgttgttatc accatgttca tctttatcaa cagctttgta
     2461 cacgcaaaca gctggatgtc attccttctt ctctgtgcag caagcggact ggcaggatat
     2521 gccgtttccg ttccgctcat tttctcaaga aaagaactcg ttcttatcaa ggataaaatt
     2581 aagaagaagt ttaagaaaag ctaaattatt atcattttga ggttgcaatg actgaatata
     2641 ctttttccgt ttttacaccg tcatataaca gggcaaaaac tctgcccaga ttatatgagg
     2701 cgctgaaaaa acagacatac agaaattttg aatggataat tgttgatgac ggttcagccg
     2761 acaacacaaa agaaacggtt gagaaattca tcagcgacag acctgacttt aacataacct
     2821 ataaatatca gaccaacaaa ggaaaacaca ttgcaacaaa tgttgcggca cagattgcaa
     2881 agggtgaatt ctttataacg attgactccg atgacagcgt aaaagacgat gcccttgaaa
     2941 catttataaa cgaatggaac aaaattcccg atgaagacag atcaaaatac aagggaattt
     3001 cgtgccgcac ctgtaacgaa agcggcaaaa caaacggttg tcctctgccg tcagaacgat
     3061 ttgactgttc cgaccttgac ctgagattga agtataaaat tgacggtgag atgtggggaa
     3121 tgacaagact tgaaataatc agagccaacc cttatccgtg tgtttcggga cttcattttt
     3181 atcccgaaaa tatctattgg gacaatatcg gaagaaaata tataacccgt tttattgaca
     3241 caccgttgcg atattacata aacgatcagg aaaattcttt gacgggtaac gcttactcgg
     3301 ctcacaggga aactattttc gtaagactcc actttataaa cgaatgttgg gattacgcaa
     3361 agagcaatcc taagttcttt atcaaacaat ttgtgggact ttcccgtgac ggcttactca
     3421 acggtaaaag attttccgaa ataaaaaaga tgcccgacac attttcaaag agggctcttg
     3481 cggtcatatt ttatcccatg ggatattttt tgtacaaaaa acaatcaggg ggaagcagat
     3541 aatgaaaaag gtaggcattg taacatttca ccgtgcattg aactacggcg ctgtgcttca
     3601 gagctatgcg ttgcaaaaaa ccgtttcatc gctcggtgcg gagtgtgaaa ttgttgacta
     3661 tatctgtccg aaaatcacag ccgactacaa accctttcgc atttataaaa acgaccttct
     3721 gaaatccttt gcaaaaagct gtgtcatggt aagaagaaga gcaaaacgca gagacgcttt
     3781 taagtcgttt ttcaataact atcttgtaaa gagtaaaaag tcgtatactc cgcaaaatat
     3841 cagagagctt aaaaacgatt atgacttgtt catttcggga agcgatcagg tatggagtcc
     3901 gagatgcgtc ggttttgatc ccgcttattt tctgacattt gccgatgaca aacagaagta
     3961 ttcatatgcg gcaagctttg ccgttccgac attgcccgat gaatttattg atgaatataa
     4021 aaaaaggctg aacggttttc agaagttctc agttcgtgaa ccgagcggag aaaagcttgt
     4081 aaaagaactc acgggcagaa ccgccgaaac tcatcttgat cctaccctgc tgatttcggc
     4141 agacgaatgg aaaaagattg ccgtttcaaa aattgacaaa ccgtatatcc tcatttttac
     4201 ggctaatccg gcagtttcgc ttgtggattt tgccattaaa ctgtcaaaag aaaagaacct
     4261 tcccgtttac tgcataaacg atgcacctca ccctgtaagt cacggtataa attatattgt
     4321 tgcacctact gttgaggaat ttgtcggctg tttcaaaaat gccgaatatg ttgttacaaa
     4381 ctcgtttcac ggaacagcgt tttctgttat tttcaacaag aatctttttg ttgaattcaa
     4441 gaacaaaagc ggaagaaaca tccgctccga aggtcttttg aaaagtcttg gaatcaaccg
     4501 tgaaattgtt gacggaaact gccgagaaac cgaaataaac tggtacgatg tgaacgaaaa
     4561 aatcaagaac cagacaataa tatctttgga ttatcttaaa tcctttgtca gcggtggtta
     4621 aaatgagtct taaaaataca ctaaaaaaag tcagacaggg cataatcaaa acctttaaag
     4681 caaaaaatgt tgttcccgtg tatgtgcaga aggagaacaa caatattctt gacggcaaaa
     4741 ccgctctgat tacaggcggt tccggaatta tcaaaaacta aagcggagga aagcgtatgt
     4801 attctacaat aaaaagcatt cagttgctca ctgcacttct gaaaaaatat aatatcaaca
     4861 aattggtgct ttctcccgga ggcagtgata ttcctataat tcattcactt gaaaatgacg
     4921 atttttttga gtgtcattcg gtcgttgacg agagaagtgc cgtgtattac ggcatcggac
     4981 ttgcacagca gacaaaatcc cccgttgcct gtatctgtac ctcgggtacg gctgtaagca
     5041 actatcttcc gggtatgaca gaggcatttt atcaggatgt tccgattgtc gcaattaccg
     5101 ctgacaaaga cccgtacaga ttaaatcagc ttatgctgca gaaaacccag caggtcaata
     5161 tttttgaatc ggttacaaaa aaatccgtta atcttcccgt tgtgcgtggc ggaaatgaca
     5221 gatggtactg cgaaagactt attaacgagg ctctttcgga gcttgaccat cacggaacag
     5281 gacctgtgca tatcaatatt ccgattgttg aaaactcggc tgtatatgat tgtgaaaatc
     5341 ttcctcaggt taggaaaatc aacagaattt ctcccgatat gccctccgag aagtggcgtg
     5401 aatatgcaga aaggctttca aaatataaga aaattcttgt cattgccggt cagaacaact
     5461 gtttctcgga agatgacaga gcgtgcgtcg agaagttctt tgagaaatac aattgcctta
     5521 tatcggttga gcatatgtca aacctcaagt gcaagggctg ccttatgacc tatcctttgt
     5581 cagaatgctc aatgcaggga atgttcggcg agttatgccc cgatcttatt atttcgttcg
     5641 gcaacaatat tgcttcatat aaactcaagc ctatgattaa ggctcacaag gaaaaatttg
     5701 ttcactggca aattgatact gcgggaagaa tcagagattt ttccgacaag ctgacagatg
     5761 tatttgaatg tacaccgcag tatttcttta actgctttgc agagaacgca ccgcagaatt
     5821 caaaaaatga tatgacatac tacaatatgt ggaatgacga tatcaaaatg cttgattatt
     5881 caagcaatct tccgttctca aatatgtatg ttgccaaaaa gcttgctgaa attattcccg
     5941 accgttctgt tctgcacctt gcaattctca gcagtacaag aactatgcag ttcttcgatt
     6001 tgaaaccgaa tgtcaaggtt tacagcaata tcggcgctct gggtattgac ggctgtatgt
     6061 cttcgttttt cggacaggca tcggcaacag acgagcttgc cttttgcgtt gtgggcgacc
     6121 tcagtttctt ctatgatatg aactccgcag gcatcagagg aatcaagaac aatgcgagaa
     6181 ttattcttct caacaacggc ggcggttcag aatttcactt ctttatgggc aaggaaaaga
     6241 ttcctacaat caatcagtac atctgcgccg aacatcacaa gggcgcaaag ggctggattg
     6301 aatcactcgg atatgactat tacagcgcaa caaccaagga agaagttgac aacattattc
     6361 ccacactcgc agaagaatcc gaccgaccga tttttgttga gattttcacc gatatggaag
     6421 aggacgcaaa gcttattaac aggctttttc atgacaacag aatgaaattt ggcggaatga
     6481 agctcaagat gatggaaaaa gcaaagtcaa ttctcagtcc gtcacagatt caaaaggcaa
     6541 aaaaattatt aaaaaagtaa tcaggtgaaa ccaaatgaaa atagcaattg ccgggacagg
     6601 gtatgtgggt ctttcaaacg ctgtacttct ttcgcagaaa cacgaggtaa ccgctgttga
     6661 tgtagttgaa agcaaggtaa agttaatcaa tgaaaagaaa tctccgattg ccgacaggga
     6721 aatcgaagaa tatcttgctg acaaaaaatt aaatttggtt gcaaccgtcg atgcaaaatc
     6781 tgcgtacaaa aatgctgatt ttgtaattat ctctactcct accaattacg atgacgaaag
     6841 acactttttt gatacatcgt ccgttgaggc tgtaattaag cttgtaattg aatgcaaccc
     6901 aaatgcggtt atagttatca aatccactat accggttgga tacacaaaaa gtgttattga
     6961 aaaatacaaa tacacaaaaa tccttttcag tcccgaattt ttgcgtgagg gcaaggctct
     7021 ctatgataac ctctatccgt caagaatcat tgtcggtgtt gatatggcaa atgaagaact
     7081 gaaaaaatct gccgagactt ttgcaacggc acttgcagac tgtgcaatta aggaaaacat
     7141 agacactctc tttatggact acacagaggc agaagcggta aagctttttg caaatacata
     7201 ccttgcaatg cgtgtcagct ttttcaacga gcttgacaca tatgccgaaa tgaagaacct
     7261 taacactaaa agtatcattg acggtgtgtg tcttgatccg agaatcggaa atcactacaa
     7321 caatccgtcc tttggctacg gcggttactg tctgccaaag gacacaaaac agctcaaggc
     7381 caatttttcg gatgttccga acgacataat cagcgctgtt gtaacatcta acaagacaag
     7441 aaaagaattt attacatcac agataatgaa taaaaatcca aaagctgtcg gaatttaccg
     7501 ccttacaatg aagtcaaatt ccgataactt cagacaaagc tcaattcaga gcgttatgga
     7561 gcttttgaaa aataacggta tcgagttaat tatctacgaa ccgacactta aagtcgattt
     7621 attcgagggc tttagcgttg aaaacgactt tgaaaagttc gtcacaaaat cggatgtaat
     7681 cgttgcaaac agatacagct ccgtccttga ctgtgtaaaa gaaaaggttt acacaagaga
     7741 tttgtttttc agagattaat ttgagggtaa aagtatggaa acattgatta tcggcaaacc
     7801 gaaaattgaa aaacttgata atcgtgccag actctgttca aaaatcagcg aaaacggaaa
     7861 gccttcctac actctctggt ttgatgttga tgcaaagtat gctgactatc tgaccgaaag
     7921 tgccgacgca ttcgttgttg cgctgttgcc gtatgcaatg aacaacagtc tgaatatttc
     7981 ggcagaagca aagatgtcga agcaactgtg ttttcagctt aatgaaattt tcattcccgt
     8041 tcttacaaaa aattcaaaat tattcaacaa aatttcgata tctgcaaaag agcttacaca
     8101 ggaaaactac tgctgcaaaa atgcatcggc aacaggattt tcgagaggtg tggattcatt
     8161 tgacacaatt tgcagtcttt ccgaaaacag catggaaaag ctgagtcatc ttaccttttt
     8221 caatgtcggc tcccacagga gtacggctaa ttacacaccc gaacaatctg ccgagctgta
     8281 cgaaaatcgt cttgaaattg caaaaaaatc cgcaaaaatc tttgatatgc cgttgattga
     8341 cattaattca aatctcggtg aacatcttac cctgccgtat gtaaaggttc atcattattg
     8401 cagcttttcg gcggtcttat gtatgcagaa atttttcaaa aactattact atgcgtcggg
     8461 atacccgata agcagttttt cgataaaaca atgcgacacc ggctcggcac actatgaggc
     8521 atttacggca agtatgctga gtaccgaaag taccgatttt tacattacag ggcttgaaaa
     8581 gactaggctt gaaaaggttg acttcatttc aaaatttccg attacatatg ataacctcaa
     8641 tgtgtgttac tacggtgaga acaactgcgg tcactgtgaa aagtgcgtca gaacgcaatt
     8701 tgagcttatg gcactcggaa aacttgaact gtataagaat gtttttgata ttccgaaatt
     8761 ttacagagac aagaacaaat atatggacta tgttctcaaa catcagaaca aggactatta
     8821 tgcagaaatt ctcagtctta tgaaaaagaa gggtttcaag cttacgccaa ttcaaaaaat
     8881 taaaaaggct gtctatgcca tttatcttaa attcagaggg aattaaggct tacggttgct
     8941 ttaaccgaca agccattgag gaggtatagc agatatcaga tgatgtctgc gtttttataa
     9001 tgcctcacgg ctgtgggttt ggcggttact tcgcacaaaa caaaaatgca tcagagcttt
     9061 tcgggcaact gatgcatttt tcttttttaa actgttttct tgaatagact gcggtggcac
     9121 accgccgaca tcattatctg ttttcaactt tcaattctta attgaaagca ccgctcgggt
     9181 atttaacttt tgcatatgca aatactgcta cccgaattgg gtgcaacaac ttgttgctta
     9241 ttcttcctca gcaagctcat cggctgtaac ttctgcctgc ggttcttcct ttgcagcctc
     9301 ctcaggctct ttttcggaaa caatatcgtc aatttcctca ataagcttct gttctgcgca
     9361 tctgtgcttt tttaaagcga gaaatgctgc tgtggcagcc gcaagtgcag agattgcacc
     9421 gatgattgtg tagaataatt ttttgttttt atccattccg gcacctcttt cagtattaat
     9481 ataaatcagc ggaaaaaccg tatttttcta cttattgcta ttttatatca tttttacaaa
     9541 tttttcaata ggcaactgat aatctttgca caaatggctg tcagtgtgtt atattctctt
     9601 tttacgctct gcaagggcaa aaagcactcc gcccgaaatt acaacaagca tcataacagc
     9661 cgttgctgtc actcctgtct gaacactgcc gtttttatca ggctgtgaag gagtgctgtc
     9721 cgatgttgcg gcactgcctg ttgccgaagt cggatttgca gagattgtac cgacagttgc
     9781 aggctcaccc gtcggagcag tctgaacagt ctgttcctga gtagcggtcg attcttccga
     9841 cggtgacgat ttctcaacaa ggacggctta aaaatctttg aatacacctt tgattcatca
     9901 attttgctga agaaaaaaca acaaaagcag aataacaaat aaaaatcaaa acaaaaacgg
     9961 cagtaccaaa aaatcggtac tgccgttgtt atataagaaa ttaatctctt gttttttcgc
    10021 cgttaagaat catttccgca ttcttaacac gctcttttgt cgggggctca atgccctcga
    10081 gaggatagtc ataaccgaga gccttccact tgtacacacc gagtgtgtga tacggaagca
    10141 cctctacacg ctcaacattc ttgagcgaac ggataaagtc ggcaagtctg aaaagatact
    10201 cgtccttatc atttctttca ggcacaagaa catgtcttat ccatacgggc ttgcccatat
    10261 cggaaagctg tcttgccatt tcaagaatat tggtgtttgg ctgtcctgta aggattttgt
    10321 gctgttcgtt gtcgatatgc tttatatcaa gcaacagcaa atccgtatat tccattagct
    10381 ctttccactt tgaatagaac ggctctttgg ttgtaaacgg gttggcgctt gtgtcaatac
    10441 aggtattaac gccctgcttt ttagccttct tgaacaaatc aagcaaaaag tcaatctgta
    10501 aaagcggctc acctccgctt actgtgatac cgcccttatt tttccaatag gggcggtatg
    10561 caagcgcttt attaagcaac tcgtcggcgg tatattccac ggtgttttca tcgtgtttcc
    10621 aggtgtcggg attgtggcag aactggcaac gcattgcgca accgctcaga aaaatcacaa
    10681 atctcacacc cggaccgtca acagagccaa aagtttctat tgagtgtaca aagcctttaa
    10741 cagcgttgtc cgacatcaca ttctgtcgtg gcaggttctg gcaataacat ccagctgctg
    10801 ctctcttgta aggtcgatga acttaacagc ataacccgat acacggattg tgaagttagc
    10861 atactcttcc ttctcaggat gctccatagc gtcaatgagt ttttctgtac cgaatacatt
    10921 tacattgagg tggtgtgcgc cctgatcaaa gtagccgtcc ataacattta cgaggttgtc
    10981 aacacgctcg tcatcgttgt gtccgagagc acccgggttg attgtctgag tatttgaaat
    11041 accgtcaaga gcgtactcgt aaggaagctt agcaacagag ttaagtgaag caagaagacc
    11101 gttctgctct gcaccgtagc ttgggttagc accaggtgaa agtggttcgc ctgcttttct
    11161 gccgtcagga agtgaacctg tagccttacc gtaaacaaca tttgatgtga ttgtaaggat
    11221 agaagttgta ggctctgaat ctctgtatgt gtggcaatac ttgagcttag ccatgaatgt
    11281 cttgagaaga tcaacggcaa tcttatctgc tctctcgtca ttgttaccgt atcttgggaa
    11341 gtcgccctct gtttcaaagt caacagcaat gccgtcctcg tcacggataa ccttaacctt
    11401 agcgtactta atagcgctga gtgagtcaac aacatgtgag aagcctgcaa tacctgttgc
    11461 aaatgttctt cttacatctg tatcgataag agccatttct gctgcctcat agtagtactt
    11521 atcatgcatg tagtgaatca tgttaagtgt gcctacatag aggtgagcaa gccaatccat
    11581 cattgtgtca tacttcttga taacttcgtc ataatcaagg tactctgatg tgataggtgt
    11641 atattcagga ccaacctgca tctttgtctt ttcatcaata ccgccgttga tagcgtagag
    11701 aaggcactta gcaaggttag ctcttgcgcc gaagaactgg atttccttac ctgtctgtgt
    11761 tgcggatacg cagcagcaga ttgagtaatc atcgccccat acaggacgca ttacatcatc
    11821 attctcgtac tgaattgagc ttgttgtaac tgaaatatga gcagcatact tcttgaagtt
    11881 ctccggaagt cttgaagaat aaagaactgt gaggtttggc tcaggtgaag gtcccatatt
    11941 ctcaagtgtg tggaggaaac ggtagtcgtt ctttgtaacc attgaacggc cgtcaatgcc
    12001 aagacctgca acttcgagtg tagcccatac agggtcgccc gagaagagct ggttgtaaga
    12061 ctcaattctt gcaaacttaa ccatacggca cttcataaca aagtggtcaa caagttcctg
    12121 agcctgtgat tctgtaagtg taccgttctc aaggtcacgc tcgatgtaga tgtcgaggaa
    12181 tgttgataca cgaccaacgc tcattgcagc gccgttctga gtcttgatag cagcaagata
    12241 gccgaaatag agccactgaa ctgcttctgc ggcattctta gcaggctgtg aaatatcaaa
    12301 gccgtaagaa agtgccattt ccttcatatc gttaagagca cgaatctgat cagcgatttc
    12361 ttcacgaagc tggaagtcgc ctcttctcat accctgacgg tttgtttctg caaagtcctc
    12421 tttcttgcct tcgataagac ggtcaatacc gtaaagagca actcttctgt agtcaccgac
    12481 gattctgcct ctgccgtatg tgtcgggaag acctgtaaga atcttgttgt gacgggcaag
    12541 cttcatctcg ggagtgtaga tatcgaatac accctggttg tgagtcttgt gatattttgt
    12601 aaagatttcg tggagtttag ggcttggagt gtagccatac atctggcatg actgctcagc
    12661 cattttgata ccgccgtaag gcataaatgc acgcttgaga ggcttgtctg tctgaagacc
    12721 tacaaccttt tcaaggtctt tatcaagata tgcagcgccg taagctgtga tgccgcttac
    12781 aacctcagtt tccatatcaa gaacgccgcc cttggctctt tcttccttct ggagttcctt
    12841 gagctcgccc cagagcttgt ctgtagcttc tgtaggacct tcaaggaaag actggtcgcc
    12901 gtcataaggt gtgtagtttc tctgaatgaa gtctctgaca tcaatgtcgg actcccattt
    12961 gccacctgca aaatttgtcc attcttctct cattactgta aaacctccga taatgataat
    13021 taatactgaa ttttgtatat gacacaaaaa aatgccgact caattccaag cagacgcccg
    13081 gtaaggtcag ctccttgaaa aaatcgtcat acatccttgt attctgtcat ttattcactt
    13141 ttataatcat ataaccaaca ccattaaaat aacacttttt aagggcgttg tcaagcattt
    13201 tgggatactt tttacaccac tttttcacgc tcaaaacact atggtaaatg agtacaattt
    13261 tagggtatga ggaacattat tttcagcaga ttttttcctg tatttgtgcg gaatattttg
    13321 tcatatgcct gctctgctgc actgcggctt gaatcgtcct cataaaggtt cacaaggaag
    13381 tctgactcta ccaaaattcg gtacggcaaa gtatcaatat ttccataggt gtgatggtgt
    13441 cccacaaggt aacaaacttt gtcaataaat gttttttcgt aaccgagagc ggcaagcaac
    13501 ttttcagcct cgtgaggacc ttcaagttcc tgatactttc ctgcagacga attgtacttt
    13561 tcttcgctca cctttatgcc gatgtcgtga acgattgcgg agatttcaag aagctcctga
    13621 tcgtcgggca aaagattttc actttcaccg attgtctttg cgaatgaata aaccttgaga
    13681 aaatggtgaa tccttttctt gtcacttcca aaatattcaa tcatagcagt tataaccctg
    13741 tcggttttca tattatcact ccttacggcg agccgccgta ccctattcgt gtagatagtt
    13801 tttgtttgtg caattctgta ggggtagcct tgcgactata tttcagacgg gaggattcgc
    13861 acaaacaatc actttttcat acttcttata tatgcaaagg tcttttcttc accctcatct
    13921 ctcagcataa ccaataattt ttcaagcaaa gcctcggtgt tggggtgcat acggtgtttg
    13981 cctctgattc tgcaaaaata tgtaaacgga gcgccgtccg tgtaattttt gccgttgtag
    14041 attttgcttg cggcaactcg gtcgcagaac atttcgataa catattttac aggcatttca
    14101 acattttcaa tctgctttgt ctttgggtta taatcgttcc agtattcgta atggtgacgg
    14161 tttctgccct tgtgatgcat ccacgcctgt gaatagccgt acagttctct ttccttttca
    14221 ttgggacttc tcgtgccctg gaaatacttt gcacccagaa taaattctgt aggcgaatac
    14281 tttgacaaat cgtgtattaa tccctgtctg agaattcccg cccttgcaca gttggcaatt
    14341 accttgtgcc tatgacgggt tattgttctg aaatgtttaa tcggatgtgc cataattatc
    14401 accataaatt gttagtttgg aaaatacaaa acattctccg actgacattt taccacattt
    14461 ctcgccgatt taaaatagca cttgcaagat tgtcgaaaaa aagttataat atacaaaggt
    14521 taaaattttg taaccattta atgttaaatt ctataaggat aggtaatcta tgaaaaagaa
    14581 aattttcatt cttttacttt gtgttgtcct cattgcaacc tgcatattat gcggtgtgac
    14641 gggaattttc ggaaatgatt ctcaaaattc tccaaaaccg cagacgcccg atacggcagc
    14701 aaccgaaaat atgacatttc cgagcaaggt cgattcgctc acattaaaag taggcgaatc
    14761 aaagcttatt gaactgtcat ccgaaaaagc aaaatccgtt accaaatgga caagctcgga
    14821 cagtaaaatt gttaccgttg atgacggcgg aagggttgac gctctcaaag agggtacggc
    14881 tctgatttct gccatttcaa aagacaaatc aaagtcggaa tttcaggtta cggtggcaaa
    14941 atcaaccacg aaaaaacagc aaagctactc aacctgtata acggcaaatc ttgacaagct
    15001 tgaaaacaat aagcgtaaca cggcaaaaaa cctgtacgca atcaaggtca accgcacggc
    15061 aaactgcgtg acggtttaca catatgacga aaagggcaag tacacaatcc ccgtaagggc
    15121 gatgatttgc tccacaggtc ttgacaattc gacaatcacg ggtgactaca caatcggaat
    15181 caagtccgaa tggctttccc ttgtgggcga tgttttcgga agatacatca gcggaatttc
    15241 tggcgattat cttttccact ccgttcccta ctactcaatg agcgaagaag atttggagct
    15301 tgaggagttc aacaagcttg gcgaacaggc gtcacaagga tgcgtaagac ttgcggtttc
    15361 ggatgcaaag tgggtttatg acaactgccc cacaggcaca aatgtaagca tatatgacga
    15421 cgcagaaaat gcaggccctc tcggaaaacc ggatgcaatc aaaatcaccg attttaccaa
    15481 caaatgggat ccgacagaca gcaataaaaa atgcccgtat gccaaagcaa caccaataat
    15541 cagcggtgca aacgattaca caatcaaaag cggcggcgaa ttttacgccc ttgcaggagt
    15601 aacagccgtt gacacctgcg gcaacgacat aacatcgaat atcgaagttt tcggcaatgt
    15661 agtaaccacc cgaaaaggca agtacaaggt aacatattca gtcaccgatg tgcttaaaag
    15721 aacatcaagc gtaacgatta cggtaacggt gcaataaaca tggtgcgcca ctgttctccg
    15781 agcggagctt ttaaattgaa agtggaaaat tgaaaatgta aaataaaaat gcggttggca
    15841 atgtgccacc gcatttttta tgttcgtgtg ttcgtgcaga cggttttaat agtaaattac
    15901 aaatgttgcc cgagcataac atagcaattg tttgtacata cagtagcggc ggtcagtgac
    15961 cgccatttga tttggttgca aagccaaatc aaccacacag caacatacat attttgacca
    16021 agtataacat tccaattatt tttgcaatgt atgttttagg gggaaccgtg ttcgcccgtt
    16081 cgtatgcaac gcatacgatt gcacgcaatg cgtgcaaggt tcaatacaca attataatca
    16141 catcaaaaca tatatgatta aacaaaatat ttcatcaagg cgggcggccg atgtgtgcag
    16201 tgtagtaaca tagtatacaa cagtgcaaag acat
//
