LOCUS       c00221_gnlPro..         7833 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IBALIBHL_221.
ACCESSION   c00221_gnlPro..
VERSION     c00221_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 04:16:24
            Original ID  :: gnl|Prokka|IBALIBHL_221
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7833
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7833
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1596:4824]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1597..4824
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..7833
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..7833
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..1418
                     /locus_tag="ctg221_1"
                     /transl_table=11
                     /translation="LENVNGGVKISWGKVSGATKYRVYYKGSKGWTKMVDTTSTSYIDK
                     DVSSGRNYTYTVRCITSDAKKFTSGYNPTGKSVKYVATPKISKLEVTYDGVKLTWNKVA
                     GAEKYRVYYKDRNGWTKLGDTTGTTMLDMNVVSKEFDLSVDDIYYTVRCISKDAKSFTS
                     GYDSKGKPIGDHQDCPEIYSIGAVKNGVEMHWTGDAPKFRVYIKENGSWKKIAETYDNH
                     YVHKGAKSGSNTYTVRGVSKDGKKFTTMFNPTGVTYRYKTSDKTRDAFINYMMNHTDEW
                     MPSLGSNHNLSGIMFLDFDFDGVPELVAQKSDSKEYGFHSVVYKFEDGKLKRVGNVNDG
                     FSIYYNKTAKKYEVHDLKISLNVDDGYYWSGNSIITYDGENLFANMYSSRGVVEESNNI
                     YYRYFDGNDKNISRAKYNEINLKQFNNCVNAHMFTEFIAIGYGDTSVWGENTTAENKQS
                     LLDAYNSFSYEKY"
     CDS             complement(1597..2637)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg221_2"
                     /sec_met_domain="IlvN (E-value: 2.1e-84, bitscore: 269.8,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.6e-61, bitscore: 194.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLR
                     DSGCDVIVGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKIAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(2698..3189)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg221_3"
                     /sec_met_domain="ALS_ss_C (E-value: 2e-30, bitscore: 93.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQEPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRVNTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             complement(3202..4824)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg221_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-43, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKIYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             complement(5125..7449)
                     /locus_tag="ctg221_5"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCAHCAGKIEAKIAETNGFEDVNFNFATKLLNFKS
                     ERQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLNCAHCAGKIEAKIAETDG
                     FEDVSFNFATKLLNFKSEKQNPVSEIQAICDSIEDGVTVVDKTPKNDITTKPEPEITKK
                     KINRDTIFLAISIVLAVVSEILHLTLDGVTAVHYVVLAACFVATLLSGYKVFIKGAKNI
                     LKLRIDETTLMSVAVIAAFCLGDFVEAAMVTILFSIGEIFEDRAVDASRRDIEKLANIR
                     PDTATIIVDGAEQIVPAESVEIGSIIEVKPYERVPLDGIIIKGKTTLDTSALTGESLPV
                     DAGEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDAAAQKGNSEKLISKFASV
                     YTPVVVLIAVAIAVIPPLCGLGAFSEWLYRALVCLVASCPCAIVISVPLSYYSGIGAAS
                     EVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTVGSYSADEVLALAAASEK
                     YSAHPIASAIREKANGLELPELSDYSESAGHGTSAVYNGKTIQCGGSKILSDEEKKIAN
                     KDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLKALGVKNTVMLTGDRQQPAENVKNE
                     LGLSECHAELLPAQKLELFKGLKSKSKGACFVGDGINDAPVLSASDCGIAMGFGSEAAI
                     EASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKALVIILAAFGLAQIWMSVI
                     ADTGVSVVCVLIAARLLKKKY"
     CDS             complement(7460..7777)
                     /locus_tag="ctg221_6"
                     /transl_table=11
                     /translation="MENKEKTTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALSMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
ORIGIN
        1 agcttgaaaa tgtaaacggc ggtgtgaaaa tctcttgggg caaagtaagc ggtgcgacta
       61 aatacagagt ttactacaaa ggcagtaagg gttggacaaa aatggttgat acaacttcaa
      121 cctcatatat cgacaaggat gtttcatccg gcagaaatta cacttatact gtaagatgta
      181 ttacatcaga cgcaaagaaa tttacaagcg gttataaccc gacaggcaag tcggtaaagt
      241 atgtagccac accgaaaatt tcaaaacttg aggtcacata tgacggagta aagctgacat
      301 ggaacaaggt tgcaggtgca gaaaaatacc gtgtgtacta caaggacaga aacggttgga
      361 caaagcttgg cgacacaacg ggtacaacaa tgcttgatat gaatgttgtt tcaaaggaat
      421 ttgatttaag cgttgatgat atttattaca cggttcgttg tatcagcaag gatgccaaga
      481 gttttacaag cggctacgat tcaaagggta agcccattgg cgatcatcag gattgtcccg
      541 aaatttacag cattggtgca gtaaaaaacg gtgttgaaat gcattggacg ggagatgcgc
      601 caaagttccg tgtttatatt aaagaaaacg gttcttggaa gaagatagca gaaacttatg
      661 acaaccatta tgttcacaag ggtgcaaagt ccggcagtaa cacttatacg gtaagaggtg
      721 tttcaaaaga cggtaaaaag tttactacga tgtttaaccc aaccggtgta acatacagat
      781 ataagacatc cgataaaaca agggacgctt ttatcaatta tatgatgaat catactgatg
      841 aatggatgcc aagtttggga agtaatcaca atttgtcagg tattatgttt ttggatttcg
      901 actttgacgg agttccggaa cttgttgcac aaaagtctga ttccaaagag tatggtttcc
      961 attccgttgt ttacaaattt gaagacggta agttaaaaag agtgggaaat gttaacgacg
     1021 gtttttcgat atactataat aaaactgcca aaaagtatga ggttcacgac ctaaagatat
     1081 ctttaaatgt agatgacggt tactattggt cgggtaattc aataatcaca tacgacggag
     1141 agaatctttt tgcaaatatg tattcgtcaa gaggcgtagt cgaagaatca aataatattt
     1201 attatagata ttttgacggt aatgacaaaa atatttcacg ggcaaaatat aacgaaatta
     1261 accttaaaca gtttaataat tgcgtgaatg cacatatgtt taccgaattt attgcaatag
     1321 gttatggtga taccagcgta tggggtgaga atacaacagc cgagaataag cagtctttgc
     1381 ttgacgctta taattctttc tcctatgaga agtattgatt atttaaaaat tgataagttt
     1441 taactgcaaa agggttcagc cgtaaaaagc tgaacccttt tattgcacaa caaaaaaacg
     1501 gttcagccaa attgactgaa ccgttaattc atactatgta atgctcgggt gacagaagtt
     1561 tgaatatatc aaactaactt cacgaactaa aaaacattag ttgttgatga gcttatcttc
     1621 gtcagaccag ctgtagagct ttctaacttc cttaccgaat acttcggcag gagcttcggc
     1681 agcgatcttt ctcatagcct tgaagtgaac ctgtgaaccg gcatcgctca tgtcaaggag
     1741 gaagtcctta gcaaatgtac cgtcctgaat gtcagaaaga acctttctca tagccttctt
     1801 agtatcctct gtgatgatct ttggacctgt gatgtagtca ccgtactcag ctgtgttaga
     1861 gattgaatat ctcatgcctg caaaacctga ctgatagata aggtcaacga tgagcttcat
     1921 ctcatggata cactcaaagt aagcgtttct tgggtcgtaa ccggcatcgc aaagtgtttc
     1981 aaaacctgcc tgcataagtg cgcaaacacc gccgcaaaga acagcctgct caccgaagag
     2041 gtctgtttct gtttctgttc tgaatgttgt ttcaagaacg ccggctcttg caccgccgat
     2101 accgagtgca tatgcaagtg cgagatcctt agcctgacct gtagcatcct gctcaacagc
     2161 aacgaggcaa ggtacaccct taccaacctg atactctgaa cgaactgtgt gacccggtcc
     2221 cttaggagct accattgtaa catcaacatc ctttggaggc ttgatgcaac cgaagtgaat
     2281 gttaaagccg tgagcgaaca taagcatatt gcctgcttcg aggtttggct cgatgtcgtt
     2341 cttgtaaaga gctgcctgct tttcatcgtt gataagaatc ataatgatgt cagcctgctt
     2401 tgcagcctct gccgatgtat ataccttaaa gccctgtgcc tcagcctttg cccagctctt
     2461 gctgcctttg taaagaccga cgattacatc gcaacctgaa tccctgaggt tgagagcgtg
     2521 tgcatgaccc tggctgccgt aaccgataat agcaattttc ttacccttga gaaggtcaag
     2581 gttgcaatct gactgatagt agattggtgc tgtcatgttt tttgtgtagt ctttcatatt
     2641 aaagtcctcc ttaccgcaaa cgcggcatat aaattaaaat atatgctaac tgtaagatta
     2701 aacggaaacc gaagctgtgc ctctgtcaat ggcaacagta cctgttctta caatctcacg
     2761 gataccataa ggcttgagta agtcaacaag cgtgttgacg cggcttgcac attcgcagta
     2821 ctcaacggta actgacgaag gggatacatc aacgattttc gcctgcataa tttcaaccgt
     2881 tttgacaatt tcggctcttt ttgaggcggc gcagtgaacc ttgattaaaa caagctcacg
     2941 gctgataaat tcgccctcgt taagcctttt taccttgatg acgggaatga gcttgtttag
     3001 ctgcttttca agctgttcaa caatgtactc gtcaccgttt gcaacgattg tgattcggga
     3061 aaccgacggt tcctgagtaa cacctactgc aagtgagtcg atgttaaaac ctcggcgaga
     3121 gaaaagtccc gaaatctttg aaagaacgcc cgcctgattt tcaacaagta ttgataatgt
     3181 atactgcatt ttatcacctc attaaattga cggagtgtcg gggtgaacat cgcaaacaag
     3241 aatgaacggc ttttccgaat caacaatacc cttgatgatg ttttcggctt ccttgtttga
     3301 atgagcctct gcatggtcaa tgccgtaagc atcggcaatc ttcaagaagt cgggatcacc
     3361 gttgagaatt gttgcggagt gtctgccgcc gtagtgtttg tcctgaagtt cacgaaccat
     3421 tccgagtcgt gcgtttttca taatgatgat tttaattccg agctgattgc ctgcaatagt
     3481 cgcaagctca ttaagcccca tctgaaaact gccgtcaccg cagattacaa taacatcacg
     3541 gtcgggtctt gcaaactttg caccgattgc agcgggaatt gagtaaccca ttgtacccat
     3601 accgcctgtt gtgagaaatc tgccctcacg aatacggaag ttgtttgcac accagatttg
     3661 attttgtcct acatcggcaa caagaattgc ctttgagcgg aacattgcgc tgagatgacc
     3721 gacaagtgtt ctcggctcaa caaagccgtc aaatacggga ggctcacggt aaaggtcttt
     3781 tttccagttc tttacggttt cgctccacat tgttgtaacc ttgtaatcgc cgatgctgtc
     3841 aagcagcata ttgatgacat ttttcatatc gcctacaatc ggaatttctg ttttaacatt
     3901 cttaccgatt tcagcagggt caatgtcaat gtgaattacc tttgtgtttt cactcatctg
     3961 gtcgggagcc gcaacagctc tgtcaccgag tcttgcaccg catacgatta caaggtcggc
     4021 ttcgtgaaga gcacggttgg caacagcctt gccgtgagtg ccgagcattc cgagataaag
     4081 ctcatgctcg ctgggcataa caccgatgcc catcatagtt gaaataacgg ggatacccgt
     4141 agtttctgca aatttttgaa gtttaagctt gatacccgaa ctcagcacgc cgccgcctga
     4201 tacgataaca ggacgcttgc ttgcgttgat ggcctcaaca gcctttttaa cctgaattgc
     4261 gtgtccctta gtgttcggct tgtaaccgat aatgtttacg ctttcgggat attcaaaact
     4321 ttcaatttca ttttcctgaa tatcaacggg aatgtcgata agtacaggac cgggtctgcc
     4381 ggttgaggca atatggaacg cctctttgaa aactctcgga aggtcttctg ttttgctgac
     4441 gagataactg tgctttacaa acggttcaca agctcccgtg atgtcagctt cctgaaagac
     4501 atctctgccg agaaggtcgg aacgaacctg acctgtaatg gcaacaatcg gaatagagtc
     4561 cgtataggcg gttgcaatgc ctgtgatgag gttggttgca ccgggaccgg aagttgccac
     4621 gcaaacaccg ggacgattac tgcatcttgc atagccgctt gccgcatgag cagcgttctg
     4681 ttcctgacga acaagaatgt gggtaatgct cgaatcgtaa attttatcgt aaaatgggca
     4741 gatagccgca cctggataac caaagactat atcaacgccc tcggcttcca aacattttac
     4801 cataatttca gcaccgctga tcattatgtt ttgtccctcc tatccttttt actgtgagca
     4861 aaaggtgttt tgtaacatta aatatacctt tttactttac cgctaattat acaataaata
     4921 ccttaaaaag taaagagcag tattgaccat aaattaaatt ttttgcagga ttttaaatta
     4981 ttctgtcatc gcctgaaaaa gatataataa atgattaaca acaaaagcaa aatgctgacc
     5041 ataaaagtat ctgtataaga gtaataacaa gaaaattccc gaacagtttt acctgctcgg
     5101 gaacagtaat gattgttgag aaaatcaata tttctttttg aggagtcttg cggctatgag
     5161 gacgcagacc acgctgacgc ctgtgtcggc gataacagac atccagattt gtgcaagacc
     5221 gaatgcggca aggataatta caagagcctt gattgagagg gcgaagatga tgttgccctt
     5281 gacagtgttg ataacacttc ttgcaatttt aattgccttt ggaagctgtt tgagtgtgcc
     5341 tgatgcgaga actgcgtctg acgcttcaat agctgcctca ctgccaaatc ccattgcaat
     5401 accgcagtcg cttgccgaaa gaacaggggc atcattgata ccgtcaccca caaagcaagc
     5461 acccttggat tttgatttca agcccttgaa aagttcaagc ttttgagcag ggagaagttc
     5521 tgcgtgacat tcggaaagtc cgagttcgtt tttaacattt tcggcaggct gttgtctgtc
     5581 gcctgtgagc attaccgtgt tcttgacacc gagcgcttta agctgtgaga taacctcttt
     5641 tgcctcaggt cttactgtgt cgctgacatt gagcgaaccg ataagctgac cgtcataaat
     5701 tacgaaaaca gaatcgtctt tatttgcaat cttcttctcc tcgtccgaaa gaatctttga
     5761 accgccgcac tgaatagttt tgccgttata aactgcgctt gttccgtgac cggcactttc
     5821 gctgtagtcg gaaagctcgg gaagttcaag accgtttgcc ttttctctga ttgcggaggc
     5881 aatcggatga gcggaatatt tttcgcttgc agcggcaaga gcaagaactt cgtcagcact
     5941 gtatgaaccg acagtattaa ccttgtttac gctgagcttg ccgcttgtga gcgtgcctgt
     6001 tttatcgaat acgaatgtgt ctgcttttgc aagagcctca atatattttc cgcccttgat
     6061 gagtacaccg acttcggatg ccgcgccgat acccgaatag taggagagag gtacggaaat
     6121 aacaatagca cacggacatg acgctacaag acaaacaagc gcacggtata gccactcgct
     6181 gaatgctccg agtccgcaaa gcggagggat tactgcgatt gcaactgcaa tgagtacaac
     6241 aaccggtgtg taaacagagg caaattttga aataagcttt tcgctgttgc ccttttgagc
     6301 ggcggcatct tcaacaagct gaagaatcct tgttgcggta ctgtcgccga aatgttttgt
     6361 ggttttgaca gtaataaggt tactgccgtt gattgcgccg ctgagtacct cactgccctc
     6421 gcctgcatca acaggaaggc tttcgcctgt gagagccgat gtgtcgagag ttgttttacc
     6481 tttaataata atgccgtcaa gcggaactct ttcgtatggc ttgacttcaa tgatacttcc
     6541 gatttcaacg ctttcggcag gaacaatctg ttccgcaccg tcaacaataa ttgttgctgt
     6601 atcgggacga atgtttgcaa gcttttcaat gtcacggcgg gatgcgtcaa ctgctcgatc
     6661 ctcaaaaatt tcaccgatag aaaagaggat tgttaccatt gccgcctcaa caaaatctcc
     6721 aagacagaat gccgcaatta ccgcaacaga cataagcgtt gtttcgtcaa ttctcagctt
     6781 tagaatgttt tttgcaccct tgataaatac cttgtaaccc gaaagaagtg ttgcaacaaa
     6841 acacgctgcg agtacaacat aatgaacagc cgtaacaccg tcaagtgtaa ggtggagaat
     6901 ttcggacact acagcaagta caattgaaat tgcaaggaag attgtgtcac ggttgatttt
     6961 cttttttgtg atttcgggtt ctggctttgt tgtgatatca tttttcggag ttttgtcaac
     7021 aacagttaca ccgtcctcaa tgctgtcgca gattgcctga atttcggaaa caggattctg
     7081 cttttcgctt ttgaagttga gaagttttgt cgcaaaattg aagcttacat cctcaaagcc
     7141 gtctgtttct gcaattttag cctcaatttt gcccgcacaa tgagcacaat tgagattgtc
     7201 taaagtgtag gtgtattttt tgagattggt tttcggagtt ttgtcaacaa cagttacacc
     7261 gtcctcaatg ctgtcgcaga ttgcctgaat ttcggaaaca ggattctgcc tttcgctttt
     7321 gaagttgaga agttttgtcg caaaattgaa gttcacatcc tcaaagccgt ttgtttctgc
     7381 aattttagcc tcaatcttgc ctgcacaatg agcgcaattg agattgtcaa gctgatattt
     7441 atacctcata tgttccccct tattcaagaa catggtcaag tcccatttcg atgattcgtt
     7501 tcacatggtc atcgtcaagg ctgtaataaa tctgttttcc ttcacggcga acacgcacca
     7561 gcttgttctg ccttaacaca cgcagttggt gggaaattgt gctttgctcc atgctgagag
     7621 cttcagcaat gttgagcacc gacatttcat tttccgaaat ggtgtacata atgcgaagtc
     7681 gggttgaatc accgaaaacc ttaaaaaggt ctgcaagctc aaacagcaca tcaatgtcgg
     7741 gcatttcggg agtggttgtt ttttctttgt tttccatagg cgtccccttt aattttctct
     7801 caggttaaaa gttatacttg aacatatgaa gat
//
