LOCUS       c00050_gnlPro..        15548 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JNBILIEM_50.
ACCESSION   c00050_gnlPro..
VERSION     c00050_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:51:10
            Original ID  :: gnl|Prokka|JNBILIEM_50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15548
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15548
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1908:5548]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1909..5548
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..15548
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15548
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             154..693
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_1"
                     /sec_met_domain="Isochorismatase (E-value: 1.8e-29,
                     bitscore: 94.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLLVVDVQKGIVDERLYAFEKFVSNIKKLIETAREHGVEVCYIQ
                     HDDGPGTGFSIGDDAFEVYSEFQPMPAEKRFVKTVSSAFKKESGLLEYLTAKGEKDVMV
                     CGIMTDFCINATVEAGFEHGLHMIVPAYANSTLDNEYMTGEQSYHYYNEFLWPKRYADC
                     VSMDRALALFKKAIEV"
     CDS             698..1711
                     /locus_tag="ctg50_2"
                     /transl_table=11
                     /translation="MLINFNDRHAITVSGINNCPSKAICDGDLVLFTMKKTIFLLVLVL
                     SMGIYTGCGKENTEIESSYMEEQTTPENSENDEIHLEDELNIDFTCDYSESIKEDVDDV
                     VADSTSLQEELTNMEKVTQKYTPLAEAAQTQGEMNVAAHWLYTIWDTELNNLWSRLSSS
                     ADRQTKENLLAEQRNWIDLKEEVTLLNIGSREENGSMYPLLQDSYLEEITKNRVYVLAR
                     ELAKIKGEDFAMPEVSAKYGTFVDNQETGDIYSSLITRQNWEGTDEAVISIYRQGEMEG
                     SFVDHGNGELSFTSEDGSVKGMIKIDGWNGASFKVTETYGESPFPVGEEVEFPFAF"
     CDS             complement(1909..4386)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_3"
                     /sec_met_domain="PFOR_II (E-value: 6.4e-22, bitscore: 69.7,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2.2e-55, bitscore: 179.6,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.6e-12, bitscore:
                     37.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKIMYDSGNELAAFAAKQINYHVMGYYPITPSTQIAENLDVM
                     GAEGLHDIALIAAEGEHSAAGICYGASAAGGRVFNATSANGLLYALEQFPVQSGTRMPM
                     VMNVACRTVSGPLCIKGDHSDVMYLLNTGWIILFADEPQKVYDFNLLGLKLAEAVRLPV
                     AVAFDGFFTSHQKRKCLVFENDDTVTRYIGEKLSCDNPKVSAFAGTGTCGAAGELPYAS
                     VLDLAHPVSIGSYMNEPDVINNRYQLHLAMEAARNKLPKLFTEYAALSGRELSFCGAYR
                     HEDAEVLLFVLGSSYHTAMEAVDRLRQDGVAAGVITLYVLRPFPAKELRVLCHNASTIL
                     AADRQDSYGAGGGNMSLELKAALSSLPHPPRILSRIYGLGGKDFFVEDALALFKEALSP
                     DAPAFDYYGVTAGTDAPDAADSAGTSFSGTDAVTAVSHPAASINEDMISSASGRADRTI
                     ADQASGTSGKADQSMAAPAMQPQYFKPVTKEESSPGLTTCTFDPATGKMKVSGGSVKDT
                     TAMPMRVAPGHGACPGCGIPINVNLLLKGIEGNVVLLFQTGCGMVVTTGYPKTAFRVPF
                     LHNLFQNGAATLSGVVEAFHQRQKRGEYPDGEITFVMVSGDGGMDIGMGSALGTALRGH
                     KLIIFEYDNGGYMNTGYQLSYSTPLGAKSSTSHVGKTQYGKSFFHKDTPELMAATHIPY
                     VATVAESNPADFIRKAAKAAAYSREFGTAYIKALSACPLNWNDKPNLERSVIAAAVDCC
                     YFPLYEIERGITALNYDPASSNKKIPVAEWLGMMGRTRHLLKEEYRSVTEEIQKEIDRR
                     YARLKARAEHPLL"
     CDS             complement(4445..5548)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_4"
                     /sec_met_domain="POR (E-value: 1.3e-25, bitscore: 82.2,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_7 (E-value: 2.8e-09, bitscore: 29.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.5e-08, bitscore: 24.6,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00024, bitscore: 13.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIYVKNTLSLPVTNENGSYEIRLESIGGLGANLCGKMLGELGAL
                     SLSLNSLSFSSYGSEKRGSPVKAYVRWCADDRPLRVNSPVTRPHLLGIFHGGLIGTYPV
                     LEGVTVDTKIVLNTPLSADEAADKYHISIGELYCLDALALAMESHSRINMVMLGALVRA
                     SGFIPPEAAETLCRDTIGKKYPALIEANLAGLRLGYENVKMAQVDRNLAPLPDAPADRY
                     AWGYANAPIGGVNPRIGSTVSNDLTASREGYIPLFIQEKCINCGLCDTACPDMVFQFAP
                     GTYREKNCMVNRGLDYYHCKGCLRCVEVCPTSALVPALEKDYPEKPHFLPNQHLLPDAI
                     RYQTVGANSWITSDSFTDEKRVDGGVV"
     CDS             5728..6855
                     /locus_tag="ctg50_5"
                     /transl_table=11
                     /translation="MLQKITDFIKKETVLTIATVFAVVSAFWVHPGPQYVGYIDWRVLG
                     ILLSLMLIVAGFQSNGLFDAIGSRLLAKTKNTAQLMLVLVFLCFFSSMFITNDVALLTF
                     VPFACTILQKCHQERLIVTTFVLQTLAANLGSMLTPVGNPQNLYLYSISGAGLGEFIGW
                     MAPYTLVSGVLLLLVVFVLSAGKRRISLETGALLQTSGAAGRKKNGIYLALFVLSLLSV
                     ARVLPWELMLAVVLIVLIFTDRAVFLQVDYCLLFTFISFFIFIGNMGNIEAVRSVLQSL
                     VAGRELAVGIGASQIISNVPATLLLADFTHNLKNLTIGVNLGGLGTLIASMASLISYKI
                     YAHNYNKTKGRYLLWFTIANVLFLAVLVLVYVFIS"
     CDS             6874..7815
                     /locus_tag="ctg50_6"
                     /transl_table=11
                     /translation="MGESGRRADGEYDRRADGEYDRKPDGGMDMSDKKMNMESLRGTVC
                     VLLSAVCFSTGGVLIKSIPWSSVTIQGARSIFSALVVGCYMLLRRQKFVWNRTVLFGAV
                     CNTVMAFAFVAATKLTTAANAIVLQFTEPVFVILLMWLIFRKKPGRDALFACAGVFAGI
                     LCFFYTSLDAGVMAGNLLAILSGLAYALVMMQKKFRGADFESSLLVSCALSAAIGIPFY
                     GQENEMSLHIWFFVLLLGVVQFGLSYVFLSRGLDAVSPVTASLTSTIEPILNPILVAVF
                     YGETIGATAVIGALLVVGSATVYNVRQAKNAA"
     CDS             8263..9687
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EutA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_7"
                     /sec_met_domain="EutA (E-value: 3.2e-177, bitscore: 581.8,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTEEILSAGIDIGTSTTQLVFSRMILQNTGGFGRIPQIKVVSKE
                     VIYESEIYFTPLSSREEIDGERVHEIIKKEYEKAGVCPADLATGAVIITGETSRKRNAE
                     SVVRAIADVAGEFVVATAGADLESVLAGKGAGAADLSQKTGKRVVNLDIGGGTTNICVF
                     ENGNMVDTACLDIGGRLIRVKDGRVTYMAPKLQWLCGRLEIDLAEGGTAELEKLRRLTA
                     AMAELLAEAVHLAPEAAELSYMQTNHLLADGTPPDIVMFSGGVAACFGEEEDLFRYGDI
                     GILLAQAIRKNEAFRRAAVTDARETMRATVIGAGNYSMNISGSTIEYTTKPFPLKNIPV
                     VKLLLEREEEIEKLPENMHRALQLYREDQEKDRQVALAMKGLKCPTFAQVQRIAELIAD
                     QYVRECGMGRHLILVLEEDIGKAIGQALHHRLKEKCSVICIDGISCGSGDFIDLGEPVA
                     SGNVIPVIVKTLIFNG"
     CDS             9697..10647
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EutB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_8"
                     /sec_met_domain="EutB (E-value: 6.6e-115, bitscore: 376.1,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILKTRMLGQTYEFKDVKDVLAKASEKKSGDELAGVGAESALERI
                     AAKEVLAQLTVADLTEHPVVPYEEDAVTRIIQDDIDETVYGTIKDRTIQEMREWILCDV
                     TDSGALMRASRGMTSEVIAGISKIMSNMDLILAGSKIRVTATCNTTIGTENVLASRLQP
                     NHPVDDVEGVAASTLEGLSYGIGDAVIGLNPAIDTVDSTLAIWKVLGDIRDKYEIPTQT
                     CVLSHVTTQMEALRTGQGSADLCFQSIAGSEAALSAFGINTGMLSEAEMLFREEGPAKG
                     PNVMYFESPRRRSAAISRRWNADVTVWHGTIIRFW"
     CDS             10665..11042
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EutB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_9"
                     /sec_met_domain="EutB (E-value: 2.5e-56, bitscore: 183.0,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGPEYIYDTKQLTRAALEDVFCGHLHGLPMGCDVCYTNHMPTDQN
                     DSETILTLLGTAGVHYVMGLPQADDIMLMYQSTSYHDVASIRQLLKKEPIPEFKAWLEK
                     RGIWENGHLGPTAGDPSIFFK"
     CDS             11057..11842
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EutC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_10"
                     /sec_met_domain="EutC (E-value: 4.1e-76, bitscore: 247.1,
                     seeds: 176, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKETACLRDITETDIMEYMQVEHPHNEKELWKMKHATPARIGI
                     GRCGARYTTEAQLRFLAAHAAANDAVFNEVPEEVVKELGVFEVRTRCANKNEMLLRPDW
                     GREFLPDARQKIVENCVHHPQVQIYFGDGLCSPSIRANIPDLFPTIKMGLEDKGITVGT
                     PFFVRYCRVNTARTVGPLLDAEVTCVLIGERPGLLTSESMSAYIAYHARPDMLESEYTV
                     VSNISRHGVPPVEAAAHIADLIAQILEKKKSGVEFSKAE"
     CDS             11926..13407
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_permease_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_11"
                     /sec_met_domain="AA_permease_2 (E-value: 8.9e-46, bitscore:
                     148.2, seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNEGGQLVRALGLKESISMTIGTVVGVGLFTCGSSQIGYVGSG
                     IIVITFLSLLISIWPCLIYGEMSAALPCAGGTYNYAKRGLNRVWANLAGWHYIISVVGI
                     GAGETLAFSNYFKILFGELGINIEGVDSRIIAIVLVLFFLILNFRGIEMSGKAQTGFIF
                     FFWGCAVAWFLYMIPHIHLDYFGGIAMDSLPPFKEMMYIFGLVWWCYTGFETCVSMGAE
                     TKYPQYTLPRALKVSVFLVFAVNALFQWFLVGLVPHEFYHILAVADAPYAEGLRAAGLV
                     GFPIILLCIGIAFGGDLSTINPGIAAPARYIYTMAEDGSLPKFLCKVHPKYKTPYMAVL
                     VVGIINIILIATGSINYIASVSLISLAVCYMIGCLAYLGLKKHYPDMNRPYRAPAGTVG
                     CYVTIAAYTIILIFADRIALLTAAVVTVAAIVYWALFTRKHENKIPSIEEEIGILEEPS
                     PQEKAKMDKEYRIWKAGTILVTVIALGIYIIPVLF"
     CDS             13436..14998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_12"
                     /sec_met_domain="Amidohydro_3 (E-value: 2.8e-59, bitscore:
                     193.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLYEGNILTCDKENRIAHYLLEDQGKILYCGDELPAGCVAAERV
                     STGEGALIPPFVDSHIHFASYATFHAGLNVMNAQSNEEILQMLREHVKKTKEKLVIGFG
                     ASPYSVSDGHLVRRVQLDEVCPDKPLFLVKYDGHACVVNTVLLNEVRGKVQHLRGFHED
                     TGEMNQEAFFAVSDYITASLSTVQLVAHMQKALDDLAARGIGMIHTVSGVGFARDLDVD
                     LERFFARGITNGMQMRVFMQTLDVNKAVKRKLPRIGGCFETALDGCFGSMDAALLSPYE
                     NTSDCGVLYYSDEKVTEFCKAANRAGLQIGMHAIGDKAFVQAVRAIKAALDDLPREDHR
                     HTIIHACLPTAEEIAVCERYHINLAVQTAFIDWPQEPDSYLEQILGERAGRLNPIRTFC
                     EHGLILSAGSDGPCTDPDPLLWMYKACNHSNPAESISVQQALRMCTYNGYYTTFDERER
                     GSLEAGKIADMVLLDRNPYDIPKEELASVKVKQLYLRGQEYKKGNGGGAAQILRGMIKR
                     GKC"
ORIGIN
        1 ttggaaaaaa ggaaaactaa tccccattta tcaagaaaaa gaaactttca gtttgactga
       61 ttagaaacag ggaaaggcgc ggcggacaat gtagtgatct gcggcttgta atttgtggtg
      121 ggatatagcg aaagaaaaaa ggagagatcg cacatggttt tattggttgt cgatgtacag
      181 aaaggcattg tggatgaacg cttatatgcg ttcgagaagt ttgtcagtaa tatcaagaag
      241 ctgattgaga ccgctcgaga acatggggta gaagtttgct atattcaaca cgatgatggg
      301 ccgggtactg ggttttccat cggggacgat gcgtttgagg tctattctga gtttcaaccg
      361 atgcccgctg aaaaacgatt cgtcaagacc gtaagcagtg cattcaagaa agagagtggt
      421 ctgctggagt acctgacagc aaagggcgaa aaagacgtga tggtatgtgg cattatgacc
      481 gacttctgca tcaatgctac agtagaggcc ggttttgagc atggactgca catgatcgtt
      541 cctgcctatg caaattccac gttggacaat gagtacatga ctggggagca gagctaccat
      601 tactataatg agtttctctg gccaaaacgc tatgcggatt gcgtatccat ggatagggca
      661 ttggcattat tcaaaaaagc gatagaggta tagatatatg ttgataaact ttaatgatcg
      721 gcacgctatt acagtgtctg gcataaataa ttgccccagc aaggccatct gtgatggaga
      781 tttagttttg tttactatga aaaaaacaat ctttctgctg gtactggtgt taagcatggg
      841 aatttatacc ggatgtggta aagagaatac agaaatcgaa agttcctaca tggaagaaca
      901 aactacacct gagaacagtg aaaacgatga gattcatttg gaggatgaac tgaatataga
      961 ttttacttgc gattattctg agagtattaa ggaagatgta gacgatgtag tagcggattc
     1021 cacatctctg caggaagagt tgacgaatat ggagaaggtt acacaaaagt atactccatt
     1081 agctgaggcg gcacaaacgc agggcgaaat gaatgtagcc gctcattggc tctatacgat
     1141 atgggatacg gaactgaata atctctggag cagattgagt agttcagcgg accggcagac
     1201 gaaggagaat cttctggcag agcagagaaa ctggatagat ctgaaagaag aagtgacttt
     1261 attaaatatt ggttccagag aagaaaacgg tagtatgtat ccgcttttac aggactctta
     1321 tctggaggaa attacaaaaa acagggtgta tgttcttgca agagagctgg cgaagataaa
     1381 aggggaagac tttgctatgc cggaagtttc cgcaaagtac ggaacctttg tagataatca
     1441 ggaaaccggt gatatataca gttctctgat caccagacag aattgggaag gaacagatga
     1501 agcggtgatc tctatttaca gacaggggga aatggaagga agctttgtgg atcatggaaa
     1561 tggagaactg agctttacat cagaagacgg aagtgtaaaa ggaatgatca aaatcgacgg
     1621 atggaatggc gcaagtttta aagttacgga aacatacgga gaatctcctt ttcctgtagg
     1681 agaagaggtc gaatttcctt ttgccttttg atttgtgatg ctccgtgtct ttccaggcgt
     1741 tgagcgctcc gcgggctgtg ggcacaccca cggagtgtta aagcgtggca agagacatgg
     1801 aatgaaatgg ggagcgcggc aggaagaaat tcctgcccct ttttcaatta ccggtctggc
     1861 tatgaacttc caggcacaca tcctgctgcc cggaactcct ctgtgcgcct acagaagcgg
     1921 atgctctgcg cgcgccttaa gacgggcgta gcgccggtcg atctccttct ggatctcctc
     1981 ggtcacggag cggtactcct ccttcaacag atgcctggtg cgtcccatca tgcccagcca
     2041 ttccgcgaca gggattttct tattgctcga agcaggatca taattcagcg ctgtgatgcc
     2101 acgttcgatt tcgtagagcg gaaaatagca gcagtccacg gcggcggcaa tgacgctccg
     2161 ctccagattc ggcttgtcgt tccagtttaa cggacaggcg gacagcgctt tgatataggc
     2221 agtgccaaac tccctggaat aggcggctgc ctttgccgct ttccggataa aatcggccgg
     2281 attcgattct gcgactgttg cgacataggg aatgtgggtc gcggccatca gctccggtgt
     2341 gtccttgtgg aagaaactct tgccgtactg cgtctttccg acatgggaag tagaactctt
     2401 tgcgccgagc ggtgtggagt aggagagctg gtagccggta ttcatgtagc cgccgttatc
     2461 gtactcaaaa atgatcagct tatgaccgcg cagggcggtg ccgagtgccg atcccatacc
     2521 gatatccatg ccgccgtcac cgctcaccat cacaaaggta atctcgccgt ccggatattc
     2581 cccgcgcttc tggcgctggt gaaacgcctc cacaacgccg cttagggtcg ccgcgccgtt
     2641 ctgaaacaga ttgtgcagaa atggaacgcg gaacgcggtt ttggggtagc cggttgtcac
     2701 taccatgccg cagccggtct gaaacagcag gacgacattt ccctcgatgc cctttaacag
     2761 gaggttcaca ttgatcggaa tgccgcagcc cgggcaggcg ccgtgtcccg gtgcgacgcg
     2821 catcggcatg gcggtcgtat cttttacgga gccgccggag actttcattt tcccggttgc
     2881 gggatcaaag gtgcaggtgg tgagacccgg cgaggattct tcctttgtga caggcttaaa
     2941 atactgcggc tgcatcgccg gagctgccat cgactggtca gccttgccgg aagtgcccga
     3001 agcctggtcc gctattgtgc ggtcagccct gccggaggca cttgaaatca tatcttcgtt
     3061 gatagaggct gccgggtgtg aaaccgccgt caccgcgtct gtcccggaga aagatgtccc
     3121 tgcggaatct gccgcatccg gtgcatccgt gcccgcagtg acgccgtagt aatcgaacgc
     3181 cggggcgtcc ggcgagagtg cctctttaaa gagggcaagg gcgtcctcca cgaaaaagtc
     3241 cttgccgccg agaccgtaga tccggcttaa aatgcgcggc gggtgcggca gggaagagag
     3301 agcggccttt aattcaagcg acatgttgcc gcccccggcg ccgtagctgt cctgccggtc
     3361 tgcggccaga atcgtggaag cattgtggca gagcacccga agttccttag cggggaacgg
     3421 gcgcagaacg tagagggtga tcacgcctgc cgctacgccg tcctgccgca gccggtcgac
     3481 ggcttccatg gcggtgtgat aggaggagcc gagcacaaaa agcagtacct cggcgtcctc
     3541 gtgccggtag gcaccgcaga aggaaagttc cctgccggag agggcggcat attctgtaaa
     3601 cagcttcggc agcttgtttc tcgcggcttc catggcgaga tggagctggt agcggttatt
     3661 gatgacatcc ggctcgttca tataggaacc gatggaaacc ggatgcgcga gatctaagac
     3721 gctggcgtaa ggaagctccc cggcggcgcc gcaggtgccg gtgccggcaa atgcggagac
     3781 cttcgggttg tcacaggaaa gcttttcccc gatatagcgg gtgacggtgt catcattctc
     3841 aaatacaagg cacttgcgct tctgatggct cgtaaaaaag ccgtcgaacg cgactgcgac
     3901 cgggagacgg acagcctcgg caagctttag accgagcagg ttaaaatcat agactttctg
     3961 cggttcatcg gcaaaaagaa tgatccagcc tgtgttgagc agatacatga cgtcgctgtg
     4021 atcgcctttg atgcacaaag ggccggaaac cgtgcggcat gcaacattca tgaccatcgg
     4081 catgcgtgtg ccggactgca ccggaaactg ttctaaggcg tacaaaagcc cgttggcgct
     4141 ggtggcatta aatacacggc ctccagcggc tgaggcgccg tagcagatgc cggcggcgct
     4201 gtgttctccc tcggcggcga tcagggcaat gtcgtgaagc ccctccgcgc ccatgacatc
     4261 cagattttcc gcaatctgtg tagagggcgt gatcggataa taccccatga cgtgatagtt
     4321 gatctgcttt gcggcaaatg cggcaagctc attgccgctg tcatacataa ttttttgttt
     4381 ttccatatca ttctccattc tgcagacgct atgcgccggt acgattcact ggtgctgcct
     4441 gcatttatac gacgcctccg tcgacccgct tttcgtcggt aaaagaatcg cttgtgatcc
     4501 aggaattcgc accgacggtc tgatagcgga tggcgtcggg cagcagatgc tgattcggaa
     4561 gaaaatgcgg tttttccggg taatcttttt cgagtgccgg cacgagtgcg ctggtggggc
     4621 agacttccac acagcgcagg cagcccttgc agtgatagta gtcaagcccc cggttgacca
     4681 tgcagttttt ttcgcggtag gtgccgggag caaactggaa gaccatatcc gggcatgccg
     4741 tgtcacacag tccgcagttg atacattttt cctgaataaa aaggggaatg tacccttcgc
     4801 gcgaggcggt cagatcgttg gagacggtgc ttccgatccg cggattgacg ccgccgatcg
     4861 gagcgttggc atagccccaa gcataccggt ccgccggggc gtccggcaga ggggcgaggt
     4921 tgcggtcaac ctgagccatt ttgacatttt catatcccag gcgcagaccc gcgagattgg
     4981 cttcgatgag tgcgggatat tttttcccga tcgtatcgcg gcagagcgtt tcggcagctt
     5041 ccggcgggat aaatccgctg gcgcgcacca gagcaccgag catgaccatg ttgatgcggg
     5101 aatgactttc catcgcaagt gcgagcgcat ccagacaata gagttctccg atggaaatgt
     5161 ggtacttatc tgccgcctcg tcagcggaca agggggtatt taatacgatt ttggtgtcta
     5221 cggtgacgcc ctccaagacc gggtaggtgc cgatcagtcc cccgtgaaag atgccaagca
     5281 gatgcggccg ggtcacgggg ctgttgacgc gcagcgggcg gtcatcggcg caccagcgga
     5341 catacgcctt gaccggtgaa ccgcgctttt cggagccgta gctggaaaag cttaaggaat
     5401 tgagcgaaag cgacagtgcg ccgagctccc cgagcatttt tccgcagaga ttggcgccca
     5461 gcccgccgat gctctccagg cggatctcat aggagccgtt ttcatttgtg acaggtaagg
     5521 ataatgtatt tttcacgtaa atctccattc ctgcgcgggc aaccgtgcat gggaaaatga
     5581 caggcaccgg ctgtgcgcat acagcgataa caggctatct tgtggtagta tgccgcattt
     5641 tcagaaaaaa atcctatgca agtgcaaaaa agagaagtaa aataggaaag gaatttttac
     5701 aatgaaacag aaaagatgat ggacaacatg ttgcagaaga tcacagattt tataaaaaaa
     5761 gaaacggtac tcacgatcgc cacagtcttc gctgtggtat cggcattctg ggtgcacccg
     5821 ggtccgcaat acgtgggcta cattgactgg cgcgtgctcg gcattttgct gtcgctgatg
     5881 ctgattgtgg caggatttca gagcaacgga ctgttcgatg cgatcggcag ccggcttctg
     5941 gcaaagacca aaaataccgc gcagctgatg ctggtgcttg tttttttgtg ctttttttcc
     6001 agtatgttta tcacaaacga cgtcgcactt ctgacgtttg tgccgtttgc gtgcacgatc
     6061 ctgcagaaat gccaccagga gcggctgatt gtgacaacgt ttgtgctgca gacgcttgca
     6121 gcgaatctgg ggagcatgct gacgccggtc gggaatccgc agaatctgta tctttacagc
     6181 atctccggtg ccgggctggg tgaatttatc ggatggatgg cgccgtatac gctcgtgtca
     6241 ggtgtgcttc tgctgcttgt cgtgttcgtg ctcagcgcgg gcaagcgccg gatctcgctg
     6301 gagacggggg cacttttgca gacgtccgga gcagccggca ggaagaaaaa cgggatttat
     6361 ctggcgctct ttgtgctaag cctgctttcg gtagcgcggg tgcttccgtg ggagctgatg
     6421 ctcgccgtgg tgctcattgt actcattttt acggatcgcg cggtgttttt gcaggtggat
     6481 tactgtctgc tgtttacgtt tatcagtttc ttcatcttca tcggcaatat ggggaatatc
     6541 gaggcggtac ggtctgtcct gcaaagtctt gtggcgggca gggaactggc ggtcggcatc
     6601 ggtgcgagcc agatcatcag caatgttccc gcgaccctgc ttctggcaga ttttacgcac
     6661 aatctgaaaa atcttacgat cggcgtgaat ctgggcggac tgggaacgct catcgcttcg
     6721 atggcgagcc tgatctctta taagatctac gcgcacaatt ataataagac caaggggcgg
     6781 tatctcctgt ggtttacgat cgcaaacgta ctgtttctgg cagtactcgt gctggtctat
     6841 gtttttatct cataggaagt ggcagtagca cagatgggag aatccggcag aagagcggat
     6901 ggagaatacg acagaagagc ggatggagaa tacgacagaa aaccggatgg gggaatggat
     6961 atgagtgata aaaaaatgaa tatggaaagc ctgaggggaa cagtctgcgt gctgctatcg
     7021 gcagtctgtt tcagcaccgg aggcgtttta atcaaatcga ttccgtggtc gtcggtgacg
     7081 atccagggag cgcgcagtat cttctcggcg ctggttgtgg gatgttacat gcttctgcgc
     7141 cgccagaagt ttgtgtggaa taggacggtg ctcttcggtg cggtgtgcaa tacggtgatg
     7201 gcgtttgcct ttgtggcggc gaccaagctc acgacagccg ccaacgcgat tgtactgcag
     7261 ttcacggagc cggtgtttgt cattcttctg atgtggctga tctttcgcaa aaagccgggg
     7321 cgggacgcgt tgttcgcctg cgcgggagtc tttgccggaa ttctctgctt tttttatacg
     7381 tcgctggatg ccggggtcat ggcggggaat ctgctcgcga ttctctcggg tcttgcctat
     7441 gcgcttgtga tgatgcagaa gaaattccgc ggagcggact ttgaatcgtc gcttctggta
     7501 tcctgtgcgc tgagcgcggc gatcggaatc ccgttttacg ggcaggagaa cgagatgtca
     7561 ctgcatatct ggttcttcgt gctgctgctc ggcgtggtgc agttcggtct gtcctatgtg
     7621 ttcctgtcgc ggggactgga tgcggtctct ccggtcacgg cgtcgctgac ctcgacgatc
     7681 gagcccatct taaatccgat tctggtggct gtcttttatg gggagacaat cggtgcaact
     7741 gctgtcatcg gcgccctgct ggtggtcggt tcggcgacgg tctacaatgt aaggcaggca
     7801 aaaaacgctg cctgaatccg tacaaaaagg ctggaagaag tcatacaaaa ggtacaaaaa
     7861 agacaaaaat atatgagcag ccggtaaaat atttgttaaa aaaggaaatt gctgaacaaa
     7921 aagtgtcatg ctataataac ttctaaattc agatatcaga tgacatgtgc aagggagcac
     7981 cgcggtagcg gctgctctct ttttttatgt aataggcaac ttcgttccta ttacataaaa
     8041 aagctccccg gggatcgcac tgcggcggag acggaagata tcgcaagagc gacccgccgc
     8101 aggcggagaa tcctgcaggc aggattctta tttaatgtaa taggcaatac catattgcgc
     8161 taagatgtga aagtctggct gccgtagata aaaacaaccg cgtaatcata ttatgagcgg
     8221 cagacacaga cagaaaagaa cagttttttg aggaggagaa gaatgcagac ggaagagatt
     8281 ttaagtgccg gaattgatat tggaacgtcg acgacgcagc ttgtgttcag caggatgatt
     8341 ctccagaaca caggcggatt tggcagaatt ccacagatca aggtggtgtc caaggaggtc
     8401 atctacgaga gtgagattta ttttacaccg ctgtcatccc gggaggagat tgacggggag
     8461 cgcgtgcatg agattataaa aaaggaatat gagaaggcgg gcgtttgtcc ggcagatctt
     8521 gcaaccggag ccgtcatcat cacgggggag acttcacgga aaagaaatgc cgagtcggta
     8581 gtgcgggcga tcgccgatgt ggcgggagag ttcgtcgtgg cgacagcggg agcggatctg
     8641 gagtctgttc tggcaggaaa aggtgcggga gccgcggatt tgtcccaaaa gacggggaag
     8701 cgggtagtca atctggatat cggcggcggc acgacaaata tctgcgtttt tgagaacgga
     8761 aatatggttg atacggcatg cctcgacatc ggcggcagac tgatccgcgt gaaggatggc
     8821 agggtgacct acatggcgcc caagctgcaa tggctgtgcg gcaggcttga gattgatctt
     8881 gcggagggcg gaacggcaga actggaaaag ctgcgcagac tcaccgctgc gatggcggaa
     8941 cttcttgcgg aggcagtgca tctggcgccg gaggcagcag agctttccta catgcagacc
     9001 aaccatcttc tggcggatgg cacgccgccc gatattgtga tgttctccgg tggggtggcg
     9061 gcatgcttcg gggaagagga ggatctgttc cgctatgggg acatcggaat ccttttggcg
     9121 caggcgatcc ggaagaacga agcgtttcgc cgggcggcag tgacggatgc gcgggaaacc
     9181 atgcgggcga cggtgatcgg cgcgggaaac tacagcatga acatttccgg aagtacgatt
     9241 gagtacacga cgaaaccgtt tccgttaaaa aatattccgg tggtgaagct tttgctggag
     9301 cgtgaggaag agattgaaaa actgccggaa aacatgcacc gggcgctgca gctttaccgg
     9361 gaggatcagg aaaaagaccg gcaggtggcg cttgccatga aggggttaaa gtgccctact
     9421 ttcgcacagg tacaaagaat agcagaactg attgcagacc agtatgtcag ggagtgcggc
     9481 atgggcaggc atctgatcct ggtgcttgag gaggatatcg gaaaagcaat cgggcaggcg
     9541 ctgcatcaca gactgaaaga gaagtgcagc gttatctgca tcgatggaat cagctgcggg
     9601 agcggagatt ttattgatct gggcgaaccg gttgcatcgg gtaacgtcat tcccgtgata
     9661 gtaaagacat tgatatttaa tggttaggag tagcttatga tattaaagac acggatgctg
     9721 gggcagacct atgaatttaa ggatgtaaaa gatgtgctgg caaaggcgag cgagaaaaaa
     9781 tcgggagacg agctggcagg tgtgggagcg gagagcgcct tagagcggat tgccgctaag
     9841 gaggtgctgg cgcagctgac cgtggcggat ttaacagagc atcccgtggt gccctacgag
     9901 gaggatgcgg tgacgcggat cattcaggat gatatcgatg aaacggtcta cggcacgatc
     9961 aaggacagaa cgatccagga gatgcgggag tggattctct gtgacgtcac agacagcggg
    10021 gcgctgatgc gcgcaagccg gggaatgacc agcgaagtga ttgccgggat ctccaagatc
    10081 atgagcaata tggatctgat tcttgctgga agcaagatcc gggtgacggc gacctgcaat
    10141 accacgatcg gcacagaaaa cgtgctcgcg tcgagactgc agcccaatca tccggtggat
    10201 gatgtggaag gcgtggcagc cagcacctta gaaggactca gttacggcat cggcgacgct
    10261 gtcatcgggc tgaatccggc gattgatacg gtggacagca cgcttgcaat ctggaaagtg
    10321 ctcggggaca tccgggataa atatgagatt ccgacacaga cctgtgtgct ctcacatgtg
    10381 acgacacaga tggaggcgct tagaaccggg cagggaagcg ccgatctgtg tttccagtcg
    10441 attgcgggat cggaggcggc gctctcggcg tttggcatca acaccgggat gctgtcggag
    10501 gcggagatgc tgtttcggga ggagggaccg gcaaagggac ccaacgtcat gtattttgag
    10561 agtcctcggc ggcgttcggc agcgatcagc agacgatgga atgcagatgt tacggtctgg
    10621 cacggcacta tcatccgttt ctggtgaaca cggtggtagg tttcatgggg ccggagtata
    10681 tctacgacac caagcagctc acaagggcgg cgcttgagga cgtattctgc gggcatctgc
    10741 acggactgcc gatgggctgc gacgtatgtt atacgaacca catgccgacc gatcagaacg
    10801 actcggagac gatcctgaca cttctgggaa cggcgggcgt tcactatgtg atgggactgc
    10861 cgcaggcgga tgatattatg ctgatgtatc agtccaccag ctatcacgat gtggcgagta
    10921 tccggcagct gctgaaaaag gagccgatac cggagtttaa ggcatggctt gaaaaacggg
    10981 gcatctggga aaacgggcat ctcggcccga ccgccggaga tccgtccata ttttttaaat
    11041 aggaggaacg ggatttatga gtgaaaaaga gaccgcctgc ctccgcgata ttacagagac
    11101 agacattatg gaatatatgc aggtggagca cccgcacaat gaaaaggaac tctggaagat
    11161 gaagcatgcg acgcccgcgc ggatcgggat cggacggtgc ggcgcacgct acacgaccga
    11221 ggcgcagctc cggtttctgg cggcacatgc ggcggcaaac gacgcggtgt tcaatgaagt
    11281 gccggaggaa gtggtaaagg agcttggcgt ttttgaggtg cggacaagat gcgccaataa
    11341 aaacgaaatg ctcctccgcc cggactgggg cagggagttt ttgccggatg ccagacaaaa
    11401 aattgtggaa aactgtgtcc atcatccgca ggtacagatc tatttcggcg acgggctgtg
    11461 ctcgccgtct atcagggcga acattccgga tctgtttcca accataaaaa tgggtctgga
    11521 ggataaggga attaccgtcg ggacgccgtt tttcgtgcgg tattgcagag tgaataccgc
    11581 gcggacggtc ggaccgctcc tggatgcgga ggtgacctgc gtgctcatcg gagagcgccc
    11641 gggtcttctg acgtcagaga gcatgtcggc atatatcgcc taccatgcga gaccggacat
    11701 gcttgagtcg gagtatacgg tcgtatcgaa tatcagcagg cacggtgtgc cgccggtgga
    11761 ggcagccgca catattgcgg atctgatcgc acagatcctg gaaaagaaaa aaagcggtgt
    11821 agaattttca aaagcagaat aaagacatgg ttgcgaagaa gcacaggcgg gacgtctgtg
    11881 ctctttttct ataggagcag caagacagac aaaggaggat acgttatgga gaaaaacgaa
    11941 ggaggtcagc tggtgcgtgc tctcggactg aaagagtcga tcagtatgac gataggaacg
    12001 gtagtaggag tgggactgtt tacctgtggt tcctcacaga ttggatatgt cggatcgggg
    12061 attattgtaa ttacattttt atccctgctc atttcgatct ggccctgtct gatctacggc
    12121 gagatgtcag cggcacttcc gtgtgccgga ggtacttaca attatgcgaa gcgcggactc
    12181 aaccgggtct gggcgaatct ggcaggctgg cattacatca tctccgtggt cggcatcggc
    12241 gcgggcgaga cactggcatt ttccaattat tttaaaattc tgttcggaga actcggcatc
    12301 aatatcgagg gagtggattc tcggatcatt gcgattgtgc tggttctgtt tttcctgatc
    12361 ttgaacttcc ggggaattga gatgtctgga aaagcgcaga cgggattcat tttcttcttc
    12421 tggggctgtg ccgtggcatg gttcttatat atgataccgc acattcacct ggactatttc
    12481 ggcgggatcg ccatggattc cctgccgccg tttaaggaaa tgatgtacat tttcggactg
    12541 gtatggtggt gctataccgg atttgagacc tgtgtatcga tgggtgcgga gacgaaatat
    12601 ccgcagtata cgcttccgag agcgttaaaa gtatcggtat tccttgtatt tgcagtcaac
    12661 gcgttattcc agtggtttct tgtcggactg gtgccgcacg agttttacca catccttgca
    12721 gtggcagacg caccgtatgc ggagggactc cgggctgccg gactggtggg cttcccgatc
    12781 attctgctct gcatcggcat tgcattcggc ggcgatctct ccaccatcaa tccgggaatt
    12841 gcagcaccgg cgcgctacat ctacacgatg gcggaggacg gttccctgcc gaagttcttg
    12901 tgcaaggtac atccgaagta taagacaccg tatatggcgg ttcttgtggt cggcatcatc
    12961 aatattatcc tgattgcaac agggtcaatc aattatatcg cgtcggtatc gctgatctca
    13021 ctcgcagtat gttatatgat tggctgtctg gcttaccttg gcttaaagaa acactatccg
    13081 gatatgaacc ggccgtacag ggcgccggca ggaacggtcg gatgctatgt cacgattgca
    13141 gcctacacta ttattctgat tttcgcagac cgcatagcgc ttctgacggc ggcggttgtg
    13201 actgtggcag cgattgtcta ctgggcgctt ttcaccagaa agcatgagaa taagattccg
    13261 tccattgagg aggagatcgg tatcctcgag gagccgtccc cccaggaaaa ggcaaagatg
    13321 gacaaggagt accggatctg gaaagccggc acgatccttg tgacggtgat agcacttggc
    13381 atttacatta ttccggtctt attttaaaat ttaagggatt ggaaaggagc acggtatgag
    13441 actttatgag ggtaacattt taacctgtga caaagagaac cggattgcac attatttgtt
    13501 ggaggatcag gggaaaatcc tttactgcgg ggacgagctg ccggccggct gtgtggcggc
    13561 ggagcgcgtg tccaccgggg agggggcatt gattccgccg tttgtggaca gtcatatcca
    13621 tttcgcaagt tacgcgacgt ttcatgccgg gctcaatgtc atgaatgcgc agagcaatga
    13681 ggagattctt cagatgctcc gggagcatgt gaagaaaacg aaggaaaagc tggtgatcgg
    13741 gtttggcgca tcgccgtatt ccgtgtcaga cggacatctg gtgcgcaggg tgcagctgga
    13801 tgaggtgtgt cccgacaaac cgctctttct ggtaaagtac gacggtcacg cgtgtgtcgt
    13861 caacacggtg ctgttaaacg aagtgcgcgg caaggtgcag catctgcgcg gttttcatga
    13921 ggataccggg gagatgaacc aggaggcatt tttcgccgtc tcggattata tcacagcttc
    13981 gctctctacg gtgcagctgg tggcgcacat gcagaaggcg ctggacgatc tggctgcgcg
    14041 cggcatcggc atgatccata cggtcagcgg cgtcggcttt gcgagagatc tggacgtcga
    14101 tctggagcgt ttttttgcgc gcggcatcac aaacggcatg cagatgcgcg tgtttatgca
    14161 gacgctcgat gtgaataagg cggtaaagcg gaagcttccg agaatcgggg gctgttttga
    14221 gacagcgctt gacggatgct tcggttccat ggatgcggca ctgctctcgc cgtatgaaaa
    14281 cacgtcggac tgcggcgtac tctactattc ggatgaaaaa gtgacggaat tctgtaaggc
    14341 ggcaaaccgc gccggtctgc agatcgggat gcacgcgatc ggcgataagg cgtttgtgca
    14401 ggcggtgcgt gccatcaagg cggcgcttga cgatctgccc agagaagatc acagacatac
    14461 gatcatccat gcatgtctgc cgactgcgga ggagattgcg gtctgtgagc ggtatcacat
    14521 caatctggca gtgcagacgg cgttcattga ctggccgcag gagccggaca gctatctgga
    14581 gcagatcctc ggagagcgtg cgggcaggct gaatccgatc cgcacattct gcgaacacgg
    14641 actgatttta agtgcgggat cggacggacc ctgcacagat ccggacccgc ttttatggat
    14701 gtataaggca tgcaatcaca gcaatccggc agaatccatc tccgtgcagc aggcgctgcg
    14761 catgtgtacc tacaacggat attacacgac ctttgatgag agggagcgcg gaagtctgga
    14821 agcgggaaaa atagcggaca tggtgttgct ggaccgcaat ccttacgaca tcccgaagga
    14881 ggaactggct tccgtcaaag tgaagcagct ctaccttcgg gggcaggaat ataaaaaagg
    14941 aaacggcggc ggagccgcac agattctgcg cggaatgata aagcggggaa aatgctgacc
    15001 ggcatttttc ccagttaggg tgatcttaca gatattttac atatcccttc taaattttac
    15061 acaacgcacc cgaacaattt tacaaacctc cgatatgata gaagaaataa gaagctatca
    15121 tatcggaggt ttttgtatac atggaaaaac agacactggt atgggcgcac cgcggtgcaa
    15181 gcggctacgc gcctgaaaat acactggaag catttcagaa agcggttgag atgggcgcag
    15241 acggcgtgga gctggatgtg cagctcacaa aggatggaga gctggttgtc atccacgacg
    15301 agacggttga ccgcaccagc gatggcagcg gctgggttaa ggattttaca tacgcgagaa
    15361 tttccaggtt taattacaac cggacgcata aggaagggta cgagcgggcg atgatcccga
    15421 cgctcgagga agtctatgag ctgctaaagc cgacgggact tacaatcaat gtggaattga
    15481 agaccggcgt ggtcttttat ccggagatcg aagagcgcgt gcttgacctg accgcccgta
    15541 tgggactg
//
