LOCUS       c00104_gnlPro..        12140 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JNBILIEM_104.
ACCESSION   c00104_gnlPro..
VERSION     c00104_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:51:10
            Original ID  :: gnl|Prokka|JNBILIEM_104
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12140
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12140
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7547:11831](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7548..11831
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..12140
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12140
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(3..2036)
                     /locus_tag="ctg104_1"
                     /transl_table=11
                     /translation="MKSKKNTFVSRAAVGCVTTAIFLLLCIIKGIYPFGIATLDTVDFQ
                     SQWIPAYYHVWDVLHGDGSAFFDWRVGGGNNFAGVSAQFSLFSPFNLFFLFVKRSWIEK
                     SMIVFLLIKLLAMGYGMRWFLKEQILKEERYGIYILAGSVGYAVNGYTLLYYGMGWLDV
                     AAILPLLCYFFCRMAEREGDWRLGKNTLGYIVCLTLVFLINIPQAYMMCFFLIVFAGGY
                     FFLKRQDQPLKKNGILKFGLTSLLSLGIAAVIFLPAARAMLGSYRLSSEEYRGISGYFL
                     LLRQDGMDAVWKWVILGSVAVPLLFFVISGRRKREHIWQWYLVAAMVLPVFFEAVNLIW
                     HRGTYVCFPMRYGYMLVFAVICMAAARVPDFVGDSRVRRNILYAFLGIWCVQMVALGIS
                     LIQPETHTDETDFVGDATEIGQPLAGKTDVFHKAKLADGAIDNNYPLIAESTSYSNYLH
                     LMTSEQIRMNTLLGYSQVWTRLSDTGGTLASDIMLGYRYYVASKAGSWGKDTAADSLWP
                     LAETEKFTLWENAPVGDRAFFITKADYEAYAVTEAYTENVFENQNRLSELLFHTTPIDW
                     KKETYLDDQTGAELSYRFYADGKQILYLYGKDLQQAEITVNGERLYVPDYNDLYNESYP
                     ATGNQGILSLGCFSDEDITVEIRQSVGDLGAERAVFVGIRAPQ"
     CDS             complement(2125..2442)
                     /locus_tag="ctg104_2"
                     /transl_table=11
                     /translation="MFSILATESASSAGWISMVVWLVILFAFMYFFMVRPQKKEQQKKN
                     SMLAELAVGDTILTTSGFYGTVIDIADDTVIVEFGSNKNCRIPMQKAAISAVEKPEDVT
                     E"
     CDS             complement(2547..3698)
                     /locus_tag="ctg104_3"
                     /transl_table=11
                     /translation="MYELLKQEGRAKRGVFHTVHGDIQTPVFMNVGTVAAIKGAVSTED
                     LEQIKCQVELSNTYHLHVRTGDKLIKEVGGLHKFMSWNRPILTDSGGFQVFSLAGLRKI
                     KEEGVYFHSHIDGAKIFMGPEESMQIQSNLGSTIAMAFDECPPALAERKYVEDSVARTT
                     RWLERCKNEMQRLNGLEDTVNRHQMLFGINQGAIYTDIRIDHAKRISEMDLDGYAVGGL
                     AVGETHEEMYHVLDETVPYLPVNKPTYLMGVGTPANILEGVERGIDFFDCVYPSRNGRH
                     GHVYTNQGKINLFNQKYEKDMRPIEEGCGCPTCRRYSRAYIRHLLKAKEMLGMRLCVLH
                     NLYFYNTMMEEIRDALDAGNFASYKEEKLYGMGQINREKEMAK"
     CDS             complement(3803..5128)
                     /locus_tag="ctg104_4"
                     /transl_table=11
                     /translation="MIEKYLVKKITEPVDWKVTVPGSKSMTNRALLMAVLSAGTVRVEG
                     VLFSDDSRHFLACLVALGFTVEIEEEKKCVTVTGCGGRIPRGEAVIDVGSAGTAARFLA
                     AMLGFSDGCYEIRCSAQMKRRPMAELFDLLSGAGAKITFLEEEGHLPVRITGCRYARAD
                     KTAGETPRELSLDITKSTQFLSALLLIAPMVPEGMKIHITSEKTDGSYIRITRKMMQEF
                     GVSVAFDGRDYEVPCRSSYRKETYMVEPDMSAACYFYAAAAMTGGRALVRHVHMDNTQG
                     DLRFLEVLEHMGCTADDTPEGILVTGPADGALRGITVNMNDFSDQALTLAAIAPFADAP
                     VRIEGIGHIRGQECDRIHAIQTNLTALGIRCEEEETAATIYPSSPHGGSVETYDDHRVA
                     MAFSLVGLRTDGIVIENPACCRKTFENYFTVLSELTGKTVEG"
     CDS             5253..6353
                     /locus_tag="ctg104_5"
                     /transl_table=11
                     /translation="MAGSTLGTLFKITTWGESHGKGVGVVIDGCPAGLSLCEADIQKFL
                     DRRKPGQSRYATPRKEDDAVEILSGVFEGKTTGTPISLVVFNRNQQSKDYSEIASYYRP
                     GHADYTFDQKYGFRDYRGGGRSSGRETIGRVAAGAVAVKILNELGITFMTYTKSIGPIA
                     VSSGRFDFSEVTKNPLYMPDAEAAENAENYLDACMTELNSSGGIVECIIKGMPAGIGDP
                     VFEKLNANLAKAVMSIGAVKGFEIGDGFDVAKATGKNNNDAFVLSEDGRIAKATNHAGG
                     ILGGMSDGSDIILRAAIKPTPSIAATQRTVNQSGEEISVNIKGRHDPIIVPRAVVVVES
                     MAAITIVDALFSNMSARMDALKDFYS"
     CDS             complement(6429..7286)
                     /locus_tag="ctg104_6"
                     /transl_table=11
                     /translation="MNWLNKLERKFGNWAIPNLIVWLIGAYTIGFVLYQVNPSIIGLLM
                     LSPYHILHGQVWRLITWVFMPTDTNLVYLLIMALFYYQLGTALERTWGTFRFNVYIFGG
                     MLFTVIGAFLLYGIMYLLNGGVTTEMLLIGTSFSTSYINMSIFLAFACMYPDMQVLLMF
                     IIPIKMKWMAVVYGVLIALSFFETGWAGRVAIFMSLLNFIIFFFSTRNLKRYTPHEVHR
                     RQKFKADMRRPQGYAGGAKHKCAVCGRTELDDPTLEFRFCSKCEGNYEYCQDHLFTHQH
                     IRMS"
     CDS             7548..11831
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_7"
                     /sec_met_domain="HGD-D (E-value: 8.6e-61, bitscore: 195.3,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.3e-38, bitscore:
                     121.9, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNTLHKLGIDIGSTTVKVAILDQKDHLLFSDYERHFANIQETL
                     SSLLQKAYDALGDFAVAPMITGSGGLTLAKHLGVPFVQEVIAVSTALQHYAPQTDVAIE
                     LGGEDAKIIYFEGGNVEQRMNGICAGGTGSFIDQMASLIQTDATGLNEYAKNYKAIYPI
                     AARCGVFAKTDIQPLINEGATREDLSASIFQAVVNQTISGLACGKPIRGHVAFLGGPLH
                     FLSELKAAFIRTLNLDDEHAITPENSHLFAAIGSALNYKPGETTTLVSLRDRLANGIKM
                     EFEVARMDPLFASQEEYDAFRARHDGHNVRSADLSTYEGNCYLGIDAGSTTTKIALVGE
                     DGSLLYSFYSNNNGSPLATAIRSIKEIYTLLPPKAKIVHSCSTGYGEALLKAALMLDDG
                     EVETVAHFYAAAFFDPEVDCILDIGGQDMKCIKIKNQTVDSVQLNEACSSGCGSFIETF
                     AKSLNYSVQDFAKEALFAKNPIDLGTRCTVFMNSKVKQAQKEGASVADISAGLAYSVIK
                     NALFKVIKLSDASQLGKNIVVQGGTFYNDAVLRSFEKIAGVECVRPDIAGIMGAFGAAL
                     IARERHEAGYQTSMLSIEQINALTFDTKLARCQGCTNHCLLTINRFSGNRQYITGNRCE
                     RGLGKEKNKDNIPNLYEYKNKRLFDYTPLSAEEAARGTVGIPRVLNMYENYPFWATFFK
                     KLGFSVVLSPQSTRKIYELGIDSIPSESECYPAKLAHGHVTWLLHQNVDFIFYPCIPYE
                     RNEFPDSNNHYNCPIVTSYAENIKNNVDEITSGQVKFLNPFMSFASEETLSSQLIKTFG
                     QSEFRIPESEIRDAVAEGWKELAVCRMEMQKKGEEVLQYLKETGRRGIVLAGRPYHVDP
                     EINHGIPELITSYGIAVLTEDSISHLQPVERPLIVMDQWMYHSRLYAAANYVKTRDDLD
                     LIQLNSFGCGLDAVTTDAVNDILTKSGKIYTCLKIDEVNNLGAARIRIRSLISAIRVRE
                     KKQTKRTIVPANYNRVVFTEEMRKNYTILCPQMSPIHFELLEPAFQTAGYNLVVPDVDS
                     RTCVDVGLKYVNNDACYPSLIVVGQLMAAVMSGGYDMSRTAVLISQTGGGCRASNYIGF
                     IRRALEKAGYPDVPVISINLSGLEKNPGFKLTLPLIQHGLYALEFGDIFMRCVYATRPY
                     EAVAGSTDELHEKWKKEVIAFITQKKMLSHGKFKKMCREIIRDFDNLPRKDIKKPRVGV
                     VGEILVKFHPAANNHLVELLESEGAEAVVPDLTDFLLYCFYNTGFKADNLGMSQKSKKI
                     GRLGINFFEWLRSAARDEFTKSRHFTAPAHIDDLARYARDIVSEGNQTGEGWFLTGEML
                     ELIHTGTPNIVCTQPFACLPNHVVGKGVIKELRHRYPGSNIVAIDYDPGASEVNQLNRI
                     KLMLSTANKNLAKQNAPEQKDQAAG"
ORIGIN
        1 tcctgcggag cccggattcc gacgaacacc gctctctcag cgccgaggtc cccaacagac
       61 tgacggattt ccaccgtgat gtcttcgtcc gaaaaacacc cgagggagag gattccctga
      121 ttgccggttg ccgggtagct ctcattgtac agatcattgt aatccgggac gtagagcctc
      181 tccccgttta ccgtaatttc tgcctgctgc agatcctttc catagagata taagatctgc
      241 tttccatccg cgtaaaaccg gtacgataat tccgctccgg tctgatcatc cagataggtc
      301 tcttttttcc agtcgatggg agttgtgtga aaaagcagct ccgacagccg gttctggttc
      361 tcaaacacat tttccgtgta cgcttccgtg actgcatacg cttcatagtc cgcttttgtg
      421 ataaaaaatg ccctgtcccc gacgggcgca ttttcccaca gcgtaaactt ttcggtctca
      481 gcaagcggcc aaagggaatc cgccgccgtg tcttttcccc acgatcccgc cttagacgcc
      541 acataataac ggtaccccag catgatgtcg gacgcgagcg ttccgcccgt gtcacttaat
      601 ctggtccaca cctgagaata cccgagcagt gtgttcatcc tgatctgctc cgacgtcatc
      661 agatgcagat aattggagta ggaggtgctc tctgcgatca gcggatagtt gttgtcaatc
      721 gctccgtccg ccagctttgc cttgtggaaa acatcggttt ttccagcaag cggctgaccg
      781 atttccgtgg catccccaac aaaatccgtc tcgtccgtgt gcgtttccgg ctgtatcaaa
      841 gaaatgccaa gcgccaccat ctgcacgcac cagattccca ggaacgcata taaaatgttc
      901 cgccgcacgc ggctatctcc cacaaaatcc ggcacgcgcg ccgctgccat acaaatcacg
      961 gcaaacacca gcatataacc atatcgcatc gggaagcaca catacgtccc gcggtgccag
     1021 atgagattga ccgcctcgaa gaaaaccggc agcaccatcg ccgccaccag ataccactgc
     1081 cagatgtgct cccgcttccg tctgccagaa atgacgaaga acagcagcgg aaccgccacg
     1141 ctgccaagaa tcacccattt ccacaccgcg tccattccgt cctgccgaag cagcagaaaa
     1201 tagccggaga ttccccggta ctcctcgctc gacagccggt aggaaccaag cattgccctc
     1261 gctgccggca gaaatattac cgccgcaatt ccaagcgaca gtaaagaagt cagcccgaat
     1321 tttaaaatgc cgttcttttt tagcggctgg tcctgtcgtt tcaggaaaaa atatcctccc
     1381 gcaaacacga tcaggaaaaa acacatcatg tacgcctgcg gaatattgat gaggaatacc
     1441 agcgtcaggc agacgatata gccgagcgta tttttcccga gacgccagtc cccttcccgc
     1501 tccgccatcc tgcagaagaa ataacacaat agcggcagga tcgctgccac atccagccag
     1561 cccatgccat agtacaaaag cgtatagccg tttacggcat accccacgct tcccgccaga
     1621 atgtagattc cgtaacgctc ttccttaagg atctgctctt ttaaaaacca gcgcatgcca
     1681 tagcccatgg caagcagctt gattaaaaga aacacgatca tggatttttc aatccagctt
     1741 cttttcacaa agaggaagaa caggttaaac gggctgaaca gagaaaactg cgcgctcact
     1801 cccgcaaaat tattcccgcc gccgactctc cagtcaaaaa aggcgctgcc gtctccgtgc
     1861 agcacgtccc atacatggta atatgccgga atccactggg actgaaaatc cacagtgtca
     1921 agcgtggcaa ttccaaacgg atagatgccc tttatgatgc acaacagcag aaaaatggca
     1981 gttgtcacgc agccgacggc ggcacgtgaa acaaacgtat tttttttact tttcatccgg
     2041 acaatctctc ctcgctctcc gaaatactct ctcaaaaaga aaagggataa tacattttat
     2101 atactatccc tcttaaaaat cttcttattc agttacatct tccggcttct caactgcgga
     2161 gatggccgcc ttctgcatcg ggatgcggca gttcttgttg cttccgaact caacgattac
     2221 tgtatcatca gcaatatcga tcacggttcc ataaaaaccg cttgttgtta agatcgtatc
     2281 tcccactgca agttctgcaa gcatggagtt cttcttctgc tgttccttct tctgcggacg
     2341 caccatgaag aaatacataa acgcaaataa aataaccagc cacaccacca tactgatcca
     2401 gccagcggat gacgcactct ctgttgctaa gattgaaaac atctgatatc ctcctaaaat
     2461 cataaacttg tccgaagtca tccgacttca ttaaagagta ttgtacacaa aacctcgccg
     2521 tttggcaagc cttttccctt ttacttttac tttgccattt ccttttcccg gttgatctgt
     2581 cccatgccgt atagcttttc ttccttgtag gaggcaaaat ttccggcatc cagcgcatcc
     2641 cggatctctt ccatcatcgt gttgtagaag tacagattgt gcagaacgca taagcgcatg
     2701 ccaagcatct cttttgcctt gagcagatgg cggatatagg ctctgctgta gcggcggcag
     2761 gtcgggcacc cgcagccctc ctcgatcggg cgcatatctt tctcgtactt ctggttgaac
     2821 aggttgatct tgccctgatt cgtgtataca tgaccgtggc ggccgttgcg ggacggataa
     2881 acacagtcaa agaagtcaat gccgcgctcc actccctcca gaatattggc cggcgttccg
     2941 actcccatga gataggtcgg cttgttcacc ggaagatacg gcacggtctc atccagcaca
     3001 tggtacatct cctcatgtgt ctcgccgacc gcaagtccgc cgaccgcata gccgtccaga
     3061 tccatctcgg aaatccgctt tgcatggtcg atccggatgt ccgtgtagat ggctccctgg
     3121 ttgatgccga acagcatctg gtgacggttc acggtatcct ccagaccgtt gaggcgctgc
     3181 atctcattct tgcagcgctc cagccagcgc gtcgtccgtg ccacggaatc ctccacatat
     3241 ttccgctcgg caagcgccgg cggacattca tcgaacgcca tggcgatcgt ggagccgaga
     3301 ttggactgga tctgcatgct ctcctccggt cccatgaaaa tctttgcccc gtcaatatgc
     3361 gagtggaaat agacgccctc ctccttgatc ttgcggagcc cagccaggga gaacacctga
     3421 aatccgccgg aatccgtaag aatcggacga ttccatgaca taaacttgtg cagtcctccc
     3481 acttccttga tcagcttgtc tccggtgcgc acatgcagat ggtaggtgtt tgacagctcc
     3541 acctgacact tgatctgctc taaatcttcc gtggagacag ctcccttgat ggcagccacc
     3601 gtacccacat tcataaatac cggcgtctgg atatctccgt gcaccgtatg gaaaacgcct
     3661 ctcttcgcgc gtccttcctg ctttaataat tcatacatct gtttttcgtc tccttttatt
     3721 gcctgtagtt cttctttatt ttctctggtt ctgcgctttt tccgctttca cttccaccag
     3781 ccttgtgcag tccggcatct tgtcagcctt ccaccgtttt cccagtcagt tcgcttaaca
     3841 cggtaaaata attttcaaac gtcttgcggc agcacgccgg gttctcaatg acaatcccgt
     3901 cggttctaag tccgaccagg gaaaatgcca tcgccacgcg gtgatcgtcg tatgtctcca
     3961 cgcttccgcc gtgggggctg ctgggataga tcgtggcagc cgtctcttcc tcctcacacc
     4021 ggatgccaag cgctgtcagg ttcgtctgta tcgcgtgaat ccggtcgcat tcctgcccac
     4081 ggatatgtcc gattccctct atgcgcaccg gcgcgtcggc aaacggcgcg atcgccgcca
     4141 gggtcagcgc ctgatcggaa aaatcgttca tattgactgt gatgccccgt agcgcaccgt
     4201 ccgccggtcc cgttaccagg atgccctccg gcgtatcgtc cgcggtacat cccatgtgct
     4261 ccaacacttc caggaaacgc agatctccct gtgtgttgtc catatgcaca tgccgcacaa
     4321 gcgcccgtcc gccggtcata gccgcagccg cataaaaata gcaggcagcc gacatatccg
     4381 gttccaccat ataagtctct ttccggtagg aacttctgca cggcacctcg tagtctcttc
     4441 cgtcaaaagc gacactcacg ccgaattcct gcatcatctt ccgcgtgatg cggatgtatg
     4501 agccgtccgt cttctcactg gtgatgtgga tcttcatccc ttccggaacc atcggcgcaa
     4561 tcaacagcag cgcgcttaaa aactgtgtgc tcttcgtaat gtcaagagag agctcccgcg
     4621 gcgtctcccc tgctgtctta tccgcccggg cgtatctgca tcctgtgatg cgcaccggaa
     4681 gatgcccttc ctcctcgagg aatgtaatct tcgctcccgc accggaaagc agatcgaaca
     4741 gctccgccat cggccgccgc ttcatctgcg ctgagcagcg gatctcatag cacccgtccg
     4801 aaaatccgag catcgccgca agaaaacgcg ccgctgtccc ggcgcttccg acgtcgatta
     4861 ccgcctcccc gcggggaatc ctgccgccgc agcccgtcac ggtcacgcac tttttttctt
     4921 cctctatctc cactgtaaag ccgagcgcca caagacacgc cagaaagtgt ctggaatcat
     4981 cggaaaacag gactccttcc acgcgcaccg tccctgcgga cagcactgcc ataagaagcg
     5041 cgcggttcgt catgctcttc gatcccggca cggttacctt ccagtccacc ggctctgtta
     5101 tctttttcac aaggtatttc tctatcatga aatattcttc tcctcgcctg ctggtacttc
     5161 tgctccgtca aatcataaca tatttctgtt gcggcgcaaa gtcaaatctt ttataatcga
     5221 gaaagatcat tatgtaagca ggagggaatc acatggcagg gtctactttg ggaactcttt
     5281 ttaaaatcac aacctggggg gaatctcacg gaaagggcgt cggcgtcgtc atcgacggct
     5341 gtccggcggg actttctctc tgtgaggcgg atatccagaa gtttctcgac cggcgcaagc
     5401 ccggtcagtc cagatatgca acgccgcgca aagaggacga cgccgtagag attctctctg
     5461 gcgtgtttga aggaaagacg accggcaccc cgatctcgct tgtcgtcttc aaccgcaacc
     5521 agcagtccaa agactacagc gagattgcct cctattaccg tcccggtcac gccgattaca
     5581 cgttcgacca gaaatacggc ttccgcgact accgcggggg cgggcgctcc tccgggcggg
     5641 aaaccatcgg gcgtgtcgcc gccggcgccg tcgccgtcaa gattctaaac gagctcggca
     5701 ttacctttat gacctacaca aagtccatcg gcccgatcgc cgtatcttcc gggcgctttg
     5761 atttttccga ggtcacaaag aatccgctct atatgccgga cgccgaagca gccgagaacg
     5821 ctgaaaatta tctggatgcc tgcatgacgg agttaaattc ctccggcggc attgtggagt
     5881 gtatcataaa ggggatgccc gccggcatcg gagatccggt cttcgagaag cttaatgcga
     5941 accttgccaa ggcggtcatg tccatcggtg ccgtcaaagg ttttgagatc ggggacggat
     6001 ttgacgtagc aaaagcgacc ggcaagaaca acaacgatgc ctttgtcctc agtgaggacg
     6061 gcaggattgc caaagcaacc aaccatgccg gcggtatctt aggcggcatg agcgacggaa
     6121 gcgacatcat ccttcgggct gccatcaagc cgaccccttc catcgccgcc acacagcgca
     6181 ctgtcaatca gtccggggag gagatctcgg tcaacatcaa gggacgccac gatccgatca
     6241 tcgttccgcg cgccgttgtc gtggtggaat ccatggcagc catcacgatc gtcgacgcac
     6301 ttttttccaa tatgagtgca cggatggatg cgctaaaaga tttctactcc taaaagaaag
     6361 aaaaaggtga tacttcttct ccgccggctg gcggaatcga agtatcacct ttttcttttt
     6421 catactttct agctcatccg aatatgctga tgtgtaaaca gatgatcctg acagtattcg
     6481 taattgccct cgcacttgga gcagaaacgg aattccagcg tcggatcgtc aagttccgtc
     6541 ctgccgcaga cagcacactt gtgcttcgca ccgcccgcat atccctgcgg tctgcgcatg
     6601 tctgccttaa acttctggcg tctgtgcacc tcgtgcggcg tatagcgctt gaggtttctg
     6661 gtggagaaga agaaaataat aaagttgaga agcgacataa aaatcgcgac tcttcccgcc
     6721 catccggtct caaagaagct taaagcaatc agaacgccgt acacaaccgc catccacttc
     6781 atcttaatcg ggataatgaa catcagaaga acctgcatat ccggatacat acatgcaaac
     6841 gcaaggaaga tggacatgtt gatgtagctt gtgctgaagc ttgttccaat cagaagcatc
     6901 tccgtcgtca caccgccgtt caaaagatac atgataccgt acagcagaaa cgctccgatg
     6961 acggtaaaca gcatacctcc gaaaatatag acgttaaacc ggaaggttcc ccatgtgcgc
     7021 tccagtgccg ttccaagctg ataatagaaa agcgccataa tgagaagata caccagattc
     7081 gtgtctgtgg gcataaacac ccaggtaatc aggcgccaga cctgtccgtg caggatgtga
     7141 tacgggctca acatcaaaag tcctatgatc gatgggttca cctggtagag gacaaatccg
     7201 atcgtgtaag ctccgatcag ccacacgatc agattgggaa tcgcccagtt gccgaattta
     7261 cgttctaatt tatttaacca gttcatacac tctgttcctg acctttccaa aaatgacatt
     7321 acgttgttca gtatatcggt cggggaaatc tttgtcaatc agagggattc ttctttacaa
     7381 aaagtttata cttttccggc aaaatgcaca ttgtcttttg acatatcctg tcgtataatg
     7441 tagagtgttt agcgccagat tggcactatt tataataaga agaaatcttt tacatatttt
     7501 actctgctaa agtatttact ttacgagaaa cagccatgga gggaattatg gaaaacaata
     7561 cacttcataa attgggaatc gacatcggtt ccacaaccgt caaggtcgca attttagacc
     7621 agaaggatca tctgctcttc tctgattatg agcgccattt tgccaatatc caggagacct
     7681 tatcctccct tctccagaaa gcttacgatg cactcggcga ctttgctgtt gcaccgatga
     7741 ttaccggttc cggcggtctg acactcgcca agcatctcgg tgttccgttt gtccaggaag
     7801 tgatcgccgt gtccactgcc ctgcagcatt atgcaccgca gaccgatgtt gccatcgagc
     7861 tcggtggtga ggatgccaag atcatctatt ttgagggcgg caatgtcgag cagcgtatga
     7921 acggcatctg tgccggcggt accggttctt ttatcgacca gatggcatcc ctcatccaga
     7981 cggatgcgac aggtctgaat gaatacgcca agaattacaa ggccatctac ccgatcgctg
     8041 cgcgttgcgg tgtctttgcc aagaccgata tccagccgtt aatcaacgag ggtgctacca
     8101 gagaggatct ctctgcctcc attttccagg cagtggtcaa tcagacgatc agcggtcttg
     8161 cctgcggtaa gccgatccgc ggtcatgttg cctttctcgg aggtccgctt cacttccttt
     8221 ccgagctcaa ggctgctttt atccgcacct tgaatctgga cgacgaacac gccatcacac
     8281 cggagaattc ccatctgttt gctgcgatcg gttccgcttt aaattacaag ccgggtgaga
     8341 cgaccacgct cgtctctctc cgcgaccggc tcgcgaacgg catcaagatg gaatttgagg
     8401 ttgcccgtat ggatcctctg tttgccagcc aggaagagta cgacgctttc cgtgcgcgcc
     8461 acgacggaca caatgtcagg tccgcagatc tctccactta tgagggcaac tgctatctgg
     8521 gcatcgatgc aggttccacc acgaccaaga ttgccttagt cggcgaggac ggttcccttt
     8581 tgtattcttt ctacagcaac aacaacggaa gtccgcttgc aacggcaatc cgttccatca
     8641 aggagatcta tacgctcctt ccaccgaagg caaagatcgt ccactcctgc tccaccggat
     8701 acggcgaagc gctgttaaaa gccgctttga tgctcgatga cggcgaggtt gagacggtgg
     8761 ctcatttcta tgcggccgcg ttcttcgacc cggaagtcga ctgtatctta gacatcggcg
     8821 gtcaggatat gaaatgtatc aagatcaaga atcagacggt ggattccgta cagctcaatg
     8881 aggcttgttc ctccggctgc ggttctttca tcgaaacgtt tgcaaaatcc ctcaactact
     8941 ctgtacagga ttttgcaaag gaggctcttt ttgccaaaaa tccgatcgat cttggaaccc
     9001 gctgcaccgt atttatgaat tccaaggtaa agcaggcgca gaaagagggc gcatccgttg
     9061 cagatatttc tgcgggtctt gcgtactctg tcatcaagaa tgctttattt aaggtaatca
     9121 agctttccga tgcaagccag ctcgggaaaa atatcgtcgt acagggcggt acgttttaca
     9181 acgatgccgt actgcgcagt tttgagaaaa tcgctggcgt cgaatgtgtc cgtccggata
     9241 ttgccggcat catgggtgct ttcggtgccg cactgatcgc cagagagcgt cacgaagcag
     9301 gctaccagac ctccatgctt tccatcgagc agatcaatgc gctgaccttc gacacaaagc
     9361 tggcaagatg tcagggatgt accaaccact gtctcctcac aatcaaccgc ttttccggca
     9421 accgccagta tatcaccggc aaccgctgtg agcgcggcct cggcaaggag aaaaataaag
     9481 acaacattcc aaacctctac gaatacaaga acaagcgcct gtttgactac accccgcttt
     9541 ccgccgagga agcagcacgc ggcacagtcg gtattccgcg cgttttaaat atgtacgaga
     9601 actacccgtt ctgggcaact ttctttaaga agctcggttt ttccgtggta ctctccccgc
     9661 agtcgacgcg caagatctac gagcttggaa ttgattccat cccgagcgag tccgagtgct
     9721 acccggcaaa gctggcacac ggtcatgtga catggctgct ccaccagaac gtcgatttta
     9781 ttttctaccc gtgtattcct tatgaacgca acgaattccc ggattccaac aatcactaca
     9841 actgtccgat cgttacctcc tacgcggaaa atatcaaaaa taacgtggac gagatcactt
     9901 ccggtcaggt gaagttctta aatccgttta tgtctttcgc cagcgaggag acgctttcct
     9961 cccagctgat taagaccttt ggccagtcgg agttcaggat tccggaatcc gagatccgcg
    10021 acgcggttgc cgaaggctgg aaggagcttg ccgtctgccg gatggagatg cagaaaaaag
    10081 gcgaggaagt cttacagtat ttaaaggaga ccggaagacg cggtatcgtc ctcgcaggtc
    10141 gtccgtacca tgtagaccct gagatcaacc acggtattcc ggagctgatt acctcctacg
    10201 gcatcgccgt gctcacggag gattccatct cccacttaca gccggtggag cgcccactca
    10261 tcgtcatgga tcagtggatg tatcactcca gactgtacgc agcggcgaac tatgtcaaga
    10321 caagagacga tctcgacctc atccagctga attccttcgg ctgtggtctg gatgccgtca
    10381 cgacagacgc tgtcaatgat attctgacaa agtccggcaa gatctacacc tgcttaaaga
    10441 tcgatgaggt caacaacctc ggtgcggcgc gtatccgtat ccgttccctg atctcggcga
    10501 tccgtgtccg tgagaagaag cagacgaagc gcaccatcgt tccggcgaat tacaaccgcg
    10561 tcgtcttcac ggaggaaatg cgcaagaatt acaccatcct ctgcccacag atgtcaccga
    10621 tccattttga gctgttggag ccggcgttcc agacggccgg gtacaacctt gttgttccgg
    10681 atgtggacag ccgcacctgc gtggatgtcg gcttaaagta tgtcaacaat gacgcctgct
    10741 acccgtccct gatcgtggtc ggccagctga tggcggccgt gatgtccggc ggttatgata
    10801 tgtcgcgcac cgcggtctta atctcccaga ccggcggcgg ctgccgcgcc agcaattaca
    10861 tcggcttcat ccggcgtgca ctggaaaaag ccggctatcc ggacgttccg gtcatctcga
    10921 tcaatctgag cggtctggag aagaacccgg gctttaagct gacactgcca ctgatccagc
    10981 acggactcta cgcgctggag tttggcgata tcttcatgcg ctgcgtctac gcaacgcgcc
    11041 cttacgaggc ggttgccgga tcaacggacg agttgcacga gaaatggaaa aaagaggtta
    11101 tcgcctttat cacccagaaa aagatgctct cccacggcaa gttcaagaaa atgtgccgcg
    11161 agatcatccg cgattttgac aaccttccgc gcaaagacat caagaaaccg cgcgtcggcg
    11221 ttgtcggcga gattcttgtc aagttccatc cggctgccaa caatcatctg gtggagcttc
    11281 tcgaatccga gggtgcagag gccgttgtac cggatctgac cgatttcctg ctctactgct
    11341 tctacaatac gggctttaaa gcagacaatc tcggcatgag ccagaagtcc aagaagatcg
    11401 gccgtctggg catcaatttc tttgagtggc tgcgcagcgc tgcaagagat gaattcacaa
    11461 agagcaggca ctttactgca cctgcgcaca tcgatgatct tgccagatat gcaagagaca
    11521 ttgtatccga gggcaaccag accggcgagg gctggttctt aaccggtgag atgttagagc
    11581 tgatccacac cggaacaccg aacatcgtct gcacgcagcc gttcgcctgc ctgccgaacc
    11641 atgtggtcgg caagggtgtc atcaaggaac tgcgtcaccg ctatccgggt tccaatatcg
    11701 tggccatcga ttacgatccg ggtgccagcg aggtaaacca gctcaaccgt atcaagctga
    11761 tgctctccac cgcgaacaaa aatctggcaa agcagaacgc accggagcag aaggatcagg
    11821 ctgcagggtg acagatacag agaaaggggc tacgcatcaa atgtgcagcc ccttttcgtg
    11881 ataagtaata ttatcaaaag atcacaccgt gggatttcag atggagatac agagggaaat
    11941 ttggttcaaa aaatgtggca tttctaacca gccggatgtt tgcatcttcg atgatccgtg
    12001 tctttccaag tttggagcac tccgcgggtc atgtccgcat cccggaagac aatttgtagg
    12061 acttttgtgt gtgtccctta tggcacacct ctgaacaaaa cataaccgcg cgaagccgat
    12121 gtctgagtcg gcatctgcct
//
