LOCUS       gnlProkkaNGKEMLHH_42    7540 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NGKEMLHH_42.
ACCESSION   gnlProkkaNGKEMLHH_42
VERSION     gnlProkkaNGKEMLHH_42
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 06:29:09
            Original ID  :: gnl|Prokka|NGKEMLHH_42
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7540
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7540
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2012:3601]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2013..3601
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..7540
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7540
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             34..1539
                     /locus_tag="ctg42_1"
                     /transl_table=11
                     /translation="MSNNIRIRKKKLKGTGIFAAAALTAALIAGNNIPGVTRQVSAAES
                     QENTVSSLIPDNITLDKPVELADVELPATEYGTFEWADGSFVPAQRVQSCEVLLIPAEG
                     QDLSHVDGWDPESGAVVGYINVIVNSITDSDNVDKTEGSGKTDPTENADPTETPETSSE
                     KPAADENADTDNKEDKESKSDQDNKTDTDNEENKIEEDKTDNKNNKDNNSNADKTDKDT
                     ETTGKLEPADDMTQDKEDTKKDDEDGAGDNIFDNPVLPDDKDDRPTDAEDSLSDEEKEE
                     RAALNHTCDGITVSGVNLPWYVQFRVSSGDSYQFTNESDAMIFQSYEFELWDLKNNTEY
                     EIPNGDYISVTVPVKSGYQYTIEHLLDNGATETIIPSVENGIMVFSTHSFSPFGIAGSR
                     QLVGPDAGNDTDDTDAVTPAPASSDSQSSDSGKNNTVSVNDSSDSNNGSSSDQNDNSTE
                     NKAVKNNNTVNTGDTTSIMPFVILFVAAAVIAGVAVFIKKRKK"
     CDS             1589..1939
                     /locus_tag="ctg42_2"
                     /transl_table=11
                     /translation="MKVRAILKSLLFAYALTGVALLLLALVLFAFDLGETAVDAGIIII
                     YVLACFMGGFMAGKIVRKDKYLWGVITGLAYYVLLLTVSVMAKGGWDMSAAHAVTTFFM
                     CTGGGTLGGMLS"
     CDS             2013..2153
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_3"
                     /sec_met_domain="TIGR03973 (E-value: 1.4e-28, bitscore:
                     87.3, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.8e-28, bitscore: 87.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHIKTLNTKNLQNTVKKGGCGECQTSCQSACKTSCTVGNQSCEQ
                     K"
     CDS             2234..3601
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_4"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 6.9e-30,
                     bitscore: 92.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.7e-17, bitscore: 51.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.1e-15, bitscore: 45.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1e-20, bitscore: 62.7,
                     seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLIHRYKSNGFNIVLDINSGCIHLVDEVTYEVLPYLEEGLGTEA
                     IAEKLENKYNREDIETSVRECNKLKEDGMLFTKDVYENVIEEFSNNRQTVVKALCLHIA
                     HDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGSRKNLEVDFFGGEPLMNW
                     QVVKDLVKYGREQEKLHNKKFRFTLTTNGVLLNDEVMEFCNKEMGNVVLSVDGRKEVHD
                     YMRPFRKGAGSYDLIMPKFQKFAESRNQDKYYVRGTFTHHNLDFSKDVLHLADLGFKQI
                     SVEPVVAADTEEYAIREEDIPQIMEEYDTLAKEMIKREKEGKGFNFFHFMIDLTGGPCV
                     YKRLSGCGSGTEYLAVTPWGDFYPCHQFVGEEQYLMGNVDEGITKPEIQKEFGGCNVYT
                     KKDCKDCFARFYCSGGCAANAFHFQGDIKGNYEIGCELQRKRVECAIMIKAALACD"
     CDS             3713..6121
                     /locus_tag="ctg42_5"
                     /transl_table=11
                     /translation="MKKSKGIVVLLLTLILTVFFCFTAAVGIGPTGTGAAKHINTGLDL
                     AGGVSITYQAKESNPTSEEMSDTIYKLQKRVEQYSTEAQVYQEGSDRITVEIPGVTDAD
                     TILNDLGKPGSLYFITKEDADGNQNFTTGQDGYVLSRTMDEIKESGSVVLEGSDVADAQ
                     GGAIQNQNTSAKEYVVSLTLTSDGENSGKTKFAEATKNNVGKQIAIVYDNNIISAPNVN
                     EEISGGKAQISGMSDLEEAQNLASYIRIGSLGLELEELRSSVVAAQLGEEAISTSVLAG
                     AIGLIIVIIFMIIAYRVPGVVAGIALILYTSLMLITLNAFDITLTLPGIAGIVLGIGMA
                     VDANVIIYARIREEIGAGVSVRNSIKSGFSKAFSAIFDGNITTLIAAFVLMWLGSGTVK
                     GFAYTLALGIVISMFTALVVSRLIVNALYAVGVRDPKFYGSAKERKAVDFLGKKKVFFA
                     ISIILILCGPAAMFANSHAGNKALNYSLEFSGGTSTTVTFNEDMDIKTIDSEVTPVVEE
                     VTGDKNVQPTKVVGTNQVVIKTRSLNQSEREALQSALVEKFGVDDSTISTESISSTVSS
                     EMRRDAIVAVIVATICMLLYIWFRFKDIRFASSAVLALLHDVLVVLAFYAIARVSVGNT
                     FIACMLTIVGYSINATIVIFDRIRENLHSGSREKLAEIVNTSITQTLTRSIYTSFTTFV
                     MVAVLYIMGVSSIREFAAPLMVGVLVGAYSSVCITGALWYVMKKKFAGKGQPAIAAASA
                     SAKSSSKPKKARDVSQKDPTQPKKKNRKRVAERLAAEEAAKKQQNDDAE"
     CDS             6203..7540
                     /locus_tag="ctg42_6"
                     /transl_table=11
                     /translation="MEKWVIAAKRADFNQIGQQFHIDPVIARLIRNRDVIGEDKIREYL
                     SGTVQELPSPWLMKDMEKAVDILEKKISQKAKVRIIGDYDIDGVTSTYILMKGLARIGA
                     DVDTYIPDRVADGYGIHAHLIERAETDRIDTIVTCDNGIAAAAEIQMAKDKGMTVIITD
                     HHEVPYREEKGERQMVLPPADAILNPKQYDCPYPNKNLCGAVVAFKYIAALYERFGVPA
                     EELEDYYELAAIATVGDVMDLQGENRILVKEGLCRLKNTKNQGLQELIRANSLEDAKIT
                     AYHIGFVLGPCINASGRLDTAARSLALLNAKTKEEAARLAGDLTALNQSRKALTEKGKE
                     EAIRIIETTELKNDRVLVVYLPDCHESLAGIIAGRIREKYHRPAFVLTGGETSAKGSGR
                     SIESYSMYEELVKCADLMIQFGGHPMAAGLSIEEKNIEEFRRRLNVN"
ORIGIN
        1 cataagaatc gaatataaat atagaggtgc gatatgtcca ataatataag aataagaaaa
       61 aagaaattaa aaggaacggg tatttttgcg gcagcggctt taacagcggc tttgattgca
      121 ggaaataata taccgggtgt aacaagacag gtcagtgcgg ctgagtcaca ggagaatact
      181 gtgtcttctc tgattccgga caacatcacg cttgataagc cagtagaact tgcggatgta
      241 gaacttccgg caacggaata tggaactttt gaatgggcag atggaagttt cgttcctgca
      301 cagcgtgtac agagctgtga ggtacttctt ataccggcag aagggcagga tttaagccat
      361 gtggatggat gggatccgga gagcggcgcg gttgtcggtt acatcaatgt aatagtgaac
      421 agtattacgg atagtgataa tgttgataag acagaaggct caggtaaaac agatccaaca
      481 gaaaatgcag atccaacaga aacgcctgaa acttcgtcag aaaaacctgc cgcagatgaa
      541 aacgctgata cagacaataa agaagataag gaaagtaaat cagatcagga taataaaact
      601 gatacagaca atgaagagaa taagattgaa gaagataaaa cagataataa aaacaacaaa
      661 gataataaca gcaatgcaga taagacggat aaagatacag aaactaccgg taagctggaa
      721 cctgcagatg atatgacaca ggataaagaa gatacgaaga aagatgatga agatggcgca
      781 ggtgataata tctttgataa tcctgttctg ccggacgata aggatgaccg tcctacagat
      841 gcagaggatt ctctttctga tgaagaaaaa gaagagaggg ccgcacttaa tcatacctgc
      901 gacggtatta cagtaagcgg agttaatctt ccatggtatg tacagttcag agtttcaagc
      961 ggtgacagct atcagtttac caatgaatca gatgcaatga ttttccagtc ttatgaattt
     1021 gaactctggg atcttaagaa taatacagaa tacgagatcc ctaatggaga ttatatcagt
     1081 gtcactgtgc cggtaaaatc cggatatcag tatactatcg aacatctcct ggataacggg
     1141 gcaactgaga cgattattcc gagtgtagag aatggtatta tggtattcag cacacattct
     1201 ttcagtccat ttggaattgc aggaagcaga caattagtag gacctgatgc ggggaatgat
     1261 acggacgaca cagatgcggt aactcctgca ccggcttcct ccgacagtca gagctctgat
     1321 tccggaaaga acaatacagt atctgtgaat gacagttctg acagcaataa tggttcttct
     1381 tctgatcaga atgataattc aacggaaaat aaagctgtga aaaataacaa tacagtaaat
     1441 accggagata caacatcaat tatgccgttt gtgatactgt ttgtggcagc tgcagtgatc
     1501 gccggtgtgg ctgtatttat aaaaaagaga aagaaataaa agaataacac tgattcctcc
     1561 cccatatagt ttaacaggag gggaagcaat gaaagtcaga gcaattttga aatcactatt
     1621 atttgcatat gcattaacag gagtggcatt actgcttttg gccctggtac tgtttgcttt
     1681 tgatctggga gaaacagctg tagatgcggg gattattata atttatgtac ttgcatgttt
     1741 catgggaggc tttatggccg gcaaaattgt gcgtaaagac aaatatctgt ggggtgttat
     1801 cacaggcctg gcttactatg tattactgtt gactgtctct gttatggcaa aaggcggctg
     1861 ggatatgagt gcagctcatg cagttacaac attttttatg tgcacaggcg gtggaacact
     1921 gggtggaatg ctgtcgtaaa aaaaagcttt taaaatgaaa agatatatga tatactatgc
     1981 caagaatata attacataag gaggatagag ttatggaaca tatcaaaacc ctgaatacaa
     2041 agaatttaca gaacactgta aaaaaaggtg gatgtggcga gtgccagact tcctgccagt
     2101 ccgcatgtaa aacttcctgt acagtaggaa accagagctg cgagcagaaa taagatcagc
     2161 tatggagaaa tgagataagc agcggaactt ttattccgct gcttatctta cgcttagaaa
     2221 ggattttagt aaaatgagtc tgattcaccg ttataaaagc aatggcttta atattgtact
     2281 ggatatcaac agtggatgca tccatctggt agatgaggtt acatatgagg tccttccata
     2341 tctggaagag ggccttggca cagaagctat tgcagagaaa ctggaaaaca aatataacag
     2401 agaagatatt gagacatctg taagagaatg taataagctg aaagaagatg gaatgctttt
     2461 tacaaaagat gtttatgaga atgtaattga agaattttca aataaccggc agaccgttgt
     2521 aaaagcattg tgcctgcaca ttgctcatga ctgcaatctg gcctgccgtt attgttttgc
     2581 cgaagaaggc gaatatcatg gcagaagagc tcttatgtcc tatgaagtcg gcaaaaaagc
     2641 tcttgatttc ctgatcgcga actccggttc caggaaaaac ctggaagtag atttctttgg
     2701 cggcgagccg ctgatgaact ggcaggttgt aaaagatctg gtaaaatatg gcagagagca
     2761 ggaaaagctt cacaataaga aattccgttt cactttaaca acaaacggag ttcttctgaa
     2821 tgatgaagta atggaattct gcaataaaga gatgggcaac gttgtactga gtgtggacgg
     2881 acgtaaggaa gtacatgatt acatgcgtcc attcagaaaa ggtgcaggaa gctatgacct
     2941 gatcatgccg aagttccaga agtttgcaga atccagaaat caggacaagt attatgtaag
     3001 aggtactttt acccaccata atcttgattt ctccaaggat gtgcttcatc tggcagatct
     3061 tggattcaaa cagatttctg tagagcctgt agttgcggct gatacggagg aatatgcgat
     3121 ccgcgaggag gatatccccc agatcatgga agagtatgat actcttgcaa aagaaatgat
     3181 taaaagagag aaagagggaa aaggatttaa cttcttccat tttatgatcg accttacagg
     3241 tggcccttgt gtatacaaga gactgtcagg ctgcggttca ggaacagagt acctggctgt
     3301 aacaccctgg ggtgattttt acccatgtca ccagtttgtt ggtgaagaac agtatctcat
     3361 gggaaatgta gacgaaggca tcacaaagcc ggaaatccag aaggaattcg gcggatgcaa
     3421 cgtttacaca aagaaagact gcaaagactg cttcgcacgt ttctactgta gtggcggatg
     3481 tgcggcaaat gcattccatt tccagggaga tatcaaaggc aattatgaaa tcggatgcga
     3541 actccagaga aaacgtgtgg agtgcgccat catgataaaa gccgcactgg catgtgatta
     3601 gtgggcagta atctgtctga ctgataccgc cgtcggctgt tatcataaca gaaaatggct
     3661 ggcaggcgga tgaacatgac cgcggacaaa aaatcaagaa gggaaaagaa ctatgaagaa
     3721 aagtaaagga atcgtagtgc tgcttttgac actgatcctg actgtgttct tttgctttac
     3781 tgcagccgta ggtatcggtc ctaccggaac cggtgcagca aaacatatca acacgggtct
     3841 tgatcttgcc ggtggtgtca gcattaccta ccaggctaag gagagcaatc cgacaagcga
     3901 agagatgtca gatacgatct acaagcttca gaagcgtgta gagcagtaca gtactgaggc
     3961 tcaggtatac caggaaggat cagaccgtat tacagttgaa attcctggtg ttacagatgc
     4021 agatactatt ttgaatgatc tgggtaaacc aggttccctg tatttcatca caaaagaaga
     4081 tgctgacgga aaccagaact ttactacagg acaggatgga tatgttctct ccagaactat
     4141 ggatgagatc aaggaatccg gaagtgttgt tctggaaggt tctgatgtag cagatgccca
     4201 gggtggtgcg atccagaatc agaacacaag tgcaaaggaa tatgtggtaa gtcttactct
     4261 tacttctgat ggagaaaaca gtggtaaaac aaaatttgca gaagctacaa agaataatgt
     4321 aggcaagcag atcgctatcg tctatgacaa taacattatc agtgctccga atgtaaatga
     4381 agagatttcc ggcggaaaag cacagatcag cggaatgtct gacctggaag aagcacagaa
     4441 ccttgcttct tatatccgta tcggttctct gggactggaa ctggaagaac ttcgttccag
     4501 tgttgtagct gcacagcttg gtgaagaagc aatctctaca agtgttcttg caggtgcgat
     4561 cggtctgatc atcgttatta tctttatgat cattgcatac cgcgtacctg gtgtagttgc
     4621 aggtatcgca ctgattcttt atacatcatt aatgctgatc acgctgaatg cctttgatat
     4681 tactcttact cttccgggta ttgcgggtat tgtccttggt atcggtatgg cggtggatgc
     4741 caatgttatt atttatgccc gaatcagaga ggaaattggt gcaggagttt cagtaaggaa
     4801 ttctattaag tccggtttca gcaaagcttt ctctgcaatc tttgatggaa atattacaac
     4861 actgatcgca gcctttgtgc tgatgtggct tggttcaggt actgttaagg gatttgctta
     4921 tacacttgcc cttggtatcg tgatctccat gtttacagca ctggttgtat ccagactgat
     4981 tgtaaatgca ctttatgcag ttggtgtacg tgatccgaaa ttctacggat ctgcaaaaga
     5041 acgtaaggca gttgatttcc ttggaaagaa gaaagtattt tttgctattt ccattatcct
     5101 gatcctctgc ggtccggcag cgatgtttgc taattcgcat gcaggaaaca aagcgttaaa
     5161 ttacagcctt gagttctcag gcggtacttc tacgactgtt acatttaatg aagatatgga
     5221 tattaagacc attgattctg aagtaactcc tgttgtagaa gaggtgacag gagataaaaa
     5281 tgttcagcct acaaaggtag tcggaacaaa tcaggttgtg atcaagacac gttctctgaa
     5341 tcagagcgaa cgtgaagctc tgcagagtgc actggttgag aaatttggtg tagatgacag
     5401 cacgatttcc acagaaagta tttcttctac agtaagtagt gaaatgcgtc gtgatgcgat
     5461 cgtagccgtt atagtagcta caatctgtat gcttctttat atctggttca gatttaaaga
     5521 catccgtttt gcaagcagtg cggtattggc gcttctgcat gatgttctgg ttgtacttgc
     5581 attctatgct attgccagag tatctgtcgg taatacattt attgcctgca tgcttacaat
     5641 cgtaggttat tctatcaatg ctacaatcgt tatttttgac cgtatacgtg agaaccttca
     5701 cagtggttcc agagaaaaac tggcagaaat tgtaaacaca agtatcactc agactcttac
     5761 aagaagtatt tatacctctt ttacaacttt tgttatggta gctgttcttt atatcatggg
     5821 tgtttcttct atccgtgaat ttgcagcacc tctgatggtt ggtgttcttg tcggtgcata
     5881 ttcttctgta tgtattacag gtgcgttgtg gtatgtgatg aaaaagaaat ttgcaggaaa
     5941 aggacagccg gcaattgctg cagcttccgc atctgcaaag tcctcttcaa agccgaagaa
     6001 agcacgtgat gtatcacaga aagatccgac tcagccaaag aagaaaaaca gaaaaagagt
     6061 agctgaacgt ctggctgccg aagaagcagc taaaaaacag cagaatgatg atgctgaata
     6121 aaacaataat tgtctgaaaa acaggcagac agaaatatcc cggggtaaaa ctccgggata
     6181 tttttatgag gagagaaaat atatggagaa atgggtaata gcagcaaaaa gagcagattt
     6241 taaccagatc ggtcaacagt ttcatattga tccggtgatt gcgagactga tcaggaacag
     6301 agatgtgatc ggagaagata agataagaga gtatctgtca ggaacagtac aagagcttcc
     6361 ttctccctgg ctgatgaagg atatggaaaa agctgtagat atcctggaga aaaaaatatc
     6421 gcagaaagca aaagtccgta ttattggtga ttatgatatt gatggtgtga cctctacata
     6481 cattttaatg aaaggccttg cgaggatcgg agcagatgtg gatacttata ttccggacag
     6541 agttgcagac ggatatggga ttcatgcaca tcttatagaa agagcggaaa cggaccggat
     6601 cgatacgatc gtgacctgtg ataatggaat tgctgcggct gctgaaatcc agatggcaaa
     6661 ggataaggga atgacagtga ttattacaga tcatcatgag gttccttaca gggaggaaaa
     6721 gggagaacgc cagatggtgc ttccgccggc agatgcgatt ttgaatccga aacaatatga
     6781 ttgtccatac ccgaataaaa acctgtgtgg ggcagtggtg gcctttaaat atattgcagc
     6841 actttacgag agatttggtg ttccggcaga ggagctggaa gattattatg aactggcggc
     6901 tattgcaaca gtaggagatg ttatggatct tcagggagag aacaggattc tggtaaaaga
     6961 agggctgtgc cgtctgaaaa ataccaaaaa tcaaggattg caggaactga tccgagcaaa
     7021 ttctctggaa gatgctaaaa tcacagctta tcatatcgga tttgtgctgg gaccatgtat
     7081 caatgccagt ggcagactgg atacagctgc ccgttctctt gcacttctca atgcaaaaac
     7141 aaaggaagaa gcagcaaggc ttgccggaga tcttacagct cttaatcaga gccgaaaagc
     7201 tctcactgag aaaggaaaag aagaggcaat ccggattata gagactacag agctgaaaaa
     7261 tgacagagta ctggtagttt atcttccgga ttgtcatgaa agtcttgccg gtattatagc
     7321 aggcaggatc agggaaaaat atcacaggcc ggcctttgta ttgacgggcg gtgagacaag
     7381 tgcaaaagga agcggaagat caatagaaag ttactctatg tatgaagaac tggtaaaatg
     7441 tgcagacctg atgatacagt ttggaggtca tccgatggca gcaggtctgt ctatagaaga
     7501 aaaaaatata gaagaattcc ggagacgcct caatgtcaac
//
