## Sat Jun 29 07:43:35 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_014866025.1/GCA_014866025.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_014866025.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_014866025.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
NGKEMLHH_00002	1158607.UAU_05156	6.74e-14	82.4	COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HCUQ@91061|Bacilli,4B0JB@81852|Enterococcaceae	91061|Bacilli	S	Terminase RNAseH like domain	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_3C
NGKEMLHH_00003	226185.EF_2111	2.36e-90	288.0	2BKDY@1|root,32EUN@2|Bacteria,1TVYR@1239|Firmicutes,4IAKN@91061|Bacilli,4B5NA@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00015	1158612.I580_02499	3.64e-112	345.0	2CIPQ@1|root,303AV@2|Bacteria,1TU0J@1239|Firmicutes,4I7BT@91061|Bacilli,4B1TG@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00016	1158608.I583_02867	1.41e-22	97.8	29J3K@1|root,30612@2|Bacteria,1TZ0B@1239|Firmicutes,4I86S@91061|Bacilli,4B1TC@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00018	945021.TEH_08740	3.9e-35	156.0	COG3941@1|root,COG3953@1|root,COG5412@1|root,COG3941@2|Bacteria,COG3953@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HU9A@91061|Bacilli,4B0BD@81852|Enterococcaceae	91061|Bacilli	D	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00019	1158608.I583_02860	7.34e-107	324.0	2CIPP@1|root,305TM@2|Bacteria,1TYNJ@1239|Firmicutes,4I7T4@91061|Bacilli,4B03C@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00023	1158608.I583_02855	2.65e-110	357.0	COG0791@1|root,COG0791@2|Bacteria,1VABK@1239|Firmicutes,4HPQK@91061|Bacilli,4B188@81852|Enterococcaceae	91061|Bacilli	M	Bacteriophage peptidoglycan hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_5,CW_7,Glucosaminidase
NGKEMLHH_00026	1158608.I583_02852	2.19e-56	181.0	29J1S@1|root,305Z5@2|Bacteria,1TYXV@1239|Firmicutes,4I842@91061|Bacilli,4B1I3@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00030	33035.JPJF01000043_gene1000	4.39e-77	249.0	COG3344@1|root,COG3344@2|Bacteria,1V9Q7@1239|Firmicutes,25C60@186801|Clostridia	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
NGKEMLHH_00032	1336234.JAGN01000004_gene510	7.81e-10	59.3	2BFGJ@1|root,329AA@2|Bacteria,1U4E0@1239|Firmicutes,4HZZ9@91061|Bacilli	91061|Bacilli	S	Bacteriophage holin of superfamily 6 (Holin_LLH)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_6_1
NGKEMLHH_00033	78344.BIGA_0464	6.23e-06	50.1	COG3023@1|root,COG3757@1|root,COG3023@2|Bacteria,COG3757@2|Bacteria,2I2GA@201174|Actinobacteria,4D07F@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	CW_7,Glyco_hydro_25,LysM
NGKEMLHH_00034	877415.JNJQ01000013_gene314	1.9e-42	158.0	COG3757@1|root,COG3757@2|Bacteria,1V2DN@1239|Firmicutes,3VQGM@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25,LysM
NGKEMLHH_00036	1121115.AXVN01000058_gene2538	1.39e-62	192.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3Y068@572511|Blautia	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
NGKEMLHH_00037	1121115.AXVN01000058_gene2537	1.4e-40	133.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,3Y0KE@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
NGKEMLHH_00038	1121115.AXVN01000058_gene2536	1.91e-177	493.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,3XZIR@572511|Blautia	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
NGKEMLHH_00039	1121115.AXVN01000058_gene2535	1.01e-198	550.0	COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,24GN2@186801|Clostridia,3XZ9S@572511|Blautia	186801|Clostridia	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NGKEMLHH_00041	457412.RSAG_03239	0.0	1011.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3WHAV@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
NGKEMLHH_00042	457412.RSAG_03238	7.05e-312	848.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia,3WH2V@541000|Ruminococcaceae	186801|Clostridia	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
NGKEMLHH_00043	1121115.AXVN01000039_gene3303	7.16e-64	196.0	2F5U3@1|root,33YD0@2|Bacteria,1VVXV@1239|Firmicutes,250VV@186801|Clostridia,3Y21G@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00044	457412.RSAG_03236	0.0	1116.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGRP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NGKEMLHH_00045	457412.RSAG_03235	5.09e-304	828.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3WHGE@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NGKEMLHH_00046	1121115.AXVN01000039_gene3300	1.36e-303	831.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	xanP	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
NGKEMLHH_00047	457412.RSAG_03233	0.0	1153.0	COG1404@1|root,COG1404@2|Bacteria,1TQE0@1239|Firmicutes,25B1A@186801|Clostridia,3WI3C@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
NGKEMLHH_00048	457412.RSAG_03232	1.3e-194	538.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia,3WSCN@541000|Ruminococcaceae	186801|Clostridia	M	Prolipoprotein diacylglyceryl transferase	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
NGKEMLHH_00049	1121115.AXVN01000039_gene3297	4.93e-208	574.0	COG0010@1|root,COG0010@2|Bacteria,1V6Y2@1239|Firmicutes,24K01@186801|Clostridia,3Y08B@572511|Blautia	186801|Clostridia	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
NGKEMLHH_00050	457412.RSAG_03230	1.54e-190	530.0	COG3247@1|root,COG3247@2|Bacteria,1VAQW@1239|Firmicutes,24QIF@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
NGKEMLHH_00051	457412.RSAG_03229	1.75e-185	516.0	COG2755@1|root,COG2755@2|Bacteria,1VAV9@1239|Firmicutes	1239|Firmicutes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NGKEMLHH_00052	457412.RSAG_03228	1.41e-120	344.0	2DNPY@1|root,32YIB@2|Bacteria,1VHHM@1239|Firmicutes,24NJ3@186801|Clostridia,3WMNS@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4358)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4358
NGKEMLHH_00053	457412.RSAG_03227	0.0	909.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
NGKEMLHH_00054	457412.RSAG_03226	1.21e-284	778.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,3WINY@541000|Ruminococcaceae	186801|Clostridia	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
NGKEMLHH_00055	1121115.AXVN01000039_gene3291	6.65e-195	540.0	COG3279@1|root,COG3279@2|Bacteria,1V3QY@1239|Firmicutes,24IT9@186801|Clostridia,3Y1IK@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NGKEMLHH_00056	1121115.AXVN01000039_gene3290	2.33e-47	151.0	2E7JQ@1|root,3321V@2|Bacteria,1VH9B@1239|Firmicutes,24S3M@186801|Clostridia,3Y0WH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00057	1121115.AXVN01000039_gene3289	4.12e-139	392.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia,3Y0B0@572511|Blautia	186801|Clostridia	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
NGKEMLHH_00059	457412.RSAG_01684	8.39e-194	538.0	COG0395@1|root,COG0395@2|Bacteria,1TSGI@1239|Firmicutes,24BDH@186801|Clostridia,3WJKJ@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
NGKEMLHH_00060	457412.RSAG_01685	2.16e-208	577.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia,3WIYD@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport systems permease components	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
NGKEMLHH_00061	457412.RSAG_01686	1.45e-315	858.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia,3WMKQ@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_00062	457412.RSAG_01687	2.1e-128	365.0	2BXQ3@1|root,2ZCWE@2|Bacteria,1V3E8@1239|Firmicutes,24GTI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00063	457412.RSAG_01688	1.97e-206	573.0	COG2207@1|root,COG2207@2|Bacteria,1V0IW@1239|Firmicutes,24BME@186801|Clostridia,3WM59@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NGKEMLHH_00064	1121115.AXVN01000014_gene1195	2e-211	585.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3XZBQ@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
NGKEMLHH_00065	1121115.AXVN01000014_gene1194	6.35e-31	108.0	2AQUU@1|root,31G2Z@2|Bacteria,1UDXX@1239|Firmicutes,25IS7@186801|Clostridia,3Y251@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00066	457412.RSAG_01691	1.86e-285	780.0	COG0526@1|root,COG0526@2|Bacteria,1TSFN@1239|Firmicutes,24DAS@186801|Clostridia	186801|Clostridia	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
NGKEMLHH_00067	199310.c0318	1.84e-152	428.0	COG0698@1|root,COG0698@2|Bacteria,1MWIB@1224|Proteobacteria,1RPEG@1236|Gammaproteobacteria,3XMD5@561|Escherichia	1236|Gammaproteobacteria	G	Ribose-5-phosphate isomerase	Z012_03465	-	5.3.1.26,5.3.1.6	ko:K01808,ko:K01819	ko00030,ko00051,ko00052,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00052,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R03240,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3666,LacAB_rpiB
NGKEMLHH_00068	199310.c0319	8.33e-302	820.0	COG0823@1|root,COG0823@2|Bacteria,1MUK9@1224|Proteobacteria,1RNR8@1236|Gammaproteobacteria,3XQER@561|Escherichia	1236|Gammaproteobacteria	U	Oligogalacturonate lyase	ogl	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	Pectate_lyase22
NGKEMLHH_00069	199310.c0321	8.08e-192	532.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,1RMZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	iECIAI39_1322.ECIAI39_4739	adh_short,adh_short_C2
NGKEMLHH_00070	1196095.GAPWK_0011	1.41e-53	169.0	COG1917@1|root,COG1917@2|Bacteria,1RHSW@1224|Proteobacteria,1S6GC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Cupin 2, conserved barrel domain protein	kdgF	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NGKEMLHH_00071	199310.c0322	0.0	998.0	COG2211@1|root,COG2211@2|Bacteria,1MWT1@1224|Proteobacteria,1RMID@1236|Gammaproteobacteria,3XRJ4@561|Escherichia	1236|Gammaproteobacteria	G	MFS/sugar transport protein	melB1_1	-	-	ko:K03292,ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.5	-	-	MFS_2
NGKEMLHH_00072	199310.c0323	0.0	1495.0	COG5263@1|root,COG5263@2|Bacteria,1R42H@1224|Proteobacteria,1RY1A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Parallel beta-helix repeats	pelX	-	4.2.2.9	ko:K01731	ko00040,map00040	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Beta_helix
NGKEMLHH_00073	199310.c0325	6.37e-238	653.0	28ZV0@1|root,2ZMJN@2|Bacteria,1P7ZS@1224|Proteobacteria,1SU0X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00075	457412.RSAG_00644	1.2e-76	228.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,3WJE1@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
NGKEMLHH_00076	1121115.AXVN01000003_gene1628	1.18e-276	756.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3XYKK@572511|Blautia	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
NGKEMLHH_00077	1121115.AXVN01000003_gene1629	0.0	982.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3XZEG@572511|Blautia	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
NGKEMLHH_00078	1121115.AXVN01000003_gene1630	6.39e-150	422.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,3XZKT@572511|Blautia	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
NGKEMLHH_00079	1121115.AXVN01000003_gene1631	0.0	1171.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3XYWT@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NGKEMLHH_00080	1121115.AXVN01000003_gene1632	6.59e-296	806.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,3XZ3V@572511|Blautia	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NGKEMLHH_00081	1121115.AXVN01000099_gene786	0.0	1476.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,3XYPB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	tvaI	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
NGKEMLHH_00082	1121115.AXVN01000099_gene785	0.0	1140.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XYI4@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NGKEMLHH_00083	457412.RSAG_04578	3.04e-122	348.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,3WIX7@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NGKEMLHH_00084	457412.RSAG_03278	0.0	965.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,3WHDC@541000|Ruminococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
NGKEMLHH_00085	457412.RSAG_03277	0.0	979.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,3WH68@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
NGKEMLHH_00086	457412.RSAG_03276	2.36e-47	153.0	COG2919@1|root,COG2919@2|Bacteria,1VX29@1239|Firmicutes,252JU@186801|Clostridia,3WMKM@541000|Ruminococcaceae	186801|Clostridia	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
NGKEMLHH_00087	457412.RSAG_03275	2.05e-102	296.0	2EFTM@1|root,3095D@2|Bacteria,1U4G7@1239|Firmicutes,25JHX@186801|Clostridia,3WR8N@541000|Ruminococcaceae	186801|Clostridia	S	Spore cortex protein YabQ (Spore_YabQ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
NGKEMLHH_00088	457412.RSAG_03388	9.34e-225	619.0	COG0583@1|root,COG0583@2|Bacteria,1UYAI@1239|Firmicutes,24BA8@186801|Clostridia,3WKDZ@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NGKEMLHH_00089	457412.RSAG_03387	0.0	978.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3WGAY@541000|Ruminococcaceae	186801|Clostridia	G	Sugar (pentulose and hexulose) kinases	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
NGKEMLHH_00090	457412.RSAG_03386	0.0	1018.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3WGMD@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
NGKEMLHH_00091	457412.RSAG_03385	1.65e-147	415.0	28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,247W6@186801|Clostridia,3WIDK@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
NGKEMLHH_00092	1121115.AXVN01000030_gene3611	1.78e-203	563.0	COG2207@1|root,COG2207@2|Bacteria,1V48H@1239|Firmicutes,248BW@186801|Clostridia,3XZC4@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NGKEMLHH_00093	457412.RSAG_03383	2.1e-89	263.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia,3WK1B@541000|Ruminococcaceae	186801|Clostridia	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
NGKEMLHH_00094	1121115.AXVN01000030_gene3613	1.4e-208	586.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3XZAA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
NGKEMLHH_00095	1121115.AXVN01000006_gene2167	1.65e-200	554.0	COG1234@1|root,COG1234@2|Bacteria,1TPSW@1239|Firmicutes,249RR@186801|Clostridia,3XYRY@572511|Blautia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
NGKEMLHH_00096	1121115.AXVN01000006_gene2166	4.17e-157	440.0	COG1309@1|root,COG1309@2|Bacteria,1V3ZS@1239|Firmicutes,24H9U@186801|Clostridia,3XZV5@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NGKEMLHH_00097	1121115.AXVN01000006_gene2165	0.0	1299.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,3XYKA@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
NGKEMLHH_00098	1121115.AXVN01000006_gene2164	3.64e-273	797.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3XYKM@572511|Blautia	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
NGKEMLHH_00099	1121115.AXVN01000006_gene2163	2.08e-265	729.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3XYUT@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NGKEMLHH_00100	457412.RSAG_01845	2e-209	579.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WJ61@541000|Ruminococcaceae	186801|Clostridia	P	transport systems	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NGKEMLHH_00101	457412.RSAG_01844	4.13e-193	536.0	COG0395@1|root,COG0395@2|Bacteria,1TRD1@1239|Firmicutes,24BQQ@186801|Clostridia,3WNYS@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NGKEMLHH_00102	1121115.AXVN01000052_gene871	0.0	1105.0	COG2972@1|root,COG2972@2|Bacteria,1UYIY@1239|Firmicutes,24ACA@186801|Clostridia,3Y1EM@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,dCache_1
NGKEMLHH_00103	457412.RSAG_01842	0.0	966.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TRXY@1239|Firmicutes,24BYW@186801|Clostridia,3WN9A@541000|Ruminococcaceae	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NGKEMLHH_00104	457412.RSAG_01841	0.0	1416.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3WGZR@541000|Ruminococcaceae	186801|Clostridia	G	Hydrolase Family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NGKEMLHH_00105	457412.RSAG_01840	5.75e-244	671.0	2BP77@1|root,32HYI@2|Bacteria,1V84J@1239|Firmicutes,24JDS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00106	457412.RSAG_00606	1.14e-227	627.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,3WHWJ@541000|Ruminococcaceae	186801|Clostridia	P	Menaquinone biosynthesis	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,Phosphonate-bd,VitK2_biosynth
NGKEMLHH_00107	457412.RSAG_00607	1.15e-199	553.0	COG4733@1|root,COG4733@2|Bacteria,1UICW@1239|Firmicutes,25EHW@186801|Clostridia	186801|Clostridia	S	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
NGKEMLHH_00108	1121115.AXVN01000003_gene1589	2.32e-200	555.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3XZ53@572511|Blautia	186801|Clostridia	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
NGKEMLHH_00109	457412.RSAG_00609	3.83e-139	394.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,3WJ4I@541000|Ruminococcaceae	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
NGKEMLHH_00110	457412.RSAG_00610	1.25e-164	459.0	2C5Z2@1|root,32A20@2|Bacteria,1V5CS@1239|Firmicutes,24M7C@186801|Clostridia,3WP7T@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
NGKEMLHH_00111	457412.RSAG_00611	0.0	1280.0	COG1018@1|root,COG3894@1|root,COG1018@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3WI2J@541000|Ruminococcaceae	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
NGKEMLHH_00112	457412.RSAG_00612	2.8e-185	515.0	COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3WNXA@541000|Ruminococcaceae	186801|Clostridia	E	Pterin binding enzyme	acsE	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
NGKEMLHH_00113	457412.RSAG_00613	0.0	883.0	COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3WNR9@541000|Ruminococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsC	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
NGKEMLHH_00114	1121115.AXVN01000057_gene2531	1.98e-105	304.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,3Y02E@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
NGKEMLHH_00115	457412.RSAG_02835	6.47e-268	732.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,3WGIZ@541000|Ruminococcaceae	186801|Clostridia	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
NGKEMLHH_00116	457412.RSAG_02834	2.69e-79	235.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,3WK2T@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
NGKEMLHH_00117	1121115.AXVN01000057_gene2528	6.97e-144	405.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,24DN2@186801|Clostridia,3XZTN@572511|Blautia	186801|Clostridia	S	Psort location	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
NGKEMLHH_00118	1121115.AXVN01000057_gene2527	3.47e-109	315.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,3Y02K@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
NGKEMLHH_00120	1121115.AXVN01000057_gene2526	4.08e-157	442.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia,3XZEX@572511|Blautia	186801|Clostridia	K	COG COG1191 DNA-directed RNA polymerase specialized sigma subunit	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NGKEMLHH_00121	1121115.AXVN01000057_gene2525	3.68e-97	282.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,3Y0A1@572511|Blautia	186801|Clostridia	H	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
NGKEMLHH_00122	1121115.AXVN01000057_gene2524	2.76e-70	211.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,3Y0KP@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
NGKEMLHH_00123	1121115.AXVN01000057_gene2523	8.6e-258	714.0	COG0457@1|root,COG0457@2|Bacteria,1UI34@1239|Firmicutes,25F0K@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
NGKEMLHH_00124	1121115.AXVN01000057_gene2522	3.2e-27	99.0	2EGDA@1|root,33A54@2|Bacteria,1VKC8@1239|Firmicutes,258G8@186801|Clostridia,3Y0SU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00125	1121115.AXVN01000057_gene2521	7.41e-315	857.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3XZC1@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NGKEMLHH_00126	1121115.AXVN01000057_gene2520	1.66e-207	588.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,3XYIH@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
NGKEMLHH_00127	457412.RSAG_01620	1.75e-254	697.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,24A4E@186801|Clostridia,3WGJ9@541000|Ruminococcaceae	186801|Clostridia	C	Archaeal vacuolar-type H -ATPase subunit C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
NGKEMLHH_00128	457412.RSAG_01621	0.0	1266.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3WHFQ@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the V-ATPase 116 kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
NGKEMLHH_00129	1121115.AXVN01000018_gene60	1.37e-84	251.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,24RB6@186801|Clostridia,3Y0BA@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
NGKEMLHH_00130	1121115.AXVN01000018_gene59	5.62e-69	208.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,3Y07R@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
NGKEMLHH_00131	1121115.AXVN01000018_gene58	2.16e-129	368.0	COG1390@1|root,COG1390@2|Bacteria,1V7UJ@1239|Firmicutes,24ICM@186801|Clostridia,3Y0B1@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
NGKEMLHH_00132	457412.RSAG_01625	0.0	1168.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,3WGBK@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
NGKEMLHH_00133	1121115.AXVN01000018_gene56	0.0	913.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,3XZA3@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
NGKEMLHH_00134	1121115.AXVN01000018_gene55	3.03e-134	381.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,3XYVE@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
NGKEMLHH_00135	1235798.C817_00684	1.15e-16	95.5	COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia,27UY6@189330|Dorea	186801|Clostridia	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00138	1256908.HMPREF0373_02866	6.75e-86	272.0	COG0194@1|root,COG4502@1|root,COG0194@2|Bacteria,COG4502@2|Bacteria,1V87A@1239|Firmicutes,24SD2@186801|Clostridia	186801|Clostridia	F	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_kin,NT5C
NGKEMLHH_00148	1298920.KI911353_gene2736	2.49e-14	69.7	COG2002@1|root,COG2002@2|Bacteria,1UTXF@1239|Firmicutes,254RS@186801|Clostridia	186801|Clostridia	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
NGKEMLHH_00151	1408437.JNJN01000065_gene988	1.62e-27	108.0	2DMTR@1|root,32TMQ@2|Bacteria,1VCYA@1239|Firmicutes,24GYE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00152	1232453.BAIF02000099_gene3783	5.15e-33	115.0	2E7JQ@1|root,3321V@2|Bacteria,1VH9B@1239|Firmicutes,24S7B@186801|Clostridia,26C2I@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00155	411470.RUMGNA_03957	3.13e-148	440.0	COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,247MK@186801|Clostridia	186801|Clostridia	S	SPFH Band 7 PHB domain protein	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
NGKEMLHH_00168	1121115.AXVN01000054_gene1891	4.14e-31	110.0	2C1K5@1|root,3415T@2|Bacteria,1VY97@1239|Firmicutes,2522U@186801|Clostridia,3Y25V@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00169	457412.RSAG_02702	1.38e-227	627.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
NGKEMLHH_00170	1121115.AXVN01000054_gene1893	1.36e-174	488.0	2E77V@1|root,32VJN@2|Bacteria,1VA37@1239|Firmicutes,24P5M@186801|Clostridia,3Y1P9@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00171	457412.RSAG_02700	5.34e-108	311.0	2BWHH@1|root,33G8D@2|Bacteria,1VM1X@1239|Firmicutes,24W5T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00172	1121115.AXVN01000054_gene1895	2.36e-117	336.0	COG1595@1|root,COG1595@2|Bacteria,1VB8F@1239|Firmicutes,24PH6@186801|Clostridia,3Y1N5@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NGKEMLHH_00173	457412.RSAG_02698	8.72e-280	764.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3WHB1@541000|Ruminococcaceae	186801|Clostridia	J	Threonine alanine tRNA ligase second additional domain protein	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NGKEMLHH_00174	457412.RSAG_02697	1.73e-215	594.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia	186801|Clostridia	Q	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
NGKEMLHH_00175	1121115.AXVN01000054_gene1898	4.25e-271	743.0	COG3103@1|root,COG3103@2|Bacteria,1UG5Z@1239|Firmicutes,25NDX@186801|Clostridia,3Y048@572511|Blautia	186801|Clostridia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00176	457412.RSAG_02693	2.27e-122	350.0	COG3275@1|root,COG3275@2|Bacteria,1UJ12@1239|Firmicutes,24Q7D@186801|Clostridia,3WKDP@541000|Ruminococcaceae	186801|Clostridia	T	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS,ECF_trnsprt
NGKEMLHH_00177	1121115.AXVN01000049_gene1319	0.0	989.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,3XZB8@572511|Blautia	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
NGKEMLHH_00178	1121115.AXVN01000049_gene1318	1.08e-132	376.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,3XZUJ@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
NGKEMLHH_00179	1121115.AXVN01000049_gene1317	2.21e-231	638.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,3XZ38@572511|Blautia	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
NGKEMLHH_00180	457412.RSAG_02905	1.5e-174	489.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,3WG9T@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
NGKEMLHH_00181	1121115.AXVN01000049_gene1315	1.33e-144	408.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,3Y006@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
NGKEMLHH_00182	1121115.AXVN01000049_gene1314	2.01e-286	782.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,3XYNP@572511|Blautia	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NGKEMLHH_00183	1121115.AXVN01000049_gene1313	2.12e-179	500.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,3XYZ4@572511|Blautia	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
NGKEMLHH_00184	457412.RSAG_02909	2.24e-197	546.0	COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,25B80@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NGKEMLHH_00185	1121115.AXVN01000008_gene2661	0.0	1910.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3Y1FR@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_3
NGKEMLHH_00186	457412.RSAG_02531	3.75e-68	228.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WHQM@541000|Ruminococcaceae	186801|Clostridia	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_3
NGKEMLHH_00187	457412.RSAG_02530	8.23e-248	679.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,3WK39@541000|Ruminococcaceae	186801|Clostridia	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4,Peptidase_S9
NGKEMLHH_00188	1121115.AXVN01000008_gene2659	0.0	953.0	COG1020@1|root,COG1020@2|Bacteria,1TQP2@1239|Firmicutes,24AMK@186801|Clostridia,3Y0AJ@572511|Blautia	186801|Clostridia	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
NGKEMLHH_00189	1121115.AXVN01000008_gene2658	8.84e-43	140.0	2DP4E@1|root,330GX@2|Bacteria,1VEZ7@1239|Firmicutes,24SE1@186801|Clostridia,3Y0WR@572511|Blautia	186801|Clostridia	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
NGKEMLHH_00190	457412.RSAG_02527	0.0	1000.0	COG1022@1|root,COG1022@2|Bacteria,1V0YG@1239|Firmicutes,25E9H@186801|Clostridia,3WI3M@541000|Ruminococcaceae	186801|Clostridia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
NGKEMLHH_00191	457412.RSAG_02526	2.02e-137	388.0	COG1309@1|root,COG1309@2|Bacteria,1VGCX@1239|Firmicutes,24G4C@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NGKEMLHH_00192	1121115.AXVN01000048_gene1286	7.24e-151	428.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3Y2B1@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
NGKEMLHH_00193	1121115.AXVN01000048_gene1287	8.96e-308	841.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3Y064@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 10.00	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
NGKEMLHH_00194	1121115.AXVN01000048_gene1288	7.89e-245	672.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3XZ1P@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NGKEMLHH_00195	1121115.AXVN01000048_gene1289	1.66e-247	679.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3XZ61@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	appF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NGKEMLHH_00196	1121115.AXVN01000048_gene1290	0.0	1129.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,3Y0G8@572511|Blautia	186801|Clostridia	E	ABC transporter, substrate-binding protein, family 5	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
NGKEMLHH_00197	1121115.AXVN01000048_gene1291	4.57e-124	352.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24KU4@186801|Clostridia,3Y2AC@572511|Blautia	186801|Clostridia	I	NUDIX domain	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
NGKEMLHH_00198	1458462.JNLK01000001_gene436	1.07e-09	62.4	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27I9U@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
NGKEMLHH_00206	428127.EUBDOL_01507	4.56e-49	167.0	COG5377@1|root,COG5377@2|Bacteria,1TUI9@1239|Firmicutes,3VSAU@526524|Erysipelotrichia	526524|Erysipelotrichia	L	YqaJ-like viral recombinase domain	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
NGKEMLHH_00207	257314.LJ_0298	8.27e-07	57.8	2EHDI@1|root,33B5D@2|Bacteria,1VPW3@1239|Firmicutes,4HXEN@91061|Bacilli,3F6I3@33958|Lactobacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1351)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1351
NGKEMLHH_00208	1122173.AXVL01000068_gene1414	1.62e-67	215.0	COG3723@1|root,COG3723@2|Bacteria	2|Bacteria	L	DNA synthesis involved in double-strand break repair via homologous recombination	bet	-	-	ko:K07455	-	-	-	-	ko00000,ko03400	-	-	-	RecT
NGKEMLHH_00211	32057.KB217481_gene8515	4.92e-31	117.0	2EB1Y@1|root,3352R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00212	1121344.JHZO01000003_gene982	1.98e-27	112.0	2EE30@1|root,337XK@2|Bacteria,1UQJ4@1239|Firmicutes,258AT@186801|Clostridia,3WMIK@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00216	35241.Q9XJE8_BPTU2	1.3e-120	351.0	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae	10699|Siphoviridae	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00218	457412.RSAG_03473	0.0	1030.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WHR7@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase class I and II	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,HTH_3
NGKEMLHH_00219	1121115.AXVN01000130_gene182	5.09e-302	823.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3Y1H7@572511|Blautia	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	hacA	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
NGKEMLHH_00220	457412.RSAG_03475	2.28e-113	325.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3WIGV@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
NGKEMLHH_00221	457412.RSAG_03476	4.04e-304	828.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WG9G@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
NGKEMLHH_00222	1121115.AXVN01000130_gene185	7.39e-113	323.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3XZW2@572511|Blautia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
NGKEMLHH_00223	1121115.AXVN01000130_gene186	6.35e-300	816.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,3XYUY@572511|Blautia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08920	Metalloenzyme
NGKEMLHH_00224	457412.RSAG_03479	1.94e-104	301.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,3WK22@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
NGKEMLHH_00225	457412.RSAG_02168	2.74e-304	829.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,3WIJX@541000|Ruminococcaceae	186801|Clostridia	H	MoeA C-terminal region (domain IV)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
NGKEMLHH_00226	457412.RSAG_02167	1.25e-118	339.0	COG1763@1|root,COG1763@2|Bacteria,1VFA0@1239|Firmicutes,24IYN@186801|Clostridia,3WKCP@541000|Ruminococcaceae	186801|Clostridia	H	Molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
NGKEMLHH_00227	1121115.AXVN01000022_gene1763	5.3e-200	553.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia	186801|Clostridia	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
NGKEMLHH_00228	457412.RSAG_02165	5.1e-240	659.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,3WHWT@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
NGKEMLHH_00229	457412.RSAG_02164	4.16e-130	369.0	2A753@1|root,30W0Z@2|Bacteria,1TU7M@1239|Firmicutes,25N2S@186801|Clostridia,3WMN0@541000|Ruminococcaceae	186801|Clostridia	S	Toxin ToxN, type III toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	ToxN_toxin
NGKEMLHH_00230	1121115.AXVN01000022_gene1761	2.72e-145	410.0	COG0746@1|root,COG0746@2|Bacteria,1UQ1Y@1239|Firmicutes,257PR@186801|Clostridia,3Y0VI@572511|Blautia	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
NGKEMLHH_00231	457412.RSAG_02162	4.35e-143	404.0	2CKNK@1|root,306D0@2|Bacteria,1TZJW@1239|Firmicutes,2513T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00232	1121115.AXVN01000022_gene1759	3.22e-115	335.0	2F19F@1|root,33UAG@2|Bacteria,1VUX8@1239|Firmicutes,250KD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00233	1121115.AXVN01000022_gene1758	1.22e-68	207.0	COG4824@1|root,COG4824@2|Bacteria,1V934@1239|Firmicutes,24MXR@186801|Clostridia,3Y0R2@572511|Blautia	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
NGKEMLHH_00235	1121115.AXVN01000020_gene80	3.58e-65	209.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,24B76@186801|Clostridia	186801|Clostridia	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
NGKEMLHH_00236	457412.RSAG_00147	8.33e-120	343.0	COG4637@1|root,COG4637@2|Bacteria,1UZCB@1239|Firmicutes,248WE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
NGKEMLHH_00237	457412.RSAG_00145	0.0	1707.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WGM4@541000|Ruminococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
NGKEMLHH_00238	1121115.AXVN01000020_gene83	0.0	1285.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3XYSA@572511|Blautia	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
NGKEMLHH_00239	1121115.AXVN01000020_gene84	6.18e-158	447.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3XYZN@572511|Blautia	186801|Clostridia	H	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
NGKEMLHH_00240	457412.RSAG_00143	1.22e-46	157.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WGGD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
NGKEMLHH_00241	1121115.AXVN01000006_gene2154	0.0	976.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3XZIU@572511|Blautia	186801|Clostridia	H	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
NGKEMLHH_00242	457412.RSAG_00773	0.0	1160.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,3WGMT@541000|Ruminococcaceae	186801|Clostridia	L	helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NGKEMLHH_00243	1121115.AXVN01000006_gene2152	2.8e-135	382.0	COG2091@1|root,COG2091@2|Bacteria,1UFUD@1239|Firmicutes,25MRV@186801|Clostridia,3Y03Q@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
NGKEMLHH_00244	457412.RSAG_00771	1.89e-275	753.0	COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,24K83@186801|Clostridia,3WKY3@541000|Ruminococcaceae	186801|Clostridia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00245	457412.RSAG_00770	4.03e-240	659.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,3WGH3@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
NGKEMLHH_00246	1121115.AXVN01000006_gene2149	4.35e-120	343.0	2CEWW@1|root,3181X@2|Bacteria,1U7IP@1239|Firmicutes,2590I@186801|Clostridia,3Y0MY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06391	-	-	-	-	ko00000	-	-	-	Spore_III_AB
NGKEMLHH_00247	457412.RSAG_00768	9.49e-35	119.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,3WKGF@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
NGKEMLHH_00248	1121115.AXVN01000006_gene2147	1.25e-80	240.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia,3Y0FF@572511|Blautia	186801|Clostridia	S	COG NOG13205 non supervised orthologous group	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
NGKEMLHH_00249	622312.ROSEINA2194_03113	6.49e-290	793.0	28ISJ@1|root,2Z8RQ@2|Bacteria,1TRGC@1239|Firmicutes,24CC6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00250	622312.ROSEINA2194_03112	0.0	974.0	COG0631@1|root,COG0631@2|Bacteria,1TQWN@1239|Firmicutes,247KV@186801|Clostridia	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
NGKEMLHH_00251	622312.ROSEINA2194_03111	3.69e-193	536.0	COG0631@1|root,COG0631@2|Bacteria,1V094@1239|Firmicutes,24N9G@186801|Clostridia	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2,SpoIIE
NGKEMLHH_00252	622312.ROSEINA2194_03110	3.47e-124	353.0	COG1716@1|root,COG1716@2|Bacteria,1UZ57@1239|Firmicutes,24PC6@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
NGKEMLHH_00253	622312.ROSEINA2194_03109	8.09e-128	363.0	COG1716@1|root,COG1716@2|Bacteria,1VFJ4@1239|Firmicutes,24Q0H@186801|Clostridia	186801|Clostridia	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
NGKEMLHH_00254	622312.ROSEINA2194_03108	7.76e-89	261.0	COG0484@1|root,COG0484@2|Bacteria,1VAWE@1239|Firmicutes	1239|Firmicutes	O	Molecular chaperone	dnaJ3	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
NGKEMLHH_00255	622312.ROSEINA2194_03107	4.14e-94	275.0	2AGPY@1|root,316XK@2|Bacteria,1V241@1239|Firmicutes,24GUS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00256	622312.ROSEINA2194_03106	7.06e-96	279.0	2AGPY@1|root,309PS@2|Bacteria,1V64Q@1239|Firmicutes,24FXN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00257	622312.ROSEINA2194_03105	0.0	959.0	2C1IS@1|root,2Z86T@2|Bacteria,1TQRA@1239|Firmicutes,247QX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00258	457412.RSAG_03244	3.43e-101	293.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,3WJ32@541000|Ruminococcaceae	186801|Clostridia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
NGKEMLHH_00259	1121115.AXVN01000058_gene2540	3.05e-57	177.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,3Y0A3@572511|Blautia	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
NGKEMLHH_00260	1121115.AXVN01000058_gene2541	0.0	1304.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,3XYI8@572511|Blautia	186801|Clostridia	T	signaling protein consisting of a modified GGDEF domain and a DHH domain	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
NGKEMLHH_00261	1121115.AXVN01000058_gene2542	2.09e-95	278.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3XZYF@572511|Blautia	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
NGKEMLHH_00262	1121115.AXVN01000058_gene2543	2.12e-310	847.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3XYP7@572511|Blautia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
NGKEMLHH_00263	457412.RSAG_03250	1.01e-99	290.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24VXI@186801|Clostridia,3WRY4@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NGKEMLHH_00264	1121115.AXVN01000058_gene2545	3.78e-20	81.6	COG1148@1|root,COG1148@2|Bacteria,1UI0M@1239|Firmicutes,25E99@186801|Clostridia,3Y0Q0@572511|Blautia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
NGKEMLHH_00265	457412.RSAG_03253	2.44e-286	781.0	COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia,3WSBG@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
NGKEMLHH_00266	457412.RSAG_03254	0.0	985.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3WSIS@541000|Ruminococcaceae	186801|Clostridia	S	transport systems ATPase components	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
NGKEMLHH_00267	457412.RSAG_03255	6.34e-254	697.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3WHQZ@541000|Ruminococcaceae	186801|Clostridia	S	transport system permease	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NGKEMLHH_00268	457412.RSAG_03256	1.17e-221	612.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,3WIJ5@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NGKEMLHH_00269	1121115.AXVN01000058_gene2550	1.42e-39	131.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia,3Y0MQ@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
NGKEMLHH_00270	457412.RSAG_03258	3.26e-173	483.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia	186801|Clostridia	NOT	Negative regulator of genetic competence	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
NGKEMLHH_00271	1121115.AXVN01000058_gene2552	1.72e-40	133.0	2EHIK@1|root,3498W@2|Bacteria,1VYKX@1239|Firmicutes,252YA@186801|Clostridia,3Y0QM@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00272	1121115.AXVN01000058_gene2553	0.0	1064.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia,3XZGJ@572511|Blautia	186801|Clostridia	S	Glyco_18	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
NGKEMLHH_00273	457412.RSAG_03261	1.05e-156	440.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,3WIGM@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NGKEMLHH_00274	457412.RSAG_04579	0.0	1315.0	COG5427@1|root,COG5427@2|Bacteria,1UXXM@1239|Firmicutes,24EF9@186801|Clostridia,3WHFN@541000|Ruminococcaceae	186801|Clostridia	M	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00275	457412.RSAG_03264	0.0	1477.0	COG5427@1|root,COG5427@2|Bacteria,1UY7V@1239|Firmicutes,24BA0@186801|Clostridia,3WHM2@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
NGKEMLHH_00276	1121115.AXVN01000079_gene2733	2.02e-120	357.0	COG0772@1|root,COG0772@2|Bacteria,1TRIP@1239|Firmicutes,258QF@186801|Clostridia,3Y1Z2@572511|Blautia	186801|Clostridia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00277	457412.RSAG_02064	2.69e-190	529.0	COG5464@1|root,COG5464@2|Bacteria,1V2ZE@1239|Firmicutes,25DF2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
NGKEMLHH_00278	1121115.AXVN01000133_gene740	8.93e-130	369.0	COG1595@1|root,COG1595@2|Bacteria,1V9GU@1239|Firmicutes,24KTH@186801|Clostridia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NGKEMLHH_00279	1121115.AXVN01000133_gene741	1.53e-235	650.0	29WCT@1|root,30HYG@2|Bacteria,1TYPB@1239|Firmicutes,258RC@186801|Clostridia,3Y1W1@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NGKEMLHH_00281	1121115.AXVN01000133_gene742	1.56e-152	429.0	COG0745@1|root,COG0745@2|Bacteria,1TT73@1239|Firmicutes,2487E@186801|Clostridia,3Y0AH@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_00282	1121115.AXVN01000133_gene743	3.97e-294	804.0	COG0642@1|root,COG2205@2|Bacteria,1TRD2@1239|Firmicutes,247M3@186801|Clostridia,3Y0A6@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NGKEMLHH_00283	1121115.AXVN01000133_gene744	6.19e-311	848.0	2CGG8@1|root,30FQ1@2|Bacteria,1UEDU@1239|Firmicutes,25JA2@186801|Clostridia,3Y0ZN@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00285	411473.RUMCAL_00166	4.03e-113	336.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WHQU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
NGKEMLHH_00286	877424.ATWC01000025_gene2150	3.14e-144	414.0	COG3617@1|root,COG3617@2|Bacteria,1TS1A@1239|Firmicutes,2486G@186801|Clostridia,27KZM@186928|unclassified Lachnospiraceae	186801|Clostridia	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
NGKEMLHH_00287	877411.JMMA01000002_gene617	3.72e-182	528.0	COG1961@1|root,COG1961@2|Bacteria,1TRVQ@1239|Firmicutes,249AZ@186801|Clostridia,3WGI0@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_00288	742765.HMPREF9457_03097	1.21e-37	132.0	COG1595@1|root,COG1595@2|Bacteria,1U7K2@1239|Firmicutes,24KJ3@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
NGKEMLHH_00289	877411.JMMA01000002_gene1631	1.6e-108	323.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3WHDX@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NGKEMLHH_00291	457412.RSAG_01534	2.99e-307	838.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia,3WJP9@541000|Ruminococcaceae	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_00292	457412.RSAG_01533	4.9e-206	570.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WJ61@541000|Ruminococcaceae	186801|Clostridia	P	transport systems	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NGKEMLHH_00293	457412.RSAG_01532	6.29e-186	518.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3WIS9@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NGKEMLHH_00294	457412.RSAG_01531	6.56e-187	520.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V27N@1239|Firmicutes,24EUU@186801|Clostridia,3WPI2@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
NGKEMLHH_00295	457412.RSAG_01530	0.0	1054.0	COG2972@1|root,COG2972@2|Bacteria,1V4G9@1239|Firmicutes,24IA9@186801|Clostridia,3WP6J@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NGKEMLHH_00296	457412.RSAG_01529	0.0	1424.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3WH8U@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NGKEMLHH_00297	658088.HMPREF0987_01141	0.0	1275.0	COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,27JEU@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DNA polymerase A domain	-	-	2.7.7.7	ko:K02334	-	-	-	-	ko00000,ko01000	-	-	-	DNA_pol_A
NGKEMLHH_00298	658088.HMPREF0987_01142	2.09e-55	173.0	2BRMM@1|root,32KM1@2|Bacteria,1USAB@1239|Firmicutes,25A9M@186801|Clostridia,27PYJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	NUMOD4 motif	-	-	-	-	-	-	-	-	-	-	-	-	NUMOD4
NGKEMLHH_00299	658655.HMPREF0988_00565	6.86e-126	358.0	28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,249U3@186801|Clostridia,27KN8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF2815)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2815
NGKEMLHH_00300	658088.HMPREF0987_01144	6.77e-269	736.0	COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,27IAF@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Protein of unknown function (DUF2800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2800
NGKEMLHH_00301	658088.HMPREF0987_01145	2.62e-55	173.0	2E6I4@1|root,3315A@2|Bacteria,1VBDX@1239|Firmicutes,25HM7@186801|Clostridia,27PTN@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00302	658088.HMPREF0987_01146	3.55e-39	130.0	2FEN7@1|root,346MK@2|Bacteria,1W0Z7@1239|Firmicutes,254DY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00303	658088.HMPREF0987_01147	3.22e-90	264.0	2CGYE@1|root,32T72@2|Bacteria,1VBA8@1239|Firmicutes,24K9V@186801|Clostridia,27PX4@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00304	658088.HMPREF0987_01148	5.61e-71	214.0	COG2378@1|root,COG2378@2|Bacteria,1V7YK@1239|Firmicutes,24HGV@186801|Clostridia,27MX5@186928|unclassified Lachnospiraceae	186801|Clostridia	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11
NGKEMLHH_00306	1121115.AXVN01000046_gene2947	3.88e-73	219.0	COG1937@1|root,COG1937@2|Bacteria,1VA7S@1239|Firmicutes,24NNH@186801|Clostridia,3Y061@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NGKEMLHH_00307	1121115.AXVN01000046_gene2948	7.08e-49	155.0	2ES6S@1|root,33JRI@2|Bacteria,1VQGH@1239|Firmicutes,24WUX@186801|Clostridia,3Y0HU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00308	1121115.AXVN01000046_gene2949	4.41e-131	372.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,3XZCM@572511|Blautia	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NGKEMLHH_00309	1121115.AXVN01000046_gene2950	0.0	887.0	COG4213@1|root,COG4213@2|Bacteria,1VR5M@1239|Firmicutes,24ZY3@186801|Clostridia,3Y037@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NGKEMLHH_00310	1121115.AXVN01000046_gene2951	6.36e-134	380.0	COG2378@1|root,COG2378@2|Bacteria,1UH6Q@1239|Firmicutes,2504G@186801|Clostridia,3Y0EB@572511|Blautia	186801|Clostridia	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00311	457412.RSAG_02878	9.84e-180	499.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,24A80@186801|Clostridia,3WHHU@541000|Ruminococcaceae	186801|Clostridia	S	glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
NGKEMLHH_00312	457412.RSAG_02877	0.0	898.0	COG0769@1|root,COG0769@2|Bacteria,1UHY9@1239|Firmicutes,25E6X@186801|Clostridia,3WHF5@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
NGKEMLHH_00313	457412.RSAG_02876	4.99e-221	608.0	COG0584@1|root,COG0584@2|Bacteria,1TUUB@1239|Firmicutes,259V0@186801|Clostridia,3WQRJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00314	1121115.AXVN01000046_gene2955	1.28e-115	332.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,3XZ2H@572511|Blautia	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
NGKEMLHH_00315	457412.RSAG_02598	4.86e-280	765.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,3WIXP@541000|Ruminococcaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NGKEMLHH_00316	1121115.AXVN01000089_gene2819	0.0	1246.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,3XYQ1@572511|Blautia	186801|Clostridia	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
NGKEMLHH_00317	1121115.AXVN01000089_gene2818	3.22e-207	574.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia,3Y072@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NGKEMLHH_00318	1121115.AXVN01000089_gene2817	0.0	1885.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3Y1DS@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
NGKEMLHH_00319	1121115.AXVN01000089_gene2816	2.87e-195	555.0	COG0737@1|root,COG1653@1|root,COG0737@2|Bacteria,COG1653@2|Bacteria,1U6YH@1239|Firmicutes,24ENB@186801|Clostridia,3Y15J@572511|Blautia	186801|Clostridia	FG	ABC transporter substrate-binding protein	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_00320	457412.RSAG_02240	1.74e-310	845.0	COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes	1239|Firmicutes	S	Aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
NGKEMLHH_00321	457412.RSAG_02239	2.2e-201	562.0	COG5523@1|root,COG5523@2|Bacteria,1TTE0@1239|Firmicutes,25M7C@186801|Clostridia,3WMQF@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
NGKEMLHH_00322	1121115.AXVN01000028_gene200	1.63e-280	768.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3XYJN@572511|Blautia	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
NGKEMLHH_00323	1121115.AXVN01000028_gene199	4.09e-291	795.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3XYWS@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
NGKEMLHH_00324	1121115.AXVN01000028_gene198	7.24e-102	295.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,3XZTJ@572511|Blautia	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
NGKEMLHH_00325	1121115.AXVN01000028_gene197	3.29e-234	644.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,3XZ5R@572511|Blautia	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NGKEMLHH_00326	1121115.AXVN01000028_gene195	7.79e-203	561.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24B81@186801|Clostridia,3XZ57@572511|Blautia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF_2	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
NGKEMLHH_00327	1121115.AXVN01000024_gene315	1.97e-26	100.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,3XZET@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
NGKEMLHH_00328	457412.RSAG_02173	0.0	1222.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3WGG2@541000|Ruminococcaceae	186801|Clostridia	C	NADH ubiquinone oxidoreductase	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
NGKEMLHH_00329	1121115.AXVN01000024_gene317	0.0	1856.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,3XYRD@572511|Blautia	186801|Clostridia	C	Molydopterin dinucleotide binding domain	fdhA2	-	1.17.1.11,1.17.1.9	ko:K00123,ko:K22341	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
NGKEMLHH_00330	457412.RSAG_02171	0.0	1128.0	COG2221@1|root,COG4624@1|root,COG2221@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,24YQ5@186801|Clostridia,3WGXS@541000|Ruminococcaceae	186801|Clostridia	C	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,PAS
NGKEMLHH_00331	457412.RSAG_02170	1.81e-292	798.0	COG2208@1|root,COG2208@2|Bacteria,1TQUC@1239|Firmicutes,248FZ@186801|Clostridia,3WGNY@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
NGKEMLHH_00332	1121115.AXVN01000028_gene225	6.9e-41	134.0	COG0425@1|root,COG0425@2|Bacteria,1VKDK@1239|Firmicutes,24RK7@186801|Clostridia,3Y1ZM@572511|Blautia	186801|Clostridia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
NGKEMLHH_00333	1121115.AXVN01000028_gene226	5.75e-52	163.0	2DKC3@1|root,30954@2|Bacteria,1U4FV@1239|Firmicutes,258BV@186801|Clostridia,3Y1WH@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
NGKEMLHH_00336	457412.RSAG_02276	1.82e-138	392.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,3WI1Y@541000|Ruminococcaceae	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
NGKEMLHH_00337	1280698.AUJS01000046_gene562	6.05e-176	495.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,27V3G@189330|Dorea	186801|Clostridia	G	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NGKEMLHH_00338	478749.BRYFOR_08417	1.1e-55	185.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia	186801|Clostridia	EJ	L-asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
NGKEMLHH_00339	1121115.AXVN01000116_gene2328	6.85e-177	501.0	COG1865@1|root,COG1865@2|Bacteria,1TQHV@1239|Firmicutes,24AA4@186801|Clostridia,3Y0CC@572511|Blautia	186801|Clostridia	S	Adenosylcobinamide amidohydrolase	cbiZ	-	-	-	-	-	-	-	-	-	-	-	CbiZ
NGKEMLHH_00340	1123075.AUDP01000028_gene1946	2.97e-19	92.4	COG4886@1|root,COG4886@2|Bacteria,1V44C@1239|Firmicutes,25EA1@186801|Clostridia	186801|Clostridia	M	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,LRR_5
NGKEMLHH_00341	457412.RSAG_01929	6.15e-144	415.0	COG5464@1|root,COG5464@2|Bacteria,1TUFY@1239|Firmicutes,259KT@186801|Clostridia,3WQBQ@541000|Ruminococcaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00343	1121115.AXVN01000030_gene3637	4.57e-271	744.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3XZ8E@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	macB2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NGKEMLHH_00344	457412.RSAG_03345	8.92e-288	803.0	COG0845@1|root,COG0845@2|Bacteria,1UZA4@1239|Firmicutes,24BV0@186801|Clostridia,3WJXH@541000|Ruminococcaceae	186801|Clostridia	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NGKEMLHH_00345	1121115.AXVN01000030_gene3639	2.04e-169	473.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3XYST@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_00346	1121115.AXVN01000030_gene3640	0.0	895.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3XZF0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
NGKEMLHH_00347	457412.RSAG_03342	0.0	1118.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia,3WHYM@541000|Ruminococcaceae	186801|Clostridia	S	Predicted ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
NGKEMLHH_00348	1121115.AXVN01000055_gene1906	1.94e-99	290.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,3XZTG@572511|Blautia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
NGKEMLHH_00349	1121115.AXVN01000055_gene1905	4.2e-240	660.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,3XZC5@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
NGKEMLHH_00350	1121115.AXVN01000055_gene1904	2.46e-81	241.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia,3Y06J@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00351	457412.RSAG_03174	3.98e-188	523.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
NGKEMLHH_00352	1121115.AXVN01000055_gene1902	1.17e-245	674.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3XYMZ@572511|Blautia	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
NGKEMLHH_00353	1121115.AXVN01000055_gene1901	1.15e-150	432.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3XZEQ@572511|Blautia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
NGKEMLHH_00354	1121115.AXVN01000055_gene1900	4.78e-90	265.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,3Y0IA@572511|Blautia	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
NGKEMLHH_00355	1121115.AXVN01000031_gene354	1.82e-179	500.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,3XYZF@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
NGKEMLHH_00356	1121115.AXVN01000031_gene353	5.03e-148	417.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,3XZZU@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NGKEMLHH_00357	457412.RSAG_03180	0.0	892.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3WGPB@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NGKEMLHH_00358	457412.RSAG_03181	1.65e-240	660.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3WH67@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
NGKEMLHH_00359	457412.RSAG_03182	0.0	2269.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WGNQ@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
NGKEMLHH_00360	1121115.AXVN01000031_gene349	2.81e-194	539.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,3XZD5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
NGKEMLHH_00361	457412.RSAG_03184	4.54e-201	556.0	COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,24D7F@186801|Clostridia,3WIPT@541000|Ruminococcaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
NGKEMLHH_00362	457412.RSAG_03185	5.14e-287	785.0	2EVYD@1|root,33PC0@2|Bacteria,1VUAR@1239|Firmicutes,24ZRA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00363	1121115.AXVN01000031_gene346	2.83e-174	484.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,3XYMH@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
NGKEMLHH_00364	1121115.AXVN01000031_gene345	6.72e-205	566.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia,3XZSF@572511|Blautia	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
NGKEMLHH_00365	1121115.AXVN01000031_gene344	6.4e-174	484.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia,3XZPR@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
NGKEMLHH_00366	1121115.AXVN01000031_gene343	0.0	970.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia,3XYZD@572511|Blautia	186801|Clostridia	T	COG COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NGKEMLHH_00367	203119.Cthe_1264	3.37e-26	119.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WGNQ@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
NGKEMLHH_00371	1232447.BAHW02000015_gene1077	8.18e-92	295.0	28WWQ@1|root,2ZIVY@2|Bacteria,1W3H8@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00374	457412.RSAG_02194	6.93e-79	235.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3WKJ7@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
NGKEMLHH_00375	1121115.AXVN01000146_gene775	7.72e-165	461.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,3Y00D@572511|Blautia	186801|Clostridia	F	Phosphorylase superfamily	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
NGKEMLHH_00376	1121115.AXVN01000146_gene774	1.2e-162	457.0	COG0568@1|root,COG0568@2|Bacteria,1VJ02@1239|Firmicutes,24RNB@186801|Clostridia,3Y0EP@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
NGKEMLHH_00384	1121115.AXVN01000146_gene773	2.48e-115	330.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,3Y05G@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NGKEMLHH_00385	457412.RSAG_02198	3.76e-134	380.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,3WIUM@541000|Ruminococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
NGKEMLHH_00386	1121115.AXVN01000146_gene771	2.72e-283	773.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,3XYQ3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
NGKEMLHH_00387	1121115.AXVN01000146_gene770	7.16e-132	373.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,3XZ4B@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NGKEMLHH_00388	1121115.AXVN01000198_gene2447	6.29e-71	213.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia,3Y0GN@572511|Blautia	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
NGKEMLHH_00389	1121115.AXVN01000198_gene2446	4.86e-33	114.0	2FGU2@1|root,348PD@2|Bacteria,1VZBU@1239|Firmicutes,252UE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00390	1121115.AXVN01000136_gene976	7.87e-126	357.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,3Y0NR@572511|Blautia	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NGKEMLHH_00391	1121115.AXVN01000136_gene977	1.2e-95	278.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia,3Y0F5@572511|Blautia	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00392	1121115.AXVN01000136_gene978	3.09e-208	575.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia,3XZ5E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00393	1121115.AXVN01000136_gene979	1.02e-146	414.0	COG0484@1|root,COG0484@2|Bacteria,1UWW2@1239|Firmicutes,25CGC@186801|Clostridia,3XZTD@572511|Blautia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
NGKEMLHH_00394	1121115.AXVN01000136_gene980	2e-239	657.0	COG1712@1|root,COG1712@2|Bacteria,1TQ4R@1239|Firmicutes,2499V@186801|Clostridia,3XYQU@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate	ddh	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C,DapB_N
NGKEMLHH_00395	1121115.AXVN01000136_gene981	4.4e-258	718.0	COG5263@1|root,COG5263@2|Bacteria,1UK2Z@1239|Firmicutes,24XW0@186801|Clostridia,3XZWP@572511|Blautia	186801|Clostridia	S	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
NGKEMLHH_00396	457412.RSAG_01788	3.22e-205	583.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,3WHR8@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
NGKEMLHH_00397	1121115.AXVN01000101_gene814	0.0	1169.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XZ2D@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NGKEMLHH_00398	1121115.AXVN01000101_gene815	0.0	1321.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XYTY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NGKEMLHH_00399	457412.RSAG_02473	7.17e-104	300.0	COG1846@1|root,COG1846@2|Bacteria,1VFS1@1239|Firmicutes,24QXV@186801|Clostridia,3WRVD@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NGKEMLHH_00400	1121115.AXVN01000101_gene817	2.6e-208	576.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,249AX@186801|Clostridia,3Y0AZ@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NGKEMLHH_00401	457412.RSAG_02475	0.0	883.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NGKEMLHH_00403	411469.EUBHAL_00424	4.71e-73	219.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,25UQU@186806|Eubacteriaceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
NGKEMLHH_00404	1232447.BAHW02000027_gene2099	0.0	1341.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,267MD@186813|unclassified Clostridiales	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
NGKEMLHH_00405	1280698.AUJS01000017_gene1778	6.08e-194	539.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,248SU@186801|Clostridia,27W0C@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00406	1121333.JMLH01000056_gene1761	1.44e-42	139.0	2CDEH@1|root,32RXK@2|Bacteria,1VA17@1239|Firmicutes,3VR9H@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Maff2 family	-	-	-	-	-	-	-	-	-	-	-	-	Maff2
NGKEMLHH_00407	1121333.JMLH01000056_gene1760	1.36e-116	348.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,3VP0A@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf,TraG-D_C
NGKEMLHH_00408	457412.RSAG_03265	1.41e-265	727.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NGKEMLHH_00409	457412.RSAG_03266	2.54e-244	672.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3WGIY@541000|Ruminococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
NGKEMLHH_00410	1121115.AXVN01000135_gene972	9.72e-103	296.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3XZXS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
NGKEMLHH_00411	457412.RSAG_03268	3.12e-120	342.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,3WRVA@541000|Ruminococcaceae	186801|Clostridia	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
NGKEMLHH_00412	1121115.AXVN01000135_gene969	0.0	988.0	COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,25E98@186801|Clostridia,3XZ9B@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
NGKEMLHH_00413	457412.RSAG_03270	0.0	867.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WGBR@541000|Ruminococcaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
NGKEMLHH_00414	1121115.AXVN01000029_gene647	2.82e-260	724.0	2ENTE@1|root,33GEK@2|Bacteria,1VSB4@1239|Firmicutes,24YR1@186801|Clostridia,3XZII@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00415	1121115.AXVN01000029_gene646	5.93e-73	219.0	2E3KV@1|root,32YJ5@2|Bacteria,1VEHD@1239|Firmicutes,24RP3@186801|Clostridia,3Y0RE@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
NGKEMLHH_00416	1121115.AXVN01000029_gene645	1.83e-20	81.6	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,3Y0JJ@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score 8.82	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
NGKEMLHH_00417	1121115.AXVN01000029_gene644	0.0	943.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,3XZ42@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
NGKEMLHH_00418	1121115.AXVN01000029_gene643	0.0	1439.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,3XYSY@572511|Blautia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
NGKEMLHH_00420	457412.RSAG_03191	2.41e-149	420.0	COG0461@1|root,COG0461@2|Bacteria,1V23H@1239|Firmicutes,24FTS@186801|Clostridia,3WIVV@541000|Ruminococcaceae	186801|Clostridia	F	Orotate phosphoribosyltransferase	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
NGKEMLHH_00421	1121115.AXVN01000031_gene340	1.67e-74	223.0	COG1115@1|root,COG1115@2|Bacteria,1VUZR@1239|Firmicutes,25092@186801|Clostridia	186801|Clostridia	E	Sodium:alanine symporter family	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ala_symp
NGKEMLHH_00422	1121115.AXVN01000031_gene339	0.0	887.0	COG2942@1|root,COG2942@2|Bacteria,1UQC2@1239|Firmicutes,24D2T@186801|Clostridia,3Y1CF@572511|Blautia	186801|Clostridia	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
NGKEMLHH_00423	1121115.AXVN01000031_gene338	1.23e-217	604.0	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NGKEMLHH_00424	397291.C804_00692	5.91e-46	161.0	COG0582@1|root,COG0582@2|Bacteria,1UXHG@1239|Firmicutes,25ME8@186801|Clostridia,27SHE@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NGKEMLHH_00425	1121115.AXVN01000031_gene336	3.8e-293	800.0	29WCT@1|root,30HYG@2|Bacteria,1TYPB@1239|Firmicutes,258RC@186801|Clostridia,3Y1W1@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NGKEMLHH_00426	1121115.AXVN01000031_gene335	6.81e-60	187.0	COG1595@1|root,COG1595@2|Bacteria,1V1JW@1239|Firmicutes,24FYN@186801|Clostridia,3Y0F3@572511|Blautia	186801|Clostridia	K	DNA-directed RNA polymerase sigma subunit (RpoE,sigma24)	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NGKEMLHH_00427	1121115.AXVN01000104_gene848	1.26e-75	225.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,3Y1XY@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
NGKEMLHH_00428	1121115.AXVN01000104_gene849	0.0	1122.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,3Y0UM@572511|Blautia	186801|Clostridia	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
NGKEMLHH_00429	457412.RSAG_01514	5.13e-245	674.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WSP6@541000|Ruminococcaceae	186801|Clostridia	E	ATPases associated with a variety of cellular activities	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
NGKEMLHH_00430	457412.RSAG_01515	6.02e-182	508.0	COG4208@1|root,COG4208@2|Bacteria,1TS3N@1239|Firmicutes,24C3X@186801|Clostridia,3WHKV@541000|Ruminococcaceae	186801|Clostridia	P	sulfate ABC transporter	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
NGKEMLHH_00431	457412.RSAG_01516	2.19e-186	519.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,24ACM@186801|Clostridia,3WIAX@541000|Ruminococcaceae	186801|Clostridia	P	Sulfate ABC transporter, permease protein CysT	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
NGKEMLHH_00432	457412.RSAG_01517	4.4e-245	672.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia,3WGXR@541000|Ruminococcaceae	186801|Clostridia	P	Extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
NGKEMLHH_00433	1121115.AXVN01000104_gene854	2.37e-110	317.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3Y07W@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
NGKEMLHH_00434	1121864.OMO_01641	2.34e-85	251.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NGKEMLHH_00435	1121864.OMO_01640	0.0	1270.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,4HAS9@91061|Bacilli,4B0A2@81852|Enterococcaceae	91061|Bacilli	J	Elongation factor G, domain IV	tetM	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
NGKEMLHH_00436	1121864.OMO_01639	6.96e-116	332.0	COG1191@1|root,COG1191@2|Bacteria,1V1GF@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score	XK26_06155	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
NGKEMLHH_00437	411490.ANACAC_02334	8.18e-94	275.0	COG1595@1|root,COG1595@2|Bacteria,1UYSW@1239|Firmicutes,24CRZ@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
NGKEMLHH_00438	1232452.BAIB02000011_gene2185	4.37e-32	111.0	2EF0F@1|root,338TI@2|Bacteria,1VHS7@1239|Firmicutes,24TZ5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00439	411490.ANACAC_02332	5.36e-247	678.0	COG0468@1|root,COG0468@2|Bacteria,1V9SB@1239|Firmicutes,25E2S@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
NGKEMLHH_00440	1121115.AXVN01000026_gene983	1.2e-100	303.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3XZ33@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NGKEMLHH_00441	1121115.AXVN01000026_gene984	1.21e-53	168.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NGKEMLHH_00442	1121115.AXVN01000026_gene985	0.0	1016.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3XZ65@572511|Blautia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
NGKEMLHH_00443	1121115.AXVN01000026_gene986	5.25e-200	555.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,248N9@186801|Clostridia,3XYTV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NGKEMLHH_00444	1121115.AXVN01000026_gene987	0.0	1162.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,3XZ10@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
NGKEMLHH_00445	457412.RSAG_00502	3.06e-300	819.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,3WIN0@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
NGKEMLHH_00446	1121115.AXVN01000026_gene989	3.96e-156	447.0	2CAM6@1|root,33TP6@2|Bacteria,1VTBW@1239|Firmicutes,24Z6R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00447	457412.RSAG_00500	1.91e-151	426.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,3WITI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NGKEMLHH_00448	1121115.AXVN01000026_gene991	1.12e-168	473.0	COG1266@1|root,COG1266@2|Bacteria,1W749@1239|Firmicutes,25MB2@186801|Clostridia,3Y0CJ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Abi
NGKEMLHH_00449	1121115.AXVN01000026_gene992	2.53e-80	238.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia,3Y09K@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NGKEMLHH_00450	1121115.AXVN01000026_gene993	1.6e-215	595.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia,3XYHB@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	ytrB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_00451	457412.RSAG_00496	0.0	1318.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,24EMN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
NGKEMLHH_00452	1121115.AXVN01000026_gene995	1.32e-171	480.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,3XZSS@572511|Blautia	186801|Clostridia	J	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NGKEMLHH_00453	457412.RSAG_00494	3.53e-172	481.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
NGKEMLHH_00454	1121115.AXVN01000026_gene997	3.56e-193	539.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3XZ81@572511|Blautia	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
NGKEMLHH_00455	500632.CLONEX_01893	3.63e-81	243.0	2CUHA@1|root,2ZNG3@2|Bacteria,1V21P@1239|Firmicutes,24G2N@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00456	1235793.C809_01463	1.76e-20	82.4	2C7EF@1|root,33FU0@2|Bacteria,1VMPB@1239|Firmicutes,25PQ4@186801|Clostridia,27QDU@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00457	411459.RUMOBE_00663	7.04e-173	483.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,3XZBU@572511|Blautia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
NGKEMLHH_00458	500632.CLONEX_01890	2.17e-124	364.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
NGKEMLHH_00459	411459.RUMOBE_04160	7.27e-158	447.0	COG0583@1|root,COG0583@2|Bacteria,1V5MW@1239|Firmicutes,24J0X@186801|Clostridia,3Y0IH@572511|Blautia	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1
NGKEMLHH_00460	411459.RUMOBE_04159	2.62e-196	547.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZG8@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NGKEMLHH_00461	411459.RUMOBE_04158	1.42e-173	488.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZRV@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
NGKEMLHH_00462	411459.RUMOBE_04157	0.0	940.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3XZGV@572511|Blautia	186801|Clostridia	E	Psort location Cellwall, score	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NGKEMLHH_00463	411459.RUMOBE_04156	2.39e-151	430.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,24B9N@186801|Clostridia,3XZCY@572511|Blautia	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NGKEMLHH_00464	411459.RUMOBE_04155	9.82e-145	412.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24A3N@186801|Clostridia,3XZ3G@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NGKEMLHH_00465	411461.DORFOR_02067	2.7e-193	540.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia,27VKR@189330|Dorea	186801|Clostridia	EG	COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NGKEMLHH_00467	1121115.AXVN01000128_gene273	1.82e-282	769.0	COG2957@1|root,COG2957@2|Bacteria,1TQS5@1239|Firmicutes,248CP@186801|Clostridia	186801|Clostridia	E	agmatine deiminase	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
NGKEMLHH_00468	457412.RSAG_03394	2.5e-283	772.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia,3WGYP@541000|Ruminococcaceae	186801|Clostridia	E	carboxynorspermidine decarboxylase	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
NGKEMLHH_00469	1121115.AXVN01000128_gene275	8.26e-309	841.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,3XYN8@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
NGKEMLHH_00470	1121115.AXVN01000128_gene276	9.27e-217	597.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,3XZ5Q@572511|Blautia	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
NGKEMLHH_00471	1121115.AXVN01000128_gene277	0.0	948.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3XZBZ@572511|Blautia	186801|Clostridia	E	Orn Lys Arg decarboxylase, major domain protein	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
NGKEMLHH_00472	199310.c2408	2.45e-134	380.0	2E80D@1|root,332EP@2|Bacteria,1NAIR@1224|Proteobacteria,1SDWZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein involved in DNA replication and plasmid maintenance	-	-	-	-	-	-	-	-	-	-	-	-	RepL
NGKEMLHH_00474	199310.c2410	1.04e-98	288.0	2C6W8@1|root,32RHW@2|Bacteria,1RHZ7@1224|Proteobacteria,1S7U6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4756)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4756
NGKEMLHH_00475	199310.c2411	2.74e-82	244.0	COG2916@1|root,COG2916@2|Bacteria,1RF2B@1224|Proteobacteria,1S59N@1236|Gammaproteobacteria,3XRKK@561|Escherichia	1236|Gammaproteobacteria	L	H-NS histone family	-	-	-	ko:K03746	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	Histone_HNS
NGKEMLHH_00476	199310.c2413	4.4e-47	151.0	2E1FT@1|root,32WUF@2|Bacteria,1N20A@1224|Proteobacteria,1SBFZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00477	199310.c2414	3.2e-64	196.0	2F2QH@1|root,33VKT@2|Bacteria,1NWS3@1224|Proteobacteria,1SPBE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00478	199310.c2415	1.38e-67	204.0	2FIPA@1|root,34AF3@2|Bacteria,1P1QN@1224|Proteobacteria,1SRWV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00479	362663.ECP_1932	2.06e-46	149.0	COG3311@1|root,COG3311@2|Bacteria,1NGB9@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	ko:K07733	-	-	-	-	ko00000,ko03000	-	-	-	Phage_AlpA
NGKEMLHH_00480	199310.c2416	2.13e-193	538.0	2E69M@1|root,30JYF@2|Bacteria,1REWG@1224|Proteobacteria,1S5NZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00482	1232447.BAHW02000027_gene2057	5.59e-41	135.0	2D2HR@1|root,32TCU@2|Bacteria,1VA21@1239|Firmicutes,24MT0@186801|Clostridia	186801|Clostridia	S	Sporulation initiation factor Spo0A C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
NGKEMLHH_00483	1232447.BAHW02000027_gene2056	5.84e-95	277.0	2DE2W@1|root,2ZKAM@2|Bacteria,1V3EH@1239|Firmicutes,24GFD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00484	411469.EUBHAL_00472	4.19e-107	310.0	2DBT4@1|root,2ZAVD@2|Bacteria,1V0AF@1239|Firmicutes,24DH6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
NGKEMLHH_00485	457412.RSAG_03098	1.67e-79	236.0	COG2337@1|root,COG2337@2|Bacteria,1TTJP@1239|Firmicutes,25MHP@186801|Clostridia,3WQFT@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
NGKEMLHH_00487	457412.RSAG_03096	0.0	1061.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WG90@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_00488	457412.RSAG_03095	0.0	1110.0	COG1961@1|root,COG1961@2|Bacteria,1V29C@1239|Firmicutes,24GBE@186801|Clostridia	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_00490	1507.HMPREF0262_01329	7.98e-310	844.0	COG0582@1|root,COG0582@2|Bacteria,1TSQW@1239|Firmicutes,249T6@186801|Clostridia,36WP0@31979|Clostridiaceae	186801|Clostridia	L	Site-specific recombinase, phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NGKEMLHH_00491	1507.HMPREF0262_01638	2.3e-149	421.0	COG1396@1|root,COG1396@2|Bacteria,1U9CN@1239|Firmicutes,24E9S@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_00492	1235790.C805_01031	3.92e-37	125.0	2DAN3@1|root,32TVS@2|Bacteria,1VABD@1239|Firmicutes,24PA6@186801|Clostridia,25X04@186806|Eubacteriaceae	186801|Clostridia	L	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NGKEMLHH_00493	500632.CLONEX_01477	9.62e-277	764.0	28HPA@1|root,2Z7XB@2|Bacteria,1TRBX@1239|Firmicutes,24AUG@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NGKEMLHH_00494	411467.BACCAP_00841	9.94e-72	217.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia,26BMA@186813|unclassified Clostridiales	186801|Clostridia	T	Low molecular weight phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
NGKEMLHH_00495	478749.BRYFOR_06464	1.6e-23	92.0	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes	1239|Firmicutes	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
NGKEMLHH_00496	478749.BRYFOR_06465	5.64e-214	594.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia	186801|Clostridia	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
NGKEMLHH_00497	478749.BRYFOR_06466	8.67e-64	195.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,24QZK@186801|Clostridia	186801|Clostridia	K	regulatory protein, arsR	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
NGKEMLHH_00498	469596.HMPREF9488_02272	1.43e-64	199.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V5QY@1239|Firmicutes,3VUQV@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NGKEMLHH_00499	742765.HMPREF9457_02001	4.82e-155	436.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,27W2W@189330|Dorea	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_00500	411463.EUBVEN_00937	9.56e-193	537.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,25W55@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NGKEMLHH_00501	742765.HMPREF9457_02003	1.14e-158	445.0	COG0745@1|root,COG0745@2|Bacteria,1TSNV@1239|Firmicutes,2493A@186801|Clostridia,27WSY@189330|Dorea	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_00502	1256908.HMPREF0373_02451	3.34e-80	238.0	2C5R4@1|root,2ZRGD@2|Bacteria,1V4WH@1239|Firmicutes,24HA6@186801|Clostridia,25WJJ@186806|Eubacteriaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NGKEMLHH_00503	552396.HMPREF0863_01519	4.25e-55	185.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,3VNQ8@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
NGKEMLHH_00504	1256908.HMPREF0373_00982	4.92e-242	665.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,24A19@186801|Clostridia,25WRD@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
NGKEMLHH_00505	1256908.HMPREF0373_00983	8.55e-152	444.0	COG0323@1|root,COG0323@2|Bacteria,1VSSE@1239|Firmicutes,24ZJR@186801|Clostridia	186801|Clostridia	L	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
NGKEMLHH_00506	1121115.AXVN01000042_gene3035	2.7e-65	199.0	COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,24J7Q@186801|Clostridia,3Y040@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NGKEMLHH_00507	1121115.AXVN01000042_gene3036	0.0	1552.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3XYKC@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 9.98	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
NGKEMLHH_00508	1121115.AXVN01000042_gene3037	8.12e-90	263.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia,3Y05D@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00509	1121115.AXVN01000042_gene3038	0.0	887.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,3XYVQ@572511|Blautia	186801|Clostridia	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
NGKEMLHH_00510	457412.RSAG_01705	8.77e-69	212.0	COG0637@1|root,COG0637@2|Bacteria,1V1IW@1239|Firmicutes,24FZZ@186801|Clostridia,3WRQ7@541000|Ruminococcaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	CpXC,HAD_2
NGKEMLHH_00511	1121115.AXVN01000042_gene3039	1.19e-68	211.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,3Y042@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Mannitol_dh_C
NGKEMLHH_00512	1121115.AXVN01000042_gene3040	0.0	871.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3Y1DM@572511|Blautia	186801|Clostridia	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NGKEMLHH_00513	457412.RSAG_01411	1.18e-223	614.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,3WGYH@541000|Ruminococcaceae	186801|Clostridia	J	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
NGKEMLHH_00514	1121115.AXVN01000010_gene2796	1.6e-226	626.0	COG1172@1|root,COG1172@2|Bacteria,1TPPT@1239|Firmicutes,248FJ@186801|Clostridia,3Y1F9@572511|Blautia	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	yjfF	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NGKEMLHH_00515	1121115.AXVN01000010_gene2795	7.39e-233	643.0	COG1172@1|root,COG1172@2|Bacteria,1TR6F@1239|Firmicutes,2484T@186801|Clostridia,3Y10U@572511|Blautia	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	ytfT	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NGKEMLHH_00516	457412.RSAG_01414	0.0	980.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3WH2F@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system, ATPase component	araG_1	-	3.6.3.17	ko:K02056,ko:K10441	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
NGKEMLHH_00517	1121115.AXVN01000010_gene2793	4.22e-244	671.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3Y1DY@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
NGKEMLHH_00518	470145.BACCOP_01657	8.17e-86	263.0	2F19W@1|root,300NE@2|Bacteria,4PHRV@976|Bacteroidetes,2FRTN@200643|Bacteroidia,4APS7@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00519	470145.BACCOP_01654	9.2e-137	389.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,2FS9A@200643|Bacteroidia,4AQSS@815|Bacteroidaceae	976|Bacteroidetes	L	COG2003 DNA repair	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
NGKEMLHH_00520	470145.BACCOP_01650	1.76e-127	363.0	COG1961@1|root,COG1961@2|Bacteria,4NNF6@976|Bacteroidetes,2FQXB@200643|Bacteroidia,4ARM9@815|Bacteroidaceae	976|Bacteroidetes	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
NGKEMLHH_00521	470145.BACCOP_01649	1.14e-66	202.0	2A89U@1|root,30XB3@2|Bacteria,4PAQS@976|Bacteroidetes,2FXI9@200643|Bacteroidia,4ATVJ@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00522	395493.BegalDRAFT_2344	0.000367	47.4	COG1403@1|root,COG1403@2|Bacteria,1RGA2@1224|Proteobacteria,1RZU3@1236|Gammaproteobacteria,462WY@72273|Thiotrichales	72273|Thiotrichales	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00523	449447.MAE_39710	2.96e-86	276.0	COG3950@1|root,COG3950@2|Bacteria,1G2F1@1117|Cyanobacteria	1117|Cyanobacteria	S	ATP-binding protein involved in virulence	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
NGKEMLHH_00524	1236508.BAKF01000013_gene1295	1.39e-33	115.0	arCOG12966@1|root,3325K@2|Bacteria,4NXI4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00525	1161902.HMPREF0378_0105	3.49e-123	353.0	28NWJ@1|root,2ZBUE@2|Bacteria,1V240@1239|Firmicutes,25DUD@186801|Clostridia	186801|Clostridia	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
NGKEMLHH_00526	1537994.JQFW01000010_gene2842	2.25e-36	137.0	COG0846@1|root,COG0846@2|Bacteria,1MXU2@1224|Proteobacteria,1RZ1C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	NAD-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
NGKEMLHH_00528	457412.RSAG_00136	1.98e-118	339.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia,3WJYV@541000|Ruminococcaceae	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
NGKEMLHH_00529	457412.RSAG_00137	2.89e-208	577.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,3WIMD@541000|Ruminococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
NGKEMLHH_00530	1121115.AXVN01000020_gene89	1.2e-240	661.0	COG1077@1|root,COG1077@2|Bacteria,1TPVU@1239|Firmicutes,248CM@186801|Clostridia,3XZ2N@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
NGKEMLHH_00531	1121115.AXVN01000020_gene88	2.22e-171	478.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,3XZVG@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
NGKEMLHH_00532	457412.RSAG_00140	0.0	925.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,3WGFA@541000|Ruminococcaceae	186801|Clostridia	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
NGKEMLHH_00534	1121115.AXVN01000066_gene3218	6.62e-164	458.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,3XZ8R@572511|Blautia	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
NGKEMLHH_00535	1121115.AXVN01000066_gene3219	1.12e-246	677.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3XYPY@572511|Blautia	186801|Clostridia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
NGKEMLHH_00536	1121115.AXVN01000066_gene3220	1.62e-225	620.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,3XZ6W@572511|Blautia	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
NGKEMLHH_00537	457412.RSAG_01972	6.29e-100	290.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WKHF@541000|Ruminococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
NGKEMLHH_00538	457412.RSAG_01973	2.76e-162	455.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,3WJ9X@541000|Ruminococcaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
NGKEMLHH_00539	1121115.AXVN01000066_gene3223	1.05e-102	296.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3Y003@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
NGKEMLHH_00540	1121115.AXVN01000066_gene3224	9.9e-126	357.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
NGKEMLHH_00541	457412.RSAG_01976	8.73e-154	432.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,3WIHN@541000|Ruminococcaceae	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
NGKEMLHH_00542	457412.RSAG_01977	0.0	1590.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia,3WSNS@541000|Ruminococcaceae	186801|Clostridia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
NGKEMLHH_00543	457412.RSAG_01978	1.18e-224	619.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHF9@541000|Ruminococcaceae	186801|Clostridia	GK	Psort location Cytoplasmic, score	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
NGKEMLHH_00544	1121115.AXVN01000066_gene3228	4.97e-220	607.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,3XZ5K@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
NGKEMLHH_00545	1121115.AXVN01000066_gene3229	0.0	1214.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,3XZ8C@572511|Blautia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
NGKEMLHH_00546	457412.RSAG_01981	0.0	1248.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3WG9V@541000|Ruminococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NGKEMLHH_00547	1121115.AXVN01000066_gene3231	0.0	973.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia,3XYIV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
NGKEMLHH_00548	1121115.AXVN01000066_gene3232	3.68e-179	498.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3XZZF@572511|Blautia	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
NGKEMLHH_00549	457412.RSAG_01984	4.9e-199	550.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,3WJDK@541000|Ruminococcaceae	186801|Clostridia	S	Carbon-nitrogen hydrolase	nit	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
NGKEMLHH_00550	1121115.AXVN01000001_gene1050	3.98e-29	104.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,3Y0K6@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
NGKEMLHH_00551	1121115.AXVN01000001_gene1051	0.0	1625.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3XYZ6@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NGKEMLHH_00552	1121115.AXVN01000001_gene1052	9.11e-302	822.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3XYHR@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
NGKEMLHH_00553	457412.RSAG_01073	3.35e-203	577.0	COG5263@1|root,COG5263@2|Bacteria,1TPVT@1239|Firmicutes,24DEH@186801|Clostridia,3WQ86@541000|Ruminococcaceae	186801|Clostridia	M	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,LRR_5,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N
NGKEMLHH_00554	1121115.AXVN01000001_gene1054	1.1e-29	109.0	2F3CT@1|root,33W6S@2|Bacteria,1VVCN@1239|Firmicutes,250TA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00555	457412.RSAG_01076	6.36e-34	116.0	2FGS5@1|root,348MK@2|Bacteria,1W0U5@1239|Firmicutes,2540A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00558	1195236.CTER_2095	2.86e-19	99.4	COG1653@1|root,COG1653@2|Bacteria,1UP3E@1239|Firmicutes,25H5X@186801|Clostridia,3WS3X@541000|Ruminococcaceae	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_00559	272562.CA_C0665	6.06e-77	243.0	COG1175@1|root,COG1175@2|Bacteria,1TQTC@1239|Firmicutes,24AQX@186801|Clostridia,36GI8@31979|Clostridiaceae	186801|Clostridia	G	ABC transporter, permease protein	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_00560	1195236.CTER_4358	4.08e-90	276.0	COG0395@1|root,COG0395@2|Bacteria,1TS82@1239|Firmicutes,2488S@186801|Clostridia,3WHSW@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_00562	580327.Tthe_0471	4.32e-06	57.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,42FNY@68295|Thermoanaerobacterales	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NGKEMLHH_00564	196367.JNFG01000206_gene185	6.74e-23	108.0	2C9CN@1|root,2ZFFI@2|Bacteria,1R9X1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00566	457412.RSAG_00966	5.24e-296	808.0	2DEDR@1|root,2ZMJC@2|Bacteria,1V31W@1239|Firmicutes,24FHB@186801|Clostridia,3WPN4@541000|Ruminococcaceae	186801|Clostridia	S	Bacteriophage abortive infection AbiH	-	-	-	-	-	-	-	-	-	-	-	-	AbiH
NGKEMLHH_00567	457412.RSAG_00965	0.0	1373.0	COG3972@1|root,COG3972@2|Bacteria,1U80C@1239|Firmicutes,24EBG@186801|Clostridia,3WKQH@541000|Ruminococcaceae	186801|Clostridia	S	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
NGKEMLHH_00568	457412.RSAG_00964	1.84e-159	446.0	COG5619@1|root,COG5619@2|Bacteria,1VATP@1239|Firmicutes,24Q9K@186801|Clostridia,3WPND@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized conserved protein (DUF2290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2290
NGKEMLHH_00569	1121115.AXVN01000003_gene1618	2.26e-149	419.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24J27@186801|Clostridia,3Y2AD@572511|Blautia	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NGKEMLHH_00570	457412.RSAG_00637	0.0	1566.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3WHBB@541000|Ruminococcaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
NGKEMLHH_00571	457412.RSAG_00638	5.78e-225	622.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WGWV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
NGKEMLHH_00572	1121115.AXVN01000003_gene1622	1.92e-143	415.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3XZ00@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
NGKEMLHH_00573	1121115.AXVN01000025_gene955	4.69e-86	253.0	COG2087@1|root,COG2087@2|Bacteria,1VG8S@1239|Firmicutes,24QSM@186801|Clostridia,3Y0HX@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	CobU
NGKEMLHH_00574	1121115.AXVN01000025_gene954	4.31e-183	509.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,3Y00I@572511|Blautia	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
NGKEMLHH_00575	1121115.AXVN01000025_gene953	3.68e-125	356.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,3Y004@572511|Blautia	186801|Clostridia	H	COG COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
NGKEMLHH_00576	1121115.AXVN01000025_gene952	1.08e-245	675.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,3XYHW@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
NGKEMLHH_00577	1121115.AXVN01000025_gene951	1.77e-89	263.0	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,257NM@186801|Clostridia,3Y0BG@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
NGKEMLHH_00578	1121115.AXVN01000025_gene950	2.84e-218	603.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,3XYSZ@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
NGKEMLHH_00579	1121115.AXVN01000025_gene949	0.0	1280.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24A98@186801|Clostridia,3Y056@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
NGKEMLHH_00580	1121115.AXVN01000002_gene1345	0.0	875.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XYXE@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
NGKEMLHH_00581	457412.RSAG_00942	7.41e-229	630.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,3WGC0@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
NGKEMLHH_00582	1121115.AXVN01000002_gene1347	4.29e-128	365.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia,3XZTQ@572511|Blautia	186801|Clostridia	P	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
NGKEMLHH_00583	1121115.AXVN01000002_gene1348	2.48e-162	455.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,3XYKR@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
NGKEMLHH_00584	1121115.AXVN01000002_gene1349	9.51e-122	348.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,3XYQD@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
NGKEMLHH_00585	1121115.AXVN01000002_gene1350	5.72e-195	540.0	COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,3XZFG@572511|Blautia	186801|Clostridia	C	F420-non-reducing hydrogenase	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
NGKEMLHH_00586	457412.RSAG_00937	9.43e-132	375.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,3WIM6@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
NGKEMLHH_00587	1121115.AXVN01000002_gene1352	3.72e-238	655.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,3XZK8@572511|Blautia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
NGKEMLHH_00588	457412.RSAG_02096	3.47e-224	620.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia,3WHSG@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
NGKEMLHH_00589	1121115.AXVN01000063_gene713	5.53e-265	726.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XYK4@572511|Blautia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
NGKEMLHH_00590	1121115.AXVN01000063_gene712	1.44e-256	704.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,25N06@186801|Clostridia,3XYXQ@572511|Blautia	186801|Clostridia	KT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NGKEMLHH_00591	457412.RSAG_04588	7.5e-263	719.0	COG3842@1|root,COG3842@2|Bacteria,1TQ18@1239|Firmicutes,24AEK@186801|Clostridia,3WGIR@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
NGKEMLHH_00592	457412.RSAG_04589	3e-156	439.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,3WIYG@541000|Ruminococcaceae	186801|Clostridia	P	Molybdate ABC transporter	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
NGKEMLHH_00593	1121115.AXVN01000063_gene709	5.22e-184	515.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,3Y07V@572511|Blautia	186801|Clostridia	P	COG COG0725 ABC-type molybdate transport system, periplasmic component	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
NGKEMLHH_00594	457412.RSAG_01908	5.56e-123	361.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3WIB4@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
NGKEMLHH_00596	457412.RSAG_00488	2.79e-191	532.0	2FCDN@1|root,344H7@2|Bacteria,1W31R@1239|Firmicutes,256SW@186801|Clostridia	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00597	457412.RSAG_00487	3.39e-121	346.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WJQH@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NGKEMLHH_00598	457412.RSAG_00486	8.04e-257	705.0	2ACB9@1|root,311W7@2|Bacteria,1V49X@1239|Firmicutes,24NF4@186801|Clostridia,3WJZP@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NGKEMLHH_00599	457412.RSAG_00485	6.23e-77	229.0	COG1554@1|root,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,248K8@186801|Clostridia	186801|Clostridia	G	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,F5_F8_type_C,Glyco_hyd_65N_2
NGKEMLHH_00600	457412.RSAG_00484	7.22e-119	340.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,3WJXC@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NGKEMLHH_00601	457412.RSAG_00483	0.0	932.0	28NHG@1|root,2ZBJ9@2|Bacteria,1V1QG@1239|Firmicutes,24GQ1@186801|Clostridia,3WM85@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NGKEMLHH_00602	457412.RSAG_00896	0.0	1791.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TVCK@1239|Firmicutes,25KKE@186801|Clostridia,3WNVM@541000|Ruminococcaceae	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
NGKEMLHH_00603	457412.RSAG_00895	0.0	1820.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
NGKEMLHH_00604	457412.RSAG_00894	8.94e-100	289.0	COG2198@1|root,COG3437@1|root,COG2198@2|Bacteria,COG3437@2|Bacteria,1VG8R@1239|Firmicutes,24QS0@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
NGKEMLHH_00605	1121115.AXVN01000020_gene127	3.52e-62	190.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,3Y06C@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
NGKEMLHH_00606	1121115.AXVN01000020_gene128	1.58e-70	212.0	COG2868@1|root,COG2868@2|Bacteria,1VCNG@1239|Firmicutes,25N63@186801|Clostridia,3Y0KN@572511|Blautia	186801|Clostridia	J	Cysteine protease Prp	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
NGKEMLHH_00607	1121115.AXVN01000020_gene129	3.99e-64	196.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,3Y060@572511|Blautia	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
NGKEMLHH_00608	457412.RSAG_00096	3.6e-285	780.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia,3WICU@541000|Ruminococcaceae	186801|Clostridia	J	TIGRFAM ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
NGKEMLHH_00609	457412.RSAG_00095	9.74e-164	458.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,3WJDP@541000|Ruminococcaceae	186801|Clostridia	S	Radical SAM-linked protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
NGKEMLHH_00610	457412.RSAG_00094	0.0	1254.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,3WHME@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NGKEMLHH_00611	1121115.AXVN01000023_gene1788	7.42e-162	453.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,3XZ1X@572511|Blautia	186801|Clostridia	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
NGKEMLHH_00612	1121115.AXVN01000023_gene1789	5.84e-86	253.0	2E5KN@1|root,330BS@2|Bacteria,1V5P2@1239|Firmicutes,24TCR@186801|Clostridia,3Y0HH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00613	457412.RSAG_02657	1.45e-280	766.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia,3WSRX@541000|Ruminococcaceae	186801|Clostridia	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
NGKEMLHH_00614	457412.RSAG_02656	0.0	1588.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia,3WI6Z@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
NGKEMLHH_00615	1121115.AXVN01000023_gene1792	0.0	997.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3XZID@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
NGKEMLHH_00616	457412.RSAG_02654	0.0	1508.0	COG2247@1|root,COG2755@1|root,COG2247@2|Bacteria,COG2755@2|Bacteria,1UKIA@1239|Firmicutes,25FXT@186801|Clostridia,3WMKI@541000|Ruminococcaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00617	1121115.AXVN01000023_gene1794	0.0	940.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,3XZAQ@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
NGKEMLHH_00618	1121115.AXVN01000023_gene1795	1.06e-261	716.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,3XZ47@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
NGKEMLHH_00619	457412.RSAG_02651	1.39e-297	815.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,24E0A@186801|Clostridia,3WKD3@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
NGKEMLHH_00620	457412.RSAG_02650	2.46e-292	797.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ribose-phosphate pyrophosphokinase family	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
NGKEMLHH_00621	457412.RSAG_02649	5.45e-232	639.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,3WJBS@541000|Ruminococcaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
NGKEMLHH_00622	457412.RSAG_02648	7.47e-269	737.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,3WJJV@541000|Ruminococcaceae	186801|Clostridia	L	DnaD domain protein	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
NGKEMLHH_00623	199310.c2396	1.66e-59	184.0	2E1N7@1|root,3342Y@2|Bacteria,1N9QT@1224|Proteobacteria,1SD7F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Conjugal transfer protein TraD	-	-	-	-	-	-	-	-	-	-	-	-	TraD
NGKEMLHH_00624	199310.c2395	4.69e-110	318.0	COG2165@1|root,COG2165@2|Bacteria,1QWXN@1224|Proteobacteria,1T2YR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	PilS N terminal	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,PilS
NGKEMLHH_00625	199310.c2394	0.0	890.0	COG2165@1|root,COG2165@2|Bacteria,1R8RT@1224|Proteobacteria,1RNX8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Bacterial shufflon protein, N-terminal constant region	-	-	-	-	-	-	-	-	-	-	-	-	Shufflon_N
NGKEMLHH_00626	199310.c2393	0.0	1193.0	2BTV5@1|root,32P2X@2|Bacteria,1N16J@1224|Proteobacteria,1SMSA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00627	199310.c2392	4.47e-296	807.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
NGKEMLHH_00628	1121115.AXVN01000029_gene648	1.31e-285	783.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3XZS0@572511|Blautia	186801|Clostridia	S	COG COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
NGKEMLHH_00629	457412.RSAG_00527	5.99e-143	403.0	COG1434@1|root,COG1434@2|Bacteria,1V32X@1239|Firmicutes,24ATY@186801|Clostridia,3WITP@541000|Ruminococcaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
NGKEMLHH_00630	1121115.AXVN01000029_gene650	4.72e-150	425.0	COG0860@1|root,COG0860@2|Bacteria,1TS91@1239|Firmicutes,25B1N@186801|Clostridia,3XZHM@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	cwlC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SPOR
NGKEMLHH_00631	411459.RUMOBE_02892	0.0	1065.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYKU@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_00632	445973.CLOBAR_01087	8.91e-63	197.0	2CAJN@1|root,33W13@2|Bacteria,1VW8W@1239|Firmicutes,250Y9@186801|Clostridia,25U56@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00633	1121333.JMLH01000019_gene1519	2.5e-49	157.0	2BVCS@1|root,32QSU@2|Bacteria,1UHK3@1239|Firmicutes	1239|Firmicutes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NGKEMLHH_00634	1121333.JMLH01000019_gene1518	1.51e-95	278.0	COG1595@1|root,COG1595@2|Bacteria,1V1UU@1239|Firmicutes,3VUPD@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
NGKEMLHH_00635	457412.RSAG_03495	1.47e-315	860.0	COG3594@1|root,COG3594@2|Bacteria	2|Bacteria	G	nodulation	-	-	-	ko:K13663	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
NGKEMLHH_00636	457412.RSAG_01661	0.0	863.0	COG0615@1|root,COG0673@1|root,COG0615@2|Bacteria,COG0673@2|Bacteria,1V3KY@1239|Firmicutes,24BKY@186801|Clostridia,3WIHC@541000|Ruminococcaceae	186801|Clostridia	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,GFO_IDH_MocA
NGKEMLHH_00637	457412.RSAG_01660	0.0	1555.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,3WKER@541000|Ruminococcaceae	186801|Clostridia	M	LicD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
NGKEMLHH_00638	457412.RSAG_01659	9.33e-256	704.0	COG3475@1|root,COG3475@2|Bacteria	2|Bacteria	M	LICD family	licD	-	-	ko:K02011,ko:K07271,ko:K19872	ko00515,ko01100,ko02010,map00515,map01100,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko04131	3.A.1.10	-	-	LicD
NGKEMLHH_00639	1121115.AXVN01000108_gene624	1.26e-285	780.0	COG1653@1|root,COG1653@2|Bacteria,1UUUK@1239|Firmicutes,25MFP@186801|Clostridia,3Y1WB@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
NGKEMLHH_00640	1121115.AXVN01000108_gene625	5.48e-204	565.0	COG1175@1|root,COG1175@2|Bacteria,1UXJE@1239|Firmicutes,25MIM@186801|Clostridia,3Y1QD@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_00641	457412.RSAG_01553	6.61e-193	536.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249S6@186801|Clostridia,3WP49@541000|Ruminococcaceae	186801|Clostridia	P	COG COG0395 ABC-type sugar transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_00642	1121115.AXVN01000108_gene627	0.0	984.0	COG1621@1|root,COG1621@2|Bacteria,1U0EK@1239|Firmicutes,24AM9@186801|Clostridia,3Y1NF@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF4975)	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	DUF4975,Glyco_hydro_32N
NGKEMLHH_00643	457412.RSAG_01551	1.12e-269	741.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,3WISY@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
NGKEMLHH_00644	500632.CLONEX_02466	6.87e-161	451.0	COG0745@1|root,COG0745@2|Bacteria,1UZIS@1239|Firmicutes,24CCE@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_00645	552398.HMPREF0866_02682	9.14e-300	819.0	COG5002@1|root,COG5002@2|Bacteria,1URKI@1239|Firmicutes,248WK@186801|Clostridia,3WIIQ@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NGKEMLHH_00646	552398.HMPREF0866_02685	1.35e-88	260.0	COG1595@1|root,COG1595@2|Bacteria,1V1EX@1239|Firmicutes,25DT3@186801|Clostridia,3WS45@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
NGKEMLHH_00647	411473.RUMCAL_02940	1.1e-139	397.0	COG1277@1|root,2Z99C@2|Bacteria,1TQMN@1239|Firmicutes,25D6E@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
NGKEMLHH_00648	411473.RUMCAL_02939	1.25e-209	580.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,3WHBQ@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_00649	411473.RUMCAL_02938	3.8e-201	559.0	COG0642@1|root,COG2205@2|Bacteria,1TPK5@1239|Firmicutes,247J0@186801|Clostridia,3WK2Q@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NGKEMLHH_00650	411473.RUMCAL_02937	4.12e-158	444.0	COG0745@1|root,COG0745@2|Bacteria,1TRK5@1239|Firmicutes,25B21@186801|Clostridia,3WRPE@541000|Ruminococcaceae	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_00651	411473.RUMCAL_02936	3.54e-43	140.0	COG2909@1|root,COG2909@2|Bacteria,1VGAF@1239|Firmicutes,24SMP@186801|Clostridia,3WM0N@541000|Ruminococcaceae	186801|Clostridia	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NGKEMLHH_00652	1121115.AXVN01000047_gene1270	1.1e-48	155.0	2EVPB@1|root,33P3A@2|Bacteria,1VN4M@1239|Firmicutes,24TZY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00653	1121115.AXVN01000177_gene3485	2.1e-269	738.0	COG3584@1|root,COG3584@2|Bacteria,1UVF9@1239|Firmicutes,25AFQ@186801|Clostridia,3XZV0@572511|Blautia	186801|Clostridia	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
NGKEMLHH_00654	457412.RSAG_01848	1.95e-316	861.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WH4H@541000|Ruminococcaceae	186801|Clostridia	E	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NGKEMLHH_00656	1121115.AXVN01000052_gene867	6.8e-294	801.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,3XZHU@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
NGKEMLHH_00657	1121115.AXVN01000089_gene2815	0.0	1420.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3Y1FS@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
NGKEMLHH_00658	1121115.AXVN01000089_gene2814	9.11e-196	542.0	COG0834@1|root,COG0834@2|Bacteria,1UYKY@1239|Firmicutes,24C0B@186801|Clostridia,3Y14K@572511|Blautia	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NGKEMLHH_00659	1121115.AXVN01000089_gene2813	3.24e-308	842.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYX6@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_00660	1121115.AXVN01000089_gene2812	1.64e-103	299.0	COG1522@1|root,COG1522@2|Bacteria,1V1DR@1239|Firmicutes,25DYB@186801|Clostridia,3Y283@572511|Blautia	186801|Clostridia	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
NGKEMLHH_00661	1121115.AXVN01000126_gene3818	8.48e-176	496.0	COG3266@1|root,COG3266@2|Bacteria,1VS06@1239|Firmicutes,24YEU@186801|Clostridia,3Y1K6@572511|Blautia	186801|Clostridia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00662	457412.RSAG_01783	0.0	1489.0	COG4733@1|root,COG4870@1|root,COG4733@2|Bacteria,COG4870@2|Bacteria,1V2GU@1239|Firmicutes,24GPX@186801|Clostridia,3WRJP@541000|Ruminococcaceae	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Flg_new,Peptidase_C1
NGKEMLHH_00663	1121115.AXVN01000126_gene3816	5.48e-74	220.0	COG2158@1|root,COG2158@2|Bacteria,1VFNA@1239|Firmicutes,24MYB@186801|Clostridia,3Y0C2@572511|Blautia	186801|Clostridia	S	Cysteine-rich small domain	-	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
NGKEMLHH_00664	457412.RSAG_01785	4.45e-120	343.0	COG4917@1|root,COG4917@2|Bacteria,1V54Y@1239|Firmicutes,25DMI@186801|Clostridia	186801|Clostridia	E	Ethanolamine utilisation - propanediol utilisation	-	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
NGKEMLHH_00665	1121115.AXVN01000126_gene3814	9.74e-98	284.0	COG4810@1|root,COG4810@2|Bacteria,1V5A1@1239|Firmicutes,24IPC@186801|Clostridia,3Y03M@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
NGKEMLHH_00666	1121115.AXVN01000126_gene3813	1.73e-81	241.0	COG4810@1|root,COG4810@2|Bacteria,1V452@1239|Firmicutes,25DMT@186801|Clostridia,3Y27X@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
NGKEMLHH_00667	1121115.AXVN01000035_gene3836	2.28e-58	180.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,3Y0G3@572511|Blautia	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
NGKEMLHH_00668	457412.RSAG_02944	9.05e-93	271.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,3WJ8E@541000|Ruminococcaceae	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
NGKEMLHH_00669	1121115.AXVN01000035_gene3834	4.26e-45	146.0	2E3Y4@1|root,32YV4@2|Bacteria,1VFRH@1239|Firmicutes,24QXW@186801|Clostridia,3Y0M4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
NGKEMLHH_00670	457412.RSAG_02946	0.0	1226.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3WH9M@541000|Ruminococcaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
NGKEMLHH_00671	1121115.AXVN01000035_gene3832	6.22e-74	221.0	COG3679@1|root,COG3679@2|Bacteria,1VH19@1239|Firmicutes,24RNC@186801|Clostridia,3Y0MG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
NGKEMLHH_00672	1121115.AXVN01000035_gene3831	7.59e-89	261.0	COG1559@1|root,COG1559@2|Bacteria,1VGA6@1239|Firmicutes,24RBR@186801|Clostridia,3Y0GT@572511|Blautia	186801|Clostridia	S	YceG-like family	-	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
NGKEMLHH_00673	457412.RSAG_02949	2.06e-150	423.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,3WI82@541000|Ruminococcaceae	186801|Clostridia	S	O-methyltransferase	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
NGKEMLHH_00674	1121115.AXVN01000035_gene3829	4.02e-304	828.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,3XYM5@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
NGKEMLHH_00675	457412.RSAG_02951	5.91e-143	404.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia,3WG7B@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
NGKEMLHH_00676	411460.RUMTOR_02554	1.69e-127	374.0	2CC51@1|root,2Z7IU@2|Bacteria,1TQNI@1239|Firmicutes,24DDD@186801|Clostridia,3XZP6@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397
NGKEMLHH_00677	411460.RUMTOR_02552	5.86e-53	185.0	COG1196@1|root,COG1196@2|Bacteria,1TPW9@1239|Firmicutes,247V7@186801|Clostridia,3Y11R@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
NGKEMLHH_00678	411460.RUMTOR_02551	1.28e-302	825.0	COG4924@1|root,COG4924@2|Bacteria,1TRVG@1239|Firmicutes,24D0P@186801|Clostridia,3Y175@572511|Blautia	186801|Clostridia	S	COG NOG10831 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
NGKEMLHH_00679	665950.HMPREF1025_02187	4.98e-293	799.0	COG2169@1|root,COG2207@1|root,COG2169@2|Bacteria,COG2207@2|Bacteria,1TRWX@1239|Firmicutes,24BKU@186801|Clostridia,27TB0@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_18
NGKEMLHH_00680	665950.HMPREF1025_02186	0.0	1269.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,27I89@186928|unclassified Lachnospiraceae	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,Oxidored_FMN,Pyr_redox_2
NGKEMLHH_00682	457412.RSAG_02248	9.29e-151	429.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WJDM@541000|Ruminococcaceae	186801|Clostridia	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034,ko:K13891	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	BPD_transp_1,OppC_N
NGKEMLHH_00683	457412.RSAG_02249	2.42e-236	650.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WGTC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NGKEMLHH_00684	457412.RSAG_04635	4.02e-237	651.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WH83@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NGKEMLHH_00685	457412.RSAG_02250	4.18e-171	479.0	COG1349@1|root,COG1349@2|Bacteria,1TSU1@1239|Firmicutes,25C4E@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, DeoR	-	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NGKEMLHH_00686	457412.RSAG_02251	1.24e-177	494.0	COG3142@1|root,COG3142@2|Bacteria,1UYI8@1239|Firmicutes,247QB@186801|Clostridia,3WIQQ@541000|Ruminococcaceae	186801|Clostridia	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
NGKEMLHH_00687	1121115.AXVN01000028_gene215	0.0	1647.0	COG1305@1|root,COG1305@2|Bacteria,1TQGN@1239|Firmicutes,249YH@186801|Clostridia,3Y18M@572511|Blautia	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NGKEMLHH_00688	1121115.AXVN01000028_gene216	0.0	942.0	COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,24B8Y@186801|Clostridia,3XYWJ@572511|Blautia	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
NGKEMLHH_00689	457412.RSAG_02254	3.58e-119	340.0	COG0614@1|root,COG0614@2|Bacteria,1UK9K@1239|Firmicutes,25FRK@186801|Clostridia,3WJHV@541000|Ruminococcaceae	186801|Clostridia	HP	small periplasmic lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00690	457412.RSAG_02255	7.15e-164	458.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,249DM@186801|Clostridia,3WIU3@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-2 C20-methyltransferase	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NGKEMLHH_00691	457412.RSAG_02256	1.5e-194	540.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,3WJGT@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	nodI	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
NGKEMLHH_00692	457412.RSAG_02257	4.48e-173	483.0	COG0842@1|root,COG0842@2|Bacteria,1UYEB@1239|Firmicutes,24BUQ@186801|Clostridia,3WMU4@541000|Ruminococcaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
NGKEMLHH_00693	1121115.AXVN01000028_gene221	0.0	1779.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Peptidase_S51,Response_reg
NGKEMLHH_00694	457412.RSAG_02260	4.91e-209	578.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,3WRR9@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NGKEMLHH_00695	457412.RSAG_02261	1.11e-284	777.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,3WH06@541000|Ruminococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
NGKEMLHH_00696	665950.HMPREF1025_02173	4.53e-107	310.0	COG1846@1|root,COG1846@2|Bacteria,1VRG4@1239|Firmicutes,25E45@186801|Clostridia,27UI6@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Replication initiator protein A (RepA) N-terminus	repA	-	-	-	-	-	-	-	-	-	-	-	RepA_N
NGKEMLHH_00697	665950.HMPREF1025_02172	8.13e-199	550.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,27JJC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
NGKEMLHH_00698	665950.HMPREF1025_02171	9.31e-44	142.0	2CCB2@1|root,32W5T@2|Bacteria,1VDNT@1239|Firmicutes,24QFS@186801|Clostridia,27PX0@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NGKEMLHH_00699	665950.HMPREF1025_02170	1.56e-297	810.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,27IJX@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
NGKEMLHH_00700	665950.HMPREF1025_02169	1.15e-113	325.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,27NAT@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Low molecular weight phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
NGKEMLHH_00701	411460.RUMTOR_01001	7.4e-164	459.0	COG0484@1|root,COG0484@2|Bacteria,1UHC4@1239|Firmicutes,25Q2I@186801|Clostridia,3Y1K9@572511|Blautia	186801|Clostridia	O	COG COG2214 DnaJ-class molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
NGKEMLHH_00702	665950.HMPREF1025_02167	1.69e-296	811.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,27K9C@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Penicillin-binding protein 5, C-terminal domain	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NGKEMLHH_00705	457412.RSAG_03071	5.46e-187	519.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,3WJ9H@541000|Ruminococcaceae	186801|Clostridia	S	dinuclear metal center protein, YbgI	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
NGKEMLHH_00706	1121115.AXVN01000005_gene2207	1.75e-166	465.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,3XZUP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
NGKEMLHH_00707	1121115.AXVN01000005_gene2206	2.44e-234	649.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3XZ4I@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
NGKEMLHH_00708	1121115.AXVN01000005_gene2205	0.0	1175.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3XYMV@572511|Blautia	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
NGKEMLHH_00709	1121115.AXVN01000005_gene2204	8.4e-53	174.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,3XYN7@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
NGKEMLHH_00710	1121115.AXVN01000012_gene3108	1.25e-203	564.0	COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,249MU@186801|Clostridia,3Y17N@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17236	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
NGKEMLHH_00711	1121115.AXVN01000012_gene3109	1.54e-222	614.0	COG1175@1|root,COG1175@2|Bacteria,1TRSP@1239|Firmicutes,24906@186801|Clostridia,3Y17F@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17235	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
NGKEMLHH_00712	1121115.AXVN01000012_gene3110	0.0	937.0	COG1653@1|root,COG1653@2|Bacteria,1TS9Z@1239|Firmicutes,2490T@186801|Clostridia,3Y14C@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17234	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_00713	1121115.AXVN01000012_gene3111	9.72e-225	619.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,3Y1E9@572511|Blautia	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
NGKEMLHH_00714	1121115.AXVN01000012_gene3112	0.0	1071.0	COG3507@1|root,COG3507@2|Bacteria,1TPHA@1239|Firmicutes,24AKT@186801|Clostridia	186801|Clostridia	G	family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Dockerin_1,GH43_C,Glyco_hydro_43,Laminin_G_3
NGKEMLHH_00715	457412.RSAG_02942	0.0	865.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,3WG80@541000|Ruminococcaceae	186801|Clostridia	J	tRNA methylthiotransferase YqeV	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
NGKEMLHH_00716	457412.RSAG_02941	1.61e-48	154.0	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,3WKEN@541000|Ruminococcaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NGKEMLHH_00717	457412.RSAG_02940	4.37e-285	778.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,3WGMK@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
NGKEMLHH_00718	1121115.AXVN01000035_gene3840	5.01e-275	752.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XYUM@572511|Blautia	186801|Clostridia	E	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NGKEMLHH_00719	457412.RSAG_02938	7.37e-170	475.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3WIFN@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
NGKEMLHH_00720	1121115.AXVN01000035_gene3842	3.51e-223	615.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,3XZAN@572511|Blautia	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
NGKEMLHH_00721	457412.RSAG_01300	1.07e-150	423.0	COG2964@1|root,COG2964@2|Bacteria,1TSI2@1239|Firmicutes,249X6@186801|Clostridia,3WM7H@541000|Ruminococcaceae	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
NGKEMLHH_00722	457412.RSAG_01301	8.44e-300	818.0	COG3290@1|root,COG3290@2|Bacteria,1TS6E@1239|Firmicutes,24DDI@186801|Clostridia,3WS78@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NGKEMLHH_00723	457412.RSAG_01302	5.89e-171	477.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,3WJ2Q@541000|Ruminococcaceae	186801|Clostridia	T	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NGKEMLHH_00724	1121115.AXVN01000001_gene1176	5.14e-42	137.0	2FI33@1|root,349VV@2|Bacteria,1VYV4@1239|Firmicutes,253ZQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00725	457412.RSAG_01304	1.1e-119	342.0	2C2RJ@1|root,33VFU@2|Bacteria,1VV8Z@1239|Firmicutes,250DV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00726	1121115.AXVN01000170_gene502	9.63e-248	679.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3XYWE@572511|Blautia	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
NGKEMLHH_00727	1121115.AXVN01000170_gene503	5.14e-111	319.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,3Y022@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
NGKEMLHH_00728	199310.c2406	1.5e-230	634.0	29ZZ4@1|root,30N0W@2|Bacteria,1RDX4@1224|Proteobacteria,1S3YU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00729	199310.c2405	1.39e-278	762.0	COG1555@1|root,COG1555@2|Bacteria,1R8YB@1224|Proteobacteria,1SHV9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
NGKEMLHH_00730	362663.ECP_1920	5.44e-109	313.0	2EPFG@1|root,33H24@2|Bacteria,1NQEH@1224|Proteobacteria,1SK7G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4755)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4755
NGKEMLHH_00731	199310.c2401	3.38e-127	362.0	28JW2@1|root,2Z9KX@2|Bacteria,1PTKR@1224|Proteobacteria,1RXXI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00732	362663.ECP_1918	8.53e-59	181.0	2BFI5@1|root,329BY@2|Bacteria,1RHEB@1224|Proteobacteria,1S5UQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00733	199310.c2400	1.57e-195	542.0	2CFYD@1|root,2Z81N@2|Bacteria,1PD7I@1224|Proteobacteria,1S0JT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00734	457412.RSAG_02586	5.98e-211	583.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3WI8A@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NGKEMLHH_00735	457412.RSAG_02585	0.0	1659.0	COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,24B8I@186801|Clostridia,3WI73@541000|Ruminococcaceae	186801|Clostridia	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
NGKEMLHH_00736	457412.RSAG_02584	0.0	1073.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
NGKEMLHH_00737	457412.RSAG_00781	2.09e-214	592.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3WGWD@541000|Ruminococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
NGKEMLHH_00738	457412.RSAG_00780	5.81e-166	465.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WGIW@541000|Ruminococcaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NGKEMLHH_00739	457412.RSAG_00779	1.14e-296	809.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WGGB@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
NGKEMLHH_00740	1121115.AXVN01000006_gene2158	3.29e-99	288.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3Y0FB@572511|Blautia	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iHN637.CLJU_RS20755	Biotin_lipoyl
NGKEMLHH_00741	1121115.AXVN01000006_gene2157	1.23e-96	281.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,3Y04Q@572511|Blautia	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
NGKEMLHH_00742	1121115.AXVN01000006_gene2156	0.0	888.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,3XZMB@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
NGKEMLHH_00743	1121115.AXVN01000019_gene164	1.59e-37	137.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,3XYPF@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
NGKEMLHH_00744	1121115.AXVN01000019_gene165	0.0	925.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3XZ83@572511|Blautia	186801|Clostridia	C	Pyruvate carboxylase, C-terminal domain subunit	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
NGKEMLHH_00745	1121115.AXVN01000019_gene166	3.46e-265	727.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,3XZ7I@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
NGKEMLHH_00746	1121115.AXVN01000019_gene167	4.25e-53	169.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
NGKEMLHH_00747	457412.RSAG_01037	1.94e-127	367.0	2DMIV@1|root,32RW6@2|Bacteria,1VAMW@1239|Firmicutes,24DVC@186801|Clostridia,3WJXG@541000|Ruminococcaceae	186801|Clostridia	C	Oxaloacetate decarboxylase, gamma chain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887,OAD_gamma
NGKEMLHH_00748	457412.RSAG_01038	0.0	920.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae	186801|Clostridia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
NGKEMLHH_00749	1121115.AXVN01000038_gene3322	3.89e-265	726.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia,3XZW7@572511|Blautia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
NGKEMLHH_00750	457412.RSAG_02285	2.29e-252	691.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,3WI2M@541000|Ruminococcaceae	186801|Clostridia	C	COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
NGKEMLHH_00751	457412.RSAG_02286	0.0	904.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3WHVA@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	gph	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2
NGKEMLHH_00752	457412.RSAG_02287	1.04e-289	793.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia,3WH7U@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_00753	1121115.AXVN01000016_gene3680	7.31e-308	841.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3XYZ0@572511|Blautia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NGKEMLHH_00754	457412.RSAG_02371	0.0	1441.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3WGTG@541000|Ruminococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
NGKEMLHH_00755	1121115.AXVN01000016_gene3678	1.18e-108	313.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,3Y03J@572511|Blautia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
NGKEMLHH_00756	457412.RSAG_02373	3.27e-227	625.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3WGPQ@541000|Ruminococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
NGKEMLHH_00757	457412.RSAG_02374	7.59e-150	423.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,3WICN@541000|Ruminococcaceae	186801|Clostridia	S	zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
NGKEMLHH_00758	457412.RSAG_02375	0.0	899.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,3WGKM@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
NGKEMLHH_00759	1121115.AXVN01000016_gene3674	2.2e-252	692.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3XZJW@572511|Blautia	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
NGKEMLHH_00760	457412.RSAG_02377	2.3e-173	484.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,3WJ4X@541000|Ruminococcaceae	186801|Clostridia	T	serine threonine protein phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
NGKEMLHH_00761	1121115.AXVN01000016_gene3672	0.0	1297.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3XZC8@572511|Blautia	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
NGKEMLHH_00762	1121115.AXVN01000016_gene3671	1.07e-209	579.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,3XZER@572511|Blautia	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
NGKEMLHH_00763	457412.RSAG_02380	8.05e-157	440.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3WISD@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
NGKEMLHH_00764	1121115.AXVN01000016_gene3669	1.96e-167	468.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3Y05M@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
NGKEMLHH_00765	1121115.AXVN01000016_gene3668	1.72e-99	289.0	COG1959@1|root,COG1959@2|Bacteria,1W6XJ@1239|Firmicutes,24SDU@186801|Clostridia,3Y0UG@572511|Blautia	186801|Clostridia	K	Winged helix-turn-helix transcription repressor, HrcA DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NGKEMLHH_00766	1121115.AXVN01000016_gene3667	3.86e-143	404.0	2ES5J@1|root,33JQC@2|Bacteria,1VK71@1239|Firmicutes,24X6X@186801|Clostridia,3Y03E@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
NGKEMLHH_00767	411459.RUMOBE_02476	4.5e-150	422.0	COG1309@1|root,COG1309@2|Bacteria,1V6JC@1239|Firmicutes,24MPA@186801|Clostridia,3XZXC@572511|Blautia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NGKEMLHH_00768	457412.RSAG_04726	4.3e-159	446.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24KIZ@186801|Clostridia,3WKNV@541000|Ruminococcaceae	186801|Clostridia	S	MobA-like NTP transferase domain	ygfJ	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
NGKEMLHH_00769	457412.RSAG_00195	2.58e-165	462.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,3WKRV@541000|Ruminococcaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00770	457412.RSAG_00196	2.75e-212	586.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3WI66@541000|Ruminococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
NGKEMLHH_00771	1121115.AXVN01000025_gene963	4.4e-117	335.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24FZI@186801|Clostridia,3XZZI@572511|Blautia	186801|Clostridia	C	COG COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	cutS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
NGKEMLHH_00772	1121115.AXVN01000025_gene962	2.72e-204	566.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia,3XZ4A@572511|Blautia	186801|Clostridia	C	COG COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs	xdhB	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
NGKEMLHH_00773	457412.RSAG_00199	0.0	1513.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WHIV@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhA	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
NGKEMLHH_00774	457412.RSAG_02133	3.05e-57	177.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia,3WM6W@541000|Ruminococcaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NGKEMLHH_00775	1121115.AXVN01000022_gene1735	1.78e-301	824.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,24IXJ@186801|Clostridia,3Y2B7@572511|Blautia	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
NGKEMLHH_00776	1121115.AXVN01000022_gene1736	1.14e-197	549.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,3XZJU@572511|Blautia	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
NGKEMLHH_00777	457412.RSAG_02137	2.55e-247	681.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia,3WIZQ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00778	1121115.AXVN01000022_gene1738	7.07e-92	269.0	2DIZ6@1|root,32UC0@2|Bacteria,1VGDB@1239|Firmicutes,24SFK@186801|Clostridia,3Y0CW@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00779	457412.RSAG_02139	4.02e-176	489.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,3WKFF@541000|Ruminococcaceae	186801|Clostridia	S	Phosphoribosyl transferase domain	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
NGKEMLHH_00780	457412.RSAG_02140	8.74e-184	530.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3WGP3@541000|Ruminococcaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
NGKEMLHH_00781	1121115.AXVN01000038_gene3321	1.21e-302	827.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,2481G@186801|Clostridia,3XYVW@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_00782	1235792.C808_03815	1.15e-100	306.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,27I7H@186928|unclassified Lachnospiraceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_00783	1235792.C808_03815	3.51e-75	241.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,27I7H@186928|unclassified Lachnospiraceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_00784	457412.RSAG_02280	0.0	1604.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3WGRC@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NGKEMLHH_00785	457412.RSAG_02279	2.33e-142	402.0	COG0494@1|root,COG0494@2|Bacteria,1V27D@1239|Firmicutes,24GB6@186801|Clostridia,3WRQY@541000|Ruminococcaceae	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
NGKEMLHH_00786	1121115.AXVN01000038_gene3316	2.48e-13	65.5	COG1669@1|root,COG1669@2|Bacteria,1U3WZ@1239|Firmicutes,25933@186801|Clostridia,3Y22N@572511|Blautia	186801|Clostridia	S	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
NGKEMLHH_00787	1121115.AXVN01000018_gene13	7.29e-46	147.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,24QK0@186801|Clostridia,3Y0JI@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
NGKEMLHH_00788	1121115.AXVN01000018_gene14	1.44e-38	129.0	COG0690@1|root,COG0690@2|Bacteria,1VH7Y@1239|Firmicutes,24RJ1@186801|Clostridia,3Y0SS@572511|Blautia	186801|Clostridia	U	SecE/Sec61-gamma subunits of protein translocation complex	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
NGKEMLHH_00789	1121115.AXVN01000018_gene15	3.32e-119	340.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3XZ8Y@572511|Blautia	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
NGKEMLHH_00790	1121115.AXVN01000018_gene16	3.14e-89	262.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3XZUC@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
NGKEMLHH_00791	1121115.AXVN01000018_gene17	6.1e-160	448.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
NGKEMLHH_00792	457412.RSAG_01651	1.25e-239	658.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,24AQE@186801|Clostridia,3WGMZ@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
NGKEMLHH_00793	1121115.AXVN01000018_gene19	1.19e-58	183.0	2EUJQ@1|root,33N1P@2|Bacteria,1VMKN@1239|Firmicutes,250D1@186801|Clostridia,3Y0U5@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00794	457412.RSAG_01649	8.68e-129	365.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3WGYN@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
NGKEMLHH_00795	1121115.AXVN01000018_gene21	7.82e-97	281.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,3Y0CR@572511|Blautia	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
NGKEMLHH_00796	1256908.HMPREF0373_01006	9.72e-146	417.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,25Y4R@186806|Eubacteriaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
NGKEMLHH_00797	742765.HMPREF9457_03791	1.4e-260	716.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,27WFI@189330|Dorea	186801|Clostridia	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
NGKEMLHH_00798	552398.HMPREF0866_02671	0.0	1353.0	2EMVJ@1|root,33FHT@2|Bacteria,1VND6@1239|Firmicutes,24UZR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00799	552398.HMPREF0866_02669	1.16e-54	173.0	2DM60@1|root,32UG9@2|Bacteria,1VD6T@1239|Firmicutes,251MT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00800	1121115.AXVN01000002_gene1410	7.64e-131	371.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,3XZI9@572511|Blautia	186801|Clostridia	C	COG COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
NGKEMLHH_00801	457412.RSAG_00044	2.01e-208	575.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3WH30@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
NGKEMLHH_00802	457412.RSAG_00043	0.0	1052.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WHXW@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain	-	-	1.3.5.1,1.3.5.4,1.3.99.33	ko:K00239,ko:K00244,ko:K17363	ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164,R10330	RC00045,RC00669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,FMN_red
NGKEMLHH_00803	1121115.AXVN01000002_gene1407	3.15e-163	456.0	COG4656@1|root,COG4656@2|Bacteria,1UY26@1239|Firmicutes,24D3I@186801|Clostridia,3Y0XC@572511|Blautia	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_7,Fer4_9
NGKEMLHH_00804	1121115.AXVN01000002_gene1406	1.87e-215	593.0	COG0543@1|root,COG0543@2|Bacteria,1TQBZ@1239|Firmicutes,248GQ@186801|Clostridia,3Y1HE@572511|Blautia	186801|Clostridia	CH	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
NGKEMLHH_00805	1121115.AXVN01000002_gene1405	2.92e-46	157.0	COG0479@1|root,COG0479@2|Bacteria,1TP8R@1239|Firmicutes,247QI@186801|Clostridia,3Y1ET@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
NGKEMLHH_00806	411460.RUMTOR_02166	1.63e-67	204.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes,24IHH@186801|Clostridia,3XZWF@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NGKEMLHH_00807	411460.RUMTOR_02165	0.0	927.0	28HPA@1|root,2Z7XB@2|Bacteria,1TRBX@1239|Firmicutes,24AUG@186801|Clostridia,3XZ8Z@572511|Blautia	186801|Clostridia	S	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NGKEMLHH_00808	411460.RUMTOR_02163	2.13e-47	152.0	2CIZU@1|root,3323B@2|Bacteria,1VF1D@1239|Firmicutes,24QPV@186801|Clostridia,3Y0T3@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00809	411460.RUMTOR_02162	1.23e-273	748.0	COG3598@1|root,COG3598@2|Bacteria,1TU5N@1239|Firmicutes,247KK@186801|Clostridia,3Y28V@572511|Blautia	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,PriCT_1,Prim-Pol
NGKEMLHH_00810	411460.RUMTOR_02161	3.16e-31	111.0	2AQJ5@1|root,31FRY@2|Bacteria,1V6TG@1239|Firmicutes,25MZ5@186801|Clostridia,3Y0P8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00811	411460.RUMTOR_02161	6.18e-15	68.9	2AQJ5@1|root,31FRY@2|Bacteria,1V6TG@1239|Firmicutes,25MZ5@186801|Clostridia,3Y0P8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00812	411460.RUMTOR_02160	3e-63	202.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3XZN0@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NGKEMLHH_00813	411460.RUMTOR_02160	4.08e-188	526.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3XZN0@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NGKEMLHH_00814	411460.RUMTOR_02159	2.1e-37	125.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24R3P@186801|Clostridia,3Y0WT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00815	411460.RUMTOR_02158	6.6e-125	355.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24HXG@186801|Clostridia,3Y2AK@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NGKEMLHH_00816	1121115.AXVN01000004_gene1944	0.0	899.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3XYZV@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
NGKEMLHH_00817	1121115.AXVN01000004_gene1943	7.3e-121	344.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia,3XZXE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
NGKEMLHH_00818	1121115.AXVN01000004_gene1942	1.15e-116	334.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3Y095@572511|Blautia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
NGKEMLHH_00819	1121115.AXVN01000004_gene1941	3.66e-132	374.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3XZPQ@572511|Blautia	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
NGKEMLHH_00820	1121115.AXVN01000004_gene1940	9.73e-230	634.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,3Y032@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
NGKEMLHH_00821	1121115.AXVN01000193_gene1816	1.36e-288	788.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,24AH4@186801|Clostridia,3Y2B2@572511|Blautia	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NGKEMLHH_00822	887929.HMP0721_1460	4.38e-05	48.5	COG1396@1|root,COG1396@2|Bacteria,1VQQ6@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_00825	658088.HMPREF0987_01109	0.0	1504.0	COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,27J2F@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail,TMP
NGKEMLHH_00826	658088.HMPREF0987_01108	5.49e-156	437.0	28JA4@1|root,2Z94Z@2|Bacteria,1TR2M@1239|Firmicutes,24CMG@186801|Clostridia,27M0F@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00827	1121115.AXVN01000051_gene806	6.57e-226	623.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia,3Y29U@572511|Blautia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NGKEMLHH_00828	1121115.AXVN01000051_gene805	9.68e-36	121.0	2EIJI@1|root,33CAV@2|Bacteria,1VK5E@1239|Firmicutes,24MMQ@186801|Clostridia,3Y0TE@572511|Blautia	186801|Clostridia	S	COG NOG17864 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	SASP
NGKEMLHH_00829	1121115.AXVN01000051_gene804	6.14e-39	129.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,3Y0IZ@572511|Blautia	186801|Clostridia	KT	PspC domain	pspC	-	-	-	-	-	-	-	-	-	-	-	PspC
NGKEMLHH_00830	1121115.AXVN01000051_gene803	1.36e-145	419.0	2DN7I@1|root,32VZ1@2|Bacteria,1UJVJ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
NGKEMLHH_00831	1121115.AXVN01000051_gene802	2.56e-127	366.0	COG4709@1|root,COG4709@2|Bacteria,1VETQ@1239|Firmicutes,24G3G@186801|Clostridia,3Y0B4@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NGKEMLHH_00832	1121115.AXVN01000051_gene801	2.25e-70	212.0	COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,24MRF@186801|Clostridia,3Y09J@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NGKEMLHH_00833	1121115.AXVN01000036_gene2418	6.25e-77	241.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,3XZ4R@572511|Blautia	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
NGKEMLHH_00834	1121115.AXVN01000036_gene2417	1.02e-46	149.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3Y0G4@572511|Blautia	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
NGKEMLHH_00835	1121115.AXVN01000036_gene2416	7.04e-221	610.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,3XYUQ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
NGKEMLHH_00836	1121115.AXVN01000036_gene2415	6.9e-232	638.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,3XZ9I@572511|Blautia	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
NGKEMLHH_00837	1121115.AXVN01000036_gene2414	6.28e-249	684.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3XYXD@572511|Blautia	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NGKEMLHH_00838	457412.RSAG_02345	2.67e-221	610.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3WHDJ@541000|Ruminococcaceae	186801|Clostridia	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NGKEMLHH_00839	1121115.AXVN01000036_gene2412	0.0	881.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3XYSV@572511|Blautia	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NGKEMLHH_00840	1121115.AXVN01000036_gene2411	8.93e-249	683.0	COG0457@1|root,COG0457@2|Bacteria,1V4J9@1239|Firmicutes,24VUT@186801|Clostridia,3XYS1@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
NGKEMLHH_00841	1121115.AXVN01000036_gene2410	1.25e-284	779.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,3XZ8M@572511|Blautia	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
NGKEMLHH_00842	457412.RSAG_02349	0.0	1610.0	COG0695@1|root,COG1328@1|root,COG0695@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3WGUQ@541000|Ruminococcaceae	186801|Clostridia	F	TIGRFAM anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,Glutaredoxin,NRDD
NGKEMLHH_00843	1121115.AXVN01000036_gene2408	3.81e-94	275.0	COG4747@1|root,COG4747@2|Bacteria,1V8ZY@1239|Firmicutes,24NAM@186801|Clostridia,3Y0M9@572511|Blautia	186801|Clostridia	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00844	1121115.AXVN01000036_gene2407	3.95e-98	285.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3Y0EE@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NGKEMLHH_00845	1121115.AXVN01000036_gene2406	1e-218	603.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3XZJH@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NGKEMLHH_00846	1121115.AXVN01000036_gene2405	3.9e-269	735.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,3XZBE@572511|Blautia	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	trmU	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
NGKEMLHH_00847	1121115.AXVN01000036_gene2404	2.23e-314	856.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NGKEMLHH_00848	1232447.BAHW02000015_gene1070	1.73e-121	389.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,26836@186813|unclassified Clostridiales	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,HHH_4,UvrD_C_2
NGKEMLHH_00849	742723.HMPREF9477_00494	2.59e-35	129.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,27M9K@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
NGKEMLHH_00850	397288.C806_04318	1.51e-33	136.0	COG4509@1|root,COG4932@1|root,COG4509@2|Bacteria,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,2492K@186801|Clostridia,27IMP@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
NGKEMLHH_00851	883114.HMPREF9709_01536	1.03e-104	325.0	COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,25ED1@186801|Clostridia	186801|Clostridia	T	ATPase related to phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
NGKEMLHH_00852	1121864.OMO_00860	1.95e-53	184.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,4AZDR@81852|Enterococcaceae	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
NGKEMLHH_00853	457412.RSAG_02000	1.75e-174	487.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,3WHNG@541000|Ruminococcaceae	186801|Clostridia	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
NGKEMLHH_00854	457412.RSAG_02001	6.96e-243	669.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,3WIHA@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NGKEMLHH_00855	457412.RSAG_02002	1.03e-246	680.0	COG0614@1|root,COG0614@2|Bacteria,1TSAF@1239|Firmicutes,24ATS@186801|Clostridia,3WI3J@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
NGKEMLHH_00856	457412.RSAG_02003	9.28e-139	394.0	2DG4Z@1|root,2ZUIM@2|Bacteria,1V47V@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
NGKEMLHH_00857	457412.RSAG_02004	7.19e-198	548.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3WGWZ@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_00858	457412.RSAG_02005	1.36e-79	236.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,3WJYT@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NGKEMLHH_00859	1121115.AXVN01000010_gene2789	4.7e-123	352.0	COG3247@1|root,COG3247@2|Bacteria,1VFKP@1239|Firmicutes,24RBX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
NGKEMLHH_00860	457412.RSAG_01418	0.0	936.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	atsB	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
NGKEMLHH_00861	1121115.AXVN01000010_gene2791	0.0	1064.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3Y1DA@572511|Blautia	186801|Clostridia	KT	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NGKEMLHH_00862	1121115.AXVN01000010_gene2792	0.0	913.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3Y10H@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
NGKEMLHH_00863	457412.RSAG_00958	0.0	926.0	COG2508@1|root,COG2508@2|Bacteria,1TRRH@1239|Firmicutes,24C6R@186801|Clostridia,3WNTJ@541000|Ruminococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
NGKEMLHH_00864	457412.RSAG_00957	0.0	1880.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WGSH@541000|Ruminococcaceae	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	ADC,Oxidored_FMN,Pyr_redox_2
NGKEMLHH_00865	457412.RSAG_00956	4.6e-170	476.0	COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,24DU0@186801|Clostridia,3WS77@541000|Ruminococcaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
NGKEMLHH_00866	1042156.CXIVA_07990	1.25e-264	724.0	COG0582@1|root,COG0582@2|Bacteria,1TXU3@1239|Firmicutes,24C0Y@186801|Clostridia,36FWT@31979|Clostridiaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NGKEMLHH_00867	1042156.CXIVA_07980	0.0	1117.0	COG0582@1|root,COG0582@2|Bacteria,1TQQ1@1239|Firmicutes,24BI9@186801|Clostridia,36G89@31979|Clostridiaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
NGKEMLHH_00868	1042156.CXIVA_07970	0.0	976.0	COG0582@1|root,COG0582@2|Bacteria,1U0FV@1239|Firmicutes,24B44@186801|Clostridia,36NII@31979|Clostridiaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NGKEMLHH_00869	1042156.CXIVA_07960	1.45e-73	222.0	2D1NJ@1|root,33V2U@2|Bacteria,1VV01@1239|Firmicutes,25ACD@186801|Clostridia,36PT7@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00870	1042156.CXIVA_07950	3.86e-85	251.0	2C5R4@1|root,32R5C@2|Bacteria,1V57Y@1239|Firmicutes,24HAA@186801|Clostridia,36VZ3@31979|Clostridiaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NGKEMLHH_00871	1121115.AXVN01000003_gene1516	2.42e-40	133.0	2E255@1|root,32XC6@2|Bacteria,1VASU@1239|Firmicutes,25PWU@186801|Clostridia,3Y1UH@572511|Blautia	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
NGKEMLHH_00872	457412.RSAG_00590	0.0	1375.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,248PI@186801|Clostridia,3WH22@541000|Ruminococcaceae	186801|Clostridia	M	NTF2-like N-terminal transpeptidase domain	pbpC	-	3.4.16.4	ko:K05515,ko:K21467	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
NGKEMLHH_00873	457412.RSAG_00589	1.79e-289	789.0	28IBJ@1|root,2Z8E0@2|Bacteria,1UYB9@1239|Firmicutes,24BIZ@186801|Clostridia,3WP1C@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00874	411459.RUMOBE_00588	4.55e-305	831.0	28IBJ@1|root,2Z8XY@2|Bacteria,1UCWW@1239|Firmicutes,24DUG@186801|Clostridia,3XZIT@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00875	457412.RSAG_01616	0.0	1671.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3WI2B@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Glyco_hydro_31
NGKEMLHH_00876	457412.RSAG_01617	0.0	907.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia,3WHXK@541000|Ruminococcaceae	186801|Clostridia	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
NGKEMLHH_00878	1121115.AXVN01000018_gene64	1.02e-158	444.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,3XZ71@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
NGKEMLHH_00879	457412.RSAG_03044	2.33e-75	250.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,3WHTD@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
NGKEMLHH_00880	457412.RSAG_03045	1.92e-61	189.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia,3WM5W@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
NGKEMLHH_00881	1121115.AXVN01000005_gene2222	4.07e-57	177.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3Y0GX@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
NGKEMLHH_00882	457412.RSAG_03047	1.4e-251	695.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3WG8A@541000|Ruminococcaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
NGKEMLHH_00883	1121115.AXVN01000005_gene2220	9.83e-106	305.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,3Y03N@572511|Blautia	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
NGKEMLHH_00884	457412.RSAG_03049	0.0	1452.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia,3WGU9@541000|Ruminococcaceae	186801|Clostridia	L	DNA Topoisomerase IV	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
NGKEMLHH_00885	1121115.AXVN01000005_gene2218	1.56e-113	343.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia,3XYT8@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NGKEMLHH_00886	411463.EUBVEN_00921	3.11e-15	67.8	2E3ZC@1|root,32YWA@2|Bacteria,1VHZW@1239|Firmicutes,24SMN@186801|Clostridia,25XQP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00887	411469.EUBHAL_02118	1.03e-206	572.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,25VEQ@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_00888	457412.RSAG_01813	1.76e-153	431.0	2B7SS@1|root,320Z4@2|Bacteria,1V805@1239|Firmicutes,24IU3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00889	457412.RSAG_01814	1.32e-249	686.0	COG1277@1|root,COG1277@2|Bacteria,1UYRU@1239|Firmicutes,24A07@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
NGKEMLHH_00890	411470.RUMGNA_03743	3.98e-276	756.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1TRZX@1239|Firmicutes,249AI@186801|Clostridia,3XYP2@572511|Blautia	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
NGKEMLHH_00891	411469.EUBHAL_02113	6.76e-159	446.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,25YCG@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_00892	411469.EUBHAL_02129	2.49e-58	199.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,25UYY@186806|Eubacteriaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NGKEMLHH_00893	457412.RSAG_02734	1.97e-229	631.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,249GM@186801|Clostridia,3WGAM@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
NGKEMLHH_00894	457412.RSAG_02735	2.33e-184	511.0	COG0406@1|root,COG0406@2|Bacteria,1U7UE@1239|Firmicutes,24F5B@186801|Clostridia,3WI6A@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NGKEMLHH_00895	1121115.AXVN01000012_gene3103	4.8e-161	451.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,3XZHW@572511|Blautia	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
NGKEMLHH_00896	1121115.AXVN01000012_gene3104	1.78e-264	724.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,3XYYH@572511|Blautia	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NGKEMLHH_00898	411470.RUMGNA_02237	1.3e-25	120.0	COG1595@1|root,COG1595@2|Bacteria,1V8Z0@1239|Firmicutes,24KTC@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,WG_beta_rep,zinc_ribbon_2
NGKEMLHH_00902	585543.HMPREF0969_00264	3.98e-14	67.4	2FFFR@1|root,347D6@2|Bacteria,4P66C@976|Bacteroidetes,2FUIV@200643|Bacteroidia,4AS7C@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00908	1121430.JMLG01000011_gene321	3.57e-13	73.2	28MCT@1|root,2ZD18@2|Bacteria,1W49A@1239|Firmicutes,257FP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00920	1232447.BAHW02000015_gene1137	8.53e-67	214.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	prpC	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
NGKEMLHH_00922	1042163.BRLA_c001170	1.34e-18	88.2	2EUSM@1|root,33N86@2|Bacteria,1VQ8S@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00925	1232447.BAHW02000015_gene1110	6.27e-164	499.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,268SB@186813|unclassified Clostridiales	186801|Clostridia	L	DNA topoisomerase	topB1	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
NGKEMLHH_00926	457412.RSAG_01077	4.78e-79	235.0	2BB22@1|root,325BH@2|Bacteria,1URE9@1239|Firmicutes,259TU@186801|Clostridia,3WQP9@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00927	1121115.AXVN01000001_gene1057	1.49e-54	171.0	2EMJQ@1|root,32KAG@2|Bacteria,1URUU@1239|Firmicutes,259SC@186801|Clostridia,3Y0NU@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00928	1121115.AXVN01000001_gene1058	1e-101	296.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3Y099@572511|Blautia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
NGKEMLHH_00929	1121115.AXVN01000001_gene1059	5.22e-120	343.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,3XZV4@572511|Blautia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
NGKEMLHH_00930	1121115.AXVN01000001_gene1060	0.0	878.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,3XYI9@572511|Blautia	186801|Clostridia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
NGKEMLHH_00931	1121115.AXVN01000001_gene1061	1.63e-47	155.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes,257WP@186801|Clostridia,3Y0N6@572511|Blautia	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
NGKEMLHH_00932	457412.RSAG_01083	4e-140	396.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,3WIUW@541000|Ruminococcaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
NGKEMLHH_00933	457412.RSAG_01084	7.36e-55	171.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,3WJWB@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
NGKEMLHH_00934	457412.RSAG_01085	4.66e-200	555.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WGMS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
NGKEMLHH_00935	1121115.AXVN01000001_gene1065	0.0	1147.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,3XZD2@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
NGKEMLHH_00936	1121115.AXVN01000001_gene1066	0.0	1027.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3XYSE@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
NGKEMLHH_00937	1121115.AXVN01000001_gene1067	1.14e-311	851.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZAY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	mepA_10	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_00938	457412.RSAG_01089	0.0	1651.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,3WH0P@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
NGKEMLHH_00939	1121115.AXVN01000001_gene1069	0.0	1377.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3XZ5X@572511|Blautia	186801|Clostridia	J	translation elongation factor G	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
NGKEMLHH_00941	1121115.AXVN01000032_gene376	0.0	1110.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,3XYGQ@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
NGKEMLHH_00942	1121115.AXVN01000032_gene377	0.0	1521.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3XZ2A@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NGKEMLHH_00943	1121115.AXVN01000032_gene378	4.47e-187	518.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,3XYYY@572511|Blautia	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NGKEMLHH_00944	470145.BACCOP_01634	3.26e-111	319.0	2CB7B@1|root,33BRQ@2|Bacteria,4P3N1@976|Bacteroidetes,2FUWS@200643|Bacteroidia,4ASTU@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00945	470145.BACCOP_01633	1.3e-64	202.0	COG0286@1|root,COG0286@2|Bacteria,4NNGI@976|Bacteroidetes,2FPV2@200643|Bacteroidia,4AMTI@815|Bacteroidaceae	976|Bacteroidetes	V	type I restriction enzyme	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_Mtase
NGKEMLHH_00947	547042.BACCOPRO_01034	6.6e-250	687.0	2E9Q3@1|root,333WF@2|Bacteria,4NWZC@976|Bacteroidetes,2FVJC@200643|Bacteroidia,4AT1G@815|Bacteroidaceae	976|Bacteroidetes	S	TolB-like 6-blade propeller-like	-	-	-	-	-	-	-	-	-	-	-	-	TolB_like
NGKEMLHH_00948	470145.BACCOP_01458	3.54e-16	73.6	299WC@1|root,2ZWY9@2|Bacteria,4P7V6@976|Bacteroidetes,2FUR0@200643|Bacteroidia,4ASC3@815|Bacteroidaceae	976|Bacteroidetes	S	NVEALA protein	-	-	-	-	-	-	-	-	-	-	-	-	NVEALA
NGKEMLHH_00950	470145.BACCOP_01615	4.23e-78	233.0	29XI7@1|root,30J93@2|Bacteria,4PJJD@976|Bacteroidetes,2FU9X@200643|Bacteroidia,4ARSC@815|Bacteroidaceae	976|Bacteroidetes	L	Single-strand binding protein family	-	-	-	-	-	-	-	-	-	-	-	-	SSB
NGKEMLHH_00951	1029718.SFBM_1157	3.78e-69	223.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,36ESK@31979|Clostridiaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_00953	411461.DORFOR_02972	1e-45	167.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,27VVU@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
NGKEMLHH_00954	457412.RSAG_01927	1.25e-104	303.0	COG1418@1|root,COG1418@2|Bacteria,1V70P@1239|Firmicutes,24JTJ@186801|Clostridia,3WJN7@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HD
NGKEMLHH_00955	457412.RSAG_01925	1.78e-134	381.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WK21@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NGKEMLHH_00956	1121115.AXVN01000078_gene2825	0.0	1123.0	28NHG@1|root,2ZBJ9@2|Bacteria,1V1QG@1239|Firmicutes,24GQ1@186801|Clostridia,3Y0RS@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NGKEMLHH_00957	411489.CLOL250_01660	8.67e-17	75.1	295RU@1|root,30FMW@2|Bacteria,1UE97@1239|Firmicutes,25J4D@186801|Clostridia,36T0W@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
NGKEMLHH_00958	457412.RSAG_04521	1.17e-25	94.7	295RU@1|root,2ZT35@2|Bacteria,1V63F@1239|Firmicutes,24HRI@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
NGKEMLHH_00959	457412.RSAG_01470	8.5e-212	587.0	COG1396@1|root,COG1396@2|Bacteria,1V7ID@1239|Firmicutes,24DIG@186801|Clostridia	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007,HTH_3
NGKEMLHH_00960	397287.C807_01799	1.26e-08	50.8	2BEY0@1|root,328PP@2|Bacteria,1UUMP@1239|Firmicutes,25766@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00961	1121115.AXVN01000065_gene684	3.68e-152	428.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24E4Z@186801|Clostridia,3XZ3K@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yuaJ	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
NGKEMLHH_00962	457412.RSAG_01468	3.57e-112	321.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,3WJKY@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score 8.96	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
NGKEMLHH_00963	1121115.AXVN01000065_gene686	5.59e-78	232.0	COG0239@1|root,COG0239@2|Bacteria,1TTU1@1239|Firmicutes,259CY@186801|Clostridia,3Y0J4@572511|Blautia	186801|Clostridia	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
NGKEMLHH_00964	457412.RSAG_01466	8.47e-240	658.0	28M41@1|root,2ZAI3@2|Bacteria,1UZMW@1239|Firmicutes,24ANU@186801|Clostridia,3WHAM@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220
NGKEMLHH_00965	658088.HMPREF0987_01106	0.0	1158.0	28IEK@1|root,2Z8GM@2|Bacteria,1TQUU@1239|Firmicutes,24C6S@186801|Clostridia,27QWX@186928|unclassified Lachnospiraceae	186801|Clostridia	S	candidate retaining b-glycosidase, glycoside hydrolase family 5 protein K01238	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00966	658088.HMPREF0987_01105	6.8e-123	351.0	2DBDY@1|root,2Z8Q0@2|Bacteria,1UZPY@1239|Firmicutes,24BJG@186801|Clostridia,27RF8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00967	658088.HMPREF0987_01104	0.0	1195.0	COG4675@1|root,COG4675@2|Bacteria,1V63H@1239|Firmicutes,24CBR@186801|Clostridia,27K2S@186928|unclassified Lachnospiraceae	186801|Clostridia	S	the current gene model (or a revised gene model) may contain a frame shift	-	-	-	-	-	-	-	-	-	-	-	-	DUF859
NGKEMLHH_00968	658088.HMPREF0987_01103	3.06e-85	252.0	COG4824@1|root,COG4824@2|Bacteria,1V3TR@1239|Firmicutes,24HQ9@186801|Clostridia,27N2C@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
NGKEMLHH_00969	1121115.AXVN01000090_gene2570	0.0	873.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,3XZM9@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
NGKEMLHH_00970	1121115.AXVN01000090_gene2571	2.93e-138	390.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,3Y00P@572511|Blautia	186801|Clostridia	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
NGKEMLHH_00971	1121115.AXVN01000090_gene2572	3.73e-303	826.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,3XYRP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
NGKEMLHH_00972	1121115.AXVN01000012_gene3090	1.05e-179	501.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,3XZG0@572511|Blautia	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
NGKEMLHH_00973	1121115.AXVN01000012_gene3091	7.54e-40	132.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,25HV0@186801|Clostridia,3Y0TI@572511|Blautia	186801|Clostridia	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
NGKEMLHH_00974	1121115.AXVN01000051_gene800	1.36e-78	245.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,3XZ2W@572511|Blautia	186801|Clostridia	J	NOL1 NOP2 sun family protein	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
NGKEMLHH_00975	1121115.AXVN01000051_gene799	0.0	2400.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,3XYPU@572511|Blautia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
NGKEMLHH_00976	1121115.AXVN01000051_gene798	1.1e-278	790.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,3XYMT@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
NGKEMLHH_00977	1121115.AXVN01000005_gene2241	9.36e-278	758.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,3XZ23@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
NGKEMLHH_00978	457412.RSAG_03029	0.0	937.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,3WGAA@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
NGKEMLHH_00979	1121115.AXVN01000005_gene2239	1.68e-141	398.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,3XZW0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	KatE	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_00980	1121115.AXVN01000005_gene2238	9.35e-280	775.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3XZJM@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase
NGKEMLHH_00981	1121115.AXVN01000005_gene2238	4.35e-118	354.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3XZJM@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase
NGKEMLHH_00982	1121115.AXVN01000002_gene1353	2.53e-83	247.0	COG3027@1|root,COG3027@2|Bacteria,1V4E5@1239|Firmicutes,24HQR@186801|Clostridia,3Y0AS@572511|Blautia	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
NGKEMLHH_00983	457412.RSAG_00934	0.0	1463.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,3WH8K@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
NGKEMLHH_00984	1121115.AXVN01000002_gene1355	1.68e-310	848.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,3XYN1@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
NGKEMLHH_00985	457412.RSAG_04703	0.0	944.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,3WG7Q@541000|Ruminococcaceae	186801|Clostridia	M	Cell division protein FtsI penicillin-binding protein 2	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
NGKEMLHH_00986	457412.RSAG_01447	3.01e-297	809.0	COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,248GV@186801|Clostridia,3WN9Q@541000|Ruminococcaceae	186801|Clostridia	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
NGKEMLHH_00988	457412.RSAG_01448	0.0	1425.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia,3WH88@541000|Ruminococcaceae	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
NGKEMLHH_00989	457412.RSAG_01449	9.14e-316	861.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_00990	457412.RSAG_01276	0.0	864.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,3WHQS@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
NGKEMLHH_00991	1121115.AXVN01000001_gene1151	2.31e-147	415.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia,3XZ03@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
NGKEMLHH_00992	457412.RSAG_01278	0.0	974.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,3WHB7@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
NGKEMLHH_00993	457412.RSAG_01279	4.67e-259	709.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3WHN4@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
NGKEMLHH_00994	457412.RSAG_01280	5.45e-231	636.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,3WGT1@541000|Ruminococcaceae	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
NGKEMLHH_00995	457412.RSAG_01281	0.0	929.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,3WH17@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
NGKEMLHH_00996	457412.RSAG_01282	0.0	1332.0	COG2099@1|root,COG2241@1|root,COG2242@1|root,COG2099@2|Bacteria,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,3WGQY@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
NGKEMLHH_00997	457412.RSAG_01283	2.22e-173	483.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,3WHE5@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-3B	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NGKEMLHH_00998	457412.RSAG_01284	2e-264	724.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,3WHCR@541000|Ruminococcaceae	186801|Clostridia	H	Cobalamin synthesis G C-terminus	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
NGKEMLHH_00999	457412.RSAG_01285	8.69e-183	508.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,3WH3H@541000|Ruminococcaceae	186801|Clostridia	H	precorrin-4 C11-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NGKEMLHH_01000	1121115.AXVN01000001_gene1160	2.28e-272	746.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,3XYN5@572511|Blautia	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
NGKEMLHH_01001	457412.RSAG_01287	1.43e-306	837.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3WHZE@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_01002	457412.RSAG_00367	0.0	1003.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WSQQ@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NGKEMLHH_01003	1121115.AXVN01000004_gene1939	8.87e-162	453.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,3XZ4H@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_01005	1203550.HMPREF1475_00629	5.17e-83	253.0	COG2189@1|root,COG2189@2|Bacteria,4NHTG@976|Bacteroidetes,2FPXQ@200643|Bacteroidia	976|Bacteroidetes	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MerR,N6_N4_Mtase
NGKEMLHH_01006	457412.RSAG_00917	2.25e-153	433.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3WHZJ@541000|Ruminococcaceae	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
NGKEMLHH_01008	1280698.AUJS01000075_gene2134	4.47e-155	449.0	COG4972@1|root,COG4972@2|Bacteria,1UQZU@1239|Firmicutes,24VDZ@186801|Clostridia	186801|Clostridia	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01012	697329.Rumal_3412	2.63e-42	146.0	2EECP@1|root,3386X@2|Bacteria,1VHID@1239|Firmicutes,259CV@186801|Clostridia,3WPYJ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01015	720554.Clocl_0279	2.35e-20	103.0	COG3677@1|root,COG3677@2|Bacteria,1TQNY@1239|Firmicutes,249FY@186801|Clostridia,3WM50@541000|Ruminococcaceae	186801|Clostridia	L	TniQ	-	-	-	-	-	-	-	-	-	-	-	-	TniQ,TnsD
NGKEMLHH_01016	196627.cg1913	2.9e-24	101.0	2F37T@1|root,33W29@2|Bacteria,2H7B6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01020	397290.C810_01502	6.13e-14	71.6	2EDYB@1|root,337T6@2|Bacteria,1VMZH@1239|Firmicutes,24VTA@186801|Clostridia,27S7W@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01022	397291.C804_00966	3.52e-63	198.0	COG4474@1|root,COG4474@2|Bacteria,1TVSY@1239|Firmicutes,24F59@186801|Clostridia,27TUQ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF1273)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1273
NGKEMLHH_01024	471870.BACINT_00448	3.54e-181	504.0	2FH3X@1|root,348YK@2|Bacteria,4P5XN@976|Bacteroidetes,2FQ23@200643|Bacteroidia,4AQ3J@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01025	471870.BACINT_00450	1.02e-235	655.0	2BYQX@1|root,32R3T@2|Bacteria,4NQSR@976|Bacteroidetes,2FQIB@200643|Bacteroidia,4AVUZ@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01026	471870.BACINT_00452	9.43e-52	163.0	COG2336@1|root,COG2336@2|Bacteria,4NSWY@976|Bacteroidetes,2FTP1@200643|Bacteroidia,4ARPI@815|Bacteroidaceae	976|Bacteroidetes	T	Transcriptional regulator antitoxin, MazE	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
NGKEMLHH_01027	471870.BACINT_00453	1.85e-69	209.0	COG2337@1|root,COG2337@2|Bacteria,4NQA9@976|Bacteroidetes,2FU6W@200643|Bacteroidia,4ATT6@815|Bacteroidaceae	976|Bacteroidetes	L	Toxic component of a toxin-antitoxin (TA) module	mazF	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
NGKEMLHH_01028	471870.BACINT_00454	5.37e-97	281.0	28PGZ@1|root,2ZC7K@2|Bacteria,4NNBP@976|Bacteroidetes,2FS3Y@200643|Bacteroidia,4AQT3@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01029	471870.BACINT_00447	6.69e-191	533.0	2A8MX@1|root,30XQD@2|Bacteria,4PB7N@976|Bacteroidetes,2FTI2@200643|Bacteroidia,4ARPT@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01030	471870.BACINT_00449	6.89e-112	322.0	2A748@1|root,30VZY@2|Bacteria,4P9D7@976|Bacteroidetes,2FUFC@200643|Bacteroidia,4AS0J@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01032	457412.RSAG_00237	0.0	1010.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,3WGRM@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	mleN_1	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
NGKEMLHH_01033	1121115.AXVN01000017_gene255	5.09e-203	561.0	2A5RW@1|root,30UGW@2|Bacteria,1US7T@1239|Firmicutes,25A6N@186801|Clostridia,3Y26D@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01034	457412.RSAG_00239	1.43e-252	694.0	29ZQ1@1|root,327GJ@2|Bacteria,1UTCQ@1239|Firmicutes,258AP@186801|Clostridia,3WMBU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01035	457412.RSAG_00240	8.82e-293	815.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WHIV@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
NGKEMLHH_01036	742733.HMPREF9469_05015	1.05e-64	197.0	29UHU@1|root,30FUX@2|Bacteria,1UEPW@1239|Firmicutes,25JPE@186801|Clostridia,2236X@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01037	742733.HMPREF9469_05014	2.62e-27	99.0	29UJC@1|root,30FWK@2|Bacteria,1UESQ@1239|Firmicutes,25JS5@186801|Clostridia,223F7@1506553|Lachnoclostridium	186801|Clostridia	S	Phage uncharacterised protein (Phage_XkdX)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_XkdX
NGKEMLHH_01038	742733.HMPREF9469_05013	3e-108	312.0	2B236@1|root,31UK6@2|Bacteria,1UEKD@1239|Firmicutes,25JIQ@186801|Clostridia,222UF@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01039	742733.HMPREF9469_05012	1.09e-292	798.0	COG3344@1|root,COG3344@2|Bacteria,1UZGP@1239|Firmicutes,24IYK@186801|Clostridia,222J2@1506553|Lachnoclostridium	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
NGKEMLHH_01040	742733.HMPREF9469_05011	4.51e-75	224.0	2BT3T@1|root,30VXX@2|Bacteria,1U239@1239|Firmicutes,25JN1@186801|Clostridia,2232Q@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01041	742733.HMPREF9469_05010	7.29e-61	187.0	2CJIG@1|root,32SA4@2|Bacteria,1VCKV@1239|Firmicutes,24P9C@186801|Clostridia,220T9@1506553|Lachnoclostridium	186801|Clostridia	S	Phage holin family Hol44, in holin superfamily V	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_5_2
NGKEMLHH_01042	742733.HMPREF9469_05009	2.33e-129	368.0	2DV0X@1|root,33TFP@2|Bacteria,1VHIM@1239|Firmicutes,24RUM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01043	742733.HMPREF9469_05008	6.09e-53	166.0	2EXE9@1|root,33QQT@2|Bacteria,1VR5J@1239|Firmicutes,24ZD7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01044	665950.HMPREF1025_02020	1.13e-89	263.0	COG4185@1|root,COG4185@2|Bacteria,1V42Y@1239|Firmicutes,24A28@186801|Clostridia,27MGG@186928|unclassified Lachnospiraceae	186801|Clostridia	S	zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
NGKEMLHH_01045	665950.HMPREF1025_02021	8.6e-119	342.0	2EDJ2@1|root,33FID@2|Bacteria,1VKZ0@1239|Firmicutes,24FQP@186801|Clostridia,27PCF@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01046	1121115.AXVN01000016_gene3683	0.0	1174.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3XYTU@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
NGKEMLHH_01047	457412.RSAG_02368	1.72e-215	595.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,3WHV4@541000|Ruminococcaceae	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NGKEMLHH_01048	1121115.AXVN01000016_gene3681	0.0	1046.0	2EX8G@1|root,33QJ9@2|Bacteria,1VTVN@1239|Firmicutes,25FHM@186801|Clostridia,3Y0FY@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01049	1121115.AXVN01000002_gene1404	9.19e-243	665.0	COG1035@1|root,COG4656@1|root,COG1035@2|Bacteria,COG4656@2|Bacteria,1TPBM@1239|Firmicutes,24CJH@186801|Clostridia,3Y13N@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,FrhB_FdhB_C
NGKEMLHH_01050	1121115.AXVN01000002_gene1403	5.15e-109	313.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,3Y10T@572511|Blautia	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
NGKEMLHH_01051	1121115.AXVN01000002_gene1402	0.0	1292.0	COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,3Y0ZT@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,Pyr_redox_2
NGKEMLHH_01052	1121115.AXVN01000002_gene1401	1.89e-91	267.0	COG1150@1|root,COG1150@2|Bacteria,1V27J@1239|Firmicutes,24FU5@186801|Clostridia,3Y1I7@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8
NGKEMLHH_01053	1121115.AXVN01000002_gene1400	5.91e-196	542.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia,3Y1B6@572511|Blautia	186801|Clostridia	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
NGKEMLHH_01054	646529.Desaci_4551	1.25e-185	552.0	COG1112@1|root,COG1112@2|Bacteria,1TQCB@1239|Firmicutes,24E88@186801|Clostridia,266XM@186807|Peptococcaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
NGKEMLHH_01055	1121423.JONT01000047_gene2554	4.97e-153	464.0	COG4637@1|root,COG4637@2|Bacteria,1UZCB@1239|Firmicutes,248WE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
NGKEMLHH_01056	610130.Closa_2772	4.76e-152	436.0	COG4249@1|root,COG4249@2|Bacteria,1UA57@1239|Firmicutes,24CYB@186801|Clostridia	186801|Clostridia	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
NGKEMLHH_01057	1211777.BN77_2484	1.48e-54	174.0	2C8CT@1|root,315IS@2|Bacteria,1R3CJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
NGKEMLHH_01058	1196322.A370_02907	1.31e-42	145.0	2E66S@1|root,330VB@2|Bacteria,1UTN7@1239|Firmicutes,253ME@186801|Clostridia	186801|Clostridia	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
NGKEMLHH_01059	1121115.AXVN01000001_gene1070	5.93e-261	715.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,3XZI7@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
NGKEMLHH_01060	457412.RSAG_01092	1.25e-302	825.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3WG99@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
NGKEMLHH_01061	1121115.AXVN01000001_gene1072	1.15e-234	645.0	COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,249PP@186801|Clostridia,3XZ54@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,PTS-HPr
NGKEMLHH_01062	457412.RSAG_01094	6.3e-42	141.0	2F54G@1|root,33XRK@2|Bacteria,1VVDU@1239|Firmicutes,250QM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01063	1121115.AXVN01000001_gene1074	1.28e-131	373.0	COG0655@1|root,COG0655@2|Bacteria,1TQKC@1239|Firmicutes,24H9P@186801|Clostridia,3Y053@572511|Blautia	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NGKEMLHH_01064	1121115.AXVN01000001_gene1144	7.53e-250	691.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3XZ2Q@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NGKEMLHH_01065	1121115.AXVN01000001_gene1143	1.31e-151	426.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,3XZJS@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NGKEMLHH_01066	457412.RSAG_01250	0.0	971.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia,3WG8P@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
NGKEMLHH_01067	457412.RSAG_01249	3.83e-165	462.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,3WHY5@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulatory protein KdpE	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_01068	1121115.AXVN01000001_gene1140	1.68e-185	516.0	2DEAV@1|root,2ZM6Y@2|Bacteria,1V2HI@1239|Firmicutes,24GNN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01069	457412.RSAG_01246	1.65e-244	682.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3WGP1@541000|Ruminococcaceae	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NGKEMLHH_01070	457412.RSAG_01245	8.97e-293	799.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WIRI@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,NAD_binding_7,Shikimate_DH
NGKEMLHH_01071	1121115.AXVN01000001_gene1137	6.25e-112	322.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,3Y08Y@572511|Blautia	186801|Clostridia	H	precorrin-2 oxidase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
NGKEMLHH_01072	1121115.AXVN01000001_gene1136	1.65e-211	585.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,3XYIS@572511|Blautia	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
NGKEMLHH_01073	1121115.AXVN01000001_gene1135	0.0	976.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,3XZE7@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
NGKEMLHH_01074	457412.RSAG_01241	1.03e-236	650.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,3WGUW@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
NGKEMLHH_01075	1121115.AXVN01000001_gene1133	1.54e-308	840.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3XZ92@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NGKEMLHH_01076	1121115.AXVN01000001_gene1132	2.96e-266	728.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,248JF@186801|Clostridia,3XZ28@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
NGKEMLHH_01077	1121115.AXVN01000001_gene1131	2.2e-278	763.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3XZ4P@572511|Blautia	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
NGKEMLHH_01078	1121115.AXVN01000180_gene2884	1.54e-103	310.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3Y1CE@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_01079	457412.RSAG_02053	9.97e-103	297.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
NGKEMLHH_01080	1121115.AXVN01000189_gene1038	3.39e-183	510.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,3XZDC@572511|Blautia	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
NGKEMLHH_01081	457412.RSAG_02051	1.3e-104	302.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia,3WJHM@541000|Ruminococcaceae	186801|Clostridia	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
NGKEMLHH_01082	1121115.AXVN01000094_gene755	0.0	976.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,2492H@186801|Clostridia,3XZGT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	abgB	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NGKEMLHH_01083	1121115.AXVN01000004_gene1969	0.0	1825.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,3XZKX@572511|Blautia	186801|Clostridia	L	Psort location	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
NGKEMLHH_01084	457412.RSAG_00403	2.08e-264	725.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,3WH9B@541000|Ruminococcaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
NGKEMLHH_01085	1121115.AXVN01000004_gene1972	1.03e-73	226.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,3XYWN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NGKEMLHH_01086	435590.BVU_3489	1.64e-91	269.0	2A8DQ@1|root,30XFF@2|Bacteria,4PAWB@976|Bacteroidetes,2FXWJ@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01087	435590.BVU_3488	1.37e-275	751.0	COG4469@1|root,COG4469@2|Bacteria,4P4EP@976|Bacteroidetes,2FTQ2@200643|Bacteroidia,4AU2J@815|Bacteroidaceae	976|Bacteroidetes	S	Competence protein CoiA-like family	-	-	-	-	-	-	-	-	-	-	-	-	CoiA
NGKEMLHH_01088	357276.EL88_02545	8.72e-59	182.0	2DID0@1|root,302U9@2|Bacteria,4PJUW@976|Bacteroidetes,2FU0M@200643|Bacteroidia,4ARXP@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01089	435590.BVU_3486	1.26e-139	395.0	2A854@1|root,30X5W@2|Bacteria,4PAI8@976|Bacteroidetes,2FX1A@200643|Bacteroidia,4ASXH@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01090	357276.EL88_02555	3.03e-198	549.0	COG3177@1|root,COG3177@2|Bacteria,4NV5G@976|Bacteroidetes,2FQU1@200643|Bacteroidia,4AVSW@815|Bacteroidaceae	976|Bacteroidetes	L	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
NGKEMLHH_01092	457412.RSAG_02245	8.7e-197	546.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,3WHGA@541000|Ruminococcaceae	186801|Clostridia	M	Mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
NGKEMLHH_01093	457412.RSAG_02244	7.93e-60	184.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,3WKTD@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
NGKEMLHH_01094	457412.RSAG_02243	3.56e-47	151.0	COG1925@1|root,COG1925@2|Bacteria,1VWWX@1239|Firmicutes,252H5@186801|Clostridia	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01095	1121115.AXVN01000028_gene204	2.01e-212	587.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3XZVT@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NGKEMLHH_01096	457412.RSAG_02241	0.0	1367.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,3WGWI@541000|Ruminococcaceae	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
NGKEMLHH_01097	641112.ACOK01000110_gene1955	1.77e-109	390.0	COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,24X93@186801|Clostridia,3WHWE@541000|Ruminococcaceae	186801|Clostridia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01098	457412.RSAG_03029	0.0	894.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,3WGAA@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
NGKEMLHH_01099	1121115.AXVN01000005_gene2239	2.09e-130	370.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,3XZW0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	KatE	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01100	1121115.AXVN01000005_gene2238	0.0	1082.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3XZJM@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase
NGKEMLHH_01101	1121115.AXVN01000005_gene2237	5.26e-183	508.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,3XYR4@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 9.98	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
NGKEMLHH_01102	457412.RSAG_01405	0.0	908.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3WIPN@541000|Ruminococcaceae	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NGKEMLHH_01103	457412.RSAG_01404	2.3e-256	702.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WGGM@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
NGKEMLHH_01104	457412.RSAG_01403	0.0	905.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WH5M@541000|Ruminococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NGKEMLHH_01105	1121115.AXVN01000010_gene2808	1.85e-136	386.0	2EXAI@1|root,33QM6@2|Bacteria,1VU0R@1239|Firmicutes,24YTY@186801|Clostridia,3Y0G1@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01106	1121115.AXVN01000010_gene2809	2.97e-63	192.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia,3Y0DQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01107	1121115.AXVN01000114_gene1675	1.45e-76	228.0	COG1917@1|root,COG1917@2|Bacteria,1VGJQ@1239|Firmicutes,25EGC@186801|Clostridia,3Y09F@572511|Blautia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NGKEMLHH_01108	457412.RSAG_01313	1.16e-204	566.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,3WI4F@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
NGKEMLHH_01109	457412.RSAG_01314	3.18e-195	541.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,3WHB5@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
NGKEMLHH_01110	457412.RSAG_01315	1.48e-119	341.0	COG1418@1|root,COG1418@2|Bacteria,1VBWP@1239|Firmicutes,24JJV@186801|Clostridia,3WJVP@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
NGKEMLHH_01111	457412.RSAG_01316	5e-130	369.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,3WIA5@541000|Ruminococcaceae	186801|Clostridia	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
NGKEMLHH_01112	457412.RSAG_01317	1.07e-238	655.0	28I6P@1|root,2Z89K@2|Bacteria,1TSZ7@1239|Firmicutes,24AUY@186801|Clostridia,3WHKG@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01113	457412.RSAG_01318	2.95e-106	306.0	2BFEN@1|root,32988@2|Bacteria,1V9U5@1239|Firmicutes,24JWC@186801|Clostridia,3WJIN@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4869)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4869
NGKEMLHH_01114	1121115.AXVN01000004_gene2000	3.22e-60	191.0	COG0768@1|root,COG0768@2|Bacteria,1V1CI@1239|Firmicutes,24GWI@186801|Clostridia,3Y0HS@572511|Blautia	186801|Clostridia	M	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Peptidase_C70
NGKEMLHH_01115	1121115.AXVN01000004_gene1999	2.49e-166	465.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3Y09B@572511|Blautia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_01116	1121115.AXVN01000004_gene1998	1.88e-309	843.0	COG0642@1|root,COG2205@2|Bacteria,1UYAJ@1239|Firmicutes,24CIQ@186801|Clostridia,3Y01I@572511|Blautia	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,HisKA
NGKEMLHH_01117	1256908.HMPREF0373_00504	2.63e-66	211.0	COG0834@1|root,COG0834@2|Bacteria,1UYKY@1239|Firmicutes,24C0B@186801|Clostridia,25VI4@186806|Eubacteriaceae	186801|Clostridia	ET	substrate-binding protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NGKEMLHH_01118	457412.RSAG_00471	1.05e-193	550.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
NGKEMLHH_01119	411463.EUBVEN_02138	6.27e-312	851.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,25UVF@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
NGKEMLHH_01120	1256908.HMPREF0373_00094	3.55e-154	433.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,25VYC@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_01121	411461.DORFOR_00395	1.39e-173	484.0	COG4200@1|root,COG4200@2|Bacteria,1V4AY@1239|Firmicutes,24EXR@186801|Clostridia,27W6N@189330|Dorea	186801|Clostridia	S	COG NOG31276 non supervised orthologous group	mutG	-	-	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
NGKEMLHH_01122	1256908.HMPREF0373_00092	4.12e-169	473.0	COG4200@1|root,COG4200@2|Bacteria,1TRRE@1239|Firmicutes,24AHY@186801|Clostridia,25ZJG@186806|Eubacteriaceae	186801|Clostridia	S	Lantibiotic protection ABC transporter permease subunit, MutE EpiE family	-	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
NGKEMLHH_01123	1256908.HMPREF0373_00091	1.61e-163	458.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,25VRU@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
NGKEMLHH_01124	1280698.AUJS01000042_gene3279	3.69e-167	467.0	COG2265@1|root,COG2265@2|Bacteria,1UK4G@1239|Firmicutes,24H6A@186801|Clostridia,27W5R@189330|Dorea	186801|Clostridia	J	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
NGKEMLHH_01125	457412.RSAG_03003	0.0	1043.0	29WVX@1|root,30IHI@2|Bacteria,1UPZS@1239|Firmicutes,257M6@186801|Clostridia,3WIT7@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01126	1121115.AXVN01000005_gene2263	2.15e-302	827.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3XYK2@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_01127	1121115.AXVN01000005_gene2262	1.53e-161	454.0	2DPYM@1|root,333Z5@2|Bacteria,1VFMY@1239|Firmicutes,24SP4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01128	457412.RSAG_03006	3.38e-253	693.0	COG1835@1|root,COG1835@2|Bacteria,1VIE2@1239|Firmicutes,24SHJ@186801|Clostridia	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NGKEMLHH_01129	1121115.AXVN01000005_gene2260	1.71e-190	527.0	COG1278@1|root,COG1278@2|Bacteria,1URQI@1239|Firmicutes,259M3@186801|Clostridia,3Y0QB@572511|Blautia	186801|Clostridia	K	Domain of unknown function (DUF3825)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3825
NGKEMLHH_01130	1121115.AXVN01000005_gene2259	1.02e-291	796.0	COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,248EY@186801|Clostridia,3Y1FI@572511|Blautia	186801|Clostridia	KQ	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25,Methyltransf_31
NGKEMLHH_01131	457412.RSAG_03010	3.65e-220	606.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,3WGQ3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
NGKEMLHH_01132	457412.RSAG_03011	1.82e-258	707.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
NGKEMLHH_01133	1121115.AXVN01000005_gene2256	2.6e-232	638.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,3XZI0@572511|Blautia	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
NGKEMLHH_01134	457412.RSAG_03013	0.0	1212.0	COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia,3WN2E@541000|Ruminococcaceae	186801|Clostridia	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
NGKEMLHH_01135	457412.RSAG_03014	2.32e-236	650.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,3WIYW@541000|Ruminococcaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
NGKEMLHH_01136	1121115.AXVN01000005_gene2253	3.67e-149	419.0	COG1102@1|root,COG1102@2|Bacteria,1V5TS@1239|Firmicutes,24HRW@186801|Clostridia	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NGKEMLHH_01137	1121115.AXVN01000005_gene2252	3.96e-178	496.0	COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,249GD@186801|Clostridia,3Y0Y6@572511|Blautia	186801|Clostridia	S	LamB/YcsF family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
NGKEMLHH_01138	457412.RSAG_03122	0.0	924.0	COG0726@1|root,COG0726@2|Bacteria,1TWQ0@1239|Firmicutes,24BEF@186801|Clostridia,3WI2D@541000|Ruminococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
NGKEMLHH_01139	457412.RSAG_03121	0.0	915.0	COG0726@1|root,COG0726@2|Bacteria,1TWQ0@1239|Firmicutes,24BEF@186801|Clostridia,3WI2D@541000|Ruminococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
NGKEMLHH_01140	1121115.AXVN01000076_gene2630	4.19e-270	743.0	COG0544@1|root,COG0544@2|Bacteria,1V3TE@1239|Firmicutes,24AAA@186801|Clostridia,3Y00S@572511|Blautia	186801|Clostridia	M	COG COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	tig_1	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C
NGKEMLHH_01141	1121115.AXVN01000030_gene3628	1.64e-56	175.0	2E80U@1|root,3094H@2|Bacteria,1U4EU@1239|Firmicutes,2520R@186801|Clostridia,3Y1V4@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01142	1121115.AXVN01000030_gene3629	2.39e-226	623.0	COG2005@1|root,COG2068@1|root,COG2005@2|Bacteria,COG2068@2|Bacteria,1V2BH@1239|Firmicutes,25CV9@186801|Clostridia	186801|Clostridia	S	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,NTP_transf_3
NGKEMLHH_01143	1121115.AXVN01000030_gene3630	4.71e-264	722.0	COG0406@1|root,COG1418@1|root,COG0406@2|Bacteria,COG1418@2|Bacteria,1TTYI@1239|Firmicutes,25KH7@186801|Clostridia,3Y1F0@572511|Blautia	186801|Clostridia	G	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NGKEMLHH_01144	1121115.AXVN01000030_gene3631	7.29e-244	670.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,3Y1BH@572511|Blautia	186801|Clostridia	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
NGKEMLHH_01145	411459.RUMOBE_01444	1.36e-209	578.0	COG4122@1|root,COG4122@2|Bacteria,1VKRG@1239|Firmicutes,24HG7@186801|Clostridia,3Y11Q@572511|Blautia	186801|Clostridia	S	Macrocin-O-methyltransferase (TylF)	-	-	-	ko:K05303	-	-	-	-	ko00000,ko01000	-	-	-	TylF
NGKEMLHH_01147	742733.HMPREF9469_05049	8.81e-39	129.0	29UJM@1|root,30FWV@2|Bacteria,1UESZ@1239|Firmicutes,25JSE@186801|Clostridia,223G4@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01149	742733.HMPREF9469_05051	2.16e-125	362.0	arCOG05185@1|root,2Z9G9@2|Bacteria,1TZZQ@1239|Firmicutes,248TN@186801|Clostridia,21ZRK@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01153	411460.RUMTOR_01373	7.3e-62	190.0	2F7TW@1|root,34080@2|Bacteria,1VY08@1239|Firmicutes,2521H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01154	742733.HMPREF9469_05055	1.69e-195	551.0	COG0561@1|root,COG0561@2|Bacteria,1VCX4@1239|Firmicutes,24P7Y@186801|Clostridia,2210I@1506553|Lachnoclostridium	186801|Clostridia	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01155	742733.HMPREF9469_05056	6.12e-181	503.0	2CIF9@1|root,343GG@2|Bacteria,1W0TM@1239|Firmicutes,25Q1F@186801|Clostridia,21XRM@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01156	742733.HMPREF9469_05057	1.13e-38	132.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,24IH4@186801|Clostridia,21YJD@1506553|Lachnoclostridium	186801|Clostridia	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
NGKEMLHH_01157	97139.C824_03757	6.25e-177	499.0	COG0673@1|root,COG0673@2|Bacteria,1TSWE@1239|Firmicutes,24DSM@186801|Clostridia,36M2M@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NGKEMLHH_01158	1280698.AUJS01000033_gene2056	3.23e-234	655.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,27WBY@189330|Dorea	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_01159	1298920.KI911353_gene4374	8.96e-188	530.0	COG1879@1|root,COG1879@2|Bacteria,1UE0M@1239|Firmicutes,24C7Y@186801|Clostridia,2246U@1506553|Lachnoclostridium	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NGKEMLHH_01160	457412.RSAG_03088	7.57e-135	382.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3WI5H@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NGKEMLHH_01161	1121115.AXVN01000073_gene2013	2.85e-175	498.0	2EY3W@1|root,33RCQ@2|Bacteria,1VU3P@1239|Firmicutes,24XPJ@186801|Clostridia,3XZZ1@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01162	1121115.AXVN01000073_gene2014	1.62e-160	450.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,3XZ3X@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NGKEMLHH_01163	1121115.AXVN01000073_gene2015	1.12e-116	335.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3XZAV@572511|Blautia	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
NGKEMLHH_01164	1121115.AXVN01000073_gene2016	1.9e-170	475.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,3XYZ5@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
NGKEMLHH_01165	457412.RSAG_03083	7.04e-176	491.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,3WH2Z@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score 10.00	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
NGKEMLHH_01166	1121115.AXVN01000034_gene3864	0.0	958.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3XYMY@572511|Blautia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_5,Glycos_transf_1
NGKEMLHH_01167	1121115.AXVN01000034_gene3865	4.36e-156	437.0	COG0500@1|root,COG2226@2|Bacteria,1UVT3@1239|Firmicutes,25B9E@186801|Clostridia,3Y2DZ@572511|Blautia	186801|Clostridia	Q	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
NGKEMLHH_01168	1121115.AXVN01000034_gene3866	3.19e-195	540.0	COG0596@1|root,COG0596@2|Bacteria,1TSU3@1239|Firmicutes,24DYW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01169	457412.RSAG_02492	3.22e-45	153.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,24BUU@186801|Clostridia,3WJ48@541000|Ruminococcaceae	186801|Clostridia	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
NGKEMLHH_01170	1121115.AXVN01000034_gene3872	1.2e-151	426.0	COG1309@1|root,COG1309@2|Bacteria,1TT2J@1239|Firmicutes,24A5X@186801|Clostridia,3XZTU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NGKEMLHH_01171	457412.RSAG_01665	1.47e-265	727.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3WGWM@541000|Ruminococcaceae	186801|Clostridia	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NGKEMLHH_01172	457412.RSAG_01664	5.79e-251	691.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3WGWG@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NGKEMLHH_01173	457412.RSAG_01663	0.0	927.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,3WH9R@541000|Ruminococcaceae	186801|Clostridia	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
NGKEMLHH_01174	1121115.AXVN01000147_gene3491	3.54e-185	514.0	COG0463@1|root,COG0463@2|Bacteria,1TSPS@1239|Firmicutes,25FHJ@186801|Clostridia,3Y1C1@572511|Blautia	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NGKEMLHH_01175	457412.RSAG_00384	5.68e-301	820.0	COG1887@1|root,COG1887@2|Bacteria,1V2N4@1239|Firmicutes,24FU6@186801|Clostridia,3WR0Q@541000|Ruminococcaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
NGKEMLHH_01176	1121115.AXVN01000004_gene1951	2.94e-97	282.0	COG0615@1|root,COG0615@2|Bacteria,1V3KY@1239|Firmicutes,24HAQ@186801|Clostridia	186801|Clostridia	IM	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
NGKEMLHH_01177	457412.RSAG_00386	0.0	862.0	COG1887@1|root,COG1887@2|Bacteria,1V2N4@1239|Firmicutes,24FU6@186801|Clostridia,3WR0Q@541000|Ruminococcaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
NGKEMLHH_01178	1121115.AXVN01000004_gene1953	1.92e-270	737.0	COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,24EAP@186801|Clostridia	186801|Clostridia	M	Stealth protein CR2, conserved region 2	-	-	-	-	-	-	-	-	-	-	-	-	Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
NGKEMLHH_01179	1121115.AXVN01000004_gene1954	8.02e-201	560.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,3Y04U@572511|Blautia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
NGKEMLHH_01180	457412.RSAG_02479	0.0	1264.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WH14@541000|Ruminococcaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
NGKEMLHH_01181	1121115.AXVN01000101_gene821	1.44e-35	120.0	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia,3Y0SX@572511|Blautia	186801|Clostridia	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
NGKEMLHH_01182	457412.RSAG_02477	0.0	1010.0	COG1055@1|root,COG1055@2|Bacteria,1TT1V@1239|Firmicutes,24ART@186801|Clostridia	186801|Clostridia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
NGKEMLHH_01183	457412.RSAG_02476	7.56e-242	664.0	COG1102@1|root,COG1102@2|Bacteria,1TSIF@1239|Firmicutes,24BT4@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NGKEMLHH_01184	1232447.BAHW02000027_gene2060	5.59e-134	379.0	28KSD@1|root,2ZA9R@2|Bacteria,1UZZ4@1239|Firmicutes,249ZS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01185	1121333.JMLH01000050_gene632	1.12e-53	167.0	2E5HW@1|root,33098@2|Bacteria,1VFFD@1239|Firmicutes,3VS8G@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01186	457412.RSAG_04562	1.6e-40	134.0	COG1974@1|root,COG1974@2|Bacteria,1VDZS@1239|Firmicutes,25E0Q@186801|Clostridia	186801|Clostridia	L	LexA DNA binding domain	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind
NGKEMLHH_01187	411469.EUBHAL_00463	2.06e-307	837.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,25V11@186806|Eubacteriaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
NGKEMLHH_01188	1121333.JMLH01000050_gene629	3.42e-177	493.0	COG1974@1|root,COG1974@2|Bacteria,1UJ92@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
NGKEMLHH_01189	1121333.JMLH01000050_gene628	2.02e-39	130.0	COG1476@1|root,COG1476@2|Bacteria,1VCCB@1239|Firmicutes	1239|Firmicutes	K	transcriptional regulators	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NGKEMLHH_01190	1232447.BAHW02000027_gene2066	9.31e-97	281.0	COG0716@1|root,COG0716@2|Bacteria,1V72U@1239|Firmicutes,24JNK@186801|Clostridia,26B94@186813|unclassified Clostridiales	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
NGKEMLHH_01191	1121333.JMLH01000050_gene627	1.73e-79	236.0	COG2315@1|root,COG2315@2|Bacteria,1V4K7@1239|Firmicutes,3VQU7@526524|Erysipelotrichia	526524|Erysipelotrichia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
NGKEMLHH_01192	1121115.AXVN01000049_gene1309	7.29e-215	593.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,3XYS0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
NGKEMLHH_01193	457412.RSAG_02914	0.0	1168.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,3WHZQ@541000|Ruminococcaceae	186801|Clostridia	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
NGKEMLHH_01194	1121115.AXVN01000049_gene1307	0.0	1142.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,3XYVS@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	OPT
NGKEMLHH_01195	1121115.AXVN01000049_gene1306	3.11e-84	248.0	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes,24QK3@186801|Clostridia,3Y0F4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
NGKEMLHH_01196	457412.RSAG_02917	1.24e-198	551.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,25CBM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NGKEMLHH_01197	1121115.AXVN01000049_gene1304	1.19e-255	701.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,3XYND@572511|Blautia	186801|Clostridia	QT	Psort location Cytoplasmic, score 8.87	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
NGKEMLHH_01198	1121115.AXVN01000049_gene1303	7.4e-155	435.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,3XYQ6@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
NGKEMLHH_01199	1121115.AXVN01000049_gene1302	2.82e-205	569.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,3XZN5@572511|Blautia	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
NGKEMLHH_01200	1121115.AXVN01000049_gene1301	7.71e-276	755.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,3XZBV@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
NGKEMLHH_01201	457412.RSAG_02922	2.97e-210	580.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,3WGR8@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NGKEMLHH_01202	457412.RSAG_02923	0.0	1245.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,3WIIN@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
NGKEMLHH_01203	1121115.AXVN01000035_gene3845	0.0	1172.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
NGKEMLHH_01204	1121115.AXVN01000035_gene3846	8.91e-136	386.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,3XZX7@572511|Blautia	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
NGKEMLHH_01205	1121115.AXVN01000035_gene3847	3.16e-236	651.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,3XYPX@572511|Blautia	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
NGKEMLHH_01206	1121115.AXVN01000037_gene3240	0.0	1727.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
NGKEMLHH_01207	1121115.AXVN01000037_gene3241	7.06e-254	697.0	COG3347@1|root,COG3347@2|Bacteria,1TQB8@1239|Firmicutes,25BHR@186801|Clostridia,3Y16D@572511|Blautia	186801|Clostridia	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
NGKEMLHH_01208	457412.RSAG_02217	4.59e-98	299.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3WGSV@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
NGKEMLHH_01209	1121115.AXVN01000018_gene40	4.15e-186	517.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3XZFC@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
NGKEMLHH_01210	457412.RSAG_01643	1.82e-102	296.0	COG2258@1|root,COG2258@2|Bacteria,1UIYW@1239|Firmicutes,25FCC@186801|Clostridia	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
NGKEMLHH_01211	457412.RSAG_01644	1.95e-109	315.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,3WHT9@541000|Ruminococcaceae	186801|Clostridia	H	Molybdenum cofactor synthesis domain protein	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
NGKEMLHH_01212	457412.RSAG_01645	2.91e-109	314.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,3WJ9J@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
NGKEMLHH_01213	1121115.AXVN01000018_gene36	0.0	1319.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3XYH1@572511|Blautia	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
NGKEMLHH_01214	1121115.AXVN01000029_gene632	4.03e-306	840.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia,3XYZR@572511|Blautia	186801|Clostridia	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NGKEMLHH_01215	457412.RSAG_00509	7.73e-155	435.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WGVE@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_01216	457412.RSAG_00508	0.0	1179.0	COG0845@1|root,COG0845@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia,3WI0T@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
NGKEMLHH_01217	1121115.AXVN01000041_gene2600	0.0	941.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,3XYZ1@572511|Blautia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
NGKEMLHH_01218	1121115.AXVN01000041_gene2599	0.0	960.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,3XZNT@572511|Blautia	186801|Clostridia	H	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
NGKEMLHH_01219	1121115.AXVN01000041_gene2598	3.23e-59	183.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,3Y0HE@572511|Blautia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
NGKEMLHH_01220	1121115.AXVN01000041_gene2597	0.0	894.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia,3XZ7F@572511|Blautia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
NGKEMLHH_01221	1121115.AXVN01000020_gene97	1.56e-121	347.0	COG1896@1|root,COG1896@2|Bacteria,1V7E8@1239|Firmicutes,24DNC@186801|Clostridia,3Y0IJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06952	-	-	-	-	ko00000	-	-	-	DUF429,HD_3
NGKEMLHH_01222	457412.RSAG_00131	3.55e-278	761.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NGKEMLHH_01223	457412.RSAG_00132	1.52e-238	660.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,3WJ15@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
NGKEMLHH_01224	457412.RSAG_00133	1.33e-57	179.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,3WJJQ@541000|Ruminococcaceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
NGKEMLHH_01225	1121115.AXVN01000020_gene93	3.12e-178	497.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,3XZ45@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
NGKEMLHH_01226	457412.RSAG_00135	3.31e-64	216.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,3WGCH@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
NGKEMLHH_01227	180332.JTGN01000006_gene3323	1.14e-171	503.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQES@1239|Firmicutes,24C3N@186801|Clostridia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
NGKEMLHH_01228	180332.JTGN01000006_gene3324	2.19e-216	622.0	COG2972@1|root,COG2972@2|Bacteria,1UQDY@1239|Firmicutes,249HG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NGKEMLHH_01229	457412.RSAG_04728	0.0	1268.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WGTP@541000|Ruminococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
NGKEMLHH_01230	457412.RSAG_00235	1.11e-245	681.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,249SN@186801|Clostridia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,ChW,Polysacc_deac_1
NGKEMLHH_01231	457412.RSAG_00236	8.35e-141	402.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
NGKEMLHH_01232	457412.RSAG_00161	0.0	925.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,3WGSQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
NGKEMLHH_01233	457412.RSAG_00160	6.4e-315	858.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_01234	457412.RSAG_00159	1.12e-65	200.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,3WJZ3@541000|Ruminococcaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NGKEMLHH_01235	1121115.AXVN01000061_gene492	0.0	1314.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3Y0G0@572511|Blautia	186801|Clostridia	G	Putative carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
NGKEMLHH_01236	457412.RSAG_00712	8.73e-191	529.0	COG2207@1|root,COG2207@2|Bacteria,1UZ5U@1239|Firmicutes,24DJM@186801|Clostridia,3WJ5M@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
NGKEMLHH_01237	1121115.AXVN01000061_gene490	6.17e-165	460.0	COG0727@1|root,COG0727@2|Bacteria,1TT6P@1239|Firmicutes,24BWS@186801|Clostridia,3XZVI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
NGKEMLHH_01238	1121115.AXVN01000061_gene489	7.23e-85	250.0	2DRY9@1|root,33DNC@2|Bacteria,1VJXZ@1239|Firmicutes,25NY6@186801|Clostridia,3Y0SG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01239	1121115.AXVN01000061_gene488	0.0	1456.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3XYQH@572511|Blautia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
NGKEMLHH_01240	457412.RSAG_00716	2.5e-155	436.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24EFS@186801|Clostridia,3WRPD@541000|Ruminococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_01241	457412.RSAG_00717	8.37e-161	450.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,3WJUP@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
NGKEMLHH_01242	457412.RSAG_00718	1.65e-243	669.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia,3WSRI@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase like family 2	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NGKEMLHH_01243	457412.RSAG_00719	3.17e-127	368.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,3WH2W@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
NGKEMLHH_01244	1121115.AXVN01000006_gene2102	9.19e-113	331.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,3XZJ1@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
NGKEMLHH_01245	1121115.AXVN01000006_gene2103	7.1e-44	144.0	2DWAP@1|root,33ZBJ@2|Bacteria,1VWWH@1239|Firmicutes,25203@186801|Clostridia,3Y23P@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
NGKEMLHH_01246	1121115.AXVN01000006_gene2104	0.0	1040.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3XYNG@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NGKEMLHH_01247	457412.RSAG_00722	2.09e-303	829.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_01248	1121115.AXVN01000006_gene2106	0.0	868.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3XZ21@572511|Blautia	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
NGKEMLHH_01249	1410638.JHXJ01000006_gene2584	7.8e-57	194.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia,3WHUS@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
NGKEMLHH_01250	1410617.JHXH01000009_gene1644	0.0	1150.0	COG1327@1|root,COG1328@1|root,COG1327@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3WHPK@541000|Ruminococcaceae	186801|Clostridia	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
NGKEMLHH_01252	1392493.JIAB01000001_gene884	1.13e-64	206.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1V442@1239|Firmicutes,24HSE@186801|Clostridia,27MQ5@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Reverse transcriptase-like	rnhA	-	3.1.26.4	ko:K03469,ko:K06993	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
NGKEMLHH_01254	457412.RSAG_03076	1.73e-308	840.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,3WGZA@541000|Ruminococcaceae	186801|Clostridia	M	peptidoglycan binding domain protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
NGKEMLHH_01255	1469948.JPNB01000001_gene878	7.75e-56	185.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,24HE5@186801|Clostridia,36GMJ@31979|Clostridiaceae	186801|Clostridia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
NGKEMLHH_01256	1121115.AXVN01000073_gene2023	0.0	1132.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NGKEMLHH_01257	457412.RSAG_00921	0.0	1480.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
NGKEMLHH_01258	457412.RSAG_00920	8.23e-247	677.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,24E6T@186801|Clostridia	186801|Clostridia	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
NGKEMLHH_01259	457412.RSAG_00919	2.82e-100	291.0	2DHAX@1|root,32U8Z@2|Bacteria,1VV1S@1239|Firmicutes,250GD@186801|Clostridia,3WM8Y@541000|Ruminococcaceae	186801|Clostridia	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
NGKEMLHH_01260	457412.RSAG_00202	0.0	1974.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TPR4@1239|Firmicutes,248TM@186801|Clostridia,3WRQE@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain	-	-	1.97.1.9	ko:K12527	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
NGKEMLHH_01261	1121115.AXVN01000025_gene957	0.0	904.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3XZEP@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	ssnA	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NGKEMLHH_01262	457412.RSAG_02315	1.89e-134	382.0	28PIW@1|root,2ZC8Q@2|Bacteria,1V1ZT@1239|Firmicutes,24FWM@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
NGKEMLHH_01263	457412.RSAG_02316	1.16e-205	568.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3WGWZ@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_01264	397288.C806_01618	1.59e-78	234.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,27MSR@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, gntR family	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NGKEMLHH_01265	457412.RSAG_02319	1.71e-49	157.0	2CIKK@1|root,32TFN@2|Bacteria,1VAVR@1239|Firmicutes,24PS4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01266	411461.DORFOR_03297	1.45e-10	60.5	COG4679@1|root,COG4679@2|Bacteria,1VB8K@1239|Firmicutes,24KV8@186801|Clostridia,27X16@189330|Dorea	186801|Clostridia	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
NGKEMLHH_01267	457412.RSAG_03053	3.23e-218	602.0	COG4823@1|root,COG4823@2|Bacteria,1UY67@1239|Firmicutes,24CBG@186801|Clostridia,3WK78@541000|Ruminococcaceae	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
NGKEMLHH_01269	1121115.AXVN01000015_gene3744	0.0	1326.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia,3Y2CQ@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 31	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
NGKEMLHH_01270	1121115.AXVN01000015_gene3745	0.0	1330.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y0XI@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
NGKEMLHH_01271	457412.RSAG_02428	1.7e-140	397.0	COG0789@1|root,COG0789@2|Bacteria,1V1M9@1239|Firmicutes,24FUE@186801|Clostridia,3WS7D@541000|Ruminococcaceae	186801|Clostridia	K	Domain of unknown function (DUF1836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
NGKEMLHH_01273	457412.RSAG_01231	1.74e-198	556.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	FMN_bind,Flg_new,LRR_5
NGKEMLHH_01274	1121115.AXVN01000001_gene1126	0.0	934.0	COG0584@1|root,COG0584@2|Bacteria,1UVUW@1239|Firmicutes,25KN4@186801|Clostridia,3Y249@572511|Blautia	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
NGKEMLHH_01275	1121115.AXVN01000001_gene1127	2.92e-50	158.0	2FADH@1|root,342MV@2|Bacteria,1VXR1@1239|Firmicutes,252AC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01276	1121115.AXVN01000001_gene1128	0.0	882.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,3XZ9R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
NGKEMLHH_01277	1121115.AXVN01000088_gene4039	3.08e-299	823.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3XYWG@572511|Blautia	186801|Clostridia	O	COG COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NGKEMLHH_01278	457412.RSAG_03471	0.0	1597.0	COG4886@1|root,COG4886@2|Bacteria,1UKIE@1239|Firmicutes,25FXV@186801|Clostridia	186801|Clostridia	S	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
NGKEMLHH_01279	1121115.AXVN01000001_gene1082	1.92e-67	204.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,3Y0C3@572511|Blautia	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
NGKEMLHH_01280	1121115.AXVN01000001_gene1081	3.52e-309	844.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3XZA0@572511|Blautia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
NGKEMLHH_01281	1121115.AXVN01000001_gene1080	1.77e-51	162.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3Y0EA@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
NGKEMLHH_01282	1121115.AXVN01000001_gene1079	3.47e-40	133.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,3Y0D4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
NGKEMLHH_01283	457412.RSAG_01192	1.08e-113	326.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,3WIMH@541000|Ruminococcaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
NGKEMLHH_01284	1121115.AXVN01000001_gene1077	9.06e-182	505.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,3XYT2@572511|Blautia	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
NGKEMLHH_01285	742733.HMPREF9469_05064	1.47e-213	589.0	COG0286@1|root,COG0286@2|Bacteria,1V4NI@1239|Firmicutes,24HNX@186801|Clostridia,222CM@1506553|Lachnoclostridium	186801|Clostridia	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
NGKEMLHH_01286	742733.HMPREF9469_05065	3.8e-111	319.0	2E0G5@1|root,324TP@2|Bacteria,1UQZN@1239|Firmicutes,258ST@186801|Clostridia,222Q1@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01287	742733.HMPREF9469_05066	0.0	2710.0	2EWZQ@1|root,33QB0@2|Bacteria,1V0T1@1239|Firmicutes,249Z2@186801|Clostridia,221YV@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01288	742733.HMPREF9469_05067	1.25e-38	129.0	2BPQU@1|root,32II2@2|Bacteria,1UEUW@1239|Firmicutes,25JUE@186801|Clostridia,223KF@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01289	742733.HMPREF9469_05068	2.45e-44	143.0	2A7DS@1|root,30WB3@2|Bacteria,1UREQ@1239|Firmicutes,2599Z@186801|Clostridia,223EV@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01290	742733.HMPREF9469_05069	6.36e-136	384.0	2BPMG@1|root,32IEH@2|Bacteria,1V9DC@1239|Firmicutes,24MC0@186801|Clostridia,2227H@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01291	742733.HMPREF9469_05070	4.04e-125	358.0	2EGRD@1|root,33AHJ@2|Bacteria,1VMXW@1239|Firmicutes,24UKW@186801|Clostridia,222Y5@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01292	742733.HMPREF9469_05071	7.45e-30	105.0	2EH51@1|root,33AWY@2|Bacteria,1VNIM@1239|Firmicutes,24WZZ@186801|Clostridia,223HE@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01294	742733.HMPREF9469_05073	3.1e-126	360.0	COG3773@1|root,COG3773@2|Bacteria,1UEMP@1239|Firmicutes,25JKI@186801|Clostridia,222YV@1506553|Lachnoclostridium	186801|Clostridia	M	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
NGKEMLHH_01295	742733.HMPREF9469_05074	3.37e-222	613.0	2A0KC@1|root,2ZGJK@2|Bacteria,1V2JS@1239|Firmicutes,24H6R@186801|Clostridia,222B7@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01296	742733.HMPREF9469_05075	4.54e-54	169.0	29Y52@1|root,30JYA@2|Bacteria,1U4VH@1239|Firmicutes,25JNB@186801|Clostridia,2233S@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknwon function (DUF3310)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3310
NGKEMLHH_01297	742733.HMPREF9469_05076	3.44e-133	378.0	2B7V5@1|root,3211Y@2|Bacteria,1V7MK@1239|Firmicutes,24JA7@186801|Clostridia,222WR@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01298	742733.HMPREF9469_05077	8.24e-42	138.0	2EHGQ@1|root,33B8K@2|Bacteria,1VQCA@1239|Firmicutes,24WER@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01299	742733.HMPREF9469_05078	8.87e-28	103.0	2BBR4@1|root,32599@2|Bacteria,1URCS@1239|Firmicutes,2597X@186801|Clostridia,223HQ@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01300	742733.HMPREF9469_05079	2.55e-170	477.0	2A0KC@1|root,30NQJ@2|Bacteria,1V3K4@1239|Firmicutes,24HYK@186801|Clostridia,222N6@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01301	742733.HMPREF9469_05080	7.15e-199	552.0	2DJF4@1|root,305X6@2|Bacteria,1UEMJ@1239|Firmicutes,25JKE@186801|Clostridia,222YH@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01302	742733.HMPREF9469_05081	9.65e-65	197.0	291ZC@1|root,2ZPIQ@2|Bacteria,1W4SB@1239|Firmicutes,256EE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01303	742733.HMPREF9469_05082	1.42e-28	102.0	2BC63@1|root,325QX@2|Bacteria,1URR7@1239|Firmicutes,259N4@186801|Clostridia,223IY@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01304	742733.HMPREF9469_05083	4.28e-179	499.0	2A0KC@1|root,31HXF@2|Bacteria,1V8F6@1239|Firmicutes,24K13@186801|Clostridia,222V5@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01305	742733.HMPREF9469_05084	5.77e-68	206.0	2F4IW@1|root,31DGV@2|Bacteria,1TUSF@1239|Firmicutes,25948@186801|Clostridia,223FN@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01306	742733.HMPREF9469_05085	1.3e-40	134.0	2DINU@1|root,303RQ@2|Bacteria,1TV3P@1239|Firmicutes,259AD@186801|Clostridia,223MT@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01308	665950.HMPREF1025_01937	6.85e-85	249.0	2BZ9S@1|root,32R4K@2|Bacteria,1V9IB@1239|Firmicutes,24KN5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01309	457412.RSAG_00969	6.47e-45	145.0	2EJPA@1|root,33DE4@2|Bacteria,1VPMV@1239|Firmicutes,24VGY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01310	457412.RSAG_00970	0.0	1108.0	COG5421@1|root,COG5421@2|Bacteria,1UHBN@1239|Firmicutes,249CH@186801|Clostridia,3WPID@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_01311	457412.RSAG_00971	1.9e-18	75.9	COG1004@1|root,COG1004@2|Bacteria,1W2Q1@1239|Firmicutes,255WP@186801|Clostridia	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01312	457412.RSAG_00972	2.15e-174	485.0	COG1403@1|root,COG1403@2|Bacteria,1V5ES@1239|Firmicutes,24IDM@186801|Clostridia	186801|Clostridia	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
NGKEMLHH_01313	457412.RSAG_00973	4.5e-290	794.0	COG3950@1|root,COG3950@2|Bacteria,1TQIC@1239|Firmicutes,24EDD@186801|Clostridia,3WKZ3@541000|Ruminococcaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
NGKEMLHH_01314	1256908.HMPREF0373_03359	2.61e-106	308.0	COG4767@1|root,COG4767@2|Bacteria,1V7FP@1239|Firmicutes,24IQ9@186801|Clostridia,25WTP@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NGKEMLHH_01315	1256908.HMPREF0373_03360	9.94e-244	671.0	COG5002@1|root,COG5002@2|Bacteria,1TPB6@1239|Firmicutes,24AV5@186801|Clostridia,25VNN@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	vanS	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
NGKEMLHH_01316	1280698.AUJS01000019_gene1695	2.52e-205	568.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_01317	411469.EUBHAL_01197	5.24e-278	762.0	COG1277@1|root,COG1277@2|Bacteria,1TSXC@1239|Firmicutes,24CZ4@186801|Clostridia,25VPR@186806|Eubacteriaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
NGKEMLHH_01318	411469.EUBHAL_01198	1.56e-53	167.0	2AD7W@1|root,312WU@2|Bacteria,1V7M4@1239|Firmicutes,24M52@186801|Clostridia,25XDY@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01320	515620.EUBELI_20204	1.88e-27	101.0	2DPN0@1|root,332QI@2|Bacteria,1VH4E@1239|Firmicutes,24R2M@186801|Clostridia	186801|Clostridia	S	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01321	515620.EUBELI_20205	2.87e-269	743.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia,25WGH@186806|Eubacteriaceae	186801|Clostridia	EG	gluconate H symporter	-	-	-	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.4,2.A.8.1.8	-	iHN637.CLJU_RS05690,iHN637.CLJU_RS13905	GntP_permease
NGKEMLHH_01322	411470.RUMGNA_01947	1.43e-111	326.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia,3Y01S@572511|Blautia	186801|Clostridia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NGKEMLHH_01323	1121115.AXVN01000008_gene2677	1.63e-161	466.0	COG0642@1|root,COG2199@1|root,COG2199@2|Bacteria,COG2205@2|Bacteria,1UUUT@1239|Firmicutes,25KCR@186801|Clostridia,3Y1UY@572511|Blautia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NGKEMLHH_01326	97139.C824_04415	5.9e-21	96.7	2AIFZ@1|root,32WHS@2|Bacteria,1VBMM@1239|Firmicutes,25HS6@186801|Clostridia,36UA2@31979|Clostridiaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01329	318464.IO99_05385	7.27e-85	258.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,36I6U@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NGKEMLHH_01330	457412.RSAG_01224	0.0	865.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,3WGZM@541000|Ruminococcaceae	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
NGKEMLHH_01331	1121115.AXVN01000001_gene1119	3.78e-57	177.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,3Y0FS@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
NGKEMLHH_01332	1121115.AXVN01000001_gene1120	3.06e-195	540.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,3XYGN@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
NGKEMLHH_01333	457412.RSAG_01227	3.33e-140	396.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,3WJC8@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
NGKEMLHH_01334	457412.RSAG_01228	2.3e-310	865.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WGRT@541000|Ruminococcaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
NGKEMLHH_01336	411462.DORLON_00605	9.79e-106	323.0	COG4219@1|root,COG4219@2|Bacteria,1VCEX@1239|Firmicutes,24NT6@186801|Clostridia,27WUM@189330|Dorea	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
NGKEMLHH_01337	1280698.AUJS01000075_gene2139	1.08e-44	149.0	2EC8D@1|root,3366W@2|Bacteria,1VEI1@1239|Firmicutes,24SJ3@186801|Clostridia,27WYK@189330|Dorea	186801|Clostridia	S	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NGKEMLHH_01339	1121115.AXVN01000034_gene3885	5.09e-296	808.0	COG5002@1|root,COG5002@2|Bacteria,1URKI@1239|Firmicutes,248WK@186801|Clostridia,3XZE3@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NGKEMLHH_01340	1121115.AXVN01000034_gene3886	1.98e-157	441.0	COG0745@1|root,COG0745@2|Bacteria,1UZIS@1239|Firmicutes,24CCE@186801|Clostridia,3XYX9@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_01341	457412.RSAG_01296	9.18e-242	664.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia	186801|Clostridia	O	XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
NGKEMLHH_01342	457412.RSAG_01297	6.32e-274	751.0	COG1301@1|root,COG1301@2|Bacteria,1TP4N@1239|Firmicutes,2494N@186801|Clostridia,3WHRD@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
NGKEMLHH_01343	1121115.AXVN01000001_gene1171	9.5e-142	400.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,3Y06N@572511|Blautia	186801|Clostridia	O	COG NOG13230 non supervised orthologous group	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
NGKEMLHH_01344	1121115.AXVN01000001_gene1172	0.0	913.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,3XZ6S@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
NGKEMLHH_01346	742733.HMPREF9469_05046	1.35e-42	139.0	2ETJ4@1|root,33M2X@2|Bacteria,1USGT@1239|Firmicutes,25AH1@186801|Clostridia,223N3@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01349	742733.HMPREF9469_05043	1.34e-110	319.0	2E4E5@1|root,32Z9D@2|Bacteria,1VUIW@1239|Firmicutes,24F7P@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01350	742733.HMPREF9469_05042	3.54e-185	515.0	COG0501@1|root,COG0501@2|Bacteria,1UMP1@1239|Firmicutes,25GMQ@186801|Clostridia	186801|Clostridia	O	Domain of unknown function (DUF4839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4839
NGKEMLHH_01351	742733.HMPREF9469_05041	1.67e-65	199.0	2CGGB@1|root,32UNH@2|Bacteria,1VD9W@1239|Firmicutes,24MWC@186801|Clostridia,2235P@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01352	742733.HMPREF9469_05040	7.69e-134	379.0	29YRZ@1|root,30KMY@2|Bacteria,1V4Y4@1239|Firmicutes,24HPY@186801|Clostridia,221XY@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF2800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2800
NGKEMLHH_01353	457412.RSAG_02708	6.08e-106	305.0	2DV0M@1|root,32UY9@2|Bacteria,1VC55@1239|Firmicutes,24TS3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01354	457412.RSAG_02709	1.4e-113	325.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,24PEZ@186801|Clostridia,3WJE3@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NGKEMLHH_01355	457412.RSAG_02710	1.59e-308	839.0	COG1379@1|root,COG1379@2|Bacteria	2|Bacteria	-	-	yqxK	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4178,PHP_C,UvrD-helicase,UvrD_C
NGKEMLHH_01356	457412.RSAG_02711	4.06e-134	380.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,3WK2K@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
NGKEMLHH_01357	457412.RSAG_02712	3.14e-185	515.0	COG2206@1|root,COG2206@2|Bacteria,1V23X@1239|Firmicutes,24GQ5@186801|Clostridia,3WKDD@541000|Ruminococcaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
NGKEMLHH_01358	1121115.AXVN01000054_gene1881	1.14e-134	387.0	28K5V@1|root,2Z9UD@2|Bacteria,1V0GM@1239|Firmicutes,24EZ5@186801|Clostridia,3Y13M@572511|Blautia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3878
NGKEMLHH_01360	1121115.AXVN01000091_gene2603	2.21e-71	218.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia,3Y02Y@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01361	1121115.AXVN01000091_gene2604	5.7e-105	303.0	COG4506@1|root,COG4506@2|Bacteria,1V8CS@1239|Firmicutes,24JQR@186801|Clostridia,3Y0D5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
NGKEMLHH_01362	1121115.AXVN01000091_gene2605	2.61e-196	544.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,3XZR8@572511|Blautia	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
NGKEMLHH_01363	1121115.AXVN01000091_gene2606	6.51e-54	169.0	2C5NI@1|root,33W5Y@2|Bacteria,1VWK5@1239|Firmicutes,2519Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01364	1121115.AXVN01000091_gene2607	0.0	1103.0	COG0814@1|root,COG0814@2|Bacteria,1V9NE@1239|Firmicutes,25FHY@186801|Clostridia,3XZUD@572511|Blautia	186801|Clostridia	E	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
NGKEMLHH_01365	457412.RSAG_03128	0.0	941.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,3WHDF@541000|Ruminococcaceae	186801|Clostridia	EG	spore germination protein	gerA	-	-	ko:K06295,ko:K06310	-	-	-	-	ko00000	-	-	-	GerA
NGKEMLHH_01366	1121115.AXVN01000091_gene2609	4.75e-157	442.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,3XZAU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	GntR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NGKEMLHH_01367	1121115.AXVN01000091_gene2610	1.99e-205	568.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3XZ86@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
NGKEMLHH_01368	457412.RSAG_03131	0.0	998.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,3WHGK@541000|Ruminococcaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
NGKEMLHH_01369	1121115.AXVN01000091_gene2612	7.75e-94	274.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia,3Y0BV@572511|Blautia	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
NGKEMLHH_01370	1121115.AXVN01000091_gene2613	1.55e-171	479.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,3XYMN@572511|Blautia	186801|Clostridia	I	Psort location	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
NGKEMLHH_01371	1121115.AXVN01000091_gene2614	0.0	992.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,3Y0NN@572511|Blautia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_01372	1121115.AXVN01000091_gene2615	5.58e-309	841.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,24A83@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
NGKEMLHH_01373	457412.RSAG_03136	3.26e-182	511.0	COG5464@1|root,COG5464@2|Bacteria,1TYQI@1239|Firmicutes,24FIE@186801|Clostridia,3WRZY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
NGKEMLHH_01374	1392493.JIAB01000001_gene1946	3.26e-26	112.0	COG1933@1|root,COG4260@1|root,COG1933@2|Bacteria,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,27JQK@186928|unclassified Lachnospiraceae	186801|Clostridia	L	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zinc_ribbon_2
NGKEMLHH_01375	1408311.JNJM01000010_gene1050	5.31e-116	359.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,2PSJT@265975|Oribacterium	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zinc_ribbon_2
NGKEMLHH_01376	1410617.JHXH01000003_gene441	7e-115	362.0	2DBTE@1|root,2ZAXS@2|Bacteria,1TT65@1239|Firmicutes,24CSA@186801|Clostridia,3WJ8I@541000|Ruminococcaceae	186801|Clostridia	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,TIR_2
NGKEMLHH_01377	457412.RSAG_02892	9.07e-33	120.0	2FAAA@1|root,342IX@2|Bacteria,1VY2R@1239|Firmicutes,251XQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01378	1121115.AXVN01000074_gene2290	2.3e-188	523.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,3XYTK@572511|Blautia	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
NGKEMLHH_01379	457412.RSAG_02014	2.39e-141	400.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,3WIVU@541000|Ruminococcaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
NGKEMLHH_01380	457412.RSAG_02015	0.0	880.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WH3J@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NGKEMLHH_01381	1121115.AXVN01000005_gene2275	1.08e-248	682.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,3XZ8H@572511|Blautia	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
NGKEMLHH_01382	1121115.AXVN01000005_gene2274	8e-49	155.0	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes,24UDH@186801|Clostridia,3Y0TN@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
NGKEMLHH_01383	1121115.AXVN01000005_gene2273	4.53e-264	723.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3XZ7K@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
NGKEMLHH_01384	1121115.AXVN01000005_gene2272	0.0	911.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,3XYGK@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
NGKEMLHH_01385	1121115.AXVN01000004_gene1946	4.38e-102	295.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3XZYK@572511|Blautia	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
NGKEMLHH_01386	1121115.AXVN01000004_gene1947	7.57e-61	186.0	COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes,25P5S@186801|Clostridia,3Y0IV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PRC
NGKEMLHH_01387	1121115.AXVN01000004_gene1948	1.95e-175	490.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,3XZ0B@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NGKEMLHH_01388	1121115.AXVN01000004_gene1949	0.0	1497.0	COG0438@1|root,COG1887@1|root,COG0438@2|Bacteria,COG1887@2|Bacteria,1TSEW@1239|Firmicutes,25KH4@186801|Clostridia,3Y05H@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
NGKEMLHH_01389	1232443.BAIA02000114_gene2656	4.51e-54	181.0	COG2186@1|root,COG2186@2|Bacteria,1V8MT@1239|Firmicutes,24MIZ@186801|Clostridia	186801|Clostridia	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NGKEMLHH_01390	1122962.AULH01000008_gene2167	4.55e-46	154.0	2DYQS@1|root,32V5T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01391	457421.CBFG_03382	8.58e-123	357.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,26915@186813|unclassified Clostridiales	186801|Clostridia	C	Electron transfer flavoprotein domain	etfB1	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
NGKEMLHH_01392	457421.CBFG_03383	1.33e-194	550.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
NGKEMLHH_01393	1121115.AXVN01000068_gene3403	4.71e-149	419.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,3XZJ9@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
NGKEMLHH_01394	1121115.AXVN01000068_gene3404	9.69e-42	136.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia,3Y0J2@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01395	457412.RSAG_01506	3.27e-255	701.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3WIJZ@541000|Ruminococcaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
NGKEMLHH_01396	457412.RSAG_01507	0.0	947.0	COG0437@1|root,COG4624@1|root,COG0437@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,3WGZI@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
NGKEMLHH_01397	1121115.AXVN01000004_gene1929	1.24e-201	561.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3XZ5D@572511|Blautia	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NGKEMLHH_01398	1121115.AXVN01000004_gene1928	0.0	1098.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3XYR1@572511|Blautia	186801|Clostridia	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NGKEMLHH_01400	1121115.AXVN01000108_gene623	0.0	1068.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,25B1H@186801|Clostridia,3Y2A1@572511|Blautia	186801|Clostridia	KT	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NGKEMLHH_01401	457412.RSAG_01557	0.0	1163.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,24I15@186801|Clostridia,3WP5T@541000|Ruminococcaceae	186801|Clostridia	T	Cache domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NGKEMLHH_01402	1121115.AXVN01000108_gene621	5.83e-100	290.0	COG0346@1|root,COG0346@2|Bacteria,1V7XP@1239|Firmicutes,24KYI@186801|Clostridia,3Y0HK@572511|Blautia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
NGKEMLHH_01403	457412.RSAG_01409	6.37e-207	574.0	2DJUM@1|root,307DY@2|Bacteria,1U1HZ@1239|Firmicutes,24V47@186801|Clostridia,3WR1D@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
NGKEMLHH_01404	457412.RSAG_01408	4.06e-289	793.0	COG4632@1|root,COG5263@1|root,COG4632@2|Bacteria,COG5263@2|Bacteria,1TR6Z@1239|Firmicutes,25B3H@186801|Clostridia,3WJIW@541000|Ruminococcaceae	186801|Clostridia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
NGKEMLHH_01405	1121115.AXVN01000010_gene2802	1.25e-21	84.7	2CA4N@1|root,2ZQ5H@2|Bacteria,1W5T5@1239|Firmicutes,256DT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01406	1121115.AXVN01000010_gene2804	9.69e-317	861.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,3XZB7@572511|Blautia	186801|Clostridia	EK	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
NGKEMLHH_01407	552398.HMPREF0866_02677	4.12e-149	420.0	COG1136@1|root,COG1136@2|Bacteria,1TP5M@1239|Firmicutes,24BH7@186801|Clostridia,3WN76@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NGKEMLHH_01408	552398.HMPREF0866_02678	0.0	900.0	COG0577@1|root,COG0577@2|Bacteria,1TPSE@1239|Firmicutes,24BUY@186801|Clostridia,3WQA9@541000|Ruminococcaceae	186801|Clostridia	P	COG COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NGKEMLHH_01409	552398.HMPREF0866_02679	3.11e-271	744.0	COG0577@1|root,COG0577@2|Bacteria,1TR7X@1239|Firmicutes,24D3U@186801|Clostridia	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
NGKEMLHH_01410	500632.CLONEX_02467	8.68e-99	288.0	28IHS@1|root,32W97@2|Bacteria,1VB5T@1239|Firmicutes,24N44@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01411	1121115.AXVN01000006_gene2131	4.06e-211	588.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia,3XZ8A@572511|Blautia	186801|Clostridia	T	stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
NGKEMLHH_01412	1121115.AXVN01000006_gene2131	1.8e-63	204.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia,3XZ8A@572511|Blautia	186801|Clostridia	T	stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
NGKEMLHH_01413	457412.RSAG_00752	0.0	1026.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WHDP@541000|Ruminococcaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
NGKEMLHH_01414	457412.RSAG_00753	6.17e-99	288.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,3WJZ0@541000|Ruminococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
NGKEMLHH_01415	1121115.AXVN01000006_gene2134	5.1e-205	567.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,3XZAI@572511|Blautia	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
NGKEMLHH_01416	1121115.AXVN01000006_gene2135	1.89e-30	113.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3XZ0P@572511|Blautia	186801|Clostridia	J	ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
NGKEMLHH_01417	457412.RSAG_00755	9.99e-100	294.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3WGGG@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
NGKEMLHH_01418	1121115.AXVN01000006_gene2136	0.0	1234.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3XYQF@572511|Blautia	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
NGKEMLHH_01419	457412.RSAG_00757	1.02e-204	567.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,3WINP@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
NGKEMLHH_01420	1121115.AXVN01000006_gene2138	7.07e-48	153.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia,3Y0QF@572511|Blautia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
NGKEMLHH_01421	457412.RSAG_00759	1.67e-272	748.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,3WGCP@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
NGKEMLHH_01422	1121115.AXVN01000006_gene2140	5.88e-79	236.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,3Y08R@572511|Blautia	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
NGKEMLHH_01423	1121115.AXVN01000006_gene2141	8.03e-79	235.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,3Y075@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
NGKEMLHH_01424	457412.RSAG_00762	0.0	1053.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,3WGUR@541000|Ruminococcaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
NGKEMLHH_01425	457412.RSAG_00763	4.89e-160	450.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,3WITN@541000|Ruminococcaceae	186801|Clostridia	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
NGKEMLHH_01426	1121115.AXVN01000006_gene2144	1.19e-63	195.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia,3Y0J8@572511|Blautia	186801|Clostridia	S	COG NOG11553 non supervised orthologous group	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
NGKEMLHH_01427	457412.RSAG_00765	9.6e-125	356.0	29TPZ@1|root,30EY4@2|Bacteria,1UD4F@1239|Firmicutes,2591T@186801|Clostridia,3WMKP@541000|Ruminococcaceae	186801|Clostridia	S	Stage III sporulation protein AF (Spore_III_AF)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_III_AF
NGKEMLHH_01428	1121115.AXVN01000006_gene2146	1.46e-34	128.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia,3XYI3@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
NGKEMLHH_01429	1077285.AGDG01000048_gene2697	4.29e-110	328.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FQ7A@200643|Bacteroidia,4AQBJ@815|Bacteroidaceae	976|Bacteroidetes	E	Psort location Cytoplasmic, score 8.96	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NGKEMLHH_01430	357276.EL88_18135	1.14e-113	337.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FQ7A@200643|Bacteroidia,4AQBJ@815|Bacteroidaceae	976|Bacteroidetes	E	Psort location Cytoplasmic, score 8.96	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NGKEMLHH_01431	357276.EL88_18130	1.7e-87	266.0	COG1309@1|root,COG1309@2|Bacteria,4NRZ6@976|Bacteroidetes,2FQPE@200643|Bacteroidia,4AKC8@815|Bacteroidaceae	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NGKEMLHH_01432	470145.BACCOP_01579	1.65e-212	588.0	2ARP4@1|root,31GZX@2|Bacteria,4PJXX@976|Bacteroidetes,2FTE6@200643|Bacteroidia,4ARNY@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01433	470145.BACCOP_01580	4.46e-211	591.0	COG3843@1|root,COG3843@2|Bacteria,4NKF3@976|Bacteroidetes,2FP7T@200643|Bacteroidia,4AMT3@815|Bacteroidaceae	976|Bacteroidetes	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NGKEMLHH_01434	411469.EUBHAL_01615	1.9e-163	465.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,24A2X@186801|Clostridia,25WK9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NGKEMLHH_01435	457412.RSAG_04544	8.29e-93	312.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CAP,G5,SLH,fn3
NGKEMLHH_01436	1121115.AXVN01000172_gene3991	1.49e-290	794.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,24B9Q@186801|Clostridia,3XZHR@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
NGKEMLHH_01438	1121344.JHZO01000006_gene1893	3.03e-43	153.0	COG3279@1|root,COG3279@2|Bacteria,1VC5Q@1239|Firmicutes,24PUF@186801|Clostridia	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NGKEMLHH_01439	622312.ROSEINA2194_01642	7.12e-15	84.7	COG3290@1|root,COG3290@2|Bacteria,1V46S@1239|Firmicutes,24KBY@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NGKEMLHH_01440	573061.Clocel_0596	1.21e-201	571.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,36FW7@31979|Clostridiaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
NGKEMLHH_01441	457412.RSAG_02521	1.59e-129	372.0	COG0348@1|root,COG0348@2|Bacteria,1TRZZ@1239|Firmicutes,24A2P@186801|Clostridia,3WNCH@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
NGKEMLHH_01442	411470.RUMGNA_02829	8.52e-173	522.0	COG1409@1|root,COG1409@2|Bacteria,1TSSR@1239|Firmicutes,248DJ@186801|Clostridia,3Y0EJ@572511|Blautia	186801|Clostridia	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,SLH
NGKEMLHH_01443	1121115.AXVN01000029_gene654	6.6e-200	555.0	2EWQA@1|root,33TE1@2|Bacteria,1VR3E@1239|Firmicutes,24ZHT@186801|Clostridia,3Y1M8@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01444	1121115.AXVN01000029_gene653	5.17e-178	497.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3XZ9G@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
NGKEMLHH_01445	1121115.AXVN01000029_gene652	3.52e-201	559.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3XZ3B@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
NGKEMLHH_01446	1121115.AXVN01000029_gene651	8.6e-225	620.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3XZPA@572511|Blautia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
NGKEMLHH_01447	457412.RSAG_02804	0.0	1396.0	COG2234@1|root,COG2234@2|Bacteria,1TRWH@1239|Firmicutes,24BM1@186801|Clostridia,3WI61@541000|Ruminococcaceae	186801|Clostridia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
NGKEMLHH_01448	457412.RSAG_02805	1.92e-159	446.0	COG0454@1|root,COG0456@2|Bacteria,1V1I9@1239|Firmicutes,24GXQ@186801|Clostridia,3WIY4@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NGKEMLHH_01449	1121115.AXVN01000103_gene865	6.46e-83	245.0	COG3682@1|root,COG3682@2|Bacteria,1VEJ8@1239|Firmicutes	1239|Firmicutes	K	repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NGKEMLHH_01450	1121115.AXVN01000103_gene866	2.51e-19	80.9	COG1879@1|root,COG1879@2|Bacteria,1VX4B@1239|Firmicutes,251P0@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01451	457412.RSAG_00105	0.0	919.0	2DBI9@1|root,2Z9F5@2|Bacteria,1UI10@1239|Firmicutes,25E9Z@186801|Clostridia,3WIPB@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01452	1121115.AXVN01000020_gene121	4.19e-146	411.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3XYNM@572511|Blautia	186801|Clostridia	L	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
NGKEMLHH_01453	1121115.AXVN01000020_gene122	1.23e-80	239.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,3Y07Y@572511|Blautia	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
NGKEMLHH_01454	1121115.AXVN01000020_gene123	2.46e-48	158.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,3XYUN@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
NGKEMLHH_01455	457412.RSAG_02790	5.2e-188	523.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WIZI@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15586	ko02010,map02010	M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
NGKEMLHH_01456	457412.RSAG_02791	1.72e-216	598.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WN70@541000|Ruminococcaceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NGKEMLHH_01457	457412.RSAG_02792	0.0	1025.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia	186801|Clostridia	E	Family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NGKEMLHH_01458	1121115.AXVN01000059_gene418	1.64e-122	351.0	2DPBT@1|root,331F1@2|Bacteria,1UKHY@1239|Firmicutes,25FXG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01459	1121115.AXVN01000059_gene417	3.95e-191	539.0	COG5635@1|root,COG5635@2|Bacteria,1TVV2@1239|Firmicutes,25MSE@186801|Clostridia,3Y1YV@572511|Blautia	186801|Clostridia	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01460	1121115.AXVN01000059_gene441	8.09e-122	347.0	COG4767@1|root,COG4767@2|Bacteria,1VHCV@1239|Firmicutes,24RMJ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NGKEMLHH_01461	1121115.AXVN01000059_gene440	3.53e-29	103.0	COG1209@1|root,COG1209@2|Bacteria,1UU8H@1239|Firmicutes,255W3@186801|Clostridia	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01462	457412.RSAG_00179	3.4e-200	556.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,3WJ77@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
NGKEMLHH_01463	457412.RSAG_00180	2.33e-262	717.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia,3WH61@541000|Ruminococcaceae	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
NGKEMLHH_01464	1121115.AXVN01000032_gene381	0.0	973.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3XZ3J@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
NGKEMLHH_01465	457412.RSAG_01641	0.0	923.0	COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,24950@186801|Clostridia,3WIMU@541000|Ruminococcaceae	186801|Clostridia	M	Capsule synthesis protein	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
NGKEMLHH_01466	1121115.AXVN01000018_gene42	3.05e-96	281.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia,3Y09U@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
NGKEMLHH_01467	1121115.AXVN01000018_gene43	2.73e-264	724.0	COG0503@1|root,COG0503@2|Bacteria,1UZSF@1239|Firmicutes,24FUM@186801|Clostridia,3Y1E0@572511|Blautia	186801|Clostridia	F	Phosphoribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PRTase_2,TRSP
NGKEMLHH_01468	457412.RSAG_01638	7.71e-255	698.0	COG1358@1|root,COG1358@2|Bacteria,1TP5Y@1239|Firmicutes,2487J@186801|Clostridia,3WH6S@541000|Ruminococcaceae	186801|Clostridia	J	PELOTA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PELOTA_1,PRTase_1,PRTase_2,TRSP
NGKEMLHH_01469	1121115.AXVN01000018_gene45	9.06e-232	637.0	COG2301@1|root,COG2301@2|Bacteria,1TSF2@1239|Firmicutes,249TC@186801|Clostridia,3Y1G9@572511|Blautia	186801|Clostridia	G	C-C_Bond_Lyase of the TIM-Barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	C-C_Bond_Lyase
NGKEMLHH_01470	1121115.AXVN01000018_gene46	0.0	1524.0	2BVVP@1|root,2Z9CR@2|Bacteria,1TRYC@1239|Firmicutes,2487Q@186801|Clostridia,3Y1D8@572511|Blautia	186801|Clostridia	S	Putative component of 'biosynthetic module'	-	-	-	-	-	-	-	-	-	-	-	-	YceG_bac
NGKEMLHH_01471	1121115.AXVN01000018_gene47	1.02e-258	711.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3Y1EX@572511|Blautia	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
NGKEMLHH_01472	1121115.AXVN01000018_gene48	1.2e-137	389.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,3Y15Q@572511|Blautia	186801|Clostridia	T	TerD domain	terD_2	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
NGKEMLHH_01473	457412.RSAG_01633	1.26e-136	386.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,3WI1I@541000|Ruminococcaceae	186801|Clostridia	T	TerD domain	-	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
NGKEMLHH_01474	1121115.AXVN01000018_gene50	1.78e-145	409.0	COG2310@1|root,COG2310@2|Bacteria,1TR98@1239|Firmicutes,24FZM@186801|Clostridia,3Y13G@572511|Blautia	186801|Clostridia	T	TerD domain	yceC	-	-	-	-	-	-	-	-	-	-	-	TerD
NGKEMLHH_01475	1121115.AXVN01000018_gene51	0.0	1605.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3XZ0A@572511|Blautia	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
NGKEMLHH_01476	1121115.AXVN01000018_gene52	1.45e-176	493.0	COG0561@1|root,COG0561@2|Bacteria,1V24C@1239|Firmicutes,24HGT@186801|Clostridia,3Y1I1@572511|Blautia	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
NGKEMLHH_01477	411490.ANACAC_00161	1.23e-165	473.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
NGKEMLHH_01478	390333.Ldb1987	9.34e-274	766.0	COG5421@1|root,COG5421@2|Bacteria,1UHBN@1239|Firmicutes,4IRVC@91061|Bacilli,3F9JN@33958|Lactobacillaceae	91061|Bacilli	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_01479	1293597.BN147_07175	5.76e-15	69.7	29Q9G@1|root,30B8K@2|Bacteria,1U7QT@1239|Firmicutes,4IHN3@91061|Bacilli,3FA13@33958|Lactobacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01480	1232447.BAHW02000043_gene2834	1.29e-39	145.0	COG4767@1|root,COG4767@2|Bacteria,1UVJ0@1239|Firmicutes,24SMV@186801|Clostridia	186801|Clostridia	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NGKEMLHH_01482	866771.HMPREF9296_1209	3.09e-175	494.0	COG3039@1|root,COG3039@2|Bacteria,4NGHT@976|Bacteroidetes,2FNC8@200643|Bacteroidia	976|Bacteroidetes	L	Transposase IS4 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_01483	226186.BT_0280	2.35e-286	783.0	COG3328@1|root,COG3328@2|Bacteria,4NFQS@976|Bacteroidetes,2FM5A@200643|Bacteroidia,4AMKB@815|Bacteroidaceae	976|Bacteroidetes	L	COG3328 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
NGKEMLHH_01484	1121115.AXVN01000125_gene3804	2.1e-109	315.0	COG2109@1|root,COG2109@2|Bacteria,1V82Z@1239|Firmicutes,24J8J@186801|Clostridia,3Y0A2@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
NGKEMLHH_01485	1121115.AXVN01000125_gene3805	1.52e-207	574.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3XZIM@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
NGKEMLHH_01486	457412.RSAG_02224	4.28e-176	491.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,3WH3Y@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
NGKEMLHH_01487	457412.RSAG_02225	1.13e-275	757.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WGET@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NGKEMLHH_01488	1235792.C808_04003	2.34e-68	228.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,27IDT@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NGKEMLHH_01489	1235792.C808_04004	1.1e-69	239.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UCUQ@1239|Firmicutes,24FD5@186801|Clostridia,27MYJ@186928|unclassified Lachnospiraceae	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NGKEMLHH_01490	457412.RSAG_01683	0.0	1139.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WSRP@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
NGKEMLHH_01491	457412.RSAG_00734	6.99e-205	565.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,3WHRZ@541000|Ruminococcaceae	186801|Clostridia	E	histidinol phosphate phosphatase HisJ family	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
NGKEMLHH_01492	1121115.AXVN01000006_gene2115	2.84e-240	660.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
NGKEMLHH_01493	457412.RSAG_00732	4.58e-289	789.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate kinase	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
NGKEMLHH_01495	97139.C824_03759	7.82e-91	274.0	COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,24AF7@186801|Clostridia,36GBX@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
NGKEMLHH_01496	97139.C824_03760	3.24e-150	436.0	COG1879@1|root,COG1879@2|Bacteria,1TSN1@1239|Firmicutes,249RI@186801|Clostridia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NGKEMLHH_01497	887325.HMPREF0381_2858	4.71e-225	635.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,1HVMT@1164882|Lachnoanaerobaculum	186801|Clostridia	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K02056,ko:K17204	ko02010,map02010	M00221,M00590	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.11,3.A.1.2.16	-	-	ABC_tran
NGKEMLHH_01498	887325.HMPREF0381_2857	1.61e-151	434.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,1HUGI@1164882|Lachnoanaerobaculum	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NGKEMLHH_01499	1280698.AUJS01000008_gene870	2.65e-16	77.0	COG0582@1|root,COG0582@2|Bacteria,1V0BP@1239|Firmicutes,24D2Q@186801|Clostridia,27WST@189330|Dorea	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NGKEMLHH_01500	1280698.AUJS01000008_gene869	2.74e-30	115.0	COG0582@1|root,COG0582@2|Bacteria,1V78A@1239|Firmicutes,24I4Z@186801|Clostridia,27WXR@189330|Dorea	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NGKEMLHH_01501	1121115.AXVN01000018_gene28	0.0	875.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3XZZ6@572511|Blautia	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
NGKEMLHH_01502	1121115.AXVN01000018_gene29	0.0	1005.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,2482B@186801|Clostridia,3Y0RM@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
NGKEMLHH_01508	1121115.AXVN01000115_gene2458	1.19e-194	540.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,3Y01U@572511|Blautia	186801|Clostridia	D	COG COG2385 Sporulation protein and related proteins	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
NGKEMLHH_01509	1121115.AXVN01000115_gene2457	9.42e-202	560.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia,3Y09E@572511|Blautia	186801|Clostridia	M	COG COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
NGKEMLHH_01510	1121115.AXVN01000115_gene2456	7.18e-234	644.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3XZ29@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	scrR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NGKEMLHH_01511	1095750.HMPREF9970_2857	0.0	1058.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,1HWFG@1164882|Lachnoanaerobaculum	186801|Clostridia	H	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2,RVT_1
NGKEMLHH_01512	1121115.AXVN01000007_gene3548	2.79e-122	368.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,3Y16N@572511|Blautia	186801|Clostridia	U	Type IV secretion-system coupling protein DNA-binding domain	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
NGKEMLHH_01513	1121115.AXVN01000007_gene3549	2.45e-61	189.0	299KT@1|root,2ZWP8@2|Bacteria,1V5IJ@1239|Firmicutes,24N53@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01514	1121115.AXVN01000025_gene946	0.0	904.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia,3XZ1S@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
NGKEMLHH_01515	457412.RSAG_00215	4.18e-118	338.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,3WIUH@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
NGKEMLHH_01516	457412.RSAG_00216	4.47e-160	451.0	29XH2@1|root,30J7P@2|Bacteria,1VSYJ@1239|Firmicutes,259SM@186801|Clostridia,3WQM3@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01517	457412.RSAG_00217	5.58e-292	796.0	COG5279@1|root,COG5279@2|Bacteria,1TY2Q@1239|Firmicutes,24BDS@186801|Clostridia,3WRJG@541000|Ruminococcaceae	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NGKEMLHH_01518	140626.JHWB01000022_gene2089	5.93e-27	110.0	28KBJ@1|root,2Z9YJ@2|Bacteria,1V10F@1239|Firmicutes,24WPP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01521	1235799.C818_01939	1.31e-91	274.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,27K3J@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_01523	1504823.CCMM01000012_gene2215	1.08e-15	78.6	28MKK@1|root,2ZAWR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RNA_helicase,Viral_Rep
NGKEMLHH_01525	1168289.AJKI01000022_gene1854	4.39e-64	199.0	COG3727@1|root,COG3727@2|Bacteria,4NQEH@976|Bacteroidetes,2FT9A@200643|Bacteroidia	976|Bacteroidetes	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
NGKEMLHH_01526	642492.Clole_0233	4.47e-114	347.0	COG0270@1|root,COG0270@2|Bacteria,1TR40@1239|Firmicutes,24A8V@186801|Clostridia	186801|Clostridia	H	Cytosine-specific methyltransferase	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
NGKEMLHH_01527	585543.HMPREF0969_00204	3.18e-149	459.0	arCOG06613@1|root,2Z7VT@2|Bacteria,4NFYT@976|Bacteroidetes,2FR8U@200643|Bacteroidia,4ARJY@815|Bacteroidaceae	976|Bacteroidetes	S	AIPR protein	-	-	-	-	-	-	-	-	-	-	-	-	AIPR
NGKEMLHH_01528	860228.Ccan_00300	8.36e-66	216.0	arCOG12551@1|root,2Z9WJ@2|Bacteria,4NM2Z@976|Bacteroidetes,1ID9X@117743|Flavobacteriia,1ESS8@1016|Capnocytophaga	976|Bacteroidetes	S	Putative  PD-(D/E)XK family member, (DUF4420)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4420
NGKEMLHH_01529	860228.Ccan_00310	5.45e-229	679.0	COG1100@1|root,COG1100@2|Bacteria,4NHD1@976|Bacteroidetes,1HZW7@117743|Flavobacteriia,1ESR2@1016|Capnocytophaga	976|Bacteroidetes	L	Z1 domain	-	-	-	-	-	-	-	-	-	-	-	-	ResIII,Z1
NGKEMLHH_01530	553178.CAPGI0001_0243	1.5e-170	497.0	COG0323@1|root,COG0323@2|Bacteria,4NGM8@976|Bacteroidetes,1ID1D@117743|Flavobacteriia,1ESZ4@1016|Capnocytophaga	976|Bacteroidetes	L	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
NGKEMLHH_01533	1378168.N510_00587	1.26e-109	331.0	COG1066@1|root,COG1066@2|Bacteria,1UHUE@1239|Firmicutes	1239|Firmicutes	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
NGKEMLHH_01534	1540257.JQMW01000005_gene262	1.57e-08	53.5	2DJY1@1|root,307TR@2|Bacteria,1V50J@1239|Firmicutes,24UP5@186801|Clostridia,36PW7@31979|Clostridiaceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
NGKEMLHH_01535	768710.DesyoDRAFT_4395	2.12e-81	267.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,265SK@186807|Peptococcaceae	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Relaxase
NGKEMLHH_01537	658086.HMPREF0994_05182	3.09e-155	462.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27J4S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_01539	536227.CcarbDRAFT_4922	1.38e-103	316.0	COG1479@1|root,COG1479@2|Bacteria,1VHC8@1239|Firmicutes,24PSV@186801|Clostridia,36W3S@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
NGKEMLHH_01540	904306.HMPREF9192_1916	1.31e-23	90.5	2DQKF@1|root,337FN@2|Bacteria,1VN73@1239|Firmicutes,4HSEG@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01543	1158604.I591_02854	5.74e-49	162.0	COG2214@1|root,COG2214@2|Bacteria,1V7Z6@1239|Firmicutes,4HW1S@91061|Bacilli,4AZSE@81852|Enterococcaceae	91061|Bacilli	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
NGKEMLHH_01545	1121115.AXVN01000031_gene334	0.0	958.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,3XZKK@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
NGKEMLHH_01546	1121115.AXVN01000031_gene333	6.18e-289	789.0	COG1408@1|root,COG1408@2|Bacteria,1TS43@1239|Firmicutes,248XA@186801|Clostridia,3XZND@572511|Blautia	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NGKEMLHH_01547	1121115.AXVN01000031_gene332	2.38e-122	349.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,3XZW9@572511|Blautia	186801|Clostridia	K	COG COG2002 Regulators of stationary sporulation gene expression	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
NGKEMLHH_01548	1121115.AXVN01000031_gene330	0.0	1399.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3XYX5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pbg	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NGKEMLHH_01549	457412.RSAG_03199	9.48e-237	651.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia,3WK12@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NGKEMLHH_01550	1121115.AXVN01000031_gene322	1.24e-31	110.0	2CA4Q@1|root,349NE@2|Bacteria,1VYK2@1239|Firmicutes,253VZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01551	457412.RSAG_03201	9.44e-189	524.0	COG1192@1|root,COG1192@2|Bacteria,1UPGE@1239|Firmicutes,24A5R@186801|Clostridia,3WPYK@541000|Ruminococcaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,HTH_3
NGKEMLHH_01552	1121115.AXVN01000115_gene2450	3.1e-154	433.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,3XYGI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
NGKEMLHH_01553	457412.RSAG_03203	4.2e-179	504.0	COG5263@1|root,COG5263@2|Bacteria,1UJWN@1239|Firmicutes,25FCE@186801|Clostridia,3WKY6@541000|Ruminococcaceae	186801|Clostridia	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
NGKEMLHH_01554	1121115.AXVN01000115_gene2453	5.28e-53	166.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,3Y0F0@572511|Blautia	186801|Clostridia	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
NGKEMLHH_01555	1121115.AXVN01000115_gene2454	0.0	998.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3XZ5W@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	scrB	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
NGKEMLHH_01556	1121115.AXVN01000115_gene2455	0.0	1217.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,3XZ3A@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	2.7.1.211	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
NGKEMLHH_01557	457412.RSAG_01425	1.62e-214	604.0	COG2972@1|root,COG2972@2|Bacteria,1U6WN@1239|Firmicutes,24CTB@186801|Clostridia,3WJZ8@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NGKEMLHH_01558	457412.RSAG_01426	0.0	1035.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UCUQ@1239|Firmicutes,24FD5@186801|Clostridia,3WPDP@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NGKEMLHH_01559	1121115.AXVN01000010_gene2781	0.0	890.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZMN@572511|Blautia	186801|Clostridia	T	Single Cache-like	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
NGKEMLHH_01560	1121115.AXVN01000081_gene3054	3.16e-284	781.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,3XZGY@572511|Blautia	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
NGKEMLHH_01561	1121115.AXVN01000081_gene3053	1.13e-171	480.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,3XZ2M@572511|Blautia	186801|Clostridia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
NGKEMLHH_01563	1121115.AXVN01000081_gene3052	6.52e-292	796.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,3XYS6@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
NGKEMLHH_01564	1226322.HMPREF1545_03055	2.52e-05	57.4	COG2304@1|root,COG4447@1|root,COG2304@2|Bacteria,COG4447@2|Bacteria,1UMX3@1239|Firmicutes,24G9V@186801|Clostridia,2N8X5@216572|Oscillospiraceae	186801|Clostridia	S	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
NGKEMLHH_01566	1304866.K413DRAFT_2107	3.46e-33	121.0	COG1959@1|root,COG1959@2|Bacteria,1V6U4@1239|Firmicutes,25CBZ@186801|Clostridia,36JUK@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NGKEMLHH_01567	941824.TCEL_02096	3.28e-88	276.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,36DIE@31979|Clostridiaceae	186801|Clostridia	G	ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
NGKEMLHH_01568	1235800.C819_00746	6.79e-31	132.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,27IA2@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and or methyl galactoside import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NGKEMLHH_01569	553973.CLOHYLEM_05759	4.75e-102	308.0	COG2972@1|root,COG2972@2|Bacteria,1TRKI@1239|Firmicutes,24B7C@186801|Clostridia,21XPV@1506553|Lachnoclostridium	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
NGKEMLHH_01570	1122915.AUGY01000096_gene3683	5.12e-192	564.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,4HARI@91061|Bacilli,26SRJ@186822|Paenibacillaceae	91061|Bacilli	G	beta-galactosidase	pbg	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NGKEMLHH_01571	1121115.AXVN01000014_gene1241	2.23e-283	773.0	COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,247W5@186801|Clostridia,3Y0AK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	mdh	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
NGKEMLHH_01572	457412.RSAG_01677	4.05e-93	273.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,3WKS1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
NGKEMLHH_01573	457412.RSAG_02990	2.43e-32	124.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3WGKN@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase III	traI	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
NGKEMLHH_01574	457412.RSAG_02989	4.94e-142	402.0	COG1207@1|root,COG1207@2|Bacteria,1UHDT@1239|Firmicutes,25Q4M@186801|Clostridia,3WH51@541000|Ruminococcaceae	186801|Clostridia	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
NGKEMLHH_01575	457412.RSAG_02988	2.94e-184	511.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,3WK2R@541000|Ruminococcaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
NGKEMLHH_01576	1121115.AXVN01000005_gene2280	6.9e-166	463.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,3XYM6@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
NGKEMLHH_01577	1121115.AXVN01000005_gene2281	3.06e-238	655.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
NGKEMLHH_01578	1121115.AXVN01000063_gene705	0.0	1083.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3XYH9@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
NGKEMLHH_01579	457412.RSAG_02103	2.16e-239	658.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WGRJ@541000|Ruminococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
NGKEMLHH_01580	457412.RSAG_02102	9.95e-216	596.0	COG1910@1|root,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,3WHAS@541000|Ruminococcaceae	186801|Clostridia	P	TIGRFAM DNA binding domain	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_17,PBP_like
NGKEMLHH_01581	1121115.AXVN01000063_gene708	2.67e-39	130.0	COG3585@1|root,COG3585@2|Bacteria,1VEPR@1239|Firmicutes,24QTI@186801|Clostridia	186801|Clostridia	H	pfam tobe	mopI	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	TOBE
NGKEMLHH_01582	1121115.AXVN01000113_gene2366	1.98e-198	551.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3XZ40@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NGKEMLHH_01583	1121115.AXVN01000113_gene2367	5.78e-139	394.0	2B7SS@1|root,320Z4@2|Bacteria,1V805@1239|Firmicutes,24IU3@186801|Clostridia,3Y0PA@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01584	411461.DORFOR_02714	1.07e-220	613.0	COG1277@1|root,COG1277@2|Bacteria,1UYRU@1239|Firmicutes,24A07@186801|Clostridia,27WQ5@189330|Dorea	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
NGKEMLHH_01585	411461.DORFOR_02715	2.71e-247	683.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1TRZX@1239|Firmicutes,249AI@186801|Clostridia,27W6U@189330|Dorea	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NGKEMLHH_01586	1121115.AXVN01000046_gene2983	4.85e-136	386.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
NGKEMLHH_01587	1121115.AXVN01000046_gene2984	1.77e-149	420.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3XZ95@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
NGKEMLHH_01588	1121115.AXVN01000046_gene2985	3.91e-66	201.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,3XZZ4@572511|Blautia	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
NGKEMLHH_01589	1121115.AXVN01000046_gene2986	1.58e-233	647.0	COG0681@1|root,COG0681@2|Bacteria,1VGJ6@1239|Firmicutes,24SUY@186801|Clostridia,3Y28M@572511|Blautia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01590	1244531.CIG1485E_0317	1.51e-43	149.0	2CEMV@1|root,33MP0@2|Bacteria	2|Bacteria	L	Bsp6I restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_Bsp6I
NGKEMLHH_01591	883077.HMPREF9241_00263	6.66e-150	431.0	COG0270@1|root,COG0270@2|Bacteria,2GJR6@201174|Actinobacteria,4D3D0@85005|Actinomycetales	201174|Actinobacteria	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,HTH_3
NGKEMLHH_01592	658088.HMPREF0987_01154	9.5e-52	163.0	29U5P@1|root,30FFC@2|Bacteria,1UDZ5@1239|Firmicutes,25ITF@186801|Clostridia,27SPS@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01593	658088.HMPREF0987_01153	2.5e-52	165.0	29U5P@1|root,30FFC@2|Bacteria,1UDZ5@1239|Firmicutes,25ITF@186801|Clostridia,27SPS@186928|unclassified Lachnospiraceae	658088.HMPREF0987_01153|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01595	658088.HMPREF0987_01151	2.12e-136	385.0	COG2856@1|root,COG2856@2|Bacteria,1V7P2@1239|Firmicutes,24EAH@186801|Clostridia,27P8Y@186928|unclassified Lachnospiraceae	186801|Clostridia	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
NGKEMLHH_01596	658088.HMPREF0987_01150	1.51e-69	210.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24UEE@186801|Clostridia,27PYX@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_01597	457412.RSAG_01884	0.0	1172.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WGKA@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
NGKEMLHH_01598	457412.RSAG_01885	1.29e-231	636.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1UVPR@1239|Firmicutes,25KKF@186801|Clostridia,3WPZY@541000|Ruminococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NGKEMLHH_01599	457412.RSAG_01886	4.24e-310	843.0	COG1653@1|root,COG1653@2|Bacteria,1TQJU@1239|Firmicutes,24AHT@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_01600	457412.RSAG_01887	9.51e-295	801.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,249GP@186801|Clostridia,3WHHT@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
NGKEMLHH_01601	457412.RSAG_01888	1.14e-196	546.0	COG0395@1|root,COG0395@2|Bacteria,1TSJ9@1239|Firmicutes,24ERB@186801|Clostridia	186801|Clostridia	P	abc transporter permease protein	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_01602	457412.RSAG_01889	8.47e-207	572.0	COG1175@1|root,COG1175@2|Bacteria,1UXJV@1239|Firmicutes,25MIZ@186801|Clostridia,3WQ0J@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_01603	457412.RSAG_01890	4.53e-303	825.0	COG1653@1|root,COG1653@2|Bacteria,1TQJU@1239|Firmicutes,24AHT@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NGKEMLHH_01604	457412.RSAG_01891	0.0	1191.0	COG2972@1|root,COG2972@2|Bacteria,1TSE1@1239|Firmicutes,24B0H@186801|Clostridia	186801|Clostridia	T	HAMP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NGKEMLHH_01605	457412.RSAG_01892	0.0	1051.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TR4U@1239|Firmicutes,24JVF@186801|Clostridia,3WJ1J@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
NGKEMLHH_01606	1121115.AXVN01000156_gene544	1.12e-174	489.0	COG4822@1|root,COG4822@2|Bacteria	2|Bacteria	H	anaerobic cobalamin biosynthetic process	cbiK	-	4.99.1.3	ko:K02006,ko:K02190	ko00860,ko01100,ko02010,map00860,map01100,map02010	M00245,M00246	R05807	RC01012	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran,CbiK,TP_methylase
NGKEMLHH_01607	1121115.AXVN01000156_gene545	2.08e-112	323.0	COG5652@1|root,COG5652@2|Bacteria,1V72A@1239|Firmicutes,259NP@186801|Clostridia,3Y02J@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NGKEMLHH_01608	1121115.AXVN01000156_gene546	2.54e-95	279.0	2979U@1|root,2ZUHG@2|Bacteria,1W35F@1239|Firmicutes,256C8@186801|Clostridia,3Y0TR@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01609	457412.RSAG_00111	3.57e-120	343.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3WJZ9@541000|Ruminococcaceae	186801|Clostridia	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
NGKEMLHH_01610	457412.RSAG_00110	5.93e-261	715.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,3WGPK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
NGKEMLHH_01611	457412.RSAG_00109	1.06e-179	500.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,3WJ3J@541000|Ruminococcaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
NGKEMLHH_01612	1121115.AXVN01000020_gene118	5.92e-109	318.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,3XZSZ@572511|Blautia	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
NGKEMLHH_01613	1121115.AXVN01000020_gene119	2.91e-16	75.1	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3XYQJ@572511|Blautia	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
NGKEMLHH_01615	1121115.AXVN01000018_gene22	0.0	923.0	COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,24ADD@186801|Clostridia,3Y0F7@572511|Blautia	186801|Clostridia	S	Archaea bacterial proteins of unknown function	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
NGKEMLHH_01616	585394.RHOM_15360	1.46e-173	496.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248K6@186801|Clostridia	186801|Clostridia	L	DNA polymerase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
NGKEMLHH_01617	1280698.AUJS01000008_gene871	8.43e-18	80.9	COG4974@1|root,COG4974@2|Bacteria,1TS3U@1239|Firmicutes,24EMD@186801|Clostridia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
NGKEMLHH_01618	1121115.AXVN01000018_gene26	7.47e-174	484.0	COG4974@1|root,COG4974@2|Bacteria,1TS3U@1239|Firmicutes,24EMD@186801|Clostridia,3Y2BD@572511|Blautia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
NGKEMLHH_01620	457412.RSAG_01356	0.0	1082.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,3WGE8@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
NGKEMLHH_01621	1121115.AXVN01000002_gene1383	1.06e-80	239.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,3XZDT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
NGKEMLHH_01622	1121115.AXVN01000002_gene1382	3.22e-140	395.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,3XYJ4@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
NGKEMLHH_01623	1121115.AXVN01000002_gene1381	6.73e-303	827.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,3XZ14@572511|Blautia	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
NGKEMLHH_01624	1121115.AXVN01000002_gene1380	1.76e-147	416.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia,3XZ1U@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
NGKEMLHH_01625	1121115.AXVN01000002_gene1379	1.17e-163	464.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,3XYWI@572511|Blautia	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
NGKEMLHH_01626	411459.RUMOBE_02478	7.95e-221	609.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,3XYS0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
NGKEMLHH_01627	411459.RUMOBE_02479	0.0	1152.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,3XZDU@572511|Blautia	186801|Clostridia	P	NorD protein required for nitric oxide reductase (Nor) activity	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
NGKEMLHH_01629	411459.RUMOBE_02481	2.91e-171	479.0	COG3640@1|root,COG3640@2|Bacteria,1V308@1239|Firmicutes,24H11@186801|Clostridia	186801|Clostridia	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
NGKEMLHH_01630	457412.RSAG_01825	8.02e-228	627.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia,3WHUS@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
NGKEMLHH_01631	457412.RSAG_01826	7.33e-289	790.0	COG0265@1|root,COG0265@2|Bacteria,1TTAZ@1239|Firmicutes,24BWH@186801|Clostridia,3WJ2P@541000|Ruminococcaceae	186801|Clostridia	O	Trypsin-like peptidase domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NGKEMLHH_01632	457412.RSAG_02325	7.48e-171	476.0	COG1489@1|root,COG1489@2|Bacteria,1VTYF@1239|Firmicutes,25E56@186801|Clostridia,3WS62@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
NGKEMLHH_01633	457412.RSAG_02324	7.78e-158	442.0	28HPF@1|root,2Z98R@2|Bacteria,1UZQH@1239|Firmicutes,24DVV@186801|Clostridia,3WRZF@541000|Ruminococcaceae	186801|Clostridia	S	RloB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	RloB
NGKEMLHH_01634	457412.RSAG_02323	0.0	881.0	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,249DS@186801|Clostridia,3WJY3@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
NGKEMLHH_01635	1121115.AXVN01000011_gene3438	2.24e-185	526.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia,3XZC2@572511|Blautia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_01636	1280688.AUJB01000008_gene932	4.32e-10	56.6	2ESD1@1|root,33JXT@2|Bacteria,1VKX9@1239|Firmicutes,24WEQ@186801|Clostridia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NGKEMLHH_01637	1321815.HMPREF9193_01913	6.31e-23	90.5	COG2161@1|root,COG2161@2|Bacteria,2J8HG@203691|Spirochaetes	203691|Spirochaetes	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
NGKEMLHH_01638	1232453.BAIF02000089_gene2922	6.82e-117	354.0	COG4974@1|root,COG4974@2|Bacteria,1UMMQ@1239|Firmicutes,25GMC@186801|Clostridia	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
NGKEMLHH_01639	457412.RSAG_00491	1.01e-124	355.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,3WH35@541000|Ruminococcaceae	186801|Clostridia	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1768,Macro
NGKEMLHH_01640	457412.RSAG_00490	3.26e-130	369.0	COG2755@1|root,COG2755@2|Bacteria,1V18W@1239|Firmicutes,24DIM@186801|Clostridia,3WP3Z@541000|Ruminococcaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NGKEMLHH_01641	411469.EUBHAL_00468	1.76e-11	65.5	COG5464@1|root,COG5464@2|Bacteria,1UK6V@1239|Firmicutes,25FNJ@186801|Clostridia,25ZUC@186806|Eubacteriaceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NGKEMLHH_01643	1121115.AXVN01000007_gene3554	0.0	1555.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
NGKEMLHH_01644	1121115.AXVN01000007_gene3553	1.73e-89	265.0	28XQJ@1|root,2ZJM8@2|Bacteria,1V2X9@1239|Firmicutes,24NE5@186801|Clostridia	186801|Clostridia	S	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
NGKEMLHH_01645	500632.CLONEX_00708	2.66e-122	351.0	COG4725@1|root,COG4725@2|Bacteria,1TSJV@1239|Firmicutes,248X5@186801|Clostridia	186801|Clostridia	KT	Belongs to the MT-A70-like family	-	-	-	-	-	-	-	-	-	-	-	-	MT-A70
NGKEMLHH_01646	411459.RUMOBE_03135	8.32e-50	165.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,3XZ1D@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NGKEMLHH_01647	411471.SUBVAR_07362	1.76e-145	416.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,3WHYW@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NGKEMLHH_01648	411459.RUMOBE_03138	6.42e-247	692.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSBI@1239|Firmicutes,24E47@186801|Clostridia,3XZZ0@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
NGKEMLHH_01649	457412.RSAG_02930	0.0	1320.0	COG0642@1|root,COG0834@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,3WSS0@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,HATPase_c,HisKA,Response_reg,SBP_bac_3,dCache_1
NGKEMLHH_01650	457412.RSAG_02931	0.0	1272.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3WGH5@541000|Ruminococcaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
NGKEMLHH_01651	457412.RSAG_02415	1.12e-265	729.0	COG4214@1|root,COG4214@2|Bacteria,1VU1F@1239|Firmicutes,24XS9@186801|Clostridia,3WGFE@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	xylH	-	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
NGKEMLHH_01652	1121115.AXVN01000015_gene3726	0.0	989.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3Y18A@572511|Blautia	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
NGKEMLHH_01653	1121115.AXVN01000015_gene3725	5.65e-255	699.0	COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3Y2A7@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10546	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	Peripla_BP_4
NGKEMLHH_01654	1121115.AXVN01000015_gene3724	3.68e-256	703.0	COG4213@1|root,COG4213@2|Bacteria,1UNTA@1239|Firmicutes	1239|Firmicutes	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NGKEMLHH_01655	1121115.AXVN01000015_gene3723	0.0	1025.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,24AFC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NGKEMLHH_01656	457412.RSAG_02410	0.0	922.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia,3WHGB@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NGKEMLHH_01657	1121115.AXVN01000015_gene3721	2.68e-229	633.0	COG1879@1|root,COG1879@2|Bacteria,1V3FA@1239|Firmicutes,24G5Q@186801|Clostridia,3Y1NU@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NGKEMLHH_01658	1121115.AXVN01000134_gene413	2.13e-281	770.0	COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,3XYM0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NGKEMLHH_01659	1121115.AXVN01000134_gene412	7.38e-295	803.0	COG0078@1|root,COG0078@2|Bacteria,1TNY4@1239|Firmicutes,249P4@186801|Clostridia,3XYQV@572511|Blautia	186801|Clostridia	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	ygeW	-	-	-	-	-	-	-	-	-	-	-	OTCace,OTCace_N
NGKEMLHH_01660	1121115.AXVN01000134_gene411	2.38e-224	618.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,3XZFB@572511|Blautia	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NGKEMLHH_01661	1121115.AXVN01000008_gene2712	8.49e-128	365.0	COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,249YQ@186801|Clostridia,3XZCZ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
NGKEMLHH_01662	457412.RSAG_02573	2.03e-224	619.0	COG3191@1|root,COG3191@2|Bacteria,1TP60@1239|Firmicutes,24AVR@186801|Clostridia,3WGD5@541000|Ruminococcaceae	186801|Clostridia	EQ	peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
NGKEMLHH_01663	1121115.AXVN01000008_gene2715	1.33e-275	754.0	COG0738@1|root,COG0738@2|Bacteria,1TQPE@1239|Firmicutes,24AF8@186801|Clostridia,3XYNH@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NGKEMLHH_01665	457412.RSAG_02776	0.0	1210.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQRN@1239|Firmicutes,247QG@186801|Clostridia,3WH1R@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
NGKEMLHH_01666	457412.RSAG_02777	0.0	1060.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia,3WJUQ@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
NGKEMLHH_01667	622312.ROSEINA2194_01819	8.19e-47	157.0	COG1961@1|root,COG1961@2|Bacteria,1VC71@1239|Firmicutes,24QC3@186801|Clostridia	186801|Clostridia	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01668	742733.HMPREF9469_05569	1.17e-177	505.0	COG0582@1|root,COG0582@2|Bacteria,1TXU3@1239|Firmicutes,24C0Y@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NGKEMLHH_01669	742733.HMPREF9469_05568	1.26e-207	598.0	COG0582@1|root,COG0582@2|Bacteria,1TQQ1@1239|Firmicutes,24BI9@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
NGKEMLHH_01670	1121115.AXVN01000032_gene385	0.0	1664.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3XYXU@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
NGKEMLHH_01671	457412.RSAG_00178	2.23e-202	561.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WGRJ@541000|Ruminococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
NGKEMLHH_01672	428125.CLOLEP_02072	1.6e-25	101.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,3WKQY@541000|Ruminococcaceae	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
NGKEMLHH_01673	1121334.KB911066_gene907	6.41e-28	109.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3WH9Z@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
NGKEMLHH_01675	511680.BUTYVIB_00391	3.75e-303	827.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,24A83@186801|Clostridia,4BYZ3@830|Butyrivibrio	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
NGKEMLHH_01677	1121115.AXVN01000036_gene2428	9.45e-261	713.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3XYHE@572511|Blautia	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NGKEMLHH_01678	457412.RSAG_02340	3.75e-109	315.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,3WJEQ@541000|Ruminococcaceae	186801|Clostridia	S	small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
NGKEMLHH_01679	546271.Selsp_0701	8.15e-130	384.0	2DB9A@1|root,2Z7VI@2|Bacteria,1TT2W@1239|Firmicutes	1239|Firmicutes	S	Adenine-specific methyltransferase EcoRI	-	-	-	-	-	-	-	-	-	-	-	-	EcoRI_methylase
NGKEMLHH_01680	1095743.HMPREF1054_1933	4.83e-38	138.0	2DB9A@1|root,2Z7VI@2|Bacteria,1QI03@1224|Proteobacteria,1TFSG@1236|Gammaproteobacteria,1YA2V@135625|Pasteurellales	135625|Pasteurellales	S	Adenine-specific methyltransferase EcoRI	-	-	-	-	-	-	-	-	-	-	-	-	EcoRI_methylase
NGKEMLHH_01681	457415.HMPREF1006_02508	3.42e-229	635.0	COG1403@1|root,COG1479@1|root,COG1403@2|Bacteria,COG1479@2|Bacteria,3TBZ6@508458|Synergistetes	508458|Synergistetes	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF262,HNH
NGKEMLHH_01685	457412.RSAG_00886	2.49e-277	758.0	COG1820@1|root,COG1820@2|Bacteria,1UK3V@1239|Firmicutes,25FIQ@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation	iadA	-	-	ko:K01305	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Amidohydro_1
NGKEMLHH_01686	457412.RSAG_00885	9.08e-202	559.0	COG1737@1|root,COG1737@2|Bacteria,1VBUB@1239|Firmicutes,24MTV@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NGKEMLHH_01687	457412.RSAG_00884	1.1e-50	160.0	2E714@1|root,331JV@2|Bacteria,1VQIV@1239|Firmicutes,251NJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01688	411474.COPEUT_00022	2.04e-224	631.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
NGKEMLHH_01689	411461.DORFOR_01988	5.94e-70	212.0	2C5R4@1|root,2ZRGD@2|Bacteria,1V4WH@1239|Firmicutes,24HA6@186801|Clostridia,27X07@189330|Dorea	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NGKEMLHH_01690	585394.RHOM_00290	2.38e-69	210.0	COG1476@1|root,COG1476@2|Bacteria,1VDGB@1239|Firmicutes,24PE2@186801|Clostridia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_01691	585394.RHOM_00295	4.89e-301	821.0	COG2312@1|root,COG2312@2|Bacteria,1V2ED@1239|Firmicutes,24BHP@186801|Clostridia	186801|Clostridia	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
NGKEMLHH_01692	457412.RSAG_02637	0.0	1041.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3WGA1@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
NGKEMLHH_01693	1121115.AXVN01000023_gene1809	1.1e-258	709.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,3XZ13@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NGKEMLHH_01694	1121115.AXVN01000023_gene1808	0.0	890.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZ7Q@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_01696	1121115.AXVN01000023_gene1806	2.48e-254	697.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia,3XZVW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01697	1121115.AXVN01000023_gene1805	1.2e-171	478.0	COG1180@1|root,COG1180@2|Bacteria,1V1GP@1239|Firmicutes,24G76@186801|Clostridia,3XZK7@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NGKEMLHH_01698	1121115.AXVN01000023_gene1804	8.07e-198	561.0	COG3584@1|root,COG3883@1|root,COG3584@2|Bacteria,COG3883@2|Bacteria,1UI15@1239|Firmicutes,25EA3@186801|Clostridia,3XZ75@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	-
NGKEMLHH_01699	1121115.AXVN01000023_gene1803	5.64e-59	182.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,3Y05I@572511|Blautia	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
NGKEMLHH_01700	1121115.AXVN01000023_gene1802	2.58e-255	701.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3XZRM@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NGKEMLHH_01701	1121115.AXVN01000023_gene1801	5.33e-304	829.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3XZGS@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NGKEMLHH_01702	457412.RSAG_02647	0.0	923.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,3WGQ1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NGKEMLHH_01703	585394.RHOM_04550	6.19e-145	417.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24XW6@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NGKEMLHH_01704	1203606.HMPREF1526_01164	1.74e-174	491.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,24A6G@186801|Clostridia,36G1X@31979|Clostridiaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
NGKEMLHH_01706	457412.RSAG_01875	5.28e-236	648.0	COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,25CN5@186801|Clostridia	186801|Clostridia	I	Diacylglycerol kinase catalytic domain	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
NGKEMLHH_01707	622312.ROSEINA2194_03936	1.36e-52	181.0	COG3501@1|root,COG3501@2|Bacteria,1V043@1239|Firmicutes,248CZ@186801|Clostridia	186801|Clostridia	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
NGKEMLHH_01709	1235835.C814_00901	1e-44	153.0	2E4BD@1|root,32Z71@2|Bacteria,1VFIN@1239|Firmicutes,24C7W@186801|Clostridia,3WR50@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01710	1345695.CLSA_c08330	1.47e-08	58.2	29YA9@1|root,30K4C@2|Bacteria,1UWG0@1239|Firmicutes,24Z3Q@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4280)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4280
NGKEMLHH_01713	658086.HMPREF0994_01759	0.0	924.0	28JMD@1|root,2Z9DX@2|Bacteria,1UM68@1239|Firmicutes,24CYH@186801|Clostridia,27RFX@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	csh	-	-	ko:K19114	-	-	-	-	ko00000,ko02048	-	-	-	-
NGKEMLHH_01714	658086.HMPREF0994_01758	3.51e-223	615.0	COG3649@1|root,COG3649@2|Bacteria,1UKQK@1239|Firmicutes,24C9C@186801|Clostridia,27QS5@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Pfam:DUF694	-	-	-	ko:K19115	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas7
NGKEMLHH_01715	658086.HMPREF0994_01757	1.76e-27	105.0	28NN3@1|root,2ZBNI@2|Bacteria,1V27F@1239|Firmicutes,24G81@186801|Clostridia,27RQG@186928|unclassified Lachnospiraceae	186801|Clostridia	S	CRISPR-associated protein Cas5	cas5h	-	-	ko:K19116	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
NGKEMLHH_01716	658086.HMPREF0994_01757	2.21e-94	278.0	28NN3@1|root,2ZBNI@2|Bacteria,1V27F@1239|Firmicutes,24G81@186801|Clostridia,27RQG@186928|unclassified Lachnospiraceae	186801|Clostridia	S	CRISPR-associated protein Cas5	cas5h	-	-	ko:K19116	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
NGKEMLHH_01717	457412.RSAG_01256	6.31e-159	446.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WG7X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_01718	1123263.AUKY01000073_gene2042	2.37e-134	394.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,3VNR9@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_01719	1121115.AXVN01000006_gene2110	4.03e-186	525.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,3XZRA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
NGKEMLHH_01720	457412.RSAG_00727	1.76e-39	131.0	COG3655@1|root,COG3655@2|Bacteria,1TU95@1239|Firmicutes,25804@186801|Clostridia,3WQZ7@541000|Ruminococcaceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
NGKEMLHH_01721	457412.RSAG_00726	9.52e-56	173.0	2C1AP@1|root,33ZCD@2|Bacteria,1VYDT@1239|Firmicutes,2529X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01722	1121115.AXVN01000006_gene2107	4.98e-308	840.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3XZMY@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
NGKEMLHH_01723	457412.RSAG_02186	9.59e-287	784.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3WGSI@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
NGKEMLHH_01724	1121115.AXVN01000024_gene291	1.86e-213	589.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,3XZI8@572511|Blautia	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
NGKEMLHH_01725	1121115.AXVN01000024_gene292	4.94e-288	786.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3XYZW@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NGKEMLHH_01726	1121115.AXVN01000006_gene2182	9e-162	463.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,3XYTG@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NGKEMLHH_01727	1121115.AXVN01000006_gene2183	4.59e-240	659.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,3XZB3@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NGKEMLHH_01728	1121115.AXVN01000006_gene2184	5.6e-159	446.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,3XZGI@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
NGKEMLHH_01729	1121115.AXVN01000006_gene2185	3.93e-205	568.0	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,24HI3@186801|Clostridia,3Y05C@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	spoIIGA	-	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
NGKEMLHH_01730	877420.ATVW01000002_gene1188	4.38e-72	229.0	COG1835@1|root,COG1835@2|Bacteria,1UY2A@1239|Firmicutes,24D38@186801|Clostridia,27IZK@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NGKEMLHH_01731	553184.ATORI0001_1372	8.56e-66	203.0	COG1476@1|root,COG2002@1|root,COG1476@2|Bacteria,COG2002@2|Bacteria,2H8HI@201174|Actinobacteria,4CW84@84998|Coriobacteriia	84998|Coriobacteriia	K	AbrB family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_01732	1280698.AUJS01000036_gene57	2.18e-101	298.0	COG1476@1|root,COG1476@2|Bacteria,1UUSK@1239|Firmicutes,247YW@186801|Clostridia,27VTS@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Zn_ribbon_2
NGKEMLHH_01733	457412.RSAG_01324	4.97e-56	185.0	COG0675@1|root,COG0675@2|Bacteria,1TQAH@1239|Firmicutes,24EGY@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
NGKEMLHH_01734	1121115.AXVN01000004_gene1986	3.16e-47	158.0	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,3Y03Y@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	araC_2	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
NGKEMLHH_01735	457412.RSAG_00418	1.26e-146	416.0	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,3WGYB@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	araC_2	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
NGKEMLHH_01736	457412.RSAG_00023	1.26e-286	783.0	COG0614@1|root,COG0614@2|Bacteria,1TQ4U@1239|Firmicutes,249I2@186801|Clostridia,3WHGS@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
NGKEMLHH_01737	1121115.AXVN01000002_gene1388	2.56e-227	628.0	COG0609@1|root,COG0609@2|Bacteria,1TQXW@1239|Firmicutes,249TJ@186801|Clostridia,3Y151@572511|Blautia	186801|Clostridia	P	FecCD transport family	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NGKEMLHH_01738	457412.RSAG_00025	3.81e-275	753.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,3WHJY@541000|Ruminococcaceae	186801|Clostridia	HP	ATPases associated with a variety of cellular activities	fepC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,zf-like
NGKEMLHH_01739	457412.RSAG_00746	2.79e-299	825.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3WGE5@541000|Ruminococcaceae	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
NGKEMLHH_01740	457412.RSAG_00747	2.63e-130	370.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia,3WM72@541000|Ruminococcaceae	186801|Clostridia	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
NGKEMLHH_01741	1121115.AXVN01000006_gene2128	3.38e-251	689.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3XZ9Q@572511|Blautia	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
NGKEMLHH_01742	1121115.AXVN01000041_gene2584	2.26e-46	149.0	COG1925@1|root,COG1925@2|Bacteria,1VEJ5@1239|Firmicutes,24R2F@186801|Clostridia,3Y0M0@572511|Blautia	186801|Clostridia	G	phosphocarrier protein HPr	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NGKEMLHH_01743	457412.RSAG_01358	0.0	939.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WH6T@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
NGKEMLHH_01744	1121115.AXVN01000041_gene2582	0.0	1384.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3XZ1H@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	glnA1	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
NGKEMLHH_01745	457412.RSAG_01360	0.0	1109.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,3WH0N@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the P(II) protein family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
NGKEMLHH_01746	1121115.AXVN01000041_gene2580	1.33e-27	100.0	2FHG3@1|root,349A5@2|Bacteria,1W08H@1239|Firmicutes,2530C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01748	457412.RSAG_04649	1.4e-69	210.0	2EQXM@1|root,33IHB@2|Bacteria,1VXES@1239|Firmicutes,251R2@186801|Clostridia	186801|Clostridia	S	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
NGKEMLHH_01749	457412.RSAG_01363	1.1e-80	239.0	2F0TM@1|root,33TVK@2|Bacteria,1VV0H@1239|Firmicutes,250FJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01750	457412.RSAG_01364	2.38e-109	317.0	COG4512@1|root,COG4512@2|Bacteria,1V7Q2@1239|Firmicutes,24KC5@186801|Clostridia	186801|Clostridia	KOT	Accessory gene regulator B	-	-	-	-	-	-	-	-	-	-	-	-	AgrB
NGKEMLHH_01751	1121115.AXVN01000041_gene2577	7.08e-26	95.5	2CCVY@1|root,33DUW@2|Bacteria,1VP6Q@1239|Firmicutes,24TVP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01752	1235802.C823_04404	9.72e-54	170.0	COG1396@1|root,COG1396@2|Bacteria,1VGTD@1239|Firmicutes,25P5X@186801|Clostridia,25ZCJ@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_01753	1121115.AXVN01000041_gene2576	8.69e-167	466.0	COG3279@1|root,COG3279@2|Bacteria,1V140@1239|Firmicutes,24C89@186801|Clostridia,3Y0PE@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
NGKEMLHH_01754	457412.RSAG_01368	2.73e-301	823.0	COG0642@1|root,COG0642@2|Bacteria,1UICJ@1239|Firmicutes,24NYC@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NGKEMLHH_01755	457412.RSAG_01370	4.13e-104	301.0	COG1853@1|root,COG1853@2|Bacteria,1UYJS@1239|Firmicutes,24DWF@186801|Clostridia,3WRH6@541000|Ruminococcaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NGKEMLHH_01756	1121115.AXVN01000041_gene2574	3.54e-148	417.0	COG2860@1|root,COG2860@2|Bacteria,1UH1K@1239|Firmicutes,24HHG@186801|Clostridia,3XYJI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yicG	-	-	-	-	-	-	-	-	-	-	-	UPF0126
NGKEMLHH_01757	457412.RSAG_01324	2.82e-116	343.0	COG0675@1|root,COG0675@2|Bacteria,1TQAH@1239|Firmicutes,24EGY@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
NGKEMLHH_01759	457412.RSAG_03312	2.04e-212	598.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,3WHYT@541000|Ruminococcaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
NGKEMLHH_01760	411459.RUMOBE_02375	7.8e-42	137.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,3Y0P0@572511|Blautia	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
NGKEMLHH_01761	457412.RSAG_03310	6.36e-48	156.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,3WKGV@541000|Ruminococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
NGKEMLHH_01762	411459.RUMOBE_02377	5.6e-21	82.8	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,3Y0UU@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
NGKEMLHH_01763	1121115.AXVN01000073_gene2008	1.13e-82	256.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3XYIB@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NGKEMLHH_01764	457412.RSAG_03091	3.55e-43	141.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes,25N7Y@186801|Clostridia,3WM7P@541000|Ruminococcaceae	186801|Clostridia	U	Preprotein translocase SecG subunit	-	-	-	-	-	-	-	-	-	-	-	-	SecG
NGKEMLHH_01765	457412.RSAG_03090	0.0	1460.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3WGHJ@541000|Ruminococcaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
NGKEMLHH_01766	457412.RSAG_03089	1.34e-104	302.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3WIZR@541000|Ruminococcaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
NGKEMLHH_01768	457412.RSAG_02566	2.29e-130	370.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V5G6@1239|Firmicutes,24928@186801|Clostridia,3WKCT@541000|Ruminococcaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
NGKEMLHH_01769	457412.RSAG_02565	7.77e-301	819.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3WGQA@541000|Ruminococcaceae	186801|Clostridia	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NGKEMLHH_01770	1121115.AXVN01000107_gene613	1.85e-130	371.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia,3Y0SC@572511|Blautia	186801|Clostridia	S	Thiamine-precursor transporter protein (ThiW)	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
NGKEMLHH_01771	1121115.AXVN01000107_gene612	1.58e-144	409.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,3XZZP@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
NGKEMLHH_01772	457412.RSAG_01700	3.89e-290	796.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WH4B@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_01773	457412.RSAG_03441	1.03e-72	223.0	COG2207@1|root,COG2207@2|Bacteria,1U23Q@1239|Firmicutes,25BMJ@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NGKEMLHH_01774	1121115.AXVN01000161_gene1326	3.47e-154	432.0	COG2755@1|root,COG2755@2|Bacteria,1V49F@1239|Firmicutes,24D1K@186801|Clostridia,3Y0I8@572511|Blautia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NGKEMLHH_01775	1121115.AXVN01000161_gene1325	3.25e-145	410.0	COG0765@1|root,COG0765@2|Bacteria,1TRU3@1239|Firmicutes,249IY@186801|Clostridia	186801|Clostridia	P	ABC transporter, permease protein	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
NGKEMLHH_01776	1121115.AXVN01000161_gene1324	1.05e-153	432.0	COG0765@1|root,COG0765@2|Bacteria,1TR7R@1239|Firmicutes,24823@186801|Clostridia	186801|Clostridia	P	acid ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
NGKEMLHH_01777	1121115.AXVN01000161_gene1323	1.95e-171	479.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia	186801|Clostridia	E	abc transporter atp-binding protein	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
NGKEMLHH_01778	1087481.AGFX01000030_gene413	1.8e-23	97.8	COG2320@1|root,COG2320@2|Bacteria,1TZ5E@1239|Firmicutes,4I8CI@91061|Bacilli,26ZKB@186822|Paenibacillaceae	91061|Bacilli	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
NGKEMLHH_01779	33035.JPJF01000086_gene919	1.15e-85	253.0	COG1396@1|root,COG1396@2|Bacteria,1VHJY@1239|Firmicutes,24S29@186801|Clostridia,3Y2CT@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_01780	33035.JPJF01000086_gene918	5.52e-71	213.0	2DKVE@1|root,30GA7@2|Bacteria,1V61Z@1239|Firmicutes,24HJK@186801|Clostridia,3Y08A@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01781	411461.DORFOR_00514	1.31e-166	469.0	28KEB@1|root,2ZA0K@2|Bacteria,1V14E@1239|Firmicutes,24UU8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01783	457412.RSAG_01679	4.19e-202	559.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia,3WHMV@541000|Ruminococcaceae	186801|Clostridia	L	NADH pyrophosphatase zinc ribbon domain	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
NGKEMLHH_01784	1121115.AXVN01000014_gene1239	1.44e-228	634.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,3XYJ1@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
NGKEMLHH_01785	457412.RSAG_01681	1.34e-108	312.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3WHNP@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
NGKEMLHH_01786	457412.RSAG_01682	3.04e-105	304.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3WHNP@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
NGKEMLHH_01787	1002367.HMPREF0673_00070	1.3e-129	409.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,4NEQG@976|Bacteroidetes,2FMSW@200643|Bacteroidia	976|Bacteroidetes	L	Helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,SNF2_N
NGKEMLHH_01788	1122971.BAME01000105_gene5942	0.0	1268.0	COG0480@1|root,COG0480@2|Bacteria,4NGRM@976|Bacteroidetes,2FP30@200643|Bacteroidia,22XI9@171551|Porphyromonadaceae	976|Bacteroidetes	J	Elongation Factor G, domain II	tetP	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
NGKEMLHH_01789	699246.HMPREF0868_1330	2.75e-24	94.4	2DM0E@1|root,315BV@2|Bacteria,1V7YE@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MobC
NGKEMLHH_01790	1384066.JAGT01000001_gene189	2.55e-255	705.0	COG0635@1|root,COG0635@2|Bacteria,1TUUY@1239|Firmicutes,2490N@186801|Clostridia,3WNY0@541000|Ruminococcaceae	186801|Clostridia	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NGKEMLHH_01791	1408321.JNJD01000008_gene2089	1.73e-194	541.0	COG0535@1|root,COG0535@2|Bacteria,1TSAT@1239|Firmicutes,24A6W@186801|Clostridia,27J66@186928|unclassified Lachnospiraceae	186801|Clostridia	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
NGKEMLHH_01792	1121115.AXVN01000002_gene1396	0.0	1011.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NGKEMLHH_01794	1121115.AXVN01000002_gene1395	1.29e-28	110.0	COG2931@1|root,COG2931@2|Bacteria,1TSGB@1239|Firmicutes,247TS@186801|Clostridia,3Y1XR@572511|Blautia	186801|Clostridia	Q	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
NGKEMLHH_01795	1121115.AXVN01000071_gene3943	0.0	1122.0	COG3064@1|root,COG5492@1|root,COG3064@2|Bacteria,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,3Y1MU@572511|Blautia	186801|Clostridia	N	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,LRR_5,N_methyl,fn3
NGKEMLHH_01796	1121115.AXVN01000071_gene3941	0.0	1170.0	COG1657@1|root,COG5492@1|root,COG1657@2|Bacteria,COG5492@2|Bacteria,1UZVS@1239|Firmicutes,24DV2@186801|Clostridia,3Y094@572511|Blautia	186801|Clostridia	IN	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Prenyltrans,SLH,SQHop_cyclase_C
NGKEMLHH_01797	1121115.AXVN01000071_gene3940	3.32e-236	657.0	COG2247@1|root,COG2247@2|Bacteria,1UNK1@1239|Firmicutes,25H40@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
NGKEMLHH_01798	1121115.AXVN01000071_gene3939	5.48e-214	593.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,3XZVA@572511|Blautia	186801|Clostridia	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
NGKEMLHH_01799	1121115.AXVN01000071_gene3938	0.0	1014.0	COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,3XYUV@572511|Blautia	186801|Clostridia	G	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS,ECF_trnsprt
NGKEMLHH_01800	1121115.AXVN01000071_gene3937	7.84e-185	517.0	COG4720@1|root,COG4720@2|Bacteria,1V2DR@1239|Firmicutes,249XR@186801|Clostridia,3XZUX@572511|Blautia	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF-ribofla_trS,ECF_trnsprt
NGKEMLHH_01801	1121115.AXVN01000071_gene3936	0.0	1129.0	COG5492@1|root,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,3Y0E9@572511|Blautia	186801|Clostridia	N	endoglucanase-related protein, glucosyl hydrolase family 9 protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF11,DUF4430,Flg_new
NGKEMLHH_01802	411459.RUMOBE_03452	8.16e-130	387.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,3Y0RN@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
NGKEMLHH_01803	1121115.AXVN01000038_gene3315	1.94e-60	186.0	COG1669@1|root,COG1669@2|Bacteria,1VEWI@1239|Firmicutes,25DNH@186801|Clostridia,3Y1WZ@572511|Blautia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
NGKEMLHH_01804	457412.RSAG_02896	8.67e-101	300.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,3WH0R@541000|Ruminococcaceae	186801|Clostridia	P	nlpA lipoprotein	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
NGKEMLHH_01805	457412.RSAG_02899	8.54e-37	137.0	COG3210@1|root,COG4886@1|root,COG3210@2|Bacteria,COG4886@2|Bacteria,1V6R1@1239|Firmicutes,24K56@186801|Clostridia	186801|Clostridia	U	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
NGKEMLHH_01806	457412.RSAG_02899	4.49e-23	101.0	COG3210@1|root,COG4886@1|root,COG3210@2|Bacteria,COG4886@2|Bacteria,1V6R1@1239|Firmicutes,24K56@186801|Clostridia	186801|Clostridia	U	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
NGKEMLHH_01810	1121115.AXVN01000004_gene1960	6.85e-266	733.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3Y16V@572511|Blautia	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
NGKEMLHH_01811	457412.RSAG_00393	9.23e-270	737.0	COG1996@1|root,COG1996@2|Bacteria,1UI9I@1239|Firmicutes,248XK@186801|Clostridia,3WHNV@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01812	1121115.AXVN01000004_gene1958	2.35e-182	509.0	COG1512@1|root,COG1512@2|Bacteria,1V2US@1239|Firmicutes,257P6@186801|Clostridia,3Y1PM@572511|Blautia	186801|Clostridia	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
NGKEMLHH_01813	457412.RSAG_02330	1.58e-174	496.0	COG4585@1|root,COG4585@2|Bacteria,1V4GJ@1239|Firmicutes,24M3N@186801|Clostridia,3WJCM@541000|Ruminococcaceae	186801|Clostridia	T	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01814	457412.RSAG_02331	3.44e-146	412.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24E7M@186801|Clostridia,3WJQ7@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07694	ko02020,map02020	M00480	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
NGKEMLHH_01815	457412.RSAG_02332	7.32e-216	595.0	2BB5X@1|root,324NG@2|Bacteria,1V7KI@1239|Firmicutes,24MCT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01817	457412.RSAG_00078	5.32e-261	726.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,3WH19@541000|Ruminococcaceae	186801|Clostridia	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
NGKEMLHH_01818	457412.RSAG_00077	0.0	1124.0	COG5492@1|root,COG5492@2|Bacteria,1UK32@1239|Firmicutes,25FHP@186801|Clostridia	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FIVAR,PBP-Tp47_a,PBP-Tp47_c
NGKEMLHH_01819	457412.RSAG_01330	2.5e-59	183.0	COG1061@1|root,COG1061@2|Bacteria	2|Bacteria	L	Type III restriction enzyme res subunit	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	AAA_11,AAA_12,AAA_19,DUF2075,DUF3883,NERD,PLDc_2,ResIII,UvrD_C
NGKEMLHH_01820	457412.RSAG_01331	0.0	2010.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,3WHD8@541000|Ruminococcaceae	186801|Clostridia	L	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
NGKEMLHH_01821	411469.EUBHAL_01634	9.57e-241	662.0	COG1073@1|root,COG1073@2|Bacteria,1TPW7@1239|Firmicutes,24A5B@186801|Clostridia,25VKG@186806|Eubacteriaceae	186801|Clostridia	S	Dienelactone hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,DLH,Peptidase_S15
NGKEMLHH_01822	411469.EUBHAL_01635	1.36e-137	389.0	COG0110@1|root,COG0110@2|Bacteria,1TSQQ@1239|Firmicutes,24B8G@186801|Clostridia,25W2V@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial transferase hexapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
NGKEMLHH_01823	1410674.JNKU01000036_gene435	4.29e-99	290.0	COG0655@1|root,COG0655@2|Bacteria,1V26K@1239|Firmicutes	1239|Firmicutes	S	Nadph-dependent fmn reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NGKEMLHH_01825	1140001.I571_02512	1.3e-48	157.0	COG1359@1|root,COG1359@2|Bacteria,1V8JS@1239|Firmicutes,4HKAP@91061|Bacilli,4B3DQ@81852|Enterococcaceae	91061|Bacilli	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
NGKEMLHH_01826	457412.RSAG_01593	3.18e-24	92.8	2C9RV@1|root,32TR5@2|Bacteria,1VDVS@1239|Firmicutes,25AYH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01827	1121115.AXVN01000017_gene266	3.99e-166	464.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3Y11K@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_01828	457412.RSAG_00251	3.14e-294	803.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,249X1@186801|Clostridia,3WJCU@541000|Ruminococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NGKEMLHH_01830	1235802.C823_00083	4.65e-23	97.4	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,25V9R@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NGKEMLHH_01831	457412.RSAG_01536	1.54e-268	738.0	COG2207@1|root,COG2207@2|Bacteria,1TQD7@1239|Firmicutes,249SA@186801|Clostridia,3WP6K@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NGKEMLHH_01832	457412.RSAG_01309	7.01e-217	599.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia,3WI18@541000|Ruminococcaceae	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NGKEMLHH_01833	457412.RSAG_01310	1.25e-201	557.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,25B6S@186801|Clostridia,3WKHA@541000|Ruminococcaceae	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NGKEMLHH_01834	457412.RSAG_01311	4.96e-308	839.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,3WH7R@541000|Ruminococcaceae	186801|Clostridia	E	M18 family aminopeptidase	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
NGKEMLHH_01835	470145.BACCOP_01692	4.98e-68	206.0	2DFXB@1|root,2ZTJS@2|Bacteria,4PN1F@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2958)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2958
NGKEMLHH_01836	470145.BACCOP_01691	2.25e-47	153.0	2A85Z@1|root,30X6T@2|Bacteria,4PAJF@976|Bacteroidetes,2FUX2@200643|Bacteroidia,4AS6Z@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01838	547042.BACCOPRO_02443	9.01e-162	466.0	COG3391@1|root,COG3391@2|Bacteria,4P67C@976|Bacteroidetes,2FV6U@200643|Bacteroidia,4ASJS@815|Bacteroidaceae	976|Bacteroidetes	S	6-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128
NGKEMLHH_01839	1121115.AXVN01000072_gene3910	1.86e-86	261.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia,3XYQG@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
NGKEMLHH_01840	457412.RSAG_02113	0.0	909.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,3WRHZ@541000|Ruminococcaceae	186801|Clostridia	M	CoA-binding domain	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
NGKEMLHH_01841	457412.RSAG_02112	5.49e-272	752.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,3WGW9@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
NGKEMLHH_01842	1121115.AXVN01000072_gene3907	5.28e-237	650.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia,3XZN2@572511|Blautia	186801|Clostridia	S	LPS side chain defect rhamnosyl transferase	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
NGKEMLHH_01843	1121115.AXVN01000072_gene3906	0.0	875.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3XZRU@572511|Blautia	186801|Clostridia	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NGKEMLHH_01844	1121115.AXVN01000063_gene700	0.0	907.0	COG1219@1|root,COG1219@2|Bacteria,1TPDI@1239|Firmicutes,24AEG@186801|Clostridia,3XYQ7@572511|Blautia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX_1	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
NGKEMLHH_01845	1121115.AXVN01000063_gene701	5.57e-100	294.0	2DR5I@1|root,33A9E@2|Bacteria,1VM5P@1239|Firmicutes,24JQJ@186801|Clostridia,3Y0KF@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
NGKEMLHH_01846	1121115.AXVN01000063_gene702	0.0	889.0	COG4886@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5492@2|Bacteria,1VRK1@1239|Firmicutes,25KN7@186801|Clostridia,3Y1XU@572511|Blautia	186801|Clostridia	N	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01847	457412.RSAG_02106	3.1e-269	737.0	COG4733@1|root,COG4733@2|Bacteria,1VDWT@1239|Firmicutes,24ZKB@186801|Clostridia,3WMCI@541000|Ruminococcaceae	186801|Clostridia	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
NGKEMLHH_01849	1121115.AXVN01000063_gene704	7.86e-268	732.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3XYS9@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
NGKEMLHH_01850	1121115.AXVN01000052_gene877	2.23e-65	199.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3Y0HD@572511|Blautia	186801|Clostridia	O	Thioredoxin-like domain	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NGKEMLHH_01851	457412.RSAG_01838	8.15e-210	580.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3WIBR@541000|Ruminococcaceae	186801|Clostridia	C	pyridine	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
NGKEMLHH_01852	1121115.AXVN01000052_gene875	2.14e-297	811.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3XYZQ@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
NGKEMLHH_01853	500632.CLONEX_02350	3.1e-71	217.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,24JUT@186801|Clostridia	186801|Clostridia	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
NGKEMLHH_01854	658086.HMPREF0994_00724	3.56e-25	97.4	2EH8D@1|root,33B07@2|Bacteria,1VMHD@1239|Firmicutes,24UVN@186801|Clostridia,27QK1@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01855	1280692.AUJL01000004_gene806	2.02e-186	537.0	COG0803@1|root,COG3443@1|root,COG0803@2|Bacteria,COG3443@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,36EYU@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
NGKEMLHH_01856	471875.RUMLAC_01412	8.06e-258	707.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WHJS@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NGKEMLHH_01857	471875.RUMLAC_01411	1.25e-58	182.0	2AQJ5@1|root,31FRY@2|Bacteria,1V6TG@1239|Firmicutes,24JD1@186801|Clostridia,3WJXJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01858	471875.RUMLAC_01410	6.71e-207	577.0	COG3598@1|root,COG3598@2|Bacteria,1UIBK@1239|Firmicutes,24K1Q@186801|Clostridia,3WGEM@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol
NGKEMLHH_01859	471875.RUMLAC_01409	4.45e-42	138.0	2CIZU@1|root,3323B@2|Bacteria,1VF1D@1239|Firmicutes,24QPV@186801|Clostridia,3WM82@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01860	471875.RUMLAC_01408	3.59e-48	153.0	2DQEK@1|root,32UNY@2|Bacteria,1VCGS@1239|Firmicutes,24MR4@186801|Clostridia,3WMND@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF5348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
NGKEMLHH_01861	1123298.KB904121_gene1917	1.58e-133	382.0	COG0582@1|root,COG0582@2|Bacteria,1UMEE@1239|Firmicutes,4ITVG@91061|Bacilli	91061|Bacilli	L	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
NGKEMLHH_01862	518637.EUBIFOR_00810	1.84e-29	105.0	2EI8P@1|root,332BW@2|Bacteria,1VFSF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01863	1123263.AUKY01000003_gene276	1.17e-48	158.0	COG1396@1|root,COG1396@2|Bacteria,1VGAT@1239|Firmicutes,3VS4H@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_01864	1235799.C818_01943	1.71e-83	266.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24B23@186801|Clostridia,27M2S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
NGKEMLHH_01865	1121115.AXVN01000005_gene2270	1.49e-222	613.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,248VU@186801|Clostridia,3XYYF@572511|Blautia	186801|Clostridia	I	Phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
NGKEMLHH_01866	457412.RSAG_02998	5.9e-137	388.0	COG1183@1|root,COG1183@2|Bacteria,1TTB7@1239|Firmicutes,24GPU@186801|Clostridia,3WH5G@541000|Ruminococcaceae	186801|Clostridia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
NGKEMLHH_01867	457412.RSAG_02999	1.69e-234	646.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,3WHJD@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
NGKEMLHH_01868	246199.CUS_7649	2.77e-08	53.1	2916G@1|root,2ZNTN@2|Bacteria,1W5P3@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
NGKEMLHH_01869	1408323.JQKK01000003_gene2624	6.46e-05	45.1	29UAT@1|root,30FM1@2|Bacteria,1UE7T@1239|Firmicutes,25J2Y@186801|Clostridia,27T5M@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
NGKEMLHH_01871	457412.RSAG_02313	0.0	1154.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
NGKEMLHH_01872	1121115.AXVN01000005_gene2235	1.29e-199	573.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia,3Y17B@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NGKEMLHH_01873	1121115.AXVN01000005_gene2235	0.0	1115.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia,3Y17B@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NGKEMLHH_01874	411459.RUMOBE_02308	1.21e-142	427.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3Y1AR@572511|Blautia	186801|Clostridia	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
NGKEMLHH_01875	457412.RSAG_00794	1.56e-50	159.0	COG3655@1|root,COG3655@2|Bacteria,1VHGA@1239|Firmicutes,24VPG@186801|Clostridia	186801|Clostridia	K	Protein of unknown function (DUF739)	-	-	-	-	-	-	-	-	-	-	-	-	DUF739
NGKEMLHH_01876	1121115.AXVN01000006_gene2172	2.05e-28	102.0	2FGK7@1|root,348FZ@2|Bacteria,1W09F@1239|Firmicutes,25375@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01877	1121115.AXVN01000006_gene2171	1.7e-59	184.0	2CJIG@1|root,32SA4@2|Bacteria,1VCKV@1239|Firmicutes,24P9C@186801|Clostridia,3Y0FM@572511|Blautia	186801|Clostridia	S	Phage holin family Hol44, in holin superfamily V	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_5_2
NGKEMLHH_01878	457412.RSAG_00790	0.0	981.0	COG3409@1|root,COG3757@1|root,COG3409@2|Bacteria,COG3757@2|Bacteria,1VDIK@1239|Firmicutes,24PGG@186801|Clostridia	186801|Clostridia	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
NGKEMLHH_01879	457412.RSAG_04757	3.53e-17	72.4	COG3546@1|root,COG3546@2|Bacteria	2|Bacteria	P	catalase activity	cotJC	-	-	ko:K06334,ko:K07217	-	-	-	-	ko00000	-	-	-	Mn_catalase
NGKEMLHH_01880	1121115.AXVN01000006_gene2169	1.35e-64	196.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia,3Y0NH@572511|Blautia	186801|Clostridia	S	COG NOG18028 non supervised orthologous group	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
NGKEMLHH_01881	1121115.AXVN01000006_gene2168	1.33e-49	159.0	2EHCX@1|root,33B4S@2|Bacteria,1VKA0@1239|Firmicutes,259R7@186801|Clostridia,3Y0T8@572511|Blautia	186801|Clostridia	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA
NGKEMLHH_01882	1121115.AXVN01000032_gene379	0.0	1690.0	COG0500@1|root,COG3608@1|root,COG2226@2|Bacteria,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,3XZ0I@572511|Blautia	186801|Clostridia	Q	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA,Methyltransf_11
NGKEMLHH_01883	457412.RSAG_00183	4.31e-193	536.0	COG3773@1|root,COG3773@2|Bacteria,1VAUD@1239|Firmicutes,25B1B@186801|Clostridia	186801|Clostridia	M	Cell wall hydrolase	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2,LysM
NGKEMLHH_01884	1121115.AXVN01000009_gene1456	2.71e-235	647.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3XYNT@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NGKEMLHH_01885	457412.RSAG_00349	0.0	1513.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NGKEMLHH_01886	1121115.AXVN01000047_gene1269	1.32e-291	795.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3XYNE@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
NGKEMLHH_01887	1121115.AXVN01000047_gene1268	6.91e-174	484.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3XZ1G@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
NGKEMLHH_01888	457412.RSAG_01854	5.12e-180	503.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia,3WIZ0@541000|Ruminococcaceae	186801|Clostridia	M	Ami_2	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
NGKEMLHH_01889	1121115.AXVN01000047_gene1266	0.0	932.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
NGKEMLHH_01890	1121115.AXVN01000047_gene1265	5.98e-111	319.0	2E823@1|root,332G5@2|Bacteria,1V8A8@1239|Firmicutes,24NHT@186801|Clostridia,3Y088@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01891	1121115.AXVN01000047_gene1264	0.0	983.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
NGKEMLHH_01892	1121115.AXVN01000047_gene1263	7.18e-57	177.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3Y05R@572511|Blautia	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
NGKEMLHH_01894	1121115.AXVN01000047_gene1262	1.67e-177	495.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,2480R@186801|Clostridia,3XYZ9@572511|Blautia	186801|Clostridia	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	-	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
NGKEMLHH_01895	457412.RSAG_01860	0.0	1326.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,3WGDZ@541000|Ruminococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
NGKEMLHH_01896	1121115.AXVN01000047_gene1260	2.67e-221	610.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,3XYUB@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
NGKEMLHH_01897	457412.RSAG_01862	0.0	1004.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,3WH36@541000|Ruminococcaceae	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
NGKEMLHH_01898	1121115.AXVN01000077_gene2642	4.34e-22	87.4	2C9RV@1|root,32UDR@2|Bacteria,1VD3D@1239|Firmicutes,24NEV@186801|Clostridia,3Y1XJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01899	1121115.AXVN01000077_gene2644	1.13e-87	258.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,3Y1QS@572511|Blautia	186801|Clostridia	H	Aspartate decarboxylase	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
NGKEMLHH_01900	1121115.AXVN01000077_gene2645	2.24e-200	555.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,3Y13Y@572511|Blautia	186801|Clostridia	H	Pantoate-beta-alanine ligase	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
NGKEMLHH_01901	500632.CLONEX_04000	1.38e-115	332.0	COG3797@1|root,COG3797@2|Bacteria,1V426@1239|Firmicutes,24HUG@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
NGKEMLHH_01902	1121115.AXVN01000037_gene3257	0.0	978.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3Y1A3@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
NGKEMLHH_01903	457412.RSAG_01381	1.5e-119	342.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24JWN@186801|Clostridia,3WS23@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
NGKEMLHH_01904	1121115.AXVN01000037_gene3259	3.25e-83	249.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,258VV@186801|Clostridia,3Y0ZV@572511|Blautia	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_B
NGKEMLHH_01905	457412.RSAG_01897	2.59e-229	630.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3WHZJ@541000|Ruminococcaceae	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
NGKEMLHH_01906	457412.RSAG_01898	2.11e-217	604.0	2E2H9@1|root,32XM9@2|Bacteria,1VC5F@1239|Firmicutes,24PWJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4878,DUF5067
NGKEMLHH_01907	457412.RSAG_01899	2.67e-43	140.0	COG2155@1|root,COG2155@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF378)	yuzA	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
NGKEMLHH_01909	1121115.AXVN01000024_gene297	4.13e-166	464.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,3Y2AV@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NGKEMLHH_01910	457412.RSAG_02621	9.23e-289	792.0	COG0642@1|root,COG0642@2|Bacteria,1UKI9@1239|Firmicutes,24XZM@186801|Clostridia,3WSRW@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NGKEMLHH_01911	1121115.AXVN01000024_gene299	1.09e-225	622.0	2EZSX@1|root,33SXM@2|Bacteria,1VS9M@1239|Firmicutes,24XHD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01912	1121115.AXVN01000076_gene2627	6.5e-48	153.0	2E6AD@1|root,330Y9@2|Bacteria,1VFG8@1239|Firmicutes,24RI6@186801|Clostridia,3Y0I9@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01913	1121115.AXVN01000076_gene2628	0.0	1321.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3XYYD@572511|Blautia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NGKEMLHH_01914	457412.RSAG_02592	0.0	1560.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,3WGY1@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR-associated helicase, Cas3	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
NGKEMLHH_01915	457412.RSAG_02593	5.64e-126	361.0	28NN3@1|root,2ZBNI@2|Bacteria,1V27F@1239|Firmicutes,24G81@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein Cas5	cas5h	-	-	ko:K19116	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
NGKEMLHH_01916	1121115.AXVN01000003_gene1625	5.61e-167	467.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3XYGX@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
NGKEMLHH_01917	1121115.AXVN01000003_gene1624	2.26e-165	464.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,3XZDI@572511|Blautia	186801|Clostridia	OU	Psort location Cytoplasmic, score 8.87	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NGKEMLHH_01918	1121115.AXVN01000003_gene1623	9.66e-219	602.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,3XZM3@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
NGKEMLHH_01919	1121115.AXVN01000005_gene2265	4.66e-297	810.0	COG2873@1|root,COG2873@2|Bacteria,1TXZ1@1239|Firmicutes,248M7@186801|Clostridia,3Y1GM@572511|Blautia	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NGKEMLHH_01920	1121115.AXVN01000005_gene2266	2.45e-176	493.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,3XZ84@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
NGKEMLHH_01921	457412.RSAG_03000	1.9e-180	502.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,3WIAB@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	ssuB_2	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NGKEMLHH_01922	457412.RSAG_01877	1.14e-296	809.0	COG1277@1|root,COG1277@2|Bacteria,1UTUG@1239|Firmicutes,25EAK@186801|Clostridia,3WMG3@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
NGKEMLHH_01923	457412.RSAG_01878	1.11e-206	572.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3WHDX@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_01924	457412.RSAG_01879	8.58e-173	483.0	2DMFS@1|root,32R85@2|Bacteria,1U024@1239|Firmicutes,25MSI@186801|Clostridia,3WQUD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01925	1121115.AXVN01000016_gene3646	3.45e-245	676.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3XYK3@572511|Blautia	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
NGKEMLHH_01926	1121115.AXVN01000016_gene3645	9.77e-71	213.0	2DP3R@1|root,330E2@2|Bacteria,1VEPT@1239|Firmicutes,24QJB@186801|Clostridia,3Y0IT@572511|Blautia	186801|Clostridia	S	COG NOG16856 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
NGKEMLHH_01927	1121115.AXVN01000015_gene3701	1.08e-107	311.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,3XZXW@572511|Blautia	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
NGKEMLHH_01928	457412.RSAG_02397	6.11e-36	122.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,3WMNQ@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
NGKEMLHH_01929	1121115.AXVN01000015_gene3702	3.98e-72	217.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3Y03U@572511|Blautia	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
NGKEMLHH_01930	457412.RSAG_02399	2.09e-267	733.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,3WI31@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type branched-chain amino acid transport systems periplasmic component	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
NGKEMLHH_01931	1121115.AXVN01000015_gene3705	3.6e-189	528.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,3XYQM@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
NGKEMLHH_01932	1121115.AXVN01000015_gene3706	4.88e-232	641.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,3XYTB@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
NGKEMLHH_01933	1121115.AXVN01000015_gene3707	8.69e-180	500.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,3XZSC@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
NGKEMLHH_01934	1121115.AXVN01000015_gene3708	2.38e-160	450.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,3XZDH@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
NGKEMLHH_01935	1121115.AXVN01000015_gene3709	7.82e-147	413.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XZZT@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NGKEMLHH_01936	457412.RSAG_02403	5.62e-309	843.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,3WGT0@541000|Ruminococcaceae	186801|Clostridia	L	ATPase, AAA family	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
NGKEMLHH_01937	1121115.AXVN01000015_gene3717	2.95e-117	335.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia,3Y078@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
NGKEMLHH_01938	1121115.AXVN01000015_gene3718	1.09e-226	624.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,3XYHJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
NGKEMLHH_01939	457412.RSAG_02406	5.56e-154	434.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,3WKI6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
NGKEMLHH_01940	1121115.AXVN01000015_gene3720	3.59e-166	465.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24H9B@186801|Clostridia,3XZX4@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
NGKEMLHH_01941	1121115.AXVN01000016_gene3694	2.35e-158	445.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,3XZSK@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.99	ygaZ	-	-	-	-	-	-	-	-	-	-	-	AzlC
NGKEMLHH_01942	457412.RSAG_02357	2.47e-211	587.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NGKEMLHH_01943	1121115.AXVN01000016_gene3696	6.37e-102	294.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,25MW0@186801|Clostridia,3Y26V@572511|Blautia	186801|Clostridia	P	Ferric uptake regulator family	-	-	-	-	-	-	-	-	-	-	-	-	FUR
NGKEMLHH_01944	457412.RSAG_02355	7.65e-190	528.0	2C6CR@1|root,2Z7X4@2|Bacteria,1UY2Y@1239|Firmicutes,24EJP@186801|Clostridia,3WIK3@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_2
NGKEMLHH_01945	1121115.AXVN01000014_gene1225	3.09e-305	832.0	COG1653@1|root,COG1653@2|Bacteria,1VR2M@1239|Firmicutes,24YJT@186801|Clostridia,3Y1T3@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NGKEMLHH_01946	1121115.AXVN01000014_gene1226	2.16e-185	517.0	COG1175@1|root,COG1175@2|Bacteria,1VT09@1239|Firmicutes,24YP4@186801|Clostridia,3Y1PN@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_01947	1235792.C808_04006	1.27e-138	398.0	COG0395@1|root,COG0395@2|Bacteria,1VQXI@1239|Firmicutes,24ECS@186801|Clostridia,27N2Y@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_01948	411461.DORFOR_02945	2.67e-114	345.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,27VUE@189330|Dorea	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
NGKEMLHH_01949	742733.HMPREF9469_05719	2.99e-236	657.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,21XPZ@1506553|Lachnoclostridium	186801|Clostridia	L	COG COG3344 Retron-type reverse transcriptase	ltrA	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,Intron_maturas2,RVT_1,RVT_N
NGKEMLHH_01950	397290.C810_02840	2.84e-179	508.0	29VWE@1|root,30HEA@2|Bacteria,1UHJG@1239|Firmicutes,25QB7@186801|Clostridia,27PV5@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4297
NGKEMLHH_01951	1235792.C808_03174	8.33e-07	47.0	2BCZ7@1|root,326KC@2|Bacteria,1USGZ@1239|Firmicutes,25AH6@186801|Clostridia,27QFM@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01952	1235792.C808_03173	1.27e-276	773.0	COG1196@1|root,COG1196@2|Bacteria,1VWYZ@1239|Firmicutes,25DHD@186801|Clostridia,27KS5@186928|unclassified Lachnospiraceae	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01953	457412.RSAG_00435	1.12e-68	218.0	2EYFT@1|root,33RPP@2|Bacteria,1VSB0@1239|Firmicutes,24XZU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01954	457412.RSAG_00434	2.3e-83	246.0	COG3682@1|root,COG3682@2|Bacteria,1VEJ8@1239|Firmicutes,24R6S@186801|Clostridia,3WKEQ@541000|Ruminococcaceae	186801|Clostridia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NGKEMLHH_01955	457412.RSAG_00433	0.0	1077.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,24A30@186801|Clostridia,3WJX1@541000|Ruminococcaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
NGKEMLHH_01956	457412.RSAG_00449	0.0	1236.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,3WGJR@541000|Ruminococcaceae	186801|Clostridia	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
NGKEMLHH_01957	1121115.AXVN01000045_gene2056	0.0	1046.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,3XZ89@572511|Blautia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
NGKEMLHH_01958	1121115.AXVN01000045_gene2057	2.85e-165	464.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,3XZ8P@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
NGKEMLHH_01959	1121115.AXVN01000020_gene112	4.19e-267	736.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,3XZ5I@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NGKEMLHH_01960	1121115.AXVN01000020_gene111	3.91e-237	667.0	COG4942@1|root,COG5263@1|root,COG4942@2|Bacteria,COG5263@2|Bacteria,1VH35@1239|Firmicutes,25KD3@186801|Clostridia,3Y04J@572511|Blautia	186801|Clostridia	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Peptidase_M23
NGKEMLHH_01961	1121115.AXVN01000020_gene110	1.56e-98	286.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,3Y0GI@572511|Blautia	186801|Clostridia	S	Thioesterase-like superfamily	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
NGKEMLHH_01962	1121115.AXVN01000081_gene3045	3.63e-48	184.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3XZ6E@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NGKEMLHH_01963	478749.BRYFOR_05099	1.18e-141	411.0	COG4409@1|root,COG4409@2|Bacteria,1V5Q1@1239|Firmicutes,24FGZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130,Glyco_hydro_32N,Glyco_hydro_43
NGKEMLHH_01964	575593.HMPREF0491_01139	3.57e-44	152.0	COG0395@1|root,COG0395@2|Bacteria,1U0R6@1239|Firmicutes,248I2@186801|Clostridia,27JXE@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_01965	679200.HMPREF9333_01256	9.01e-73	223.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_01966	883113.HMPREF9708_00973	4.64e-201	561.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,4HGDC@91061|Bacilli,27E3Q@186827|Aerococcaceae	91061|Bacilli	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	nsaS	-	2.7.13.3	ko:K19081	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
NGKEMLHH_01967	908337.HMPREF9257_0389	2.01e-164	461.0	2DCPZ@1|root,2ZEW4@2|Bacteria,1V1NN@1239|Firmicutes,4HGEE@91061|Bacilli,27EMF@186827|Aerococcaceae	91061|Bacilli	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
NGKEMLHH_01968	883113.HMPREF9708_00976	5.1e-164	461.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,27DKK@186827|Aerococcaceae	91061|Bacilli	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_01969	457412.RSAG_02046	1.17e-124	355.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,3WJ0K@541000|Ruminococcaceae	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
NGKEMLHH_01970	1121115.AXVN01000094_gene757	1.26e-288	790.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3XYJC@572511|Blautia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
NGKEMLHH_01971	1121115.AXVN01000094_gene758	2.01e-133	378.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,3XYT9@572511|Blautia	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NGKEMLHH_01972	457412.RSAG_02043	6.6e-312	850.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WGYG@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
NGKEMLHH_01973	457412.RSAG_02042	0.0	1464.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3WH4M@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
NGKEMLHH_01974	457412.RSAG_02041	2.08e-139	394.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,3WH1B@541000|Ruminococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
NGKEMLHH_01975	1121115.AXVN01000094_gene762	8.15e-204	563.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3XZE9@572511|Blautia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NGKEMLHH_01976	457412.RSAG_02039	3.79e-250	687.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WG8V@541000|Ruminococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NGKEMLHH_01977	1121115.AXVN01000094_gene764	2.89e-181	505.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,3XYPD@572511|Blautia	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
NGKEMLHH_01978	1121115.AXVN01000094_gene765	3.85e-180	501.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3XYU9@572511|Blautia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
NGKEMLHH_01979	1121115.AXVN01000094_gene766	1.05e-101	294.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3XZVZ@572511|Blautia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
NGKEMLHH_01980	457412.RSAG_02035	3.13e-86	254.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
NGKEMLHH_01981	411461.DORFOR_03171	1.07e-66	203.0	COG1476@1|root,COG1476@2|Bacteria,1V4DH@1239|Firmicutes,24HSN@186801|Clostridia,27WQG@189330|Dorea	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_01982	457412.RSAG_02032	2.17e-39	130.0	COG2909@1|root,COG2909@2|Bacteria,1VGAF@1239|Firmicutes,24SMP@186801|Clostridia,3WM0N@541000|Ruminococcaceae	186801|Clostridia	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NGKEMLHH_01983	1121115.AXVN01000024_gene306	0.0	1420.0	COG0457@1|root,COG0457@2|Bacteria,1TSH7@1239|Firmicutes,248J1@186801|Clostridia,3Y14T@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01984	1121115.AXVN01000024_gene305	5.91e-75	237.0	COG5337@1|root,COG5337@2|Bacteria,1UMDN@1239|Firmicutes,25GFF@186801|Clostridia	186801|Clostridia	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
NGKEMLHH_01985	457412.RSAG_02873	5.58e-221	610.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WGUM@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
NGKEMLHH_01986	411459.RUMOBE_02843	3.06e-130	370.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3XYWU@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
NGKEMLHH_01987	1121115.AXVN01000046_gene2958	2.78e-85	251.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3XZVK@572511|Blautia	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
NGKEMLHH_01988	1121115.AXVN01000046_gene2959	2.1e-78	233.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3Y043@572511|Blautia	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
NGKEMLHH_01989	1121115.AXVN01000010_gene2761	1.77e-62	191.0	COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,24MN2@186801|Clostridia	186801|Clostridia	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
NGKEMLHH_01990	1121115.AXVN01000010_gene2762	3.91e-82	243.0	COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,24N65@186801|Clostridia	186801|Clostridia	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
NGKEMLHH_01991	457412.RSAG_01445	0.0	1151.0	COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,24D62@186801|Clostridia,3WGSE@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
NGKEMLHH_01992	903814.ELI_1009	1.19e-73	221.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24N0J@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_01993	718252.FP2_03590	1.58e-144	411.0	2EKXF@1|root,33EM0@2|Bacteria,1VRNT@1239|Firmicutes,24ER4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_01995	457412.RSAG_00909	3.68e-132	377.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NGKEMLHH_01996	457412.RSAG_00910	0.0	885.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_01997	552398.HMPREF0866_00033	1.47e-81	247.0	COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,248UQ@186801|Clostridia,3WQQT@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the D-glutamate cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1445
NGKEMLHH_01998	411461.DORFOR_00157	1.31e-78	239.0	COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,248UQ@186801|Clostridia	186801|Clostridia	S	Belongs to the D-glutamate cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1445
NGKEMLHH_02000	1121115.AXVN01000061_gene493	0.0	1827.0	COG3459@1|root,COG3459@2|Bacteria,1UYFP@1239|Firmicutes,24A8A@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
NGKEMLHH_02002	457412.RSAG_01882	0.0	1148.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WGKA@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase catalytic	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
NGKEMLHH_02004	1121115.AXVN01000131_gene736	0.0	1061.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,3Y0FH@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score 9.99	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
NGKEMLHH_02005	1121115.AXVN01000131_gene735	2.12e-176	493.0	COG2221@1|root,COG2221@2|Bacteria,1UI1A@1239|Firmicutes,25EAA@186801|Clostridia,3Y28E@572511|Blautia	186801|Clostridia	C	Nitrite and sulphite reductase 4Fe-4S domain	dsvA	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C,Fer4,Fer4_10,NIR_SIR,NIR_SIR_ferr
NGKEMLHH_02006	457412.RSAG_02311	9.91e-25	99.4	COG2221@1|root,COG2221@2|Bacteria,1UI1A@1239|Firmicutes,25EAA@186801|Clostridia,3WSRT@541000|Ruminococcaceae	186801|Clostridia	C	Nitrite/Sulfite reductase ferredoxin-like half domain	dsvA	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C,Fer4,Fer4_10,NIR_SIR,NIR_SIR_ferr
NGKEMLHH_02008	1305737.JAFX01000001_gene1392	6.25e-06	56.2	COG3391@1|root,COG3391@2|Bacteria,4NNMZ@976|Bacteroidetes	976|Bacteroidetes	S	6-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128
NGKEMLHH_02010	457412.RSAG_01693	6.88e-195	546.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,3WSRQ@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NGKEMLHH_02011	457412.RSAG_01694	7.99e-253	693.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,3WH25@541000|Ruminococcaceae	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
NGKEMLHH_02012	457412.RSAG_01696	6.48e-99	286.0	COG3543@1|root,COG3543@2|Bacteria,1VAZC@1239|Firmicutes,25DS7@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1284)	-	-	-	ko:K09706	-	-	-	-	ko00000	-	-	-	DUF1284
NGKEMLHH_02013	1121115.AXVN01000107_gene614	1.99e-145	414.0	COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,248I1@186801|Clostridia,3XYIR@572511|Blautia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NGKEMLHH_02014	1121115.AXVN01000021_gene1711	2.92e-162	454.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,3XYGU@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_02015	1121115.AXVN01000021_gene1710	4.04e-266	729.0	COG5002@1|root,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia,3XZ9P@572511|Blautia	186801|Clostridia	T	COG COG0642 Signal transduction histidine kinase	yycG_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NGKEMLHH_02016	1121115.AXVN01000021_gene1709	1.25e-284	777.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3XZ7D@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
NGKEMLHH_02017	1121115.AXVN01000021_gene1708	1.35e-300	821.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3XZ1V@572511|Blautia	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
NGKEMLHH_02018	1121115.AXVN01000021_gene1707	6.42e-112	322.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia,3Y00E@572511|Blautia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
NGKEMLHH_02019	457412.RSAG_03298	9.98e-140	394.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,3WIF0@541000|Ruminococcaceae	186801|Clostridia	S	Flavin reductase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NGKEMLHH_02020	457412.RSAG_03299	0.0	1090.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,3WGK7@541000|Ruminococcaceae	186801|Clostridia	C	CBS domain	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
NGKEMLHH_02021	1121115.AXVN01000021_gene1704	3.26e-200	556.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia,3XZE6@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
NGKEMLHH_02022	1121115.AXVN01000021_gene1703	9.78e-156	437.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,3XZH1@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	spoT	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NGKEMLHH_02023	1121115.AXVN01000021_gene1702	1.84e-90	266.0	2EY21@1|root,33RAZ@2|Bacteria,1VSPZ@1239|Firmicutes,24YUD@186801|Clostridia,3Y1ZI@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
NGKEMLHH_02024	1121115.AXVN01000021_gene1701	1.79e-215	595.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3XZGB@572511|Blautia	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
NGKEMLHH_02025	457412.RSAG_03304	0.0	1446.0	COG0457@1|root,COG0464@1|root,COG0457@2|Bacteria,COG0464@2|Bacteria,1TY3C@1239|Firmicutes,248IE@186801|Clostridia,3WGDF@541000|Ruminococcaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	SpoVK	-	-	-	-	-	-	-	-	-	-	-	TPR_8
NGKEMLHH_02026	1121115.AXVN01000021_gene1699	2.51e-261	716.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3XZEV@572511|Blautia	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
NGKEMLHH_02027	1121115.AXVN01000021_gene1698	1.81e-41	136.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,3Y0NB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
NGKEMLHH_02028	457412.RSAG_03307	4.51e-260	713.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,3WGZ2@541000|Ruminococcaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
NGKEMLHH_02029	1121115.AXVN01000021_gene1696	0.0	889.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,3XYQ0@572511|Blautia	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
NGKEMLHH_02030	457412.RSAG_03309	1.37e-21	84.3	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,3WM8B@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
NGKEMLHH_02031	457412.RSAG_03310	6.74e-80	237.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,3WKGV@541000|Ruminococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
NGKEMLHH_02032	457412.RSAG_03311	1.52e-47	151.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,3WKGN@541000|Ruminococcaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
NGKEMLHH_02033	457412.RSAG_03312	1.95e-289	793.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,3WHYT@541000|Ruminococcaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
NGKEMLHH_02034	457412.RSAG_03313	6.44e-195	543.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3WHR4@541000|Ruminococcaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
NGKEMLHH_02035	1121115.AXVN01000021_gene1692	0.0	878.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,3XYJS@572511|Blautia	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
NGKEMLHH_02036	1121115.AXVN01000021_gene1691	0.0	1218.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,3XYJA@572511|Blautia	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
NGKEMLHH_02037	1121115.AXVN01000021_gene1690	2.4e-171	478.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,3XYIZ@572511|Blautia	186801|Clostridia	H	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
NGKEMLHH_02038	457412.RSAG_03317	7.9e-247	679.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,3WH5S@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_02039	457412.RSAG_01999	1.21e-79	236.0	COG5561@1|root,COG5561@2|Bacteria,1VBDY@1239|Firmicutes,259Y8@186801|Clostridia,3WQWE@541000|Ruminococcaceae	186801|Clostridia	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
NGKEMLHH_02040	1121115.AXVN01000092_gene78	2.76e-212	588.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,3Y281@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02041	457412.RSAG_01997	0.0	1790.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,3WH08@541000|Ruminococcaceae	186801|Clostridia	J	elongation factor G	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
NGKEMLHH_02042	1121115.AXVN01000092_gene76	5.11e-107	309.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia,3XZZN@572511|Blautia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
NGKEMLHH_02043	1121115.AXVN01000092_gene75	0.0	1094.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3XYUW@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
NGKEMLHH_02044	457412.RSAG_01994	6.39e-158	442.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,3WS4K@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_02045	457412.RSAG_01993	0.0	864.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WGB6@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
NGKEMLHH_02046	1121115.AXVN01000092_gene72	5.81e-313	852.0	COG1653@1|root,COG1653@2|Bacteria,1TPBF@1239|Firmicutes,24920@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_02047	1121115.AXVN01000092_gene71	5.28e-221	609.0	COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,247WN@186801|Clostridia,3XZJ7@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NGKEMLHH_02048	1121115.AXVN01000092_gene70	3.23e-310	844.0	COG1653@1|root,COG1653@2|Bacteria,1TPBF@1239|Firmicutes,24920@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_02049	1378168.N510_03305	1.48e-170	479.0	COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes	1239|Firmicutes	L	site-specific DNA-methyltransferase (Adenine-specific)	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
NGKEMLHH_02050	1378168.N510_03306	1.36e-229	652.0	COG1578@1|root,COG1578@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF89	-	-	-	-	-	-	-	-	-	-	-	-	RE_AlwI
NGKEMLHH_02051	1121115.AXVN01000003_gene1600	1.83e-183	510.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,3XYPW@572511|Blautia	186801|Clostridia	D	cell division inhibitor, membrane ATPase MinD	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
NGKEMLHH_02052	1121115.AXVN01000003_gene1599	0.0	1269.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,3XZEI@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	cooS1	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
NGKEMLHH_02053	1499684.CCNP01000023_gene3306	1.08e-12	80.5	28NUE@1|root,2ZBST@2|Bacteria,1V25Z@1239|Firmicutes,24H99@186801|Clostridia,36MRP@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02054	1121115.AXVN01000107_gene609	0.0	1422.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
NGKEMLHH_02055	1123075.AUDP01000004_gene845	4.03e-36	135.0	COG2110@1|root,COG2365@1|root,COG2110@2|Bacteria,COG2365@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,3WH35@541000|Ruminococcaceae	186801|Clostridia	T	domain protein	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
NGKEMLHH_02056	1235790.C805_00891	1.3e-156	452.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,25VI0@186806|Eubacteriaceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_02057	97139.C824_01278	1.91e-29	105.0	29B13@1|root,2ZXZY@2|Bacteria,1W529@1239|Firmicutes,256ET@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02058	97139.C824_04422	2.61e-117	336.0	29B9C@1|root,2ZY7Q@2|Bacteria,1V4QD@1239|Firmicutes,24GPW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02059	908937.Prede_2103	2.89e-10	67.8	COG4977@1|root,COG4977@2|Bacteria,4PKX4@976|Bacteroidetes,2FNFD@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NGKEMLHH_02060	1536774.H70357_01370	1.17e-40	148.0	COG4225@1|root,COG4225@2|Bacteria,1UY6X@1239|Firmicutes,4HEUH@91061|Bacilli,275QP@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
NGKEMLHH_02061	1121115.AXVN01000148_gene3603	5.92e-119	340.0	2EGBC@1|root,33A36@2|Bacteria,1UKIB@1239|Firmicutes,24VNX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02062	1121115.AXVN01000148_gene3602	0.0	1771.0	COG4403@1|root,COG4403@2|Bacteria,1TS6F@1239|Firmicutes,247JU@186801|Clostridia,3XZVN@572511|Blautia	186801|Clostridia	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
NGKEMLHH_02063	1121115.AXVN01000012_gene3115	0.0	1307.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y14N@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
NGKEMLHH_02064	457412.RSAG_02749	3.28e-232	637.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,3WN40@541000|Ruminococcaceae	186801|Clostridia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
NGKEMLHH_02065	457412.RSAG_01347	1.04e-54	171.0	2CM8T@1|root,32SE0@2|Bacteria,1VBP1@1239|Firmicutes,24Q65@186801|Clostridia	186801|Clostridia	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
NGKEMLHH_02066	1121115.AXVN01000041_gene2594	1.38e-82	244.0	COG1598@1|root,COG1598@2|Bacteria,1VAII@1239|Firmicutes,24I04@186801|Clostridia	186801|Clostridia	S	HicB family	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB,HicB_lk_antitox
NGKEMLHH_02068	1121115.AXVN01000041_gene2595	0.0	893.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,3XYYT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
NGKEMLHH_02069	457412.RSAG_01344	9.27e-121	345.0	COG3707@1|root,COG3707@2|Bacteria,1V2S1@1239|Firmicutes,24EWG@186801|Clostridia,3WK4K@541000|Ruminococcaceae	186801|Clostridia	K	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR
NGKEMLHH_02071	1232447.BAHW02000015_gene1096	9.59e-55	203.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02073	1121115.AXVN01000001_gene1105	3.15e-38	127.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3Y0IR@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
NGKEMLHH_02074	457412.RSAG_01211	2.07e-124	354.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,3WJHK@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
NGKEMLHH_02075	457412.RSAG_01212	1.21e-305	833.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
NGKEMLHH_02076	457412.RSAG_01213	1.34e-232	641.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,3WGX7@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Phosphate acetyl butaryl transferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
NGKEMLHH_02077	457412.RSAG_04661	1.83e-313	855.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,3WI9X@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
NGKEMLHH_02078	1121115.AXVN01000001_gene1110	1.48e-178	498.0	COG2865@1|root,COG2865@2|Bacteria,1TQXE@1239|Firmicutes,249ND@186801|Clostridia,3XZUK@572511|Blautia	186801|Clostridia	K	COG NOG11764 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02079	1121115.AXVN01000001_gene1111	4.34e-85	251.0	COG1340@1|root,COG1340@2|Bacteria,1V7S0@1239|Firmicutes,24KZW@186801|Clostridia	186801|Clostridia	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
NGKEMLHH_02080	457412.RSAG_01218	9.86e-100	291.0	2CJ2H@1|root,33QUA@2|Bacteria,1VSMM@1239|Firmicutes,24Z9D@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
NGKEMLHH_02081	1121115.AXVN01000001_gene1113	3.3e-298	814.0	COG0038@1|root,COG0038@2|Bacteria,1UZ4F@1239|Firmicutes,24921@186801|Clostridia	186801|Clostridia	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
NGKEMLHH_02082	1121115.AXVN01000001_gene1114	3.69e-187	520.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3Y16A@572511|Blautia	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
NGKEMLHH_02083	457412.RSAG_01221	2.57e-200	557.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3WGQG@541000|Ruminococcaceae	186801|Clostridia	P	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
NGKEMLHH_02084	1121115.AXVN01000001_gene1116	3.29e-235	648.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3XZPA@572511|Blautia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
NGKEMLHH_02085	457412.RSAG_00877	5.05e-79	234.0	COG0662@1|root,COG0662@2|Bacteria,1V7HI@1239|Firmicutes,24JQZ@186801|Clostridia,3WPJX@541000|Ruminococcaceae	186801|Clostridia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NGKEMLHH_02086	457412.RSAG_03509	6.83e-76	226.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia,3WJW2@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, HxlR family	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
NGKEMLHH_02087	457412.RSAG_02205	7.99e-37	124.0	2CDFN@1|root,32SPI@2|Bacteria,1VE6M@1239|Firmicutes,24MYF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02088	457412.RSAG_02206	8.47e-87	256.0	2D5KY@1|root,32TJC@2|Bacteria,1VD7P@1239|Firmicutes,253JR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02089	457412.RSAG_02207	1.08e-286	783.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,3WH96@541000|Ruminococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NGKEMLHH_02090	457412.RSAG_01040	0.0	1328.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WJT6@541000|Ruminococcaceae	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NGKEMLHH_02091	457412.RSAG_01041	6.48e-211	582.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WGF4@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
NGKEMLHH_02092	411459.RUMOBE_02019	8.38e-193	535.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,3XZR8@572511|Blautia	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
NGKEMLHH_02094	411459.RUMOBE_02017	0.0	1095.0	COG0814@1|root,COG0814@2|Bacteria,1V9NE@1239|Firmicutes,25FHY@186801|Clostridia,3XZUD@572511|Blautia	186801|Clostridia	E	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
NGKEMLHH_02095	1121115.AXVN01000011_gene3447	1.78e-208	576.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,3XYTN@572511|Blautia	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
NGKEMLHH_02096	1121115.AXVN01000011_gene3446	3.47e-154	432.0	COG4656@1|root,COG4656@2|Bacteria,1TS9H@1239|Firmicutes,24DQ7@186801|Clostridia,3XYYU@572511|Blautia	186801|Clostridia	C	Methylene-tetrahydrofolate reductase C terminal	metV	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS18525	MTHFR_C
NGKEMLHH_02097	457412.RSAG_02335	0.0	1072.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,MTHFR_C,RnfC_N,SLBB
NGKEMLHH_02098	1121115.AXVN01000056_gene2502	0.0	1462.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,3XZ2P@572511|Blautia	186801|Clostridia	MV	COG COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NGKEMLHH_02099	1121115.AXVN01000056_gene2501	6.36e-153	430.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3XYM9@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_02100	1121115.AXVN01000065_gene680	1.07e-35	121.0	2CHQ1@1|root,3240C@2|Bacteria,1UQE2@1239|Firmicutes,25855@186801|Clostridia,3Y1Z3@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02101	457412.RSAG_01473	2.72e-78	233.0	COG5658@1|root,COG5658@2|Bacteria,1VFT9@1239|Firmicutes	1239|Firmicutes	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
NGKEMLHH_02102	457412.RSAG_01474	4.55e-76	227.0	2EQJM@1|root,33I5N@2|Bacteria,1VPBW@1239|Firmicutes,24WG5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02103	457412.RSAG_01475	2.95e-45	147.0	2C5R4@1|root,30J7R@2|Bacteria,1TTNT@1239|Firmicutes,24Q7C@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NGKEMLHH_02104	471875.RUMLAC_02183	3.76e-156	443.0	COG3464@1|root,COG3464@2|Bacteria,1VE6P@1239|Firmicutes,24EJ6@186801|Clostridia,3WP3G@541000|Ruminococcaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
NGKEMLHH_02105	471875.RUMLAC_02182	2.38e-136	391.0	COG3464@1|root,COG3464@2|Bacteria,1VDMT@1239|Firmicutes,24N28@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
NGKEMLHH_02106	1121115.AXVN01000132_gene730	3.55e-162	454.0	COG0546@1|root,COG0546@2|Bacteria,1UHUD@1239|Firmicutes,25E2T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NGKEMLHH_02107	457412.RSAG_02429	0.0	1428.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WGKX@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NGKEMLHH_02108	1121115.AXVN01000025_gene959	0.0	1754.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3XYY3@572511|Blautia	186801|Clostridia	C	COG COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	mop	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
NGKEMLHH_02109	457412.RSAG_00924	0.0	1044.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,3WH9C@541000|Ruminococcaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
NGKEMLHH_02110	1121115.AXVN01000002_gene1361	2.47e-77	231.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,3Y05W@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
NGKEMLHH_02111	457412.RSAG_00926	6.24e-39	129.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
NGKEMLHH_02112	1121115.AXVN01000002_gene1360	3.5e-33	116.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia,3Y06K@572511|Blautia	186801|Clostridia	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
NGKEMLHH_02113	457412.RSAG_00673	9.29e-307	838.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,3WHDK@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_02114	457412.RSAG_00674	3.63e-248	681.0	COG2267@1|root,COG2267@2|Bacteria,1V2IH@1239|Firmicutes,24BN4@186801|Clostridia,3WPQY@541000|Ruminococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
NGKEMLHH_02115	1121115.AXVN01000043_gene3386	1.95e-69	221.0	COG2211@1|root,COG2211@2|Bacteria,1TR5B@1239|Firmicutes,249ZF@186801|Clostridia,3Y1AU@572511|Blautia	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NGKEMLHH_02116	748449.Halha_0416	7.88e-42	149.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,25C41@186801|Clostridia	186801|Clostridia	L	Phage integrase SAM-like domain	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_5,Phage_integrase
NGKEMLHH_02117	1105031.HMPREF1141_2503	1.41e-79	240.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,36EF8@31979|Clostridiaceae	186801|Clostridia	P	PFAM Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
NGKEMLHH_02118	1280692.AUJL01000001_gene314	1.03e-59	198.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,36EWJ@31979|Clostridiaceae	186801|Clostridia	M	LICD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
NGKEMLHH_02119	1396.DJ87_3939	1.84e-44	162.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HCW0@91061|Bacilli,1ZFI5@1386|Bacillus	91061|Bacilli	S	COG0463 Glycosyltransferases involved in cell wall biogenesis	epsJ	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K19425,ko:K19427	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
NGKEMLHH_02120	1280668.ATVT01000008_gene587	3.98e-26	112.0	COG1035@1|root,COG3955@1|root,COG1035@2|Bacteria,COG3955@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia,4BZCS@830|Butyrivibrio	186801|Clostridia	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N
NGKEMLHH_02121	411462.DORLON_01613	6.54e-64	211.0	COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,24N29@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NGKEMLHH_02122	1449342.JQMR01000001_gene86	6.68e-34	135.0	COG3274@1|root,COG3274@2|Bacteria,1V0QX@1239|Firmicutes,4HFH3@91061|Bacilli,27FV5@186828|Carnobacteriaceae	91061|Bacilli	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NGKEMLHH_02123	1304284.L21TH_1874	2.26e-113	352.0	COG2244@1|root,COG2244@2|Bacteria,1TQ51@1239|Firmicutes,24DRX@186801|Clostridia,36G90@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
NGKEMLHH_02124	760154.Sulba_1864	2.99e-93	292.0	COG1035@1|root,COG1145@1|root,COG1035@2|Bacteria,COG1145@2|Bacteria,1RDME@1224|Proteobacteria,42RMC@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N
NGKEMLHH_02125	445973.CLOBAR_02315	7.94e-121	362.0	COG2327@1|root,COG2327@2|Bacteria,1UZDY@1239|Firmicutes,24BCV@186801|Clostridia	186801|Clostridia	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
NGKEMLHH_02126	411462.DORLON_01613	2.79e-74	238.0	COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,24N29@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NGKEMLHH_02127	411462.DORLON_01611	1.33e-112	337.0	COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes	1239|Firmicutes	M	Glycosyltransferase group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NGKEMLHH_02128	411467.BACCAP_01615	3.47e-140	410.0	COG0438@1|root,COG0438@2|Bacteria,1UZ0I@1239|Firmicutes,25BIM@186801|Clostridia,269DE@186813|unclassified Clostridiales	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
NGKEMLHH_02129	742722.HMPREF9463_01431	2.37e-46	155.0	COG1045@1|root,COG1045@2|Bacteria,2GQAY@201174|Actinobacteria	201174|Actinobacteria	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2
NGKEMLHH_02130	457412.RSAG_02264	9.32e-252	691.0	COG2391@1|root,COG2391@2|Bacteria,1TPWG@1239|Firmicutes,249KU@186801|Clostridia,3WIA9@541000|Ruminococcaceae	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
NGKEMLHH_02131	457412.RSAG_02263	8.68e-278	759.0	COG0675@1|root,COG0675@2|Bacteria,1TT4J@1239|Firmicutes,24CV7@186801|Clostridia,3WR4V@541000|Ruminococcaceae	186801|Clostridia	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
NGKEMLHH_02132	457412.RSAG_02262	1.94e-91	267.0	COG1943@1|root,COG1943@2|Bacteria,1V5MU@1239|Firmicutes,24HFH@186801|Clostridia	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
NGKEMLHH_02133	1121115.AXVN01000037_gene3266	0.0	1493.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3XYPZ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	ybhJ	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
NGKEMLHH_02134	457412.RSAG_00072	8.78e-56	177.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,3WJDB@541000|Ruminococcaceae	186801|Clostridia	S	heptaprenyl diphosphate synthase	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
NGKEMLHH_02135	1121115.AXVN01000002_gene1434	1.22e-76	229.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3Y0CQ@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
NGKEMLHH_02136	457412.RSAG_00070	0.0	1165.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
NGKEMLHH_02137	457412.RSAG_00069	8.38e-46	147.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24QS3@186801|Clostridia,3WKYW@541000|Ruminococcaceae	186801|Clostridia	C	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
NGKEMLHH_02138	457412.RSAG_03025	2.54e-213	589.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,3WGJ2@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
NGKEMLHH_02139	1121115.AXVN01000005_gene2243	0.0	1338.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25ACE@186801|Clostridia,3XZNB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
NGKEMLHH_02140	457412.RSAG_02246	0.0	1066.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3WISX@541000|Ruminococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13889	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	SBP_bac_5
NGKEMLHH_02141	1121115.AXVN01000028_gene209	1.76e-206	572.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3Y02S@572511|Blautia	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13890	ko02010,map02010	M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.11	-	-	BPD_transp_1
NGKEMLHH_02142	272563.CD630_33260	1.77e-280	767.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24EQM@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NGKEMLHH_02143	1121115.AXVN01000141_gene2384	2.06e-38	128.0	2ARET@1|root,31GQW@2|Bacteria,1TUXE@1239|Firmicutes,25NXF@186801|Clostridia,3Y0Q5@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3173
NGKEMLHH_02144	411902.CLOBOL_04437	7.33e-50	158.0	2AJW5@1|root,3037X@2|Bacteria,1TTSU@1239|Firmicutes,25NPB@186801|Clostridia,2215C@1506553|Lachnoclostridium	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NGKEMLHH_02145	411902.CLOBOL_04436	1.39e-96	281.0	COG1595@1|root,COG1595@2|Bacteria,1TSMC@1239|Firmicutes,24FTZ@186801|Clostridia,221Z1@1506553|Lachnoclostridium	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
NGKEMLHH_02146	1121115.AXVN01000046_gene2990	3.58e-212	587.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3XZDE@572511|Blautia	186801|Clostridia	M	UDP-N-acetylenolpyruvoylglucosamine reductase	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
NGKEMLHH_02147	457412.RSAG_02839	9.96e-212	585.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,3WGDD@541000|Ruminococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
NGKEMLHH_02148	1121115.AXVN01000046_gene2988	3.83e-232	640.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,3XYJH@572511|Blautia	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
NGKEMLHH_02149	457412.RSAG_00227	0.0	1253.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3WHN6@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HATPase_c,HD,HD_5,Response_reg
NGKEMLHH_02150	1121115.AXVN01000049_gene1310	0.0	1398.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3XZDZ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
NGKEMLHH_02151	457412.RSAG_02911	5.23e-229	630.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,3WHA2@541000|Ruminococcaceae	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
NGKEMLHH_02152	1121115.AXVN01000037_gene3251	0.0	1132.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3Y19R@572511|Blautia	186801|Clostridia	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
NGKEMLHH_02153	1121115.AXVN01000037_gene3252	4.82e-190	536.0	COG1070@1|root,COG1070@2|Bacteria,1TSEJ@1239|Firmicutes,24AT3@186801|Clostridia,3Y1CK@572511|Blautia	186801|Clostridia	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NGKEMLHH_02154	457412.RSAG_04662	0.0	1932.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,3WH4V@541000|Ruminococcaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
NGKEMLHH_02155	1121115.AXVN01000001_gene1096	8.03e-159	445.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3XZ9W@572511|Blautia	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
NGKEMLHH_02156	1121115.AXVN01000001_gene1097	6.78e-42	137.0	COG0236@1|root,COG0236@2|Bacteria,1UGNP@1239|Firmicutes,25P5Y@186801|Clostridia,3Y0KT@572511|Blautia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NGKEMLHH_02157	1121115.AXVN01000001_gene1098	6.17e-238	655.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,3XYGR@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
NGKEMLHH_02158	1121115.AXVN01000001_gene1099	0.0	1160.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,3XZ7N@572511|Blautia	186801|Clostridia	S	COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NGKEMLHH_02159	457412.RSAG_01205	1.65e-177	496.0	2ESCZ@1|root,33JXR@2|Bacteria,1VRFX@1239|Firmicutes,24YXB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02160	457412.RSAG_01206	3.82e-168	470.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24C2K@186801|Clostridia,3WRJJ@541000|Ruminococcaceae	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NGKEMLHH_02161	1121115.AXVN01000001_gene1102	0.0	1228.0	COG3290@1|root,COG5002@1|root,COG3290@2|Bacteria,COG5002@2|Bacteria,1VC62@1239|Firmicutes,25E8N@186801|Clostridia,3Y0QU@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NGKEMLHH_02162	457412.RSAG_01208	1.3e-300	835.0	2E7W1@1|root,332AT@2|Bacteria,1UYG9@1239|Firmicutes,24B0R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02163	1121115.AXVN01000010_gene2753	0.0	1050.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia,3XZ3F@572511|Blautia	186801|Clostridia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
NGKEMLHH_02164	1121115.AXVN01000003_gene1598	9.12e-135	384.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,3XZK1@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
NGKEMLHH_02165	1121115.AXVN01000003_gene1597	0.0	1405.0	COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3XZDK@572511|Blautia	186801|Clostridia	C	acetyl-CoA decarbonylase synthase complex subunit beta	cdhC	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
NGKEMLHH_02166	457412.RSAG_04541	1.31e-205	570.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WN6I@541000|Ruminococcaceae	186801|Clostridia	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
NGKEMLHH_02167	457412.RSAG_02788	2.41e-290	798.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_02168	457412.RSAG_02787	1.19e-45	147.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24QS3@186801|Clostridia,3WKYW@541000|Ruminococcaceae	186801|Clostridia	C	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
NGKEMLHH_02169	1121115.AXVN01000084_gene1827	0.0	1219.0	COG0515@1|root,COG4886@1|root,COG0515@2|Bacteria,COG4886@2|Bacteria,1V7U3@1239|Firmicutes,24G0F@186801|Clostridia,3Y202@572511|Blautia	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
NGKEMLHH_02170	1121115.AXVN01000084_gene1826	9.55e-88	258.0	2E529@1|root,32ZVG@2|Bacteria,1VGFJ@1239|Firmicutes,2502W@186801|Clostridia,3Y24M@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02171	411459.RUMOBE_02134	6.26e-146	412.0	COG0619@1|root,COG0619@2|Bacteria,1UVFB@1239|Firmicutes,25MDZ@186801|Clostridia,3Y0VN@572511|Blautia	186801|Clostridia	P	COG COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters	-	-	-	-	-	-	-	-	-	-	-	-	CbiQ
NGKEMLHH_02172	411459.RUMOBE_02133	2.43e-138	391.0	2DBJF@1|root,2Z9KJ@2|Bacteria,1TQXS@1239|Firmicutes,25CIQ@186801|Clostridia	186801|Clostridia	S	Hypothetical bacterial integral membrane protein (Trep_Strep)	-	-	-	-	-	-	-	-	-	-	-	-	Trep_Strep
NGKEMLHH_02173	411459.RUMOBE_02132	2.78e-117	339.0	COG4977@1|root,COG4977@2|Bacteria,1UK39@1239|Firmicutes,25FHZ@186801|Clostridia,3Y1JI@572511|Blautia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NGKEMLHH_02174	1121115.AXVN01000054_gene1880	1.19e-80	239.0	COG2002@1|root,COG2002@2|Bacteria,1V8G8@1239|Firmicutes,24JVE@186801|Clostridia	186801|Clostridia	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02175	1121115.AXVN01000054_gene1879	2.64e-63	193.0	COG2026@1|root,COG2026@2|Bacteria,1V7AZ@1239|Firmicutes,24KDM@186801|Clostridia	186801|Clostridia	DJ	ParE-like toxin of type II bacterial toxin-antitoxin system	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE-like_toxin
NGKEMLHH_02176	457412.RSAG_02716	0.0	1065.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3WH77@541000|Ruminococcaceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NGKEMLHH_02177	457412.RSAG_00348	4.54e-268	736.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGI6@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
NGKEMLHH_02178	1121115.AXVN01000009_gene1460	7.72e-196	544.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,24F3Z@186801|Clostridia,3XZMZ@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
NGKEMLHH_02179	1469948.JPNB01000001_gene447	1.07e-77	251.0	2F3Y4@1|root,33WQ6@2|Bacteria,1UKAG@1239|Firmicutes,24JVD@186801|Clostridia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NGKEMLHH_02180	515620.EUBELI_20069	2.02e-27	110.0	COG3279@1|root,COG3279@2|Bacteria,1V0X7@1239|Firmicutes,24EP3@186801|Clostridia,25XIK@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score 8.87	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
NGKEMLHH_02183	658088.HMPREF0987_01922	1.16e-92	277.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,27J9V@186928|unclassified Lachnospiraceae	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
NGKEMLHH_02184	658088.HMPREF0987_01922	1.94e-92	276.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,27J9V@186928|unclassified Lachnospiraceae	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
NGKEMLHH_02185	33035.JPJF01000104_gene2581	2.15e-172	483.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,3XZBU@572511|Blautia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NGKEMLHH_02186	658088.HMPREF0987_01924	8.54e-54	168.0	29URZ@1|root,30G41@2|Bacteria,1TU3V@1239|Firmicutes,2587H@186801|Clostridia,27PQ8@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02193	1384065.JAGS01000001_gene524	1.17e-57	192.0	COG5585@1|root,COG5585@2|Bacteria,1UZ0K@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ADPrib_exo_Tox,Phage_min_cap2
NGKEMLHH_02194	471875.RUMLAC_00178	0.0	992.0	COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,249YY@186801|Clostridia,3WMAS@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer	csn1	-	-	ko:K09952	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas9-BH,Cas9_PI,Cas9_REC,HNH_4
NGKEMLHH_02195	1408324.JNJK01000037_gene3743	2.86e-127	370.0	COG1518@1|root,COG1518@2|Bacteria,1TT0J@1239|Firmicutes,24CB1@186801|Clostridia,27K7W@186928|unclassified Lachnospiraceae	186801|Clostridia	L	CRISPR associated protein Cas1	cas1	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas1
NGKEMLHH_02196	1321820.HMPREF1983_01245	9.97e-40	134.0	COG3512@1|root,COG3512@2|Bacteria,1VEH4@1239|Firmicutes,4HNYR@91061|Bacilli,3WFMX@539002|Bacillales incertae sedis	91061|Bacilli	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
NGKEMLHH_02199	1121115.AXVN01000057_gene2512	5.58e-41	135.0	2EJPA@1|root,33DE4@2|Bacteria,1VPMV@1239|Firmicutes,24VGY@186801|Clostridia,3Y26U@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02200	1121115.AXVN01000057_gene2511	0.0	1004.0	COG5421@1|root,COG5421@2|Bacteria,1UQ6M@1239|Firmicutes,24CF5@186801|Clostridia	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_02203	362663.ECP_1914	0.0	975.0	COG0507@1|root,COG0507@2|Bacteria,1MUTR@1224|Proteobacteria,1RQS3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NGKEMLHH_02204	199310.c2398	1.61e-223	615.0	COG4916@1|root,COG4916@2|Bacteria,1MXWM@1224|Proteobacteria,1SYTX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
NGKEMLHH_02205	693746.OBV_32590	7.99e-31	138.0	28NUE@1|root,2ZBST@2|Bacteria,1V25Z@1239|Firmicutes,24H99@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02206	97139.C824_04655	1.49e-162	462.0	28IZW@1|root,2Z8X6@2|Bacteria,1UZN3@1239|Firmicutes,24CUS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02207	552396.HMPREF0863_00419	5.72e-62	189.0	2C5U6@1|root,330NX@2|Bacteria,1VGSI@1239|Firmicutes,3VS47@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02208	552396.HMPREF0863_00420	4.52e-223	614.0	28JS8@1|root,2Z9HS@2|Bacteria,1UY4F@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02209	515622.bpr_I2107	7.56e-283	785.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,4BXHP@830|Butyrivibrio	186801|Clostridia	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
NGKEMLHH_02210	411490.ANACAC_02418	1.76e-235	649.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24XW6@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NGKEMLHH_02211	658086.HMPREF0994_00631	4.64e-288	799.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	hag	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
NGKEMLHH_02212	658086.HMPREF0994_00630	2.78e-235	646.0	COG2227@1|root,COG2227@2|Bacteria,1VTJX@1239|Firmicutes,24DS4@186801|Clostridia	186801|Clostridia	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02213	457412.RSAG_01521	9.07e-211	584.0	COG1172@1|root,COG1172@2|Bacteria,1U0FI@1239|Firmicutes,24B5S@186801|Clostridia,3WPSA@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NGKEMLHH_02214	457412.RSAG_01522	0.0	971.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3WGJM@541000|Ruminococcaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
NGKEMLHH_02215	457412.RSAG_01523	6.74e-46	155.0	COG1172@1|root,COG1172@2|Bacteria,1UVPQ@1239|Firmicutes,25MGQ@186801|Clostridia,3WPXD@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
NGKEMLHH_02220	1519439.JPJG01000022_gene552	2.77e-42	144.0	COG1396@1|root,COG1396@2|Bacteria,1UM3W@1239|Firmicutes,25GA1@186801|Clostridia	186801|Clostridia	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_02221	1235799.C818_03007	2.47e-21	85.9	2DCK0@1|root,2ZEG2@2|Bacteria,1W2D4@1239|Firmicutes,255S2@186801|Clostridia,27SV0@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02222	1256908.HMPREF0373_00822	0.0	868.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,25WG7@186806|Eubacteriaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
NGKEMLHH_02223	658088.HMPREF0987_01131	8.17e-87	254.0	COG1403@1|root,COG1403@2|Bacteria,1V9Y6@1239|Firmicutes,25DN2@186801|Clostridia,27NAU@186928|unclassified Lachnospiraceae	186801|Clostridia	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
NGKEMLHH_02224	658088.HMPREF0987_01130	6.2e-112	320.0	COG1961@1|root,COG1961@2|Bacteria,1VA99@1239|Firmicutes,24MZH@186801|Clostridia,27M7F@186928|unclassified Lachnospiraceae	186801|Clostridia	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02225	658088.HMPREF0987_01129	1.18e-313	853.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,249MR@186801|Clostridia,27IY4@186928|unclassified Lachnospiraceae	186801|Clostridia	KL	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
NGKEMLHH_02226	658088.HMPREF0987_01128	2.9e-313	852.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,27KBU@186928|unclassified Lachnospiraceae	186801|Clostridia	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
NGKEMLHH_02227	658655.HMPREF0988_00551	3.91e-168	471.0	2948F@1|root,32SNR@2|Bacteria,1V5VX@1239|Firmicutes,24IET@186801|Clostridia,27M7Y@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02228	658655.HMPREF0988_00550	2.02e-216	597.0	28HR1@1|root,2Z7YI@2|Bacteria,1TRNR@1239|Firmicutes,2486X@186801|Clostridia,27JS2@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative amidoligase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Amidoligase_2
NGKEMLHH_02229	658655.HMPREF0988_00549	6.42e-101	293.0	COG2105@1|root,COG2105@2|Bacteria,1VDAD@1239|Firmicutes,24G9Y@186801|Clostridia,27TP0@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
NGKEMLHH_02230	658655.HMPREF0988_00548	1.67e-86	254.0	COG2105@1|root,COG2105@2|Bacteria,1VGQA@1239|Firmicutes,24S5K@186801|Clostridia,27Q1R@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4314
NGKEMLHH_02232	658655.HMPREF0988_00546	1.38e-112	323.0	COG3747@1|root,COG3747@2|Bacteria,1V0EC@1239|Firmicutes,24GCB@186801|Clostridia,27K65@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage terminase, small subunit	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_4
NGKEMLHH_02233	658655.HMPREF0988_00545	0.0	1064.0	COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,27IKB@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage Terminase	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_3,Terminase_1
NGKEMLHH_02234	658088.HMPREF0987_01121	6.06e-312	848.0	COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,27I52@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
NGKEMLHH_02235	658088.HMPREF0987_01120	2.57e-159	447.0	COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,249NC@186801|Clostridia,27JST@186928|unclassified Lachnospiraceae	186801|Clostridia	OU	Serine dehydrogenase proteinase	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NGKEMLHH_02236	658088.HMPREF0987_01119	2.53e-283	775.0	COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes,24994@186801|Clostridia,27J63@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
NGKEMLHH_02237	658088.HMPREF0987_01118	4.64e-53	167.0	2E3C8@1|root,32YBI@2|Bacteria,1VETG@1239|Firmicutes,24QPC@186801|Clostridia,27PYH@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage gp6-like head-tail connector protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_connect_1
NGKEMLHH_02238	1449063.JMLS01000001_gene4204	1.01e-09	60.1	COG2207@1|root,COG2207@2|Bacteria,1W15F@1239|Firmicutes,4HPZ7@91061|Bacilli,26TIU@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NGKEMLHH_02239	1122917.KB899686_gene3276	1.2e-216	626.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,4HDGR@91061|Bacilli,26R3B@186822|Paenibacillaceae	91061|Bacilli	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
NGKEMLHH_02240	1121115.AXVN01000031_gene323	4.1e-44	153.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NGKEMLHH_02241	457412.RSAG_00424	1.14e-126	362.0	COG1122@1|root,COG1122@2|Bacteria,1TSSM@1239|Firmicutes,249KS@186801|Clostridia,3WJNC@541000|Ruminococcaceae	186801|Clostridia	P	AAA domain, putative AbiEii toxin, Type IV TA system	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
NGKEMLHH_02242	457412.RSAG_00423	1.1e-131	373.0	COG4636@1|root,COG4636@2|Bacteria,1V1Q1@1239|Firmicutes,24ITV@186801|Clostridia,3WS1U@541000|Ruminococcaceae	1239|Firmicutes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NGKEMLHH_02243	511680.BUTYVIB_01914	9.55e-06	45.8	2E4DC@1|root,32Z8R@2|Bacteria,1VF6A@1239|Firmicutes,24QX7@186801|Clostridia,4C00Y@830|Butyrivibrio	186801|Clostridia	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	ko:K19165	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
NGKEMLHH_02244	1121115.AXVN01000020_gene100	3.38e-17	75.1	COG3077@1|root,COG3077@2|Bacteria,1VJC4@1239|Firmicutes,25CY3@186801|Clostridia	186801|Clostridia	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
NGKEMLHH_02245	457412.RSAG_00420	5.1e-123	350.0	COG4636@1|root,COG4636@2|Bacteria,1V5WZ@1239|Firmicutes,24IWJ@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NGKEMLHH_02246	457412.RSAG_00419	2.04e-129	367.0	COG4636@1|root,COG4636@2|Bacteria,1V8DJ@1239|Firmicutes,24G93@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NGKEMLHH_02247	33035.JPJF01000035_gene3480	9.39e-182	534.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,25KCW@186801|Clostridia,3Y11X@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
NGKEMLHH_02249	1121115.AXVN01000014_gene1229	1.98e-233	652.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NGKEMLHH_02250	1121115.AXVN01000014_gene1230	5.31e-132	387.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1VSN8@1239|Firmicutes,24YS7@186801|Clostridia,3Y1SB@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NGKEMLHH_02251	1121115.AXVN01000014_gene1230	4.97e-210	590.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1VSN8@1239|Firmicutes,24YS7@186801|Clostridia,3Y1SB@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NGKEMLHH_02252	411469.EUBHAL_02111	1.48e-167	469.0	COG1349@1|root,COG1349@2|Bacteria,1TSUV@1239|Firmicutes,24CQC@186801|Clostridia,25V7E@186806|Eubacteriaceae	186801|Clostridia	GK	Replication initiator protein A (RepA) N-terminus	repA	-	-	-	-	-	-	-	-	-	-	-	RepA_N
NGKEMLHH_02253	929506.CbC4_2046	2.86e-136	390.0	COG1484@1|root,COG1484@2|Bacteria,1TPPI@1239|Firmicutes,24DKZ@186801|Clostridia,36I94@31979|Clostridiaceae	186801|Clostridia	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
NGKEMLHH_02254	290402.Cbei_4287	3.84e-189	539.0	COG4584@1|root,COG4584@2|Bacteria,1UYE8@1239|Firmicutes,25D03@186801|Clostridia,36U51@31979|Clostridiaceae	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
NGKEMLHH_02255	457412.RSAG_02784	1.34e-257	706.0	COG3608@1|root,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,3WJ0E@541000|Ruminococcaceae	186801|Clostridia	Q	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
NGKEMLHH_02256	457412.RSAG_02785	1.55e-79	236.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3WK18@541000|Ruminococcaceae	186801|Clostridia	K	regulatory protein, arsR	czrA	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
NGKEMLHH_02257	457412.RSAG_02786	3.15e-199	566.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
NGKEMLHH_02258	1121115.AXVN01000035_gene3850	7.83e-153	429.0	COG1838@1|root,COG1838@2|Bacteria,1TSJ8@1239|Firmicutes,25CDD@186801|Clostridia,3Y19V@572511|Blautia	186801|Clostridia	C	Fumarase C-terminus	ttdB	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
NGKEMLHH_02259	457412.RSAG_02928	1.01e-223	615.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3WGE0@541000|Ruminococcaceae	186801|Clostridia	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.32	ko:K03779	ko00630,map00630	-	R00339	RC01382	ko00000,ko00001,ko01000	-	-	-	Fumerase
NGKEMLHH_02260	1121115.AXVN01000035_gene3852	1.38e-228	635.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,24D6M@186801|Clostridia,3XZZY@572511|Blautia	186801|Clostridia	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp
NGKEMLHH_02261	742735.HMPREF9467_03110	2.42e-33	116.0	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,24MDN@186801|Clostridia,221HQ@1506553|Lachnoclostridium	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NGKEMLHH_02262	999413.HMPREF1094_00556	5.18e-24	92.4	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,3VU5D@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NGKEMLHH_02263	742735.HMPREF9467_03110	1.88e-28	103.0	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,24MDN@186801|Clostridia,221HQ@1506553|Lachnoclostridium	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NGKEMLHH_02264	742735.HMPREF9467_03107	3.48e-17	75.9	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes	1239|Firmicutes	S	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NGKEMLHH_02265	1321372.AQQB01000051_gene1448	2.46e-290	794.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,4HCFN@91061|Bacilli,1WU1W@1307|Streptococcus suis	91061|Bacilli	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase,Rep_3
NGKEMLHH_02268	936596.HMPREF1495_2573	5.4e-11	69.3	COG2176@1|root,COG2176@2|Bacteria,1V3E4@1239|Firmicutes,249X5@186801|Clostridia,1HUD8@1164882|Lachnoanaerobaculum	186801|Clostridia	L	Exonuclease	-	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
NGKEMLHH_02269	457412.RSAG_00229	6.01e-141	397.0	2ESIJ@1|root,33K39@2|Bacteria,1VP26@1239|Firmicutes,25HRK@186801|Clostridia,3WMIB@541000|Ruminococcaceae	186801|Clostridia	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
NGKEMLHH_02270	457412.RSAG_00228	0.0	1051.0	COG0791@1|root,COG0791@2|Bacteria,1UVPP@1239|Firmicutes,25KKC@186801|Clostridia,3WQIY@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
NGKEMLHH_02271	457412.RSAG_01055	1.88e-273	749.0	COG0477@1|root,COG0477@2|Bacteria,1TS50@1239|Firmicutes,24BE2@186801|Clostridia,3WKIP@541000|Ruminococcaceae	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NGKEMLHH_02272	457412.RSAG_01056	5.11e-209	578.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WI65@541000|Ruminococcaceae	186801|Clostridia	C	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
NGKEMLHH_02273	457412.RSAG_01057	0.0	1271.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WH0G@541000|Ruminococcaceae	186801|Clostridia	C	NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NGKEMLHH_02274	457412.RSAG_01058	4.74e-207	572.0	COG1082@1|root,COG1082@2|Bacteria,1TT50@1239|Firmicutes,248RM@186801|Clostridia,3WN3B@541000|Ruminococcaceae	186801|Clostridia	L	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NGKEMLHH_02275	457412.RSAG_01059	5.81e-219	603.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia,3WJ83@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NGKEMLHH_02276	1121115.AXVN01000001_gene1041	7.61e-179	499.0	COG0703@1|root,COG1605@1|root,COG0703@2|Bacteria,COG1605@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3XZNC@572511|Blautia	186801|Clostridia	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
NGKEMLHH_02277	457412.RSAG_01061	2.95e-304	828.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WGET@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NGKEMLHH_02278	1121115.AXVN01000001_gene1043	9.84e-192	531.0	COG0770@1|root,COG0770@2|Bacteria,1V1NG@1239|Firmicutes,24GE1@186801|Clostridia,3Y02I@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
NGKEMLHH_02279	457412.RSAG_01064	1.94e-129	368.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,3WJD2@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
NGKEMLHH_02280	457412.RSAG_01065	1.89e-184	513.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,3WJM6@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
NGKEMLHH_02281	1121115.AXVN01000001_gene1046	2.92e-17	78.6	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,3XZYI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NGKEMLHH_02282	457412.RSAG_01628	8.8e-136	388.0	COG0791@1|root,COG0791@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,3WRJN@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
NGKEMLHH_02283	1121115.AXVN01000018_gene53	0.0	1164.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia,3XYKE@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
NGKEMLHH_02284	1121115.AXVN01000034_gene3861	1.85e-99	290.0	COG1329@1|root,COG1329@2|Bacteria,1VAA0@1239|Firmicutes,24P60@186801|Clostridia,3Y0SQ@572511|Blautia	186801|Clostridia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
NGKEMLHH_02285	1121115.AXVN01000034_gene3862	2.11e-182	516.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3XYNC@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_02286	1121115.AXVN01000034_gene3862	4.16e-112	333.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3XYNC@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_02287	1121115.AXVN01000034_gene3863	3.62e-137	388.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia	186801|Clostridia	F	COG NOG14451 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NGKEMLHH_02288	457412.RSAG_00391	3.8e-177	494.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,3WJ55@541000|Ruminococcaceae	186801|Clostridia	GM	Transport permease protein	pyrL	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
NGKEMLHH_02289	1121115.AXVN01000004_gene1956	5.19e-169	473.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3XYUG@572511|Blautia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score 9.49	rfbB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_02290	457412.RSAG_00389	2.43e-265	726.0	COG1835@1|root,COG1835@2|Bacteria,1VEDZ@1239|Firmicutes,259Z5@186801|Clostridia,3WQXI@541000|Ruminococcaceae	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NGKEMLHH_02291	1121115.AXVN01000113_gene2375	1.81e-102	301.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,3XZBU@572511|Blautia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NGKEMLHH_02292	1121115.AXVN01000113_gene2374	1.52e-210	582.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,3XYKZ@572511|Blautia	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
NGKEMLHH_02293	1121115.AXVN01000113_gene2373	2.51e-235	647.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,3XZD0@572511|Blautia	186801|Clostridia	S	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
NGKEMLHH_02294	1121115.AXVN01000113_gene2372	1.36e-56	176.0	2C39Y@1|root,32RBW@2|Bacteria,1V801@1239|Firmicutes,24JSG@186801|Clostridia,3Y1QC@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02295	1121115.AXVN01000119_gene3269	3.78e-120	344.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,3Y01B@572511|Blautia	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
NGKEMLHH_02296	1121373.KB903640_gene3733	1.12e-05	55.8	COG0515@1|root,COG0515@2|Bacteria,4PKQ1@976|Bacteroidetes,47XYP@768503|Cytophagia	976|Bacteroidetes	KLT	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
NGKEMLHH_02297	1384065.JAGS01000005_gene3446	0.000133	53.9	COG1404@1|root,COG2373@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2373@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.45,3.4.24.3	ko:K01201,ko:K01387,ko:K14645	ko00511,ko00600,ko01100,ko02024,ko04142,map00511,map00600,map01100,map02024,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000,ko01002,ko02042,ko03110	-	GH30	-	Peptidase_S8,SLH
NGKEMLHH_02298	457412.RSAG_01032	3.24e-147	416.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WIDU@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
NGKEMLHH_02299	1121115.AXVN01000019_gene162	1.66e-213	589.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,25E67@186801|Clostridia,3XYNX@572511|Blautia	186801|Clostridia	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
NGKEMLHH_02300	31234.CRE04458	4.75e-147	415.0	COG1131@1|root,KOG0059@2759|Eukaryota	2759|Eukaryota	V	ATPase activity, coupled to transmembrane movement of substances	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NGKEMLHH_02301	469008.B21_02777	2.67e-177	494.0	COG1682@1|root,COG1682@2|Bacteria,1MUTE@1224|Proteobacteria,1RZ4T@1236|Gammaproteobacteria,3XNK3@561|Escherichia	1236|Gammaproteobacteria	GM	ABC-2 type transporter	kpsM	-	-	ko:K09688	ko02010,map02010	M00249	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.101	-	-	ABC2_membrane
NGKEMLHH_02302	1121115.AXVN01000001_gene1123	1.61e-73	221.0	2ETPV@1|root,33M7I@2|Bacteria,1VNHF@1239|Firmicutes,25A5M@186801|Clostridia,3Y0Q4@572511|Blautia	186801|Clostridia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
NGKEMLHH_02303	457412.RSAG_01230	5.73e-271	754.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3WG9V@541000|Ruminococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NGKEMLHH_02304	1121115.AXVN01000041_gene2590	2.74e-28	102.0	2C5R4@1|root,2ZP19@2|Bacteria,1W6F9@1239|Firmicutes,255YP@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NGKEMLHH_02305	457412.RSAG_01352	5.95e-50	158.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NGKEMLHH_02306	1121115.AXVN01000041_gene2588	2.79e-89	261.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24HXG@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NGKEMLHH_02307	457412.RSAG_01354	2.62e-209	587.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3WGBX@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
NGKEMLHH_02308	1121115.AXVN01000042_gene3017	2.51e-197	547.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,3XYU8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NGKEMLHH_02309	1121115.AXVN01000042_gene3016	2.76e-120	343.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia,3Y05S@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02310	1121115.AXVN01000042_gene3015	7.42e-75	223.0	COG0745@1|root,COG0745@2|Bacteria,1UK3F@1239|Firmicutes,25FI6@186801|Clostridia,3Y0KY@572511|Blautia	186801|Clostridia	KT	Sporulation initiation factor Spo0A C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
NGKEMLHH_02311	1121115.AXVN01000042_gene3014	0.0	1360.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,3XZ94@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
NGKEMLHH_02312	457412.RSAG_01730	0.0	1481.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	ArabFuran-catal,CHU_C,DUF11,IgGFc_binding,LTD,NPCBM_assoc,Peptidase_M11,SprB
NGKEMLHH_02313	457412.RSAG_01731	1.94e-50	160.0	2E51P@1|root,32ZV2@2|Bacteria,1VFYG@1239|Firmicutes,24QWN@186801|Clostridia,3WKYT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02314	1121115.AXVN01000042_gene3011	1.82e-189	526.0	COG0561@1|root,COG0561@2|Bacteria,1V43V@1239|Firmicutes,24AQQ@186801|Clostridia,3XZTP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NGKEMLHH_02315	1121115.AXVN01000042_gene3010	1.11e-162	454.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia,3XZXU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NGKEMLHH_02316	457412.RSAG_01734	4.92e-136	385.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WJIZ@541000|Ruminococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
NGKEMLHH_02317	1121115.AXVN01000042_gene3008	2.69e-46	153.0	2F1AC@1|root,33UBB@2|Bacteria,1VUR2@1239|Firmicutes,2503K@186801|Clostridia,3Y24T@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02318	457412.RSAG_01736	0.0	1133.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,3WH6G@541000|Ruminococcaceae	186801|Clostridia	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
NGKEMLHH_02319	742733.HMPREF9469_00779	3.48e-120	349.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,21ZJV@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NGKEMLHH_02320	1298920.KI911353_gene1741	0.0	954.0	COG3345@1|root,COG3345@2|Bacteria,1TSZB@1239|Firmicutes,247VV@186801|Clostridia,222P9@1506553|Lachnoclostridium	186801|Clostridia	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
NGKEMLHH_02321	411468.CLOSCI_02512	5.63e-81	252.0	COG1028@1|root,COG1028@2|Bacteria,1TSBE@1239|Firmicutes,25B52@186801|Clostridia,2245H@1506553|Lachnoclostridium	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NGKEMLHH_02322	1105031.HMPREF1141_3217	1.93e-90	278.0	COG1082@1|root,COG1082@2|Bacteria,1UYHR@1239|Firmicutes,25C7S@186801|Clostridia,36GZK@31979|Clostridiaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016854,GO:0016857,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050897	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
NGKEMLHH_02323	1121115.AXVN01000006_gene2180	9.41e-115	330.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,3XYJ2@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
NGKEMLHH_02324	457412.RSAG_00833	0.0	868.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,3WGP4@541000|Ruminococcaceae	186801|Clostridia	P	K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NGKEMLHH_02325	457412.RSAG_04630	2.46e-157	442.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,3WHWM@541000|Ruminococcaceae	186801|Clostridia	P	acid ABC transporter	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
NGKEMLHH_02326	457412.RSAG_02362	1.62e-172	481.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3WGJA@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type polar amino acid transport system ATPase component	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
NGKEMLHH_02327	457412.RSAG_02363	1.04e-219	607.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,3WND9@541000|Ruminococcaceae	186801|Clostridia	S	Sodium Bile acid symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SBF
NGKEMLHH_02328	1121115.AXVN01000016_gene3687	2.54e-77	230.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia,3Y07B@572511|Blautia	186801|Clostridia	S	COG COG0517 FOG CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
NGKEMLHH_02329	585394.RHOM_16720	1.95e-17	81.3	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
NGKEMLHH_02330	180332.JTGN01000016_gene1038	0.0	991.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_02331	585394.RHOM_14195	1.8e-10	60.5	COG0770@1|root,COG0770@2|Bacteria,1TS8M@1239|Firmicutes,24CJW@186801|Clostridia	186801|Clostridia	M	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
NGKEMLHH_02332	1120746.CCNL01000005_gene273	5.51e-77	236.0	2DBGD@1|root,2Z948@2|Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K16926	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.31	-	-	Trep_Strep
NGKEMLHH_02333	1235802.C823_02666	1.06e-62	202.0	COG0619@1|root,COG0619@2|Bacteria,1V375@1239|Firmicutes,24GJ7@186801|Clostridia,25ZT8@186806|Eubacteriaceae	186801|Clostridia	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
NGKEMLHH_02334	1121098.HMPREF1534_02622	3.14e-29	107.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,2FRY7@200643|Bacteroidia,4AQIR@815|Bacteroidaceae	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
NGKEMLHH_02335	435590.BVU_0808	2.3e-106	307.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
NGKEMLHH_02336	1121115.AXVN01000005_gene2276	2.21e-177	494.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,3XZWD@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	fnt	-	-	ko:K02598	-	-	-	-	ko00000,ko02000	1.A.16.3	-	-	Form_Nir_trans
NGKEMLHH_02337	658088.HMPREF0987_01138	4.76e-196	550.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,27J0X@186928|unclassified Lachnospiraceae	186801|Clostridia	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SNF2_N
NGKEMLHH_02338	658088.HMPREF0987_01137	4.1e-111	319.0	2DN5I@1|root,32VNS@2|Bacteria,1VA6J@1239|Firmicutes,24HYW@186801|Clostridia,27NM8@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02339	658088.HMPREF0987_01136	3.5e-81	240.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24KXM@186801|Clostridia,27NI8@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
NGKEMLHH_02341	658088.HMPREF0987_01134	2.38e-66	201.0	292K7@1|root,2ZQ45@2|Bacteria,1W3HV@1239|Firmicutes,256NF@186801|Clostridia,27S8N@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02342	742765.HMPREF9457_03059	5.46e-279	764.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,24AH4@186801|Clostridia,27W37@189330|Dorea	186801|Clostridia	L	COG COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NGKEMLHH_02343	483218.BACPEC_02571	8.32e-17	77.8	28MNT@1|root,2ZAY9@2|Bacteria,1UJWE@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02344	457412.RSAG_02803	7.29e-257	719.0	COG0451@1|root,COG0451@2|Bacteria,1UYUX@1239|Firmicutes,24CYP@186801|Clostridia,3WKD2@541000|Ruminococcaceae	186801|Clostridia	GM	Domain of unknown function (DUF4118)	-	-	5.1.3.2	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,RmlD_sub_bind
NGKEMLHH_02345	457412.RSAG_02802	2.31e-183	512.0	28H6W@1|root,2Z7J7@2|Bacteria,1TPV9@1239|Firmicutes,24CD2@186801|Clostridia,3WMQ4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02346	457412.RSAG_02801	0.0	1222.0	COG4878@1|root,COG4878@2|Bacteria,1TT2Y@1239|Firmicutes,24A4C@186801|Clostridia,3WIQH@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised protein conserved in bacteria (DUF2194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2194
NGKEMLHH_02347	457412.RSAG_02800	0.0	987.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,24BAM@186801|Clostridia,3WGGZ@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF3492)	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glycos_transf_1
NGKEMLHH_02348	457412.RSAG_02799	0.0	930.0	COG4267@1|root,COG4267@2|Bacteria,1TRZE@1239|Firmicutes,24EQ7@186801|Clostridia,3WKMX@541000|Ruminococcaceae	186801|Clostridia	S	Putative exopolysaccharide Exporter (EPS-E)	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
NGKEMLHH_02349	457412.RSAG_02798	0.0	1162.0	COG5337@1|root,COG5337@2|Bacteria,1U5H9@1239|Firmicutes,249YX@186801|Clostridia,3WI9H@541000|Ruminococcaceae	186801|Clostridia	M	CotH kinase protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
NGKEMLHH_02350	457412.RSAG_02797	8.7e-179	498.0	COG5036@1|root,COG5036@2|Bacteria,1TYFN@1239|Firmicutes,24AGZ@186801|Clostridia,3WJCF@541000|Ruminococcaceae	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
NGKEMLHH_02351	457412.RSAG_02796	2.78e-148	418.0	COG1285@1|root,COG1285@2|Bacteria,1TRUW@1239|Firmicutes,248G4@186801|Clostridia,3WHWK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
NGKEMLHH_02352	457412.RSAG_02795	0.0	930.0	COG1874@1|root,COG1874@2|Bacteria,1TRPS@1239|Firmicutes,24AH9@186801|Clostridia,3WIPR@541000|Ruminococcaceae	186801|Clostridia	G	Domain of unknown function (DUF4832)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,Glyco_hydro_42
NGKEMLHH_02353	457412.RSAG_02794	7.51e-121	352.0	COG3385@1|root,COG3385@2|Bacteria,1UNGW@1239|Firmicutes,24BMP@186801|Clostridia,3WK14@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
NGKEMLHH_02354	411470.RUMGNA_01390	1.07e-108	320.0	COG3385@1|root,COG3385@2|Bacteria,1UNGW@1239|Firmicutes,24BMP@186801|Clostridia,3Y1GW@572511|Blautia	186801|Clostridia	L	COG NOG14195 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_02355	1321778.HMPREF1982_00900	8.43e-108	321.0	COG4211@1|root,COG4211@2|Bacteria,1UI1K@1239|Firmicutes,25EAQ@186801|Clostridia,267VT@186813|unclassified Clostridiales	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	mglC	-	-	ko:K10541	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	BPD_transp_2
NGKEMLHH_02356	1345697.M493_09710	3.32e-227	656.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,1WEKS@129337|Geobacillus	91061|Bacilli	G	Fibronectin type III-like domain	-	-	3.2.1.21,3.2.1.52	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	M00628	R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko00002,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NGKEMLHH_02357	1121115.AXVN01000047_gene1251	6.06e-267	736.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,3XZ35@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
NGKEMLHH_02358	1121115.AXVN01000047_gene1250	2.68e-255	699.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3XZFI@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
NGKEMLHH_02359	1121115.AXVN01000007_gene3533	2.29e-119	342.0	2ESEK@1|root,33JZA@2|Bacteria,1VNHH@1239|Firmicutes,24UXF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02360	1121115.AXVN01000007_gene3532	2.45e-161	458.0	COG3935@1|root,COG3935@2|Bacteria,1VCAM@1239|Firmicutes,24E45@186801|Clostridia	186801|Clostridia	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02361	1121115.AXVN01000007_gene3532	4.1e-67	213.0	COG3935@1|root,COG3935@2|Bacteria,1VCAM@1239|Firmicutes,24E45@186801|Clostridia	186801|Clostridia	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02363	428125.CLOLEP_00803	0.0	1231.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WGFQ@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2,RVT_1
NGKEMLHH_02367	1121115.AXVN01000004_gene2002	0.0	1195.0	2EXAA@1|root,33QKY@2|Bacteria,1VU9D@1239|Firmicutes,24Y4F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02368	1121115.AXVN01000004_gene2003	2.19e-111	320.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,3Y0EF@572511|Blautia	186801|Clostridia	K	COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NGKEMLHH_02369	457412.RSAG_03445	1.15e-166	469.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,248J4@186801|Clostridia,3WGM8@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
NGKEMLHH_02370	1121115.AXVN01000153_gene3988	1.62e-165	462.0	COG0132@1|root,COG0132@2|Bacteria,1UYA3@1239|Firmicutes,24F15@186801|Clostridia,3Y0X3@572511|Blautia	186801|Clostridia	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
NGKEMLHH_02371	457412.RSAG_03443	1.05e-298	813.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,3WHN3@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77	ko:K00833,ko:K03851,ko:K12256,ko:K15372	ko00330,ko00410,ko00430,ko00780,ko01100,map00330,map00410,map00430,map00780,map01100	M00123,M00573,M00577	R00908,R01684,R03231,R05652,R08714	RC00006,RC00008,RC00062,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NGKEMLHH_02372	1123075.AUDP01000004_gene869	2.97e-73	242.0	COG3629@1|root,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,24AC8@186801|Clostridia,3WJNS@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,GGDEF,Trans_reg_C
NGKEMLHH_02374	1280679.ATVX01000009_gene1690	9.92e-24	99.8	COG1525@1|root,COG1525@2|Bacteria,1UX9P@1239|Firmicutes,25N2Z@186801|Clostridia,4C19W@830|Butyrivibrio	186801|Clostridia	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02375	546275.FUSPEROL_00855	1.18e-36	132.0	COG4186@1|root,COG4186@2|Bacteria,378QT@32066|Fusobacteria	32066|Fusobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
NGKEMLHH_02379	1121115.AXVN01000078_gene2827	1.77e-137	389.0	COG4720@1|root,COG4720@2|Bacteria,1USKD@1239|Firmicutes,24A2K@186801|Clostridia,3XZIW@572511|Blautia	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
NGKEMLHH_02380	457412.RSAG_01921	7.4e-292	798.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
NGKEMLHH_02381	457412.RSAG_01920	1.18e-233	645.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,3WJ50@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NGKEMLHH_02382	1121115.AXVN01000078_gene2830	3.03e-197	547.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,3Y0BN@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NGKEMLHH_02383	1121115.AXVN01000078_gene2831	0.0	903.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3XZQF@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_02384	457412.RSAG_01914	8.13e-214	592.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3WGMM@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
NGKEMLHH_02385	457412.RSAG_01913	0.0	1335.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk1	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
NGKEMLHH_02387	457412.RSAG_01912	5.51e-241	665.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,3WIAE@541000|Ruminococcaceae	186801|Clostridia	L	PFAM Transposase, Mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
NGKEMLHH_02388	1121115.AXVN01000086_gene3999	4.49e-89	261.0	2EYFK@1|root,33RPH@2|Bacteria,1VT8U@1239|Firmicutes,24XWV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02392	457412.RSAG_02780	1e-137	389.0	COG1309@1|root,COG1309@2|Bacteria,1U1ZX@1239|Firmicutes,24ERU@186801|Clostridia,3WRWC@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NGKEMLHH_02393	457412.RSAG_02781	1.86e-89	262.0	COG1895@1|root,COG1895@2|Bacteria,1VG5F@1239|Firmicutes,24RT7@186801|Clostridia,3WMCM@541000|Ruminococcaceae	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
NGKEMLHH_02394	457412.RSAG_02782	8.61e-75	223.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
NGKEMLHH_02395	457412.RSAG_00021	2.62e-279	770.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
NGKEMLHH_02396	1235798.C817_05113	1.35e-122	351.0	COG1309@1|root,COG1309@2|Bacteria,1V2BY@1239|Firmicutes,24PUI@186801|Clostridia	186801|Clostridia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	WHG
NGKEMLHH_02397	1235798.C817_05112	3.48e-150	424.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,27UQG@189330|Dorea	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NGKEMLHH_02398	1121115.AXVN01000004_gene1977	0.0	1105.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,3Y04S@572511|Blautia	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	hgdC_1	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,HGD-D
NGKEMLHH_02399	1121115.AXVN01000004_gene1978	1.35e-271	744.0	COG1775@1|root,COG1775@2|Bacteria,1TS7H@1239|Firmicutes,2493U@186801|Clostridia,3Y0V9@572511|Blautia	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
NGKEMLHH_02400	435590.BVU_3699	2.66e-221	610.0	2DMAX@1|root,32ETX@2|Bacteria,4NQ7I@976|Bacteroidetes,2FQDV@200643|Bacteroidia,4APNW@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02401	435590.BVU_3698	0.0	870.0	COG2452@1|root,COG2452@2|Bacteria,4NQVV@976|Bacteroidetes,2FQS5@200643|Bacteroidia,4AMAV@815|Bacteroidaceae	976|Bacteroidetes	L	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NGKEMLHH_02402	592028.GCWU000321_01531	1.44e-11	72.4	COG0501@1|root,COG0501@2|Bacteria,1VER6@1239|Firmicutes,4H5WC@909932|Negativicutes	909932|Negativicutes	O	Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48
NGKEMLHH_02403	509191.AEDB02000016_gene57	2.29e-167	484.0	COG0433@1|root,COG0433@2|Bacteria,1UY1K@1239|Firmicutes,25ED2@186801|Clostridia	186801|Clostridia	S	TraM recognition site of TraD and TraG	-	-	-	-	-	-	-	-	-	-	-	-	TrwB_AAD_bind
NGKEMLHH_02404	1121115.AXVN01000010_gene2755	3.41e-205	568.0	COG2222@1|root,COG2222@2|Bacteria,1TRTA@1239|Firmicutes,24BGB@186801|Clostridia,3XZXY@572511|Blautia	186801|Clostridia	M	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS
NGKEMLHH_02405	1121115.AXVN01000010_gene2756	4.79e-219	602.0	COG0524@1|root,COG0524@2|Bacteria,1TSST@1239|Firmicutes,24EDX@186801|Clostridia,3Y09Y@572511|Blautia	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
NGKEMLHH_02406	411459.RUMOBE_00629	1.29e-200	556.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,248SU@186801|Clostridia,3XYX7@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02407	411459.RUMOBE_00628	9.29e-82	243.0	28PED@1|root,2ZC92@2|Bacteria,1V3ND@1239|Firmicutes,24G75@186801|Clostridia,3Y0GB@572511|Blautia	186801|Clostridia	S	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
NGKEMLHH_02408	457412.RSAG_02691	3.56e-169	472.0	COG2755@1|root,COG2755@2|Bacteria,1VT0W@1239|Firmicutes,25BMQ@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NGKEMLHH_02409	1121115.AXVN01000124_gene3953	1.97e-151	426.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,3XZ99@572511|Blautia	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
NGKEMLHH_02410	1121115.AXVN01000124_gene3952	3.21e-32	113.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3Y0KZ@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
NGKEMLHH_02411	457412.RSAG_02688	1.16e-87	260.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,3WKJC@541000|Ruminococcaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
NGKEMLHH_02412	1121115.AXVN01000124_gene3950	3.6e-112	322.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia,3Y09Z@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
NGKEMLHH_02413	457412.RSAG_02686	0.0	962.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
NGKEMLHH_02414	457412.RSAG_02685	6.68e-206	570.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3WHJU@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NGKEMLHH_02415	1121115.AXVN01000124_gene3947	0.0	911.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3XYVU@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
NGKEMLHH_02416	1121115.AXVN01000124_gene3946	6.42e-87	256.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,3Y0C9@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
NGKEMLHH_02417	457412.RSAG_02682	0.0	971.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia,3WJKE@541000|Ruminococcaceae	186801|Clostridia	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
NGKEMLHH_02418	457412.RSAG_02681	9.42e-232	638.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,3WGEJ@541000|Ruminococcaceae	186801|Clostridia	M	Linear amide C-N hydrolase, choloylglycine hydrolase family protein	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
NGKEMLHH_02419	457412.RSAG_02679	0.0	1614.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3WI2B@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
NGKEMLHH_02420	457412.RSAG_02678	4.43e-129	367.0	COG1989@1|root,COG1989@2|Bacteria,1VF54@1239|Firmicutes,24RX8@186801|Clostridia,3WKQB@541000|Ruminococcaceae	186801|Clostridia	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
NGKEMLHH_02421	457412.RSAG_02677	1.17e-249	684.0	COG1192@1|root,COG1192@2|Bacteria,1V11K@1239|Firmicutes,24FDX@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
NGKEMLHH_02422	1121115.AXVN01000023_gene1771	1.33e-276	757.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,3XZAC@572511|Blautia	186801|Clostridia	U	flp pilus assembly ATPase CpaF	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
NGKEMLHH_02423	457412.RSAG_02675	1.43e-176	493.0	COG4965@1|root,COG4965@2|Bacteria,1V6PB@1239|Firmicutes,24JBR@186801|Clostridia,3WJUZ@541000|Ruminococcaceae	186801|Clostridia	U	Flp pilus assembly protein TadB	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
NGKEMLHH_02424	457412.RSAG_02674	9.06e-235	647.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia,3WJSN@541000|Ruminococcaceae	186801|Clostridia	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
NGKEMLHH_02425	1121115.AXVN01000023_gene1774	1.49e-32	113.0	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,3Y0UH@572511|Blautia	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
NGKEMLHH_02426	457412.RSAG_02672	0.0	926.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24ASZ@186801|Clostridia,3WISC@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02427	457412.RSAG_02671	2.33e-202	560.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia,3WKZ4@541000|Ruminococcaceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
NGKEMLHH_02428	457412.RSAG_02670	1.1e-98	286.0	2EUKB@1|root,33N28@2|Bacteria,1VMRG@1239|Firmicutes,24U1Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02429	1121115.AXVN01000023_gene1778	8.76e-104	300.0	2EQ3G@1|root,33HPU@2|Bacteria,1VKDW@1239|Firmicutes,24V35@186801|Clostridia,3Y0MK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
NGKEMLHH_02430	457412.RSAG_02668	0.0	955.0	COG1716@1|root,COG1716@2|Bacteria,1V550@1239|Firmicutes,24BVK@186801|Clostridia,3WRV5@541000|Ruminococcaceae	186801|Clostridia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
NGKEMLHH_02431	457412.RSAG_02667	1.07e-134	382.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,3WJRW@541000|Ruminococcaceae	186801|Clostridia	S	PFAM Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
NGKEMLHH_02432	1121115.AXVN01000023_gene1781	1.83e-164	459.0	COG3852@1|root,COG3852@2|Bacteria,1VA7P@1239|Firmicutes,24J8F@186801|Clostridia,3Y29E@572511|Blautia	186801|Clostridia	H	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NGKEMLHH_02433	457412.RSAG_02665	1.85e-95	278.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,3WJ7F@541000|Ruminococcaceae	186801|Clostridia	FG	histidine triad	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
NGKEMLHH_02434	1121115.AXVN01000023_gene1783	1.46e-92	272.0	2DUBI@1|root,33PTJ@2|Bacteria,1VRWC@1239|Firmicutes,24Y88@186801|Clostridia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
NGKEMLHH_02435	1121115.AXVN01000023_gene1784	5.23e-256	702.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3XYKG@572511|Blautia	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
NGKEMLHH_02436	457412.RSAG_02662	1.04e-94	276.0	2EXFY@1|root,33QS9@2|Bacteria,1VU5K@1239|Firmicutes,24YDE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02437	1121115.AXVN01000045_gene2073	1.35e-199	552.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia,3XZZB@572511|Blautia	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
NGKEMLHH_02438	1121115.AXVN01000045_gene2072	0.0	872.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3XYKX@572511|Blautia	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
NGKEMLHH_02439	1121115.AXVN01000045_gene2071	0.0	930.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3XZ1Q@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
NGKEMLHH_02440	1121115.AXVN01000045_gene2070	2.04e-157	442.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3XZJ5@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
NGKEMLHH_02441	1121115.AXVN01000045_gene2069	9.94e-134	381.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,25C2S@186801|Clostridia,3XYV9@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	tcyB	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
NGKEMLHH_02442	1121115.AXVN01000045_gene2068	1.93e-190	531.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3XYR5@572511|Blautia	186801|Clostridia	ET	cystine-binding periplasmic protein precursor	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NGKEMLHH_02443	457412.RSAG_00846	1.12e-172	483.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24D1P@186801|Clostridia,3WJTT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
NGKEMLHH_02444	457412.RSAG_00847	4.42e-312	848.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia,3WK5B@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02445	457412.RSAG_00848	0.0	2373.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia,3WH59@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02446	457412.RSAG_02739	0.0	914.0	COG1653@1|root,COG1653@2|Bacteria,1TSD1@1239|Firmicutes,24BXR@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_02447	1121115.AXVN01000012_gene3100	1.21e-104	302.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3Y2ED@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_02448	411459.RUMOBE_02105	0.0	1284.0	COG4932@1|root,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,2492K@186801|Clostridia,3XZ4G@572511|Blautia	186801|Clostridia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02449	518637.EUBIFOR_00806	1.13e-20	82.4	2ECWX@1|root,336U4@2|Bacteria,1VGNU@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02450	518637.EUBIFOR_00805	2.22e-68	206.0	2AESW@1|root,314PS@2|Bacteria,1V7GZ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02451	411471.SUBVAR_04187	5.85e-38	134.0	COG1175@1|root,COG1175@2|Bacteria,1TSIQ@1239|Firmicutes,25C4Z@186801|Clostridia,3WN7E@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
NGKEMLHH_02452	742735.HMPREF9467_01423	4.07e-154	440.0	COG0395@1|root,COG0395@2|Bacteria,1TR0I@1239|Firmicutes,24AZD@186801|Clostridia,21ZFW@1506553|Lachnoclostridium	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
NGKEMLHH_02453	457421.CBFG_02629	7.04e-237	662.0	COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,249GC@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
NGKEMLHH_02454	1226325.HMPREF1548_03503	2.05e-131	384.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,36FMD@31979|Clostridiaceae	186801|Clostridia	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NGKEMLHH_02456	585394.RHOM_16370	1.75e-263	725.0	COG3290@1|root,COG3290@2|Bacteria,1UZ9P@1239|Firmicutes,24MR7@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NGKEMLHH_02457	483218.BACPEC_02547	3.81e-32	111.0	2EKDM@1|root,33E3X@2|Bacteria,1VP6P@1239|Firmicutes,24WGH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02458	483218.BACPEC_02546	1.16e-128	366.0	COG4512@1|root,COG4512@2|Bacteria,1VJAH@1239|Firmicutes,25BJD@186801|Clostridia	186801|Clostridia	KOT	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07813	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	AgrB
NGKEMLHH_02459	1121115.AXVN01000121_gene2848	0.0	1169.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3XZCN@572511|Blautia	186801|Clostridia	H	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NGKEMLHH_02460	1121115.AXVN01000121_gene2849	9.8e-178	494.0	COG1028@1|root,COG1028@2|Bacteria,1V2KA@1239|Firmicutes,24GZZ@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NGKEMLHH_02461	1121115.AXVN01000037_gene3264	1.06e-257	707.0	COG1879@1|root,COG1879@2|Bacteria,1UZFA@1239|Firmicutes,249QV@186801|Clostridia,3XYTX@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	rbsB_4	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NGKEMLHH_02462	457412.RSAG_01390	5.46e-169	471.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,3WHF8@541000|Ruminococcaceae	186801|Clostridia	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NGKEMLHH_02463	1232447.BAHW02000027_gene2070	5.67e-24	96.3	2DP32@1|root,330AW@2|Bacteria,1VGSG@1239|Firmicutes,24Q56@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02464	411459.RUMOBE_01935	2.17e-32	114.0	2BCQI@1|root,326AY@2|Bacteria,1US91@1239|Firmicutes,25A84@186801|Clostridia,3Y22C@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02465	1256908.HMPREF0373_01452	5.49e-111	320.0	COG1813@1|root,COG1813@2|Bacteria,1V73A@1239|Firmicutes,24GZG@186801|Clostridia,25WVT@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
NGKEMLHH_02466	1256908.HMPREF0373_01453	6.16e-90	264.0	COG3064@1|root,COG3064@2|Bacteria,1VB1V@1239|Firmicutes,24BPB@186801|Clostridia,25Z12@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02467	1256908.HMPREF0373_01454	5.62e-35	120.0	2DQE4@1|root,3368Z@2|Bacteria,1VJUF@1239|Firmicutes,24THC@186801|Clostridia,25Z51@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02468	411459.RUMOBE_01941	4.33e-16	70.5	28XTQ@1|root,2ZJQ5@2|Bacteria,1W1UB@1239|Firmicutes,254MH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02469	272563.CD630_19610	7.57e-85	258.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,25R9H@186804|Peptostreptococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_02471	1391646.AVSU01000111_gene772	1.6e-31	124.0	COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,25SW0@186804|Peptostreptococcaceae	186801|Clostridia	V	Peptidase C39 family	lagD	-	-	ko:K11004,ko:K20344	ko02010,ko02024,ko03070,ko05133,map02010,map02024,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.1,3.A.1.109.2,3.A.1.112	-	-	ABC_membrane,ABC_tran,Peptidase_C39
NGKEMLHH_02472	665956.HMPREF1032_02317	6.96e-250	686.0	COG0270@1|root,COG0270@2|Bacteria,1TR40@1239|Firmicutes,24A8V@186801|Clostridia	186801|Clostridia	H	Cytosine-specific methyltransferase	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
NGKEMLHH_02473	1125700.HMPREF9195_02165	2.28e-40	133.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HTH_17,Response_reg,SpoIIE
NGKEMLHH_02474	665956.HMPREF1032_02316	1.01e-224	620.0	28J8P@1|root,2Z93T@2|Bacteria,1UW2C@1239|Firmicutes,24AZ0@186801|Clostridia,3WHXF@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02475	457412.RSAG_02122	1.45e-192	534.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,248R0@186801|Clostridia,3WKBW@541000|Ruminococcaceae	186801|Clostridia	GM	ABC-2 type transporter	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
NGKEMLHH_02476	1121115.AXVN01000022_gene1724	1.89e-138	390.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,3XYH7@572511|Blautia	186801|Clostridia	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
NGKEMLHH_02477	457412.RSAG_02124	5.71e-299	817.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NGKEMLHH_02478	457412.RSAG_02125	2.71e-284	775.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,3WI1W@541000|Ruminococcaceae	186801|Clostridia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
NGKEMLHH_02479	457412.RSAG_02126	0.0	865.0	COG0027@1|root,COG0027@2|Bacteria,1UKI5@1239|Firmicutes,25FXP@186801|Clostridia,3WIMW@541000|Ruminococcaceae	186801|Clostridia	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
NGKEMLHH_02480	1121115.AXVN01000022_gene1728	1.77e-238	654.0	COG0399@1|root,COG0399@2|Bacteria,1TZB6@1239|Firmicutes,249QE@186801|Clostridia,3Y0S8@572511|Blautia	186801|Clostridia	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02481	1121115.AXVN01000022_gene1729	3.35e-218	602.0	COG0463@1|root,COG0463@2|Bacteria,1TRFA@1239|Firmicutes,249CR@186801|Clostridia,3XZM2@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
NGKEMLHH_02482	1121115.AXVN01000022_gene1730	3.71e-76	227.0	COG0697@1|root,COG0697@2|Bacteria,1UHS0@1239|Firmicutes,25FFB@186801|Clostridia,3Y0C7@572511|Blautia	186801|Clostridia	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NGKEMLHH_02483	457412.RSAG_02130	4.97e-70	211.0	COG2076@1|root,COG2076@2|Bacteria,1VFDI@1239|Firmicutes,24S4I@186801|Clostridia,3WKQ8@541000|Ruminococcaceae	186801|Clostridia	P	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NGKEMLHH_02484	1121115.AXVN01000022_gene1732	0.0	974.0	COG3757@1|root,COG5263@1|root,COG3757@2|Bacteria,COG5263@2|Bacteria,1TPVT@1239|Firmicutes,24DEH@186801|Clostridia,3Y010@572511|Blautia	186801|Clostridia	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Glyco_hydro_25
NGKEMLHH_02485	1121115.AXVN01000022_gene1733	0.0	1521.0	COG1376@1|root,COG5263@1|root,COG1376@2|Bacteria,COG5263@2|Bacteria,1UVCF@1239|Firmicutes,24BKI@186801|Clostridia,3XZR4@572511|Blautia	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,YkuD
NGKEMLHH_02486	1121115.AXVN01000117_gene3355	1.32e-120	351.0	2EWQA@1|root,33Q24@2|Bacteria,1VRMX@1239|Firmicutes,24NS4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02488	1121115.AXVN01000117_gene3357	2.32e-94	275.0	2CUHA@1|root,30KV1@2|Bacteria,1V52Z@1239|Firmicutes,24I1N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02489	411461.DORFOR_00483	3.12e-100	290.0	2B1F5@1|root,31TVV@2|Bacteria,1V9G6@1239|Firmicutes,24KHK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02490	1121115.AXVN01000017_gene258	1.7e-111	320.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia,3XZVY@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
NGKEMLHH_02491	457412.RSAG_00242	2.71e-193	536.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia,3WIEX@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
NGKEMLHH_02492	457412.RSAG_00432	2.19e-106	307.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WRUB@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NGKEMLHH_02493	457412.RSAG_00431	0.0	951.0	2E6HB@1|root,3314J@2|Bacteria,1VGBM@1239|Firmicutes,24T1M@186801|Clostridia,3WMCU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02494	1121115.AXVN01000004_gene1992	1.77e-81	241.0	COG1277@1|root,COG1277@2|Bacteria,1TSXC@1239|Firmicutes,24CZ4@186801|Clostridia,3Y0PT@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
NGKEMLHH_02495	575593.HMPREF0491_03084	3.9e-22	90.5	COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,24BK2@186801|Clostridia,27MGX@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
NGKEMLHH_02496	1121115.AXVN01000153_gene3985	1.66e-101	294.0	COG3610@1|root,COG3610@2|Bacteria,1UVFM@1239|Firmicutes,257UX@186801|Clostridia,3Y1J9@572511|Blautia	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
NGKEMLHH_02497	1121115.AXVN01000153_gene3984	3.4e-178	496.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,3Y0H6@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
NGKEMLHH_02498	742735.HMPREF9467_03110	3.22e-30	108.0	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,24MDN@186801|Clostridia,221HQ@1506553|Lachnoclostridium	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NGKEMLHH_02499	999413.HMPREF1094_00556	1e-23	91.7	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,3VU5D@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NGKEMLHH_02500	742735.HMPREF9467_03110	1.21e-27	101.0	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,24MDN@186801|Clostridia,221HQ@1506553|Lachnoclostridium	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NGKEMLHH_02501	469596.HMPREF9488_02263	1.86e-13	66.6	2E38H@1|root,32Y87@2|Bacteria,1VIF1@1239|Firmicutes,3VU5D@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NGKEMLHH_02502	742735.HMPREF9467_03106	3.02e-253	700.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,21YWZ@1506553|Lachnoclostridium	186801|Clostridia	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_integrase
NGKEMLHH_02503	457412.RSAG_01355	0.0	1541.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3WHE2@541000|Ruminococcaceae	186801|Clostridia	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
NGKEMLHH_02504	457412.RSAG_02755	1.79e-210	580.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,24F6M@186801|Clostridia,3WJRY@541000|Ruminococcaceae	186801|Clostridia	S	Putative esterase	-	-	-	ko:K03930	-	-	-	-	ko00000,ko01000	-	CE1	-	Esterase
NGKEMLHH_02505	1235802.C823_05668	1.87e-43	142.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,25X1K@186806|Eubacteriaceae	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
NGKEMLHH_02506	1121115.AXVN01000012_gene3142	1.81e-238	660.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,25CGY@186801|Clostridia,3XZFH@572511|Blautia	186801|Clostridia	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
NGKEMLHH_02507	1121115.AXVN01000038_gene3341	0.0	954.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XZDA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.17,2.7.1.30	ko:K00854,ko:K00864	ko00040,ko00561,ko01100,ko03320,ko04626,map00040,map00561,map01100,map03320,map04626	M00014	R00847,R01639	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
NGKEMLHH_02508	1121115.AXVN01000038_gene3340	2.15e-290	790.0	COG2220@1|root,COG2220@2|Bacteria,1TSFV@1239|Firmicutes,249MG@186801|Clostridia,3Y1A5@572511|Blautia	186801|Clostridia	S	Beta-lactamase superfamily domain	ulaG	-	-	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	M00550	R07677	RC02793	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactamase_B_2,Lactamase_B_3
NGKEMLHH_02509	1121115.AXVN01000002_gene1420	1.11e-46	150.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia,3Y0MU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02510	457412.RSAG_00054	9.89e-239	655.0	2DUPT@1|root,33RMR@2|Bacteria,1UKHV@1239|Firmicutes,25FXD@186801|Clostridia	186801|Clostridia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NGKEMLHH_02511	1121115.AXVN01000002_gene1418	7.06e-218	600.0	COG0152@1|root,COG0152@2|Bacteria,1UF8J@1239|Firmicutes,25K96@186801|Clostridia,3XZ70@572511|Blautia	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
NGKEMLHH_02512	1121115.AXVN01000024_gene313	1.51e-83	253.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,3Y08K@572511|Blautia	186801|Clostridia	L	Psort location CytoplasmicMembrane, score	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
NGKEMLHH_02513	457412.RSAG_02176	3.83e-163	456.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,3WIDV@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_02514	457412.RSAG_02175	6.03e-270	738.0	COG3503@1|root,COG3503@2|Bacteria,1V89T@1239|Firmicutes,24KHD@186801|Clostridia,3WMMC@541000|Ruminococcaceae	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
NGKEMLHH_02515	1121115.AXVN01000003_gene1615	5.65e-220	606.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3XZRD@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
NGKEMLHH_02516	1121115.AXVN01000003_gene1614	1.64e-74	223.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,3Y019@572511|Blautia	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
NGKEMLHH_02517	457412.RSAG_00631	5.96e-139	393.0	COG0681@1|root,COG0681@2|Bacteria,1V2SF@1239|Firmicutes,24AWM@186801|Clostridia,3WRVN@541000|Ruminococcaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
NGKEMLHH_02518	1121115.AXVN01000003_gene1612	1.46e-202	560.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,3XYWP@572511|Blautia	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
NGKEMLHH_02519	1121115.AXVN01000003_gene1611	6.53e-170	475.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3XZF8@572511|Blautia	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
NGKEMLHH_02520	1121115.AXVN01000003_gene1610	3.51e-86	253.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,3Y0HI@572511|Blautia	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
NGKEMLHH_02521	1121115.AXVN01000003_gene1609	4.57e-211	582.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,3XYQB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
NGKEMLHH_02522	457412.RSAG_00626	1.07e-283	775.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ribose-phosphate pyrophosphokinase family	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
NGKEMLHH_02523	1121115.AXVN01000003_gene1607	0.0	917.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,3XYRJ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
NGKEMLHH_02524	457412.RSAG_00624	3.4e-311	848.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,3WGNU@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
NGKEMLHH_02525	1121115.AXVN01000003_gene1605	2.41e-149	420.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3XZ7V@572511|Blautia	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
NGKEMLHH_02526	1121115.AXVN01000003_gene1604	1.52e-241	664.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,3XYNR@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
NGKEMLHH_02527	1121115.AXVN01000003_gene1603	1.72e-123	356.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,3XYQK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yvgN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NGKEMLHH_02528	457412.RSAG_00482	0.0	956.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3WH27@541000|Ruminococcaceae	186801|Clostridia	S	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NGKEMLHH_02529	1121115.AXVN01000026_gene1019	4.32e-94	275.0	2A2TB@1|root,30R6U@2|Bacteria,1V47K@1239|Firmicutes,24IKY@186801|Clostridia,3Y1K0@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02530	411468.CLOSCI_00937	5.06e-54	176.0	COG3315@1|root,COG3315@2|Bacteria,1TR1Q@1239|Firmicutes,24BWW@186801|Clostridia,223TT@1506553|Lachnoclostridium	186801|Clostridia	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
NGKEMLHH_02531	500632.CLONEX_00484	4.77e-222	613.0	COG2207@1|root,COG2207@2|Bacteria,1TSFI@1239|Firmicutes,249B8@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NGKEMLHH_02532	742740.HMPREF9474_04491	9.08e-135	382.0	2BTE8@1|root,32NKD@2|Bacteria,1W7CP@1239|Firmicutes,25MBX@186801|Clostridia,221U6@1506553|Lachnoclostridium	186801|Clostridia	S	Hypothetical bacterial integral membrane protein (Trep_Strep)	-	-	-	-	-	-	-	-	-	-	-	-	Trep_Strep
NGKEMLHH_02533	483218.BACPEC_01855	1.81e-57	186.0	COG1583@1|root,COG1583@2|Bacteria,1VC7U@1239|Firmicutes,24CJS@186801|Clostridia	186801|Clostridia	L	CRISPR-associated endoribonuclease Cas6	cas6	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas6
NGKEMLHH_02534	537007.BLAHAN_04052	4.8e-227	645.0	28HTI@1|root,2Z80D@2|Bacteria,1TPRZ@1239|Firmicutes,24BPP@186801|Clostridia	186801|Clostridia	S	CRISPR-associated cxxc_cxxc protein Cst1	cst1	-	-	ko:K19088	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CXXC_CXXC
NGKEMLHH_02535	1121115.AXVN01000072_gene3911	0.0	1292.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3XYRF@572511|Blautia	186801|Clostridia	M	Glycosyltransferase like family	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
NGKEMLHH_02536	411459.RUMOBE_00655	1.03e-79	237.0	COG1396@1|root,COG1396@2|Bacteria,1UZN9@1239|Firmicutes,24APP@186801|Clostridia,3Y0S7@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_02538	1235792.C808_02243	1.41e-18	82.4	2BAQE@1|root,3245B@2|Bacteria,1V86A@1239|Firmicutes,24MCZ@186801|Clostridia,27PSB@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02539	411459.RUMOBE_00659	2.07e-75	234.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,3XZD0@572511|Blautia	186801|Clostridia	S	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
NGKEMLHH_02542	411459.RUMOBE_00626	0.0	1226.0	COG0739@1|root,COG0791@1|root,COG3064@1|root,COG3584@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria,COG3064@2|Bacteria,COG3584@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,3XYSD@572511|Blautia	186801|Clostridia	M	Psort location Extracellular, score 9.55	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,Peptidase_M23
NGKEMLHH_02543	457412.RSAG_01583	5.03e-67	203.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3WJWZ@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NGKEMLHH_02544	1121115.AXVN01000087_gene4054	7.59e-48	153.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	3.6.4.12	ko:K03655,ko:K21405	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlbA_2,AsnC_trans_reg,HATPase_c_4,HTH_11,HTH_24,HTH_AsnC-type,rve
NGKEMLHH_02545	457412.RSAG_01585	4.03e-208	576.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,3WJ1R@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NGKEMLHH_02548	1121115.AXVN01000017_gene268	1.06e-63	206.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,3XZHG@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	ywdH	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
NGKEMLHH_02549	1121115.AXVN01000017_gene269	6.41e-129	369.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia	186801|Clostridia	S	RelA SpoT domain protein	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NGKEMLHH_02550	457412.RSAG_00253	7.44e-18	80.1	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,3WIP0@541000|Ruminococcaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NGKEMLHH_02551	457412.RSAG_00254	1.1e-158	444.0	COG1787@1|root,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,24R49@186801|Clostridia,3WKV5@541000|Ruminococcaceae	186801|Clostridia	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Ftsk_gamma,Mrr_cat,zf-C4_Topoisom
NGKEMLHH_02552	457412.RSAG_00255	4.58e-104	302.0	COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,249EP@186801|Clostridia,3WI1J@541000|Ruminococcaceae	186801|Clostridia	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
NGKEMLHH_02553	1121115.AXVN01000132_gene727	6.36e-117	333.0	2CUHA@1|root,30KV1@2|Bacteria,1V52Z@1239|Firmicutes,24I1N@186801|Clostridia,3Y1IQ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02554	1121115.AXVN01000132_gene728	0.0	909.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZ78@572511|Blautia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
NGKEMLHH_02555	1121115.AXVN01000132_gene729	7.81e-29	104.0	2E4IR@1|root,32ZDT@2|Bacteria,1VENP@1239|Firmicutes,24NT8@186801|Clostridia,3Y0CG@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02556	1121115.AXVN01000037_gene3243	1.54e-247	680.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,3XZQ0@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
NGKEMLHH_02557	1121115.AXVN01000037_gene3244	2.92e-34	120.0	COG0716@1|root,COG0716@2|Bacteria,1VB6B@1239|Firmicutes,24GQN@186801|Clostridia,3Y2CS@572511|Blautia	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
NGKEMLHH_02558	1121115.AXVN01000057_gene2515	0.0	1136.0	2DUPK@1|root,33RK6@2|Bacteria,1VRQV@1239|Firmicutes,24YX7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02559	457412.RSAG_02820	3.66e-165	462.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3WG98@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_02560	457412.RSAG_02821	0.0	1596.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,3WGNX@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NGKEMLHH_02561	1121115.AXVN01000057_gene2518	1.92e-308	838.0	COG2159@1|root,COG2159@2|Bacteria,1UZI6@1239|Firmicutes,24EHD@186801|Clostridia	186801|Clostridia	G	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
NGKEMLHH_02562	1121115.AXVN01000057_gene2519	0.0	1808.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3XYWB@572511|Blautia	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
NGKEMLHH_02563	457412.RSAG_00851	6.93e-232	639.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,3WRV6@541000|Ruminococcaceae	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
NGKEMLHH_02564	1121115.AXVN01000045_gene2063	6.82e-308	841.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3XYPM@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_02565	1121115.AXVN01000089_gene2817	3.32e-58	201.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3Y1DS@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
NGKEMLHH_02566	457412.RSAG_02602	5.1e-213	603.0	COG0737@1|root,COG1653@1|root,COG0737@2|Bacteria,COG1653@2|Bacteria,1U6YH@1239|Firmicutes,24ENB@186801|Clostridia,3WNTR@541000|Ruminococcaceae	186801|Clostridia	FG	Bacterial extracellular solute-binding protein	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_02567	1121115.AXVN01000089_gene2816	3.56e-102	312.0	COG0737@1|root,COG1653@1|root,COG0737@2|Bacteria,COG1653@2|Bacteria,1U6YH@1239|Firmicutes,24ENB@186801|Clostridia,3Y15J@572511|Blautia	186801|Clostridia	FG	ABC transporter substrate-binding protein	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_02568	411462.DORLON_01605	7.49e-53	183.0	COG0438@1|root,COG2148@1|root,COG0438@2|Bacteria,COG2148@2|Bacteria,1TQX9@1239|Firmicutes,24874@186801|Clostridia,27WQN@189330|Dorea	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf
NGKEMLHH_02569	411462.DORLON_01608	1.29e-122	364.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,27WG6@189330|Dorea	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
NGKEMLHH_02570	411462.DORLON_01609	1.1e-145	418.0	COG0463@1|root,COG0463@2|Bacteria,1V8T1@1239|Firmicutes,24E8C@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NGKEMLHH_02571	411459.RUMOBE_00586	1.93e-79	236.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,24N11@186801|Clostridia,3Y08G@572511|Blautia	186801|Clostridia	K	beta-lactamase (penicillinase) repressor	blaI	-	-	ko:K02171	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
NGKEMLHH_02572	411459.RUMOBE_00585	1.64e-98	285.0	COG0745@1|root,COG0745@2|Bacteria,1V65U@1239|Firmicutes,24HUB@186801|Clostridia,3Y0QH@572511|Blautia	186801|Clostridia	KT	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
NGKEMLHH_02573	457412.RSAG_00033	4.17e-194	538.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,3WHDE@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
NGKEMLHH_02574	1121115.AXVN01000002_gene1398	7.51e-316	860.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,3Y170@572511|Blautia	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
NGKEMLHH_02575	1410624.JNKK01000008_gene1738	1.15e-101	312.0	COG0719@1|root,COG0719@2|Bacteria,1TRQJ@1239|Firmicutes,24ANC@186801|Clostridia,27MSE@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Uncharacterized protein family (UPF0051)	sufD	-	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
NGKEMLHH_02576	1408436.JHXY01000010_gene883	6.59e-64	208.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,25UTD@186806|Eubacteriaceae	186801|Clostridia	O	assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
NGKEMLHH_02577	411489.CLOL250_02466	5.28e-199	561.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,36G21@31979|Clostridiaceae	186801|Clostridia	O	FeS assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
NGKEMLHH_02578	1122915.AUGY01000020_gene6450	1.79e-117	345.0	COG1082@1|root,COG1082@2|Bacteria,1TRXP@1239|Firmicutes,4HC31@91061|Bacilli,26Z0E@186822|Paenibacillaceae	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NGKEMLHH_02579	556261.HMPREF0240_00724	7.41e-45	162.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,36DBX@31979|Clostridiaceae	186801|Clostridia	G	PFAM periplasmic binding protein	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NGKEMLHH_02581	457412.RSAG_01266	0.0	1050.0	COG4219@1|root,COG4219@2|Bacteria,1TQ0K@1239|Firmicutes,24AVI@186801|Clostridia,3WIKG@541000|Ruminococcaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
NGKEMLHH_02582	457412.RSAG_01267	5.01e-80	237.0	COG3682@1|root,COG3682@2|Bacteria,1V7DH@1239|Firmicutes,24JAQ@186801|Clostridia,3WK0J@541000|Ruminococcaceae	186801|Clostridia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NGKEMLHH_02583	742733.HMPREF9469_05058	1.11e-37	126.0	28WKE@1|root,2ZIKE@2|Bacteria,1W42V@1239|Firmicutes,254Y8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02584	742733.HMPREF9469_05059	7.67e-35	119.0	29UJZ@1|root,30FX8@2|Bacteria,1UETK@1239|Firmicutes,25JT2@186801|Clostridia,223HI@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02585	742733.HMPREF9469_05060	2.61e-127	361.0	2AUTU@1|root,31KGW@2|Bacteria,1V7KU@1239|Firmicutes,24K4D@186801|Clostridia,222Z3@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02586	742733.HMPREF9469_05061	2.84e-33	114.0	2BKWC@1|root,32FCT@2|Bacteria,1UETY@1239|Firmicutes,25JTG@186801|Clostridia,223IF@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02587	742733.HMPREF9469_05062	2.36e-310	844.0	COG0553@1|root,COG0553@2|Bacteria,1TS9W@1239|Firmicutes,24CGX@186801|Clostridia,222GT@1506553|Lachnoclostridium	186801|Clostridia	KL	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02588	1121115.AXVN01000005_gene2245	1.73e-169	474.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,3XYR9@572511|Blautia	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
NGKEMLHH_02589	1121115.AXVN01000005_gene2246	0.0	967.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3XZ0N@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
NGKEMLHH_02591	457412.RSAG_03327	1.33e-187	521.0	292MS@1|root,2ZQ5N@2|Bacteria,1VRQ1@1239|Firmicutes,24ZSR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02592	1121115.AXVN01000021_gene1680	3.81e-224	617.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia,3XZ0E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
NGKEMLHH_02593	1121115.AXVN01000021_gene1681	2.28e-308	840.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3XYK5@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
NGKEMLHH_02594	1121115.AXVN01000021_gene1682	1.11e-113	327.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,3XZYE@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
NGKEMLHH_02595	1121115.AXVN01000021_gene1683	1.77e-215	597.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3XZNQ@572511|Blautia	186801|Clostridia	K	chromosome partitioning protein	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
NGKEMLHH_02596	1121115.AXVN01000021_gene1684	1.32e-176	493.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3XYPE@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NGKEMLHH_02597	1121115.AXVN01000021_gene1685	1.51e-233	642.0	COG0596@1|root,COG0596@2|Bacteria,1TR3M@1239|Firmicutes,24DR9@186801|Clostridia,3XYQ9@572511|Blautia	186801|Clostridia	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
NGKEMLHH_02598	1121115.AXVN01000021_gene1686	0.0	908.0	2DN2J@1|root,32V6S@2|Bacteria,1V1QE@1239|Firmicutes,25HR2@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
NGKEMLHH_02599	1121115.AXVN01000021_gene1687	0.0	943.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia,3XYR3@572511|Blautia	186801|Clostridia	N	ABC-type uncharacterized transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_transp_aux
NGKEMLHH_02600	1121115.AXVN01000021_gene1688	2.03e-82	250.0	COG1277@1|root,COG1277@2|Bacteria,1UZXS@1239|Firmicutes,248ME@186801|Clostridia,3XYVG@572511|Blautia	186801|Clostridia	N	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3,ABC2_membrane_5
NGKEMLHH_02601	1121115.AXVN01000010_gene2785	4.62e-130	374.0	COG4209@1|root,COG4209@2|Bacteria,1TQFY@1239|Firmicutes,24923@186801|Clostridia,3Y19D@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NGKEMLHH_02602	1121115.AXVN01000010_gene2786	2.5e-201	558.0	COG0395@1|root,COG0395@2|Bacteria,1TP1G@1239|Firmicutes,247T2@186801|Clostridia,3Y1FV@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_02603	457412.RSAG_03081	7.56e-303	827.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WGQW@541000|Ruminococcaceae	186801|Clostridia	M	Metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
NGKEMLHH_02604	457412.RSAG_03082	9.65e-271	741.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WGCN@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
NGKEMLHH_02605	411460.RUMTOR_00142	2.9e-42	151.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XZS5@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_02607	476272.RUMHYD_02199	4.88e-263	731.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3XYR0@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
NGKEMLHH_02608	742765.HMPREF9457_02932	1.6e-155	441.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_02610	411459.RUMOBE_00624	1.74e-183	524.0	COG2433@1|root,COG2433@2|Bacteria,1UI9E@1239|Firmicutes,25EEA@186801|Clostridia	186801|Clostridia	T	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
NGKEMLHH_02611	1280698.AUJS01000042_gene3263	7.35e-99	287.0	COG1959@1|root,COG1959@2|Bacteria,1V34F@1239|Firmicutes,24H42@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NGKEMLHH_02612	457412.RSAG_02443	2.46e-219	604.0	COG0846@1|root,COG0846@2|Bacteria,1V192@1239|Firmicutes,24ERM@186801|Clostridia,3WIPW@541000|Ruminococcaceae	186801|Clostridia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02613	411469.EUBHAL_02143	1.39e-67	213.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,247UN@186801|Clostridia,25VAE@186806|Eubacteriaceae	186801|Clostridia	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02614	457412.RSAG_00075	8.42e-190	526.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3WIWA@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
NGKEMLHH_02615	1121115.AXVN01000002_gene1437	2.22e-89	267.0	COG3976@1|root,COG3976@2|Bacteria,1VT26@1239|Firmicutes,25BMN@186801|Clostridia	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
NGKEMLHH_02620	457412.RSAG_03021	8.4e-177	492.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,24A35@186801|Clostridia,3WNN6@541000|Ruminococcaceae	186801|Clostridia	E	Pfam:AHS1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
NGKEMLHH_02621	1121115.AXVN01000005_gene2249	1.46e-240	661.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,2485K@186801|Clostridia,3Y17T@572511|Blautia	186801|Clostridia	E	Pfam:AHS2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
NGKEMLHH_02622	1121115.AXVN01000005_gene2250	8.26e-96	279.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3Y0FB@572511|Blautia	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
NGKEMLHH_02623	457412.RSAG_00049	0.0	1142.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,3WGMQ@541000|Ruminococcaceae	186801|Clostridia	C	hydrogenase large subunit	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,NADH-G_4Fe-4S_3
NGKEMLHH_02624	1121115.AXVN01000002_gene1413	4.89e-147	430.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3XZ6P@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
NGKEMLHH_02638	1095750.HMPREF9970_0745	5.95e-16	72.4	COG1396@1|root,COG1396@2|Bacteria,1VG1N@1239|Firmicutes,24QK8@186801|Clostridia,1HVXP@1164882|Lachnoanaerobaculum	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_02644	556261.HMPREF0240_04057	1.29e-11	62.4	2BDIE@1|root,3277N@2|Bacteria,1UT3K@1239|Firmicutes,2515P@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02648	1235799.C818_02572	1.96e-38	139.0	COG2110@1|root,COG2110@2|Bacteria,1VF6K@1239|Firmicutes,24RMZ@186801|Clostridia	186801|Clostridia	S	Macro domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
NGKEMLHH_02649	658655.HMPREF0988_02511	2.77e-257	709.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,27JJ4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
NGKEMLHH_02650	1121115.AXVN01000071_gene3935	3.05e-175	489.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia,3XZMC@572511|Blautia	186801|Clostridia	S	Uncharacterised protein family UPF0066	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
NGKEMLHH_02651	1121115.AXVN01000071_gene3934	0.0	865.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3XYV0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	thrA	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
NGKEMLHH_02652	457412.RSAG_01779	1.4e-195	541.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,3WIZP@541000|Ruminococcaceae	186801|Clostridia	O	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NGKEMLHH_02653	457412.RSAG_01780	4.59e-195	562.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3WH79@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate formate lyase	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NGKEMLHH_02654	457412.RSAG_00243	4.22e-136	385.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3WJWK@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NGKEMLHH_02655	1121115.AXVN01000017_gene261	5.19e-277	756.0	COG2006@1|root,COG2006@2|Bacteria,1TRYQ@1239|Firmicutes,24966@186801|Clostridia,3XZNX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
NGKEMLHH_02656	1121115.AXVN01000017_gene262	2.76e-90	266.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,3Y0A5@572511|Blautia	186801|Clostridia	I	COG COG0671 Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
NGKEMLHH_02657	1235802.C823_01591	0.0	1486.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1VR4T@1239|Firmicutes,24XZV@186801|Clostridia,25ZFR@186806|Eubacteriaceae	186801|Clostridia	MV	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
NGKEMLHH_02658	1121115.AXVN01000001_gene1166	1.51e-158	448.0	COG0652@1|root,COG0652@2|Bacteria,1V1SP@1239|Firmicutes,24G4H@186801|Clostridia,3XZUZ@572511|Blautia	186801|Clostridia	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
NGKEMLHH_02659	1121115.AXVN01000001_gene1167	1.03e-115	331.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,3XZVQ@572511|Blautia	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
NGKEMLHH_02660	457412.RSAG_01295	9.63e-76	230.0	COG3103@1|root,COG3103@2|Bacteria,1VQZ3@1239|Firmicutes,24XYH@186801|Clostridia	186801|Clostridia	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
NGKEMLHH_02661	1121115.AXVN01000051_gene810	1.96e-71	215.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24UEE@186801|Clostridia	186801|Clostridia	K	helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_02662	1121115.AXVN01000051_gene809	1.57e-93	279.0	COG0791@1|root,COG0791@2|Bacteria,1VICE@1239|Firmicutes,25BYF@186801|Clostridia	186801|Clostridia	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_5,NLPC_P60,SH3_3
NGKEMLHH_02664	457412.RSAG_02818	0.0	1379.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Polysacc_lyase,SLH
NGKEMLHH_02665	1232447.BAHW02000030_gene2323	9.83e-126	371.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,248MY@186801|Clostridia	186801|Clostridia	E	Alcohol dehydrogenase zinc-binding domain protein	-	-	1.1.1.287	ko:K17818	ko00040,ko01100,map00040,map01100	-	R07143,R07144	RC00102	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
NGKEMLHH_02666	180332.JTGN01000006_gene3298	5.05e-92	283.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
NGKEMLHH_02667	1408254.T458_20865	4.42e-39	144.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,26SVT@186822|Paenibacillaceae	91061|Bacilli	G	import. Responsible for energy coupling to the transport system	rbsA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
NGKEMLHH_02668	457412.RSAG_02489	7.83e-267	734.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_02669	457412.RSAG_02489	1.13e-22	95.5	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_02670	457412.RSAG_02488	8.98e-203	564.0	COG1609@1|root,COG1609@2|Bacteria,1UM0E@1239|Firmicutes,25B2H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NGKEMLHH_02671	1121115.AXVN01000037_gene3248	1.68e-274	750.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia,3Y11N@572511|Blautia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
NGKEMLHH_02672	457412.RSAG_02211	1.58e-237	653.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3WM8X@541000|Ruminococcaceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
NGKEMLHH_02673	457412.RSAG_02564	7.8e-142	400.0	COG1102@1|root,COG1102@2|Bacteria,1V74C@1239|Firmicutes,24EKT@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NGKEMLHH_02674	1121115.AXVN01000008_gene2685	0.0	981.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes	1239|Firmicutes	E	amino acid	potE5	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
NGKEMLHH_02675	1121115.AXVN01000008_gene2684	5.51e-48	163.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3Y04D@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R04880,R05233,R05234,R06917,R06927	RC00050,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NGKEMLHH_02676	1121115.AXVN01000008_gene2684	5.34e-196	549.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3Y04D@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R04880,R05233,R05234,R06917,R06927	RC00050,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NGKEMLHH_02677	1121115.AXVN01000008_gene2683	1.02e-152	429.0	COG3341@1|root,COG3341@2|Bacteria,1UIS0@1239|Firmicutes,25EQZ@186801|Clostridia	186801|Clostridia	L	Caulimovirus viroplasmin	rnhA	-	-	ko:K06993	-	-	-	-	ko00000	-	-	-	Cauli_VI,RNase_H
NGKEMLHH_02678	1121115.AXVN01000008_gene2682	2.89e-252	693.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3XZ5V@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
NGKEMLHH_02679	457412.RSAG_02553	2.61e-147	415.0	COG2364@1|root,COG2364@2|Bacteria,1V1ZQ@1239|Firmicutes,24GEW@186801|Clostridia,3WRWZ@541000|Ruminococcaceae	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
NGKEMLHH_02680	1121115.AXVN01000008_gene2680	5.67e-199	552.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,3XYU6@572511|Blautia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
NGKEMLHH_02681	1121115.AXVN01000008_gene2679	3.16e-158	443.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia,3XZ6R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
NGKEMLHH_02682	1121115.AXVN01000008_gene2678	7.75e-299	819.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,3XZ1B@572511|Blautia	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
NGKEMLHH_02683	1121115.AXVN01000008_gene2676	3.04e-217	600.0	COG0583@1|root,COG0583@2|Bacteria,1V5MW@1239|Firmicutes,24J0X@186801|Clostridia,3Y0IH@572511|Blautia	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1
NGKEMLHH_02684	457412.RSAG_01796	1.16e-142	402.0	COG1247@1|root,COG1247@2|Bacteria,1UKI4@1239|Firmicutes,25FXM@186801|Clostridia	186801|Clostridia	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NGKEMLHH_02685	1121115.AXVN01000119_gene3268	3.22e-56	188.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia,3XZRQ@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
NGKEMLHH_02686	1121115.AXVN01000011_gene3442	3.51e-188	524.0	COG0834@1|root,COG0834@2|Bacteria,1VTCR@1239|Firmicutes,24YIS@186801|Clostridia	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
NGKEMLHH_02687	1121115.AXVN01000148_gene3603	6.57e-28	107.0	2EGBC@1|root,33A36@2|Bacteria,1UKIB@1239|Firmicutes,24VNX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02688	457412.RSAG_02817	8.63e-31	110.0	2E98V@1|root,333H5@2|Bacteria,1VI8K@1239|Firmicutes,24RMD@186801|Clostridia	186801|Clostridia	S	BhlA holin family	-	-	-	-	-	-	-	-	-	-	-	-	Holin_BhlA
NGKEMLHH_02691	1121115.AXVN01000005_gene2243	0.0	1110.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25ACE@186801|Clostridia,3XZNB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
NGKEMLHH_02692	457412.RSAG_01490	2.57e-164	478.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
NGKEMLHH_02693	457412.RSAG_01489	3.22e-289	789.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
NGKEMLHH_02694	33035.JPJF01000035_gene3477	8.52e-179	502.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AHK@186801|Clostridia,3XZH7@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_02695	33035.JPJF01000035_gene3478	3.15e-233	650.0	COG1653@1|root,COG1653@2|Bacteria,1UZFS@1239|Firmicutes	1239|Firmicutes	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_02696	1121115.AXVN01000022_gene1746	1.21e-281	774.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,3XZD8@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
NGKEMLHH_02697	457412.RSAG_02149	1.16e-210	583.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,3WGVA@541000|Ruminococcaceae	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
NGKEMLHH_02698	1121115.AXVN01000019_gene160	1.79e-104	310.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,3XZY8@572511|Blautia	186801|Clostridia	GM	Psort location Cytoplasmic, score 8.87	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
NGKEMLHH_02699	478749.BRYFOR_09281	1.62e-84	259.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24G4J@186801|Clostridia	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
NGKEMLHH_02700	478749.BRYFOR_09282	2.55e-86	265.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia	186801|Clostridia	D	Capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
NGKEMLHH_02701	457412.RSAG_02570	7.44e-169	471.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,3WIW2@541000|Ruminococcaceae	186801|Clostridia	E	PHP domain protein	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
NGKEMLHH_02702	457412.RSAG_03510	2.27e-103	298.0	COG4154@1|root,COG4154@2|Bacteria,1V402@1239|Firmicutes,24FU7@186801|Clostridia,3WJ3H@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the RbsD FucU family	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
NGKEMLHH_02703	457412.RSAG_01763	0.0	1230.0	COG2407@1|root,COG2407@2|Bacteria,1TQ5Q@1239|Firmicutes,248V0@186801|Clostridia,3WHBE@541000|Ruminococcaceae	186801|Clostridia	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
NGKEMLHH_02704	1121115.AXVN01000086_gene4016	8.53e-211	581.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V1UE@1239|Firmicutes,24AK4@186801|Clostridia,3XZ87@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NGKEMLHH_02705	457412.RSAG_01765	1.38e-221	615.0	COG2096@1|root,COG3193@1|root,COG2096@2|Bacteria,COG3193@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia,3WPYX@541000|Ruminococcaceae	186801|Clostridia	S	Haem-degrading	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,Haem_degrading
NGKEMLHH_02706	1121115.AXVN01000086_gene4014	1.97e-276	756.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XZNH@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NGKEMLHH_02707	1121115.AXVN01000086_gene4013	1.27e-173	485.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia,3XZ48@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
NGKEMLHH_02708	1121115.AXVN01000086_gene4012	6.28e-118	338.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,3XZUS@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	csoS1C	-	-	-	-	-	-	-	-	-	-	-	BMC
NGKEMLHH_02709	1121115.AXVN01000086_gene4011	0.0	869.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XZ7S@572511|Blautia	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase 51 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
NGKEMLHH_02710	1121115.AXVN01000086_gene4010	9.07e-52	164.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,3Y0FT@572511|Blautia	186801|Clostridia	CQ	COG COG4576 Carbon dioxide concentrating mechanism carboxysome shell protein	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
NGKEMLHH_02711	457412.RSAG_01771	2.7e-146	412.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,3WJCD@541000|Ruminococcaceae	186801|Clostridia	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	pduL	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTAC
NGKEMLHH_02712	1121115.AXVN01000086_gene4008	1.22e-69	214.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NGKEMLHH_02713	1121115.AXVN01000086_gene4007	1.77e-62	191.0	COG4577@1|root,COG4577@2|Bacteria,1V9YU@1239|Firmicutes,24MUN@186801|Clostridia,3Y0DW@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NGKEMLHH_02714	1121115.AXVN01000086_gene4006	7.33e-51	161.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NGKEMLHH_02715	1121115.AXVN01000086_gene4005	2.19e-67	204.0	2CTB7@1|root,32ST1@2|Bacteria,1UPS8@1239|Firmicutes,25HN2@186801|Clostridia	186801|Clostridia	S	BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NGKEMLHH_02716	1121115.AXVN01000004_gene1976	0.0	899.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NGKEMLHH_02717	1121115.AXVN01000098_gene2879	9.44e-224	619.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,24AF9@186801|Clostridia	186801|Clostridia	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
NGKEMLHH_02718	457412.RSAG_01932	1.04e-189	528.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3WH9Z@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
NGKEMLHH_02719	457412.RSAG_00907	1.28e-205	570.0	COG0679@1|root,COG0679@2|Bacteria,1TRAI@1239|Firmicutes,24HU9@186801|Clostridia,3WPNA@541000|Ruminococcaceae	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NGKEMLHH_02720	457412.RSAG_00908	6.21e-214	592.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,3WI1Q@541000|Ruminococcaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NGKEMLHH_02721	1121115.AXVN01000104_gene846	0.0	1071.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,3Y116@572511|Blautia	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
NGKEMLHH_02722	1121115.AXVN01000104_gene847	5.17e-91	275.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3Y143@572511|Blautia	186801|Clostridia	H	Phosphoadenosine phosphosulfate reductase family	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
NGKEMLHH_02723	1121115.AXVN01000037_gene3246	2.88e-17	75.9	COG0346@1|root,COG0346@2|Bacteria,1V7XP@1239|Firmicutes,24KYI@186801|Clostridia,3Y0HK@572511|Blautia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
NGKEMLHH_02724	1121115.AXVN01000037_gene3247	0.0	1068.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3XYQY@572511|Blautia	186801|Clostridia	G	Mannitol dehydrogenase Rossmann domain	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
NGKEMLHH_02725	411459.RUMOBE_02431	0.0	884.0	COG3534@1|root,COG3534@2|Bacteria,1TPJ0@1239|Firmicutes,25EH6@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
NGKEMLHH_02726	411459.RUMOBE_02433	5e-167	467.0	COG3279@1|root,COG3279@2|Bacteria,1UVFF@1239|Firmicutes,25KHB@186801|Clostridia,3Y15T@572511|Blautia	186801|Clostridia	KT	COG COG3279 Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NGKEMLHH_02728	1232452.BAIB02000005_gene656	1.27e-18	89.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,269JD@186813|unclassified Clostridiales	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NGKEMLHH_02730	397291.C804_05690	1.07e-17	85.1	2DBKH@1|root,2Z9T5@2|Bacteria,1TQWZ@1239|Firmicutes,24D49@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NGKEMLHH_02731	397291.C804_05689	2.03e-99	293.0	2E7UB@1|root,3329C@2|Bacteria,1VHFQ@1239|Firmicutes,24SM4@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02733	658086.HMPREF0994_01877	1.11e-41	154.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,27IGE@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ABC transporter C-terminal domain	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NGKEMLHH_02734	457412.RSAG_01456	4.41e-185	522.0	COG1757@1|root,COG1757@2|Bacteria,1TQPI@1239|Firmicutes,2495U@186801|Clostridia,3WGEF@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	mleN_2	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
NGKEMLHH_02735	1121115.AXVN01000069_gene2319	1.49e-138	393.0	COG0789@1|root,COG0789@2|Bacteria,1V53F@1239|Firmicutes,24IQ8@186801|Clostridia,3Y2B8@572511|Blautia	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NGKEMLHH_02736	1121115.AXVN01000069_gene2320	1.61e-64	197.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,3Y0P1@572511|Blautia	186801|Clostridia	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
NGKEMLHH_02737	1121115.AXVN01000038_gene3344	1.57e-172	480.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,3XYMH@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	ulaF	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
NGKEMLHH_02738	1121115.AXVN01000038_gene3345	4.09e-220	608.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,25D2S@186801|Clostridia,3Y1VG@572511|Blautia	186801|Clostridia	K	Putative sugar-binding domain	sorC	-	-	-	-	-	-	-	-	-	-	-	HTH_24,Sugar-bind
NGKEMLHH_02739	457412.RSAG_02307	3.95e-55	173.0	2BQ4H@1|root,32IYV@2|Bacteria,1US27@1239|Firmicutes,25A0K@186801|Clostridia,3WQZK@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02740	1121115.AXVN01000021_gene1712	0.0	959.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3XYX4@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	speA_1	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
NGKEMLHH_02741	1121115.AXVN01000021_gene1713	1.6e-140	396.0	COG0194@1|root,COG0194@2|Bacteria,1V3RZ@1239|Firmicutes,24HKC@186801|Clostridia,3XZXN@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	gmk_1	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
NGKEMLHH_02742	457412.RSAG_03291	1.9e-233	642.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,3WI7S@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
NGKEMLHH_02743	1121115.AXVN01000021_gene1715	1.7e-205	569.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,3XYM3@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
NGKEMLHH_02744	1121115.AXVN01000021_gene1716	2.14e-177	494.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,3XZ60@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
NGKEMLHH_02745	1121115.AXVN01000021_gene1717	5.91e-198	549.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,3XYJ8@572511|Blautia	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
NGKEMLHH_02746	1121115.AXVN01000021_gene1718	0.0	1269.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,3XYYE@572511|Blautia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NGKEMLHH_02747	1121115.AXVN01000021_gene1719	0.0	1596.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,3XZN8@572511|Blautia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
NGKEMLHH_02748	1121115.AXVN01000021_gene1720	4.28e-131	372.0	2BWC2@1|root,33RSK@2|Bacteria,1VS2M@1239|Firmicutes,24YI2@186801|Clostridia,3Y093@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02749	457412.RSAG_03284	1.9e-171	478.0	COG0204@1|root,COG0204@2|Bacteria,1TTPK@1239|Firmicutes,24B6K@186801|Clostridia,3WIQF@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
NGKEMLHH_02751	180332.JTGN01000004_gene2620	2.09e-160	483.0	COG1609@1|root,COG1879@1|root,COG1609@2|Bacteria,COG1879@2|Bacteria,1TS5P@1239|Firmicutes,24E9X@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3,Peripla_BP_4
NGKEMLHH_02752	1002367.HMPREF0673_00077	2.79e-155	442.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,2FME1@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143,HTH_11
NGKEMLHH_02753	1002367.HMPREF0673_00077	9.55e-93	280.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,2FME1@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143,HTH_11
NGKEMLHH_02754	1121115.AXVN01000020_gene108	7.46e-258	707.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,3XYHX@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	xerS	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
NGKEMLHH_02755	1121115.AXVN01000020_gene107	2.17e-56	175.0	2E0EA@1|root,32W0W@2|Bacteria,1VB0V@1239|Firmicutes,24R8X@186801|Clostridia,3Y20U@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02756	1121115.AXVN01000020_gene106	1.7e-92	270.0	COG0433@1|root,COG0433@2|Bacteria,1VF8X@1239|Firmicutes,24N9T@186801|Clostridia,3Y046@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02757	1121115.AXVN01000023_gene1786	0.0	1100.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,3XZEM@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
NGKEMLHH_02758	1121115.AXVN01000023_gene1787	9.1e-54	168.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,3Y0NQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
NGKEMLHH_02759	457412.RSAG_02588	4.9e-81	242.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NGKEMLHH_02760	1121115.AXVN01000157_gene539	0.0	1169.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3XZ6T@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
NGKEMLHH_02761	742733.HMPREF9469_05568	0.0	1165.0	COG0582@1|root,COG0582@2|Bacteria,1TQQ1@1239|Firmicutes,24BI9@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
NGKEMLHH_02762	1196322.A370_05736	2.92e-28	121.0	COG1475@1|root,COG1475@2|Bacteria,1V8BD@1239|Firmicutes,24DI5@186801|Clostridia,36FVI@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	DUF3850,ParBc
NGKEMLHH_02763	1280706.AUJE01000010_gene635	7.84e-33	127.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4H4ZY@909932|Negativicutes	909932|Negativicutes	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NGKEMLHH_02764	457424.BFAG_01722	4.94e-141	399.0	2EGCM@1|root,33A4E@2|Bacteria,4NY23@976|Bacteroidetes,2FQIZ@200643|Bacteroidia	976|Bacteroidetes	S	RloB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	RloB
NGKEMLHH_02765	457424.BFAG_01723	5.52e-285	781.0	COG1106@1|root,COG1106@2|Bacteria,4NE5J@976|Bacteroidetes,2FQDP@200643|Bacteroidia,4AP53@815|Bacteroidaceae	976|Bacteroidetes	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
NGKEMLHH_02766	742765.HMPREF9457_02461	3.72e-78	233.0	2C5R4@1|root,32VWV@2|Bacteria,1VC7E@1239|Firmicutes,24MW9@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NGKEMLHH_02767	742765.HMPREF9457_02460	9.25e-51	173.0	28HPA@1|root,2Z7XB@2|Bacteria,1TRBX@1239|Firmicutes,24AUG@186801|Clostridia,27W3E@189330|Dorea	186801|Clostridia	S	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NGKEMLHH_02768	742765.HMPREF9457_02460	1.21e-76	244.0	28HPA@1|root,2Z7XB@2|Bacteria,1TRBX@1239|Firmicutes,24AUG@186801|Clostridia,27W3E@189330|Dorea	186801|Clostridia	S	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NGKEMLHH_02769	1121115.AXVN01000067_gene3464	5.52e-34	117.0	2E9U2@1|root,303KU@2|Bacteria,1TUSU@1239|Firmicutes,258EM@186801|Clostridia,3Y24U@572511|Blautia	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
NGKEMLHH_02770	1297617.JPJD01000094_gene2517	4.15e-42	138.0	2AF2F@1|root,3150Z@2|Bacteria,1V73X@1239|Firmicutes,24K1N@186801|Clostridia,26C8M@186813|unclassified Clostridiales	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NGKEMLHH_02771	500632.CLONEX_04241	3.47e-35	132.0	COG3039@1|root,COG3039@2|Bacteria,1TRUS@1239|Firmicutes,24AH8@186801|Clostridia	186801|Clostridia	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
NGKEMLHH_02772	397290.C810_01428	2.14e-99	300.0	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,248VD@186801|Clostridia,27K2N@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NGKEMLHH_02773	1121115.AXVN01000168_gene723	1.56e-09	63.9	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3Y1RC@572511|Blautia	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
NGKEMLHH_02774	457412.RSAG_01746	0.0	1583.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,3WGEC@541000|Ruminococcaceae	186801|Clostridia	L	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
NGKEMLHH_02775	1121115.AXVN01000118_gene3311	5.85e-313	858.0	COG2367@1|root,COG2367@2|Bacteria,1V6K6@1239|Firmicutes,24KPP@186801|Clostridia,3Y01V@572511|Blautia	186801|Clostridia	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
NGKEMLHH_02776	1121115.AXVN01000118_gene3310	2.42e-300	820.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25AGX@186801|Clostridia,3XZXG@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH_2
NGKEMLHH_02777	1121115.AXVN01000118_gene3309	7.92e-113	323.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,3XZW5@572511|Blautia	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
NGKEMLHH_02778	1121115.AXVN01000118_gene3308	0.0	922.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3XZA4@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
NGKEMLHH_02779	457412.RSAG_01741	2.48e-106	307.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,3WJN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
NGKEMLHH_02780	1121115.AXVN01000118_gene3306	5.22e-173	483.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3XZ93@572511|Blautia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
NGKEMLHH_02781	1121115.AXVN01000118_gene3305	3.32e-135	383.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia,3XZYB@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
NGKEMLHH_02782	1121115.AXVN01000008_gene2675	3.27e-206	572.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZG8@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NGKEMLHH_02783	457412.RSAG_02546	7.99e-194	539.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WIY9@541000|Ruminococcaceae	186801|Clostridia	P	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
NGKEMLHH_02784	411459.RUMOBE_00578	1.43e-73	220.0	2BPCF@1|root,32I4G@2|Bacteria,1V6FP@1239|Firmicutes,24MGG@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02785	411459.RUMOBE_00577	2.5e-81	241.0	COG1396@1|root,COG1396@2|Bacteria,1UVF5@1239|Firmicutes,25KH6@186801|Clostridia,3Y27G@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02786	411459.RUMOBE_00575	2.18e-91	268.0	COG1191@1|root,COG1191@2|Bacteria,1UJZK@1239|Firmicutes,25FFS@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
NGKEMLHH_02787	411459.RUMOBE_00574	1.6e-49	157.0	2AJW5@1|root,31AIZ@2|Bacteria,1V7QN@1239|Firmicutes,24JQH@186801|Clostridia,3Y271@572511|Blautia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NGKEMLHH_02789	397288.C806_02995	3.07e-143	422.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,27K85@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
NGKEMLHH_02790	1235793.C809_01687	2.37e-25	94.0	2CDEH@1|root,32YRT@2|Bacteria,1VFMR@1239|Firmicutes,24QUE@186801|Clostridia,27PJJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Maff2 family	-	-	-	-	-	-	-	-	-	-	-	-	Maff2
NGKEMLHH_02791	411483.FAEPRAA2165_03208	1.62e-64	197.0	COG1695@1|root,COG1695@2|Bacteria,1V9XX@1239|Firmicutes,24RE5@186801|Clostridia,3WK2V@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
NGKEMLHH_02792	411483.FAEPRAA2165_03209	3.13e-115	332.0	28M4E@1|root,2ZAIC@2|Bacteria,1UYVC@1239|Firmicutes,24I7N@186801|Clostridia,3WP5J@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2812)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2812
NGKEMLHH_02793	205914.HS_1528	3.13e-43	143.0	2DPES@1|root,331SN@2|Bacteria,1N8Q7@1224|Proteobacteria,1SGJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02794	457412.RSAG_00426	0.0	1018.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3WGYV@541000|Ruminococcaceae	186801|Clostridia	G	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
NGKEMLHH_02795	1121115.AXVN01000004_gene1989	6.67e-43	139.0	2CIA0@1|root,341N9@2|Bacteria,1VY7T@1239|Firmicutes,251RU@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2500
NGKEMLHH_02796	411459.RUMOBE_02367	1.73e-181	515.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,3XZPU@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_02797	1121115.AXVN01000017_gene265	0.0	1419.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia,3Y19B@572511|Blautia	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NGKEMLHH_02798	742742.HMPREF9452_00648	1.51e-102	300.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	capG	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
NGKEMLHH_02799	742742.HMPREF9452_00649	1.59e-190	533.0	28PSK@1|root,2ZCE3@2|Bacteria,2IBFI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02800	742742.HMPREF9452_00650	1.45e-53	180.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	lpg2	-	2.4.1.337	ko:K00754,ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
NGKEMLHH_02802	1121115.AXVN01000027_gene575	1.96e-85	258.0	28K00@1|root,2Z9Q0@2|Bacteria,1TR6B@1239|Firmicutes,24EVF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02805	1121115.AXVN01000016_gene3647	2.76e-192	543.0	COG1589@1|root,COG1589@2|Bacteria,1V34X@1239|Firmicutes,248RF@186801|Clostridia,3XZP0@572511|Blautia	186801|Clostridia	M	COG1589 Cell division septal protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
NGKEMLHH_02806	457412.RSAG_02392	6.85e-313	852.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WG8Y@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA2	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
NGKEMLHH_02807	457412.RSAG_02391	4.12e-253	695.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NGKEMLHH_02808	1121115.AXVN01000016_gene3650	0.0	897.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3XYZG@572511|Blautia	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
NGKEMLHH_02809	1121115.AXVN01000016_gene3651	4.74e-217	600.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3XZ7U@572511|Blautia	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
NGKEMLHH_02810	457412.RSAG_02388	0.0	1172.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WGI4@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
NGKEMLHH_02811	457412.RSAG_02387	0.0	1368.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WI1C@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein dimerisation domain	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
NGKEMLHH_02812	1121115.AXVN01000016_gene3654	9.16e-125	356.0	2E3U8@1|root,32YRK@2|Bacteria,1VEYB@1239|Firmicutes,24QRX@186801|Clostridia,3Y079@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
NGKEMLHH_02813	1121115.AXVN01000016_gene3655	1.55e-223	616.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3XYP8@572511|Blautia	186801|Clostridia	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
NGKEMLHH_02814	457412.RSAG_02384	2.79e-102	295.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,3WJCZ@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
NGKEMLHH_02815	457412.RSAG_02383	5.32e-242	665.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,3WH7A@541000|Ruminococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
NGKEMLHH_02816	1121115.AXVN01000016_gene3658	5.7e-260	712.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3XZ6D@572511|Blautia	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
NGKEMLHH_02817	411459.RUMOBE_02486	9.65e-143	402.0	28NMC@1|root,2ZA4G@2|Bacteria,1UYCN@1239|Firmicutes,24ACB@186801|Clostridia,3Y0IX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02818	1121115.AXVN01000016_gene3660	1.16e-220	629.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XYUA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NGKEMLHH_02819	1121115.AXVN01000016_gene3660	0.0	1212.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XYUA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NGKEMLHH_02820	1121115.AXVN01000016_gene3661	0.0	1853.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3XZIP@572511|Blautia	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NGKEMLHH_02821	1121115.AXVN01000016_gene3662	7.52e-289	792.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,2494S@186801|Clostridia,3XZ44@572511|Blautia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NGKEMLHH_02822	1121115.AXVN01000022_gene1757	3.85e-90	274.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia	186801|Clostridia	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,RicinB_lectin_2
NGKEMLHH_02824	1121115.AXVN01000022_gene1756	0.0	943.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XYXC@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
NGKEMLHH_02825	457412.RSAG_02157	6.22e-215	594.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia,3WJJR@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
NGKEMLHH_02826	457412.RSAG_02156	0.0	1481.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WH2S@541000|Ruminococcaceae	186801|Clostridia	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
NGKEMLHH_02827	1121115.AXVN01000022_gene1753	9.69e-316	859.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,3XZEH@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 9.36	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
NGKEMLHH_02828	1121115.AXVN01000022_gene1752	7.72e-194	538.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,3XZ2V@572511|Blautia	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
NGKEMLHH_02829	457412.RSAG_02153	7.9e-116	333.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,3WJC2@541000|Ruminococcaceae	186801|Clostridia	S	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
NGKEMLHH_02830	457412.RSAG_02152	6.83e-224	616.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WGEP@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
NGKEMLHH_02831	457412.RSAG_02151	4.64e-229	631.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,3WH6N@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
NGKEMLHH_02832	457412.RSAG_02150	1.5e-16	74.7	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3WKKU@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
NGKEMLHH_02833	1121115.AXVN01000003_gene1636	0.0	1006.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,249HE@186801|Clostridia,3XZ8V@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
NGKEMLHH_02834	1121115.AXVN01000003_gene1635	1.34e-174	486.0	COG0500@1|root,COG0500@2|Bacteria,1UKI1@1239|Firmicutes,25FXJ@186801|Clostridia	186801|Clostridia	Q	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	-	-	-	-	-	-	-	-	-	-	SAM_MT
NGKEMLHH_02837	272563.CD630_33310	2.32e-169	472.0	28IFW@1|root,2Z8HG@2|Bacteria,1UNS6@1239|Firmicutes,24AB6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CBAH
NGKEMLHH_02838	272563.CD630_33300	5.03e-75	224.0	COG1396@1|root,COG1396@2|Bacteria,1V50Y@1239|Firmicutes,24I1Y@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_02839	457412.RSAG_00152	2.85e-70	212.0	2E82Y@1|root,332GY@2|Bacteria,1VEU7@1239|Firmicutes,24P37@186801|Clostridia,3WQMH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02840	457412.RSAG_04644	2.7e-138	392.0	COG2339@1|root,COG2339@2|Bacteria,1V3JI@1239|Firmicutes,24AZQ@186801|Clostridia,3WIYQ@541000|Ruminococcaceae	186801|Clostridia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
NGKEMLHH_02841	1121115.AXVN01000037_gene3263	1.18e-55	173.0	2EC1A@1|root,3360H@2|Bacteria,1VHMT@1239|Firmicutes,24S6Y@186801|Clostridia,3Y1SK@572511|Blautia	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
NGKEMLHH_02842	1121115.AXVN01000037_gene3262	3.71e-91	267.0	2BAXA@1|root,324CZ@2|Bacteria,1UQP9@1239|Firmicutes,258FM@186801|Clostridia,3Y1K7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02843	457412.RSAG_04512	1.81e-172	482.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6A@186801|Clostridia,3WIKS@541000|Ruminococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
NGKEMLHH_02844	1121115.AXVN01000037_gene3260	1.25e-56	176.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3Y1RW@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
NGKEMLHH_02845	1121115.AXVN01000035_gene3823	8.57e-137	390.0	COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,24AY1@186801|Clostridia,3Y1HG@572511|Blautia	186801|Clostridia	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
NGKEMLHH_02846	457412.RSAG_02966	0.0	869.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WNWQ@541000|Ruminococcaceae	186801|Clostridia	V	MviN-like protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_02847	457412.RSAG_00247	4.52e-316	862.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_02848	1121115.AXVN01000017_gene264	5.86e-70	214.0	2BBFY@1|root,324Z7@2|Bacteria,1UR44@1239|Firmicutes,258XU@186801|Clostridia,3Y266@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02849	742765.HMPREF9457_03057	2.04e-191	534.0	COG1502@1|root,COG1502@2|Bacteria,1TRJE@1239|Firmicutes,248ZE@186801|Clostridia,27WDZ@189330|Dorea	186801|Clostridia	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
NGKEMLHH_02850	457412.RSAG_02746	1.76e-195	542.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NGKEMLHH_02851	1121115.AXVN01000012_gene3107	4.19e-152	439.0	COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,2497J@186801|Clostridia,3Y1AY@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
NGKEMLHH_02852	411459.RUMOBE_00621	8.11e-99	287.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,25BG6@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
NGKEMLHH_02853	1235792.C808_04781	9.36e-10	54.3	2CEPR@1|root,2ZSJ9@2|Bacteria,1W4DB@1239|Firmicutes,24USC@186801|Clostridia,27QGV@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02855	411470.RUMGNA_00900	4.51e-27	103.0	2DMY9@1|root,32UCT@2|Bacteria,1VAN7@1239|Firmicutes,24PHY@186801|Clostridia,3Y1J6@572511|Blautia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NGKEMLHH_02856	1121115.AXVN01000054_gene1876	2.82e-197	546.0	COG3279@1|root,COG3279@2|Bacteria,1UVR7@1239|Firmicutes,25KKV@186801|Clostridia,3Y27H@572511|Blautia	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NGKEMLHH_02857	457412.RSAG_02718	1.75e-147	420.0	2EZ41@1|root,33SA8@2|Bacteria,1VSVN@1239|Firmicutes,24XVU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02858	457412.RSAG_02718	3.71e-34	125.0	2EZ41@1|root,33SA8@2|Bacteria,1VSVN@1239|Firmicutes,24XVU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02859	457412.RSAG_02719	9.56e-180	502.0	COG3290@1|root,COG3290@2|Bacteria,1VDUW@1239|Firmicutes,24QIG@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NGKEMLHH_02860	1121115.AXVN01000054_gene1873	6.26e-215	593.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24I3P@186801|Clostridia,3Y1VY@572511|Blautia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NGKEMLHH_02861	457412.RSAG_02721	0.0	1508.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WH1C@541000|Ruminococcaceae	186801|Clostridia	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP_1	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
NGKEMLHH_02862	1121115.AXVN01000054_gene1871	4.48e-299	815.0	29WP9@1|root,30IA6@2|Bacteria,1V4GZ@1239|Firmicutes,24HWX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02863	457412.RSAG_02723	7.52e-158	442.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3WGWR@541000|Ruminococcaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
NGKEMLHH_02864	1121115.AXVN01000090_gene2558	1.37e-64	196.0	2E7YJ@1|root,30FFS@2|Bacteria,1UDZU@1239|Firmicutes,25IU2@186801|Clostridia,3Y1VR@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02865	457412.RSAG_02725	1.52e-197	546.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,3WGHY@541000|Ruminococcaceae	186801|Clostridia	L	8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
NGKEMLHH_02866	1121115.AXVN01000090_gene2560	2.83e-62	190.0	COG1598@1|root,COG1598@2|Bacteria,1VH8E@1239|Firmicutes,2586D@186801|Clostridia,3Y0CI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
NGKEMLHH_02868	411473.RUMCAL_02480	1.54e-26	101.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24JVC@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NGKEMLHH_02869	658086.HMPREF0994_04272	3.49e-191	532.0	COG0395@1|root,COG0395@2|Bacteria,1TQ9F@1239|Firmicutes,24XSB@186801|Clostridia	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_02870	1232449.BAHV02000002_gene87	1.26e-154	453.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,267PN@186813|unclassified Clostridiales	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NGKEMLHH_02871	457412.RSAG_00730	2.07e-284	776.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WHD5@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
NGKEMLHH_02872	457412.RSAG_00729	1.5e-115	330.0	COG0454@1|root,COG0456@2|Bacteria,1V6Z8@1239|Firmicutes,24JT6@186801|Clostridia,3WSRJ@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NGKEMLHH_02873	1121115.AXVN01000006_gene2110	1.26e-70	224.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,3XZRA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
NGKEMLHH_02874	1121115.AXVN01000001_gene1049	1.42e-230	644.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3XZ8D@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
NGKEMLHH_02875	457412.RSAG_02969	1.02e-187	525.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJ00@541000|Ruminococcaceae	186801|Clostridia	L	transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
NGKEMLHH_02876	1121115.AXVN01000026_gene1014	1.45e-43	145.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3Y18S@572511|Blautia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
NGKEMLHH_02877	457412.RSAG_02967	2.74e-96	280.0	COG1943@1|root,COG1943@2|Bacteria,1V3YY@1239|Firmicutes,24IB0@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS200-family protein	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
NGKEMLHH_02878	1121115.AXVN01000021_gene1680	2.69e-166	470.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia,3XZ0E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
NGKEMLHH_02879	1121115.AXVN01000021_gene1681	5.61e-231	640.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3XYK5@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
NGKEMLHH_02880	411459.RUMOBE_01990	1.47e-132	379.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,3XYJP@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_02881	1121115.AXVN01000027_gene587	1.82e-110	319.0	COG2105@1|root,COG2105@2|Bacteria,1VGQA@1239|Firmicutes,24N69@186801|Clostridia,3Y0SW@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4314
NGKEMLHH_02882	1121115.AXVN01000027_gene586	3.5e-168	471.0	28VH4@1|root,2ZHJM@2|Bacteria,1W2SJ@1239|Firmicutes,25511@186801|Clostridia,3Y20Y@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02883	457412.RSAG_00256	0.0	1443.0	COG4096@1|root,COG4096@2|Bacteria,1UI7V@1239|Firmicutes,25ED3@186801|Clostridia,3WGBZ@541000|Ruminococcaceae	186801|Clostridia	L	EcoEI R protein C-terminal	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
NGKEMLHH_02884	457412.RSAG_00900	0.0	1204.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3WSRM@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
NGKEMLHH_02885	1121115.AXVN01000012_gene3117	0.0	1058.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia,3Y0TG@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
NGKEMLHH_02886	1121115.AXVN01000002_gene1452	3.2e-83	246.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3Y05K@572511|Blautia	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
NGKEMLHH_02887	1121115.AXVN01000002_gene1451	0.0	1148.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,3XZH5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
NGKEMLHH_02888	1121115.AXVN01000002_gene1450	1.12e-55	180.0	29V65@1|root,30GJT@2|Bacteria,1UG71@1239|Firmicutes,25NFM@186801|Clostridia,3Y24B@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02889	457412.RSAG_00087	2.06e-258	709.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WIY7@541000|Ruminococcaceae	186801|Clostridia	J	Metallo-beta-lactamase domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
NGKEMLHH_02890	1121115.AXVN01000002_gene1448	7.15e-122	348.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,3Y071@572511|Blautia	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
NGKEMLHH_02891	1121115.AXVN01000002_gene1447	0.0	919.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3XZ69@572511|Blautia	186801|Clostridia	H	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
NGKEMLHH_02892	1121115.AXVN01000002_gene1446	7.25e-26	105.0	COG1680@1|root,COG1680@2|Bacteria,1W747@1239|Firmicutes,256Q7@186801|Clostridia,3Y0WX@572511|Blautia	2|Bacteria	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
NGKEMLHH_02893	1121115.AXVN01000002_gene1446	0.0	1086.0	COG1680@1|root,COG1680@2|Bacteria,1W747@1239|Firmicutes,256Q7@186801|Clostridia,3Y0WX@572511|Blautia	2|Bacteria	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
NGKEMLHH_02894	457412.RSAG_00083	3.51e-309	843.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NGKEMLHH_02895	1443125.Z962_00255	1.91e-10	68.2	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,36KH6@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
NGKEMLHH_02896	1235799.C818_03392	1.47e-43	142.0	2DZZU@1|root,32VPB@2|Bacteria,1VB1I@1239|Firmicutes,24PDU@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02897	537007.BLAHAN_06450	6.57e-288	789.0	COG3378@1|root,COG3378@2|Bacteria,1TSGZ@1239|Firmicutes,24CI8@186801|Clostridia,3Y0RF@572511|Blautia	186801|Clostridia	S	Phage plasmid primase, P4 family domain protein	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5
NGKEMLHH_02898	457412.RSAG_03271	2.14e-240	660.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia,3WJKX@541000|Ruminococcaceae	186801|Clostridia	S	Spore coat protein, CotS family	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
NGKEMLHH_02899	1121115.AXVN01000099_gene778	1.6e-55	174.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3Y0HQ@572511|Blautia	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
NGKEMLHH_02900	1121115.AXVN01000099_gene779	3.38e-46	149.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,3Y0D7@572511|Blautia	186801|Clostridia	J	COG COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
NGKEMLHH_02902	457412.RSAG_00600	7.21e-236	647.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,249GM@186801|Clostridia,3WGAM@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
NGKEMLHH_02903	1121115.AXVN01000003_gene1582	7.28e-171	483.0	COG1820@1|root,COG1820@2|Bacteria,1UK3V@1239|Firmicutes,25FIQ@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation	iadA	-	-	ko:K01305	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Amidohydro_1,Amidohydro_3
NGKEMLHH_02904	748224.HMPREF9436_01274	1.1e-37	139.0	COG3279@1|root,COG3279@2|Bacteria,1UYHU@1239|Firmicutes,24CBK@186801|Clostridia,3WRIR@541000|Ruminococcaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NGKEMLHH_02905	1235790.C805_01089	8.82e-31	130.0	COG3290@1|root,COG3290@2|Bacteria,1UZ59@1239|Firmicutes,24A0V@186801|Clostridia,25ZX9@186806|Eubacteriaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NGKEMLHH_02906	1121115.AXVN01000003_gene1583	0.0	962.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia	186801|Clostridia	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
NGKEMLHH_02907	1121115.AXVN01000081_gene3051	0.0	949.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3XYNN@572511|Blautia	186801|Clostridia	H	FGGY family of carbohydrate kinases, C-terminal domain	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
NGKEMLHH_02908	1121115.AXVN01000123_gene2866	1.61e-254	699.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,3XZPW@572511|Blautia	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
NGKEMLHH_02909	1121115.AXVN01000100_gene829	9.06e-260	710.0	COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,24AY7@186801|Clostridia,3XYJG@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N,ADH_zinc_N_2
NGKEMLHH_02910	1121115.AXVN01000100_gene830	2.86e-93	272.0	COG1116@1|root,COG1116@2|Bacteria,1VAD8@1239|Firmicutes,24GFE@186801|Clostridia,3Y1PX@572511|Blautia	186801|Clostridia	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NGKEMLHH_02911	1121115.AXVN01000003_gene1586	8.06e-116	336.0	COG0600@1|root,COG0600@2|Bacteria,1V73W@1239|Firmicutes,24A2R@186801|Clostridia,3Y1BD@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
NGKEMLHH_02912	1121115.AXVN01000029_gene642	6.28e-68	220.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3XZHQ@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
NGKEMLHH_02913	1121115.AXVN01000029_gene641	9.82e-118	337.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,3XZ59@572511|Blautia	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
NGKEMLHH_02914	1121115.AXVN01000029_gene640	0.0	1503.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,3XZ3M@572511|Blautia	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
NGKEMLHH_02915	1121115.AXVN01000029_gene639	1.3e-155	436.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,3Y04N@572511|Blautia	186801|Clostridia	S	COG COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NGKEMLHH_02916	457412.RSAG_00516	0.0	996.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,3WGA8@541000|Ruminococcaceae	186801|Clostridia	C	Coproporphyrinogen dehydrogenase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NGKEMLHH_02917	457412.RSAG_00515	1.34e-158	444.0	COG2206@1|root,COG2206@2|Bacteria,1V54U@1239|Firmicutes,24HUA@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5
NGKEMLHH_02918	1121115.AXVN01000029_gene636	4.11e-293	800.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,3XYX1@572511|Blautia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
NGKEMLHH_02919	1121115.AXVN01000029_gene635	0.0	1172.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,3XZ1M@572511|Blautia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
NGKEMLHH_02920	1121115.AXVN01000029_gene634	4.08e-169	473.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia,3XZD6@572511|Blautia	186801|Clostridia	S	Sulfite exporter TauE/SafE	yfcA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
NGKEMLHH_02921	1121115.AXVN01000029_gene633	2.11e-272	747.0	2F32Z@1|root,33VY0@2|Bacteria,1VRWP@1239|Firmicutes,25PV9@186801|Clostridia,3XZBM@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02922	1121115.AXVN01000038_gene3332	8.51e-90	268.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia,3XZGR@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_02923	1121115.AXVN01000038_gene3333	0.0	1119.0	COG2972@1|root,COG2972@2|Bacteria,1UZWA@1239|Firmicutes,24EGG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
NGKEMLHH_02924	1121115.AXVN01000137_gene1820	6.21e-172	479.0	29XPW@1|root,30JFI@2|Bacteria,1TTS7@1239|Firmicutes,257QZ@186801|Clostridia,3Y1YX@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
NGKEMLHH_02926	411459.RUMOBE_01639	3.58e-66	208.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3XZ0D@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NGKEMLHH_02927	411459.RUMOBE_01639	2.29e-121	352.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3XZ0D@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NGKEMLHH_02928	411459.RUMOBE_01638	8.54e-97	293.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3XZ7P@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
NGKEMLHH_02929	697329.Rumal_3440	7.24e-122	373.0	2F7EH@1|root,33ZVC@2|Bacteria,1VY5X@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02930	457412.RSAG_00274	7.15e-176	490.0	COG5551@1|root,COG5551@2|Bacteria,1V7VJ@1239|Firmicutes,24IY3@186801|Clostridia,3WKX0@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR-associated endoribonuclease Cas6	cas6	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
NGKEMLHH_02931	1280671.AUJH01000042_gene1121	0.0	894.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,4BXCY@830|Butyrivibrio	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_02933	1121098.HMPREF1534_02560	1.25e-249	685.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,2FNFV@200643|Bacteroidia,4AMGQ@815|Bacteroidaceae	976|Bacteroidetes	G	F5 8 type C domain protein	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
NGKEMLHH_02934	1235798.C817_03206	1.58e-122	354.0	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,27W0B@189330|Dorea	186801|Clostridia	K	AraC-like ligand binding domain	araC_2	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
NGKEMLHH_02935	658655.HMPREF0988_00623	2.96e-284	778.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,27KKZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
NGKEMLHH_02936	397288.C806_00891	7.44e-140	415.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27J46@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_02937	1121333.JMLH01000033_gene2895	0.0	932.0	COG4932@1|root,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,3VP4C@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02938	1280698.AUJS01000017_gene1789	3.05e-19	78.6	2E62Q@1|root,330RT@2|Bacteria,1VIVX@1239|Firmicutes,255Z5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02939	1232447.BAHW02000027_gene2092	1.86e-228	633.0	28PM6@1|root,2Z8J4@2|Bacteria,1UXZE@1239|Firmicutes,24B7N@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02940	1280698.AUJS01000017_gene1791	2.4e-59	184.0	29529@1|root,2ZSF2@2|Bacteria,1W1UD@1239|Firmicutes,254SW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02941	1121333.JMLH01000033_gene2892	0.0	4648.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,3VNX4@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
NGKEMLHH_02943	742765.HMPREF9457_02910	1.32e-228	633.0	COG5002@1|root,COG5002@2|Bacteria,1UHZU@1239|Firmicutes,25E8I@186801|Clostridia,27VY8@189330|Dorea	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NGKEMLHH_02944	483218.BACPEC_00657	6.3e-151	425.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,26A9M@186813|unclassified Clostridiales	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_02945	1121115.AXVN01000001_gene1094	3.48e-159	450.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3XZT9@572511|Blautia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
NGKEMLHH_02946	1121115.AXVN01000001_gene1093	1.99e-285	780.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3XYJM@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
NGKEMLHH_02947	908340.HMPREF9406_0546	1.58e-82	260.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,36GFC@31979|Clostridiaceae	186801|Clostridia	L	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zf-ribbon_3,zinc_ribbon_2
NGKEMLHH_02948	537013.CLOSTMETH_02269	5.18e-29	109.0	COG2314@1|root,COG2314@2|Bacteria,1VNA3@1239|Firmicutes,24UCG@186801|Clostridia,3WMHZ@541000|Ruminococcaceae	186801|Clostridia	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
NGKEMLHH_02949	658655.HMPREF0988_02359	1.84e-45	147.0	2FHZN@1|root,349SK@2|Bacteria,1TVGM@1239|Firmicutes,25AT8@186801|Clostridia,27QJ2@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02951	742765.HMPREF9457_02930	6.42e-233	648.0	COG1653@1|root,COG1653@2|Bacteria,1UVGF@1239|Firmicutes,25MFW@186801|Clostridia,27WU0@189330|Dorea	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NGKEMLHH_02952	457412.RSAG_01024	1.85e-147	426.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia,3WHG7@541000|Ruminococcaceae	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
NGKEMLHH_02953	1121115.AXVN01000155_gene550	4.97e-177	493.0	COG1051@1|root,COG1051@2|Bacteria,1VD3G@1239|Firmicutes,25MXE@186801|Clostridia,3Y20J@572511|Blautia	186801|Clostridia	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
NGKEMLHH_02954	1121115.AXVN01000155_gene549	3.19e-66	201.0	296J0@1|root,2ZTUJ@2|Bacteria,1V3IP@1239|Firmicutes,24H9K@186801|Clostridia	186801|Clostridia	S	Bacterial mobilization protein MobC	-	-	-	-	-	-	-	-	-	-	-	-	MobC
NGKEMLHH_02955	1121333.JMLH01000050_gene625	5.42e-26	105.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,3VNWF@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NGKEMLHH_02956	1410628.JNKS01000056_gene562	1.71e-49	158.0	COG2963@1|root,COG2963@2|Bacteria,1VHFV@1239|Firmicutes,25BV6@186801|Clostridia,27TEF@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
NGKEMLHH_02957	1410626.JHXB01000031_gene1709	2.65e-50	168.0	COG2801@1|root,COG2801@2|Bacteria,1TRUP@1239|Firmicutes,24AJD@186801|Clostridia,27KEC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
NGKEMLHH_02958	693746.OBV_29160	2.03e-66	212.0	COG2801@1|root,COG2801@2|Bacteria,1TRV8@1239|Firmicutes,24A6I@186801|Clostridia,2N7U4@216572|Oscillospiraceae	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
NGKEMLHH_02959	1410617.JHXH01000015_gene95	4.35e-34	119.0	COG2963@1|root,COG2963@2|Bacteria,1VC5D@1239|Firmicutes,24T2A@186801|Clostridia,3WS2S@541000|Ruminococcaceae	186801|Clostridia	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
NGKEMLHH_02960	469596.HMPREF9488_02221	4.62e-12	65.9	COG0358@1|root,COG0358@2|Bacteria,1TSIU@1239|Firmicutes,3VQJE@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Protein of unknown function (DUF3991)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3991,Toprim_2
NGKEMLHH_02961	457412.RSAG_00951	2.35e-206	570.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,3WGB9@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
NGKEMLHH_02962	1121115.AXVN01000002_gene1338	5.63e-89	261.0	2CJZW@1|root,30J0V@2|Bacteria,1UVFN@1239|Firmicutes,2596T@186801|Clostridia,3Y21H@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02963	1157708.KB907450_gene5270	1.2e-39	137.0	COG1786@1|root,COG1786@2|Bacteria,1RH5T@1224|Proteobacteria,2WG55@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
NGKEMLHH_02964	1532558.JL39_16620	1.49e-97	305.0	COG1679@1|root,COG1679@2|Bacteria,1NFH4@1224|Proteobacteria,2TTR6@28211|Alphaproteobacteria,4B9RE@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF126,DUF521
NGKEMLHH_02965	457412.RSAG_02597	0.0	1211.0	COG0426@1|root,COG1773@1|root,COG1853@1|root,COG0426@2|Bacteria,COG1773@2|Bacteria,COG1853@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
NGKEMLHH_02967	1123311.KB904489_gene1678	6.87e-22	86.3	2DQKF@1|root,337FN@2|Bacteria,1VN73@1239|Firmicutes,4HSEG@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02971	1158604.I591_02854	2.01e-49	163.0	COG2214@1|root,COG2214@2|Bacteria,1V7Z6@1239|Firmicutes,4HW1S@91061|Bacilli,4AZSE@81852|Enterococcaceae	91061|Bacilli	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
NGKEMLHH_02975	742738.HMPREF9460_03543	2.9e-110	332.0	28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,24GI2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Viral_Rep
NGKEMLHH_02976	1408306.JHXX01000005_gene1146	4.19e-130	388.0	COG1674@1|root,COG1674@2|Bacteria,1UYYW@1239|Firmicutes,24EN0@186801|Clostridia	186801|Clostridia	D	FtsK/SpoIIIE family	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
NGKEMLHH_02977	1408306.JHXX01000005_gene1147	2.54e-245	680.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,4BXJ9@830|Butyrivibrio	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_integrase
NGKEMLHH_02978	471875.RUMLAC_00021	2.03e-85	253.0	COG0073@1|root,COG0073@2|Bacteria,1V3A6@1239|Firmicutes,24GQK@186801|Clostridia,3WP6G@541000|Ruminococcaceae	186801|Clostridia	J	Putative tRNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_bind
NGKEMLHH_02979	1121115.AXVN01000017_gene235	1.5e-117	369.0	2EAGJ@1|root,334JU@2|Bacteria,1VH9K@1239|Firmicutes,24IKS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02980	1121115.AXVN01000017_gene234	8.08e-73	225.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	ppdA	-	-	ko:K02679,ko:K08084,ko:K08085	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
NGKEMLHH_02981	1280698.AUJS01000029_gene2081	4.42e-52	176.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia,27V5Q@189330|Dorea	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
NGKEMLHH_02982	457412.RSAG_02514	4.47e-198	550.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WI95@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10201	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
NGKEMLHH_02983	1121115.AXVN01000060_gene480	7.75e-194	545.0	COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3XYW6@572511|Blautia	186801|Clostridia	G	COG COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10200	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_02985	1121115.AXVN01000092_gene69	6.4e-210	582.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3XYIT@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_02986	622312.ROSEINA2194_03103	3.23e-213	602.0	COG2304@1|root,COG2304@2|Bacteria,1VDD4@1239|Firmicutes,24B6V@186801|Clostridia	186801|Clostridia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
NGKEMLHH_02987	457412.RSAG_00123	1.35e-155	436.0	2CX3M@1|root,32T12@2|Bacteria,1VTDD@1239|Firmicutes,24Z9E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02988	1121115.AXVN01000020_gene104	1.73e-118	338.0	2C2F1@1|root,33RFH@2|Bacteria,1VSIV@1239|Firmicutes,24ZQ7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02989	457412.RSAG_00121	2.4e-113	327.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3WHDU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
NGKEMLHH_02990	457412.RSAG_00923	0.0	1312.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WG7A@541000|Ruminococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
NGKEMLHH_02991	411462.DORLON_01581	1.37e-248	681.0	2EB9W@1|root,335AE@2|Bacteria,1VENH@1239|Firmicutes,24YVV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02992	411462.DORLON_01580	8.65e-53	166.0	COG2856@1|root,COG2856@2|Bacteria,1V1KH@1239|Firmicutes,24GHH@186801|Clostridia,27WZE@189330|Dorea	186801|Clostridia	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
NGKEMLHH_02993	397290.C810_01812	2.99e-195	550.0	COG0582@1|root,COG0582@2|Bacteria,1V07E@1239|Firmicutes,2480I@186801|Clostridia,27UE7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
NGKEMLHH_02994	411468.CLOSCI_02597	5.21e-29	105.0	2EI8P@1|root,33C01@2|Bacteria,1VN8I@1239|Firmicutes,24X18@186801|Clostridia,2238Y@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02995	411459.RUMOBE_03141	6.62e-268	749.0	COG1653@1|root,COG1653@2|Bacteria,1TSF4@1239|Firmicutes,24DIH@186801|Clostridia,3XZJR@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_02996	411459.RUMOBE_03140	1.48e-56	189.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3XZ6N@572511|Blautia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NGKEMLHH_02997	1121115.AXVN01000002_gene1430	0.0	1316.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia,3XYS4@572511|Blautia	186801|Clostridia	P	COG COG2217 Cation transport ATPase	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
NGKEMLHH_02998	1121115.AXVN01000002_gene1429	2.52e-49	159.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,3Y0EI@572511|Blautia	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_02999	457412.RSAG_00065	6.61e-110	316.0	COG0735@1|root,COG0735@2|Bacteria,1V6DP@1239|Firmicutes,24K9H@186801|Clostridia,3WM1R@541000|Ruminococcaceae	186801|Clostridia	L	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
NGKEMLHH_03000	1410632.JHWW01000021_gene418	3.44e-11	58.5	2DRWB@1|root,33DDT@2|Bacteria,1VKGH@1239|Firmicutes,24VWG@186801|Clostridia,27PQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
NGKEMLHH_03001	457412.RSAG_00063	0.0	1422.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
NGKEMLHH_03002	457412.RSAG_00061	3.97e-43	141.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,3WKEJ@541000|Ruminococcaceae	186801|Clostridia	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NGKEMLHH_03003	457412.RSAG_00060	7.14e-39	129.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,3WKEV@541000|Ruminococcaceae	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NGKEMLHH_03004	1121115.AXVN01000002_gene1424	4.54e-63	192.0	2DMMF@1|root,32SEK@2|Bacteria,1VAB3@1239|Firmicutes,24N8S@186801|Clostridia,3Y0F2@572511|Blautia	186801|Clostridia	S	COG NOG21970 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF2325
NGKEMLHH_03005	1121115.AXVN01000002_gene1423	8.24e-290	791.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia,3XZ1Y@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
NGKEMLHH_03006	457412.RSAG_00057	0.0	945.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,3WGAN@541000|Ruminococcaceae	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydG	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
NGKEMLHH_03007	457412.RSAG_00056	7.31e-244	669.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,3WGPF@541000|Ruminococcaceae	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
NGKEMLHH_03008	397291.C804_06306	1.75e-316	865.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,248JG@186801|Clostridia,27JKE@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HhH-GPD,Transposase_20
NGKEMLHH_03009	1121115.AXVN01000035_gene3855	8.2e-68	205.0	COG1695@1|root,COG1695@2|Bacteria,1VIVQ@1239|Firmicutes,25CR8@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
NGKEMLHH_03010	1121115.AXVN01000035_gene3856	2.06e-104	306.0	COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,24N6S@186801|Clostridia,3Y0AR@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NGKEMLHH_03011	1121115.AXVN01000035_gene3857	1.97e-170	478.0	COG3595@1|root,COG3595@2|Bacteria,1VA9V@1239|Firmicutes,24QYE@186801|Clostridia,3Y0E5@572511|Blautia	186801|Clostridia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
NGKEMLHH_03012	1121115.AXVN01000043_gene3384	8.05e-26	105.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3Y131@572511|Blautia	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NGKEMLHH_03013	1121115.AXVN01000043_gene3383	7.95e-163	459.0	COG0300@1|root,COG0300@2|Bacteria,1UHN7@1239|Firmicutes,25FVQ@186801|Clostridia	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
NGKEMLHH_03014	227882.SAP1_93	1.01e-11	69.7	COG0323@1|root,COG0323@2|Bacteria,2IC33@201174|Actinobacteria	201174|Actinobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
NGKEMLHH_03015	457412.RSAG_01399	0.0	1124.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,3WH72@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_03016	1095750.HMPREF9970_1068	5.27e-246	686.0	COG2801@1|root,COG2801@2|Bacteria,1TT8V@1239|Firmicutes,24BFH@186801|Clostridia,1HW4I@1164882|Lachnoanaerobaculum	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,rve
NGKEMLHH_03018	515620.EUBELI_20171	4.19e-173	488.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,25W4Z@186806|Eubacteriaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K11050	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC_tran,DUF4162
NGKEMLHH_03019	457412.RSAG_00897	3.4e-201	558.0	COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,24BEN@186801|Clostridia,3WM6R@541000|Ruminococcaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992,ko:K11051	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC2_membrane,ABC2_membrane_3
NGKEMLHH_03020	457412.RSAG_03390	0.0	1102.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
NGKEMLHH_03021	742765.HMPREF9457_03045	8.69e-16	75.5	2E5DD@1|root,3305D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03022	1121115.AXVN01000024_gene300	0.0	975.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UVHK@1239|Firmicutes,24DE9@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
NGKEMLHH_03028	1121115.AXVN01000010_gene2784	0.0	968.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,25NJ2@186801|Clostridia,3Y1EP@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3502
NGKEMLHH_03029	457412.RSAG_03402	0.0	1074.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia,3WH01@541000|Ruminococcaceae	186801|Clostridia	G	Carbohydrate kinase, FGGY family protein	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NGKEMLHH_03030	1121115.AXVN01000106_gene671	0.0	1021.0	COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,24A08@186801|Clostridia,3XYUS@572511|Blautia	186801|Clostridia	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
NGKEMLHH_03031	1121115.AXVN01000106_gene670	9.56e-267	729.0	COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,24ARJ@186801|Clostridia,3Y051@572511|Blautia	186801|Clostridia	K	Periplasmic binding protein-like domain	araR	-	-	ko:K02103	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
NGKEMLHH_03032	457412.RSAG_03399	2.7e-200	556.0	COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,24GN2@186801|Clostridia,3WK8B@541000|Ruminococcaceae	186801|Clostridia	S	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
NGKEMLHH_03033	1121115.AXVN01000106_gene668	0.0	2945.0	COG3468@1|root,COG4932@1|root,COG3468@2|Bacteria,COG4932@2|Bacteria,1UVFP@1239|Firmicutes,25MSF@186801|Clostridia,3Y1Y1@572511|Blautia	186801|Clostridia	M	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03034	457412.RSAG_03397	1.33e-89	264.0	2E4RH@1|root,32ZK1@2|Bacteria,1VEUS@1239|Firmicutes,24QIW@186801|Clostridia,3WMFG@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NGKEMLHH_03036	411459.RUMOBE_02301	4.76e-218	602.0	COG1715@1|root,COG1715@2|Bacteria,1V7W8@1239|Firmicutes,25CUM@186801|Clostridia	186801|Clostridia	L	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
NGKEMLHH_03037	658655.HMPREF0988_00013	4.25e-129	370.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,27K28@186928|unclassified Lachnospiraceae	186801|Clostridia	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
NGKEMLHH_03038	1354300.AUQY01000005_gene87	3.33e-63	194.0	COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,24JNV@186801|Clostridia,22IPD@1570339|Peptoniphilaceae	186801|Clostridia	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
NGKEMLHH_03039	1280698.AUJS01000042_gene3271	1.66e-289	790.0	COG1592@1|root,COG1853@1|root,COG1592@2|Bacteria,COG1853@2|Bacteria,1UIDZ@1239|Firmicutes,25EIZ@186801|Clostridia	186801|Clostridia	C	Rubrerythrin	rbr	-	-	-	-	-	-	-	-	-	-	-	Fer4,Flavin_Reduct,Rubrerythrin
NGKEMLHH_03040	457412.RSAG_01545	7.3e-18	82.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3WGPR@541000|Ruminococcaceae	186801|Clostridia	EG	Belongs to the IlvD Edd family	ilvD3	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NGKEMLHH_03041	457412.RSAG_01544	2.19e-219	609.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WI8G@541000|Ruminococcaceae	186801|Clostridia	H	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
NGKEMLHH_03042	478749.BRYFOR_09258	3.94e-117	339.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
NGKEMLHH_03043	1121115.AXVN01000006_gene2186	8.31e-209	577.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3XYQC@572511|Blautia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
NGKEMLHH_03044	457412.RSAG_00839	1.34e-121	347.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia	186801|Clostridia	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
NGKEMLHH_03045	1121115.AXVN01000006_gene2188	1.25e-123	352.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia,3XZU8@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
NGKEMLHH_03047	457421.CBFG_01200	3.09e-58	193.0	COG4974@1|root,COG4974@2|Bacteria,1TQST@1239|Firmicutes,247YT@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
NGKEMLHH_03048	742733.HMPREF9469_05584	2.29e-85	251.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,251Y5@186801|Clostridia,22394@1506553|Lachnoclostridium	186801|Clostridia	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
NGKEMLHH_03049	742733.HMPREF9469_05583	7.6e-118	337.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,251Y5@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
NGKEMLHH_03051	1121115.AXVN01000137_gene1822	0.0	1022.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UVFQ@1239|Firmicutes,25KHE@186801|Clostridia,3Y1SM@572511|Blautia	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03052	1121115.AXVN01000137_gene1823	1.2e-62	198.0	COG1047@1|root,COG1433@1|root,COG1047@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,24BUF@186801|Clostridia,3XYS8@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C,Nitro_FeMo-Co
NGKEMLHH_03053	1121115.AXVN01000032_gene388	4.12e-131	372.0	COG5423@1|root,COG5423@2|Bacteria,1V5IN@1239|Firmicutes,24JW6@186801|Clostridia,3XZUH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NGKEMLHH_03054	457412.RSAG_00175	7.39e-108	311.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,3WIDB@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
NGKEMLHH_03055	457412.RSAG_00176	6.95e-158	445.0	COG0457@1|root,COG0457@2|Bacteria,1UZDE@1239|Firmicutes,24ZJB@186801|Clostridia,3WK93@541000|Ruminococcaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,TPR_19
NGKEMLHH_03056	1121115.AXVN01000030_gene3615	1.06e-237	656.0	28KXK@1|root,2ZADH@2|Bacteria,1V79T@1239|Firmicutes,24K1T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
NGKEMLHH_03057	457412.RSAG_03363	1.64e-174	485.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,3WIIA@541000|Ruminococcaceae	186801|Clostridia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
NGKEMLHH_03058	1121115.AXVN01000030_gene3617	1.25e-119	342.0	COG0454@1|root,COG0454@2|Bacteria,1V9X4@1239|Firmicutes,24G56@186801|Clostridia,3Y07I@572511|Blautia	186801|Clostridia	K	COG COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NGKEMLHH_03059	457412.RSAG_03361	1.18e-50	160.0	2E7R6@1|root,3326H@2|Bacteria,1VGKC@1239|Firmicutes,24QSS@186801|Clostridia,3WQM5@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03060	457412.RSAG_03360	4.1e-251	688.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,3WG84@541000|Ruminococcaceae	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
NGKEMLHH_03061	1121115.AXVN01000030_gene3620	7.73e-185	513.0	COG0500@1|root,COG2226@2|Bacteria,1TT7G@1239|Firmicutes,24E44@186801|Clostridia,3Y0AU@572511|Blautia	186801|Clostridia	Q	NOG31153 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03062	457412.RSAG_03358	6.74e-287	783.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,3WS0T@541000|Ruminococcaceae	186801|Clostridia	H	AMP-binding enzyme	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2,LuxC
NGKEMLHH_03063	457412.RSAG_03357	0.0	913.0	COG1964@1|root,COG1964@2|Bacteria,1TVES@1239|Firmicutes,248NC@186801|Clostridia,3WJ5T@541000|Ruminococcaceae	186801|Clostridia	S	Radical SAM superfamily	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NGKEMLHH_03064	1121115.AXVN01000030_gene3623	9.72e-103	296.0	2E4P6@1|root,32ZHX@2|Bacteria,1VCAE@1239|Firmicutes,24PE5@186801|Clostridia,3Y172@572511|Blautia	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
NGKEMLHH_03065	1121115.AXVN01000030_gene3624	2.06e-125	357.0	COG0500@1|root,COG2226@2|Bacteria,1UDBU@1239|Firmicutes,25I0S@186801|Clostridia,3Y12S@572511|Blautia	186801|Clostridia	H	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
NGKEMLHH_03066	1121115.AXVN01000030_gene3625	1.13e-48	154.0	2EGAW@1|root,33A2R@2|Bacteria,1VMAM@1239|Firmicutes,24WIE@186801|Clostridia,3Y1R7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03067	1121115.AXVN01000030_gene3626	1.72e-269	752.0	COG0247@1|root,COG0493@1|root,COG0247@2|Bacteria,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3Y0YD@572511|Blautia	186801|Clostridia	CE	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_20,Pyr_redox_2
NGKEMLHH_03068	411459.RUMOBE_04204	2.64e-94	275.0	COG1943@1|root,COG1943@2|Bacteria,1V3YY@1239|Firmicutes,24IB0@186801|Clostridia,3Y0EH@572511|Blautia	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
NGKEMLHH_03069	411459.RUMOBE_02313	6.04e-212	587.0	COG4968@1|root,COG4968@2|Bacteria,1VD7G@1239|Firmicutes,25FI2@186801|Clostridia,3Y0V4@572511|Blautia	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
NGKEMLHH_03070	457412.RSAG_04660	5.06e-182	511.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia,3WGVT@541000|Ruminococcaceae	186801|Clostridia	P	Mg2 transporter protein CorA family protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
NGKEMLHH_03071	457412.RSAG_00226	0.0	1296.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WGH8@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	ptsG	-	2.7.1.199	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00809	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
NGKEMLHH_03072	1408324.JNJK01000006_gene1391	4.37e-67	229.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,27J2F@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
NGKEMLHH_03073	1286171.EAL2_c11150	1.64e-27	110.0	COG1652@1|root,COG1652@2|Bacteria,1VBP0@1239|Firmicutes,25DK4@186801|Clostridia	186801|Clostridia	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
NGKEMLHH_03074	199310.c2560	4.96e-248	680.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,3XP3B@561|Escherichia	1236|Gammaproteobacteria	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2076,iSF_1195.SF0545,iSFxv_1172.SFxv_0601,iS_1188.S0553,ic_1306.c2560	Epimerase,GDP_Man_Dehyd
NGKEMLHH_03075	199310.c2561	3.45e-51	171.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
NGKEMLHH_03077	622312.ROSEINA2194_03114	1.62e-75	230.0	28N97@1|root,2ZBD9@2|Bacteria,1UYY7@1239|Firmicutes,24MD6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03079	1392486.JIAF01000003_gene541	5.09e-21	99.8	29XM3@1|root,30JCB@2|Bacteria,4NYH4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03080	345219.Bcoa_0445	5.47e-85	274.0	COG5433@1|root,COG5433@2|Bacteria,1TRZS@1239|Firmicutes,4HUF8@91061|Bacilli,1ZKXP@1386|Bacillus	91061|Bacilli	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4,DDE_Tnp_1_assoc
NGKEMLHH_03081	622312.ROSEINA2194_04061	6.06e-70	221.0	COG0583@1|root,COG0583@2|Bacteria,1V1ND@1239|Firmicutes,25C6Z@186801|Clostridia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NGKEMLHH_03082	622312.ROSEINA2194_04060	1.4e-227	637.0	COG1055@1|root,COG1055@2|Bacteria,1UKAR@1239|Firmicutes,25FT9@186801|Clostridia	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
NGKEMLHH_03083	1235792.C808_03341	3.81e-11	60.8	28M7Q@1|root,2ZAM1@2|Bacteria,1UYX7@1239|Firmicutes,24GTN@186801|Clostridia,27MGQ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative inner membrane protein (DUF1819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1819
NGKEMLHH_03084	1235792.C808_03342	1.12e-32	114.0	COG3655@1|root,COG3655@2|Bacteria,1VEM0@1239|Firmicutes,24QPN@186801|Clostridia,27NRM@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
NGKEMLHH_03085	411461.DORFOR_02079	9.53e-211	588.0	COG3843@1|root,COG3843@2|Bacteria,1UV2C@1239|Firmicutes,248YX@186801|Clostridia	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NGKEMLHH_03086	1121115.AXVN01000052_gene887	0.0	1082.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,3XYKH@572511|Blautia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
NGKEMLHH_03087	1121115.AXVN01000052_gene886	6.64e-170	474.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3XZ5B@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_03088	1121115.AXVN01000052_gene885	0.0	919.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZ8I@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NGKEMLHH_03089	457412.RSAG_01830	0.0	1148.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,3WGIC@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
NGKEMLHH_03090	457412.RSAG_01831	0.0	1351.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia,3WGYT@541000|Ruminococcaceae	186801|Clostridia	S	MCRA family	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
NGKEMLHH_03091	1121115.AXVN01000052_gene882	1.48e-133	378.0	COG1309@1|root,COG1309@2|Bacteria,1UYIP@1239|Firmicutes,249K5@186801|Clostridia,3XZUQ@572511|Blautia	186801|Clostridia	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NGKEMLHH_03092	1121115.AXVN01000052_gene881	7.91e-120	342.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,3XYZI@572511|Blautia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
NGKEMLHH_03093	1121115.AXVN01000052_gene880	2.42e-132	376.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,3XZIN@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
NGKEMLHH_03094	1121115.AXVN01000052_gene879	2.09e-10	55.5	28U02@1|root,2ZG6F@2|Bacteria,1W5KD@1239|Firmicutes,2551S@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03095	1121115.AXVN01000052_gene878	1.39e-131	387.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3XZA6@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
NGKEMLHH_03096	140626.JHWB01000010_gene1877	6.58e-177	549.0	COG1674@1|root,COG1674@2|Bacteria,1TRA4@1239|Firmicutes,249Z1@186801|Clostridia	186801|Clostridia	D	type VII secretion protein EssC	essC	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
NGKEMLHH_03097	1121115.AXVN01000002_gene1394	8.29e-58	187.0	COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,249HH@186801|Clostridia,3XZ06@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	sunS	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
NGKEMLHH_03098	1121115.AXVN01000002_gene1393	0.0	1016.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3XZNF@572511|Blautia	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
NGKEMLHH_03099	1121115.AXVN01000017_gene236	3.72e-120	367.0	COG4967@1|root,COG4967@2|Bacteria,1VKH2@1239|Firmicutes,24UHG@186801|Clostridia	186801|Clostridia	NU	type IV pilus modification protein PilV	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
NGKEMLHH_03101	1121115.AXVN01000066_gene3237	4.15e-231	635.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3XYY9@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NGKEMLHH_03102	457412.RSAG_01028	3.72e-137	393.0	2E1XM@1|root,32X6K@2|Bacteria,1VCEM@1239|Firmicutes,24NS0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03103	457412.RSAG_01027	1.3e-222	616.0	COG1316@1|root,COG1316@2|Bacteria,1UY3P@1239|Firmicutes,24H37@186801|Clostridia,3WJFR@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
NGKEMLHH_03104	457412.RSAG_01026	4.36e-26	101.0	2EB5C@1|root,335VY@2|Bacteria,1VI1F@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03105	1121115.AXVN01000060_gene478	6.33e-189	525.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3XZD4@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10202	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
NGKEMLHH_03106	1235799.C818_03397	1.49e-265	727.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,27IQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NGKEMLHH_03107	1235799.C818_03396	7.9e-136	384.0	COG1396@1|root,COG1396@2|Bacteria,1V9ZU@1239|Firmicutes,24NF3@186801|Clostridia,27Q03@186928|unclassified Lachnospiraceae	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_03108	411469.EUBHAL_01191	5.34e-140	395.0	COG5340@1|root,COG5340@2|Bacteria,1TQSK@1239|Firmicutes,247JC@186801|Clostridia,25VCQ@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
NGKEMLHH_03109	411469.EUBHAL_01192	9.8e-199	551.0	COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,24C3A@186801|Clostridia,25VU5@186806|Eubacteriaceae	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
NGKEMLHH_03110	742735.HMPREF9467_00725	6.83e-228	629.0	COG4974@1|root,COG4974@2|Bacteria,1TQXV@1239|Firmicutes,24884@186801|Clostridia,2206Z@1506553|Lachnoclostridium	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
NGKEMLHH_03111	1121115.AXVN01000055_gene1920	0.0	1644.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3XZEY@572511|Blautia	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
NGKEMLHH_03112	457412.RSAG_03158	0.0	2163.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WG9B@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
NGKEMLHH_03113	457412.RSAG_03160	1.45e-299	816.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NGKEMLHH_03114	1121115.AXVN01000055_gene1916	3.45e-240	659.0	COG5018@1|root,COG5018@2|Bacteria,1TQJZ@1239|Firmicutes,24845@186801|Clostridia,3XYID@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
NGKEMLHH_03115	1121115.AXVN01000055_gene1915	2.52e-263	722.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,3XYVJ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7,Fer4_9
NGKEMLHH_03116	1121115.AXVN01000055_gene1914	1.05e-51	163.0	2CDIT@1|root,338T3@2|Bacteria,1VJ1M@1239|Firmicutes,24SF4@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
NGKEMLHH_03117	1121115.AXVN01000055_gene1913	0.0	1112.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NGKEMLHH_03118	1121115.AXVN01000055_gene1912	1.7e-203	564.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZFZ@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
NGKEMLHH_03119	1121115.AXVN01000055_gene1911	2.25e-239	658.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZP5@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NGKEMLHH_03120	1121115.AXVN01000055_gene1910	2.19e-219	605.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3Y14P@572511|Blautia	186801|Clostridia	E	Oligopeptide/dipeptide transporter, C-terminal region	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NGKEMLHH_03121	1121115.AXVN01000055_gene1909	7.58e-244	669.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3XZ1P@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NGKEMLHH_03122	457412.RSAG_03169	0.0	1038.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,3WJCS@541000|Ruminococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NGKEMLHH_03123	457412.RSAG_03170	0.0	1318.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,3WH32@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
NGKEMLHH_03124	457412.RSAG_01525	0.0	1025.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSFI@1239|Firmicutes,249B8@186801|Clostridia,3WH94@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
NGKEMLHH_03125	457412.RSAG_02116	1.52e-187	528.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NGKEMLHH_03126	1121115.AXVN01000072_gene3913	0.0	987.0	COG1807@1|root,COG1807@2|Bacteria,1V22V@1239|Firmicutes,24GKH@186801|Clostridia,3XYRT@572511|Blautia	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT,PMT_2
NGKEMLHH_03127	457412.RSAG_02118	0.0	1644.0	COG1216@1|root,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
NGKEMLHH_03128	457412.RSAG_02119	0.0	1655.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Methyltransf_23
NGKEMLHH_03129	457412.RSAG_02120	0.0	1456.0	COG2242@1|root,COG2242@2|Bacteria,1TPEE@1239|Firmicutes,24D9B@186801|Clostridia,3WN5Y@541000|Ruminococcaceae	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
NGKEMLHH_03130	1121115.AXVN01000072_gene3917	3.01e-311	847.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3XYUG@572511|Blautia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score 9.49	-	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
NGKEMLHH_03131	1235799.C818_01943	4.46e-110	331.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24B23@186801|Clostridia,27M2S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
NGKEMLHH_03132	1232452.BAIB02000013_gene2258	9.37e-22	93.2	COG0250@1|root,COG0250@2|Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
NGKEMLHH_03133	1121115.AXVN01000106_gene673	0.0	894.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,3XZR1@572511|Blautia	186801|Clostridia	L	COG COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
NGKEMLHH_03135	411489.CLOL250_01621	8.33e-21	85.5	COG1895@1|root,COG1895@2|Bacteria,1V83B@1239|Firmicutes,25IBV@186801|Clostridia,36NUR@31979|Clostridiaceae	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
NGKEMLHH_03136	411468.CLOSCI_01916	2.51e-177	496.0	COG0789@1|root,COG0789@2|Bacteria,1TQYF@1239|Firmicutes,25B18@186801|Clostridia,2245E@1506553|Lachnoclostridium	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
NGKEMLHH_03137	411490.ANACAC_03259	4.32e-149	434.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
NGKEMLHH_03138	1232447.BAHW02000057_gene3383	3.9e-64	211.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,267RH@186813|unclassified Clostridiales	186801|Clostridia	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
NGKEMLHH_03139	457412.RSAG_02327	8.63e-188	523.0	2F1N0@1|root,33UNB@2|Bacteria,1VUUW@1239|Firmicutes,250GG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03141	457412.RSAG_00003	2.31e-69	209.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia,3WKRS@541000|Ruminococcaceae	186801|Clostridia	S	Small, acid-soluble spore protein, alpha beta type	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
NGKEMLHH_03142	457412.RSAG_03028	5.04e-282	769.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,3WHCZ@541000|Ruminococcaceae	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
NGKEMLHH_03143	457412.RSAG_03027	3.22e-135	383.0	2C0IG@1|root,324G4@2|Bacteria,1UQRN@1239|Firmicutes,258HV@186801|Clostridia,3WMTD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03145	457424.BFAG_04840	2.02e-52	175.0	COG2253@1|root,COG2253@2|Bacteria,4P9MT@976|Bacteroidetes,2FU7Q@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03146	457424.BFAG_04841	1.06e-61	195.0	COG3093@1|root,COG3093@2|Bacteria,4NMVH@976|Bacteroidetes,2FUY6@200643|Bacteroidia,4AU5B@815|Bacteroidaceae	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
NGKEMLHH_03147	633697.EubceDRAFT1_1695	1.31e-174	499.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,25VQK@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
NGKEMLHH_03148	1408436.JHXY01000010_gene886	1.38e-77	233.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,25WT8@186806|Eubacteriaceae	186801|Clostridia	C	SUF system FeS assembly protein, NifU family	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
NGKEMLHH_03149	457421.CBFG_01707	1.41e-19	88.6	COG1653@1|root,COG1653@2|Bacteria,1TS2P@1239|Firmicutes,24EIW@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_03150	1232453.BAIF02000038_gene3573	5.63e-228	627.0	COG0849@1|root,COG0849@2|Bacteria,1UJWJ@1239|Firmicutes,25FC9@186801|Clostridia	186801|Clostridia	D	cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03151	742765.HMPREF9457_03058	7.91e-70	210.0	COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,249NG@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36,RepA_N
NGKEMLHH_03152	1121115.AXVN01000042_gene3031	1.83e-148	418.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,3XYPA@572511|Blautia	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
NGKEMLHH_03153	1121115.AXVN01000042_gene3030	4.78e-249	683.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,3XYWD@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
NGKEMLHH_03154	1121115.AXVN01000042_gene3029	1.31e-109	316.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3XZ51@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
NGKEMLHH_03155	1121115.AXVN01000042_gene3028	0.0	1358.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia,3XYTQ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
NGKEMLHH_03156	1121115.AXVN01000042_gene3027	4.05e-64	196.0	2EENY@1|root,338GS@2|Bacteria,1VJM1@1239|Firmicutes,24T09@186801|Clostridia,3Y0JX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03157	457412.RSAG_01717	3.03e-106	306.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia,3WK49@541000|Ruminococcaceae	186801|Clostridia	V	Glycopeptide antibiotics resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NGKEMLHH_03158	1121115.AXVN01000042_gene3025	6.09e-24	90.9	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia,3Y0RQ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03159	1121115.AXVN01000042_gene3024	2.7e-161	451.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,3XYW9@572511|Blautia	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
NGKEMLHH_03160	1121115.AXVN01000042_gene3023	2.17e-213	589.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,3XZ9C@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
NGKEMLHH_03161	1121115.AXVN01000042_gene3022	4.87e-191	530.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,3XZA9@572511|Blautia	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
NGKEMLHH_03162	1121115.AXVN01000042_gene3021	4.46e-226	622.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,3XZ6C@572511|Blautia	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
NGKEMLHH_03163	1121115.AXVN01000042_gene3020	1.94e-315	858.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,3XYP9@572511|Blautia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
NGKEMLHH_03164	1121115.AXVN01000042_gene3019	1.04e-41	136.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,3Y0CS@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
NGKEMLHH_03165	511680.BUTYVIB_00660	9.21e-20	90.1	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,4BYKX@830|Butyrivibrio	186801|Clostridia	L	Bacterial DNA topoisomeraes I ATP-binding domain	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
NGKEMLHH_03166	511680.BUTYVIB_01293	3.14e-31	111.0	2AD7W@1|root,312WU@2|Bacteria,1V7M4@1239|Firmicutes,24M52@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03168	1280698.AUJS01000027_gene2301	1.68e-154	434.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,27W3S@189330|Dorea	186801|Clostridia	V	COG COG1136 ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_03169	1147128.BAST_1689	6.16e-290	806.0	COG1479@1|root,COG1479@2|Bacteria,2I99F@201174|Actinobacteria,4CZ4G@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
NGKEMLHH_03170	457412.RSAG_01024	5.25e-314	859.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia,3WHG7@541000|Ruminococcaceae	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
NGKEMLHH_03171	1121115.AXVN01000044_gene2027	1.11e-82	248.0	COG0250@1|root,COG0250@2|Bacteria,1V3BF@1239|Firmicutes,24G49@186801|Clostridia	186801|Clostridia	K	Transcription termination	-	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
NGKEMLHH_03172	457412.RSAG_01066	7.72e-200	553.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,3WJK2@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NGKEMLHH_03173	457412.RSAG_01067	6.04e-249	683.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,3WI4Q@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
NGKEMLHH_03174	1121115.AXVN01000016_gene3686	1.94e-245	673.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia,3XYZ8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
NGKEMLHH_03175	476272.RUMHYD_01526	6.28e-47	155.0	COG1595@1|root,COG1595@2|Bacteria,1V22M@1239|Firmicutes,24EDG@186801|Clostridia,3Y0NG@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sigma70_r4_2
NGKEMLHH_03176	556261.HMPREF0240_03110	3.85e-15	70.5	2AJW5@1|root,3321D@2|Bacteria,1VFNY@1239|Firmicutes,24RSP@186801|Clostridia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NGKEMLHH_03179	658086.HMPREF0994_04758	4.42e-85	252.0	COG1309@1|root,COG1309@2|Bacteria,1W1AQ@1239|Firmicutes	1239|Firmicutes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03180	1121115.AXVN01000016_gene3691	1.16e-179	501.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3XYTF@572511|Blautia	186801|Clostridia	ET	COG COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	artP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NGKEMLHH_03181	1121115.AXVN01000016_gene3692	3.36e-205	567.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3XZFN@572511|Blautia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
NGKEMLHH_03182	1121115.AXVN01000013_gene3197	9.71e-74	220.0	2F2W4@1|root,33VRY@2|Bacteria,1VW1H@1239|Firmicutes,250T7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03183	411902.CLOBOL_04284	1.6e-108	313.0	2EWMS@1|root,30FQV@2|Bacteria,1UEFU@1239|Firmicutes,25JCN@186801|Clostridia,2223E@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03184	1121115.AXVN01000076_gene2617	1.09e-97	284.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,3Y0J7@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
NGKEMLHH_03185	1121115.AXVN01000076_gene2618	4.35e-120	343.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,3Y0KM@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NGKEMLHH_03186	1121115.AXVN01000076_gene2619	4.24e-290	791.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia,3XZQQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
NGKEMLHH_03187	1121115.AXVN01000076_gene2620	2.94e-194	538.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia,3Y059@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NGKEMLHH_03188	1121115.AXVN01000076_gene2621	5.39e-256	707.0	COG0760@1|root,COG0760@2|Bacteria,1V1WU@1239|Firmicutes,24G3V@186801|Clostridia,3Y03A@572511|Blautia	186801|Clostridia	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
NGKEMLHH_03189	457412.RSAG_03112	0.0	2152.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3WGVW@541000|Ruminococcaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
NGKEMLHH_03190	1121115.AXVN01000076_gene2623	2.66e-138	390.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3XYSI@572511|Blautia	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
NGKEMLHH_03191	457412.RSAG_03114	2.61e-234	644.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia,3WGKW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	cobW
NGKEMLHH_03192	1121115.AXVN01000076_gene2625	1.92e-40	142.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,3XYNY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
NGKEMLHH_03193	1121115.AXVN01000163_gene910	5.98e-55	172.0	COG1396@1|root,COG1396@2|Bacteria,1VARC@1239|Firmicutes,24NFJ@186801|Clostridia,3Y0DI@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_03194	1121115.AXVN01000163_gene909	2.02e-202	563.0	COG3550@1|root,COG3550@2|Bacteria,1TR9A@1239|Firmicutes,24C9K@186801|Clostridia,3Y049@572511|Blautia	186801|Clostridia	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
NGKEMLHH_03195	1121115.AXVN01000163_gene909	2.07e-169	478.0	COG3550@1|root,COG3550@2|Bacteria,1TR9A@1239|Firmicutes,24C9K@186801|Clostridia,3Y049@572511|Blautia	186801|Clostridia	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
NGKEMLHH_03196	585394.RHOM_16925	3.33e-65	199.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
NGKEMLHH_03197	585394.RHOM_16930	3.25e-20	80.9	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
NGKEMLHH_03198	1094508.Tsac_0182	8.78e-132	395.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,42FSS@68295|Thermoanaerobacterales	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_03199	1298598.JCM21714_3863	1.31e-51	169.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,4HC6H@91061|Bacilli	91061|Bacilli	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_03200	1121115.AXVN01000004_gene1926	3.07e-108	319.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3XZDW@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
NGKEMLHH_03201	457412.RSAG_00353	1.62e-277	759.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,3WGQB@541000|Ruminococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NGKEMLHH_03202	457412.RSAG_02434	1.51e-297	812.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NGKEMLHH_03203	483218.BACPEC_01265	3.41e-161	451.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,26A59@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_03204	1121115.AXVN01000130_gene188	2.82e-197	546.0	COG2820@1|root,COG2820@2|Bacteria,1TSEU@1239|Firmicutes,25E2U@186801|Clostridia,3XZ3Q@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
NGKEMLHH_03205	1121115.AXVN01000130_gene189	3.22e-90	264.0	COG5361@1|root,COG5361@2|Bacteria,1U2H3@1239|Firmicutes,24F4F@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
NGKEMLHH_03206	1121115.AXVN01000005_gene2225	1.13e-77	232.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3Y0A9@572511|Blautia	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
NGKEMLHH_03207	1121115.AXVN01000005_gene2224	9.38e-62	209.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,3XZRI@572511|Blautia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
NGKEMLHH_03208	1121115.AXVN01000005_gene2224	5.28e-215	619.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,3XZRI@572511|Blautia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
NGKEMLHH_03209	457412.RSAG_00261	5.76e-84	261.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,3WHZ9@541000|Ruminococcaceae	186801|Clostridia	L	N-6 DNA Methylase	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
NGKEMLHH_03210	457412.RSAG_00261	1.08e-239	665.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,3WHZ9@541000|Ruminococcaceae	186801|Clostridia	L	N-6 DNA Methylase	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
NGKEMLHH_03211	1121115.AXVN01000046_gene2961	4.86e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3Y0HJ@572511|Blautia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
NGKEMLHH_03212	1121115.AXVN01000046_gene2962	3.05e-184	511.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3XZ5M@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
NGKEMLHH_03213	1121115.AXVN01000046_gene2963	4.7e-156	437.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3XZAB@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
NGKEMLHH_03214	457412.RSAG_02864	1.31e-302	827.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,3WG8Z@541000|Ruminococcaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
NGKEMLHH_03215	1121115.AXVN01000046_gene2965	2.1e-94	276.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3XZUB@572511|Blautia	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
NGKEMLHH_03216	1121115.AXVN01000046_gene2966	1.2e-33	115.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,3Y0NM@572511|Blautia	186801|Clostridia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
NGKEMLHH_03217	1121115.AXVN01000046_gene2967	1.46e-112	323.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
NGKEMLHH_03218	1121115.AXVN01000046_gene2968	1.22e-77	231.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3XZZX@572511|Blautia	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
NGKEMLHH_03219	457412.RSAG_02859	4.24e-110	318.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,3WIFT@541000|Ruminococcaceae	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
NGKEMLHH_03220	1121115.AXVN01000046_gene2970	8.56e-90	263.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,3Y02G@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
NGKEMLHH_03221	1121115.AXVN01000046_gene2971	4.1e-39	129.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,3Y0DU@572511|Blautia	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
NGKEMLHH_03222	457412.RSAG_02856	9.39e-123	350.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,3WGYQ@541000|Ruminococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
NGKEMLHH_03223	1121115.AXVN01000046_gene2973	2.29e-64	196.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3Y0BX@572511|Blautia	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
NGKEMLHH_03224	1121115.AXVN01000046_gene2974	1.8e-79	236.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,3XZZG@572511|Blautia	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
NGKEMLHH_03225	457412.RSAG_02853	4.6e-53	166.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,3WJV0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
NGKEMLHH_03226	457412.RSAG_02852	1.57e-33	116.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
NGKEMLHH_03227	1121115.AXVN01000046_gene2977	1.88e-101	293.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3XYIJ@572511|Blautia	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
NGKEMLHH_03228	1121115.AXVN01000046_gene2978	3.41e-151	425.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3XZ7Y@572511|Blautia	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
NGKEMLHH_03229	1121115.AXVN01000046_gene2979	5.64e-84	248.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3XZZ2@572511|Blautia	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
NGKEMLHH_03230	1121115.AXVN01000046_gene2980	1.77e-61	188.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3Y09D@572511|Blautia	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
NGKEMLHH_03231	457412.RSAG_02847	3.05e-199	552.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WGQK@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
NGKEMLHH_03232	742741.HMPREF9475_03774	7.16e-245	676.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,247ME@186801|Clostridia,21XNK@1506553|Lachnoclostridium	186801|Clostridia	L	COG COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NGKEMLHH_03233	1121115.AXVN01000180_gene2885	1.48e-220	607.0	COG2207@1|root,COG2207@2|Bacteria,1VT0T@1239|Firmicutes,24YTA@186801|Clostridia,3Y0YN@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NGKEMLHH_03234	1235802.C823_04452	3.6e-269	775.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,25ZIS@186806|Eubacteriaceae	186801|Clostridia	KL	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
NGKEMLHH_03235	742723.HMPREF9477_01322	7.21e-60	186.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,25CQN@186801|Clostridia,27M9Y@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NGKEMLHH_03236	742740.HMPREF9474_03275	8.06e-232	643.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,220KX@1506553|Lachnoclostridium	186801|Clostridia	H	C-5 cytosine-specific DNA methylase	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,HTH_3
NGKEMLHH_03237	665950.HMPREF1025_01152	1.76e-277	759.0	COG2946@1|root,COG2946@2|Bacteria,1UHNT@1239|Firmicutes,24ZUP@186801|Clostridia,27KKS@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Replication initiation factor	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Rep_trans
NGKEMLHH_03238	411469.EUBHAL_00459	1.52e-64	197.0	296J0@1|root,2ZTUJ@2|Bacteria,1V3IP@1239|Firmicutes,24H9K@186801|Clostridia,25X10@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
NGKEMLHH_03239	1121333.JMLH01000050_gene625	7.68e-309	843.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,3VNWF@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NGKEMLHH_03240	457412.RSAG_01807	3.44e-217	599.0	COG2378@1|root,COG2378@2|Bacteria,1TT23@1239|Firmicutes,248A8@186801|Clostridia,3WGY7@541000|Ruminococcaceae	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
NGKEMLHH_03241	457412.RSAG_01806	4.04e-155	434.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,3WGC2@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
NGKEMLHH_03242	1121115.AXVN01000004_gene1930	8.14e-63	192.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3Y0GK@572511|Blautia	186801|Clostridia	U	COG COG1862 Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
NGKEMLHH_03243	1121115.AXVN01000004_gene1932	2.08e-287	783.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,3XZ2I@572511|Blautia	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
NGKEMLHH_03244	1121115.AXVN01000043_gene3370	2.36e-241	664.0	COG4637@1|root,COG4637@2|Bacteria,1V0EX@1239|Firmicutes,24B14@186801|Clostridia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
NGKEMLHH_03245	1121115.AXVN01000043_gene3369	1.41e-52	166.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,3Y07N@572511|Blautia	186801|Clostridia	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
NGKEMLHH_03246	1121115.AXVN01000097_gene3800	3e-86	253.0	COG3304@1|root,COG3304@2|Bacteria,1VADH@1239|Firmicutes,24NFV@186801|Clostridia,3Y0CX@572511|Blautia	186801|Clostridia	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
NGKEMLHH_03247	1121115.AXVN01000097_gene3801	2.58e-86	253.0	COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,24J94@186801|Clostridia,3Y06G@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
NGKEMLHH_03248	457412.RSAG_01334	3.16e-169	472.0	COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,248AA@186801|Clostridia,3WHIK@541000|Ruminococcaceae	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NGKEMLHH_03249	1121115.AXVN01000009_gene1463	1.36e-170	478.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,3XYI0@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
NGKEMLHH_03250	457412.RSAG_00343	0.0	1145.0	COG0687@1|root,COG1177@1|root,COG0687@2|Bacteria,COG1177@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3WHCV@541000|Ruminococcaceae	186801|Clostridia	P	Spermidine putrescine-binding periplasmic protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
NGKEMLHH_03251	1121115.AXVN01000009_gene1465	1.42e-247	679.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3XZJT@572511|Blautia	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
NGKEMLHH_03252	1121115.AXVN01000009_gene1466	0.0	1053.0	COG1080@1|root,COG1080@2|Bacteria,1VRHN@1239|Firmicutes,24YXY@186801|Clostridia,3XZB5@572511|Blautia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
NGKEMLHH_03253	1121115.AXVN01000009_gene1467	1.41e-263	723.0	COG1146@1|root,COG2006@1|root,COG1146@2|Bacteria,COG2006@2|Bacteria,1TRX2@1239|Firmicutes,249GX@186801|Clostridia,3XZST@572511|Blautia	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_10,Fer4_7
NGKEMLHH_03254	1121115.AXVN01000009_gene1468	2.43e-202	561.0	COG0646@1|root,COG0646@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3XZSY@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
NGKEMLHH_03255	1121115.AXVN01000009_gene1469	1.13e-224	617.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,3XZNJ@572511|Blautia	186801|Clostridia	G	COG COG2017 Galactose mutarotase and related enzymes	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
NGKEMLHH_03256	1121115.AXVN01000009_gene1470	1.11e-302	825.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3XZA1@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NGKEMLHH_03257	97139.C824_02452	1.33e-101	307.0	COG1091@1|root,COG1091@2|Bacteria,1TSX1@1239|Firmicutes,249SC@186801|Clostridia,36R9R@31979|Clostridiaceae	186801|Clostridia	M	dTDP-4-dehydrorhamnose reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RmlD_sub_bind
NGKEMLHH_03258	1123075.AUDP01000009_gene1188	3.04e-16	80.5	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,24QSN@186801|Clostridia,3WJ20@541000|Ruminococcaceae	186801|Clostridia	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
NGKEMLHH_03259	411459.RUMOBE_02360	3.76e-190	530.0	COG0842@1|root,COG0842@2|Bacteria,1TR76@1239|Firmicutes,24A0F@186801|Clostridia,3Y0BD@572511|Blautia	186801|Clostridia	V	COG COG0842 ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
NGKEMLHH_03260	742740.HMPREF9474_01053	4.39e-286	783.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,21YMR@1506553|Lachnoclostridium	186801|Clostridia	L	COG COG3328 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
NGKEMLHH_03262	397291.C804_05728	7.77e-34	118.0	2EA8K@1|root,330PF@2|Bacteria,1VFGQ@1239|Firmicutes,24T8A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03263	622312.ROSEINA2194_01264	1.07e-155	436.0	COG0270@1|root,COG0270@2|Bacteria,1VSZI@1239|Firmicutes,24YBG@186801|Clostridia	186801|Clostridia	L	C-5 cytosine-specific DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	DNA_methylase
NGKEMLHH_03264	622312.ROSEINA2194_01263	1.15e-79	238.0	297FF@1|root,2ZCG2@2|Bacteria,1V2VZ@1239|Firmicutes,24GYA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03265	748224.HMPREF9436_01119	2.29e-109	320.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CbiX
NGKEMLHH_03266	411459.RUMOBE_00394	4.32e-175	488.0	COG5660@1|root,COG5660@2|Bacteria,1VKXY@1239|Firmicutes,24UK9@186801|Clostridia,3Y0RV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
NGKEMLHH_03267	411459.RUMOBE_00395	3.76e-108	312.0	COG1595@1|root,COG1595@2|Bacteria,1UZSS@1239|Firmicutes,24GQJ@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
NGKEMLHH_03268	457412.RSAG_02321	0.0	1042.0	COG1961@1|root,COG1961@2|Bacteria,1TQ8Y@1239|Firmicutes,247WD@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_03269	658086.HMPREF0994_05592	1.24e-32	122.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,27IN1@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_03270	658086.HMPREF0994_05591	5.68e-97	293.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,25C50@186801|Clostridia,27U3E@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_03271	1232447.BAHW02000009_gene426	3.84e-76	246.0	COG3757@1|root,COG5492@1|root,COG3757@2|Bacteria,COG5492@2|Bacteria,1V38V@1239|Firmicutes	1239|Firmicutes	M	Glycosyl hydrolase, family 25	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25,SLH
NGKEMLHH_03272	411490.ANACAC_00003	6.15e-118	341.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
NGKEMLHH_03273	457412.RSAG_01524	4.58e-269	737.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K03406,ko:K10439	ko02010,ko02020,ko02030,map02010,map02020,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	GntR,Peripla_BP_3,Peripla_BP_4
NGKEMLHH_03274	1121115.AXVN01000108_gene620	7.62e-120	343.0	COG3090@1|root,COG3090@2|Bacteria,1V6P9@1239|Firmicutes,24JKS@186801|Clostridia,3XZTR@572511|Blautia	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
NGKEMLHH_03275	457412.RSAG_01560	0.0	2144.0	COG1593@1|root,COG1638@1|root,COG1593@2|Bacteria,COG1638@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3WI33@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctP
NGKEMLHH_03276	1121115.AXVN01000048_gene1297	1.17e-246	676.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,3Y16C@572511|Blautia	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
NGKEMLHH_03277	457412.RSAG_01562	0.0	1156.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WHGV@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NGKEMLHH_03278	1121115.AXVN01000048_gene1295	0.0	1078.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XZEC@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NGKEMLHH_03279	1121115.AXVN01000048_gene1294	1.41e-104	303.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes,24S21@186801|Clostridia,3Y0DP@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NGKEMLHH_03280	457412.RSAG_00929	1.67e-229	634.0	2E3Z2@1|root,32YW0@2|Bacteria,1VGF4@1239|Firmicutes,24PIY@186801|Clostridia,3WM1N@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2953)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
NGKEMLHH_03281	457412.RSAG_00930	1.18e-66	202.0	2CSSR@1|root,33IRN@2|Bacteria,1VG13@1239|Firmicutes,258FD@186801|Clostridia,3WMK4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03282	1121115.AXVN01000002_gene1357	4.65e-40	135.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia,3XZUN@572511|Blautia	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
NGKEMLHH_03283	428126.CLOSPI_01162	1.45e-203	572.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,3VPHK@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NGKEMLHH_03284	471875.RUMLAC_01784	2.81e-148	422.0	COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,25B5A@186801|Clostridia,3WS7I@541000|Ruminococcaceae	186801|Clostridia	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,rve,rve_2
NGKEMLHH_03285	1121333.JMLH01000037_gene2023	2.98e-61	189.0	COG1476@1|root,COG1476@2|Bacteria,1V8YG@1239|Firmicutes,3VS42@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_03286	748224.HMPREF9436_03254	9.49e-12	60.8	2C9RV@1|root,32TYA@2|Bacteria,1VDD3@1239|Firmicutes,24T6T@186801|Clostridia,3WR16@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03290	457412.RSAG_01269	2.42e-162	454.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,248JM@186801|Clostridia,3WHTF@541000|Ruminococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_03291	457412.RSAG_01268	7.97e-199	554.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24B3F@186801|Clostridia,3WRJK@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NGKEMLHH_03292	411463.EUBVEN_01701	3.5e-14	66.6	2EKDM@1|root,33E3X@2|Bacteria,1VP6P@1239|Firmicutes,24WGH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03293	411463.EUBVEN_01697	8.1e-99	306.0	COG3290@1|root,COG3290@2|Bacteria,1UZ9P@1239|Firmicutes,24MR7@186801|Clostridia,25ZE6@186806|Eubacteriaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NGKEMLHH_03294	665950.HMPREF1025_01293	6.04e-282	776.0	COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,24A21@186801|Clostridia,27JSZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
NGKEMLHH_03297	877420.ATVW01000068_gene2409	4.96e-275	756.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,248JG@186801|Clostridia,27JKE@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HhH-GPD,Transposase_20
NGKEMLHH_03298	1232447.BAHW02000010_gene530	9.85e-74	235.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,267JF@186813|unclassified Clostridiales	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
NGKEMLHH_03299	180332.JTGN01000001_gene4614	9.92e-24	102.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia	186801|Clostridia	GM	capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
NGKEMLHH_03300	1280696.ATVY01000148_gene826	1.64e-141	409.0	COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,24CFF@186801|Clostridia,4BYWZ@830|Butyrivibrio	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_03301	457412.RSAG_03062	0.0	1418.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
NGKEMLHH_03302	1121115.AXVN01000005_gene2216	0.0	978.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,3XYWZ@572511|Blautia	186801|Clostridia	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
NGKEMLHH_03303	457412.RSAG_03064	0.0	876.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,3WH9K@541000|Ruminococcaceae	186801|Clostridia	S	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
NGKEMLHH_03304	457412.RSAG_03065	1.42e-270	740.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,3WI13@541000|Ruminococcaceae	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
NGKEMLHH_03305	1121115.AXVN01000005_gene2213	4.54e-302	824.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3XYMS@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NGKEMLHH_03306	1121115.AXVN01000005_gene2212	1.56e-94	275.0	COG4905@1|root,COG4905@2|Bacteria,1VAQJ@1239|Firmicutes,24K5I@186801|Clostridia,3Y0E6@572511|Blautia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NGKEMLHH_03307	457412.RSAG_03068	3.35e-216	597.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
NGKEMLHH_03308	1121115.AXVN01000005_gene2210	1.09e-100	291.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,3XZVS@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
NGKEMLHH_03310	478749.BRYFOR_05763	4.46e-107	321.0	COG2207@1|root,COG2207@2|Bacteria,1UYG6@1239|Firmicutes,24JEP@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NGKEMLHH_03311	397291.C804_01298	6.63e-07	49.7	COG4859@1|root,COG4859@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SUFU
NGKEMLHH_03316	411459.RUMOBE_02137	2.61e-150	441.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247VZ@186801|Clostridia,3XZ4W@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NGKEMLHH_03317	552398.HMPREF0866_03168	9.48e-263	722.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,247ME@186801|Clostridia,3WS4B@541000|Ruminococcaceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NGKEMLHH_03318	457412.RSAG_04683	0.0	1148.0	COG1208@1|root,COG2605@1|root,COG1208@2|Bacteria,COG2605@2|Bacteria,1VU5A@1239|Firmicutes,24BK8@186801|Clostridia,3WJ16@541000|Ruminococcaceae	186801|Clostridia	JM	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
NGKEMLHH_03319	435590.BVU_3009	7.14e-158	445.0	28IAJ@1|root,2Z8D5@2|Bacteria,4NJNA@976|Bacteroidetes,2FQ8K@200643|Bacteroidia,4AMP0@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03320	357276.EL88_08105	5.49e-173	499.0	COG3973@1|root,COG3973@2|Bacteria,4NITV@976|Bacteroidetes,2FPMX@200643|Bacteroidia,4ANB8@815|Bacteroidaceae	976|Bacteroidetes	L	COG COG3973 Superfamily I DNA and RNA helicases	helD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
NGKEMLHH_03321	471875.RUMLAC_00937	5.24e-66	201.0	292IX@1|root,2ZQ2Y@2|Bacteria,1TV0U@1239|Firmicutes,258A6@186801|Clostridia,3WMAJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03322	411463.EUBVEN_01785	1.91e-38	128.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,25XDD@186806|Eubacteriaceae	186801|Clostridia	K	adenine-specific DNA methyltransferase K06223	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NGKEMLHH_03323	457412.RSAG_01589	3.44e-60	186.0	2C1NT@1|root,32JUU@2|Bacteria,1V7IC@1239|Firmicutes,24JFE@186801|Clostridia,3WPC1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03324	457412.RSAG_01590	1.53e-175	491.0	COG4377@1|root,COG4377@2|Bacteria,1V3UF@1239|Firmicutes,24JI9@186801|Clostridia,3WM1X@541000|Ruminococcaceae	186801|Clostridia	S	Putative membrane peptidase family (DUF2324)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2324
NGKEMLHH_03332	658088.HMPREF0987_01101	3.36e-313	855.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,24EUS@186801|Clostridia,27KUD@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_03333	658088.HMPREF0987_01100	0.0	914.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,27J3U@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_03334	658655.HMPREF0988_00519	2.53e-211	585.0	COG1475@1|root,COG1475@2|Bacteria,1UYXH@1239|Firmicutes,24B4U@186801|Clostridia,27M1N@186928|unclassified Lachnospiraceae	186801|Clostridia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03335	658088.HMPREF0987_01098	1.09e-226	624.0	COG1475@1|root,COG1475@2|Bacteria,1V2SD@1239|Firmicutes,24GNZ@186801|Clostridia,27Q08@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03336	658655.HMPREF0988_00517	3.1e-92	269.0	2C62A@1|root,33P1Y@2|Bacteria,1VP22@1239|Firmicutes,24T2I@186801|Clostridia,27RHH@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03337	658655.HMPREF0988_00516	3.05e-189	525.0	COG1961@1|root,COG1961@2|Bacteria,1V247@1239|Firmicutes,24GH4@186801|Clostridia,27MEZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03338	658088.HMPREF0987_01095	0.0	1224.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,2492M@186801|Clostridia,27M1U@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
NGKEMLHH_03339	658088.HMPREF0987_01094	3.82e-82	243.0	COG1396@1|root,COG1396@2|Bacteria,1VGAT@1239|Firmicutes,24QWH@186801|Clostridia,27Q5F@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NGKEMLHH_03340	658088.HMPREF0987_01092	1.88e-39	131.0	29UZW@1|root,30GCX@2|Bacteria,1UFRZ@1239|Firmicutes,25MJP@186801|Clostridia,27SCI@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03341	658088.HMPREF0987_01091	1.3e-69	210.0	COG1396@1|root,COG1396@2|Bacteria,1VID8@1239|Firmicutes,25GM5@186801|Clostridia,27Q6U@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_03342	658088.HMPREF0987_01090	9.87e-70	210.0	COG1476@1|root,COG1476@2|Bacteria,1UMEJ@1239|Firmicutes,25GM4@186801|Clostridia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
NGKEMLHH_03343	658088.HMPREF0987_01089	3.71e-169	471.0	2DZ28@1|root,32V6H@2|Bacteria,1VCMH@1239|Firmicutes,24QBQ@186801|Clostridia,27QVA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03344	511680.BUTYVIB_01332	1.58e-207	580.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,2494S@186801|Clostridia,4BXK3@830|Butyrivibrio	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,SPOB_a
NGKEMLHH_03345	483218.BACPEC_02542	7.81e-106	308.0	2DBPR@1|root,2ZAAE@2|Bacteria,1UHKH@1239|Firmicutes,25E1R@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AgrB
NGKEMLHH_03346	483218.BACPEC_02541	1.26e-28	102.0	2DPR9@1|root,33327@2|Bacteria,1VJE9@1239|Firmicutes,24QUD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03347	1121101.HMPREF1532_00436	2.84e-143	404.0	COG1309@1|root,COG1309@2|Bacteria,4NWKT@976|Bacteroidetes,2FQD3@200643|Bacteroidia,4AQ25@815|Bacteroidaceae	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NGKEMLHH_03348	1121115.AXVN01000008_gene2672	2.28e-116	337.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,24B9N@186801|Clostridia,3XZCY@572511|Blautia	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NGKEMLHH_03349	1121115.AXVN01000008_gene2671	4.28e-176	491.0	COG4608@1|root,COG4608@2|Bacteria,1UV6D@1239|Firmicutes,25BCP@186801|Clostridia	186801|Clostridia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NGKEMLHH_03351	1232447.BAHW02000055_gene3250	6.58e-147	424.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,268MH@186813|unclassified Clostridiales	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_03352	1121115.AXVN01000037_gene3254	1.73e-89	262.0	COG0355@1|root,COG0355@2|Bacteria,1TTR7@1239|Firmicutes,25MVC@186801|Clostridia,3Y1KM@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_DE,ATP-synt_DE_N
NGKEMLHH_03353	1121115.AXVN01000037_gene3255	0.0	909.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3Y1D7@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
NGKEMLHH_03354	411459.RUMOBE_03063	9.64e-42	137.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,3Y0RP@572511|Blautia	186801|Clostridia	P	COG COG1918 Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NGKEMLHH_03355	411459.RUMOBE_03064	4.01e-44	143.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,3Y0MM@572511|Blautia	186801|Clostridia	P	COG COG1918 Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NGKEMLHH_03356	1121115.AXVN01000202_gene840	1.23e-192	537.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,24DGQ@186801|Clostridia,3Y2AQ@572511|Blautia	186801|Clostridia	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
NGKEMLHH_03357	1235793.C809_01488	1.09e-24	102.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,27JDG@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_03359	1121115.AXVN01000084_gene1830	5.31e-242	666.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,3XZSW@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
NGKEMLHH_03360	1121115.AXVN01000034_gene3860	5.41e-47	150.0	2CD8N@1|root,3400U@2|Bacteria,1VWX5@1239|Firmicutes,252JF@186801|Clostridia,3Y1RB@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03361	457412.RSAG_02504	7.32e-282	788.0	COG2909@1|root,COG2909@2|Bacteria,1TT0M@1239|Firmicutes,24BMZ@186801|Clostridia,3WHDT@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE
NGKEMLHH_03362	457412.RSAG_02504	1.55e-297	829.0	COG2909@1|root,COG2909@2|Bacteria,1TT0M@1239|Firmicutes,24BMZ@186801|Clostridia,3WHDT@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE
NGKEMLHH_03363	457412.RSAG_02505	3.78e-57	177.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	sacC5	-	2.7.1.4,3.2.1.80	ko:K00847,ko:K03332	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R00879,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N,PfkB
NGKEMLHH_03364	457412.RSAG_02506	0.0	1024.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3WHUY@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
NGKEMLHH_03365	1121115.AXVN01000060_gene470	0.0	1144.0	COG1653@1|root,COG1653@2|Bacteria,1TS6D@1239|Firmicutes,248CI@186801|Clostridia,3XZ5C@572511|Blautia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
NGKEMLHH_03366	1121115.AXVN01000060_gene471	3.2e-209	578.0	COG0395@1|root,COG0395@2|Bacteria,1TQ9F@1239|Firmicutes,24846@186801|Clostridia,3XZ22@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NGKEMLHH_03367	457412.RSAG_02509	4.41e-219	605.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,248XU@186801|Clostridia,3WHDQ@541000|Ruminococcaceae	186801|Clostridia	P	carbohydrate ABC transporter membrane protein 1 CUT1 family	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NGKEMLHH_03368	1121115.AXVN01000060_gene474	4.33e-236	650.0	COG1609@1|root,COG1609@2|Bacteria,1TSU0@1239|Firmicutes,24C3S@186801|Clostridia,3XZBF@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NGKEMLHH_03369	1121115.AXVN01000006_gene2129	0.0	1001.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3XYMY@572511|Blautia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
NGKEMLHH_03370	500632.CLONEX_00007	4.85e-280	764.0	COG2946@1|root,COG2946@2|Bacteria,1UE6H@1239|Firmicutes,24AH3@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Rep_trans
NGKEMLHH_03371	457412.RSAG_00689	1.56e-113	325.0	COG4728@1|root,COG4728@2|Bacteria,1VENJ@1239|Firmicutes,24SFD@186801|Clostridia,3WMPN@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
NGKEMLHH_03372	457412.RSAG_00688	4.02e-121	345.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24HQM@186801|Clostridia,3WJG3@541000|Ruminococcaceae	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
NGKEMLHH_03373	1042156.CXIVA_08070	4.34e-200	554.0	COG4974@1|root,COG4974@2|Bacteria,1V1BF@1239|Firmicutes,25C3Y@186801|Clostridia,36WP7@31979|Clostridiaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
NGKEMLHH_03374	742733.HMPREF9469_03114	3.23e-123	357.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia,2247R@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_03375	411459.RUMOBE_00525	3.78e-127	366.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia,3XYHB@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	ytrB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_03376	1235790.C805_01110	3.15e-129	372.0	COG3279@1|root,COG3279@2|Bacteria,1V0QJ@1239|Firmicutes,24E66@186801|Clostridia,25WQA@186806|Eubacteriaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NGKEMLHH_03377	622312.ROSEINA2194_00593	6.96e-52	166.0	COG1476@1|root,COG1476@2|Bacteria,1VHT2@1239|Firmicutes,24QWU@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_03378	1121115.AXVN01000038_gene3328	0.0	1046.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NGKEMLHH_03379	1232447.BAHW02000048_gene2958	6.99e-91	291.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,26ADQ@186813|unclassified Clostridiales	186801|Clostridia	T	Psort location Cytoplasmic, score 9.97	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NGKEMLHH_03388	1235799.C818_02633	1.48e-119	365.0	COG3831@1|root,COG3831@2|Bacteria	2|Bacteria	-	-	-	-	2.4.2.30	ko:K10798	ko03410,ko04210,ko04212,ko04214,ko04217,map03410,map04210,map04212,map04214,map04217	M00296	-	-	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400	-	-	-	DUF4240,PARP,WGR
NGKEMLHH_03400	1232447.BAHW02000055_gene3182	5.19e-59	194.0	COG4965@1|root,COG4965@2|Bacteria,1V6PB@1239|Firmicutes,24JBR@186801|Clostridia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
NGKEMLHH_03402	411902.CLOBOL_04309	6.5e-161	462.0	COG0732@1|root,COG0732@2|Bacteria	2|Bacteria	V	type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
NGKEMLHH_03403	411902.CLOBOL_04310	5.28e-122	348.0	COG0732@1|root,COG0732@2|Bacteria	2|Bacteria	V	type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
NGKEMLHH_03404	658086.HMPREF0994_01172	4.92e-68	213.0	COG4942@1|root,COG4942@2|Bacteria,1V67C@1239|Firmicutes,25FCI@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NGKEMLHH_03405	658086.HMPREF0994_01173	1.06e-90	266.0	2DQ57@1|root,334TC@2|Bacteria,1VIYA@1239|Firmicutes,24TSF@186801|Clostridia,27S5T@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03406	411490.ANACAC_02558	6.06e-91	283.0	COG1388@1|root,COG1388@2|Bacteria,1V4FJ@1239|Firmicutes,24IPI@186801|Clostridia	186801|Clostridia	M	LysM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM
NGKEMLHH_03407	742733.HMPREF9469_06026	6.23e-68	221.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,221TB@1506553|Lachnoclostridium	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
NGKEMLHH_03408	742733.HMPREF9469_06026	5.78e-81	256.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,221TB@1506553|Lachnoclostridium	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
NGKEMLHH_03409	871968.DESME_14275	1.45e-30	119.0	COG1082@1|root,COG1082@2|Bacteria,1TSJP@1239|Firmicutes,24CUQ@186801|Clostridia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NGKEMLHH_03410	585501.HMPREF6123_1881	4.46e-131	379.0	COG1216@1|root,COG1216@2|Bacteria,1TP56@1239|Firmicutes,24AEY@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
NGKEMLHH_03411	457412.RSAG_00569	0.0	901.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,3WH5V@541000|Ruminococcaceae	186801|Clostridia	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NGKEMLHH_03412	411459.RUMOBE_00583	4.76e-73	219.0	296J0@1|root,2ZR9N@2|Bacteria,1VAUS@1239|Firmicutes,24PMT@186801|Clostridia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
NGKEMLHH_03413	1121115.AXVN01000024_gene303	5.88e-163	456.0	COG5036@1|root,COG5036@2|Bacteria,1V27Y@1239|Firmicutes,25D4R@186801|Clostridia,3Y0DX@572511|Blautia	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
NGKEMLHH_03414	1121115.AXVN01000024_gene302	1.89e-188	523.0	2CABP@1|root,2Z7KZ@2|Bacteria,1U7V1@1239|Firmicutes,24C2H@186801|Clostridia,3Y1UZ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03415	411459.RUMOBE_01403	1.58e-299	818.0	COG0265@1|root,COG0265@2|Bacteria,1TTAZ@1239|Firmicutes,24BWH@186801|Clostridia,3XZG2@572511|Blautia	186801|Clostridia	O	COG COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NGKEMLHH_03416	457412.RSAG_01004	4.38e-191	531.0	COG2207@1|root,COG2207@2|Bacteria,1V1VJ@1239|Firmicutes,24G3A@186801|Clostridia,3WRI1@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NGKEMLHH_03417	1121115.AXVN01000015_gene3728	2.32e-172	481.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,3XYKS@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
NGKEMLHH_03418	1121115.AXVN01000015_gene3729	2.81e-64	196.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,3Y07E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
NGKEMLHH_03419	457412.RSAG_02418	0.0	2182.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3WGCC@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NGKEMLHH_03420	1121115.AXVN01000015_gene3731	7.87e-243	666.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,247RJ@186801|Clostridia,3XZQB@572511|Blautia	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
NGKEMLHH_03421	457412.RSAG_02421	0.0	1509.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,3WGBC@541000|Ruminococcaceae	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
NGKEMLHH_03422	457412.RSAG_02422	7.96e-221	608.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,3WSMJ@541000|Ruminococcaceae	186801|Clostridia	K	PFAM AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NGKEMLHH_03423	457412.RSAG_02423	1.09e-315	858.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,248X0@186801|Clostridia,3WIWK@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_03424	457412.RSAG_02424	1.65e-211	584.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,3WHPR@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_03425	1121115.AXVN01000015_gene3736	4.82e-188	523.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,3Y0FC@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_03426	457412.RSAG_02426	1.1e-153	432.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,3WKI6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
NGKEMLHH_03427	457412.RSAG_02427	0.0	1499.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,3WGBC@541000|Ruminococcaceae	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
NGKEMLHH_03428	1121115.AXVN01000015_gene3739	0.0	1215.0	COG2972@1|root,COG2972@2|Bacteria,1VS09@1239|Firmicutes,24AV3@186801|Clostridia,3Y1HV@572511|Blautia	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NGKEMLHH_03429	1121115.AXVN01000015_gene3740	2.1e-165	464.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UUUY@1239|Firmicutes,25KCT@186801|Clostridia,3Y1GV@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NGKEMLHH_03430	1121115.AXVN01000015_gene3741	3.42e-297	811.0	COG1653@1|root,COG1653@2|Bacteria,1TRAX@1239|Firmicutes,2497E@186801|Clostridia,3Y0JS@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
NGKEMLHH_03431	1121115.AXVN01000015_gene3742	1.25e-207	575.0	COG1175@1|root,COG1175@2|Bacteria,1UZE5@1239|Firmicutes,25MIN@186801|Clostridia,3Y15U@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_03432	1121115.AXVN01000015_gene3743	6.12e-194	538.0	COG0395@1|root,COG0395@2|Bacteria,1TSM1@1239|Firmicutes,25C4V@186801|Clostridia,3Y1GS@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_03433	457412.RSAG_00709	0.0	917.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NGKEMLHH_03434	1121115.AXVN01000061_gene495	4.2e-215	595.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia,3Y17Y@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_03435	1121115.AXVN01000061_gene496	2.71e-177	496.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,3Y023@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NGKEMLHH_03436	1121115.AXVN01000061_gene497	0.0	1645.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3Y07X@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NGKEMLHH_03437	1121115.AXVN01000061_gene498	3.07e-309	840.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,3XYMM@572511|Blautia	186801|Clostridia	S	N-methylation of lysine residues in flagellin	fliU	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
NGKEMLHH_03438	457412.RSAG_00704	1.42e-205	572.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,3WIGP@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NGKEMLHH_03439	1226325.HMPREF1548_06090	3.97e-244	685.0	COG1653@1|root,COG1653@2|Bacteria,1VC36@1239|Firmicutes,24JE6@186801|Clostridia	186801|Clostridia	G	transport	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NGKEMLHH_03440	1121115.AXVN01000030_gene3627	1.31e-222	637.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3Y192@572511|Blautia	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	mop	-	1.2.99.7	ko:K07469	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
NGKEMLHH_03442	411902.CLOBOL_05556	1.67e-76	235.0	COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,24B05@186801|Clostridia,220QB@1506553|Lachnoclostridium	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
NGKEMLHH_03444	1256908.HMPREF0373_00580	9.22e-05	45.8	COG1595@1|root,COG1595@2|Bacteria,1V8GV@1239|Firmicutes,24JEH@186801|Clostridia,25WXI@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
NGKEMLHH_03445	457412.RSAG_00597	8.47e-207	572.0	COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,248CX@186801|Clostridia,3WGE2@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NGKEMLHH_03446	457412.RSAG_01809	9.66e-177	493.0	COG3843@1|root,COG3843@2|Bacteria,1TR9B@1239|Firmicutes,24A36@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NGKEMLHH_03447	1227349.C170_26948	1.54e-39	153.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,4HB0G@91061|Bacilli,26UZ8@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_03448	658086.HMPREF0994_02204	2.25e-126	358.0	2EWHY@1|root,33PW8@2|Bacteria,1VTIC@1239|Firmicutes,24Y33@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03449	457412.RSAG_00893	6.87e-24	92.0	2C9RV@1|root,32WXH@2|Bacteria,1VCZ0@1239|Firmicutes,25AYI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03450	457412.RSAG_00892	4.72e-107	308.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,3WIK4@541000|Ruminococcaceae	186801|Clostridia	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
NGKEMLHH_03451	457412.RSAG_00891	1.69e-182	507.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,3WHH1@541000|Ruminococcaceae	186801|Clostridia	S	Peroxide stress protein YaaA	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
NGKEMLHH_03452	457412.RSAG_01049	2.18e-213	593.0	COG1653@1|root,COG1653@2|Bacteria,1TQJE@1239|Firmicutes,2496C@186801|Clostridia,3WK4C@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_03453	1121115.AXVN01000191_gene1033	9.11e-198	548.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia,3XZPS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
NGKEMLHH_03454	457412.RSAG_00013	1.67e-249	684.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,3WH5D@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NGKEMLHH_03455	457412.RSAG_00012	1.83e-150	423.0	2E2IE@1|root,32XN3@2|Bacteria,1VD21@1239|Firmicutes,24KKS@186801|Clostridia,3WM0H@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03456	457412.RSAG_00011	0.0	1295.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,3WGM7@541000|Ruminococcaceae	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
NGKEMLHH_03457	457412.RSAG_00010	4.3e-189	525.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,3WNY9@541000|Ruminococcaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	yjbM	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NGKEMLHH_03458	1121115.AXVN01000002_gene1372	0.0	954.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia,3XZA8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NGKEMLHH_03459	457412.RSAG_00008	6.8e-221	609.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia,3WIGE@541000|Ruminococcaceae	186801|Clostridia	S	sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
NGKEMLHH_03460	1121115.AXVN01000002_gene1370	2.51e-94	281.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,3XZBA@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03461	1121115.AXVN01000002_gene1369	1.66e-111	320.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,3XZXZ@572511|Blautia	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
NGKEMLHH_03462	1121115.AXVN01000002_gene1368	4.62e-125	356.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3XZUU@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
NGKEMLHH_03463	1121115.AXVN01000002_gene1367	1.27e-90	265.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3Y038@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
NGKEMLHH_03464	411459.RUMOBE_02104	9.38e-137	388.0	COG1595@1|root,COG1595@2|Bacteria,1TQ1Q@1239|Firmicutes,25JVV@186801|Clostridia,3Y1NW@572511|Blautia	186801|Clostridia	K	Putative helix-turn-helix protein, YlxM / p13 like	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03465	411459.RUMOBE_02102	1.37e-19	79.0	2924K@1|root,2ZPPK@2|Bacteria,1W5V4@1239|Firmicutes,256EY@186801|Clostridia	186801|Clostridia	S	Psort location Extracellular, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03466	457412.RSAG_02705	2.87e-133	381.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia,3WI9G@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
NGKEMLHH_03467	457412.RSAG_02706	6.5e-73	219.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia,3WK33@541000|Ruminococcaceae	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
NGKEMLHH_03468	457412.RSAG_02707	1.29e-106	307.0	2BZUE@1|root,31TAF@2|Bacteria,1URY6@1239|Firmicutes,24XVK@186801|Clostridia,3WQSR@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03470	435590.BVU_0009	3.55e-294	809.0	COG1022@1|root,COG1022@2|Bacteria,4NGFQ@976|Bacteroidetes,2FN1X@200643|Bacteroidia,4AKRT@815|Bacteroidaceae	976|Bacteroidetes	I	Psort location CytoplasmicMembrane, score 9.82	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
NGKEMLHH_03471	357276.EL88_15875	4.27e-14	67.0	2EUHM@1|root,2ZRQX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03472	1121115.AXVN01000021_gene1685	1.87e-144	416.0	COG0596@1|root,COG0596@2|Bacteria,1TR3M@1239|Firmicutes,24DR9@186801|Clostridia,3XYQ9@572511|Blautia	186801|Clostridia	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
NGKEMLHH_03473	1121115.AXVN01000032_gene402	9.36e-317	882.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3XZ6B@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
NGKEMLHH_03474	1121115.AXVN01000014_gene1244	4.72e-212	587.0	COG2367@1|root,COG2367@2|Bacteria,1VSGY@1239|Firmicutes,24XQF@186801|Clostridia,3XZU7@572511|Blautia	186801|Clostridia	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
NGKEMLHH_03475	1121115.AXVN01000037_gene3238	1.25e-148	418.0	COG0629@1|root,COG0629@2|Bacteria,1TRWZ@1239|Firmicutes,248UD@186801|Clostridia,3XZI3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ssb1	-	-	-	-	-	-	-	-	-	-	-	SSB
NGKEMLHH_03476	457412.RSAG_00953	9.15e-109	316.0	COG4916@1|root,COG4916@2|Bacteria	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
NGKEMLHH_03477	457412.RSAG_04701	2.67e-101	293.0	2EB8P@1|root,33598@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03479	457412.RSAG_02464	5.15e-90	265.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia,3WK5R@541000|Ruminococcaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03480	1121115.AXVN01000051_gene796	0.0	1283.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3XZ2F@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
NGKEMLHH_03481	1121115.AXVN01000051_gene795	1.35e-203	564.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,3XYXT@572511|Blautia	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
NGKEMLHH_03482	457412.RSAG_02468	3.06e-198	548.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia,3WSIZ@541000|Ruminococcaceae	186801|Clostridia	S	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
NGKEMLHH_03483	1121115.AXVN01000051_gene793	1.05e-187	530.0	2EWK9@1|root,33PYD@2|Bacteria,1VTXK@1239|Firmicutes,24ZC9@186801|Clostridia,3Y0MZ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03484	1121115.AXVN01000051_gene792	0.0	1332.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia,3XZ0C@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	helD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
NGKEMLHH_03485	1121115.AXVN01000163_gene907	3.05e-132	376.0	COG1102@1|root,COG1102@2|Bacteria,1V4ZA@1239|Firmicutes,24JCT@186801|Clostridia	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NGKEMLHH_03486	411470.RUMGNA_00702	7.73e-258	706.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,249TP@186801|Clostridia,3Y2B0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
NGKEMLHH_03487	411470.RUMGNA_00703	3.57e-113	333.0	COG0582@1|root,COG0582@2|Bacteria,1TSR6@1239|Firmicutes,249IV@186801|Clostridia,3Y187@572511|Blautia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
NGKEMLHH_03488	521095.Apar_1222	6.88e-19	78.6	2DT34@1|root,33IH4@2|Bacteria	2|Bacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NGKEMLHH_03489	435590.BVU_3015	2.76e-59	192.0	COG1979@1|root,COG1979@2|Bacteria,4NF1D@976|Bacteroidetes,2FPAW@200643|Bacteroidia,4AK9J@815|Bacteroidaceae	976|Bacteroidetes	C	Psort location Cytoplasmic, score	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
NGKEMLHH_03491	1256908.HMPREF0373_00498	0.0	945.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,249JM@186801|Clostridia,25VXX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
NGKEMLHH_03492	1235802.C823_04451	2.88e-158	478.0	COG0514@1|root,COG0514@2|Bacteria,1UN25@1239|Firmicutes,24ENK@186801|Clostridia,25Y53@186806|Eubacteriaceae	186801|Clostridia	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
NGKEMLHH_03495	457412.RSAG_00225	8.38e-186	517.0	COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,249XA@186801|Clostridia,3WIRH@541000|Ruminococcaceae	186801|Clostridia	K	CAT RNA binding domain	bglG	-	-	ko:K03480	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
NGKEMLHH_03496	1121115.AXVN01000064_gene4022	1.8e-82	267.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	1239|Firmicutes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
NGKEMLHH_03497	1121115.AXVN01000010_gene2776	1.86e-187	523.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,3XYMF@572511|Blautia	186801|Clostridia	P	COG COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
NGKEMLHH_03498	1203611.KB894559_gene22	1.96e-41	139.0	COG3616@1|root,COG3616@2|Bacteria,4P8JC@976|Bacteroidetes,2FRYU@200643|Bacteroidia	976|Bacteroidetes	E	Protein of unknown function (DUF2958)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2958
NGKEMLHH_03499	457424.BFAG_01400	1.42e-81	251.0	COG0286@1|root,COG0286@2|Bacteria,4P0EH@976|Bacteroidetes,2G3BK@200643|Bacteroidia,4AWD5@815|Bacteroidaceae	976|Bacteroidetes	V	N-6 DNA Methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_Mtase
NGKEMLHH_03500	1121115.AXVN01000006_gene2123	2.12e-253	694.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,3XYX3@572511|Blautia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
NGKEMLHH_03501	457412.RSAG_00741	2.86e-304	831.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3WGTJ@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
NGKEMLHH_03502	1121115.AXVN01000006_gene2121	1.09e-104	303.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3Y0AW@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NGKEMLHH_03503	1121115.AXVN01000006_gene2120	5.28e-282	771.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XZ67@572511|Blautia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NGKEMLHH_03504	1121115.AXVN01000006_gene2119	6.48e-104	300.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3XZVP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
NGKEMLHH_03505	457412.RSAG_00737	0.0	1590.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3WHCP@541000|Ruminococcaceae	186801|Clostridia	P	E1-E2 ATPase	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
NGKEMLHH_03506	457412.RSAG_04756	0.0	1296.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WH4U@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain	ams	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
NGKEMLHH_03507	1121115.AXVN01000134_gene415	1.54e-311	847.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,3XZ64@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
NGKEMLHH_03508	199310.c3582	2.76e-108	313.0	COG1846@1|root,COG1846@2|Bacteria,1NWZ4@1224|Proteobacteria,1RPCJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional	mprA	-	-	ko:K15974	-	M00701	-	-	ko00000,ko00002,ko03000	-	-	-	MarR
NGKEMLHH_03509	556261.HMPREF0240_04555	4.72e-55	176.0	2DNNA@1|root,32Y8E@2|Bacteria,1UKCJ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03510	556261.HMPREF0240_04556	4.53e-176	497.0	COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes,24B89@186801|Clostridia,36GS0@31979|Clostridiaceae	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_2
NGKEMLHH_03511	1121115.AXVN01000045_gene2052	3.17e-128	367.0	COG0543@1|root,COG0543@2|Bacteria,1TQBZ@1239|Firmicutes,248GQ@186801|Clostridia,3XYPT@572511|Blautia	186801|Clostridia	C	Oxidoreductase NAD-binding domain	asrB	-	-	ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
NGKEMLHH_03512	1121115.AXVN01000045_gene2053	4.85e-232	638.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,3XZCG@572511|Blautia	186801|Clostridia	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	asrC	-	-	ko:K00385	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4,Fer4_10,Fer4_21,Fer4_4,Fer4_6,NIR_SIR,NIR_SIR_ferr
NGKEMLHH_03513	457412.RSAG_01450	0.0	1113.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3WGUV@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
NGKEMLHH_03515	645991.Sgly_1457	5.76e-44	149.0	COG3335@1|root,COG3335@2|Bacteria,1UZI4@1239|Firmicutes,24BY8@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
NGKEMLHH_03517	1121115.AXVN01000051_gene812	5.93e-164	459.0	COG3279@1|root,COG3279@2|Bacteria,1UYV2@1239|Firmicutes,24F5U@186801|Clostridia,3Y1SH@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NGKEMLHH_03518	1121115.AXVN01000051_gene811	5.28e-122	348.0	2EHNM@1|root,33BEE@2|Bacteria,1VNIH@1239|Firmicutes,24PUV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03519	457412.RSAG_04751	1.03e-182	511.0	COG5279@1|root,COG5279@2|Bacteria,1UT8R@1239|Firmicutes,24CQF@186801|Clostridia,3WRJU@541000|Ruminococcaceae	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NGKEMLHH_03521	1121115.AXVN01000003_gene1638	4.76e-159	445.0	COG2315@1|root,COG3695@1|root,COG2315@2|Bacteria,COG3695@2|Bacteria,1VVT6@1239|Firmicutes,25EAU@186801|Clostridia,3Y0FV@572511|Blautia	186801|Clostridia	L	YjbR	ogt	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,YjbR
NGKEMLHH_03522	585394.RHOM_16375	3.4e-164	459.0	COG3279@1|root,COG3279@2|Bacteria,1V0X7@1239|Firmicutes,24EP3@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
NGKEMLHH_03523	511680.BUTYVIB_01338	2.07e-68	207.0	COG1396@1|root,COG1396@2|Bacteria,1V9SP@1239|Firmicutes,24MFU@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
NGKEMLHH_03525	1121115.AXVN01000047_gene1255	0.0	1315.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,3XZC9@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
NGKEMLHH_03526	457412.RSAG_01868	0.0	2947.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,3WGJN@541000|Ruminococcaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
NGKEMLHH_03527	1121115.AXVN01000047_gene1253	6.51e-247	678.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3XYGT@572511|Blautia	186801|Clostridia	H	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
NGKEMLHH_03528	457412.RSAG_01870	5.69e-180	507.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the TelA family	-	-	-	-	-	-	-	-	-	-	-	-	TelA
NGKEMLHH_03529	435590.BVU_3195	1.43e-52	178.0	COG4584@1|root,COG4584@2|Bacteria,4P0IM@976|Bacteroidetes,2FPW1@200643|Bacteroidia,4APJZ@815|Bacteroidaceae	976|Bacteroidetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
NGKEMLHH_03530	435590.BVU_3194	9.53e-65	203.0	COG1484@1|root,COG1484@2|Bacteria,4NM7S@976|Bacteroidetes,2FQJH@200643|Bacteroidia,4AWBX@815|Bacteroidaceae	976|Bacteroidetes	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
NGKEMLHH_03531	272559.BF9343_3964	5.3e-76	232.0	COG1484@1|root,COG1484@2|Bacteria,4NM7S@976|Bacteroidetes,2FQJH@200643|Bacteroidia,4AWBX@815|Bacteroidaceae	976|Bacteroidetes	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
NGKEMLHH_03532	1121115.AXVN01000002_gene1340	2.38e-48	167.0	COG0534@1|root,COG0534@2|Bacteria,1V10K@1239|Firmicutes,24CIC@186801|Clostridia	186801|Clostridia	TV	MatE	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MatE
NGKEMLHH_03533	658088.HMPREF0987_01114	6.86e-79	237.0	28H7M@1|root,2Z7JU@2|Bacteria,1UG4F@1239|Firmicutes,24B1Y@186801|Clostridia,27JWC@186928|unclassified Lachnospiraceae	186801|Clostridia	S	phage major tail protein, phi13 family	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03534	658088.HMPREF0987_01113	1.12e-83	247.0	2990R@1|root,2ZW4F@2|Bacteria,1V3SD@1239|Firmicutes,24HA5@186801|Clostridia,27N4K@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03535	658088.HMPREF0987_01112	2.21e-31	109.0	2BX2H@1|root,32Y2N@2|Bacteria,1VEEG@1239|Firmicutes,24RM5@186801|Clostridia,27PT3@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03536	457412.RSAG_03137	1.02e-229	632.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,3WITB@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	lytC_3	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NGKEMLHH_03537	1410632.JHWW01000010_gene2630	4.64e-279	780.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,27J0U@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Pyruvate formate lyase-like	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NGKEMLHH_03538	435590.BVU_3072	3.31e-222	613.0	COG3710@1|root,COG3710@2|Bacteria,4PJP7@976|Bacteroidetes,2FSIW@200643|Bacteroidia,4AR1T@815|Bacteroidaceae	976|Bacteroidetes	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
NGKEMLHH_03539	1121115.AXVN01000047_gene1256	5.89e-105	315.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3XYNA@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purF_1	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
NGKEMLHH_03540	1121115.AXVN01000047_gene1257	4.91e-94	279.0	COG1033@1|root,COG1033@2|Bacteria,1VTBG@1239|Firmicutes,24YPV@186801|Clostridia,3Y1R8@572511|Blautia	186801|Clostridia	S	growth of symbiont in host cell	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03541	1121115.AXVN01000047_gene1258	1.52e-43	141.0	COG1396@1|root,COG1396@2|Bacteria,1UHV9@1239|Firmicutes,25E41@186801|Clostridia,3Y0RB@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NGKEMLHH_03542	592026.GCWU0000282_002318	2.35e-142	402.0	COG3335@1|root,COG3335@2|Bacteria,1UZI4@1239|Firmicutes,24BY8@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
NGKEMLHH_03543	592026.GCWU0000282_001935	1.04e-106	309.0	COG3415@1|root,COG3415@2|Bacteria,1V3AV@1239|Firmicutes,24G92@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32
NGKEMLHH_03544	411459.RUMOBE_01862	1.45e-158	444.0	COG0745@1|root,COG0745@2|Bacteria,1TQSA@1239|Firmicutes,24F54@186801|Clostridia,3Y2DR@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NGKEMLHH_03545	411459.RUMOBE_01861	0.0	908.0	COG0642@1|root,COG2205@2|Bacteria,1TRD2@1239|Firmicutes,247M3@186801|Clostridia,3Y0A6@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NGKEMLHH_03546	411459.RUMOBE_01860	0.0	956.0	2CGG8@1|root,2ZB3X@2|Bacteria,1TS7C@1239|Firmicutes,24CYW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03547	411459.RUMOBE_01859	2.72e-205	568.0	28ITJ@1|root,2Z8SG@2|Bacteria,1V0TD@1239|Firmicutes,24AI9@186801|Clostridia,3Y182@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03548	457412.RSAG_00463	1.6e-161	453.0	2C82F@1|root,32X5P@2|Bacteria,1VC9W@1239|Firmicutes,24PT0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03549	457412.RSAG_00462	1.06e-173	484.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,3WIM2@541000|Ruminococcaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NGKEMLHH_03550	411459.RUMOBE_01856	5.61e-81	251.0	COG1361@1|root,COG1361@2|Bacteria,1TQHN@1239|Firmicutes,24BUH@186801|Clostridia,3Y0PV@572511|Blautia	186801|Clostridia	M	COG NOG29868 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
NGKEMLHH_03551	457412.RSAG_00461	1.03e-165	474.0	COG1361@1|root,COG1361@2|Bacteria,1TQHN@1239|Firmicutes,24BUH@186801|Clostridia,3WK3W@541000|Ruminococcaceae	186801|Clostridia	M	COG NOG29868 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
NGKEMLHH_03552	457412.RSAG_00460	6.31e-160	449.0	2CAM3@1|root,33QBQ@2|Bacteria,1VU0Q@1239|Firmicutes,24Y3I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03553	457412.RSAG_00459	1.17e-61	191.0	COG3385@1|root,COG3385@2|Bacteria,1UNGW@1239|Firmicutes,24BMP@186801|Clostridia	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_03555	457412.RSAG_02305	2.28e-114	329.0	COG1595@1|root,COG1595@2|Bacteria,1VGKP@1239|Firmicutes,24RUX@186801|Clostridia,3WKQD@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NGKEMLHH_03556	1121115.AXVN01000131_gene738	1.28e-95	283.0	2E509@1|root,32ZTU@2|Bacteria,1VB4U@1239|Firmicutes,249Y2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03557	1121115.AXVN01000131_gene738	3.29e-36	129.0	2E509@1|root,32ZTU@2|Bacteria,1VB4U@1239|Firmicutes,249Y2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03558	457396.CSBG_02888	3.82e-21	97.4	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,36FRE@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NGKEMLHH_03559	515622.bpr_I1923	5.64e-177	496.0	COG3645@1|root,COG3645@2|Bacteria,1UBCR@1239|Firmicutes,24DJ3@186801|Clostridia,4C0TR@830|Butyrivibrio	186801|Clostridia	S	Psort location Cytoplasmic, score	dinD	-	-	ko:K14623	-	-	-	-	ko00000,ko03400	-	-	-	Bro-N
NGKEMLHH_03560	397287.C807_02688	7.71e-34	121.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,24GMD@186801|Clostridia,27MW4@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NGKEMLHH_03561	435590.BVU_0323	3.57e-168	474.0	2F8ZB@1|root,341B2@2|Bacteria,4P4SF@976|Bacteroidetes,2FUV2@200643|Bacteroidia,4AS8V@815|Bacteroidaceae	976|Bacteroidetes	S	TolB-like 6-blade propeller-like	-	-	-	-	-	-	-	-	-	-	-	-	TolB_like
NGKEMLHH_03562	1235788.C802_01209	2.56e-57	189.0	2BZEB@1|root,2ZMZD@2|Bacteria,4NMWK@976|Bacteroidetes,2FQNP@200643|Bacteroidia,4APC0@815|Bacteroidaceae	976|Bacteroidetes	S	protein BT4048 SWALL AAO79153 (EMBL AE016943) (373 aa) fasta scores E()	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
NGKEMLHH_03563	457412.RSAG_04741	2.15e-68	217.0	COG1106@1|root,COG1106@2|Bacteria,1TPJN@1239|Firmicutes,249WF@186801|Clostridia,3WIMF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
NGKEMLHH_03564	411468.CLOSCI_02125	1.12e-07	52.4	2ASKI@1|root,31I16@2|Bacteria,1VI67@1239|Firmicutes,24A56@186801|Clostridia,2242S@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03565	457412.RSAG_00437	9.55e-70	209.0	2ASKI@1|root,31I16@2|Bacteria,1VI67@1239|Firmicutes,24A56@186801|Clostridia,3WJSX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03566	1506994.JNLQ01000005_gene3978	2.79e-111	349.0	COG1002@1|root,COG1002@2|Bacteria,1TRZH@1239|Firmicutes,249I6@186801|Clostridia,4C0Z2@830|Butyrivibrio	186801|Clostridia	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
NGKEMLHH_03567	435590.BVU_2667	0.0	944.0	COG2244@1|root,COG2244@2|Bacteria,4NEGZ@976|Bacteroidetes,2FWBF@200643|Bacteroidia,4ATKW@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MatE,Polysacc_synt
NGKEMLHH_03568	1121115.AXVN01000005_gene2234	6.1e-189	524.0	28P0Q@1|root,2ZBX8@2|Bacteria,1V22P@1239|Firmicutes,248XV@186801|Clostridia,3XZCT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03569	1121115.AXVN01000005_gene2233	7.3e-157	447.0	COG3007@1|root,COG3007@2|Bacteria,1TWIF@1239|Firmicutes,249TW@186801|Clostridia,3XZSQ@572511|Blautia	186801|Clostridia	I	Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA)	fabV	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
NGKEMLHH_03571	457412.RSAG_02233	1.52e-206	571.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ8Y@1239|Firmicutes,248SM@186801|Clostridia,3WJQB@541000|Ruminococcaceae	186801|Clostridia	K	PFAM AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NGKEMLHH_03572	457412.RSAG_02232	0.0	963.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NGKEMLHH_03573	457412.RSAG_02231	0.0	1659.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3WGPN@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
NGKEMLHH_03574	1121115.AXVN01000125_gene3811	0.0	1016.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3XYYI@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
NGKEMLHH_03575	1121115.AXVN01000125_gene3810	2.1e-129	368.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3XZRY@572511|Blautia	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
NGKEMLHH_03576	1121115.AXVN01000125_gene3809	9.79e-183	508.0	COG0106@1|root,COG0106@2|Bacteria,1TPIN@1239|Firmicutes,249HJ@186801|Clostridia,3XYK1@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisA	-	-	-	-	-	-	-	-	-	-	-	His_biosynth
NGKEMLHH_03577	397290.C810_03985	1.73e-29	106.0	2DAN3@1|root,32TVS@2|Bacteria,1VABD@1239|Firmicutes,24N3S@186801|Clostridia,27NRT@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NGKEMLHH_03578	483218.BACPEC_00879	1.89e-115	334.0	COG1396@1|root,COG1396@2|Bacteria,1TRKK@1239|Firmicutes,24C0F@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_03579	411459.RUMOBE_00498	1.31e-187	523.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,3XYMF@572511|Blautia	186801|Clostridia	P	COG COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
NGKEMLHH_03580	658086.HMPREF0994_01644	1.92e-238	656.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,27J17@186928|unclassified Lachnospiraceae	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
NGKEMLHH_03581	658086.HMPREF0994_01643	4.7e-52	164.0	COG1925@1|root,COG1925@2|Bacteria,1TTT1@1239|Firmicutes,24PF9@186801|Clostridia,27PIE@186928|unclassified Lachnospiraceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NGKEMLHH_03582	1121115.AXVN01000199_gene606	4.94e-249	684.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3XYYW@572511|Blautia	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
NGKEMLHH_03583	511680.BUTYVIB_02280	2.24e-133	393.0	28HPA@1|root,2Z7XB@2|Bacteria,1TRBX@1239|Firmicutes,24AUG@186801|Clostridia,4C0W2@830|Butyrivibrio	186801|Clostridia	S	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NGKEMLHH_03584	1121115.AXVN01000123_gene2860	4.1e-162	454.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,3XZIA@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NGKEMLHH_03585	457412.RSAG_01520	2.31e-20	88.6	COG5464@1|root,COG5464@2|Bacteria,1TYDT@1239|Firmicutes,24EGK@186801|Clostridia,3WKU9@541000|Ruminococcaceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,HTH_7,PDDEXK_2
NGKEMLHH_03588	667015.Bacsa_1753	7.74e-48	162.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,2FNF3@200643|Bacteroidia,4AKZP@815|Bacteroidaceae	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
NGKEMLHH_03589	411469.EUBHAL_01068	7e-209	581.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,25VF4@186806|Eubacteriaceae	186801|Clostridia	S	Bile acid transporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
NGKEMLHH_03590	658086.HMPREF0994_02991	2.49e-309	849.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,27JM8@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
NGKEMLHH_03591	1121115.AXVN01000048_gene1275	1.64e-59	203.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,SBP_bac_3
NGKEMLHH_03592	1121115.AXVN01000048_gene1276	1.32e-61	188.0	2DZI1@1|root,32VB8@2|Bacteria,1VAA5@1239|Firmicutes,24KYU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03593	1121115.AXVN01000048_gene1277	1.98e-204	566.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3XZ6G@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
NGKEMLHH_03594	457412.RSAG_01574	5.21e-195	542.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,3WHZF@541000|Ruminococcaceae	186801|Clostridia	C	PFAM nitrite and sulphite reductase 4Fe-4S	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
NGKEMLHH_03595	1121115.AXVN01000048_gene1279	1.23e-52	165.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia,3Y205@572511|Blautia	186801|Clostridia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
NGKEMLHH_03596	457412.RSAG_01572	1.72e-69	209.0	COG0526@1|root,COG0526@2|Bacteria,1UG1U@1239|Firmicutes,24SF7@186801|Clostridia,3WKHR@541000|Ruminococcaceae	186801|Clostridia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NGKEMLHH_03597	457412.RSAG_01571	3.42e-41	135.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia,3WKGM@541000|Ruminococcaceae	186801|Clostridia	H	TIGRFAM thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
NGKEMLHH_03598	1121115.AXVN01000048_gene1282	5.7e-198	548.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,3Y0YS@572511|Blautia	186801|Clostridia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
NGKEMLHH_03599	457412.RSAG_01569	9.72e-103	296.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,3WJ1M@541000|Ruminococcaceae	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
NGKEMLHH_03600	457412.RSAG_01568	0.0	1138.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WH9N@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HisKA_7TM,Response_reg,SBP_bac_3
NGKEMLHH_03601	1121115.AXVN01000048_gene1285	0.0	1033.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia	186801|Clostridia	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
NGKEMLHH_03602	411483.FAEPRAA2165_00525	1.09e-100	293.0	28HBX@1|root,2Z7NW@2|Bacteria,1UZQ2@1239|Firmicutes,248AZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03603	796945.HMPREF1145_1214	1.3e-190	535.0	COG1106@1|root,COG1106@2|Bacteria,1UDAD@1239|Firmicutes,24B5G@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
NGKEMLHH_03606	457412.RSAG_02578	4.82e-178	496.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,3WG8S@541000|Ruminococcaceae	186801|Clostridia	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
NGKEMLHH_03607	1121115.AXVN01000008_gene2717	3.7e-16	72.0	2FAZC@1|root,34364@2|Bacteria,1VXA9@1239|Firmicutes,252GU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03608	457412.RSAG_02581	1.73e-109	327.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3WH1A@541000|Ruminococcaceae	186801|Clostridia	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
NGKEMLHH_03609	658086.HMPREF0994_03067	1.07e-112	341.0	COG0119@1|root,COG2207@1|root,COG0119@2|Bacteria,COG2207@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,27IAK@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
NGKEMLHH_03610	658086.HMPREF0994_03066	9.7e-133	376.0	COG1309@1|root,COG1309@2|Bacteria,1V7CM@1239|Firmicutes,24K3K@186801|Clostridia,27N2A@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NGKEMLHH_03611	658088.HMPREF0987_01890	2.12e-59	183.0	2AZMT@1|root,31RWJ@2|Bacteria,1V8FY@1239|Firmicutes,24JSC@186801|Clostridia,27NA6@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03612	33035.JPJF01000072_gene4396	2.78e-153	434.0	28MJQ@1|root,2ZAW4@2|Bacteria,1UF72@1239|Firmicutes,24YQA@186801|Clostridia,3XZNI@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4316)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4316,YodL
NGKEMLHH_03613	33035.JPJF01000072_gene4397	1.03e-50	160.0	2C2HG@1|root,32RAG@2|Bacteria,1V8H6@1239|Firmicutes,252A1@186801|Clostridia,3Y0M3@572511|Blautia	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
NGKEMLHH_03614	1121115.AXVN01000004_gene1962	2.07e-61	189.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24T7M@186801|Clostridia,3Y25G@572511|Blautia	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
NGKEMLHH_03615	1121115.AXVN01000004_gene1967	2.31e-95	278.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,3Y024@572511|Blautia	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
NGKEMLHH_03616	1121115.AXVN01000002_gene1392	0.0	885.0	COG4733@1|root,COG5279@1|root,COG4733@2|Bacteria,COG5279@2|Bacteria,1V1JE@1239|Firmicutes,24GTB@186801|Clostridia,3Y115@572511|Blautia	186801|Clostridia	M	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03617	97139.C824_03803	6.65e-81	254.0	28M3R@1|root,32UZU@2|Bacteria,1VBVW@1239|Firmicutes,24J58@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03619	457412.RSAG_00675	3.41e-80	249.0	COG2211@1|root,COG2211@2|Bacteria,1TR5B@1239|Firmicutes,249ZF@186801|Clostridia,3WGZS@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NGKEMLHH_03620	411459.RUMOBE_00755	1.66e-78	240.0	COG1309@1|root,COG1309@2|Bacteria,1TYNZ@1239|Firmicutes,24IV3@186801|Clostridia	186801|Clostridia	K	transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NGKEMLHH_03621	411459.RUMOBE_03129	7.9e-95	287.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,3Y1MC@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
NGKEMLHH_03622	457412.RSAG_02066	3.83e-68	206.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,3WJM5@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NGKEMLHH_03623	1121115.AXVN01000079_gene2735	1.23e-223	615.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes,24CTG@186801|Clostridia,3Y1A4@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03624	1121115.AXVN01000079_gene2736	1.57e-37	126.0	2C4UK@1|root,346TK@2|Bacteria,1W0FK@1239|Firmicutes,2530T@186801|Clostridia,3Y21U@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03625	1121115.AXVN01000079_gene2737	1.44e-35	120.0	2E7J1@1|root,33DKE@2|Bacteria,1VM3N@1239|Firmicutes,24VIG@186801|Clostridia,3Y0W5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03626	1121115.AXVN01000079_gene2738	5.72e-200	553.0	2BYUU@1|root,2Z7P3@2|Bacteria,1UYDK@1239|Firmicutes,249UN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03627	1121115.AXVN01000079_gene2739	4.04e-149	419.0	2C0W2@1|root,306ZY@2|Bacteria,1V5YY@1239|Firmicutes,24I0Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_7,MqsA_antitoxin
NGKEMLHH_03628	1121115.AXVN01000079_gene2740	5.86e-131	372.0	COG0400@1|root,COG0400@2|Bacteria,1TXQZ@1239|Firmicutes,24GGB@186801|Clostridia,3Y0NJ@572511|Blautia	186801|Clostridia	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03629	457412.RSAG_02087	0.0	906.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,3WHQP@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
NGKEMLHH_03630	457412.RSAG_02088	8.26e-81	243.0	COG1028@1|root,COG1028@2|Bacteria,1V0T9@1239|Firmicutes,24ASP@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
NGKEMLHH_03631	1121115.AXVN01000079_gene2742	3.61e-36	127.0	COG1028@1|root,COG1028@2|Bacteria,1V0T9@1239|Firmicutes,24ASP@186801|Clostridia,3Y12C@572511|Blautia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
NGKEMLHH_03632	1121115.AXVN01000079_gene2743	5.17e-123	351.0	COG3275@1|root,COG3275@2|Bacteria,1UZUT@1239|Firmicutes,25BAU@186801|Clostridia,3Y2E5@572511|Blautia	186801|Clostridia	T	phosphorelay sensor kinase activity	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	ECF_trnsprt
NGKEMLHH_03633	1121115.AXVN01000079_gene2744	1.59e-241	663.0	COG1957@1|root,COG1957@2|Bacteria,1TRQQ@1239|Firmicutes,25C8Y@186801|Clostridia,3Y2EI@572511|Blautia	186801|Clostridia	F	Inosine-uridine preferring nucleoside hydrolase	iunH	-	3.2.2.1	ko:K01239,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
NGKEMLHH_03634	411459.RUMOBE_01243	1.13e-126	360.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3XZX6@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
NGKEMLHH_03635	411459.RUMOBE_01242	2.58e-163	459.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,3XYMC@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NGKEMLHH_03636	1121115.AXVN01000008_gene2668	2.09e-160	450.0	COG1122@1|root,COG1122@2|Bacteria,1V16T@1239|Firmicutes,25B0D@186801|Clostridia,3Y12Z@572511|Blautia	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
NGKEMLHH_03637	457412.RSAG_02539	6.2e-85	253.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia,3WIP4@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
NGKEMLHH_03638	435590.BVU_2525	8.72e-258	707.0	COG0582@1|root,COG0582@2|Bacteria,4P15N@976|Bacteroidetes,2FMSS@200643|Bacteroidia,4AKIM@815|Bacteroidaceae	976|Bacteroidetes	L	Phage integrase SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_5,Phage_integrase
NGKEMLHH_03639	457412.RSAG_02268	0.0	951.0	COG1680@1|root,COG1680@2|Bacteria,1TR9E@1239|Firmicutes,2480P@186801|Clostridia,3WG8D@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
NGKEMLHH_03640	397291.C804_02849	6.77e-77	241.0	COG2310@1|root,COG2310@2|Bacteria,1V26C@1239|Firmicutes,24GMA@186801|Clostridia,27N1D@186928|unclassified Lachnospiraceae	186801|Clostridia	T	TerD domain	-	-	-	-	-	-	-	-	-	-	-	-	TerD
NGKEMLHH_03642	1121115.AXVN01000119_gene3271	1.01e-114	355.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1TS5R@1239|Firmicutes,24AWW@186801|Clostridia	186801|Clostridia	L	Type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
NGKEMLHH_03643	457412.RSAG_01801	1.98e-132	387.0	COG1061@1|root,COG1061@2|Bacteria,1TS5R@1239|Firmicutes,24AWW@186801|Clostridia,3WH13@541000|Ruminococcaceae	186801|Clostridia	L	Type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
NGKEMLHH_03644	742733.HMPREF9469_00243	3.9e-158	455.0	2C5T8@1|root,2ZB5V@2|Bacteria,1TSS6@1239|Firmicutes,258ZQ@186801|Clostridia,222QR@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03645	1121115.AXVN01000002_gene1344	2.9e-187	520.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia,3Y0A0@572511|Blautia	186801|Clostridia	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
NGKEMLHH_03646	457412.RSAG_00945	7.77e-151	424.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,24RQ3@186801|Clostridia,3WIX4@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
NGKEMLHH_03647	1121115.AXVN01000002_gene1342	2.15e-63	194.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24T7M@186801|Clostridia,3Y25G@572511|Blautia	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
NGKEMLHH_03648	1121115.AXVN01000002_gene1341	0.0	4343.0	COG1020@1|root,COG3320@1|root,COG1020@2|Bacteria,COG3320@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,3Y1GF@572511|Blautia	186801|Clostridia	Q	AMP-binding enzyme C-terminal domain	-	-	-	ko:K04784,ko:K12240	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,NAD_binding_4,PP-binding,Thioesterase
NGKEMLHH_03649	1121115.AXVN01000002_gene1341	1.5e-238	726.0	COG1020@1|root,COG3320@1|root,COG1020@2|Bacteria,COG3320@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,3Y1GF@572511|Blautia	186801|Clostridia	Q	AMP-binding enzyme C-terminal domain	-	-	-	ko:K04784,ko:K12240	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,NAD_binding_4,PP-binding,Thioesterase
NGKEMLHH_03650	1121115.AXVN01000010_gene2758	8.29e-151	427.0	COG1082@1|root,COG1082@2|Bacteria,1UZC1@1239|Firmicutes,24DNU@186801|Clostridia,3Y08D@572511|Blautia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	ko:K10709	-	-	-	-	ko00000	-	-	-	AP_endonuc_2
NGKEMLHH_03651	1121115.AXVN01000041_gene2601	3.87e-305	830.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,3XYT4@572511|Blautia	186801|Clostridia	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NGKEMLHH_03653	742765.HMPREF9457_02303	5.61e-106	318.0	COG1476@1|root,COG1476@2|Bacteria,1V7TA@1239|Firmicutes,2496Q@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NGKEMLHH_03654	411459.RUMOBE_03341	1.18e-10	59.7	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,25KA6@186801|Clostridia,3Y1KT@572511|Blautia	186801|Clostridia	P	COG COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
NGKEMLHH_03655	457412.RSAG_01464	6.72e-152	426.0	2BC4V@1|root,325PN@2|Bacteria,1URQ2@1239|Firmicutes,24ZYA@186801|Clostridia,3WQB6@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
NGKEMLHH_03656	457412.RSAG_01465	1.4e-135	389.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,3WGDH@541000|Ruminococcaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
NGKEMLHH_03657	944565.HMPREF9127_0835	1.16e-86	273.0	COG1196@1|root,COG1196@2|Bacteria,1U46F@1239|Firmicutes,24C5R@186801|Clostridia,22H4Q@1570339|Peptoniphilaceae	186801|Clostridia	D	the current gene model (or a revised gene model) may contain a premature stop	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03658	658086.HMPREF0994_05424	5.65e-119	340.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,27JIP@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
NGKEMLHH_03659	658086.HMPREF0994_05107	2.07e-229	632.0	COG0715@1|root,COG0715@2|Bacteria,1UYBA@1239|Firmicutes,24D4Q@186801|Clostridia,27TGN@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,OmpA
NGKEMLHH_03660	1121115.AXVN01000007_gene3557	8.11e-131	372.0	28N9F@1|root,2ZBDG@2|Bacteria,1V0YX@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4433
NGKEMLHH_03661	1232453.BAIF02000121_gene163	4.26e-163	476.0	COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,2494Y@186801|Clostridia,26AHA@186813|unclassified Clostridiales	186801|Clostridia	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH,RIO1,WaaY
NGKEMLHH_03662	1121115.AXVN01000068_gene3402	9.92e-110	316.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3XZVD@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
NGKEMLHH_03663	1121115.AXVN01000068_gene3401	6.93e-64	197.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3XZZA@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
NGKEMLHH_03664	1121115.AXVN01000068_gene3400	0.0	1305.0	COG5434@1|root,COG5434@2|Bacteria,1V8MX@1239|Firmicutes,257MV@186801|Clostridia,3Y1ZG@572511|Blautia	186801|Clostridia	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
NGKEMLHH_03665	457412.RSAG_01500	0.0	2521.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,3WH6H@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
NGKEMLHH_03666	457412.RSAG_01499	0.0	2380.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
NGKEMLHH_03667	457412.RSAG_01498	0.0	1170.0	COG0515@1|root,COG0515@2|Bacteria,1V2ZP@1239|Firmicutes,24G58@186801|Clostridia,3WIKP@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF5050,PASTA,Pkinase,SH3_3
NGKEMLHH_03668	457412.RSAG_01497	2.62e-200	554.0	COG0631@1|root,COG0631@2|Bacteria,1VXKJ@1239|Firmicutes,2522X@186801|Clostridia,3WK7B@541000|Ruminococcaceae	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PP2C,PP2C_2
NGKEMLHH_03669	1121115.AXVN01000068_gene3395	4.15e-298	813.0	2CF3U@1|root,33TFS@2|Bacteria,1VS98@1239|Firmicutes,24YVZ@186801|Clostridia,3XZ6U@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03670	33035.JPJF01000008_gene1192	6.68e-06	48.1	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3XZ8Q@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NGKEMLHH_03671	457412.RSAG_01494	4.73e-209	584.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	bla1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
NGKEMLHH_03672	1121115.AXVN01000068_gene3392	1.09e-227	629.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,3XZ3C@572511|Blautia	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	lytC_3	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NGKEMLHH_03673	457412.RSAG_04528	1.34e-25	94.7	298ED@1|root,2ZVJK@2|Bacteria,1W2SQ@1239|Firmicutes,2571M@186801|Clostridia	457412.RSAG_04528|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03674	1121115.AXVN01000065_gene675	4.34e-90	264.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3XZTZ@572511|Blautia	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
NGKEMLHH_03675	457412.RSAG_01491	6.62e-105	303.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,3WGPA@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
NGKEMLHH_03677	1121115.AXVN01000122_gene2859	1.09e-154	435.0	2DMJ6@1|root,32RY3@2|Bacteria,1VBBI@1239|Firmicutes,24SVX@186801|Clostridia,3Y00H@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
NGKEMLHH_03678	1121115.AXVN01000122_gene2858	1.12e-285	783.0	2C3W5@1|root,2ZBIU@2|Bacteria,1UZRE@1239|Firmicutes,24BHB@186801|Clostridia,3XYH0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03679	1121115.AXVN01000122_gene2857	2.79e-284	781.0	COG1388@1|root,COG1388@2|Bacteria,1V4FJ@1239|Firmicutes,24IPI@186801|Clostridia,3XZF7@572511|Blautia	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
NGKEMLHH_03680	1121115.AXVN01000122_gene2856	4.45e-128	364.0	2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,24JCA@186801|Clostridia,3Y027@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1256
NGKEMLHH_03681	1121115.AXVN01000122_gene2855	1.38e-222	613.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3XZRN@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
NGKEMLHH_03682	1121115.AXVN01000122_gene2854	9.51e-202	558.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
NGKEMLHH_03683	1121115.AXVN01000122_gene2853	8.69e-149	419.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,3XYWX@572511|Blautia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
NGKEMLHH_03684	457412.RSAG_02634	1.1e-258	709.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia,3WIXJ@541000|Ruminococcaceae	186801|Clostridia	K	Periplasmic binding protein domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NGKEMLHH_03685	1121115.AXVN01000122_gene2851	8.84e-140	395.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3XZEE@572511|Blautia	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
NGKEMLHH_03686	1121115.AXVN01000122_gene2850	3.98e-72	217.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3Y02F@572511|Blautia	186801|Clostridia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
NGKEMLHH_03687	272559.BF9343_3219	2.95e-65	211.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
NGKEMLHH_03688	180332.JTGN01000006_gene3315	5.53e-92	282.0	COG1653@1|root,COG1653@2|Bacteria,1TT6Y@1239|Firmicutes,24F48@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NGKEMLHH_03689	180332.JTGN01000006_gene3314	7.09e-169	476.0	COG1175@1|root,COG1175@2|Bacteria,1UYMQ@1239|Firmicutes,24C91@186801|Clostridia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NGKEMLHH_03690	1121115.AXVN01000001_gene1147	3.47e-147	414.0	COG0731@1|root,COG0731@2|Bacteria,1UJ6S@1239|Firmicutes,25EWY@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
NGKEMLHH_03691	457412.RSAG_01274	6.94e-100	291.0	COG4720@1|root,COG4720@2|Bacteria,1V8B5@1239|Firmicutes,24J8T@186801|Clostridia,3WJ8C@541000|Ruminococcaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
NGKEMLHH_03692	1121115.AXVN01000010_gene2774	1.21e-168	476.0	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03693	1121115.AXVN01000010_gene2775	1.61e-88	259.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia,3Y06A@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
NGKEMLHH_03695	411459.RUMOBE_02894	3.94e-202	575.0	COG5427@1|root,COG5427@2|Bacteria,1UXXM@1239|Firmicutes,24EF9@186801|Clostridia,3XZFE@572511|Blautia	186801|Clostridia	M	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03696	457412.RSAG_00263	5.87e-158	443.0	28HI8@1|root,2Z9QV@2|Bacteria,1UZZ2@1239|Firmicutes,24IH2@186801|Clostridia,3WJDW@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
NGKEMLHH_03697	1121115.AXVN01000147_gene3487	2.14e-126	361.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,3Y039@572511|Blautia	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
NGKEMLHH_03698	457412.RSAG_01667	0.0	1019.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,3WM6D@541000|Ruminococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
NGKEMLHH_03699	457412.RSAG_01668	9.79e-143	403.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,3WIZU@541000|Ruminococcaceae	186801|Clostridia	S	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
NGKEMLHH_03700	457412.RSAG_01670	5.26e-133	376.0	COG5423@1|root,COG5423@2|Bacteria,1V8Y4@1239|Firmicutes,24EAF@186801|Clostridia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NGKEMLHH_03701	457412.RSAG_01671	0.0	1130.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3WI2J@541000|Ruminococcaceae	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
NGKEMLHH_03702	1121115.AXVN01000014_gene1247	5.21e-138	391.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,3Y0XR@572511|Blautia	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
NGKEMLHH_03703	1121115.AXVN01000014_gene1246	2.32e-194	539.0	COG1410@1|root,COG1410@2|Bacteria,1UV7K@1239|Firmicutes,25CEH@186801|Clostridia,3Y0ZA@572511|Blautia	186801|Clostridia	E	Pterin binding enzyme	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
NGKEMLHH_03705	1121115.AXVN01000014_gene1245	2.4e-268	732.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,3Y1E6@572511|Blautia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NGKEMLHH_03706	658086.HMPREF0994_00915	3.31e-150	422.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,27ITQ@186928|unclassified Lachnospiraceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
NGKEMLHH_03707	1256908.HMPREF0373_00680	7e-108	310.0	2C7BX@1|root,2Z7TG@2|Bacteria,1UY1D@1239|Firmicutes,24ERX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03708	500632.CLONEX_03500	1.07e-206	584.0	2FB6A@1|root,343CK@2|Bacteria,1W0K8@1239|Firmicutes,253UA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03709	556261.HMPREF0240_03127	6.58e-76	229.0	COG0500@1|root,COG2226@2|Bacteria,1TVU2@1239|Firmicutes,24AIJ@186801|Clostridia,36IVM@31979|Clostridiaceae	186801|Clostridia	Q	Methyltransferase domain protein	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
NGKEMLHH_03710	556261.HMPREF0240_03128	4e-54	170.0	2ADC6@1|root,3131Q@2|Bacteria,1UT8P@1239|Firmicutes,251WC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03711	742735.HMPREF9467_03509	3.38e-76	227.0	2BAQE@1|root,3245B@2|Bacteria,1V86A@1239|Firmicutes,24MCZ@186801|Clostridia,222Z9@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03712	1121115.AXVN01000134_gene414	5.38e-286	781.0	COG1171@1|root,COG1171@2|Bacteria,1TR70@1239|Firmicutes,2485T@186801|Clostridia,3XZ80@572511|Blautia	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	dpaL	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
NGKEMLHH_03713	694440.JOMF01000006_gene391	2.96e-10	65.5	COG0110@1|root,arCOG01848@2157|Archaea	2157|Archaea	E	COG0110 Acetyltransferase (isoleucine patch superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
NGKEMLHH_03716	622312.ROSEINA2194_03230	1.05e-118	342.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
NGKEMLHH_03717	585394.RHOM_16915	1.99e-17	82.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
NGKEMLHH_03718	585394.RHOM_16915	2.83e-80	251.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
NGKEMLHH_03719	457412.RSAG_01463	0.0	1015.0	28I9Q@1|root,2Z8CD@2|Bacteria,1TQ4H@1239|Firmicutes,24B8Q@186801|Clostridia,3WREU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03720	457412.RSAG_01462	3.36e-165	463.0	28MFF@1|root,2ZASX@2|Bacteria,1TQD0@1239|Firmicutes,24996@186801|Clostridia,3WMED@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03721	457412.RSAG_01461	0.0	2712.0	COG1196@1|root,COG1196@2|Bacteria,1TR05@1239|Firmicutes,24BXV@186801|Clostridia,3WJQR@541000|Ruminococcaceae	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03723	1121115.AXVN01000069_gene2315	4.73e-118	337.0	COG1595@1|root,COG1595@2|Bacteria,1TPJJ@1239|Firmicutes,24JUX@186801|Clostridia,3Y0D0@572511|Blautia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NGKEMLHH_03724	1121115.AXVN01000069_gene2316	1.75e-148	418.0	29XH4@1|root,30J7T@2|Bacteria,1UVPT@1239|Firmicutes,2503Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03725	1121115.AXVN01000069_gene2317	6.71e-193	536.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia,3XZ72@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NGKEMLHH_03726	33035.JPJF01000003_gene1848	4.74e-187	532.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,3Y197@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
NGKEMLHH_03727	457412.RSAG_01910	2.93e-198	550.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,24931@186801|Clostridia,3WIEJ@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	licT	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
NGKEMLHH_03728	1121115.AXVN01000084_gene1836	4.88e-198	548.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,3XYU0@572511|Blautia	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
NGKEMLHH_03729	1121115.AXVN01000084_gene1835	4.7e-86	259.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3XZ9N@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NGKEMLHH_03735	411463.EUBVEN_02573	1.1e-134	394.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia,25VNZ@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_03736	1121115.AXVN01000005_gene2229	2.5e-52	165.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3Y0EQ@572511|Blautia	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
NGKEMLHH_03737	1121115.AXVN01000005_gene2228	5.16e-87	262.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,3XZMT@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
NGKEMLHH_03738	457412.RSAG_01928	2.15e-281	768.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
NGKEMLHH_03739	457412.RSAG_00670	0.0	876.0	COG2733@1|root,COG2733@2|Bacteria,1UKI3@1239|Firmicutes,24WBV@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
NGKEMLHH_03740	457412.RSAG_00820	1.07e-26	103.0	COG4734@1|root,COG4734@2|Bacteria,1UZZ6@1239|Firmicutes,24DE1@186801|Clostridia	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NGKEMLHH_03741	457412.RSAG_02481	8.17e-52	163.0	2EC32@1|root,33621@2|Bacteria,1VIVU@1239|Firmicutes,24Q0K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
NGKEMLHH_03742	457412.RSAG_02482	3.04e-110	317.0	28IR3@1|root,2Z8QN@2|Bacteria,1UKI8@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791,DUF3990
NGKEMLHH_03743	457412.RSAG_02483	1.14e-48	155.0	2DN0F@1|root,32UQJ@2|Bacteria,1VBR6@1239|Firmicutes,24NWZ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
NGKEMLHH_03744	586413.CCDL010000001_gene1183	0.000388	50.8	COG0772@1|root,COG0772@2|Bacteria,1V1V4@1239|Firmicutes,4HCZ8@91061|Bacilli	91061|Bacilli	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
NGKEMLHH_03748	1122917.KB899659_gene5296	5.1e-37	128.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,4IR4T@91061|Bacilli,276N1@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
NGKEMLHH_03749	397291.C804_04364	6.37e-39	154.0	COG5305@1|root,COG5305@2|Bacteria,1UXXF@1239|Firmicutes,25Q2P@186801|Clostridia,27NZC@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
NGKEMLHH_03750	411467.BACCAP_02989	1.91e-106	313.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,249HV@186801|Clostridia,26AMU@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03751	500632.CLONEX_01035	6.61e-152	436.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia	186801|Clostridia	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
NGKEMLHH_03753	1121097.JCM15093_1945	2.22e-68	228.0	2EHDH@1|root,33B5C@2|Bacteria,4PAE1@976|Bacteroidetes,2FWQ0@200643|Bacteroidia	976|Bacteroidetes	S	FRG domain	-	-	-	-	-	-	-	-	-	-	-	-	FRG
NGKEMLHH_03754	1121115.AXVN01000027_gene577	3.83e-23	89.4	2EPXM@1|root,33HI5@2|Bacteria,1VNMZ@1239|Firmicutes,24W4H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03755	1121115.AXVN01000027_gene575	1.6e-47	156.0	28K00@1|root,2Z9Q0@2|Bacteria,1TR6B@1239|Firmicutes,24EVF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03756	1232447.BAHW02000055_gene3186	1.34e-73	231.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
NGKEMLHH_03758	622312.ROSEINA2194_01251	1.37e-48	160.0	2C6U1@1|root,30XIE@2|Bacteria,1V4EP@1239|Firmicutes,24J3E@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
NGKEMLHH_03761	1121115.AXVN01000083_gene2467	2.81e-141	402.0	COG1961@1|root,COG1961@2|Bacteria,1VU49@1239|Firmicutes,24ZW8@186801|Clostridia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase
NGKEMLHH_03762	457412.RSAG_01555	2.64e-266	731.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NGKEMLHH_03763	457412.RSAG_02534	2e-154	432.0	COG2819@1|root,COG2819@2|Bacteria,1V1TT@1239|Firmicutes,24GDE@186801|Clostridia,3WIMM@541000|Ruminococcaceae	186801|Clostridia	S	hydrolase of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
NGKEMLHH_03764	1121115.AXVN01000008_gene2673	1.06e-246	684.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3XZGV@572511|Blautia	186801|Clostridia	E	Psort location Cellwall, score	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NGKEMLHH_03765	435590.BVU_3973	2.09e-149	424.0	COG1216@1|root,COG1216@2|Bacteria,4NT7I@976|Bacteroidetes,2FRV9@200643|Bacteroidia,4AQ4S@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NGKEMLHH_03766	1121115.AXVN01000032_gene390	4.53e-283	773.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia,3XYIC@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
NGKEMLHH_03767	1121115.AXVN01000032_gene391	7.09e-228	629.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,3XYTC@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
NGKEMLHH_03768	457412.RSAG_00169	2.36e-111	320.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3WIDY@541000|Ruminococcaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
NGKEMLHH_03769	457412.RSAG_00167	1.43e-190	530.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,3WGZ7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
NGKEMLHH_03770	1121115.AXVN01000032_gene394	2.05e-42	139.0	COG4224@1|root,COG4224@2|Bacteria,1TUAX@1239|Firmicutes,24QS9@186801|Clostridia,3Y0QD@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
NGKEMLHH_03771	1121115.AXVN01000032_gene395	1.28e-132	375.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,3XZW4@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
NGKEMLHH_03772	457412.RSAG_00164	1.97e-295	806.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,3WH60@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
NGKEMLHH_03773	1121115.AXVN01000032_gene397	0.0	916.0	2DUK2@1|root,33R10@2|Bacteria,1VR47@1239|Firmicutes,24Z5G@186801|Clostridia,3Y0TJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03774	1121115.AXVN01000032_gene398	2.89e-222	612.0	COG2866@1|root,COG2866@2|Bacteria,1UEH5@1239|Firmicutes,25JE5@186801|Clostridia,3Y01R@572511|Blautia	186801|Clostridia	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
NGKEMLHH_03775	397290.C810_04923	2.32e-80	249.0	COG3385@1|root,COG3385@2|Bacteria,1TY08@1239|Firmicutes,24EQW@186801|Clostridia,27JJD@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_03776	397290.C810_04923	1.7e-159	456.0	COG3385@1|root,COG3385@2|Bacteria,1TY08@1239|Firmicutes,24EQW@186801|Clostridia,27JJD@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NGKEMLHH_03777	742733.HMPREF9469_00285	4.64e-96	280.0	2AGPY@1|root,316XK@2|Bacteria,1V241@1239|Firmicutes,25DTM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03778	742733.HMPREF9469_00284	3.68e-97	282.0	2AGPY@1|root,316XK@2|Bacteria,1V241@1239|Firmicutes,24GUS@186801|Clostridia,221TT@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03779	411462.DORLON_01570	7.39e-71	214.0	28PX5@1|root,2ZCH7@2|Bacteria,1V32H@1239|Firmicutes,24GGF@186801|Clostridia,27WRI@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03780	411459.RUMOBE_03454	4.92e-243	666.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,3Y087@572511|Blautia	186801|Clostridia	M	COG COG3049 Penicillin V acylase and related amidases	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
NGKEMLHH_03781	1235788.C802_03748	0.0	907.0	COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,2FPRV@200643|Bacteroidia,4ANMA@815|Bacteroidaceae	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
NGKEMLHH_03782	457412.RSAG_01873	1.95e-114	328.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,24FTH@186801|Clostridia,3WJ8H@541000|Ruminococcaceae	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
NGKEMLHH_03783	457412.RSAG_01874	8.89e-213	586.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,249QG@186801|Clostridia,3WHH9@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
NGKEMLHH_03784	742723.HMPREF9477_00355	1.74e-221	610.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,24DGQ@186801|Clostridia,27M0Q@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
NGKEMLHH_03785	658088.HMPREF0987_00192	3.83e-61	187.0	COG2963@1|root,COG2963@2|Bacteria,1VCC9@1239|Firmicutes,24MCM@186801|Clostridia,27NH9@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
NGKEMLHH_03786	862517.HMPREF9225_0509	1.85e-66	223.0	COG2865@1|root,COG2865@2|Bacteria,1UYYR@1239|Firmicutes,24C3Y@186801|Clostridia,22GZE@1570339|Peptoniphilaceae	186801|Clostridia	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
NGKEMLHH_03787	457412.RSAG_00883	1.78e-201	567.0	COG4145@1|root,COG4145@2|Bacteria,1UJ00@1239|Firmicutes,25F28@186801|Clostridia	186801|Clostridia	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1,2.A.21.2	-	-	SSF
NGKEMLHH_03788	457412.RSAG_00882	5.05e-184	511.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24BWG@186801|Clostridia,3WMNU@541000|Ruminococcaceae	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
NGKEMLHH_03790	457412.RSAG_00880	0.0	1114.0	COG1961@1|root,COG1961@2|Bacteria,1TWK9@1239|Firmicutes,24C30@186801|Clostridia,3WHD6@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NGKEMLHH_03791	457412.RSAG_00879	1.74e-179	514.0	2BHPW@1|root,32BT5@2|Bacteria,1VKP8@1239|Firmicutes,24XAG@186801|Clostridia	186801|Clostridia	S	SANT  SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03792	457412.RSAG_00878	0.0	1938.0	COG1315@1|root,COG1315@2|Bacteria,1TRQX@1239|Firmicutes,24BWZ@186801|Clostridia,3WHD4@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,SLH
NGKEMLHH_03793	1121115.AXVN01000059_gene424	3.59e-242	666.0	2A09X@1|root,30NDB@2|Bacteria,1UK3C@1239|Firmicutes,24HJN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NA37
NGKEMLHH_03794	351627.Csac_2550	7.81e-11	67.4	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSRP@1239|Firmicutes,24CRG@186801|Clostridia	186801|Clostridia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NGKEMLHH_03796	411490.ANACAC_02154	9.82e-62	196.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NGKEMLHH_03797	411490.ANACAC_03011	2.85e-117	358.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
NGKEMLHH_03798	904296.HMPREF9124_0174	2.3e-100	301.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,2PR0U@265975|Oribacterium	186801|Clostridia	P	ABC transporter permease protein	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NGKEMLHH_03799	929506.CbC4_0086	9.26e-45	154.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,36DX1@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NGKEMLHH_03800	1121115.AXVN01000022_gene1745	0.0	1181.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3XYYN@572511|Blautia	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
NGKEMLHH_03801	1121115.AXVN01000022_gene1744	8.49e-52	165.0	2CAIE@1|root,33XMU@2|Bacteria,1VVJ5@1239|Firmicutes,2511G@186801|Clostridia,3Y25M@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NGKEMLHH_03802	457412.RSAG_02145	2.4e-280	765.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,3WGN4@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
NGKEMLHH_03803	1121115.AXVN01000022_gene1742	0.0	1869.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3XYNU@572511|Blautia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
NGKEMLHH_03804	1121115.AXVN01000022_gene1741	1.13e-225	623.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,3XZC7@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
NGKEMLHH_03805	457412.RSAG_02193	1.03e-213	591.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,3WGBT@541000|Ruminococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NGKEMLHH_03806	457412.RSAG_02192	9.63e-306	836.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,3WGX2@541000|Ruminococcaceae	186801|Clostridia	S	xanthine uracil permease family protein K06901	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
NGKEMLHH_03807	1121115.AXVN01000024_gene284	1.81e-312	850.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3XZ7R@572511|Blautia	186801|Clostridia	F	COG COG0402 Cytosine deaminase and related metal-dependent hydrolases	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NGKEMLHH_03808	457412.RSAG_02190	4.8e-240	664.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,25CCK@186801|Clostridia,3WH44@541000|Ruminococcaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NGKEMLHH_03809	1121115.AXVN01000024_gene287	5.34e-81	240.0	2EC8D@1|root,3366W@2|Bacteria,1VEI1@1239|Firmicutes,24WC7@186801|Clostridia	186801|Clostridia	S	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NGKEMLHH_03810	1121115.AXVN01000024_gene288	2.07e-302	823.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3XYUF@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
NGKEMLHH_03811	1121115.AXVN01000081_gene3049	2.02e-222	614.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3XZJF@572511|Blautia	186801|Clostridia	P	COG COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NGKEMLHH_03812	1121115.AXVN01000081_gene3048	0.0	973.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3XZ1W@572511|Blautia	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
NGKEMLHH_03813	457412.RSAG_01759	2.59e-229	632.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3WNJT@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NGKEMLHH_03814	1121115.AXVN01000081_gene3046	1.67e-225	622.0	COG1879@1|root,COG1879@2|Bacteria,1TPWA@1239|Firmicutes,25PX0@186801|Clostridia,3XYI7@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NGKEMLHH_03815	1121115.AXVN01000081_gene3045	0.0	1140.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3XZ6E@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NGKEMLHH_03816	457412.RSAG_01762	0.0	1037.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3WJ5A@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
NGKEMLHH_03817	457412.RSAG_00417	3.4e-279	787.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3WGCC@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NGKEMLHH_03818	457412.RSAG_00416	0.0	910.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3WH2E@541000|Ruminococcaceae	186801|Clostridia	G	Transporter, major facilitator family protein	uidB_2	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NGKEMLHH_03819	1121115.AXVN01000004_gene1983	3.03e-187	520.0	COG2207@1|root,COG2207@2|Bacteria,1TXIY@1239|Firmicutes,248D1@186801|Clostridia,3Y2AU@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NGKEMLHH_03820	1121115.AXVN01000004_gene1982	8.1e-200	553.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,3Y0BE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
NGKEMLHH_03821	457412.RSAG_00413	0.0	1210.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,3WHK3@541000|Ruminococcaceae	186801|Clostridia	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
NGKEMLHH_03822	1121115.AXVN01000004_gene1980	0.0	1123.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XYGZ@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
## 3388 queries scanned
## Total time (seconds): 327.55568742752075
## Rate: 10.34 q/s